Publications of Institute of Radiopharmaceutical Cancer Research

407 Publications

2008

Expression, purification and fluorine-18 radiolabeling of recombinant S100 proteins - potential probes for molecular imaging of receptor for advanced glycation endproducts (RAGE) in vivo

Hoppmann, S.; Haase, C.; Richter, S.; Pietzsch, J.


Glycoxidation of low-density lipoprotein in impaired glucose tolerance: implications for the pathogenesis of diabetic vascular disease

Kopprasch, S.; Graessler, J.; Bornstein, S. R.; Pietzsch, J.

  • Vascular Disease Prevention 5(2008), 24-28
    ISSN: 1567-2700

Localized proton magnetic resonance spectroscopy of lipids in adipose tissue at high spatial resolution in mice in vivo

Strobel, K.; van den Hoff, J.; Pietzsch, J.


Modified “4+1” Mixed Ligand Technetium Labeled Fatty Acids for Myocardial Imaging: Evaluation of Myocardial Uptake and Biodistribution

Mirtschink, P.; Stehr, S. N.; Pietzsch, H.-J.; Bergmann, R.; Pietzsch, J.; Wunderlich, G.; Heintz, A. C.; Kropp, J.; Spies, H.; Kraus, W.; Deussen, A.; Walther, M.


Practical experiences with the synthesis of [11C]CH3 trough gas phase iodination reaction using a TRACERlabFXC synthesis module

Knieß, T.; Rode, K.; Wüst, F.


2007

Experimental Evaluation of Functional Imaging for Radiotherapy

Zips, D.; Yaromina, A.; Schütze, C.; Wüllrich, K.; Krause, M.; Krause, M.; Hessel, F.; Eicheler, W.; Dörfler, A.; Brüchner, K.; Menegakis, A.; Zhou, X.; Bergmann, R.; van den Hoff, J.; Beuthien-Baumann, B.; Baumann, M.


Factors influencing the formation of small dense low-density lipoprotein particles in dependence on the presence of the metabolic syndrome and on the degree of glucose intolerance

Julius, U.; Dittrich, M.; Pietzsch, J.


Myocardial uptake and biodistribution of newly designed technetium-labelled fatty acid analogues

Heintz, A. C.; Jung, C. M.; Stehr, S. N.; Mirtschink, P.; Walther, M.; Pietzsch, J.; Bergmann, R.; Pietzsch, H.-J.; Spies, H.; Wunderlich, G.; Kropp, J.; Deussen, A.

  • Nuclear Medicine Communications 28(2007)8, 637-647
    ISSN: 0143-3636

Experimental hypoxia is a potent stimulus for radiotracer uptake in vitro: Comparison of different tumor cells and primary endothelial cells

Oswald, J.; Treite, F.; Haase, C.; Kampfrath, T.; Mäding, P.; Schwenzer, B.; Bergmann, R.; Pietzsch, J.


Effect of increase of radiation dose on local control relates to pre-treatment FDG uptake in FaDu tumours in nude mice

Schütze, C.; Bergmann, R.; Yaromina, A.; Hessel, F.; Kotzerke, J.; Steinbach, J.; Baumann, M.; Beuthien-Baumann, B.


[18F]FBAM and [18F]FBOM: Novel Thiol-reactive prosthetic groups derived from 4-[18F]fluorobenzaldehyde

Vogler, L.; Berndt, M.; Pietzsch, J.; Wüst, F.

  • Lecture (Conference)
    14th Workshop der International Isotope Society, 21.-22.06.2007, Bad Soden, Germany
  • Journal of Labelled Compounds and Radiopharmaceuticals 50(2007), 1276-1286

L-Type Amino Acid Transporters LAT1 and LAT4 in Cancer: Uptake of 3-O- Methyl-6-18F-Fluoro-L-Dopa (18F-OMFD) in Human Adenocarcinoma and Squamous Cell Carcinoma in vitro and in vivo

Haase, C.; Bergmann, R.; Füchtner, F.; Hoepping, A.; Pietzsch, J.


Glycoxidised LDL isolated from subjects with impaired glucose tolerance increases CD36 and peroxisome proliferator-activator receptor gamma gene expression in macrophages

Graessler, J.; Pietzsch, J.; Westendorf, T.; Julius, U.; Bornstein, S. R.; Kopprasch, S.


Very stable 188Re-S4 chelates for labelling biomolecules, prepared with highly concentrated perrhenate eluates

Seifert, S.; Jentschel, C.; Bergmann, R.; Pietzsch, H.-J.; Wunderlich, G.; Kotzerke, J.; Steinbach, J.

  • Nuklearmedizin 5(2007), 181-184
    ISSN: 0029-5566

Lipid transfer protein activities in subjects with impaired glucose tolerance

Julius, U.; Jauhiainen, M.; Ehnholm, C.; Pietzsch, J.

  • Clinical Chemistry and Laboratory Medicine 45(2007)2, 237-243
    ISSN: 1434-6621

Synthesis of 18F-labeled neurotensin(8-13) via copper-mediated 1,3-dipolar [3+2]cycloaddition reaction

Ramenda, T.; Bergmann, R.; Wüst, F.

  • Letters in Drug Design & Discovery 4(2007)4, 279-285
    ISSN: 1570-1808

Labeling of low-density lipoproteins using the 18F-labeled thiol-reactive reagent N-[6-(4-[18F]fluorobenzylidene)aminooxyhexyl]maleimide [18F]FBAM

Berndt, M.; Pietzsch, J.; Wüst, F.


Radiolabelling of multimeric neurotensin(8-13) analogues with the short-lived positron emitter fluorine-18

Hultsch, C.; Berndt, M.; Bergmann, R.; Wüst, F.


Synthesis of 18F-labelled stilbenes from 4-[18F]fluorobenzaldehyde using the Horner-Wadsworth-Emmons reaction

Gester, S.; Pietzsch, J.; Wüst, F.


Synthesis and radiopharmacological characterization of [11C]AL-438 as a nonsteroidal ligand for imaging brain glucocorticoid receptors

Wüst, F.; Knieß, T.; Bergmann, R.; Henry, B.; Pietzsch, J.

  • Bioorganic & Medicinal Chemistry Letters 17(2007), 4035-4039

Synthesis and radiopharmacological characterization of 2β-carbo-2’-[18F]fluoroethoxy-3β-(4-bromo-phenyl)tropane ([18F]MCL-322) as a potential PET radiotracer for imaging the dopamine transporter (DAT)

Wüst, F.; Berndt, M.; Strobel, K.; van den Hoff, J.; Peng, X.; Neumeyer, J. L.; Bergmann, R.


Synthesis and biological evaluation of a new type of 99mTechnetium-labeled fatty acid for myocardial metabolism imaging

Walther, M.; Jung, C.; Bergmann, R.; Pietzsch, J.; Rode, K.; Fahmy, K.; Mirtschink, P.; Stehr, S.; Heintz, A.; Wunderlich, G.; Kraus, W.; Pietzsch, H.-J.; Kropp, J.; Deussen, A.; Spies, H.

  • Bioconjugate Chemistry 18(2007), 216-230
    ISSN: 10.1021/bc0601222

2006

Neurotensin Receptors in Adeno- and Squamous Cell Carcinoma

Haase, C.; Bergmann, R.; Oswald, J.; Zips, D.; Pietzsch, J.

  • Open Access Logo Anticancer Research 26(2006), 3527-3534

Biodistribution and catabolism of 18F-labeled N-epsilon-fructoselysine as a model of Amadori products

Hultsch, C.; Hellwig, M.; Pawelke, B.; Bergmann, R.; Rode, K.; Pietzsch, J.; Krause, R.; Henle, T.


Fluorescein-labeled stable neurotensin derivatives

Maes, V.; Hultsch, C.; Kohl, S.; Bergmann, R.; Hanke, T.; Tourwé, D.

  • Journal of Peptide Science 12(2006), 505-508

Synthesis and evaluation of novel multimeric neurotensin(8-13) analogs

Hultsch, C.; Pawelke, B.; Bergmann, R.; Wüst, F.

  • Bioorganic & Medicinal Chemistry 14(2006)17, 5913-5920

Preparation and Biological Characterization of Isomeric 188Re(V) Oxocomplexes with Tetradentate S4 Ligands Derived from DMSA for Labeling of Biomolecules

Seifert, S.; Heinrich, T.; Jentschel, C.; Smuda, C.; Bergmann, R.; Pietzsch, H.-J.


Chitosan-encapsulated Keggin anion [Ti2W10PO40]7-: Synthesis, characterization and cellular uptake studies

Meißner, T.; Bergmann, R.; Oswald, J.; Rode, K.; Richter, W.; Zänker, H.; Kraus, W.; Emmerling, F.; Reck, G.; Stephan, H.


Synthesis and Radiopharmacological Characterisation of 86Y- and 68Ga-Labelled L-RNA Oligonucleotides as Molecular Probes for Positron Emission Tomography (PET)

Schlesinger, J.; Bergmann, R.; Klussmann, S.; Wüst, F.

  • Letters in Drug Design & Discovery 3(2006)5, 330-335

[11C]SMe-ADAM, an imaging agent for the brain serotonin transporter: Synthesis, pharmacological characterization and microPET studies in rats

Zessin, J.; Deuther-Conrad, W.; Kretzschmar, M.; Wüst, F.; Pawelke, B.; Brust, P.; Steinbach, J.; Bergmann, R.

  • Nuclear Medicine and Biology 33(2006)1, 53-63

2005

Positron emission tomography in food sciences

Pietzsch, J.; van den Hoff, J.


Small animal positron emission tomography in food sciences

Bergmann, R.; Pietzsch, J.


Biodistribution and catabolism of 18F-labelled isopeptide N (varepsilon)-(gamma-glutamyl)-L-lysine

Hultsch, C.; Bergmann, R.; Pawelke, B.; Pietzsch, J.; Wüst, F.; Johannsen, B.; Henle, T.


Catabolism of native and oxidized low density lipoproteins (LDL): in vivo insights from small animal positron emission tomography studies

Pietzsch, J.; Bergmann, R.; Wüst, F.; Pawelke, B.; Hultsch, C.; van den Hoff, J.


Glucose-Induced Enhancement of Hemin-Catalyzed LDL Oxidation In Vitro and In Vivo

Julius, U.; Pietzsch, J.

  • Antioxidants and Redox Signaling 7(2005)11-12, 1507-1512

Pathological consequenses of systemic oxidative stress and dyslipidemia in impaired glucose tolerance and diabetes mellitus

Kopprasch, S.; Grässler, J.; Pietzsch, J.

  • Trends in Cell & Molecular Biology 1(2005), 1-14

In vivo metabolism of oxidized low density lipoproteins: Insights from small animal positron emission tomography (PET) studies

Pietzsch, J.; Bergmann, R.; Wüst, F.; van den Hoff, J.

  • Recent Research Developments in Molecular & Cellular Biochemistry 2(2005), 153-177

Synthesis and biodistribution of an 18F-labelled resveratrol derivative for small animal positron emission tomography (PET)

Gester, S.; Wüst, F.; Pawelke, B.; Bergmann, R.; Pietzsch, J.


Dramatic effect of the tridentate ligand on the stability of Tc-99m "3+1" oxo complexes bearing arylpiperazine derivatives

Fernandes, C.; Correia, D. G.; Gano, L.; Santos, I.; Seifert, S.; Syhre, R.; Bergmann, R.; Spies, H.

  • Bioconjugate Chemistry 16(2005)3, 660-668
    ISSN: 1043-1802

Synthesis and radiopharmacological evaluation of 2´-(4-fluorophenyl)-21-[18F]fluoro-20-oxo-11β,17α-dihydroxy-pregn-4-eno[3,2-c]pyrazole as potential glucocorticoid receptor ligand for positron emission tomography (PET)

Wüst, F.; Knieß, T.; Kretzschmar, M.; Bergmann, R.

  • Bioorganic & Medicinal Chemistry Letters 15(2005), 1303-1306

Synthesis and biological evaluation of S-[11C]methylated mercaptoimidazolde piperazinyl derivatives as potential radioligands for imaging 5-HT1A receptors by positron emission tomography (PET)

Garcia, R.; Xavier, C.; Paulo, A.; Santos, I.; Knieß, T.; Bergmann, R.; Wüst, F.

  • Journal of Labelled Compounds and Radiopharmaceuticals 48(2005), 301-315

N-Arylation of indoles with 4-[18F]fluoroiodobenzene: synthesis of 18F-labelled σ2 receptor ligands for positron emission tomography (PET)

Wüst, F.; Knieß, T.


2004

Fluorine-18 radiolabeling of low-density lipoproteins: a potential approach for characterization and differentiation of metabolism of native and oxidized low-density lipoproteins in vivo.

Pietzsch, J.; Bergmann, R.; Rode, K.; Hultsch, C.; Pawelke, B.; Wüst, F.; van den Hoff, J.

  • Nuclear Medicine and Biology 31(2004), 1043-1050

3-O-Methyl-6-18F-Fluoro-L-Dopa, a New Tumor Imaging Agent: Investigation of Transport Mechanism In Vitro

Bergmann, R.; Pietzsch, J.; Füchtner, F.; Pawelke, B.; Beuthien-Baumann, B.; Johannsen, B.; Kotzerke, J.

  • Journal of Nuclear Medicine 45(2004), 2116-2122

Synthesis and biological evaluation of silylated mixed-ligand 99mTc complexes with the [PNS/S] donor atom set

Fernandes, C.; Knieß, T.; Gano, L.; Seifert, S.; Spies, H.; Santos, I.


Cyclopentadienyl tricarbonyl complexes of 99mTC for the in vivo imaging of the serotonin 5-HT1A receptor in the brain

Saidi, M.; Kretzschmar, M.; Seifert, S.; Bergmann, R.; Pietzsch, H.-J.


Synthesis of 4-([18F]fluoromethyl)-2-chlorophenylisothiocyanate: A novel bifunctional 18F-labelling agent

Wüst, F.; Müller, M.; Bergmann, R.

  • Radiochimica Acta 92(2004)4-6, 349-353

No-carrier added synthesis of 18F-labelled nucleosides using Stille cross-coupling reactions with 4-[18F]fluoroiodobenzene

Wüst, F.; Knieß, T.


The effect of garlic on arteriosclerotic nanoplaque formation and size

Siegel, G.; Malmsten, M.; Pietzsch, J.; Schmidt, A.; Buddecke, E.; Michel, F.; Ploch, M.; Schneider, W.

  • Phytomedicine 11(2004), 24-35

Novel Procedures for Preparing 99mTc(III) Complexes with Tetradentate/Monodentate Coordination of Varying Lipophilicity and Adaptation to 188Re Analogues

Seifert, S.; Künstler, J.-U.; Pietzsch, H.-J.; Pawelke, B.; Bergmann, R.; Spies, H.


Oxidativ modifizierte Lipoproteine und deren Antikörper bei Patienten mit Antiphospholipid-Syndrom

Roch, B.; Kopprasch, S.; Pietzsch, J.; Schröder, H.


The pivotal role of scavenger receptor CD36 and phagocyte-derived oxidants in oxidized low density lipoprotein-induced adhesion to endothelial cells

Kopprasch, S.; Pietzsch, J.; Westendorf, T.; Kruse, H.-J.; Graessler, J.

  • International Journal of Biochemistry and Cell Biology 36(2004)3, 460-471

The protective effects of HDL and its constituents against neutrophil respiratory bust activation by hypochlirite-oxidized LDL

Kopprasch, S.; Pietzsch, J.; Graessler, J.

  • Molecular and Cellular Biochemistry 258(2004), 121-127

Analysis of non-protein amino acids as specific markers of low density lipoprotein apolipoprotein B-100 oxidation in human atherosclerotic lesions: the use of N(O,S)-ethoxycarbonyl trifluoroethyl ester derivatives and GC-MS

Pietzsch, J.; Bergmann, R.; Kopprasch, S.

  • Spectroscopy 18(2004),177-183

Analysis of 6-hydroxy-2-aminocaproic acid (HACA) as a specific marker of protein oxidation: The use of N(O,S)-ethoxycarbonyl trifluoroethyl ester derivatives and gas chromatography/mass spectrometry

Pietzsch, J.; Bergmann, R.

  • Amino Acids 26(2004), 45-51

2003

3-O-Methyl-6-[18F]Fluoro-L-DOPA and its Evaluation in Brain Tumour Imaging

Beuthien-Baumann, B.; Bredow, J.; Burchert, W.; Füchtner, F.; Bergmann, R.; Alheit, H.-D.; Reiss, G.; Hliscs, R.; Steinmeier, R.; Franke, W.-G.; Johannsen, B.; Kotzerke, J.

  • European Journal of Nuclear Medicine and Molecular Imaging (2003) 30: 1004-1008

In vivo Measurement of the Serotonin Transporter with (S)-([18F]fluoromenthyl)-(+)-McN5652

Brust, P.; Hinz, R.; Kuwabara, H.; Hesse, S.; Zessin, J.; Pawelke, B.; Stephan, H.; Bergmann, R.; Steinbach, J.; Sabri, O.

  • Neuropsychopharmacology (2003) 28, 2010-2019

Validation of different chemilumigenic substrates for detecting extracellular generation of reactive oxygen species by phagocytes and endothelial cells

Kopprasch, S.; Pietzsch, J.; Graessler, J.

  • Luminescence (2003) 18: 268-273

Fortschritte in der Aminosäureanalytik: N(O,S)-Ethoxycarbonyl-(trifluoro)ethylester-Derivate

Pietzsch, J.

  • Bioforum 10/2003, 643-645

Measurement of 5-hydroxy-2-aminovaleric acid as a specific marker of iron-mediated oxidation of proline and arginine residues of low density lipoprotein aplipoprotein B-100 in human atherosclerotic lesions

Pietzsch, J.; Bergmann, R.

  • J Clin Pathol (2003) 56: 622-623

Flavonoide: Wirkmechanismen und neue Anwendungsmöglichkeiten (Teil 2)

Pietzsch, J.; Bergmann, R.; Wüst, F.

  • Bioforum (2003) 6:384-385

Flavonoide: Wirkmechanismen und neue Anwendungsmöglichkeiten (Teil 1)

Pietzsch, J.; Bergmann, R.; Wüst, F.

  • Bioforum (2003) 5: 289-291

Synthesis and Enzymatic Evaluation of Nucleosides Derived from 5-Iodo-2'-deoxyuridines

Knieß, T.; Grote, M.; Noll, B.; Johannsen, B.

  • Z. Naturforsch. 58b, 226-230 (2003)

Silylated mixed-ligand rhenium complexes with the [PNS/S] donor atom set

Knieß, T.; Fernandes, C.; Santos, I.; Kraus, W.; Spies, H.

  • Inorganica Chimica Acta 348 (2003) 237-241

Radiolabelling of isopeptide NEpsilon-(Gamma-glutamyl)-L-lysine by conjugation with N-succinimidyl-4-[18F]fluorobenzoate

Wüst, F.; Hultsch, C.; Bergmann, R.; Johannsen, B.; Henle, T.

  • Applied Radiation and Isotopes 59 (2003) 43-48

Increased cholesteryl ester transfer protein (CETP) activity in impaired glucose tolerance: relationship to high density lipoprotein metabolism

Pietzsch, J.; Fücker, K.

  • Croatian Medical Journal 44 (2): 171-177, 2003

Lack of association between serum paraoxonase (PON1) activities and increased oxidized LDL levels in impaired glucose tolerance and newly diagnosed diabetes mellitus

Kopprasch, S.; Pietzsch, J.; Kuhlisch, E.; Gräßler, J.

  • Journal of Clinical Endocrinology & Metabolism 2003; 88: 1711-1716

Analysis of 3-chlorotyrosine as a specific marker of protein oxidation: The use of N(O,S)-ethoxycarbonyl trifluoroethyl ester derivatives and gas chromatography/mass spectrometry

Pietzsch, J.; Kopprasch, S.; Bergmann, R.

  • Rapid Commun. Mass Spectrom 17 (2003):767-770

Autoradiographic imaging of the serotonin ransporter in the brain of rats and pigs using S-([18F]Fluoromethyl)-(+)-McN5652

Kretzschmar, M.; Brust, P.; Zessin, J.; Cumming, P.; Bergmann, R.; Johannsen, B.

  • European Neuropsychopharmacology 13 (2003) 387-397

Synthesis of 4-[18F]fluoroiodobenzene and its application in Sonogashira cross-coupling reactions

Wüst, F.; Knieß, T.

  • Journal of Labelled Compounds and Radiopharmaceuticals 2003, 46: 699-713
  • Lecture (Conference)
    15th International Symposium on Radiopharmaceutical Chemistry; Sydney, 07.-18.08.2003.

2002

Intraindividual comparison of two extracorporeal LDL apheresis methods: lipidfiltration and HELP

Julius, U.; Metzler, W.; Pietzsch, J.; Fassbender, T.; Klingel, R.

  • Int J Artif Organs 25 (2002): 1180-1188

Homocystein: Von der Spezialanalyse zum Routineparameter

Pietzsch, J.

  • Bioforum 9 (2002) 577-580

Synthesis and biological activity of ‚3+1' mixed ligand (3-thiapentane-1,5-dithiolato)oxorhenium(V) complexes bearing 1,2,3,4-tetrahydro(iso)quinoline and quinoline

Zablotskaya, A.; Segal, I.; Germane, S.; Shestakova, I.; Lukevics, E.; Knieß, T.; Spies, H.

  • Applied Organometallic Chemistry 16 (2002) 550-555

In vivo evidence for increased oxidation of circulating LDL in impaired glucose tolerance

Kopprasch, S.; Pietzsch, J.; Kuhlisch, E.; Fuecker, K.; Temelkova-Kurktschiev, T.; Hanefeld, M.; Kühne, H.; Julius, U.; Graessler, J.

  • Diabetes 51 (2002) 3102-3106

Synthesis of hydroxyl silylated rhenium and (99mTc)technetium ‚3+1'mixed ligand complexes

Knieß, T.; Spies, H.; Santos, I.; Zablotskaya, A.

  • J Label Compd Radiopharm 45 (2002) 629-636

Identification of tumor tissue by FTIR spectroscopy in combination with positron emission tomography

Richter, T.; Steiner, G.; Abu-Id, M. H.; Salzer, R.; Bergmann, R.; Rodig, H.; Johannsen, B.

  • Vibrational Spectroscopy 28 (2002) 103-110

Effect of hypoxia/hypercapnia on metabolism of 6-[18F]fluoro-L-DOPA in newborn piglets

Bauer, R.; Brust, P.; Walter, B.; Vorwieger, G.; Bergmann, R.; Elhalag, E.; Fritz, A.; Steinbach, J.; Füchtner, F.; Hinz, R.; Zwiener, U.; Johannsen, B.

  • Brain Research 934 (2002) 22-33

Impaired glucose tolerance is not associated with lipid intolerance

Henkel, E.; Temelkova-Kurtschiev, T.; Köhler, C.; Pietzsch, J.; Leonhardt, W.; Hanefeld, M.

  • Diab Nutr Metab 15 (2002) 84-90

Distribution of estrone sulfatase in rat brain determined by in vitro autoradiography with 16alpha-[18F]fluoroestradiol-3,17beta-disulfamate

Rodig, H.; Brust, P.; Römer, J.; Kasch, H.; Bergmann, R.; Füchtner, F.; Steinbach, J.; Johannsen, B.

  • Applied Radiation and Isotopes 56 (2002) 773-780

Distribution of 16alpha-[18F]fluoro-estradiol-3,17beta-disulfamate (FESDS) in rats, tumour-bearing mice and piglets

Brust, P.; Rodig, H.; Römer, J.; Kasch, H.; Bergmann, R.; Füchtner, F.; Zips, D.; Baumann, M.; Steinbach, J.; Johannsen, B.

  • Applied Radiation and Isotopes 57 (2002) 687-695

Biodistribution and catabolism of 18F-labeled neurotensin(8-13) analogs

Bergmann, R.; Scheunemann, M.; Heichert, C.; Mäding, P.; Wittrisch, H.; Kretzschmar, M.; Rodig, H.; Tourwé, D.; Iterbeke, K.; Chavatte, K.; Zips, D.; Reubi, J. C.; Johannsen, B.

  • Nuclear Medicine and Biology 29 (2002) 61-72

2001

Synthesis and physico-chemical characterization of triorganylsiloxyalkyl monodentate ligands with free mercapto group.

Zablotskaya, A.; Segal, I.; Lukevics, E.; Knieß, T.; Spies, H.

  • Latv. Kim. Z. N4 (2001) 339-342

Radio fluorination and positron emission tomography (PET) as a new approach to study the in vivo distribution and elimination of the advanced glycation endproducts Nepsilon-carboxymethyllysine (CML) and Nepsilon-carboxyethyllysine (CEL)

Bergmann, R.; Helling, R.; Heichert, C.; Scheunemann, M.; Mäding, P.; Wittrisch, H.; Johannsen, B.; Henle, T.

  • Nahrung/Food 45 (2001) 182-188

Intrauterine growth restriction induces up-regulation of cerebral aromatic amino acid decarboxylase activity in newborn piglets: [18F]fluorodopa positron-emission-tomographic study

Bauer, R.; Walter, B.; Vorwieger, G.; Bergmann, R.; Füchtner, F.; Brust, P.

  • Pediatric Research 49 (2001) 474-480

2000

Assessment of the in vitro and in vivo properties of a 99mTc-labeled inhibitor of the multidrug resistant gene product P-glycoprotein.

Bergmann, R.; Brust, P.; Scheunemann, M.; Pietzsch, H.-J.; Seifert, S.; Roux, F.; Johannsen, B.

  • Nucl. Med. Biol. 27 (2000) 135-141

Relation between brain tissue pO2 and dopamine synthesis of basal ganglia - A 18FDOPA-PET study in newborn piglets

Bauer, R.; Brust, P.; Walter, B.; Vorwieger, G.; Bergmann, R.; Füchtner, F.; Steinbach, J.; El-Hallag, E.; Fritz, A.; Johannsen, B.; Zwiener, U.

  • J. Perinat. Med. 28 (2000) 54-60

Functional expression of the serotonin transporter in immortalized rat brain microvessel endothelial cells

Brust, P.; Friedrich, A.; Krizbai, I. A.; Bergmann, R.; Roux, F.; Ganapathy, V.; Johannsen, B.


1999

Nicotinamide-substituted complexes as redox markers. 2. Synthesis of a 99Tc-dihydropyridine mixed-ligand complex and investigation of the stability in tissue homogenates

Rother, A.; Kniess, T.; Pütz, M.; Jungclas, H.; Spies, H.; Johannsen, B.

  • Journal of Labelled Compounds and Radiopharmaceuticals 42, 673-681(1999)

Effective coupling of Re/Tc-MAG3 complexes with amines and nucleobases in aprotic solvents.

Kniess, T.; Noll, S.; Noll, B.; Spies, H.; Johannsen, B.


Upregulation of the Aromatic Amino Acid Decarboxylase under Neonatal Asphyxia

Brust, P.; Bauer, R.; Vorieger, G.; Walter, B.; Bergmann, R.; Füchtner, F.; Steinbach, J.; Zwiener, U.; Johannsen, B.


Regional distribution of cerebral blood volume and cerebral blood flow in newborn piglets - effect of hypoxia / hypercapnia

Bauer, R.; Bergmann, R.; Walter, B.; Brust, P.; Zwiener, U.; Johannsen, B.


Nicotinamide-substituted complexes as redox markers 2. Synthesis of a 99Tc dihydropyridine mixed-ligand complex and investigation of the stability in tissue homogenates

Rother, A.; Knieß, T.; Pütz, M.; Jungclas, H.; Spies, H.; Johannsen, B.

  • J. Labelled Cpd. Radiopharm. 42 (1999) 673-681

1998

Mrp1 Multidrug Resistance-Associated Protein and P-Glykoprotein Expression in Rat Brain Microvessel Endothelial Cells

Regina, A.; Koman, A.; Piciotti, M.; El Hafny, B.; Center, M. S.; Bergmann, R.; Couraud, P.-O.; Roux, F.


Differentiation Between Specific and Nonspecific Effects Related to P-Glycoprotein Inhibition in Immortalized Rat Brain Endothelial Cells

Bergmann, R.; Brust, P.; Johannsen, B.

  • International Journal of Clinical Pharmacology and Therapeutics, Vol. 36, No. 1, 1998 (46-49)

Nicotinamide-Substituted Complexes as Redox Marker

Knieß, T.; Spies, H.; Brandau, W.; Johannsen, B.


Simultaneous Measurement of 18F-FDOPA Metabolism and Cerebral Blood Flow in Newborn Piglets

Brust, P.; Bauer, R.; Walter, B.; Bergmann, R.; Füchtner, F.; Vorwieger, G.; Steinbach, J.; Johannsen, B.; Zwiener, U.


1997

Uptake of 169Yb complexes in normal and tumour cells: influence of ligand and metabolic cell activity and stabilityx of cellular association

Kampf, G.; Knop, G.; Franke, W.-G.; Bergmann, R.; Johannsen, B.

  • Nucl. Med. Biol. 24 (1997) 349-355

1996

High-affinity binding of [3H]paroxetine to caudate nucleus and microvessels from porcine brain

Brust, P.; Bergmann, R.; Johannsen, B.


Rhenium(V) gluconate, a suitable precursor for the preparation of rhenium(V) complexes

Noll, B.; Knieß, T.; Friebe, M.; Spies, H.; Johannsen, B.


1995

Specific binding of (3H)imipramine indicates the presence of a specific serotonin transport system on endothelial cells of porcine brain

Brust, P.; Bergmann, R.; Johannsen, B.


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