Publications of Institute of Radiopharmaceutical Cancer Research

322 Publications

2017

Studies of carbon monoxide release from ruthenium(II) bipyridine carbonyl complexes upon UV light exposure
Kubeil, M.ORC; Vernooij, R. R.; Kubeil, C.; Wood, B. R.; Graham, B.; Stephan, H.; Spiccia, L.
Corresponding author: Kubeil, M. HZDR

Preparation of a novel radiotracer targeting the EphB4 receptor via radiofluorination using spiro azetidinium salts as precursor
Wiemer, J.; Steinbach, J.ORC; Pietzsch, J.ORC; Mamat, C.ORC
Corresponding author: Mamat, Constantin

Surface charge and particle size determine the metabolic fate of dendritic polyglycerols
Pant, K.; Pufe, J.; Zarschler, K.; Bergmann, R.; Steinbach, J.; Reimann, S.; Haag, R.; Pietzsch, J.; Stephan, H.ORC
Corresponding author: Stephan, Holger

A novel nanobody-based target module for retargeting of T lymphocytes to EGFR-expressing cancer cells via the modular UniCAR platform
Albert, S.; Arndt, C.; Feldmann, A.; Bergmann, R.; Bachmann, D.; Koristka, S.; Ludwig, F.; Ziller-Walter, P.; Kegler, A.; Gärtner, S.; Schmitz, M.; Ehninger, A.; Cartellieri, M.; Ehninger, G.; Pietzsch, H.-J.; Pietzsch, J.; Steinbach, J.; Bachmann, M.
Corresponding author: Arndt, C. Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Institute of Radiopharmaceutical Cancer Research, Dresden, Germany

A novel tumor pretargeting system based on complementary L-configured oligonucleotides
Schubert, M.; Bergmann, R.; Förster, C.; Sihver, W.; Vonhoff, S.; Klussmann, S.; Bethge, L.; Walther, M.; Schlesinger, J.; Pietzsch, J.; Steinbach, J.; Pietzsch, H.-J.

X-ray Structures of Succinimidyl Halobenzoates
Mamat, C.; Weiss, D.-H.; Köckerling, M.
Corresponding author: Mamat, Constantin
Corresponding author: Köckerling, Martin

Nanoparticles for radiooncology: Mission, vision, challenges
Kunz-Schughart, L. A.; Dubrovska, A.; Peitzsch, C.; Ewe, A.; Aigner, A.; Schellenburg, S.; Muders, M. H.; Hampel, S.; Cirillo, G.; Iemma, F.; Tietze, R.; Alexiou, C.; Stephan, H.ORC; Zarschler, K.; Vittorio, O.; Kavallaris, M.; Parak, W. J.; Mädler, L.; Pokhrel, S.

Zwitterionic Modification of Ultra-Small Iron Oxide Nanoparticles for Reduced Protein Corona Formation
Pombo-Garcia, K.; Rühl, C.; Lam, R.; Ang, C.-S.; Scammells, P. J.; Comba, P.; Spiccia, L.; Graham, B.; Joshi, T.; Stephan, H.ORC

Distribution and kinetics of the Kv1.3-blocking peptide HsTX1[R14A] in experimental rats
Bergmann, R.; Kubeil, M.; Zarschler, K.; Chhabra, S.; Tajhya, R. B.; Beeton, C.; Pennington, M. W.; Bachmann, M.; Norton, R. S.; Stephan, H.ORC
Corresponding author: Stephan, Holger

In vivo examination of an injectable hydrogel system crosslinked by peptide-oligosaccharide interaction in immunocompetent nude mice
Tondera, C.; Wieduwild, R.; Röder, E.; Werner, C.; Zhang, Y.; Pietzsch, J.ORC

Retargeting of T lymphocytes to PSCA- or PSMA positive prostate cancer cells using the novel modular chimeric antigen receptor platform technology “UniCAR”
Feldmann, A.; Arndt, C.; Bergmann, R.; Loff, S.; Cartellieri, M.; Bachmann, D.; Aliperta, R.; Hetzenecker, M.; Ludwig, F.; Albert, S.; Ziller-Walter, P.; Kegler, A.; Koristka, S.; Gärtner, S.; Schmitz, M.; Ehninger, A.; Ehninger, G.; Pietzsch, J.; Steinbach, J.; Bachmann, M.
Corresponding author: Koristka, S.
Corresponding author: Bachmann, M.

The Why and How of Amino Acid Analytics in Cancer Diagnostics and Therapy
Manig, F.; Kuhne, K.; von Neubeck, C.; Schwarzenbolz, U.; Yu, Z.; Kessler, B. M.; Pietzsch, J.; Kunz-Schughart, L. A.

Substrate-dependence of competitive nucleotide pyrophosphatase / phosphodiesterase1 (NPP1)
Lee, S.-Y.; Sarkar, S.; Bhattarai, S.; Namasivayam, V.; de Jonghe, S.; Stephan, H.ORC; Herdewijn, P.; El-Tayeb, A.; Müller, C. E.

Human endothelial cell models in biomaterial research
Hauser, S.; Jung, F.; Pietzsch, J.ORC

Radiolabelled polymeric materials for imaging and treatment of cancer: Quo Vadis?
Pant, K.; Sedláček, O.; Nadar, R. A.; Hrubý, M.; Stephan, H.ORC

Insights into binding of S100 proteins to scavenger receptors: class B scavenger receptor CD36 binds S100A12 with high affinity
Tondera, C.; Laube, M.; Pietzsch, J.
Corresponding author: Pietzsch, J.

A fluorescence anisotropy-based assay for determining the activity of tissue transglutaminase
Hauser, C.; Wodtke, R.; Löser, R.; Pietsch, M.

2016

New insights into the pretargeting approach to image and treat tumours
Patra, M.; Zarschler, K.; Pietzsch, H.-J.; Stephan, H.; Gasser, G.
Corresponding author: Zarschler, Kristof Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research
Corresponding author: Pietzsch, Hans-Jürgen Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research
Corresponding author: Stephan, Holger Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research

Melanoma targeting with [99mTc(N)(PNP3)]-labeled α-melanocyte stimulating hormone peptide analogs: Effects of cyclization on the radiopharmaceutical properties
Carta, D.; Salvarese, N.; Morellato, N.; Gao, F.; Sihver, W.; Pietzsch, H.-J.; Biondi, B.; Ruzza, P.; Refosco, F.; Carpanese, D.; Rosato, A.; Bolzati, C.

Development of a F-18-labeled Diaryl-Substituted Dihydropyrrolo[3,2,1-hi]indole as Potential Probe for Functional Imaging of Cyclooxygenase-2 with PET
Gassner, C.; Neuber, C.; Laube, M.; Bergmann, R.; Kniess, T.; Pietzsch, J.ORC

Gelatin-based hydrogel degradation and tissue interaction in vivo: insights from multimodal preclinical imaging in immunocompetent nude mice
Tondera, C.; Ullm, S.; Krüger-Genge, A.; Jung, F.; Neffe, A. T.; Lendlein, A.; Klopfleisch, R.; Steinbach, J.; Neuber, C.; Pietzsch, J.
Corresponding author: Pietzsch, J.

Zwitterionic polymer-coated ultrasmall superparamagnetic iron oxide nanoparticles with low protein interaction and high biocompatibility
Pombo-García, K.; Weiss, S.; Zarschler, K.; Ang, C.-S.; Hübner, R.; Pufe, J.; Meister, S.; Seidel, J.; Pietzsch, J.; Spiccia, L.; Stephan, H.ORC; Graham, B.

Extracellular S100A4 affects endothelial cell integrity and stimulates transmigratory behavior of human A375 melanoma cells
Herwig, N.; Belter, B.; Pietzsch, J.

Polyglycerol-Based Copper Chelators for the Transport and Release of Copper Ions in Biological Environments
Albrecht, R.; Fehse, S.; Pant, K.; Nowag, S.; Stephan, H.; Haag, R.; Tzschucke, C. C.

Direct and Auger electron-induced, single- and double-strand breaks on plasmid DNA caused by 99mTc-labeled pyrene derivatives and the effect of bonding distance
Reissig, F.; Mamat, C.; Steinbach, J.; Pietzsch, H.-J.; Freudenberg, R.; Kotzerke, J.; Wunderlich, G.

Synthesis and kinetic characterisation of water-soluble fluorogenic acyl donors for transglutaminase 2
Wodtke, R.; Schramm, G.; Pietzsch, J.; Pietsch, M.; Löser, R.

Multimodal Somatostatin Receptor Theranostics Using [64Cu]Cu-/[177Lu]Lu-DOTA-(Tyr3)octreotate and AN-238 in a Mouse Pheochromocytoma Model.
Ullrich, M.; Bergmann, R.; Peitzsch, M.; Zenker, E.; Cartellieri, M.; Bachmann, M.; Ehrhart-Bornstein, M.; Block, N.; Schally, A.; Eisenhofer, G.; Bornstein, S.; Pietzsch, J.; Ziegler, C.

Development of antioxidant COX-2 inhibitors as radioprotective agents for radiation therapy – a hypothesis-driven review
Laube, M.; Kniess, T.; Pietzsch, J.
Corresponding author: Laube, M.
Corresponding author: Pietzsch, J.

Ultrasmall inorganic nanoparticles: state-of-the-art and perspectives for biomedical applications
Zarschler, K.; Rocks, L.; Licciardello, N.; Boselli, L.; Polo, E.; Pombo Garcia, K.; de Cola, L.; Stephan, H.; Dawson, K. A.

5-Chloro-1-phenylpentan-1-one
Bechmann, N.; Kniess, T.; Pietzsch, J.; König, J.; Köckerling, M.

Nuclear and optical dual-labelled imaging agents: Design and challenges
Singh, G.; Gott, M.; Pietzsch, H.-J.; Stephan, H.ORC
  • Open Access LogoNuklearmedizin 55(2016)2, 41-50

Synthesis, dynamic NMR characterization and XRD studies of novel N,N’-substituted piperazines for bioorthogonal labeling
Mamat, C.; Pretze, M.; Gott, M.; Köckerling, M.

The Radiochemical and radiopharmaceutical applications of radium
Gott, M.; Steinbach, J.; Mamat, C.
Corresponding author: Gott, Matthew

177Lu-labelled macrocyclic bisphosphonates for targeting bone metastasis in cancer treatment
Bergmann, R.; Meckel, M.; Kubicek, V.; Pietzsch, J.; Steinbach, J.; Hermann, P.; Rösch, F.
Corresponding author: Bergmann, Ralf

Radiopharmacological characterization of 64Cu-labeled α-MSH analogs for potential use in imaging of malignant melanoma
Gao, F.; Sihver, W.; Jurischka, C.; Bergmann, R.; Haase-Kohn, C.; Belter, B.; Steinbach, J.; Carta, D.; Bolzati, C.; Calderan, A.; Pietzsch, J.; Pietzsch, H.-J.
Corresponding author: Sihver, Wiebke

Interaction of extracellular S100A4 with RAGE prompts prometastatic activation of A375 melanoma cells
Herwig, N.; Belter, B.; Wolf, S.; Haase-Kohn, C.; Pietzsch, J.
Corresponding author: Pietzsch, Jens

2015

Protective effects of 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitors on oxidative modification of human low density lipoproteins in vitro
Pietzsch, J.; Laube, M.; Bechmann, N.; Pietzsch, F.-J.; Kniess, T.

Controlled immobilization of His-tagged proteins for protein-ligand interaction experiments using Ni2+-NTA layer on glass surfaces
Cherkouk, C.; Rebohle, L.; Lenk, J.; Keller, A.; Ou, X.; Laubec, M.; Neuber, C.; Haase-Kohn, C.; Pietzsch, J.; Skorupa, W.

Cyclam Derivatives with a Bis(phosphinate) or a Phosphinato−Phosphonate Pendant Arm: Ligands for Fast and Efficient Copper(II) Complexation for Nuclear Medical Applications
David, T.; Kubićek, V.; Gutten, O.; Lubal, P.; Kotek, J.; Pietzsch, H.-J.; Rulíśek, L.; Hermann, P.

Influence of irradiation on release of endothelial microparticles (EMP) in vitro
Neuber, C.; Pufe, J.; Pietzsch, J.

18F-Labeled 1,4-Dioxa-8-azaspiro[4.5]decane Derivative: Synthesis and Biological Evaluation of a σ1 Receptor Radioligand with Low Lipophilicity as Potent Tumor Imaging Agent
Xie, F.; Bergmann, R.; Kniess, T.; Deuther-Conrad, W.; Mamat, C.; Neuber, C.; Liu, B.; Steinbach, J.; Brust, P.; Pietzsch, J.; Jia, H.

Novel (pyrazolyl)benzenesulfonamides with a nitric oxide-releasing moiety as selective cyclooxygenase-2 inhibitors
Bechmann, N.; Kniess, T.; Köckerling, M.; Pigorsch, A.; Steinbach, J.; Pietzsch, J.

Methods to increase the metabolic stability of 18F-radiotracers
Kuchar, M.; Mamat, C.

In vivo Demonstration of an Active Tumor Pretargeting Approach with Peptide Nucleic Acid Bioconjugates as Complementary System
Leonidova, A.; Foerster, C.; Zarschler, K.; Schubert, M.; Pietzsch, H.-J.; Steinbach, J.; Bergmann, R.; Metzler-Nolte, N.; Stephan, H.; Gasser, G.

Cysteine cathepsins: their role in tumor progression and recent trends in the development of imaging probes
Löser, R.; Pietzsch, J.

Copper(II) cyclam complexes with N-propionic acid pendant arms
Kubeil, M.; Zarschler, K.; Pietzsch, J.; Kraus, W.; Comba, P.; Stephan, H.

Novel indole-based sigma-2 receptor ligands: synthesis, structure–affinity relationship and antiproliferative activity
Xie, F.; Kniess, T.; Neuber, C.; Deuther-Conrad, W.; Mamat, C.; Liebermann, Brain P.; Liu, B.; Mach, Robert H.; Brust, P.; Steinbach, J.; Pietzsch, J.; Jia, H.
Corresponding author: Kniess, Torsten

Synthesis and Molecular Structure of 2-(Diphenylphosphano) phenyl Benzoate Borane Adduct
Mamat, C.; Köckerling, M.

CuII-selective bispidine–dye conjugates
Bronx, D.; Comba, P.; Herten, D.-P.; Kimmle, E.; Morgen, M.; Rühl, Carmen L.; Rybina, A.; Stephan, H.; Storch, G.; Wadepohl, H.

Synthesis and Biodistribution Studies of 3H- and 64Cu-labeled Dendritic Polyglycerol and Dendritic Polyglycerol Sulfate
Pant, K.; Gröger, D.; Bergmann, R.; Pietzsch, J.; Steinbach, J.; Graham, B.; Spiccia, L.; Berthon, F.; Czarny, B.; Devel, L.; Dive, V.; Stephan, H.; Haag, R.

Development of indazolylpyrimidine derivatives as high-affine EphB4 receptor ligands and potential PET-radiotracers
Ebert, K.; Wiemer, J.; Caballero, J.; Köckerling, M.; Steinbach, J.; Pietzsch, J.; Mamat, C.

Reduced pulmonary blood flow in regions of injury 2 hours after acid aspiration in rats
Richter, T.; Bergmann, R.; Musch, G.; Pietzsch, G.; Koch, T.

Optical imaging of COX-2: Studies on an autofluorescent 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitor.
Tondera, C.; Ullm, S.; Laube, M.; Meister, S.; Neuber, C.; Mosch, B.; Kniess, T.; Pietzsch, J.

Theranostic mercury: 197(m)Hg with high specific activity for imaging and therapy
Walther, M.; Preusche, S.; Bartel, S.; Wunderlich, G.; Freudenberg, R.; Steinbach, J.; Pietzsch, H.-J.

Cyclopeptides containing the DEKS motif as conformationally restricted collagen telopeptide analogues: synthesis and conformational analysis
Wodtke, R.; Ruiz-Gómez, G.; Kuchar, M.; Pisabarro, M. Teresa; Novotná, P.; Urbanová, M.; Steinbach, J.; Pietzsch, J.; Löser, R.

Bifunctional Cyclam-Based Ligands with Phosphorus Acid Pendant Moieties for Radiocopper Separation – Thermodynamic and Kinetic Studies
Paúrová, M.; Havlíčková, J.; Pospíšilová, A.; Vetrík, M.; Císařová, I.; Stephan, H.; Pietzsch, H.-J.; Hrubý, M.; Hermann, P.; Kotek, J.

Diaryl-substituted (dihydro)pyrrolo[3,2,1-hi]indoles, a class of potent COX-2 inhibitors with tricyclic core structure
Laube, M.; Gassner, C.; Sharma, S. K.; Günther, R.; Pigorsch, A.; König, J.; Köckerling, M.; Wuest, F.; Pietzsch, J.; Kniess, T.

Polyoxometalates - potent and selective ecto-nucleotidase inhibitors
Lee, S.-Y.; Fiene, A.; Li, W.; Hank, T.; Brylev, K.; Fedovrov, V.; Lecka, J.; Haider, A.; Pietzsch, H.-J.; Zimmermann, H.; Sévigny, J.; Kortz, U.; Stephan, H.; Müller, C. E.

Effects of pulmonary acid aspiration on the regional pulmonary blood flow within the first hour after injury: an observational study in rats
Richter, T.; Bergmann, R.; Pietzsch, J.; Mueller, M. P.; Koch, T.

Evaluation of Novel Fluorescence Probes for Conjugation Purposes Using the Traceless Staudinger Ligation
Wodtke, R.; König, J.; Pigorsch, A.; Köckerling, M.; Mamat, C.

2014

Preparation of 4-Halobenzoate Containing Phosphane Based Building Blocks for Labeling Reactions Using the Traceless Staudinger Ligation
Mamat, C.; Köckerling, M.

X-ray structure of 2-(diphenylphosphano)phenyl-4-(hydroxymethyl)benzoate
Mamat, C.; Flemming, A.; Köckerling, M.

Organotypical vascular model for characterization of radioprotective compounds: Studies on antioxidant 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitors
Ullm, S.; Laube, M.; Bechmann, N.; Knieß, T.; Pietzsch, J.

Characterization of circulating microparticle-associated CD39 family ecto-nucleotidases in human plasma
Jiang, Z. G.; Wu, Y.; Csizmadia, E.; Feldbrügge, L.; Enjyoji, K.; Tigges, J.; Toxavidis, V.; Stephan, H.; Müller, C. E.; Mcknight, C. J.; Moss, A.; Robson, S. C.

The Ti7-Containing, Tetrahedral 36-Tungsto-4-Arsenate(III)[Ti6(TiO6)(AsW9O33)4]20-
Wang, K.-Y.; Bassil, B. S.; Lin, Z. G.; Haider, A.; Cao, J.; Stephan, H.; Viehweger, K.; Kortz, U.

Bispidines for dual imaging
Stephan, H.; Walther, M.; Fähnemann, S.; Ceroni, P.; Molloy, J.; Bergamini, G.; Heisig, F.; Müller, C. E.; Kraus, W.; Comba, P.

2,3-Diaryl-substituted indole based COX-2 inhibitors as leads for imaging tracer development
Laube, M.; Tondera, C.; Sharma, S. K.; Bechmann, N.; Pietzsch, F.-J.; Pigorsch, A.; Köckerling, M.; Wuest, F.; Pietzsch, J.; Kniess, T.

In Vivo Fluorescence Imaging and Urinary Monoamines as Surrogate Biomarkers of Disease Progression in a Mouse Model of Pheochromocytoma
Ullrich, M.; Bergmann, R.; Peitzsch, M.; Cartellieri, M.; Quin, N.; Erhart-Bornstein, M.; Block, N. L.; Schalley, A. V.; Pietzsch, J.; Eisenhofer, G.; Bornstein, S. R.; Ziegler, C. G.

Biocompatibility and inflammatory response in vitro and in vivo to gelatin-based biomaterials with tailorable elastic properties
Ullm, S.; Krüger, A.; Tondera, C.; Gebauer, Tim P.; Neffe, Axel T.; Lendlein, A.; Jung, F.; Pietzsch, J.

Zwitterionic-Coated "Stealth" Nanoparticles for Biomedical Applications: Recent Advances in Countering Biomolecular Corona Formation and Uptake by the Mononuclear Phagocyte System
Pombo Garcia, K.; Zarschler, K.; Barbaro, L.; Barreto, J. A.; O'Malley, W.; Spiccia, L.; Stephan, H.; Graham, B.

Assessment of the best N3− donors in preparation of [M(N)(PNP)]-based (M = 99mTc-; 188Re) target-specific radiopharmaceuticals: Comparison among succinic dihydrazide (SDH), N-methyl-S-methyl dithiocarbazate (HDTCZ) and PEGylated N-methyl-S-methyl dithiocarbazate (HO2C-PEG600-DTCZ)
Carta, D.; Jentschel, C.; Thieme, S.; Salvarese, N.; Morellato, N.; Refosco, F.; Ruzza, P.; Bergmann, R.; Pietzsch, H.-J.; Bolzati, C.

Bispidine dioxotetraaza macrocycles: a new class of bispidines for 64Cu PET imaging
Comba, P.; Kubeil, M.; Pietzsch, J.; Rudolf, H.; Stephan, H.; Zarschler, K.

Radiofluorination and first radiopharmacological characterization of a SWLAY peptide-based ligand targeting EphA2
Pretze, M.; Mosch, B.; Bergmann, R.; Steinbach, J.; Pietzsch, J.; Mamat, C.

EGF receptor-targeting peptide conjugate incorporating a near-IR fluorescent dye and a novel 1,4,7-triazacyclononane-based 64Cu(II) chelator assembled via click chemistry
Viehweger, K.; Barbaro, L.; Pombo García, K.; Joshi, T.; Geipel, G.; Steinbach, J.; Stephan, H.; Spiccia, L.; Graham, B.

Diagnostic nanoparticle targeting of the EGF-receptor in complex biological conditions using single-domain antibodies
Zarschler, K.; Prapainop, K.; Mahon, E.; Rocks, L.; Bramini, M.; Kelly, P.; Stephan, H.; Dawson, K. A.

Cytotoxic properties of radionuclide-conjugated Cetuximab without and in combination with external irradiation in head and neck cancer cells in vitro
Eke, I.; Ingargiola, M.; Förster, C.; Kunz-Schughart, L.; Baumann, M.; Runge, R.; Freudenberg, R.; Kotzerke, J.; Heldt, J.; Pietzsch, H.; Steinbach, J.; Cordes, N.

Metastatic potential of B16-F10 melanoma cells is enhanced by extracellular S100A4 derived from RAW264.7 macrophages
Haase-Kohn, C.; Wolf, S.; Herwig, N.; Mosch, B.; Pietzsch, J.

Visualizing inflammation activity in rheumatoid arthritis with Tc-99 m Anti-CD4-mAb fragment scintigraphy
Steinhoff, K.; Pierer, M.; Siegert, J.; Pigla, U.; Laub, R.; Hesse, S.; Seidel, W.; Sorger, D.; Seese, A.; Künstler, J.-U.; Pietzsch, H.-J.; Lincke, T.; Rullmann, M.; Emmrich, F.; Sabri, O.

Radiolabeled anti-EGFR-antibody improves local tumor control after external beam radiotherapy and offers theragnostic potential
Koi, L.; Bergmann, R.; Brüchner, K.; Pietzsch, J.; Pietzsch, H.-J.; Krause, M.; Steinbach, J.; Zips, D.; Baumann, M.

Establishment of two complementary in vitro assays for radiocopper complexes achieving reliable and comparable evaluation of in vivo stability
Zarschler, K.; Kubeil, M.; Stephan, H.

Radiolabeled cetuximab conjugates for EGFR targeted cancer diagnostics and therapy
Sihver, W.; Pietzsch, J.; Krause, M.; Baumann, M.; Steinbach, J.; Pietzsch, H. J.

2013

Pulmonary Blood Flow Increases in Damaged Regions Directly after Acid Aspiration in Rats
Richter, T.; Bergmann, R.; Knels, L.; Hofheinz, F.; Kasper, M.; Deile, M.; Pietzsch, J.; Ragaller, M.; Koch, T.

Regioselective Synthesis of Trichloromethyl-Substituted Salicylates and Cyclohexenones by One-Pot Cyclizations of 1,3-Bis(trimethylsilyloxy)buta-1,3-dienes
Reimann, S.; Bunescu, A.; Petrosyana, A.; Sharif, M.; Erfle, S.; Mamat, C.; Ghochikyan, Tariel V.; Saghyan, Ashot S.; Spannenberg, A.; Villinger, A.; Langer, P.

High-yield production of functional soluble single-domain antibodies in the cytoplasm of Escherichia coli
Zarschler, K.; Witecy, S.; Kapplusch, F.; Foerster, C.; Stephan, H.

Synthesis and radiopharmacological evaluation of 64Cu-labeled bombesin analogs featuring a bis(2-pyridylmethyl) 1,4,7-triazacyclononane chelator
Bergmann, R.; Ruffani, A.; Graham, B.; Spiccia, L.; Steinbach, J.; Pietzsch, J.; Stephan, H.

Design, synthesis, characterisation and in vitro studies of hydrophilic, colloidally stable, 64Cu(II)-labelled, ultra-small iron oxide nanoparticles in a range of human cell lines
Pombo Garcia, K.; Zarschler, K.; Barreto, J. A.; Hesse, J.; Spiccia, L.; Graham, B.; Stephan, H.

Tissue transglutaminase: an emerging target for therapy and imaging
Pietsch, M.; Wodtke, R.; Pietzsch, J.; Löser, R.

Quantitative Structure Property Relationship of logP for Radiopharmaceutical Technetium and Rhenium Complexes by using Molecular Dynamics Calculations
Yoshizuka, K.; Pietzsch, H.-J.; Seifert, S.; Stephan, H.
  • Open Access LogoSolvent Extraction Research and Development 20(2013), 15-27

Recent Trends in Bioorthogonal Click-Radiolabeling Reactions Using Fluorine-18
Pretze, M.; Pietzsch, D.; Mamat, C.

Optimization of Pentadentate Bispidines as Bifunctional Chelators for 64Cu Positron Emission Tomography (PET)
Comba, P.; Hunoldt, S.; Morgen, M.; Pietzsch, J.; Stephan, H.; Wadepohl, H.

The computation of lipophilicities of 64Cu PET systems based on a novel approach for fluctuating charges
Comba, P.; Martin, B.; Sanyal, A.; Stephan, H.

Condensation of the dianion of ethyl acetoacetate with perfluoroalkyl iodides. Application to the synthesis of 3-perfluoroalkylsalicylic acids
Mamat, C.; Langer, P.

Automated preparation of [18F]AFP and [18F]BFP: Two novel bifunctional 18F-labeling building blocks for Huisgen-click
Pretze, M.; Mamat, C.

An Efficient Bioorthogonal Strategy Using CuAAC Click Chemistry for Radiofluorinations of SNEW Peptides and the Role of Copper Depletion
Pretze, M.; Kuchar, M.; Bergmann, R.; Steinbach, J.; Pietzsch, J.; Mamat, C.

Design and Development of 99mTc-‘4 + 1’-Labeled Dextran-Mannose Derivatives as Potential Radiopharmaceuticals for Sentinel Lymph Node Detection
Giglio, J.; Fernandez, S.; Jentschel, C.; Pietzsch, H.-J.; Papadopoulos, M.; Pelecanou, M.; Pirmettis, I.; Paolino, A.; Rey, A.

Synthesis and radiopharmacological characterisation of a fluorine-18 labelled azadipeptide nitrile as potential PET Tracer for in vivo imaging of cysteine cathepsins
Löser, R.; Bergmann, R.; Frizler, M.; Mosch, B.; Dombrowski, L.; Kuchar, M.; Steinbach, J.; Gütschow, M.; Pietzsch, J.

Recent trends in malignant melanoma biomarker research
Pietzsch, J.; Tandler, N.; Mosch, B.
  • Clinical Laboratory International 37(2013), 6-8

Anti-tumor effects of peptide analogues targeting neuropeptide hormone receptors on mouse pheochromocytoma cells
Ziegler, C. G.; Eisenhofer, G.; Schally, A. V.; Gebauer, L.; Gondek, K.; Ullrich, M.; Qin, N.; Bergmann, R.; Pietzsch, J.; Ehrhart-Bornstein, M.; Bornstein, S. R.

Dendrimers as Nb3+ ligands: effect of generation on the efficiency of the sensitized lanthanide emission
Pillai, Z. S.; Ceroni, P.; Kubeil, M.; Heldt, J.-M.; Stephan, H.; Bergamini, G.

Radiolabeled COX-2 inhibitors for non-invasive visualization of COX-2 expression and activity - a critical update
Laube, M.; Kniess, T.; Pietzsch, J.

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