Publications of Institute of Radiopharmaceutical Cancer Research
284 Publications2016
Polyglycerol-Based Copper Chelators for the Transport and Release of Copper Ions in Biological Environments
Albrecht, R.; Fehse, S.; Pant, K.; Nowag, S.; Stephan, H.; Haag, R.; Tzschucke, C. C.
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Macromolecular Bioscience 16(2016), 412-419
DOI: 10.1002/mabi.201500284
Cited 13 times in Scopus
Direct and Auger electron-induced, single- and double-strand breaks on plasmid DNA caused by 99mTc-labeled pyrene derivatives and the effect of bonding distance
Reissig, F.; Mamat, C.; Steinbach, J.; Pietzsch, H.-J.; Freudenberg, R.; Kotzerke, J.; Wunderlich, G.
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PLOS ONE 10(2016)9, e0161973
Online First (2016) DOI: 10.1371/journal.pone.0161973
Cited 27 times in Scopus
Ultrasmall inorganic nanoparticles: state-of-the-art and perspectives for biomedical applications
Zarschler, K.; Rocks, L.; Licciardello, N.; Boselli, L.; Polo, E.; Pombo Garcia, K.; de Cola, L.; Stephan, H.; Dawson, K. A.
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Nanomedicine: Nanotechnology, Biology, and Medicine 12(2016)6, 1663-1701
Online First (2016) DOI: 10.1016/j.nano.2016.02.019
Cited 233 times in Scopus
Synthesis, dynamic NMR characterization and XRD studies of novel N,N’-substituted piperazines for bioorthogonal labeling
Mamat, C.; Pretze, M.; Gott, M.; Köckerling, M.
Involved research facilities
- PET-Center
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Beilstein Journal of Organic Chemistry 12(2016), 2479-2489
DOI: 10.3762/bjoc.12.242
Cited 13 times in Scopus
The Radiochemical and radiopharmaceutical applications of radium
Gott, M.; Steinbach, J.; Mamat, C.
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Open Chemistry 14(2016), 118-129
DOI: 10.1515/chem-2016-0011
Cited 37 times in Scopus
Radiopharmacological characterization of 64Cu-labeled α-MSH analogs for potential use in imaging of malignant melanoma
Gao, F.; Sihver, W.; Jurischka, C.; Bergmann, R.; Haase-Kohn, C.; Belter, B.; Steinbach, J.; Carta, D.; Bolzati, C.; Calderan, A.; Pietzsch, J.; Pietzsch, H.-J.
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Amino Acids 48(2016)3, 833-847
Online First (2015) DOI: 10.1007/s00726-015-2131-x
Cited 16 times in Scopus
2015
Cyclam Derivatives with a Bis(phosphinate) or a Phosphinato−Phosphonate Pendant Arm: Ligands for Fast and Efficient Copper(II) Complexation for Nuclear Medical Applications
David, T.; Kubićek, V.; Gutten, O.; Lubal, P.; Kotek, J.; Pietzsch, H.-J.; Rulíśek, L.; Hermann, P.
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Inorganic Chemistry 54(2015), 11751-11766
Online First (2015) DOI: 10.1021/acs.inorgchem.5b01791
Cited 30 times in Scopus
18F-Labeled 1,4-Dioxa-8-azaspiro[4.5]decane Derivative: Synthesis and Biological Evaluation of a σ1 Receptor Radioligand with Low Lipophilicity as Potent Tumor Imaging Agent
Xie, F.; Bergmann, R.; Kniess, T.; Deuther-Conrad, W.; Mamat, C.; Neuber, C.; Liu, B.; Steinbach, J.; Brust, P.; Pietzsch, J.; Jia, H.
Involved research facilities
- PET-Center
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Journal of Medicinal Chemistry 58(2015), 5395-5407
DOI: 10.1021/acs.jmedchem.5b00593
ISSN: 0022-2623
Cited 23 times in Scopus
Methods to increase the metabolic stability of 18F-radiotracers
Kuchar, M.; Mamat, C.
Involved research facilities
- PET-Center
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Molecules 20(2015), 16186-16220
DOI: 10.3390/molecules200916186
Cited 67 times in Scopus
In vivo Demonstration of an Active Tumor Pretargeting Approach with Peptide Nucleic Acid Bioconjugates as Complementary System
Leonidova, A.; Foerster, C.; Zarschler, K.; Schubert, M.; Pietzsch, H.-J.; Steinbach, J.; Bergmann, R.; Metzler-Nolte, N.; Stephan, H.; Gasser, G.
Involved research facilities
- PET-Center
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Chemical Science 6(2015), 5601-5616
Online First (2015) DOI: 10.1039/c5sc00951k
Cited 33 times in Scopus
Copper(II) cyclam complexes with N-propionic acid pendant arms
Kubeil, M.; Zarschler, K.; Pietzsch, J.; Kraus, W.; Comba, P.; Stephan, H.
Involved research facilities
- PET-Center
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European Journal of Inorganic Chemistry 2015(2015), 4013-4023
Online First (2015) DOI: 10.1002/ejic.201500510
Cited 4 times in Scopus
Novel indole-based sigma-2 receptor ligands: synthesis, structure–affinity relationship and antiproliferative activity
Xie, F.; Kniess, T.; Neuber, C.; Deuther-Conrad, W.; Mamat, C.; Liebermann, B. P.; Liu, B.; Mach, R. H.; Brust, P.; Steinbach, J.; Pietzsch, J.; Jia, H.
Involved research facilities
- PET-Center
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MedChemComm 6(2015), 1093-1103
DOI: 10.1039/c5md00079c
Cited 15 times in Scopus
Synthesis and Molecular Structure of 2-(Diphenylphosphano) phenyl Benzoate Borane Adduct
Mamat, C.; Köckerling, M.
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Crystals 5(2015), 9-13
DOI: 10.3390/cryst5010009
ISSN: 2073-4352
Cited 1 times in Scopus
CuII-selective bispidine–dye conjugates
Bronx, D.; Comba, P.; Herten, D.-P.; Kimmle, E.; Morgen, M.; Rühl, C. L.; Rybina, A.; Stephan, H.; Storch, G.; Wadepohl, H.
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Journal of Inorganic Biochemistry 148(2015), 78-83
Online First (2015) DOI: 10.1016/j.jinorgbio.2015.05.009
Cited 10 times in Scopus
Synthesis and Biodistribution Studies of 3H- and 64Cu-labeled Dendritic Polyglycerol and Dendritic Polyglycerol Sulfate
Pant, K.; Gröger, D.; Bergmann, R.; Pietzsch, J.; Steinbach, J.; Graham, B.; Spiccia, L.; Berthon, F.; Czarny, B.; Devel, L.; Dive, V.; Stephan, H.; Haag, R.
Involved research facilities
- PET-Center
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Bioconjugate Chemistry 26(2015), 906-918
Online First (2015) DOI: 10.1021/acs.bioconjchem.5b00127
Cited 32 times in Scopus
Development of indazolylpyrimidine derivatives as high-affine EphB4 receptor ligands and potential PET-radiotracers
Ebert, K.; Wiemer, J.; Caballero, J.; Köckerling, M.; Steinbach, J.; Pietzsch, J.; Mamat, C.
Involved research facilities
- PET-Center
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Bioorganic & Medicinal Chemistry 23(2015), 6025-6035
DOI: 10.1016/j.bmc.2015.06.040
Cited 11 times in Scopus
Theranostic mercury: 197(m)Hg with high specific activity for imaging and therapy
Walther, M.; Preusche, S.; Bartel, S.; Wunderlich, G.; Freudenberg, R.; Steinbach, J.; Pietzsch, H.-J.
Involved research facilities
- PET-Center
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Applied Radiation and Isotopes 97(2015), 177-181
DOI: 10.1016/j.apradiso.2015.01.001
Cited 25 times in Scopus
Bifunctional Cyclam-Based Ligands with Phosphorus Acid Pendant Moieties for Radiocopper Separation – Thermodynamic and Kinetic Studies
Paúrová, M.; Havlíčková, J.; Pospíšilová, A.; Vetrík, M.; Císařová, I.; Stephan, H.; Pietzsch, H.-J.; Hrubý, M.; Hermann, P.; Kotek, J.
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Chemistry - A European Journal 21(2015), 4671-4687
Online First (2015) DOI: 10.1002/chem.201405777
Cited 18 times in Scopus
Polyoxometalates - potent and selective ecto-nucleotidase inhibitors
Lee, S.-Y.; Fiene, A.; Li, W.; Hank, T.; Brylev, K.; Fedovrov, V.; Lecka, J.; Haider, A.; Pietzsch, H.-J.; Zimmermann, H.; Sévigny, J.; Kortz, U.; Stephan, H.; Müller, C. E.
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Biochemical Pharmacology 93(2015), 171-181
DOI: 10.1016/j.bcp.2014.11.002
Cited 98 times in Scopus
Evaluation of Novel Fluorescence Probes for Conjugation Purposes Using the Traceless Staudinger Ligation
Wodtke, R.; König, J.; Pigorsch, A.; Köckerling, M.; Mamat, C.
Involved research facilities
- PET-Center
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Dyes and Pigments 113(2015), 263-273
Online First (2014) DOI: 10.1016/j.dyepig.2014.08.022
Cited 16 times in Scopus
2014
Preparation of 4-Halobenzoate Containing Phosphane Based Building Blocks for Labeling Reactions Using the Traceless Staudinger Ligation
Mamat, C.; Köckerling, M.
Involved research facilities
- PET-Center
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Synthesis 46(2014)2, 387-394
DOI: 10.1055/s-0034-1379487
Cited 11 times in Scopus
X-ray structure of 2-(diphenylphosphano)phenyl-4-(hydroxymethyl)benzoate
Mamat, C.; Flemming, A.; Köckerling, M.
Involved research facilities
- PET-Center
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Acta Crystallographica Section E E70(2014), o1288-o1289
DOI: 10.1107/S1600536814024623
ISSN: 1600-5368
Characterization of circulating microparticle-associated CD39 family ecto-nucleotidases in human plasma
Jiang, Z. G.; Wu, Y.; Csizmadia, E.; Feldbrügge, L.; Enjyoji, K.; Tigges, J.; Toxavidis, V.; Stephan, H.; Müller, C. E.; Mcknight, C. J.; Moss, A.; Robson, S. C.
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Purinergic Signalling 10(2014), 611-618
Online First (2014) DOI: 10.1007/s11302-014-9423-6
Cited 26 times in Scopus
The Ti7-Containing, Tetrahedral 36-Tungsto-4-Arsenate(III)[Ti6(TiO6)(AsW9O33)4]20-
Wang, K.-Y.; Bassil, B. S.; Lin, Z. G.; Haider, A.; Cao, J.; Stephan, H.; Viehweger, K.; Kortz, U.
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Dalton Transactions 43(2014), 16143-16146
DOI: 10.1039/c4dt02494j
Cited 20 times in Scopus
Bispidines for dual imaging
Stephan, H.; Walther, M.; Fähnemann, S.; Ceroni, P.; Molloy, J.; Bergamini, G.; Heisig, F.; Müller, C. E.; Kraus, W.; Comba, P.
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Chemistry - A European Journal 20(2014), 17011-17018
Online First (2014) DOI: 10.1002/chem.201404086
Cited 33 times in Scopus
Zwitterionic-Coated "Stealth" Nanoparticles for Biomedical Applications: Recent Advances in Countering Biomolecular Corona Formation and Uptake by the Mononuclear Phagocyte System
Pombo Garcia, K.; Zarschler, K.; Barbaro, L.; Barreto, J. A.; O'Malley, W.; Spiccia, L.; Stephan, H.; Graham, B.
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Small 10(2014), 2516-2529
DOI: 10.1002/smll.201303540
ISSN: 1613-6810
Cited 404 times in Scopus
Assessment of the best N3− donors in preparation of [M(N)(PNP)]-based (M = 99mTc-; 188Re) target-specific radiopharmaceuticals: Comparison among succinic dihydrazide (SDH), N-methyl-S-methyl dithiocarbazate (HDTCZ) and PEGylated N-methyl-S-methyl dithiocarbazate (HO2C-PEG600-DTCZ)
Carta, D.; Jentschel, C.; Thieme, S.; Salvarese, N.; Morellato, N.; Refosco, F.; Ruzza, P.; Bergmann, R.; Pietzsch, H.-J.; Bolzati, C.
Involved research facilities
- PET-Center
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Nuclear Medicine and Biology 41(2014), 570-581
DOI: 10.1016/j.nucmedbio.2014.04.126
Cited 9 times in Scopus
Bispidine dioxotetraaza macrocycles: a new class of bispidines for 64Cu PET imaging
Comba, P.; Kubeil, M.; Pietzsch, J.; Rudolf, H.; Stephan, H.; Zarschler, K.
Involved research facilities
- PET-Center
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Inorganic Chemistry 53(2014), 6698-6707
Online First (2014) DOI: 10.1021/ic500476u
Cited 29 times in Scopus
Radiofluorination and first radiopharmacological characterization of a SWLAY peptide-based ligand targeting EphA2
Pretze, M.; Mosch, B.; Bergmann, R.; Steinbach, J.; Pietzsch, J.; Mamat, C.
Involved research facilities
- PET-Center
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Journal of Labelled Compounds and Radiopharmaceuticals 57(2014), 660-665
DOI: 10.1002/jlcr.3237
Cited 12 times in Scopus
EGF receptor-targeting peptide conjugate incorporating a near-IR fluorescent dye and a novel 1,4,7-triazacyclononane-based 64Cu(II) chelator assembled via click chemistry
Viehweger, K.; Barbaro, L.; Pombo García, K.; Joshi, T.; Geipel, G.; Steinbach, J.; Stephan, H.; Spiccia, L.; Graham, B.
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Bioconjugate Chemistry 25(2014)5, 1011-1022
Online First (2014) DOI: 10.1021/bc5001388
Cited 25 times in Scopus
Diagnostic nanoparticle targeting of the EGF-receptor in complex biological conditions using single-domain antibodies
Zarschler, K.; Prapainop, K.; Mahon, E.; Rocks, L.; Bramini, M.; Kelly, P.; Stephan, H.; Dawson, K. A.
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Nanoscale 6(2014), 6046-6056
Online First (2014) DOI: 10.1039/c4nr00595c
Cited 69 times in Scopus
Visualizing inflammation activity in rheumatoid arthritis with Tc-99 m Anti-CD4-mAb fragment scintigraphy
Steinhoff, K.; Pierer, M.; Siegert, J.; Pigla, U.; Laub, R.; Hesse, S.; Seidel, W.; Sorger, D.; Seese, A.; Künstler, J.-U.; Pietzsch, H.-J.; Lincke, T.; Rullmann, M.; Emmrich, F.; Sabri, O.
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Nuclear Medicine and Biology 41(2014), 350-354
DOI: 10.1016/j.nucmedbio.2013.12.018
Cited 11 times in Scopus
Radiolabeled anti-EGFR-antibody improves local tumor control after external beam radiotherapy and offers theragnostic potential
Koi, L.; Bergmann, R.; Brüchner, K.; Pietzsch, J.; Pietzsch, H.-J.; Krause, M.; Steinbach, J.; Zips, D.; Baumann, M.
Involved research facilities
- PET-Center
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Radiotherapy and Oncology 110(2014), 362-369
DOI: 10.1016/j.radonc.2013.12.001
Cited 47 times in Scopus
Establishment of two complementary in vitro assays for radiocopper complexes achieving reliable and comparable evaluation of in vivo stability
Zarschler, K.; Kubeil, M.; Stephan, H.
Involved research facilities
- PET-Center
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RSC Advances 4(2014), 10157-10164
DOI: 10.1039/c3ra47302c
Cited 34 times in Scopus
2013
Regioselective Synthesis of Trichloromethyl-Substituted Salicylates and Cyclohexenones by One-Pot Cyclizations of 1,3-Bis(trimethylsilyloxy)buta-1,3-dienes
Reimann, S.; Bunescu, A.; Petrosyana, A.; Sharif, M.; Erfle, S.; Mamat, C.; Ghochikyan, T. V.; Saghyan, A. S.; Spannenberg, A.; Villinger, A.; Langer, P.
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Helvetica Chimica Acta 96(2013), 1955-1967
DOI: 10.1002/hlca.201200595
High-yield production of functional soluble single-domain antibodies in the cytoplasm of Escherichia coli
Zarschler, K.; Witecy, S.; Kapplusch, F.; Foerster, C.; Stephan, H.
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Microbial Cell Factories 12(2013), 97
Online First (2013) DOI: 10.1186/1475-2859-12-97
Cited 67 times in Scopus
Synthesis and radiopharmacological evaluation of 64Cu-labeled bombesin analogs featuring a bis(2-pyridylmethyl) 1,4,7-triazacyclononane chelator
Bergmann, R.; Ruffani, A.; Graham, B.; Spiccia, L.; Steinbach, J.; Pietzsch, J.; Stephan, H.
Involved research facilities
- PET-Center
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European Journal of Medicinal Chemistry 70(2013), 434-446
Online First (2013) DOI: 10.1016/j.ejmech.2013.10.013
Cited 27 times in Scopus
Design, synthesis, characterisation and in vitro studies of hydrophilic, colloidally stable, 64Cu(II)-labelled, ultra-small iron oxide nanoparticles in a range of human cell lines
Pombo Garcia, K.; Zarschler, K.; Barreto, J. A.; Hesse, J.; Spiccia, L.; Graham, B.; Stephan, H.
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RSC Advances 3(2013), 22443-22454
Online First (2013) DOI: 10.1039/C3RA43726D
Cited 18 times in Scopus
Quantitative Structure Property Relationship of logP for Radiopharmaceutical Technetium and Rhenium Complexes by using Molecular Dynamics Calculations
Yoshizuka, K.; Pietzsch, H.-J.; Seifert, S.; Stephan, H.
- Solvent Extraction Research and Development 20(2013), 15-27
Recent Trends in Bioorthogonal Click-Radiolabeling Reactions Using Fluorine-18
Pretze, M.; Pietzsch, D.; Mamat, C.
Involved research facilities
- PET-Center
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Molecules 18(2013), 8618-8665
DOI: 10.3390/molecules18078618
ISSN: 1420-3049
Cited 73 times in Scopus
Optimization of Pentadentate Bispidines as Bifunctional Chelators for 64Cu Positron Emission Tomography (PET)
Comba, P.; Hunoldt, S.; Morgen, M.; Pietzsch, J.; Stephan, H.; Wadepohl, H.
Involved research facilities
- PET-Center
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Inorganic Chemistry 52(2013), 8131-8143
Online First (2013) DOI: 10.1021/ic4008685
Cited 43 times in Scopus
The computation of lipophilicities of 64Cu PET systems based on a novel approach for fluctuating charges
Comba, P.; Martin, B.; Sanyal, A.; Stephan, H.
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Dalton Transactions 42(2013)31, 11066-11110
Online First (2013) DOI: 10.1039/c3dt51049b
Cited 14 times in Scopus
Condensation of the dianion of ethyl acetoacetate with perfluoroalkyl iodides. Application to the synthesis of 3-perfluoroalkylsalicylic acids
Mamat, C.; Langer, P.
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Monatshefte für Chemie 144(2013), 1057-1061
DOI: 10.1007/s00706-013-0985-8
Automated preparation of [18F]AFP and [18F]BFP: Two novel bifunctional 18F-labeling building blocks for Huisgen-click
Pretze, M.; Mamat, C.
Involved research facilities
- PET-Center
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Journal of Fluorine Chemistry 150(2013), 25-35
DOI: 10.1016/j.jfluchem.2013.02.028
Cited 26 times in Scopus
An Efficient Bioorthogonal Strategy Using CuAAC Click Chemistry for Radiofluorinations of SNEW Peptides and the Role of Copper Depletion
Pretze, M.; Kuchar, M.; Bergmann, R.; Steinbach, J.; Pietzsch, J.; Mamat, C.
Involved research facilities
- PET-Center
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ChemMedChem 8(2013), 935-945
DOI: 10.1002/cmdc.201300053
Cited 24 times in Scopus
Design and Development of 99mTc-‘4 + 1’-Labeled Dextran-Mannose Derivatives as Potential Radiopharmaceuticals for Sentinel Lymph Node Detection
Giglio, J.; Fernandez, S.; Jentschel, C.; Pietzsch, H.-J.; Papadopoulos, M.; Pelecanou, M.; Pirmettis, I.; Paolino, A.; Rey, A.
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Cancer Biotherapy and Radiopharmaceuticals 28(2013), 541-551
Online First (2013) DOI: 10.1089/cbr.2012.1440
Cited 5 times in Scopus
Dendrimers as Nb3+ ligands: effect of generation on the efficiency of the sensitized lanthanide emission
Pillai, Z. S.; Ceroni, P.; Kubeil, M.; Heldt, J.-M.; Stephan, H.; Bergamini, G.
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Chemistry - An Asian Journal 8(2013), 771-777
DOI: 10.1002/asia.201201065
Cited 17 times in Scopus
Ga-68- and Cu-64-Labeled NOTA-Albumin Conjugates for PET Sentinel Lymph Node Imaging
Schiller, E.; Bergmann, R.; Wunderlich, G.; Andreeff, M.; Jacob, A.; Pietzsch, H.-J.
Involved research facilities
- PET-Center
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ISRN Molecular Imaging (2013), 386976
DOI: 10.1155/2013/386976
Synthesis of Short and Versatile Heterobifunctional Linkers for Conjugation Purposes of Bioactive Molecules with (Radio-)Labels
Heldt, J.-M.; Kerzendörfer, O.; Mamat, C.; Starke, F.; Pietzsch, H.-J.; Steinbach, J.
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Synlett 4(2013), 432-436
DOI: 10.1055/s-0032-1318198
Cited 7 times in Scopus
Inactivation of HNSCC Cells by 90Y-Labeled Cetuximab Strictly Depends on the Number of Induced DNA Double-Strand Breaks
Saker, J.; Kriegs, M.; Zenker, M.; Heldt, J.-M.; Eke, I.; Pietzsch, H.-J.; Grénman, R.; Cordes, N.; Petersen, C.; Baumann, M.; Steinbach, J.; Dikomey, E.; Kasten-Pisula, U.
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Journal of Nuclear Medicine 54(2013), 416-423
Online First (2013) DOI: 10.2967/jnumed.111.101857
Cited 15 times in Scopus
Copper(II) chemistry of the functionalized macrocycle cyclam tetrapropionic acid
Comba, P.; Emmerling, F.; Jakob, M.; Kraus, W.; Kubeil, M.; Morgen, M.; Pietzsch, J.; Stephan, H.
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Dalton Transactions 42(2013), 6142-6148
Online First (2012) DOI: 10.1039/C2DT32356G
Cited 7 times in Scopus
Polyoxometalates as versatile enzyme inhibitors
Stephan, H.; Kubeil, M.; Emmerling, F.; Müller, C. E.
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European Journal of Inorganic Chemistry 10-11(2013), 1585-1594
Online First (2012) DOI: 10.1002/ejic.201201224
Cited 131 times in Scopus
[68Ga]NS3-RGD and [68Ga] Oxo-DO3A-RGD for imaging αvβ3 integrin expression: synthesis, evaluation, and comparison
Knetsch, P. A.; Petrik, M.; Rangger, C.; Seidel, G.; Pietzsch, H.-J.; Virgolini, I.; Decristoforo, C.; Haubner, R.
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Nuclear Medicine and Biology 40(2013), 65-72
Online First (2012) DOI: 10.1016/j.nucmedbio.2012.09.006
Cited 17 times in Scopus
High specific activity 61Cu via 64Zn(p,α)61Cu reaction at low proton energies
Thieme, S.; Walther, M.; Preusche, S.; Rajander, J.; Pietzsch, H.-J.; Solin, O.; Steinbach, J.
Involved research facilities
- PET-Center
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Applied Radiation and Isotopes 72(2013), 169-176
DOI: 10.1016/j.apradiso.2012.11.007
Cited 22 times in Scopus
2012
Cellular and molecular properties of 90Y-labeled cetuximab in combination with radiotherapy on human tumor cells in vitro
Saki, M.; Toulany, M.; Sihver, W.; Zenker, M.; Heldt, J.-M.; Mosch, B.; Pietzsch, H.-J.; Baumann, M.; Steinbach, J.; Rodemann, H. P.
Involved research facilities
- PET-Center
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Strahlentherapie und Onkologie 9(2012), 823-832
DOI: 10.1007/s00066-012-0121-4
Cited 18 times in Scopus
Fluorine-18-Radiolabeling and Radiopharmacological Characterization of a Benzodioxolylpyrimidine as a Radiotracer Targeting the Receptor Tyrosine Kinase EphB4
Mamat, C.; Mosch, B.; Neuber, C.; Köckerling, M.; Bergmann, R.; Pietzsch, J.
Involved research facilities
- PET-Center
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ChemMedChem 7(2012)11, 1991-2003
Online First (2012) DOI: 10.1002/cmdc.201200264
Cited 26 times in Scopus
Synthesis and characterization of novel tetrahedral copper(I) complexes comprising tridentate PNP-aminodiphosphines and tetradentate PN(X)P-substituted aminodiphosphines (X = O, S)
Peruzzo, V.; Pretzsch, C.; Tisato, F.; Porchia, M.; Refosco, F.; Marzano, C.; Gandin, V.; Schiller, E.; Walther, M.; Pietzsch, H.-J.
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Inorganica Chimica Acta 387(2012), 163-172
DOI: 10.1016/j.ica.2012.01.012
Cited 5 times in Scopus
Synthesis, in vitro and in vivo characterization of novel 99mTc-‘4+1’-labeled 5-nitroimidazole derivatives as potential agents for imaging hypoxia
Giglio, J.; Fernández, S.; Pietzsch, H.-J. D.; Dematteis, S.; Moreno, M.; Pacheco, J. P.; Cerecetto, H.; Rey, A.
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Nuclear Medicine and Biology 39(2012), 679-686
Online First (2012) DOI: 10.1016/j.nucmedbio.2011.12.012
Cited 31 times in Scopus
Ecto-ATPase inhibition: ATP and adenosine release under physiological and ischemic in vivo conditions in the rat striatum
Melani, A.; Corti, F.; Stephan, H.; Müller, C. E.; Donati, C.; Bruni, P.; Vannucchi, M. G.; Pedata, F.
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Experimental Neurology 233(2012), 193-204
DOI: 10.1016/j.expneurol.2011.09.036
Cited 83 times in Scopus
Module-assisted preparation of 64Cu with high specific activity
Thieme, S.; Walther, M.; Pietzsch, H.-J.; Henniger, J.; Preusche, S.; Mäding, P.; Steinbach, J.
Involved research facilities
- PET-Center
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Applied Radiation and Isotopes 70(2012), 602-608
Online First (2012) DOI: 10.1016/j.apradiso.2012.01.019
Cited 71 times in Scopus
Synthesis and Molecular Structure of tert-Butyl 4-(2-tert-butoxy-2-oxoethyl)piperazine-1-carboxylate
Mamat, C.; Flemming, A.; Köckerling, M.
Involved research facilities
- PET-Center
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Crystals 2(2012), 90-95
DOI: 10.3390/cryst2010090
ISSN: 2073-4352
Cited 2 times in Scopus
The Synthesis and Molecular Structure of 2-(4-Methoxybenzyl)-4-nitro-2H-indazole
Ebert, K.; Köckerling, M.; Mamat, C.
Involved research facilities
- PET-Center
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Crystals 2(2012), 176-181
DOI: 10.3390/cryst2020176
Cited 1 times in Scopus
The Molecular Structure of 1,2:5,6-Di-O-isopropylidene-3-O-toluenesulfonyl-a-D-glucofuranose
Mamat, C.; Peppel, T.; Köckerling, M.
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Crystals 2(2012), 105-109
DOI: 10.3390/cryst2010105
ISSN: 2073-4352
Cited 6 times in Scopus
2011
Synthesis, colloidal stability and 64Cu labeling of iron oxide nanoparticles bearing different macrocyclic ligands
Barreto, J. A.; Matterna, M.; Graham, B.; Stephan, H.; Spiccia, L.
- New Journal of Chemistry 35(2011), 2705-2712
Impact of functionalized coligands on the pharmacokinetics of 99mTc(III) ‘4+1’ mixed-ligand complexes conjugated to bombesin
Künstler, J.-U.; Bergmann, R.; Gniazdowska, E.; Kozminski, P.; Walther, M.; Pietzsch, H.-J.
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Journal of Inorganic Biochemistry 105(2011), 1383-1390
DOI: 10.1016/j.jinorgbio.2011.07.002
Cited 13 times in Scopus
Maleimido-Functionalized NOTA Derivatives as Bifunctional Chelators for Site-Specific Radiolabeling
Förster, C.; Schubert, M.; Pietzsch, H.-J.; Steinbach, J.
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Molecules 16(2011), 5228-5240
DOI: 10.3390/molecules16065228
ISSN: 1420-3049
Cited 10 times in Scopus
Synthesis, characterization and biological evaluation of [188Re(N)(cys∼)(PNP)]+/0 mixed-ligand complexes as prototypes for the development of 188Re(N)-based target-specific radiopharmaceuticals
Thieme, S.; Agostini, S.; Bergmann, R.; Pietzsch, J.; Pietzsch, H.-J.; Carta, D.; Salvarese, N.; Refosco, F.; Bolzati, C.
Involved research facilities
- PET-Center
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Nuclear Medicine and Biology 38(2011), 399-415
DOI: 10.1016/j.nucmedbio.2010.09.006
Cited 13 times in Scopus
Imidazole Containing Bispidine Ligands: Synthesis, Structure and Cu(II)-Complexation
Walther, M.; Matterna, M.; Juran, S.; Fähnemann, S.; Stephan, H.; Kraus, W.; Emmerling, F.
- Zeitschrift für Naturforschung Section B - A Journal of Chemical Sciences 66b(2011), 721-728
A Novel Tetrabranched Neurotensin(8-13) Cyclam Derivative: Synthesis, 64Cu-Labeling and Biological Evaluation
Röhrich, A.; Bergmann, R.; Kretzschmann, A.; Noll, S.; Steinbach, J.; Pietzsch, J.; Stephan, H.
Involved research facilities
- PET-Center
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Journal of Inorganic Biochemistry 105(2011), 821-832
DOI: 10.1016/j.jinorgbio.2011.02.011
Cited 21 times in Scopus
Nanomaterials: applications in cancer imaging and therapy
Barreto, J. A.; O'Malley, W.; Kubeil, M.; Graham, B.; Stephan, H.; Spiccia, L.
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Advanced Materials 23(2011)12, H18-H40
DOI: 10.1002/adma.201190041
Synthesis, structure determination and (radio-) fluorination of novel functionalized phosphanes suitable for the traceless Staudinger ligation
Mamat, C.; Franke, M.; Peppel, T.; Köckerling, M.; Steinbach, J.
Involved research facilities
- PET-Center
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Tetrahedron 67(2011), 4521-4529
DOI: 10.1016/j.tet.2011.04.091
Cited 19 times in Scopus
Synthesis and biological evaluation of new [Tc(N)(PS)]-based mixed-ligand compounds useful in design of target-specific radiopharmaceuticas: the 2-methoxyphenylpiperazine dithiocarbamate derivatives as example
Bolzati, C.; Salvarese, N.; Carta, D.; Refosco, F.; Dolmella, A.; Pietzsch, H.-J.; Bergmann, R.; Bandoli, G.
Involved research facilities
- PET-Center
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Journal of Biological Inorganic Chemistry 16(2011), 137-155
DOI: 10.1007/s00775-010-0712-4
Cited 14 times in Scopus
[18F]1-(3-fluoropropyl)piperazines as model compounds for the radiofluorination of pyrido[2,3-d]pyrimidines
Grosse-Gehling, P.; Wuest, F. R.; Peppel, T.; Köckerling, M.; Mamat, C.
Involved research facilities
- PET-Center
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Radiochimica Acta 99(2011), 365-373
DOI: 10.1524/ract.2011.1834
Cited 8 times in Scopus
Cross-Coupling Reactions as Valuable Tool for the Preparation of PET Radiotracers
Pretze, M.; Große-Gehling, P.; Mamat, C.
Involved research facilities
- PET-Center
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Molecules 16(2011), 1129-1165
DOI: 10.3390/molecules16021129
Cited 44 times in Scopus
2010
Sugar-decorated dendritic nanocarriers: Encapsulation and release of the octahedral rhenium cluster complex [Re6S8(OH)6]4-
Kubeil, M.; Stephan, H.; Pietzsch, H.-J.; Geipel, G.; Appelhans, D.; Voit, B.; Hoffmann, J.; Brutschy, B.; Mironov, Y. V.; Brylev, K. A.; Fedorov, V. E.
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Chemistry - An Asian Journal 5(2010), 2507-2514
DOI: 10.1002/asia.201000284
Cited 32 times in Scopus
Comparison of the stability of Y-90-, Lu-177- and Ga-68- labeled human serum albumin microspheres (DOTA-HSAM)
Wunderlich, G.; Schiller, E.; Bergmann, R.; Pietzsch, H.-J.
Involved research facilities
- PET-Center
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Nuclear Medicine and Biology 37(2010), 861-867
DOI: 10.1016/j.nucmedbio.2010.05.004
Cited 30 times in Scopus
The traceless Staudinger ligation with fluorine-18: a novel and versatile labeling technique for the synthesis of PET-radiotracers
Pretze, M.; Wuest, F.; Peppel, T.; Köckerling, M.; Mamat, C.
Involved research facilities
- PET-Center
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Tetrahedron Letters 51(2010), 6410-6414
DOI: 10.1016/j.tetlet.2010.09.134
Cited 43 times in Scopus
Preparation, 99mTc-labeling and biodistribution studies of a PNA oligomer containing a new ligand derivative of 2,2′-dipicolylamine
Gasser, G.; Jäger, K.; Zenker, M.; Bergmann, R.; Steinbach, J.; Stephan, H.; Metzler-Nolte, N.
Involved research facilities
- PET-Center
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Journal of Inorganic Biochemistry 104(2010), 1133-1140
DOI: 10.1016/j.jinorgbio.2010.06.011
Cited 41 times in Scopus
A novel Dibenzoazacyclooctyne precursor in regioselective Copper-free click chemistry. An innovative 3-step synthesis.
Starke, F.; Walther, M.; Pietzsch, H.-J.
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ARKIVOC (2010), 350-359
ISSN: 1551-7012
Synthesis and Radiofluorination of Iodophenyl Esters as Tool for the Traceless Staudinger Ligation
Pretze, M.; Flemming, A.; Köckerling, M.; Mamat, C.
Involved research facilities
- PET-Center
- Zeitschrift für Naturforschung Section B - A Journal of Chemical Sciences 65(2010), 1128-1136
A new hexanuclear rhenium cluster complex with six terminal acetate ligands: Synthesis, structure, and properties of K4[Re6S8(CH3COO)6]·8H2O
Brylev, K. A.; Mironov, Y. V.; Fedorov, V. E.; Kim, S.-J.; Pietzsch, H.-J.; Stephan, H.; Ito, A.; Kitamura, N.
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Inorganica Chimica Acta 363(2010)11, 2686-2691
DOI: 10.1016/j.ica.2010.04.042
Cited 36 times in Scopus
Novel 99mTc '4 + 1' peptide conjugates: Tuning the biodistribution by variation of coligands
Künstler, J.-U.; Seidel, G.; Bergmann, R.; Gniazdowska, E.; Walther, M.; Schiller, E.; Decristoforo, C.; Stephan, H.; Haubner, R.; Steinbach, J.; Pietzsch, H.-J.
Involved research facilities
- PET-Center
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European Journal of Medicinal Chemistry 45(2010), 3645-3655
DOI: 10.1016/j.ejmech.2010.05.010
Cited 17 times in Scopus
Crystal structure of N-benzyl-4-fluorobenzamide, C14H12FNO, at 173 K
Mamat, C.; Flemming, A.; Köckerling, M.
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Zeitschrift für Kristallographie - New Crystal Structures 225(2010), 345-346
DOI: 10.1524/ncrs.2010.0150
Cited 1 times in Scopus
Efficient preparation of 99mTc(III) 4+1 mixed-ligand complexes for peptide labeling with high specific activity
Künstler, J.-U.; Seidel, G.; Pietzsch, H.-J.
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Applied Radiation and Isotopes 68(2010), 1728-1733
DOI: 10.1016/j.apradiso.2010.04.008
Cited 8 times in Scopus
2009
Recent Application of Click Chemistry for the Synthesis of Radiotracers for Molecular Imaging
Mamat, C.; Ramenda, T.; Wuest, F.
- Mini-Reviews in Organic Chemistry 6(2009), 21-34
NMR Studies and Crystal Structure Determinations of CF3 Group-containing Bicyclic phenolates
Mamat, C.; Reinke, H.; Langer, P.
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Zeitschrift für Naturforschung Section B - A Journal of Chemical Sciences 64(2009)4, 423-426
ISSN: 0932-0776
Synthesis and characterization of rhenium and technetium-99m tricarbonyl complexes bearing the 4-[3-bromophenyl]quinazoline moiety as a biomarker for EGFR-TK imaging
Bourkoula, A.; Paravatou-Petsotas, M.; Papadopoulos, A.; Santos, I.; Pietzsch, H.-J.; Livaniou, E.; Pelecanou, M.; Papadopoulos, M.; Pirmettis, I.
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European Journal of Medicinal Chemistry 44(2009), 4021-4027
DOI: 10.1016/j.ejmech.2009.04.033
Cited 41 times in Scopus
Isomerism in tetrahedral rhenium cluster complexes [Re4Q4(PMe2sub>Ph)4X8]·nCH2Cl2 (Q = Se, X = Br; Q = Te, X = Cl, Br).
Efremova, O. A.; Mironov, Y. V.; Brylev, K. A.; Fedorov, V. E.; Pietzsch, H.-J.; Stephan, H.
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Polyhedron 28(2009), 2973-2976
DOI: 10.1016/j.poly.2009.07.003
Cited 3 times in Scopus
Synthesis of Benzoate-Functionalized Phosphanes as Novel Building Blocks for the Traceless Staudinger Ligation
Mamat, C.; Flemming, A.; Köckerling, M.; Steinbach, J.; Wuest, F.
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Synthesis 19(2009), 3311-3321
DOI: 10.1055/s-0029-1216947
Cited 26 times in Scopus
Radiosynthesis of New [90Y]-DOTA-Based Maleimide Reagents Suitable for the Prelabeling of Thiol-Bearing L-Oligonucleotides and Peptides
Schlesinger, J.; Fischer, C.; Közle, I.; Vonhoff, S.; Klussmann, S.; Bergmann, R.; Pietzsch, H.-J.; Steinbach, J.
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Bioconjugate Chemistry 20(2009), 1340-1348
DOI: 10.1021/bc900095k
Cited 19 times in Scopus
Two Coordination Modes of Bidentate Aminopyrazine Ligands in Cubane-type Cluster Complex Re4Te4Cl8(C4N3H4)4 . 2DMF
Efremova, O. A.; Mironov, Y. V.; Pietzsch, H.-J.; Stephan, H.; Perrin, C.; Fedorov, V. E.
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Journal of Cluster Science 20(2009), 77-81
DOI: 10.1007/s10876-008-0219-0
Cited 2 times in Scopus
The First Octahedral Cluster Complexes With Terminal Formate Ligands: Synthesis, Structure, and Properties of K4[Re6S8(HCOO)6] and Cs4[Re6S8(HCOO)6]
Brylev, K. A.; Mironov, Y. V.; Kozlova, S. G.; Fedorov, V. E.; Kim, S.-J.; Pietzsch, H.-J.; Stephan, H.; Ito, A.; Ishizaka, S.; Kitamura, N.
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Inorganic Chemistry 48(2009), 2309-2315
DOI: 10.1021/ic802178q
Cited 55 times in Scopus
Hexadentate Bispidine Derivatives as Versatile Bifunctional Chelate Agents for Copper(II) Radioisotopes
Juran, S.; Walther, M.; Stephan, H.; Bergmann, R.; Steinbach, J.; Kraus, W.; Emmerling, F.; Comba, P.
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Bioconjugate Chemistry 20(2009), 347-359
DOI: 10.1021/bc800461e
Cited 90 times in Scopus
Validation of 99mTc-labeled "4+1" fatty acids for myocardial metabolism and flow imaging Part 2: Subcellular distribution
Mirtschink, P.; Stehr, S. N.; Walther, M.; Pietzsch, J.; Bergmann, R.; Pietzsch, H.-J.; Weichsel, J.; Pexa, A.; Dieterich, P.; Wunderlich, G.; Binas, B.; Kropp, J.; Deussen, A.
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Nuclear Medicine and Biology 36(2009), 845-852
DOI: 10.1016/j.nucmedbio.2009.06.003
Cited 9 times in Scopus
Validation of 99mTc-labeled "4+1" fatty acids for myocardial metabolism and flow imaging Part 1: Myocardial extraction and biodistribution
Mirtschink, P.; Stehr, S. N.; Walther, M.; Pietzsch, J.; Bergmann, R.; Pietzsch, H.-J.; Weichsel, J.; Pexa, A.; Dieterich, P.; Wunderlich, G.; Binas, B.; Kropp, J.; Deussen, A.
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Nuclear Medicine and Biology 36(2009), 833-843
DOI: 10.1016/j.nucmedbio.2009.06.009
Cited 12 times in Scopus
Synthesis of modified pyrimidine bases and positive impact of the chemically reactive substituents on their in vitro antiproliferative activity
Noll, S.; Kralj, M.; Suman, L.; Stephan, H.; Piantanida, I.
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European Journal of Medicinal Chemistry 44(2009), 1172-1179
DOI: 10.1016/j.ejmech.2008.06.002
Cited 24 times in Scopus
2008
Rhenium and technetium complexes bearing quinazoline derivatives: progress towards a 99mTc biomarker for EGFR-TK imaging
Fernandes, C.; Santos, I. C.; Santos, I.; Pietzsch, H.-J.; Künstler, J.-U.; Kraus, W.; Rey, A.; Margaritis, N.; Bourkoula, A.; Chiotellis, A.; Paravatou-Petsotase, M.; Pirmettis, I.
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Dalton Transactions (2008), 3215-3225
DOI: 10.1039/b802021c
Cited 42 times in Scopus
Enzymatic properties of an ecto-nucleoside triphosphate diphosphohydrolase from Legionella pneumophila; substrate specificity and requirement for virulence
Sansom, F. M.; Riedmaier, P.; Newton, H. J.; Dunstone, M. A.; Müller, C. E.; Stephan, H.; Byres, E.; Beddoe, T.; Rossjohn, J.; Cowan, P. J.; D'Apice, A. J. F.; Robson, S. C.; Hartland, E. L.
- Journal of Biological Chemistry 283(2008)19, 12909-12918
Yttrium-86-labelled human serum albumin microspheres: relation of surface structure with in vivo stability
Schiller, E.; Bergmann, R.; Pietzsch, J.; Noll, B.; Sterger, A.; Johannsen, B.; Wunderlich, G.; Pietzsch, H.-J.
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Nuclear Medicine and Biology 35(2008), 227-232
DOI: 10.1016/j.nucmedbio.2007.10.008
Cited 25 times in Scopus