Publications Repository - Helmholtz-Zentrum Dresden-Rossendorf

2 Publications

Synthesis, characterization and evaluation of novel chelating agents for copper radionuclides

Stephan, H.; Juran, S.; Walther, M.; Steinbach, J.; Born, K.; Comba, P.

Three different hexadentate bispidine ligands L4 – L6 have been prepared. Studies which have been performed to label these ligands with 67Cu indicate a rapid formation of stable complexes under mild conditions (room temperature, aqueous solution). Challenge experiments of these complexes in the presence of a high excess of competing ligands such as glutathione, histidine and cyclam gave no evidence of radiocopper exchange. The 67Cu complexes of the bispidine ligands investigated are also stable in rat plasma at least for 24 h.

  • Poster
    7th International Symposium on Technetium in Chemistry and Nuclear Medicine, 06.-09.09.2006, Bressanone, Italy
  • Contribution to external collection
    U. Mazzi: Technetium, Rhenium and Other Metals in Chemistry and Nuclear Medicine, Padova: SGEditoriali, 2006, 88-89884-04-5, 219-222

Permalink: https://www.hzdr.de/publications/Publ-8636
Publ.-Id: 8636