Publications of Institute of Radiopharmaceutical Cancer Research

191 Publications

2024

Alpha-emitting Radionuclides: Current Status and Future Perspectives

Miederer, M.; Benešová-Schäfer, M.; Mamat, C.; Kästner, D.; Pretze, M.; Michler, E.; Brogsitter, C.; Kotzerke, J.; Kopka, K.; Scheinberg, D.; McDevitt, M.

Preparation of HOPO-containing lariate ethers based on the diaza-18-crown-6 scaffold

Paßler, F.; Belke, L.; Reissig, F.; Kopka, K.; Mamat, C.

2023

Equilibrium Thermodynamics of Macropa Complexes with Selected Metal Isotopes of Radiopharmaceutical Interest

Blei, M. K.; Waurick, L.; Reissig, F.; Kopka, K.; Stumpf, T.; Drobot, B.; Kretzschmar, J.; Mamat, C.

Preclinical Characterization of the 177Lu-Labeled Prostate Stem Cell Antigen (PSCA)-Specific Monoclonal Antibody 7F5

Striese, F.; Neuber, C.; Gräßel, S.; Arndt, C.; Ullrich, M.; Steinbach, J.; Pietzsch, J.; Bergmann, R.; Pietzsch, H.-J.; Sihver, W.; Frenz, M.; Feldmann, A.; Bachmann, M.

Involved research facilities

  • PET-Center

Cyclotron-based Production of 67Cu for Radionuclide Theranostics Via the 70Zn(p,α)67Cu Reaction

Brühlmann, S. A.; Walther, M.; Kreller, M.; Reissig, F.; Pietzsch, H.-J.; Knieß, T.; Kopka, K.

The Impact of Nε-Acryloyllysine Piperazides on the Conformational Dynamics of Transglutaminase 2

Heerwig, A.; Kick, A.; Sommerfeld, P.; Eimermacher, S.; Hartung, F.; Laube, M.; Fischer, D.; Pietzsch, H.-J.; Pietzsch, J.; Löser, R.; Mertig, M.; Pietsch, M.; Wodtke, R.

Involved research facilities

  • ZRT

Copper-free click bioconjugation of technetium-99m complexes using strained cyclononyne derivatives

Schlesinger, M.; Jentschel, C.; Pietzsch, H.-J.; Kopka, K.; Mamat, C.

Enzymological characterization of ⁶⁴Cu-labeled neprilysin substrates and their application for modulating the renal clearance of targeted radiopharmaceuticals

Brandt, F.; Ullrich, M.; Wodtke, J.; Kopka, K.; Bachmann, M.; Löser, R.; Pietzsch, J.; Pietzsch, H.-J.; Wodtke, R.

Involved research facilities

  • ZRT

Related publications

Calix[4]crowns with perfluoroalkylsulfonylcarboxamide functions: a complexation approach for heavy group 2 metal ions

Reissig, F.; Bauer, D.; Al-Ameed, K.; Luber, S.; Köckerling, M.; Steinbach, J.; Pietzsch, H.-J.; Mamat, C.

2022

Synthesis and preclinical evaluation of rhenium and technetium-99m “4 + 1” mixed-ligand complexes bearing quinazoline derivatives as potential EGFR imaging agents

Kiritsis, C.; Shegani, A.; Makrypidi, K.; Roupa, I.; Lazopoulos, A.; Panagiotopoulou, A.; Triantopoulou, S.; Paravatou-Petsotas, M.; Pietzsch, H.-J.; Pelecanou, M.; Papadopoulos, M.; Pirmettis, I.

Efficient Production of the PET radionuclide 133La for Theranostic Purposes in Targeted Alpha Therapy using the 134Ba(p,2n)133La Reaction

Brühlmann, S. A.; Kreller, M.; Pietzsch, H.-J.; Kopka, K.; Mamat, C.; Walther, M.; Reissig, F.

Involved research facilities

  • ZRT

Cyclam with a phosphinate-bis(phosphonate) pendant arm is a bone-targeting carrier of copper radionuclides

Pazderová, L.; Benešová, M.; Havlíčková, J.; Vojtíčková, M.; Kotek, J.; Lubal, P.; Ullrich, M.; Walther, M.; Schulze, S.; Neuber, C.; Rammelt, S.; Pietzsch, H.-J.; Pietzsch, J.; Kubíček, V.; Hermann, P.

Modulating the pharmacokinetic profile of Actinium-225-labeled macropa-derived radioconjugates by dual targeting of PSMA and albumin

Reissig, F.; Zarschler, K.; Novy, Z.; Petrik, M.; Bendova, K.; Kurfurstova, D.; Bouchal, J.; Ludik, M.-C.; Brandt, F.; Kopka, K.; Khoylou, M.; Pietzsch, H.-J.; Hajduch, M.; Mamat, C.

Introducing micro physiological systems to evaluate new radiopharmaceuticals: First attempts with radiolabeled cetuximab

Sihver, W.; Nitt-Weber, A.-K.; Behrens, S.; Ullrich, M.; Pietzsch, H.-J.; Namazian Jam, N.; Schmieder, F.; Sonntag, F.

Strained Ammonium Precursors for Radiofluorinations

Reissig, F.; Mamat, C.

“Clickable” albumin binders for modulating the tumor uptake of targeted radiopharmaceuticals

Brandt, F.; Ullrich, M.; Laube, M.; Kopka, K.; Bachmann, M.; Löser, R.; Pietzsch, J.; Pietzsch, H.-J.; van den Hoff, J.; Wodtke, R.

Involved research facilities

  • PET-Center

Related publications

Preparation of calix[4]arenes for chelation of selected divalent cations

Blumberg, M.; Al-Ameed, K.; Eiselt, E.; Luber, S.; Mamat, C.

2021

Molecular Response to Combined Molecular- and External Radiotherapy in Head and Neck Squamous Cell Carcinoma (HNSCC).

Rassamegevanon, T.; Feindt, L.; Koi, L.; Müller, J.; Freudenberg, R.; Löck, S.; Sihver, W.; Çevik, E.; Christel Kühn, A.; von Neubeck, C.; Linge, A.; Pietzsch, H.-J.; Kotzerke, J.; Baumann, M.; Krause, M.; Dietrich, A.

Strategic Evaluation of the Traceless Staudinger Ligation for Radiolabeling with the Tricarbonyl Core

Mamat, C.; Jentschel, C.; Köckerling, M.; Steinbach, J.

Aktuelle Entwicklungen aus den Radiopharmazeutischen Wissenschaften für theranostische Anwendungen - Editorial

Mamat, C.; Kopka, K.

Towards Targeted Alpha Therapy with Actinium 225: Chelators for Mild Condition Radiolabeling and Targeting PSMA – a Proof of Concept Study

Reissig, F.; Bauer, D.; Zarschler, K.; Novy, Z.; Bendova, K.; Kopka, K.; Pietzsch, H.-J.; Petrik, M.; Mamat, C.

Radiotherapy enhances uptake and efficacy of 90Y-cetuximab: A preclinical trial

Dietrich, A.; Andreeff, M.; Koi, L.; Bergmann, R.; Schubert, M.; Schreiner, L.; Löck, S.; Sihver, W.; Freudenberg, R.; Hering, S.; Pietzsch, H.-J.; Steinbach, J.; Kotzerke, J.; Baumann, M.; Krause, M.

Involved research facilities

  • PET-Center

The Impact of Barium Isotopes in Radiopharmacy and Nuclear Medicine – from Past to Presence

Reissig, F.; Kopka, K.; Mamat, C.

Die Bedeutung des Elementes Barium in der Nuklearmedizin

Reissig, F.; Kopka, K.; Mamat, C.

Radiolabelled Cyclic Bisarylmercury: High Chemical and in vivo Stability for Theranostics

Gilpin, I. M.; Ullrich, M.; Wünsche, T.; Zarschler, K.; Lebeda, O.; Pietzsch, J.; Pietzsch, H.-J.; Walther, M.

2020

Recent insights in barium-131 as a diagnostic match for radium-223: cyclotron production, separation, labeling and imaging

Reissig, F.; Bauer, D.; Ullrich, M.; Kreller, M.; Pietzsch, J.; Mamat, C.; Kopka, K.; Pietzsch, H.-J.; Walther, M.

A radiopharmacologist's and radiochemist's view on targeting the Eph/ephrin receptor tyrosine kinase system

Neuber, C.; Belter, B.; Mamat, C.; Pietzsch, J.

Light-Activated Carbon Monoxide Prodrugs Based on Bipyridyl Dicarbonyl Ruthenium(II) Complexes

Geri, S.; Krunclova, T.; Janouskova, O.; Panek, J.; Hruby, M.; Hernandez-Valdes, D.; Probst, B.; Alberto, R.; Mamat, C.; Kubeil, M.; Stephan, H.

Contemporary Synthesis of Ultrasmall (sub-10 nm) Upconverting Nanomaterials

Joshi, T.; Mamat, C.; Stephan, H.

Synthesis, radiolabeling and first biological characterization of 18F-labeled xanthine derivatives for PET imaging of Eph receptors

Pretze, M.; Neuber, C.; Kinski, E.; Belter, B.; Köckerling, M.; Caflisch, A.; Steinbach, J.; Pietzsch, J.; Mamat, C.

Involved research facilities

  • PET-Center

Sub-10 nm Radiolabeled Barium Sulfate Nanoparticles as Carriers for Theranostic Applications and Targeted Alpha Therapy

Reissig, F.; Zarschler, K.; Hübner, R.; Pietzsch, H.-J.; Kopka, K.; Mamat, C.

Formation of calix[4]arenes with acyloxycarboxylate functions

Bauer, D.; Stipurin, S.; Köckerling, M.; Mamat, C.

2019

Introduction of the New Center for Radiopharmaceutical Cancer Research at Helmholtz-Zentrum Dresden-Rossendorf

Kreller, M.; Pietzsch, H.-J.; Walther, M.; Tietze, H.; Kaever, P.; Knieß, T.; Füchtner, F.; Steinbach, J.; Preusche, S.

A comparative evaluation of calix[4]arene-1,3-crown-6 as a ligand for selected divalent cations of radiopharmaceutical interest

Bauer, D.; Blumberg, M.; Köckerling, M.; Mamat, C.

Editorial for special issue "Jörg Steinbach"

Mamat, C.

A 224Ra-labeled polyoxopalladate as putative radiopharmaceutical

Gott, M.; Yang, P.; Kortz, U.; Stephan, H.; Pietzsch, H.-J.; Mamat, C.

Regulation of A375 melanoma cell adhesion and migration by EphB4 and EphrinB2 –insights from co-culture experiments

Neuber, C.; Laube, M.; Mamat, C.; Belter, B.; Pietzsch, J.

  • Journal of Cellular Biotechnology 5(2019)1, 27-42
    DOI: 10.3233/JCB-189011
    ISSN: 2352-3689

Radiochemical and radiopharmacological characterization of a 64Cu-labeled α-MSH analog conjugated with different chelators

Gao, F.; Sihver, W.; Bergmann, R.; Walther, M.; Stephan, H.; Belter, B.; Neuber, C.; Haase-Kohn, C.; Bolzati, C.; Pietzsch, J.; Pietzsch, H.-J.

Involved research facilities

  • PET-Center

Facile preparation of radium-doped, functionalized nanoparticles as carriers for targeted alpha therapy

Reissig, F.; Hübner, R.; Steinbach, J.; Pietzsch, H.-J.; Mamat, C.

2018

Improved Conjugation, 64-Cu Radiolabeling, in Vivo Stability, and Imaging Using Nonprotected Bifunctional Macrocyclic Ligands: Bis(Phosphinate) Cyclam (BPC) Chelators

David, T.; Hlinová, V.; Kubíček, V.; Bergmann, R.; Striese, F.; Berndt, N.; Szöllösi, D.; Hegedus, N.; Mathe, D.; Bachmann, M.; Pietzsch, H.-J.; Hermann, P.

Involved research facilities

  • PET-Center

NMR-based investigations of acyl-functionalized piperazines concerning their conformational behavior in solution

Steinberg, J.; Köckerling, M.; Wodtke, R.; Löser, R.; Mamat, C.

Synthesis, characterization and initial biological evaluation of [⁹⁹ᵐTc]Tc-tricarbonyl labeled DPA-α-MSH peptide derivatives for potential melanoma imaging

Gao, F.; Sihver, W.; Bergmann, R.; Belter, B.; Bolzati, C.; Salvarese, N.; Steinbach, J.; Pietzsch, J.; Pietzsch, H.-J.

Involved research facilities

  • PET-Center

Exploring pitfalls of 64Cu‑labeled EGFR‑targeting peptide GE11 as a potential PET tracer

Striese, F.; Sihver, W.; Gao, F.; Bergmann, R.; Walther, M.; Pietzsch, J.; Steinbach, J.; Pietzsch, H.-J.

Involved research facilities

  • PET-Center

Biodistribution studies of ultrasmall silicon nanoparticles and carbon dots in experimental rats and tumor mice

Licciardello, N.; Hunoldt, S.; Bergmann, R.; Singh, G.; Mamat, C.; Faramus, A.; Ddungu, J. L. Z.; Silvestrini, S.; Maggini, M.; de Cola, L.; Stephan, H.

Involved research facilities

  • PET-Center

Overexpression of receptor tyrosine kinase EphB4 triggers tumor growth and hypoxia in A375 melanoma xenografts: insights from multitracer small animal imaging experiments

Neuber, C.; Belter, B.; Meister, S.; Hofheinz, F.; Bergmann, R.; Pietzsch, H.-J.; Pietzsch, J.

Modified Calix[4]crowns as Molecular Receptors for Barium

Steinberg, J.; Bauer, D.; Reissig, F.; Köckerling, M.; Pietzsch, H.-J.; Mamat, C.

Chelation of heavy group 2 (radio)metals by p-tert-butylcalix[4]arene-1,3-crown-6 and logK determination via NMR

Bauer, D.; Gott, M.; Steinbach, J.; Mamat, C.

Facile Silylation of Cyclitols using Silyl-bis(triflates)

Topp, A.; Köckerling, M.; Reinke, H.; Miethchen, R.; Mamat, C.

Recent Progress using the Staudinger Ligation for Radiolabeling Applications

Mamat, C.; Gott, M.; Steinbach, J.

Involved research facilities

  • PET-Center

Structural and kinetic considerations for the application of the traceless Staudinger ligation to future 18F radiolabeling using XRD and 19F-NMR

Köckerling, M.; Mamat, C.

Involved research facilities

  • PET-Center

2017

Preparation of 18F-labeled building blocks for peptide conjugation using the "minimalist" approach

Omrane, M. A.; Zlatopolskiy, B. D.; Urusova, E.; Mamat, C.; Feni, L.; Neundorf, I.; Neumaier, B.

  • Poster
    22nd International Symposium on Radiopharmaceutical Sciences (ISRS 2017), Dresden, 14.-19.05.2017, Dresden, Deutschland
  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 60(2017)S1, S261
    DOI: 10.1002/jlcr.3508
    Cited 3 times in Scopus

Evaluation of Ba/Ra Polyoxopalladates for Radiopharmaceutical Applications

Gott, M.; Yang, P.; Kortz, U.; Pietzsch, H.-J.; Steinbach, J.; Mamat, C.

  • Poster
    22nd International Symposium on Radiopharmaceutical Sciences (ISRS 2017), Dresden, 14.-19.05.2017, Dresden, Deutschland
  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 60(2017)S1, S559
    DOI: 10.1002/jlcr.3508
    Cited 3 times in Scopus

Novel Functionalized Calixarenes as Host Molecules for Complexation with Alkaline Earth Metals

Steinberg, J.; Gott, M.; Pietzsch, H.-J.; Steinbach, J.; Mamat, C.

  • Poster
    22nd International Symposium on Radiopharmaceutical Sciences (ISRS 2017), Dresden, 14.-19.05.2017, Dresden, Deutschland
  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 60(2017)S1, S488
    DOI: 10.1002/jlcr.3508
    Cited 3 times in Scopus

Detection of Auger Electron Induced Strand Breaks on Plasmid DNA Caused by Technetium-99m Labeled Pyrene Derivatives

Wunderlich, G.; Reissig, F.; Mamat, C.; Pietzsch, H.-J.; Kotzerke, J.; Steinbach, J.

  • Poster
    22nd International Symposium on Radiopharmaceutical Sciences (ISRS 2017), Dresden, 14.-19.05.2017, Dresden, Deutschland
  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 60(2017)S1, S365
    DOI: 10.1002/jlcr.3508
    Cited 3 times in Scopus

Preparation of a novel radiotracer targeting the EphB4 receptor via radiofluorination using spiro azetidinium salts as precursor

Wiemer, J.; Steinbach, J.; Pietzsch, J.; Mamat, C.

Involved research facilities

  • PET-Center

A novel nanobody-based target module for retargeting of T lymphocytes to EGFR-expressing cancer cells via the modular UniCAR platform

Albert, S.; Arndt, C.; Feldmann, A.; Bergmann, R.; Bachmann, D.; Koristka, S.; Ludwig, F.; Ziller-Walter, P.; Kegler, A.; Gärtner, S.; Schmitz, M.; Ehninger, A.; Cartellieri, M.; Ehninger, G.; Pietzsch, H.-J.; Pietzsch, J.; Steinbach, J.; Bachmann, M.

A novel tumor pretargeting system based on complementary L-configured oligonucleotides

Schubert, M.; Bergmann, R.; Förster, C.; Sihver, W.; Vonhoff, S.; Klussmann, S.; Bethge, L.; Walther, M.; Schlesinger, J.; Pietzsch, J.; Steinbach, J.; Pietzsch, H.-J.

Involved research facilities

  • PET-Center

X-ray Structures of Succinimidyl Halobenzoates

Mamat, C.; Weiss, D.-H.; Köckerling, M.

Involved research facilities

  • PET-Center

2016

New insights into the pretargeting approach to image and treat tumours

Patra, M.; Zarschler, K.; Pietzsch, H.-J.; Stephan, H.; Gasser, G.

Melanoma targeting with [99mTc(N)(PNP3)]-labeled α-melanocyte stimulating hormone peptide analogs: Effects of cyclization on the radiopharmaceutical properties

Carta, D.; Salvarese, N.; Morellato, N.; Gao, F.; Sihver, W.; Pietzsch, H.-J.; Biondi, B.; Ruzza, P.; Refosco, F.; Carpanese, D.; Rosato, A.; Bolzati, C.

Direct and Auger electron-induced, single- and double-strand breaks on plasmid DNA caused by 99mTc-labeled pyrene derivatives and the effect of bonding distance

Reissig, F.; Mamat, C.; Steinbach, J.; Pietzsch, H.-J.; Freudenberg, R.; Kotzerke, J.; Wunderlich, G.

Nuclear and optical dual-labelled imaging agents: Design and challenges

Singh, G.; Gott, M.; Pietzsch, H.-J.; Stephan, H.

  • Open Access Logo Nuklearmedizin 55(2016)2, 41-50

Synthesis, dynamic NMR characterization and XRD studies of novel N,N’-substituted piperazines for bioorthogonal labeling

Mamat, C.; Pretze, M.; Gott, M.; Köckerling, M.

Involved research facilities

  • PET-Center

The Radiochemical and radiopharmaceutical applications of radium

Gott, M.; Steinbach, J.; Mamat, C.

Radiopharmacological characterization of 64Cu-labeled α-MSH analogs for potential use in imaging of malignant melanoma

Gao, F.; Sihver, W.; Jurischka, C.; Bergmann, R.; Haase-Kohn, C.; Belter, B.; Steinbach, J.; Carta, D.; Bolzati, C.; Calderan, A.; Pietzsch, J.; Pietzsch, H.-J.

2015

Cyclam Derivatives with a Bis(phosphinate) or a Phosphinato−Phosphonate Pendant Arm: Ligands for Fast and Efficient Copper(II) Complexation for Nuclear Medical Applications

David, T.; Kubićek, V.; Gutten, O.; Lubal, P.; Kotek, J.; Pietzsch, H.-J.; Rulíśek, L.; Hermann, P.

18F-Labeled 1,4-Dioxa-8-azaspiro[4.5]decane Derivative: Synthesis and Biological Evaluation of a σ1 Receptor Radioligand with Low Lipophilicity as Potent Tumor Imaging Agent

Xie, F.; Bergmann, R.; Kniess, T.; Deuther-Conrad, W.; Mamat, C.; Neuber, C.; Liu, B.; Steinbach, J.; Brust, P.; Pietzsch, J.; Jia, H.

Involved research facilities

  • PET-Center

Methods to increase the metabolic stability of 18F-radiotracers

Kuchar, M.; Mamat, C.

Involved research facilities

  • PET-Center

In vivo Demonstration of an Active Tumor Pretargeting Approach with Peptide Nucleic Acid Bioconjugates as Complementary System

Leonidova, A.; Foerster, C.; Zarschler, K.; Schubert, M.; Pietzsch, H.-J.; Steinbach, J.; Bergmann, R.; Metzler-Nolte, N.; Stephan, H.; Gasser, G.

Involved research facilities

  • PET-Center

Novel indole-based sigma-2 receptor ligands: synthesis, structure–affinity relationship and antiproliferative activity

Xie, F.; Kniess, T.; Neuber, C.; Deuther-Conrad, W.; Mamat, C.; Liebermann, B. P.; Liu, B.; Mach, R. H.; Brust, P.; Steinbach, J.; Pietzsch, J.; Jia, H.

Involved research facilities

  • PET-Center

Synthesis and Molecular Structure of 2-(Diphenylphosphano) phenyl Benzoate Borane Adduct

Mamat, C.; Köckerling, M.

Development of indazolylpyrimidine derivatives as high-affine EphB4 receptor ligands and potential PET-radiotracers

Ebert, K.; Wiemer, J.; Caballero, J.; Köckerling, M.; Steinbach, J.; Pietzsch, J.; Mamat, C.

Involved research facilities

  • PET-Center

Theranostic mercury: 197(m)Hg with high specific activity for imaging and therapy

Walther, M.; Preusche, S.; Bartel, S.; Wunderlich, G.; Freudenberg, R.; Steinbach, J.; Pietzsch, H.-J.

Involved research facilities

  • PET-Center

Bifunctional Cyclam-Based Ligands with Phosphorus Acid Pendant Moieties for Radiocopper Separation – Thermodynamic and Kinetic Studies

Paúrová, M.; Havlíčková, J.; Pospíšilová, A.; Vetrík, M.; Císařová, I.; Stephan, H.; Pietzsch, H.-J.; Hrubý, M.; Hermann, P.; Kotek, J.

Polyoxometalates - potent and selective ecto-nucleotidase inhibitors

Lee, S.-Y.; Fiene, A.; Li, W.; Hank, T.; Brylev, K.; Fedovrov, V.; Lecka, J.; Haider, A.; Pietzsch, H.-J.; Zimmermann, H.; Sévigny, J.; Kortz, U.; Stephan, H.; Müller, C. E.

Evaluation of Novel Fluorescence Probes for Conjugation Purposes Using the Traceless Staudinger Ligation

Wodtke, R.; König, J.; Pigorsch, A.; Köckerling, M.; Mamat, C.

Involved research facilities

  • PET-Center

2014

Preparation of 4-Halobenzoate Containing Phosphane Based Building Blocks for Labeling Reactions Using the Traceless Staudinger Ligation

Mamat, C.; Köckerling, M.

Involved research facilities

  • PET-Center

X-ray structure of 2-(diphenylphosphano)phenyl-4-(hydroxymethyl)benzoate

Mamat, C.; Flemming, A.; Köckerling, M.

Involved research facilities

  • PET-Center

Assessment of the best N3− donors in preparation of [M(N)(PNP)]-based (M = 99mTc-; 188Re) target-specific radiopharmaceuticals: Comparison among succinic dihydrazide (SDH), N-methyl-S-methyl dithiocarbazate (HDTCZ) and PEGylated N-methyl-S-methyl dithiocarbazate (HO2C-PEG600-DTCZ)

Carta, D.; Jentschel, C.; Thieme, S.; Salvarese, N.; Morellato, N.; Refosco, F.; Ruzza, P.; Bergmann, R.; Pietzsch, H.-J.; Bolzati, C.

Involved research facilities

  • PET-Center

Radiofluorination and first radiopharmacological characterization of a SWLAY peptide-based ligand targeting EphA2

Pretze, M.; Mosch, B.; Bergmann, R.; Steinbach, J.; Pietzsch, J.; Mamat, C.

Involved research facilities

  • PET-Center

Visualizing inflammation activity in rheumatoid arthritis with Tc-99 m Anti-CD4-mAb fragment scintigraphy

Steinhoff, K.; Pierer, M.; Siegert, J.; Pigla, U.; Laub, R.; Hesse, S.; Seidel, W.; Sorger, D.; Seese, A.; Künstler, J.-U.; Pietzsch, H.-J.; Lincke, T.; Rullmann, M.; Emmrich, F.; Sabri, O.

Radiolabeled anti-EGFR-antibody improves local tumor control after external beam radiotherapy and offers theragnostic potential

Koi, L.; Bergmann, R.; Brüchner, K.; Pietzsch, J.; Pietzsch, H.-J.; Krause, M.; Steinbach, J.; Zips, D.; Baumann, M.

Involved research facilities

  • PET-Center

2013

Regioselective Synthesis of Trichloromethyl-Substituted Salicylates and Cyclohexenones by One-Pot Cyclizations of 1,3-Bis(trimethylsilyloxy)buta-1,3-dienes

Reimann, S.; Bunescu, A.; Petrosyana, A.; Sharif, M.; Erfle, S.; Mamat, C.; Ghochikyan, T. V.; Saghyan, A. S.; Spannenberg, A.; Villinger, A.; Langer, P.

Quantitative Structure Property Relationship of logP for Radiopharmaceutical Technetium and Rhenium Complexes by using Molecular Dynamics Calculations

Yoshizuka, K.; Pietzsch, H.-J.; Seifert, S.; Stephan, H.

  • Open Access Logo Solvent Extraction Research and Development 20(2013), 15-27

Recent Trends in Bioorthogonal Click-Radiolabeling Reactions Using Fluorine-18

Pretze, M.; Pietzsch, D.; Mamat, C.

Involved research facilities

  • PET-Center

Condensation of the dianion of ethyl acetoacetate with perfluoroalkyl iodides. Application to the synthesis of 3-perfluoroalkylsalicylic acids

Mamat, C.; Langer, P.

Automated preparation of [18F]AFP and [18F]BFP: Two novel bifunctional 18F-labeling building blocks for Huisgen-click

Pretze, M.; Mamat, C.

Involved research facilities

  • PET-Center

An Efficient Bioorthogonal Strategy Using CuAAC Click Chemistry for Radiofluorinations of SNEW Peptides and the Role of Copper Depletion

Pretze, M.; Kuchar, M.; Bergmann, R.; Steinbach, J.; Pietzsch, J.; Mamat, C.

Involved research facilities

  • PET-Center

Design and Development of 99mTc-‘4 + 1’-Labeled Dextran-Mannose Derivatives as Potential Radiopharmaceuticals for Sentinel Lymph Node Detection

Giglio, J.; Fernandez, S.; Jentschel, C.; Pietzsch, H.-J.; Papadopoulos, M.; Pelecanou, M.; Pirmettis, I.; Paolino, A.; Rey, A.

Ga-68- and Cu-64-Labeled NOTA-Albumin Conjugates for PET Sentinel Lymph Node Imaging

Schiller, E.; Bergmann, R.; Wunderlich, G.; Andreeff, M.; Jacob, A.; Pietzsch, H.-J.

Involved research facilities

  • PET-Center

Synthesis of Short and Versatile Heterobifunctional Linkers for Conjugation Purposes of Bioactive Molecules with (Radio-)Labels

Heldt, J.-M.; Kerzendörfer, O.; Mamat, C.; Starke, F.; Pietzsch, H.-J.; Steinbach, J.

Inactivation of HNSCC Cells by 90Y-Labeled Cetuximab Strictly Depends on the Number of Induced DNA Double-Strand Breaks

Saker, J.; Kriegs, M.; Zenker, M.; Heldt, J.-M.; Eke, I.; Pietzsch, H.-J.; Grénman, R.; Cordes, N.; Petersen, C.; Baumann, M.; Steinbach, J.; Dikomey, E.; Kasten-Pisula, U.

[68Ga]NS3-RGD and [68Ga] Oxo-DO3A-RGD for imaging αvβ3 integrin expression: synthesis, evaluation, and comparison

Knetsch, P. A.; Petrik, M.; Rangger, C.; Seidel, G.; Pietzsch, H.-J.; Virgolini, I.; Decristoforo, C.; Haubner, R.

High specific activity 61Cu via 64Zn(p,α)61Cu reaction at low proton energies

Thieme, S.; Walther, M.; Preusche, S.; Rajander, J.; Pietzsch, H.-J.; Solin, O.; Steinbach, J.

Involved research facilities

  • PET-Center

2012

Cellular and molecular properties of 90Y-labeled cetuximab in combination with radiotherapy on human tumor cells in vitro

Saki, M.; Toulany, M.; Sihver, W.; Zenker, M.; Heldt, J.-M.; Mosch, B.; Pietzsch, H.-J.; Baumann, M.; Steinbach, J.; Rodemann, H. P.

Involved research facilities

  • PET-Center

Fluorine-18-Radiolabeling and Radiopharmacological Characterization of a Benzodioxolylpyrimidine as a Radiotracer Targeting the Receptor Tyrosine Kinase EphB4

Mamat, C.; Mosch, B.; Neuber, C.; Köckerling, M.; Bergmann, R.; Pietzsch, J.

Involved research facilities

  • PET-Center

Synthesis and characterization of novel tetrahedral copper(I) complexes comprising tridentate PNP-aminodiphosphines and tetradentate PN(X)P-substituted aminodiphosphines (X = O, S)

Peruzzo, V.; Pretzsch, C.; Tisato, F.; Porchia, M.; Refosco, F.; Marzano, C.; Gandin, V.; Schiller, E.; Walther, M.; Pietzsch, H.-J.

Synthesis, in vitro and in vivo characterization of novel 99mTc-‘4+1’-labeled 5-nitroimidazole derivatives as potential agents for imaging hypoxia

Giglio, J.; Fernández, S.; Pietzsch, H.-J. D.; Dematteis, S.; Moreno, M.; Pacheco, J. P.; Cerecetto, H.; Rey, A.

Module-assisted preparation of 64Cu with high specific activity

Thieme, S.; Walther, M.; Pietzsch, H.-J.; Henniger, J.; Preusche, S.; Mäding, P.; Steinbach, J.

Involved research facilities

  • PET-Center

Synthesis and Molecular Structure of tert-Butyl 4-(2-tert-butoxy-2-oxoethyl)piperazine-1-carboxylate

Mamat, C.; Flemming, A.; Köckerling, M.

Involved research facilities

  • PET-Center

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