Publications of Institute of Radiopharmaceutical Cancer Research

40 Publications


Convenient recycling and reuse of bombarded [18O]H2O for the production and the application of [18F]F
Rötering, S.; Franke, K.; Zessin, J.; Brust, P.; Füchtner, F.; Fischer, S.; Steinbach, J.


Radionuclide impurities in [F-18]F- and [F-18]FDG for positron emission tomography
Koehler, M.; Degering, D.; Zessin, J.; Fuechtner, F.; Konheiser, J.


Imaging of the brain serotonin transporters (SERT) with 18F-labelled fluoromethyl-McN5652 and PET in humans
Hesse, S.; Brust, P.; Mäding, P.; Becker, G.-A.; Seese, A.; Patt, M.; Sorger, D.; Zessin, J.; Sacher, J.; Lobsien, D.; Habermann, B.; Meyer, P. M.; Füchtner, F.; Luthardt, J.; Bresch, A.; Steinbach, J.; Sabri, O.


Visualization of the focus in congenital hyperinsulinism by intraoperative sonography
von Rohden, L.; Mohnike, K.; Mau, H.; Eberhard, T.; Mohnike, W.; Blankenstein, O.; Empting, S.; Koch, M.; Fuechtner, F.; Barthlen, W.

Intraoperative Sonography: A Technique for Localizing Focal Forms of Congenital Hyperinsulinism in the Pancreas
von Rohden, L.; Mohnike, K.; Mau, H.; Eberhard, T.; Mohnike, W.; Blankenstein, O.; Empting, S.; Koch, M.; Füchtner, F.; Barthlen, W.


Radiation treatment planning in brain tumours Potential impact of 3-O-methyl-6-[18F]fluoro-L-DOPA and PET
Alheit, H.; Oehme, L.; Winkler, C.; Füchtner, F.; Hoepping, A.; Grabowski, J.; Kotzerke, J.; Beuthien-Baumann, B.

Congenital hyperinsulinism: [18F]DOPA PET/CT scan of a focal lesion in the head of the pancreas
Kapoor, R. R.; Gilbert, C.; Mohnike, K.; Blankenstein, O.; Füchtner, F.; Hussain, K.

Factors affecting the specific activity of [18F]fluoride from a [18O]water target
Füchtner, F.; Preusche, S.; Mäding, P.; Zessin, J.; Steinbach, J.

Evaluation of 18F- L-DOPA PET-CT for surgery in focal congenital hyperinsulinism
Barthlen, W.; Mau, H.; Koch, M.; Höhne, C.; Blankenstein, O.; Mohnike, W.; Eberhard, T.; Füchtner, F.; Lorenz-Depiereux, B.; Mohnike, K.
  • Journal of Clinical Endocrinology and Metabolism 93(2008)3, 869-875

18F-DOPA Positron Emission Tomography for Preoperative Localization in Congenital Hyperinsulinism
Mohnike, K.; Blankenstein, O.; Minn, H.; Mohnike, W.; Füchtner, F.; Otonovski, T.

Aspects of 6-[18F]fluoro-L-DOPA preparation: Deuterochloroform as a substitute solvent for Freon 11
Füchtner, F.; Zessin, J.; Mäding, P.; Wüst, F.


L-Type Amino Acid Transporters LAT1 and LAT4 in Cancer: Uptake of 3-O- Methyl-6-18F-Fluoro-L-Dopa (18F-OMFD) in Human Adenocarcinoma and Squamous Cell Carcinoma in vitro and in vivo
Haase, C.; Bergmann, R.; Füchtner, F.; Hoepping, A.; Pietzsch, J.


Synthesis of a 11C-labelled taxane derivative by [1-11C]acetylation
Mäding, P.; Zessin, J.; Pleiß, U.; Füchtner, F.; Wüst, F.

18F-Labelling of a potent nonpeptide CCR1 antagonist: Synthesis of 1-(5-chloro-2-{2-[(2R)-4-(4-[18F]fluorobenzyl)-2methylpiperazin-1-yl]-2-oxoethoxy}phenyl)urea in an automated module
Mäding, P.; Füchtner, F.; Johannsen, B.; Steinbach, J.; Hilger, C. S.; Friebe, M.; Halks-Miller, M.; Horuk, R.; Mohan, R.
  • Journal of Labelled Compounds and Radiopharmaceuticals 49 (2006) 253-262


Effect of Moderate Hypercapnic Hypoxia on Cerebral Dopaminergic Activity and Brain O2 Uptake in Intrauterine Growth–Restricted Newborn Piglets
Bauer, R.; Walter, B.; Vorwieger, G.; Fritz, A.; Füchtner, F.; Zwiener, U.; Brust, P.

Module-assisted synthesis of the bifunctional labelling agent N-succinimidy 4-[18F]fluorobenzoate ([18F]SFB)
Mäding, P.; Füchtner, F.; Wüst, F.
  • Applied Radiation and Isotopes 63(2005), 329-332


The Influx of Neutral Amino Acids into the Porcine Brain During Development: A Positron Emission Tomography Study
Brust, P.; Vorwieger, G.; Walter, B.; Füchtner, F.; Stark, H.; Kuwabara, H.; Steinbach, J.; Bauer, R.
  • Developmental Brain Research 152(2004), 241-253

3-O-Methyl-6-18F-Fluoro-L-Dopa, a New Tumor Imaging Agent: Investigation of Transport Mechanism In Vitro
Bergmann, R.; Pietzsch, J.; Füchtner, F.; Pawelke, B.; Beuthien-Baumann, B.; Johannsen, B.; Kotzerke, J.
  • Journal of Nuclear Medicine 45(2004), 2116-2122

Developmental changes in the activity of aromatic amino acid decarboxylase and catechol-O-methyl transferase in pigs: a positron emission tomography study
Brust, P.; Walter, B.; Hinz, R.; Füchtner, F.; Müller, M.; Steinbach, J.; Bauer, R.
  • Neuroscience Letters, 364(2004)3, 159-163

Age-dependent effects of severe traumatic brain injury on cerebral dopaminergic activity in newborn and juvenile pigs
Walter, B.; Brust, P.; Füchtner, F.; Müller, M.; Hinz, R.; Kuwabara, H.; Fritz, H.; Zwiener, U.; Bauer, R.
  • Journal of Neurotrauma 21(2004)8, 1076-1089

Changes in brain metabolism associated with remission in unipolar major depression
Holthoff, V.; Beuthien-Baumann, B.; Zündorf, G.; Triemer, A.; Lüdecke, S.; Winiecki, P.; Koch, R.; Füchtner, F.; Herholz, K.
  • Acta Psychiatrica Scandinavica 110(2004), 184-194


Impact of asymmetric intrauterine growth restriction on organ function in newborn piglets
Bauer, R.; Walter, B.; Brust, P.; Füchtner, F.; Zwiener, U.
  • European Journal of Obstetrics and Gynecology and Reproductive Biology 110 (2003) S40-S49

3-O-Methyl-6-[18F]Fluoro-L-DOPA and its Evaluation in Brain Tumour Imaging
Beuthien-Baumann, B.; Bredow, J.; Burchert, W.; Füchtner, F.; Bergmann, R.; Alheit, H.-D.; Reiss, G.; Hliscs, R.; Steinmeier, R.; Franke, W.-G.; Johannsen, B.; Kotzerke, J.
  • European Journal of Nuclear Medicine and Molecular Imaging (2003) 30: 1004-1008

Efficient synthesis of the 18F-labelled amino acid 3-O-methyl-6-[18F]fluoro-L-DOPA
Füchtner, F.; Steinbach, J.
  • Applied Radiation and Isotopes 58 (2003) 575-578


Effect of hypoxia/hypercapnia on metabolism of 6-[18F]fluoro-L-DOPA in newborn piglets
Bauer, R.; Brust, P.; Walter, B.; Vorwieger, G.; Bergmann, R.; Elhalag, E.; Fritz, A.; Steinbach, J.; Füchtner, F.; Hinz, R.; Zwiener, U.; Johannsen, B.
  • Brain Research 934 (2002) 22-33

Distribution of estrone sulfatase in rat brain determined by in vitro autoradiography with 16alpha-[18F]fluoroestradiol-3,17beta-disulfamate
Rodig, H.; Brust, P.; Römer, J.; Kasch, H.; Bergmann, R.; Füchtner, F.; Steinbach, J.; Johannsen, B.
  • Applied Radiation and Isotopes 56 (2002) 773-780

Aspects of 6-[18F]fluoro-L-DOPA preparation: Precursor synthesis, preparative HPLC purification and determination of radiochemical purity
Füchtner, F.; Angelberger, P.; Kvaternik, H.; Hammerschmidt, F.; Peric Simovc, B.; Steinbach, J.
  • Nuclear Medicine and Biology, 29 (2002) 477-481

Distribution of 16alpha-[18F]fluoro-estradiol-3,17beta-disulfamate (FESDS) in rats, tumour-bearing mice and piglets
Brust, P.; Rodig, H.; Römer, J.; Kasch, H.; Bergmann, R.; Füchtner, F.; Zips, D.; Baumann, M.; Steinbach, J.; Johannsen, B.
  • Applied Radiation and Isotopes 57 (2002) 687-695


Simultaneous preparation of 16alpha-[18F]fluoroestradiol-sulphamates in an automated module. A high-yield procedure for 16alpha-[18F]fluoroestradiol-17beta-sulphamate
Römer, J.; Füchtner, F.; Steinbach, J.; Kasch, H.
  • Poster
    14th International Symposium on Radiopharmaceutical Chemistry, Interlaken/Schweiz, 10.-15.06.2001
  • Journal of Labelled Compounds and Radiopharmaceuticals 44 (2001) 689-700

Intrauterine growth restriction induces up-regulation of cerebral aromatic amino acid decarboxylase activity in newborn piglets: [18F]fluorodopa positron-emission-tomographic study
Bauer, R.; Walter, B.; Vorwieger, G.; Bergmann, R.; Füchtner, F.; Brust, P.
  • Pediatric Research 49 (2001) 474-480

Automated Synthesis of 16alpha-[18F]fluoroestradiol-3,17beta-disulphamate
Römer, J.; Füchtner, F.; Steinbach, J.; Kasch, H.
  • Applied Radiation and Isotopes 55 (2001) 631-639.


Synthesis of 16alpha-[18F]fluorestradiol-3,17beta-disulphamate
Römer, J.; Füchtner, F.; Steinbach, J.
  • J. Labelled Cpd. Radiopharm. 43 (2000) 425-436

Relation between brain tissue pO2 and dopamine synthesis of basal ganglia - A 18FDOPA-PET study in newborn piglets
Bauer, R.; Brust, P.; Walter, B.; Vorwieger, G.; Bergmann, R.; Füchtner, F.; Steinbach, J.; El-Hallag, E.; Fritz, A.; Johannsen, B.; Zwiener, U.
  • J. Perinat. Med. 28 (2000) 54-60


The stability of 2-[18F]fluoro-deoxy-D-glucose towards epimerisation under alkaline conditions
Meyer, G. J.; Matzke, K. H.; Hamacher, K.; Füchtner, F.; Steinbach, J.; Notohamiprodjo, G.; Zijlstra, S.
  • Applied Radiation and Isotopes 51 (1999) 37-41

Upregulation of the Aromatic Amino Acid Decarboxylase under Neonatal Asphyxia
Brust, P.; Bauer, R.; Vorieger, G.; Walter, B.; Bergmann, R.; Füchtner, F.; Steinbach, J.; Zwiener, U.; Johannsen, B.
  • Neurobiology of Disease 6, (1999) 131-139

Long-distance transport of radionuclides between PET cyclotron and PET radiochemistry
Preusche, S.; Füchtner, F.; Steinbach, J.; Zessin, J.; Krug, H.; Neumann, W.
  • Appl. Rad. Isot. 51 (1999) 625-630

Automated Production of the PET Tracer 16 alpha-[18F] Fluoroestradiol for Breast Cancer Imaging
Römer, J.; Füchtner, F.; Steinbach, J.; Johannsen, B.
  • Nucl. Med. Biol. 26 (1999) 473-479


Simultaneous Measurement of 18F-FDOPA Metabolism and Cerebral Blood Flow in Newborn Piglets
Brust, P.; Bauer, R.; Walter, B.; Bergmann, R.; Füchtner, F.; Vorwieger, G.; Steinbach, J.; Johannsen, B.; Zwiener, U.
  • Int. J. Devl. Neuroscience, Vol. 16, No. 5, pp 353-364, 1998


Basic Hydrolysis of 2-(18F)Fluoro-1,3,4,6-tetra-0-acetyl-D-glucose in the Preparation of 2-(18F)Fluoro-2-deoxy-D-glucose
Füchtner, F.; Steinbach, J.; Mäding, P.; Johannsen, B.
  • Applied Radiation and Isotopes 47 (1996) 1 pp. 61-66


N.C.A. 11C-labelling of aromatic compounds in the ring-position: synthesis of nitro-[1-11C]benzene and [1-11C]aniline
Steinbach, J.; Mäding, P.; Füchtner, F.; Johannsen, B.
  • Journal of Labelled Compounds and Radiopharmaceuticals 36 (1994) 1 pp. 33