Publications of Institute of Radiopharmaceutical Cancer Research

903 Publications

2013

An automatic method for accurate volume delineation of heterogeneous tumors in PET
Hofheinz, F.; Langner, J.; Petr, J.; Beuthien-Baumann, B.; Steinbach, J.; Kotzerke, J.; van den Hoff, J.;

Radionuclide impurities in [F-18]F- and [F-18]FDG for positron emission tomography
Koehler, M.; Degering, D.; Zessin, J.; Fuechtner, F.; Konheiser, J.;

High-yield production of functional soluble single-domain antibodies in the cytoplasm of Escherichia coli
Zarschler, K.; Witecy, S.; Kapplusch, F.; Foerster, C.; Stephan, H.;

Synthesis, Characterization, and Metabolism Studies of Fluspidine Enantiomers
Holl, K.; Falck, E.; Köhler, J.; Schepmann, D.; Humpf, H.-U.; Brust, P.; Wünsch, B.;

Synthesis and radiopharmacological evaluation of 64Cu-labeled bombesin analogs featuring a bis(2-pyridylmethyl) 1,4,7-triazacyclononane chelator
Bergmann, R.; Ruffani, A.; Graham, B.; Spiccia, L.; Steinbach, J.; Pietzsch, J.; Stephan, H.;

Design, synthesis, characterisation and in vitro studies of hydrophilic, colloidally stable, 64Cu(II)-labelled, ultra-small iron oxide nanoparticles in a range of human cell lines
Pombo Garcia, K.; Zarschler, K.; Barreto, J. A.; Hesse, J.; Spiccia, L.; Graham, B.; Stephan, H.;

Tissue transglutaminase: an emerging target for therapy and imaging
Pietsch, M.; Wodtke, R.; Pietzsch, J.; Löser, R.;

Radiofluorination and biological evaluation of N-aryl-oxadiazolyl-propionamides as potential radioligands for PET imaging of cannabinoid CB2 receptors
Teodoro, R.; Moldovan, R.-P.; Lueg, C.; Günther, R.; Donat, C. K.; Ludwig, F.-A.; Fischer, S.; Deuther-Conrad, W.; Wünsch, B.; Brust, P.;

In vivo comparison of DOTA based 68Ga-labelled bisphosphonates for bone imaging in non-tumour models
Meckel, M.; Fellner, M.; Thieme, N.; Bergmann, R.; Kubicek, V.; Rösch, F.;

Synthesis and radiopharmacological evaluation of a high-affinity and metabolically stabilized 18F-labeled bombesin analogue for molecular imaging of gastrin-releasing peptide receptor-expressing prostate cancer
Richter, S.; Wuest, M.; Krieger, S. S.; Rogers, B. E.; Friebe, M.; Bergmann, R.; Wuest, F.;

Quantitative Structure Property Relationship of logP for Radiopharmaceutical Technetium and Rhenium Complexes by using Molecular Dynamics Calculations
Yoshizuka, K.; Pietzsch, H.-J.; Seifert, S.; Stephan, H.;
  • Open Access LogoSolvent Extraction Research and Development 20(2013), 15-27

Dynamic behavior of selected PET tracers in embryonated chicken eggs
Gebhardt, P.; Würbach, L.; Heidrich, A.; Heinrich, L.; Walther, M.; Opfermann, T.; Sørensen, B.; Saluz, H. P.;

Fully automated radiosynthesis of both enantiomers of [18F]Flubatine under GMP conditions for human application
Patt, M.; Schildan, A.; Habermann, B.; Fischer, S.; Hiller, A.; Deuther-Conrad, W.; Wilke, S.; Smits, R.; Hoepping, A.; Wagenknecht, G.; Steinbach, J.; Brust, P.; Sabri, O.;

Recent Trends in Bioorthogonal Click-Radiolabeling Reactions Using Fluorine-18
Pretze, M.; Pietzsch, D.; Mamat, C.;

Radiosynthesis and in vivo Evaluation of a 18F-Labelled Styryl-Benzoxazole Derivative for ß-Amyloid Targeting
Ribeiro Morais, G.; Kniess, T.; Bergmann, R.; Gano, L.; Abrunhosa, A.; Santos, I.; Paulo, A.;

Optimization of Pentadentate Bispidines as Bifunctional Chelators for 64Cu Positron Emission Tomography (PET)
Comba, P.; Hunoldt, S.; Morgen, M.; Pietzsch, J.; Stephan, H.; Wadepohl, H.;

Effects of dopaminergic treatment on striatal dopamine turnover in de novo Parkinson disease
Storch, A.; Wolz, M.; Beuthien-Baumann, B.; Loehle, M.; Herting, B.; Schwanebeck, U.; Oehme, L.; van den Hoff, J.; Perick, M.; Graehlert, X.; Kotzerke, J.; Reichmann, H.;

The computation of lipophilicities of 64Cu PET systems based on a novel approach for fluctuating charges
Comba, P.; Martin, B.; Sanyal, A.; Stephan, H.;

Condensation of the dianion of ethyl acetoacetate with perfluoroalkyl iodides. Application to the synthesis of 3-perfluoroalkylsalicylic acids
Mamat, C.; Langer, P.;

Automated preparation of [18F]AFP and [18F]BFP: Two novel bifunctional 18F-labeling building blocks for Huisgen-click
Pretze, M.; Mamat, C.;

An Efficient Bioorthogonal Strategy Using CuAAC Click Chemistry for Radiofluorinations of SNEW Peptides and the Role of Copper Depletion
Pretze, M.; Kuchar, M.; Bergmann, R.; Steinbach, J.; Pietzsch, J.; Mamat, C.;

Design and Development of 99mTc-‘4 + 1’-Labeled Dextran-Mannose Derivatives as Potential Radiopharmaceuticals for Sentinel Lymph Node Detection
Giglio, J.; Fernandez, S.; Jentschel, C.; Pietzsch, H.-J.; Papadopoulos, M.; Pelecanou, M.; Pirmettis, I.; Paolino, A.; Rey, A.;

The PET-derived tumor-to-blood standard uptake ratio (SUR) is superior to tumor SUV as a surrogate parameter of the metabolic rate of FDG
van den Hoff, J.; Oehme, L.; Schramm, G.; Langner, J.; Lougovski, A.; Petr, P.; Beuthien-Baumann, B.; Hofheinz, F.;

Synthesis and radiopharmacological characterisation of a fluorine-18 labelled azadipeptide nitrile as potential PET Tracer for in vivo imaging of cysteine cathepsins
Löser, R.; Bergmann, R.; Frizler, M.; Mosch, B.; Dombrowski, L.; Kuchar, M.; Steinbach, J.; Gütschow, M.; Pietzsch, J.;

Use of 3-[18F]fluoropropanesulfonyl chloride as prosthetic agent for the radiolabelling of amines: Investigation of precursor molecules, labelling conditions and enzymatic stability of the corresponding sulfonamides
Löser, R.; Fischer, S.; Hiller, A.; Köckerling, M.; Funke, U.; Maisonial, A.; Brust, P.; Steinbach, J.;

Recent trends in malignant melanoma biomarker research
Pietzsch, J.; Tandler, N.; Mosch, B.;
  • Clinical Laboratory International 37(2013), 6-8

4-[18F]Fluoro-N-methyl-N-(propyl-2-yn-1-yl)benzenesulfonamide ([18F]F-SA): a versatile building block for labeling of peptides, proteins and oligonucleotides with fluorine-18 via Cu(I)-mediated click chemistry
Ramenda, T.; Steinbach, J.; Wuest, F.;

Dual time point based quantification of metabolic uptake rates in 18F-FDG PET
van den Hoff, J.; Hofheinz, F.; Oehme, L.; Schramm, G.; Langner, J.; Beuthien-Baumann, B.; Steinbach, J.; Kotzerke, J.;

Anti-tumor effects of peptide analogues targeting neuropeptide hormone receptors on mouse pheochromocytoma cells
Ziegler, C. G.; Eisenhofer, G.; Schally, A. V.; Gebauer, L.; Gondek, K.; Ullrich, M.; Qin, N.; Bergmann, R.; Pietzsch, J.; Ehrhart-Bornstein, M.; Bornstein, S. R.;

Synthesis and Evaluation of Novel 18F-Labeled Spirocyclic Piperidine Derivatives as σ1 Receptor Ligands for Positron Emission Tomography Imaging
Li, Y.; Wang, X.; Zhang, J.; Deuther-Conrad, W.; Xie, F.; Zhang, X.; Liu, J.; Qiao, J.; Cui, M.; Steinbach, J.; Brust, P.; Liu, B.; Jia, H.;

Dendrimers as Nb3+ ligands: effect of generation on the efficiency of the sensitized lanthanide emission
Pillai, Z. S.; Ceroni, P.; Kubeil, M.; Heldt, J.-M.; Stephan, H.; Bergamini, G.;

Radiolabeled COX-2 inhibitors for non-invasive visualization of COX-2 expression and activity - a critical update
Laube, M.; Kniess, T.; Pietzsch, J.;

Ga-68- and Cu-64-Labeled NOTA-Albumin Conjugates for PET Sentinel Lymph Node Imaging
Schiller, E.; Bergmann, R.; Wunderlich, G.; Andreeff, M.; Jacob, A.; Pietzsch, H.-J.;

A fluoro versus a nitro derivative - a high-performance liquid chromatography study of two basic analytes with different RP and silica phases as basis for the separation of a positron emission tomography radiotracer
Wenzel, B.; Günther, R.; Brust, P.; Steinbach, J.;

Synthesis of Short and Versatile Heterobifunctional Linkers for Conjugation Purposes of Bioactive Molecules with (Radio-)Labels
Heldt, J.-M.; Kerzendörfer, O.; Mamat, C.; Starke, F.; Pietzsch, H.-J.; Steinbach, J.;

Experimental hypoxia does not influence gene expression and protein synthesis of Eph receptors and ephrin ligands in human melanoma cells in vitro.
Reissenweber, B.; Mosch, B.; Pietzsch, J.;

Inactivation of HNSCC Cells by 90Y-Labeled Cetuximab Strictly Depends on the Number of Induced DNA Double-Strand Breaks
Saker, J.; Kriegs, M.; Zenker, M.; Heldt, J.-M.; Eke, I.; Pietzsch, H.-J.; Grénman, R.; Cordes, N.; Petersen, C.; Baumann, M.; Steinbach, J.; Dikomey, E.; Kasten-Pisula, U.;

Comments on “Comparative Study With New Accuracy Metrics for Target Volume Contouring in PET Image Guided Radiation Therapy”
van den Hoff, J.; Hofheinz, F.;

Investigations into the synthesis, radiofluorination and conjugation of a new [18F]fluorocyclobutyl prosthetic group and its in vitro stability using a tyrosine model system
Franck, D.; Kniess, T.; Steinbach, J.; Zitzmann-Kolbe, S.; Friebe, M.; Dinkelborg, L. M.; Graham, K.;

Resistance of brain glucose metabolism to thiopental-induced CNS depression in newborn piglets
Bernd, W.; Eiselt, M.; Cumming, P.; Xiong, G.; Hinz, R.; Uthe, S.; Brust, P.; Bauer, R.;

Visualization of cyclooxygenase-2 using a 2,3-diarylsubstituted indole-based inhibitor and confocal laser induced cryofluorescence microscopy at 20 K in melanoma cells in vitro
Tondera, C.; Laube, M.; Wimmer, C.; Kniess, T.; Mosch, B.; Großmann, K.; Pietzsch, J.;

Copper(II) chemistry of the functionalized macrocycle cyclam tetrapropionic acid
Comba, P.; Emmerling, F.; Jakob, M.; Kraus, W.; Kubeil, M.; Morgen, M.; Pietzsch, J.; Stephan, H.;

Polyoxometalates as versatile enzyme inhibitors
Stephan, H.; Kubeil, M.; Emmerling, F.; Müller, C. E.;

Radiosynthesis and first evaluation in mice of [18F]NS14490 for molecular imaging of α7 nicotinic acetylcholine receptors
Rötering, S.; Scheunemann, M.; Fischer, S.; Hiller, A.; Peters, D.; Deuther-Conrad, W.; Brust, P.;

Synthesis and biological evaluation of 18F labeled fluoro-oligo-ethoxylated 4-benzylpiperazine derivatives for sigma-1 receptor imaging
Wang, X.; Li, Y.; Deuther-Conrad, W.; Xie, F.; Chen, X.; Cui, M.-C.; Zhang, X.-J.; Zhang, J.-M.; Steinbach, J.; Brust, P.; Liu, B.-L.; Jia, H.-M.;

[68Ga]NS3-RGD and [68Ga] Oxo-DO3A-RGD for imaging αvβ3 integrin expression: synthesis, evaluation, and comparison
Knetsch, P. A.; Petrik, M.; Rangger, C.; Seidel, G.; Pietzsch, H.-J.; Virgolini, I.; Decristoforo, C.; Haubner, R.;

Leitlinie für die Hirnperfusions-SPECT mit Tc-99m Radiopharmaka / Hirnperfusions-SPECT with 99mTc-labelled Radiopharmaceuticals DGN-Guidance (S1 Guideline)
Kranert, T.; Menzel, C.; Bartenstein, P.; Brust, P.; Coenen, H. H.; Krause, B. J.; Kuwert, T.; Sabri, O.; Schreckenberger, M.; Tatsch, K.; Grünwald, F.;

2-Carbaborane-3-phenyl-1H-indoles—Synthesis via McMurry Reaction and Cyclooxygenase (COX) Inhibition Activity
Laube, M.; Neumann, W.; Scholz, M.; Lönnecke, P.; Crews, B.; Marnett, L. J.; Pietzsch, J.; Kniess, T.; Hey-Hawkins, E.;

Impact of 5-lipoxygenase inhibitors on the spatiotemporal distribution of inflammatory cells and neuronal COX-2 expression following experimental traumatic brain injury in rats
Härtig, W.; Michalski, D.; Seeger, G.; Voigt, C.; Donat, C. K.; Dulin, J.; Kacza, J.; Meixensberger, J.; Arendt, T.; Schuhmann, M. U.;

Radiosynthesis of racemic and enantiomerically pure (–)-[18F]flubatine – A promising PET radiotracer for neuroimaging of α4β2 nicotinic acetylcholine receptors
Fischer, S.; Hiller, A.; Smits, R.; Hoepping, A.; Funke, U.; Wenzel, B.; Cumming, P.; Sabri, O.; Steinbach, J.; Brust, P.;

PET/MR for therapy response evaluation in malignant lymphoma: initial experience
Platzek, I.; Beuthien-Baumann, B.; Langner, J.; Popp, M.; Schramm, G.; Ordemann, R.; Laniado, M.; Kotzerke, J.; van den Hoff, J.;

PET/MR in head and neck cancer: initial experience
Platzek, I.; Beuthien-Baumann, B.; Schneider, M.; Gudziol, V.; Langner, J.; Schramm, G.; Laniado, M.; Kotzerke, J.; van den Hoff, J.;

Partial volume correction in arterial spin labeling using a Look-Locker sequence
Petr, J.; Schramm, G.; Hofheinz, F.; Langner, J.; Steinbach, J.; van den Hoff, J.;

High specific activity 61Cu via 64Zn(p,α)61Cu reaction at low proton energies
Thieme, S.; Walther, M.; Preusche, S.; Rajander, J.; Pietzsch, H.-J.; Solin, O.; Steinbach, J.;

Quantitative accuracy of attenuation correction in the Philips Ingenuity TF whole-body PET/MR system A direct comparison with transmission-based attenuation correction
Schramm, G.; Langner, J.; Hofheinz, F.; Petr, J.; Beuthien-Baumann, B.; Platzek, I.; Steinbach, J.; Kotzerke, J.; van den Hoff, J.;

Use of targeted therapy for refractory ALK-positive anaplastic large cell lymphoma as a bridging strategy prior to allogeneic transplantation
Ordemann, R.; Stöhlmacher, J.; Beuthien-Baumann, B.; Platzek, I.; van den Hoff, J.; Kroschinsky, F.; Middeke, J. M.; Platzbecker, U.; Zietz, C.; Bornhäuser, M.; Ehninger, G.;

Design, synthesis, and preliminary in vitro and in vivo pharmacological evaluation of 4-{4-[2-(4-(2-substitutedquinoxalin-3-yl)piperazin-1-yl)ethyl]phenyl}thiazoles as atypical antipsychotic agents
Chandra Sekhar, K. V. G.; Rao, V. S.; Deuther-Conrad, W.; Sridhar, D.; Nagesh, H. N.; Kumar, V. S.; Brust, P.; Kumar, M. M. K.;

2012

Cerebral blood flow quantification in the rat: a direct comparison of arterial spin labeling MRI with radioactive microsphere PET
Bos, A.; Bergmann, R.; Strobel, K.; Hofheinz, F.; Steinbach, J.; van den Hoff, J.;

Feasibility of estimation of brain volume and 2-deoxy-2-F-18-fluoro-D-glucose metabolism using a novel automated image analysis method: Application in Alzheimer's disease
Musiek, E. S.; Saboury, B.; Mishra, S.; Chen, Y.; Reddin, J. S.; Newberg, A. B.; Udupa, J. K.; Detre, J. A.; Hofheinz, F.; Torigian, D.; Alavi, A.;
  • Hellenic Journal of Nuclear Medicine 15(2012), 190-196

Exploratory prospective trial of hypoxia-specific PET imaging during radiochemotherapy in patients with locally advanced head-and-neck cancer
Zips, D.; Zöphel, K.; Abolmaali, N.; Perrin, R.; Abramyuk, A.; Haase, R.; Appold, S.; Steinbach, J.; Kotzerke, J.; Baumann, M.;

Flow cytometric cell-based assay to preselect antibody constructs for radionuclide conjugation
Ingargiola, M.; Dittfeld, C.; Runge, R.; Zenker, M.; Heldt, J.-M.; Steinbach, J.; Cordes, N.; Baumann, M.; Kotzerke, J.; Kunz-Schughart, L.;

Synthesis and biological evaluation of a novel Tc-99m cyclopentadienyl tricarbonyl complex ([(Cp-R)Tc-99m(CO)(3)]) for sigma-2 receptor tumor imaging
Chen, X.; Cui, M. C.; Deuther-Conrad, W.; Tu, Y. F.; Ma, T.; Xie, Y.; Jia, B.; Li, Y.; Xie, F.; Wang, X.; Steinbach, J.; Brust, P.; Liu, B. L.; Jia, H. M.;

Protein and non-protein biomarkers in melanoma: a critical update.
Tandler, N.; Mosch, B.; Pietzsch, J.;

Functional arterial spin labeling: Optimal sequence duration for motor activation mapping in clinical practice
Raoult, H.; Ferré, J.-C.; Petr, J.; Bannier, E.; Stamm, A.; Barillot, C.; Gauvrit, J.-Y.;

Synthesis, in silico, in vitro, and in vivo investigation of 5-[11C]methoxy-substituted sunitinib, a tyrosine kinase inhibitor of VEGFR-2
Caballero, J.; Muñoz, C.; Alzate-Morales, J. H.; Cunha, S.; Gano, L.; Bergmann, R.; Steinbach, J.; Kniess, T.;

Cellular and molecular properties of 90Y-labeled cetuximab in combination with radiotherapy on human tumor cells in vitro
Saki, M.; Toulany, M.; Sihver, W.; Zenker, M.; Heldt, J.-M.; Mosch, B.; Pietzsch, H.-J.; Baumann, M.; Steinbach, J.; Rodemann, H. P.;

18F-Labeled phosphopeptide-cell-penetrating peptide dimers with enhanced cell uptake properties in human cancer cells
Richter, S.; Bouvet, V.; Wuest, M.; Bergmann, R.; Steinbach, J.; Pietzsch, J.; Neundorf, I.; Wuest, F.;

Synthesis and cytotoxicity of pyridine and quinoline oxorhenium(V) complexes with tridentate (NS2, S-3)/monodentate (s) coordination
Segal, I.; Zablotskaya, A.; Kniess, T.; Shestakova, I.;

18F-labelled CCR1-receptor antagonist is not suitable for imaging of Alzheimer's disease
Beuthien-Baumann, B.; Holthoff, V.; Mäding, P.; Bergmann, R.; Pawelke, B.; Holl, G.; von Kummer, R.; Kotzerke, J.; van den Hoff, J.;

Cannabinoid Receptor Type 2 (CB2) Selective N-Aryl-oxadiazolyl-propionamides: Synthesis, Radiolabeling, Molekular Modelling and Biological Evaluation
Rühl, T.; Deuther-Conrad, W.; Fischer, S.; Günther, R.; Hennig, L.; Krautscheid, P.; Brust, P.;

Synthesis and crystal structure of benzyl[(1S)-1-(5-amino-1,3,4-oxadiazol-2-yl)-2-phenylethyl]carbamate
Löser, R.; Nieger, M.; Gütschow, M.;

Combined PET/MR systems: an overview and comparison of currently available options
Herzog, H.; van den Hoff, J.;
  • Quarterly Journal of Nuclear Medicine and Molecular Imaging 56(2012), 247-267

Improved anatomic visualization of a glomus caroticum tumour within the carotic bifurcation with combined 68Ga-DOTATATE PET/MRI
Beuthien-Baumann, B.; Platzek, I.; Lauterbach, I.; van den Hoff, J.; Schramm, G.; Zöphel, K.; Laniado, M.; Kotzerke, J.;

Fluorine-18-Radiolabeling and Radiopharmacological Characterization of a Benzodioxolylpyrimidine as a Radiotracer Targeting the Receptor Tyrosine Kinase EphB4
Mamat, C.; Mosch, B.; Neuber, C.; Köckerling, M.; Bergmann, R.; Pietzsch, J.;

Novel 7α-alkoxy-17α-(4’-halophenylethynyl)estradiols as potential SPECT/PET imaging agents for estrogen receptor expressing tumors: synthesis and binding affinity evaluation
Neto, C.; Oliveira, M. C.; Gano Fernanda Marques, M. L.; Yasuda, T.; Thiemann, T.; Kniess, T.; Santos, I.;

Synthesis and characterization of novel tetrahedral copper(I) complexes comprising tridentate PNP-aminodiphosphines and tetradentate PN(X)P-substituted aminodiphosphines (X = O, S)
Peruzzo, V.; Pretzsch, C.; Tisato, F.; Porchia, M.; Refosco, F.; Marzano, C.; Gandin, V.; Schiller, E.; Walther, M.; Pietzsch, H.-J.;

Synthesis, in vitro and in vivo characterization of novel 99mTc-‘4+1’-labeled 5-nitroimidazole derivatives as potential agents for imaging hypoxia
Giglio, J.; Fernández, S.; Pietzsch, H.-J. D.; Dematteis, S.; Moreno, M.; Pacheco, J. P.; Cerecetto, H.; Rey, A.;

Design, Evaluation, and Comparison of Ghrelin Receptor Agonists and Inverse Agonists as Suitable Radiotracers for PET Imaging
Chollet, C.; Bergmann, R.; Pietzsch, J.; Beck-Sickinger, A. G.;

Irradiation affects cellular properties and Eph receptor expression in human melanoma cells
Mosch, B.; Pietzsch, D.; Pietzsch, J.;

A method for model-free partial volume correction in oncological PET
Hofheinz, F.; Langner, J.; Petr, J.; Beuthien-Baumann, B.; Oehme, L.; Steinbach, J.; Kotzerke, J.; van den Hoff, J.;

Radioiodinated sunitinib as a potential radiotracer for imaging angiogenesis - radiosynthesis and first radiopharmacological evaluation of 5-[125I]Iodo-sunitinib
Kuchar, M.; Oliveira, M. C.; Gano, L.; Santos, I.; Knieß, T.;

Radiohalogenated 4-anilinoquinazoline-based EGFR-TK inhibitors as potential cancer imaging agents
Neto, C.; Fernandes, C.; Oliveira, M. C.; Gano, L.; Mendes, F.; Kniess, T.; Santos, I.;

Ecto-ATPase inhibition: ATP and adenosine release under physiological and ischemic in vivo conditions in the rat striatum
Melani, A.; Corti, F.; Stephan, H.; Müller, C. E.; Donati, C.; Bruni, P.; Vannucchi, M. G.; Pedata, F.;

Study of differences in the VEGFR2 inhibitory activities between semaxanib and SU5205 using 3D-QSAR, docking, and molecular dynamics simulations
Munoza, C.; Adasmea, F.; Alzate-Morales, J. H.; Vergara-Jaquea, A.; Kniess, T.; Caballero, J.;

Radiolabeled small molecule inhibitors of VEGFR – recent advances
Kniess, T.;

Module-assisted preparation of 64Cu with high specific activity
Thieme, S.; Walther, M.; Pietzsch, H.-J.; Henniger, J.; Preusche, S.; Mäding, P.; Steinbach, J.;

SUV-measurements and patient-specific corrections thereof in pediatric Hodgkin-lymphoma: Is there a benefit for PPV in early response assessment by FDG-PET?
Furth, C.; Meseck, R. M.; Steffen, I. G.; Schoenberger, S.; Denecke, T.; Henze, G.; Hautzel, H.; Hofheinz, F.; Großer, O.; Hundsdoerfer, P.; Amthauer, H.; Ruf, J.;

Automatic volume delineation in oncological PET. Evaluation of a dedicated software tool and comparison with manual delineation in clinical data sets
Hofheinz, F.; Pötzsch, C.; Oehme, L.; Beuthien-Baumann, B.; Steinbach, J.; Kotzerke, J.; van den Hoff, J.;

Synthesis and Molecular Structure of tert-Butyl 4-(2-tert-butoxy-2-oxoethyl)piperazine-1-carboxylate
Mamat, C.; Flemming, A.; Köckerling, M.;

The Synthesis and Molecular Structure of 2-(4-Methoxybenzyl)-4-nitro-2H-indazole
Ebert, K.; Köckerling, M.; Mamat, C.;

Specific targeting of hypoxic tumor tissue with nitroimidazole-peptide conjugates
Splith, K.; Bergmann, R.; Pietzsch, J.; Neundorf, I.;

Pyrrolovesamicols - Synthesis, structure and VAChT binding of two 4-fluorobenzoyl regioisomers
Wenzel, B.; Li, Y.; Kraus, W.; Sorger, D.; Sabri, O.; Brust, P.; Steinbach, J.;

The Molecular Structure of 1,2:5,6-Di-O-isopropylidene-3-O-toluenesulfonyl-a-D-glucofuranose
Mamat, C.; Peppel, T.; Köckerling, M.;

Imaging of the brain serotonin transporters (SERT) with 18F-labelled fluoromethyl-McN5652 and PET in humans
Hesse, S.; Brust, P.; Mäding, P.; Becker, G.-A.; Seese, A.; Patt, M.; Sorger, D.; Zessin, J.; Sacher, J.; Lobsien, D.; Habermann, B.; Meyer, P. M.; Füchtner, F.; Luthardt, J.; Bresch, A.; Steinbach, J.; Sabri, O.;

Development of radioligands for α7-nAChR imaging with positron emission tomography
Brust, P.; Peters, D.; Deuther-Conrad, W.;

Synthesis, radiofluorination and pharmacological evaluation of fluoromethyl substituted spirocyclic PET tracers for labeling of σ1 receptors in the central nervous system and comparison with longer homologues
Maisonial, A.; Grosse Maestrup, E.; Wiese, C.; Hiller, A.; Schepmann, D.; Deuther-Conrad, W.; Fischer, S.; Brust, P.; Wünsch, B.;

Radiosynthesis and Radiotracer Properties of a 7-(2-[F-18]Fluoroethoxy)-6-methoxy-pyrrolidinylquinazoline for Imaging of Phosphodiesterase 10A with PET
Funke, U.; Deuther-Conrad, W.; Schwan, G.; Maisonial, A.; Scheunemann, M.; Fischer, S.; Hiller, A.; Briel, D.; Brust, P.;

Site-selective radiolabeling of peptides by 18F-fluorobenzoylation with [18F]SFB in solution and on solid phase - a comparative study
Kuchar, M.; Pretze, M.; Knieß, T.; Steinbach, J.; Pietzsch, J.; Löser, R.;

Effect of leukotriene inhibitors on evolution of experimental brain contusions
Voigt, C. L. M.; Donat, C. K.; Härtig, W.; Förschler, A.; Arendt, T.; Meixensberger, J.; Schuhmann, M. U.;

Radiosynthesis of a 18F-labeled 2,3-diarylsubstituted indole via McMurry coupling for functional characterization of cyclooxygenase-2 (COX-2) in vitro and in vivo
Kniess, T.; Laube, M.; Bergmann, R.; Graf, F.; Steinbach, J.; Wuest, F.; Pietzsch, J.;

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