Publications of Institute of Radiopharmaceutical Cancer Research

1320 Publications

2019

Time efficient scatter correction for time-of-flight PET: the immediate scatter approximation

Nikulin, P.; Maus, J.; Hofheinz, F.; Lougovski, A.; van den Hoff, J.

Involved research facilities

  • PET-Center

SPECT-Untersuchungen mit dem 123 I-markierten Dopamintransporter-Liganden FP-CIT (DaTSCAN):DGN-Handlungsempfehlung (S1-Leitlinie)

Tatsch, K.; Buchert, R.; Bartenstein, P.; Barthel, H.; Boecker, H.; Brust, P.; Drzezga, A.; La Fougère, C.; Gründer, G.; Grünwald, F.; Krause, B.-J.; Kuwert, T.; Langen, K.-J.; Rominger, A.; Sabri, O.; Schreckenberger, M.; Meyer, P. T.

  • Nuklearmedizin 58(2019)1, 5-16

In vitro and in vivo Human Metabolism of (S)-[18F]Fluspidine – a Radioligand for Imaging σ1 Receptors with Positron Emission Tomography (PET)

Ludwig, F.-A.; Fischer, S.; Houska, R.; Hoepping, A.; Deuther-Conrad, W.; Schepmann, D.; Patt, M.; Meyer, P.; Hesse, S.; Becker, G.-A.; Zientek, F. R.; Steinbach, J.; Wünsch, B.; Sabri, O.; Brust, P.

Limited importance of EphrinA1–ligand, Src kinase, and focal adhesion kinase in EphA2-mediated regulation of metastasis in Mel-Juso and A375 human melanoma cells

Neuber, C.; Herwig, N.; Pietzsch, J.; Belter, B.

Regulation of A375 melanoma cell adhesion and migration by EphB4 and EphrinB2 –insights from co-culture experiments

Neuber, C.; Laube, M.; Mamat, C.; Belter, B.; Pietzsch, J.

  • Journal of Cellular Biotechnology 5(2019)1, 27-42
    DOI: 10.3233/JCB-189011
    ISSN: 2352-3689

Radiochemical and radiopharmacological characterization of a 64Cu-labeled α-MSH analog conjugated with different chelators

Gao, F.; Sihver, W.; Bergmann, R.; Walther, M.; Stephan, H.; Belter, B.; Neuber, C.; Haase-Kohn, C.; Bolzati, C.; Pietzsch, J.; Pietzsch, H.-J.

Involved research facilities

  • PET-Center

Fluorescent Mouse Pheochromocytoma Spheroids Expressing Hypoxia-Inducible Factor 2 alpha: Morphologic and Radiopharmacologic Characterization

Seifert, V.; Liers, J.; Kniess, T.; Richter, S.; Bechmann, N.; Feldmann, A.; Bachmann, M.; Eisenhofer, G.; Pietzsch, J.; Ullrich, M.

Facile preparation of radium-doped, functionalized nanoparticles as carriers for targeted alpha therapy

Reissig, F.; Hübner, R.; Steinbach, J.; Pietzsch, H.-J.; Mamat, C.

Carboranyl Analogues of Celecoxib with Potent Cytostatic Activity against Human Melanoma and Colon Cancer Cell Lines

Buzharevski, A.; Paskas, S.; Sárosi, M. B.; Laube, M.; Lönnecke, P.; Neumann, W.; Mijatovic, S.; Maksimovic-Ivanic, D.; Pietzsch, J.; Hey-Hawkins, E.

Fluorine-18 labeling of S100 proteins for small animal positron emission tomography

Laube, M.; Kniess, T.; Neuber, C.; Haase-Kohn, C.; Pietzsch, J.

Involved research facilities

  • PET-Center

Development and radiosynthesis of the first 18F-labeled inhibitor of monocarboxylate transporters (MCTs)

Sadeghzadeh, M.; Moldovan, R.-P.; Fischer, S.; Wenzel, B.; Ludwig, F.-A.; Teodoro, R.; Deuther-Conrad, W.; Jonnalagadda, S.; K. Jonnalagadda, S.; Gudelis, E.; Šačkus, A.; R. Mereddy, V.; R. Drewes, L.; Brust, P.

FDG-PET/MRI in patients with pelvic recurrence of rectal cancer: first clinical experiences

Plodeck, V.; Rahbari, N.; Weitz, J.; Radosa, C.; Laniado, M.; Hoffmann, R.; Zoephel, K.; Beuthien-Baumann, B.; Kotzerke, J.; van den Hoff, J.; Platzek, I.

Involved research facilities

  • PET-Center

Synthesis, Structural Characterization and Photodecarbonylation Study of a Dicarbonyl Ruthenium(II)-Bisquinoline Complex

Kubeil, M.; Joshi, T.; Wood, B. R.; Stephan, H.

Synthesis and preliminary radiopharmacological characterisation of an 11C-labelled azadipeptide nitrile as potential PET tracer for imaging of cysteine cathepsins

Laube, M.; Frizler, M.; Wodtke, R.; Neuber, C.; Belter, B.; Kniess, T.; Bachmann, M.; Gütschow, M.; Pietzsch, J.; Löser, R.

Tarnkappen-Technologie für leuchtende Nanopartikeln

Stephan, H.; Zarschler, K.

  • Open Access Logo GIT Labor-Fachzeitschrift (2019)8, 55-57

Tonic signaling and its effects on lymphopoiesis of CAR-armed hematopoietic stem and progenitor cells

Albert, S.; Koristka, S.; Gerbaulet, A.; Cartellieri, M.; Arndt, C.; Feldmann, A.; Berndt, N.; Loureiro, L.; von Bonin, M.; Ehninger, G.; Eugster, A.; Bonifacio, E.; Bornhäuser, M.; Bachmann, M.; Ehninger, A.

Cerebral perfusion changes in presymptomatic genetic frontotemporal dementia: a GENFI study

Mutsaerts, H. J. M. M.; Mirza, S. S.; Petr, J.; Thomas, D. L.; Cash, D. M.; Bocchetta, M.; de Vita, E.; Metcalfe, A. W.; Shirzadi, Z.; Robertson, A. D.; Carmela Tartaglia, M.; Mitchell, S. B.; Black, S. E.; Freedman, M.; Tang-Wai, D.; Keren, R.; Rogaeva, E.; van Swieten, J.; Laforce, R. J.; Tagliavini, F.; Borroni, B.; Galimberti, D.; Rowe, J. B.; Graff, C.; Frisoni, G. B.; Finger, E.; Sorbi, S.; de Mendonça, A.; Rohrer, J. D.; Macintosh, B. J.; Masellis, M.

Involved research facilities

  • PET-Center

Targeting cyclic nucleotide phosphodiesterase 5 (PDE5) in brain: Toward the development of a PET radioligand labeled with fluorine-18

Wenzel, B.; Liu, J.; Dukic-Stefanovic, S.; Deuther-Conrad, W.; Teodoro, R.; Ludwig, F.-A.; Chezal, J.-M.; Moreau, E.; Brust, P.; Maisonial-Besset, A.

Synthesis, 18F-labelling and radiopharmacological characterisation of the C-terminal 30mer of Clostridium perfringens enterotoxin as a potential claudin-targeting peptide

Löser, R.; Bader, M.; Kuchar, M.; Wodtke, R.; Lenk, J.; Wodtke, J.; Kuhne, K.; Bergmann, R.; Haase-Kohn, C.; Urbanová, M.; Steinbach, J.; Pietzsch, J.

Neoadjuvant radiochemotherapy significantly alters the phenotype of plasmacytoid dendritic cells and 6-sulfo LacNAc+ monocytes in rectal cancer

Wagner, F.; Hölig, U.; Wilczkowski, F.; Sommer, U.; Wehner, R.; Kießler, M.; Jarosch, A.; Plesca, I.; Flecke, K.; Arsova, M.; Tunger, A.; Bogner, A.; Reißfelder, C.; Weitz, J.; Schäkel, K.; Troost, E.; Krause, M.; Folprecht, G.; Bornhäuser, M.; Bachmann, M.; Aust, D.; Baretton, G.; Schmitz, M.

Cathepsin B: Active Site Mapping with Peptidic Substrates and Inhibitors

Schmitz, J.; Gilberg, E.; Löser, R.; Bajorath, J.; Bartz, U.; Gütschow, M.

One-pot Cascade Synthesis of Pyrazole-based Isosteres of Valdecoxib by a [3+2] Cycloaddition/[1,5] Sigmatropic Rearrangement Sequence and Evaluation of their COX Inhibitory Activity

Roscales, S.; Bechmann, N.; Pietzsch, J.; Kniess, T.

Involved research facilities

  • PET-Center

Anti-CAR engineered T cells for epitope-based elimination of autologous CAR T cells

Koristka, S.; Ziller-Walter, P.; Bergmann, R.; Arndt, C.; Feldmann, A.; Kegler, A.; Cartellieri, M.; Ehninger, A.; Ehninger, G.; Bornhäuser, M.; Bachmann, M.

Access to 18F-labelled isoxazoles by Ruthenium-promoted 1,3-dipolar cycloaddition of 4-[18F]fluoro-N-hydroxybenzimidoyl chloride with alkynes.

Roscales, S.; Kniess, T.

Involved research facilities

  • PET-Center

Expression of Glypican-3 is an Independent Prognostic Biomarker in Primary Gastro-Esophageal Adenocarcinoma and Corresponding Serum Exosomes

Rahbari, M.; Pecqueux, M.; Aust, D.; Stephan, H.; Tiebel, O.; Chatzigeorgiou, A.; Tonn, T.; Rao, V.; Ziegler, N.; Greif, H.; Lin, K.; Weitz, J.; Rahbari, N. N.; Kahlert, C.

Prognostic value of SUR in patients with trimodality treatment of locally advanced esophageal carcinoma

Bütof, R.; Hofheinz, F.; Zöphel, K.; Schmollack, J.; Jentsch, C.; Zschaeck, S.; Kotzerke, J.; van den Hoff, J.; Michael Baumann, M.

Involved research facilities

  • PET-Center

Studies towards the development of a PET radiotracer for imaging of the P2Y1 receptors in the brain: synthesis, 18F-labeling and preliminary biological evaluation

Moldovan, R.-P.; Wenzel, B.; Teodoro, R.; Neumann, W.; Dukic-Stefanovic, S.; Deuther-Conrad, W.; Hey-Hawkins, E.; Krügel, U.; Brust, P.

2018

Pretherapeutic FDG–PET total metabolic tumor volume predicts response to induction therapy in pediatric Hodgkin’s lymphoma

Rogasch, J.; Hundsdoerfer, P.; Hofheinz, F.; Wedel, F.; Schatka, I.; Amthauer, H.; Furth, C.

Involved research facilities

  • PET-Center

Evaluation of Brain Nuclear Medicine Imaging Tracers in a Murine Model of Sepsis-Associated Encephalopathy

Szöllősi, D.; Hegedűs, N.; Veres, D. S.; Futó, I.; Horváth, I.; Kovács, N.; Martinecz, B.; Dénes, Á.; Seifert, D.; Bergmann, R.; Lebeda, O.; Varga, Z.; Kaleta, Z.; Szigeti, K.; Máthé, D.

Involved research facilities

  • PET-Center

Immune Monitoring of Cancer Patients Prior to and During CTLA-4 or PD-1/PD-L1 Inhibitor Treatment

Tunger, A.; Kießler, M.; Wehner, R.; Temme, A.; Meier, F.; Bachmann, M.; Schmitz, M.

Multimodal PET/MRI Imaging Results Enable Monitoring the Side Effects of Radiation Therapy.

Kovács, N.; Szigeti, K.; Hegedűs, N.; Horváth, I.; Veres, D. S.; Bachmann, M.; Bergmann, R.; Máthé, D.

In vivo confirmation of altered hepatic glucose metabolism in patients with liver fibrosis/cirrhosis by 18F-FDG PET/CT

Verloh, N.; Einspieler, I.; Utpatel, K.; Menhart, K.; Brunner, S.; Hofheinz, F.; van den Hoff, J.; Wiggermann, P.; Evert, M.; Stroszczynski, C.; Hellwig, D.; Grosse, J.

Involved research facilities

  • PET-Center

Synthesis, Receptor Affinity, and Antiallodynic Activity of Spirocyclic σ Receptor Ligands with Exocyclic Amino Moiety

Bergkemper, M.; Kronenberg, E.; Thum, S.; Börgel, F.; Daniliuc, C.; Schepmann, D.; Nieto, F. R.; Brust, P.; Reinoso, R. F.; Alvarez, I.; Wünsch, B.

Diverse Effects of Phospholipase A2 Receptor Expression on LNCaP and PC-3 Prostate Cancer Cell Growth in vitro and in vivo

Friedemann, M.; Nacke, B.; Hagelgans, A.; Jandeck, C.; Bechmann, N.; Ullrich, M.; Belter, B.; Neuber, C.; Sukocheva, O.; Pietzsch, J.; Menschikowski, M.

Towards Utilising Photocrosslinking of Polydiacetylenes for the Preparation of “Stealth” Upconverting Nanoparticles

Nsubuga, A.; Zarschler, K.; Sgarzi, M.; Graham, B.; Stephan, H.; Joshi, T.

Improved Conjugation, 64-Cu Radiolabeling, in Vivo Stability, and Imaging Using Nonprotected Bifunctional Macrocyclic Ligands: Bis(Phosphinate) Cyclam (BPC) Chelators

David, T.; Hlinová, V.; Kubíček, V.; Bergmann, R.; Striese, F.; Berndt, N.; Szöllösi, D.; Hegedus, N.; Mathe, D.; Bachmann, M.; Pietzsch, H.-J.; Hermann, P.

Involved research facilities

  • PET-Center

Fourier Analysis of Cerebral Metabolism of Glucose: Gender Differences in Mechanisms of Color Processing in the Ventral and Dorsal Streams in Mice

Njemanze, P. C.; Kranz, M.; Brust, P.

NMR-based investigations of acyl-functionalized piperazines concerning their conformational behavior in solution

Steinberg, J.; Köckerling, M.; Wodtke, R.; Löser, R.; Mamat, C.

Synthesis, characterization and initial biological evaluation of [⁹⁹ᵐTc]Tc-tricarbonyl labeled DPA-α-MSH peptide derivatives for potential melanoma imaging

Gao, F.; Sihver, W.; Bergmann, R.; Belter, B.; Bolzati, C.; Salvarese, N.; Steinbach, J.; Pietzsch, J.; Pietzsch, H.-J.

Involved research facilities

  • PET-Center

Exploring pitfalls of 64Cu‑labeled EGFR‑targeting peptide GE11 as a potential PET tracer

Striese, F.; Sihver, W.; Gao, F.; Bergmann, R.; Walther, M.; Pietzsch, J.; Steinbach, J.; Pietzsch, H.-J.

Involved research facilities

  • PET-Center

Development of a novel target module redirecting UniCAR T cells to Sialyl Tn-expressing tumor cells

Loureiro, L.; Feldmann, A.; Bergmann, R.; Koristka, S.; Berndt, N.; Arndt, C.; Pietzsch, J.; Novo, C.; Videira, P.; Bachmann, M.

Strain-specific metastatic phenotypes in pheochromocytoma allograft mice

Ullrich, M.; Liers, J.; Peitzsch, M.; Feldmann, A.; Bergmann, R.; Sommer, U.; Richter, S.; Bornstein, S. R.; Bachmann, M.; Eisenhofer, G.; Ziegler, C. G.; Pietzsch, J.

Involved research facilities

  • PET-Center

Development of a selective and highly sensitive fluorescence assay for nucleoside triphosphate diphosphohydrolase1 (NTPDase1, CD39)

Lee, S.-Y.; Luo, X.; Namasivayam, V.; Geiss, J.; Mirza, S.; Pelletier, J.; Stephan, H.; Sevigny, J.; Müller, C. E.

Cerebrovascular Reactivity during Prolonged Breath-Hold in Experienced Freedivers

Keil, V.; Eichhorn, L.; Mutsaerts, H.; Träber, F.; Block, W.; Mädler, B.; van de Ven, K.; Siero, J.; Macintosh, B.; Petr, J.; Fimmers, R.; Schild, H.; Hattingen, E.

Involved research facilities

  • PET-Center

Contilisant, a Tetratarget Small Molecule for Alzheimer’s Disease Therapy Combining Cholinesterase, Monoamine Oxidase Inhibition and H3R Antagonism with Sigma 1R Agonism Profile

Bautista-Aguilera, O. M.; Budni, J.; Mina, F.; Medeiros, E. B.; Deuther-Conrad, W.; Entrena, J. M.; Moraleda, I.; Iriepa, I.; López-Muñoz, F.; Marco-Contelles, J.

From mono- to bivalent: improving theranostic properties of target modules for redirection of UniCAR T cells against EGFR-expressing tumor cells in vitro and in vivo

Albert, S.; Arndt, C.; Koristka, S.; Berndt, N.; Bergmann, R.; Feldmann, A.; Schmitz, M.; Pietzsch, J.; Steinbach, J.; Bachmann, M.

Cognitive correlates of α4β2 nicotinic acetylcholine receptors in mild Alzheimer's dementia

Sabri, O.; Meyer, P. M.; Gräf, S.; Hesse, S.; Wilke, S.; Becker, G.-A.; Rullmann, M.; Patt, M.; Luthardt, J.; Wagenknecht, G.; Hoepping, A.; Smits, R.; Franke, A.; Sattler, B.; Tiepolt, S.; Fischer, S.; Deuther-Conrad, W.; Hegerl, U.; Barthel, H.; Schönknecht, P.; Brust, P.

Radiosynthesis and in vivo evaluation of a fluorine-18 labeled pyrazine based radioligand for PET imaging of the adenosine A2B receptor

Lindemann, M.; Hinz, S.; Deuther-Conrad, W.; Namasivayam, V.; Dukic-Stefanovic, S.; Teodoro, R.; Toussaint, M.; Kranz, M.; Juhl, C.; Steinbach, J.; Brust, P.; Müller, C. E.; Wenzel, B.

Monitoring scanner calibration using the image derived arterial blood SUV in whole-body FDG-PET

Maus, J.; Hofheinz, F.; Apostolova, I.; Kreissl, M. C.; Kotzerke, J.; van den Hoff, J.

Involved research facilities

  • PET-Center

Related publications

Increased evidence for the prognostic value of late-treatment FDG-PET uptake in non-tumor affected oesophagus in irradiated patients with oesophageal carcinomas

Li, Y.; Hofheinz, F.; Furth, C.; Lili, C.; Hua, W.; Ghadjar, P.; Zschaeck, S.

Involved research facilities

  • PET-Center

Effects of systematic partial volume errors on the computation of mean gray matter cerebral blood flow with Arterial Spin Labeling MRI

Petr, J.; Mutsaerts, H. J. M. M.; de Vita, E.; Steketee, R. M. E.; Smits, M.; Nederveen, A. J.; Hofheinz, F.; van den Hoff, J.; Asllani, I.

Involved research facilities

  • PET-Center

Preyssler-Pope-Jeannin Polyanions [NaP5W30O110]14- and [AgP5W30O110]14-: Synthesis, Structural Characterization, Electrochemistry, Antiproliferative and Antibacterial Activity

Haider, A.; Zarschler, K.; Joshi, S. A.; Smith, R.; Lin, Z.; Mougharbel, A.; Herzog, U.; Müller, C. E.; Stephan, H.; Kortz, U.

Synthesis and radiofluorination of novel fluoren-9-one based derivatives for the imaging of α7 nicotinic acetylcholine receptor with PET

Teodoro, R.; Scheunemann, M.; Wenzel, B.; Peters, D.; Deuther-Conrad, W.; Brust, P.

Involved research facilities

  • PET-Center

Molekulare Bildgebung in der Onkologie mittels Positronen-Emissions-Tomographie

Derlin, T.; Grünwald, V.; Steinbach, J.; Wester, H.-J.; Ross, T. L.

Involved research facilities

  • PET-Center

Harnessing the Coordination Chemistry of 1,4,7-Triazacyclononane for Biomimicry and Radiopharmaceutical Applications

Joshi, T.; Kubeil, M.; Nsubuga, A.; Singh, G.; Gasser, G.; Stephan, H.

Clinical translation and regulatory aspects of CAR/TCR-based adoptive cell therapies-the German Cancer Consortium approach.

Krackhardt, A. M.; Anliker, B.; Hildebrandt, M.; Bachmann, M.; Eichmüller, S. B.; Nettelbeck, D. M.; Renner, M.; Uharek, L.; Willimsky, G.; Schmitt, M.; Wels, W. S.; Schüssler-Lenz, M.

Nε-Acryloyllysine piperazides as irreversible inhibitors of transglutaminase 2 – synthesis, structure-activity relationships and pharmacokinetic profiling

Wodtke, R.; Hauser, C.; Ruiz-Gómez, G.; Jäckel, E.; Bauer, D.; Lohse, M.; Wong, A.; Pufe, J.; Ludwig, F.-A.; Fischer, S.; Hauser, S.; Greif, D.; Pisabarro, M. T.; Pietzsch, J.; Pietsch, M.; Löser, R.

Biodistribution studies of ultrasmall silicon nanoparticles and carbon dots in experimental rats and tumor mice

Licciardello, N.; Hunoldt, S.; Bergmann, R.; Singh, G.; Mamat, C.; Faramus, A.; Ddungu, J. L. Z.; Silvestrini, S.; Maggini, M.; de Cola, L.; Stephan, H.

Involved research facilities

  • PET-Center

Overexpression of receptor tyrosine kinase EphB4 triggers tumor growth and hypoxia in A375 melanoma xenografts: insights from multitracer small animal imaging experiments

Neuber, C.; Belter, B.; Meister, S.; Hofheinz, F.; Bergmann, R.; Pietzsch, H.-J.; Pietzsch, J.

Modified Calix[4]crowns as Molecular Receptors for Barium

Steinberg, J.; Bauer, D.; Reissig, F.; Köckerling, M.; Pietzsch, H.-J.; Mamat, C.

Exploring the Metabolism of (+)-[18F]Flubatine in vitro and in vivo: LC-MS/MS aided Identification of Radiometabolites in a Clinical PET Study

Ludwig, F.-A.; Fischer, S.; Smits, R.; Deuther-Conrad, W.; Hoepping, A.; Tiepolt, S.; Patt, M.; Sabri, O.; Brust, P.

Facile Preparation of Multifunctionalisable ‘Stealth’ Upconverting Nanoparticles for Biomedical Applications

Nsubuga, A.; Sgarzi, M.; Zarschler, K.; Kubeil, M.; Hübner, R.; Steudtner, R.; Graham, B.; Joshi, T.; Stephan, H.

Investigation of an 18F-labelled Imidazopyridotriazine for Molecular Imaging of Cyclic Nucleotide Phosphodiesterase 2A

Schröder, S.; Wenzel, B.; Deuther-Conrad, W.; Teodoro, R.; Kranz, M.; Scheunemann, M.; Egerland, U.; Höfgen, N.; Briel, D.; Steinbach, J.; Brust, P.

Bridging from Brain to Tumor imaging: (S)- and (R)-[18F]Fluspidine for investigation of Sigma-1 Receptors in Tumor-bearing Mice

Kranz, M.; Bergmann, R.; Kniess, T.; Belter, B.; Neuber, C.; Cai, Z.; Deng, G.; Fischer, S.; Steinbach, J.; Zhou, J.; Huang, H.; Brust, P.; Deuther-Conrad, W.; Pietzsch, J.

Involved research facilities

  • PET-Center

Spectroscopic Studies on Photoinduced Reactions of the Anticancer Prodrug, trans,trans,trans-[Pt(N3)2(OH)2(py)2]

Vernooij, R. R.; Joshi, T.; Horbury, M. D.; Graham, B.; Izgorodina, E. I.; Stavros, V. G.; Sadler, P. J.; Spiccia, L.; Wood, B. R.

Causative treatment of acid aspiration induced acute lung injury – recent trends from animal experiments and critical perspective

Gramatté, J.; Pietzsch, J.; Bergmann, R.; Richter, T.

Involved research facilities

  • PET-Center

Engrafting human regulatory T cells with a flexible modular chimeric antigen receptor technology

Koristka, S.; Kegler, A.; Bergmann, R.; Arndt, C.; Feldmann, A.; Albert, S.; Cartellieri, M.; Ehninger, A.; Ehninger, G.; Middeke, J. M.; Bornhäuser, M.; Schmitz, M.; Pietzsch, J.; Akgün, K.; Ziemssen, T.; Steinbach, J.; Bachmann, M. P.

Rapid synthesis of sub-10 nm hexagonal NaYF4-based upconverting nanoparticles using Therminol 66

Hesse, J.; Klier, D. T.; Sgarzi, M.; Nsubuga, A.; Bauer, C.; Grenzer, J.; Hübner, R.; Wislicenus, M.; Joshi, T.; Kumke, M. U.; Stephan, H.

Photon vs. proton radiochemotherapy: effects on brain tissue volume and perfusion

Petr, J.; Platzek, I.; Hofheinz, F.; Mutsaerts, H.; Asllani, I.; van Osch, M.; Seidlitz, A.; Krukowski, P.; Gommlich, A.; Beuthien-Baumann, B.; Jentsch, C.; Maus, J.; Troost, E.; Baumann, M.; Krause, M.; van den Hoff, J.

Involved research facilities

  • PET-Center

Chelation of heavy group 2 (radio)metals by p-tert-butylcalix[4]arene-1,3-crown-6 and logK determination via NMR

Bauer, D.; Gott, M.; Steinbach, J.; Mamat, C.

Evaluation of fluorine-18-labelled alpha1(I)-N-telopeptide analogues as substrate-based radiotracers for PET imaging of melanoma-associated lysyl oxidase

Kuchar, M.; Neuber, C.; Belter, B.; Bergmann, R.; Lenk, J.; Wodtke, R.; Kniess, T.; Steinbach, J.; Pietzsch, J.; Löser, R.

Facile Silylation of Cyclitols using Silyl-bis(triflates)

Topp, A.; Köckerling, M.; Reinke, H.; Miethchen, R.; Mamat, C.

Comparison of arterial spin labeling registration strategies in the multi-center GENetic frontotemporal dementia initiative (GENFI)

Mutsaerts, H. J. M. M.; Petr, J.; Thomas, D. L.; de Vita, E.; Cash, D. M.; van Osch, M. J. P.; Golay, X.; Groot, P. F. C.; Ourselin, S.; van Swieten, J.; Laforce, R.; Tagliavini, F.; Borroni, B.; Galimberti, D.; Rowe, J. B.; Graff, C.; D. Pizzini, F. B.; Finger, E.; Sorbi, S.; Castelo Branco, M.; Rohrer, J. D.; Masellis, M.; Macintosh, B. J.

Involved research facilities

  • PET-Center

A Bayesian Approach for Measurements of Stray Neutrons at Proton Therapy Facilities: Quantifying Neutron Dose Uncertainty

Dommert, M.; Reginatto, M.; Zboril, M.; Fiedler, F.; Helmbrecht, S.; Enghardt, W.; Lutz, B.

Recent Progress using the Staudinger Ligation for Radiolabeling Applications

Mamat, C.; Gott, M.; Steinbach, J.

Involved research facilities

  • PET-Center

Novel Valdecoxib Derivates by Ruthenium-catalyzed 1,3-Dipolar Cycloaddition of Nitrile Oxides with Alkynes - Synthesis and COX-2 Inhibition Affinity.

Roscales, S.; Bechmann, N.; Weiss, D. H.; Köckerling, M.; Pietzsch, J.; Kniess, T.

Involved research facilities

  • PET-Center

Structural and kinetic considerations for the application of the traceless Staudinger ligation to future 18F radiolabeling using XRD and 19F-NMR

Köckerling, M.; Mamat, C.

Involved research facilities

  • PET-Center

2017

Synthesis and Pharmacological Evaluation of Identified and Putative Metabolites of the A₁ Adenosine Receptor Antagonist 8-Cyclopentyl-3-(3-fluoropropyl)-1-propylxanthine (CPFPX)

Holschbach, M. H.; Bier, D.; Sihver, W.; Schulze, A.; Neumaier, B.

Quantification: there is more to worry about than good scanner hardware and reliable calibration

Kotzerke, J.; van den Hoff, J.

Involved research facilities

  • PET-Center

Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment

Mattei, D.; Ivanov, A.; Ferrai, C.; Jordan, P.; Guneykaya, D.; Buonfiglioli, A.; Schaafsma, W.; Przanowski, P.; Deuther-Conrad, W.; Brust, P.; Hesse, S.; Patt, M.; Sabri, O.; Ross, T. L.; Eggen, B. J. L.; Bodecke, E. W. G. M.; Kaminska, B.; Beule, D.; Pombo, A.; Kettenmann, H.; Wolf, S. A.

An orthotopic xenograft model for high-risk non-muscle invasive bladder cancer in mice: influence of mouse strain, tumor cell count, dwell time and bladder pretreatment

Huebner, D.; Rieger, C.; Bergmann, R.; Ullrich, M.; Meister, S.; Toma, M.; Wiedemuth, R.; Temme, A.; Novotny, V.; Wirth, M. P.; Bachmann, M.; Pietzsch, J.; Fuessel, S.

Involved research facilities

  • PET-Center

Nitric oxide-releasing selective cyclooxygenase-2 inhibitors as promising radiosensitizers in melanoma cells in vitro

Bechmann, N.; Hauser, S.; Hofheinz, F.; Kniess, T.; Pietzsch, J.

Involved research facilities

  • PET-Center
  • Open Access Logo Annals of Radiation Therapy and Oncology 1(2017)2, 1010

Potential of asphericity as a novel diagnostic parameter in the evaluation of patients with Ga-68-PSMA-HBED-CC PET-positive prostate cancer lesions

Meissner, S.; Janssen, J.; Prasad, V.; Brenner, W.; Diederichs, G.; Hamm, B.; Hofheinz, F.; Makowski, M.

Involved research facilities

  • PET-Center

Exploratory investigation of PSCA-protein expression in primary breast cancer patients reveals a link to HER2/neu overexpression.

Link, T.; Kuithan, F.; Ehninger, A.; Kuhlmann, J. D.; Kramer, M.; Werner, A.; Gatzweiler, A.; Richter, B.; Ehninger, G.; Baretton, G.; Bachmann, M.; Wimberger, P.; Friedrich, K.

Mass spectrometry-based identification of a naturally presented receptor tyrosine kinase-like orphan receptor 1-derived epitope recognized by CD8+ cytotoxic T cells

Heidenreich, F.; Rücker-Braun, E.; Walz, J. S.; Eugster, A.; Kühn, D.; Dietz, S.; Nelde, A.; Tunger, A.; Wehner, R.; Link, C. S.; Middeke, J. M.; Stölzel, F.; Tonn, T.; Stevanovic, S.; Rammensee, H. G.; Bonifacio, E.; Bachmann, M.; Zeis, M.; Ehninger, G.; Bornhäuser, M.; Schetelig, J.; Schmitz, M.

Novel Radiolabeled Bisphosphonates for PET Diagnosis and Endoradiotherapy of Bone Metastases

Pfannkuchen, N.; Meckel, M.; Bergmann, R.; Bachmann, M.; Bal, C.; Sathekge, M.; Mohnike, W.; Baum, R. P.; Rösch, F.

Biological characterization of novel nitroimidazole-peptide conjugates in vitro and in vivo.

Bergmann, R.; Splith, K.; Pietzsch, J.; Bachmann, M.; Neundorf, I.

Characterization of a switchable chimeric antigen receptor platform in a pre-clinical solid tumor model

Bejestani, E. P.; Cartellieri, M.; Bergmann, R.; Ehninger, A.; Loff, S.; Kramer, M.; Spehr, J.; Dietrich, A.; Feldmann, A.; Albert, S.; Wermke, M.; Baumann, M.; Krause, M.; Bornhäuser, M.; Ehninger, G.; Bachmann, M.; von Bonin, M.

Retargeting of UniCAR T cells with an in vivo synthesized target module directed against CD19 positive tumor cells

Bachmann, D.; Aliperta, R.; Bergmann, R.; Feldmann, A.; Koristka, S.; Arndt, C.; Loff, S.; Welzel, P. B.; Albert, S.; Kegler, A.; Ehninger, A.; Cartellieri, M.; Ehninger, G.; Bornhäuser, M.; von Bonin, M.; Werner, C.; Pietzsch, J.; Steinbach, J.; Bachmann, M.

Preparation of 18F-labeled building blocks for peptide conjugation using the "minimalist" approach

Omrane, M. A.; Zlatopolskiy, B. D.; Urusova, E.; Mamat, C.; Feni, L.; Neundorf, I.; Neumaier, B.

  • Poster
    22nd International Symposium on Radiopharmaceutical Sciences (ISRS 2017), Dresden, 14.-19.05.2017, Dresden, Deutschland
  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 60(2017)S1, S261
    DOI: 10.1002/jlcr.3508
    Cited 3 times in Scopus

Evaluation of Ba/Ra Polyoxopalladates for Radiopharmaceutical Applications

Gott, M.; Yang, P.; Kortz, U.; Pietzsch, H.-J.; Steinbach, J.; Mamat, C.

  • Poster
    22nd International Symposium on Radiopharmaceutical Sciences (ISRS 2017), Dresden, 14.-19.05.2017, Dresden, Deutschland
  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 60(2017)S1, S559
    DOI: 10.1002/jlcr.3508
    Cited 3 times in Scopus

Novel Functionalized Calixarenes as Host Molecules for Complexation with Alkaline Earth Metals

Steinberg, J.; Gott, M.; Pietzsch, H.-J.; Steinbach, J.; Mamat, C.

  • Poster
    22nd International Symposium on Radiopharmaceutical Sciences (ISRS 2017), Dresden, 14.-19.05.2017, Dresden, Deutschland
  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 60(2017)S1, S488
    DOI: 10.1002/jlcr.3508
    Cited 3 times in Scopus

Detection of Auger Electron Induced Strand Breaks on Plasmid DNA Caused by Technetium-99m Labeled Pyrene Derivatives

Wunderlich, G.; Reissig, F.; Mamat, C.; Pietzsch, H.-J.; Kotzerke, J.; Steinbach, J.

  • Poster
    22nd International Symposium on Radiopharmaceutical Sciences (ISRS 2017), Dresden, 14.-19.05.2017, Dresden, Deutschland
  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 60(2017)S1, S365
    DOI: 10.1002/jlcr.3508
    Cited 3 times in Scopus

Development of novel target modules for retargeting of UniCAR T cells to GD2 positive tumor cells

Mitwasi, N.; Feldmann, A.; Bergmann, R.; Berndt, N.; Arndt, C.; Koristka, S.; Kegler, A.; Jureczek, J.; Hoffmann, A.; Ehninger, A.; Cartellieri, M.; Albert, S.; Rössig, C.; Ehninger, G.; Pietzsch, J.; Steinbach, J.; Bachmann, M.

Synthesis and X-ray Crystal Structure of N’-Cyano-N,N’-dimethyl-4-nitrobenzohydrazide

Löser, R.; Pitzschler, R.; Köckerling, M.

Individualized risk assessment in neuroblastoma: does the tumoral metabolic activity on 123I-MIBG SPECT predict the outcome?

Rogasch, J.; Hundsdoerfer, P.; Furth, C.; Wedel, F.; Hofheinz, F.; Krüger, P.; Lode, H.; Brenner, W.; Eggert, A.; Amthauer, H.; Schatka, I.

Involved research facilities

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Increased FDG uptake on late-treatment PET in non-tumour-affected oesophagus is prognostic for pathological complete response and disease recurrence in patients undergoing neoadjuvant radiochemotherapy

Zschaeck, S.; Hofheinz, F.; Zöphel, K.; Bütof, R.; Jentsch, C.; Schmollack, J.; Löck, S.; Kotzerke, J.; Baretton, G.; Weitz, J.; Baumann, M.; Krause, M.

Involved research facilities

  • PET-Center

PET Imaging Evaluation of Four sigma1 Radiotracers in Nonhuman Primates

Baum, E.; Cai, Z.; Bois, F.; Holden, D.; Lin, S.-F.; Lara-Jaime, T.; Kapinos, M.; Chen, Y.; Deuther-Conrad, W.; Fischer, S.; Dukic-Stefanovic, S.; Bunse, P.; Wünsch, B.; Brust, P.; Jia, H.; Huang, Y.

1‑(4‑[18F]Fluorobenzyl)-4-[(tetrahydrofuran-2-yl)methyl]piperazine: A Novel Suitable Radioligand with Low Lipophilicity for Imaging σ1 Receptors in the Brain

He, Y.; Xie, F.; Ye, J.; Deuther-Conrad, W.; Cui, B.; Wang, L.; Lu, J.; Steinbach, J.; Brust, P.; Huang, Y.; Lu, J.; Jia, H.

18F-Labeled indole-based analogs as highly selective radioligands for imaging sigma-2 receptors in the brain

Wang, L.; Ye, J.; He, Y.; Deuther-Conrad, W.; Zhang, J.; Zhang, X.; Cui, M.; Steinbach, J.; Huang, Y.; Brust, P.; Jia, H.

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