Foto: Research Program Cancer Research ©Copyright: Mario BengsImaging and Radiooncology

Health > Cancer Research - All Topics

Foto: Pharmaceutical production in the clean room ©Copyright: HZDR/Rainer WeisflogIn Germany, 500,000 people are diagnosed with cancer every year. New, faster, and primarily more gentle diagnostic and therapeutic procedures can help to fight the disease and to save lifes.

Cancer research at the HZDR addresses the following topics: The scientists conduct research, for example, on new radiopharmaceuticals for the diagnosis of cancer and for the characterization of cancer tissue and, as a further development, also investigate substances for the cancer therapy of tomorrow. Our research has already resulted in the development of new substances. Two radiopharmaceuticals are officially approved and registered pursuant to the pharmaceutical law. These substances, which are produced at the HZDR and subsequently distributed on the market, are needed for the detection of tumors and metastases with a PET camera (PET = Positron Emission Tomography). That is also possible in Dresden – patients can be examined utilizing a full-body scan PET/MRI system which is the first of its kind to have been approved for patients in Germany. HZDR scientists are further developing and improving these innovative imaging procedures which are used in oncology.

They are also investigating particle acceleration with the help of innovative laser technologies. The objective: Making proton-therapy centers smaller while, at the same time, lowering the costs through more powerful lasers and with pulsed magnetic fields. Researchers are also aiming on monitoring irradiation of patients with proton beams in real time.

The HZDR is part of the Competence Network for Radiation Research (KVSF, promoted by the BMBF). This alliance promotes the sustainability of competences in the field of radiation research, in particular, by fostering young scientists.

Important partners are the TU Dresden (Dresden University of Technology) and the University Hospital Carl Gustav Carus Dresden. We jointly operate the OncoRay Center. More information on collaborations with Dresden and Heidelberg partners


Objectives

  • Development and application of new technologies for the diagnosis and therapy of cancer
  • Establishment of laser-accelerated ions in radiation oncology
  • Monitoring and controlling tumor radiation in real time
  • Continued development of individualized and tolerable therapy forms

Press Releases


Involved HZDR institutes


Collaborations


Contacts


Publications

  • Padrela, B.; Mahroo, A.; Tee, M. et al.
    Developing blood-brain barrier arterial spin labelling as a non-invasive early biomarker of Alzheimer’s disease (DEBBIE-AD): a prospective observational multicohort study protocol
    BMJ Open 14(2024)3, e081635 (10.1136/bmjopen-2023-081635)
  • Paschoal, A. M.; Woods, J. G.; Pinto, J. et al.
    Reproducibility of Arterial Spin Labeling Cerebral Blood Flow image processing: A Report of The ISMRM Open Science Initiative for Perfusion Imaging and the ASL MRI Challenge
    Magnetic Resonance in Medicine (2024) (10.1002/mrm.30081)
  • Cegla, P.; Hofheinz, F.; Czepczyński, R. et al.
    Value of [18F] FDG PET/CT parameters of the primary tumor in assessing overall survival in NSCLC patients with cN1-cN3 lymph nodes involvement
    Reports of Practical Oncology and Radiotherapy (2024) (10.5603/rpor.99360)
  • Bigos, K.; Quiles, C.; Lunj, S. et al.
    Tumour response to hypoxia: understanding the hypoxic tumour microenvironment to improve treatment outcome in solid tumours
    Frontiers in Oncology 14(2024), 1331355
  • Peng, X.; Janićijević, Ž.; Lemm, S. et al.
    Impact of Viscosity on Human Hepatoma Spheroids in Soft Core-Shell Microcapsules
    Advanced Healthcare Materials (2024), 2302609 (10.1002/adhm.202302609)
  • Zhang, Y.; Trnkova, P.; Toshito, T. et al.
    A survey of practice patterns for real-time intrafractional motion-management in particle therapy
    Physics and Imaging in Radiation Oncology 26(2023), 100439 (10.1016/j.phro.2023.100439)
  • Trnkova, P.; Zhang, Y.; Toshito, T. et al.
    A survey of practice patterns for adaptive particle therapy for interfractional changes
    Physics and Imaging in Radiation Oncology 26(2023), 100442 (10.1016/j.phro.2023.100442)
  • Tawk, B.; Rein, K.; Schwager, C. et al.
    DNA-Methylome–Based Tumor Hypoxia Classifier Identifies HPV-Negative Head and Neck Cancer Patients at Risk for Locoregional Recurrence after Primary Radiochemotherapy
    Clinical Cancer Research 29(2023)16, 3051-3064 (10.1158/1078-0432.CCR-22-3790)
  • Peters, N.; Trier Taasti, V.; Ackermann, B. et al.
    Consensus guide on CT-based prediction of stopping-power ratio using a Hounsfield look-up table for proton therapy
    Radiotherapy and Oncology 184(2023), 109675 (10.1016/j.radonc.2023.109675)
  • Vrou Offersen, B.; Aznar, M. C.; Bacchus, C. et al.
    The role of ESTRO guidelines in achieving consistency and quality in clinical radiation oncology practice
    Radiotherapy and Oncology 179(2023), 109446 (10.1016/j.radonc.2022.109446)
  • Leichtle, F.; Betzler, A. C.; Eizenberger, C. et al.
    Influence of Bruton’s Tyrosine Kinase (BTK) on Epithelial–Mesenchymal Transition (EMT) Processes and Cancer Stem Cell (CSC) Enrichment in Head and Neck Squamous Cell Carcinoma (HNSCC)
    International Journal of Molecular Sciences 24(2023)17, 13133 (10.3390/ijms241713133)
  • Koi, L.; Bitto, V.; Weise, C. et al.
    Prognostic biomarkers for the response to the radiosensitizer nimorazole combined with RCTx: a pre-clinical trial in HNSCC xenografts
    Journal of Translational Medicine 21(2023), 576 (10.1186/s12967-023-04439-2)
  • Klusa, D.; Lohaus, F.; Franken, A. et al.
    Dynamics of CXCR4 positive circulating tumor cells in prostate cancer patients during radiotherapy
    International Journal of Cancer 152(2023), 2639-2654 (10.1002/ijc.34457)
  • Gantz, S.; Karsch, L.; Pawelke, J. et al.
    Direct visualization of proton beam irradiation effects in liquids by MRI
    Proceedings of the National Academy of Sciences of the United States of America 120(2023)23, e2301160120 (10.1073/pnas.2301160120)
  • Franke, F.; Michlikova, S.; Aland, S. et al.
    Efficient Radial-Shell Model for 3D Tumor Spheroid Dynamics with Radiotherapy
    Cancers 15(2023), 5645 (10.3390/cancers15235645)
  • Corti, C.; Cobanaj, M.; Dee, E. C. et al.
    Artificial intelligence in cancer research and precision medicine: Applications, limitations and priorities to drive transformation in the delivery of equitable and unbiased care
    Cancer Treatment Reviews 112(2023), 102498 (10.1016/j.ctrv.2022.102498)
  • Baumann, M.; Bacchus, C.; Aznar, M. C. et al.
    Are hybrid conferences the new standard?
    Radiotherapy and Oncology 128(2023), 109695 (10.1016/j.radonc.2023.109695)
  • Runge, R.; Reissig, F.; Herzog, N. et al.
    Combining Cisplatin with Different Radiation Qualities—Interpretation of Cytotoxic Effects In Vitro by Isobolographic Analysis
    Pharmaceuticals 16(2023)12, 1720 (10.3390/ph16121720)
  • Towers, R.; Trombello, L.; Fusenig, M. et al.
    Bone marrow-derived mesenchymal stromal cells obstruct AML-targeting CD8+ clonal effector and CAR T cell function while promoting a senescence-associated phenotype
    Cancer Immunology, Immunotherapy 73(2024), 8 (10.1007/s00262-023-03594-1)
  • Miederer, M.; Benešová-Schäfer, M.; Mamat, C. et al.
    Alpha-emitting Radionuclides: Current Status and Future Perspectives
    Pharmaceuticals 17(2024), 76 (10.3390/ph17010076)
  • Janićijević, Ž.; Huang, T.; Sandoval Bojorquez, D. I. et al.
    Design and Development of Transient Sensing Devices for Healthcare Applications
    Advanced Science (2024) (10.1002/advs.202307232)
  • Ludwig, F.-A.; Laurini, E.; Schmidt, J. et al.
    [¹⁸F]Fluspidine – a PET tracer for imaging of σ1 receptors in the central nervous system
    Pharmaceuticals 17(2024)166, 1-21 (10.3390/ph17020166)
  • Weiß, A.; Löck, S.; Xu, T. et al.
    Prediction of radiation pneumonitis using the effective α/β of lungs and heart in NSCLC patients treated with proton beam therapy
    Radiotherapy and Oncology 190(2024), 110013 (10.1016/j.radonc.2023.110013)
  • Samuels, M.; Falkenius, J.; Bar-Ad, V. et al.
    A Phase I Study of the DNA-PK Inhibitor Peposertib in Combination with Radiotherapy with or without Cisplatin in Patients with Advanced Head and Neck Tumors
    International Journal of Radiation Oncology Biology Physics 118(2024)3, 743-756 (10.1016/j.ijrobp.2023.09.024)
  • Mazzola, G. C.; Bergamaschi, L.; Vincini, M. et al.
    Patients’ needs in Proton Therapy: a survey among 10 European Facilities
    Clinical and Translational Radiation Oncology 43(2023), 100670 (10.1016/j.ctro.2023.100670)
  • Lococo, F.; Boldrini, L.; Diepriye, C.-D. et al.
    Lung cancer multi-omics digital human avatars for integrating precision medicine into clinical practice: the LANTERN study
    BMC Cancer 23(2023), 540 (10.1186/s12885-023-10997-x)
  • Elkhamisy, S. A.; Valentini, C.; Lattermann, A. et al.
    Normo-or hypo-fractionated photon or proton radiotherapy in the management of locally advanced unresectable pancreatic cancer: a systematic review
    Cancers 15(2023), 3771 (10.3390/cancers15153771)
  • Kreller, M.; Walther, M.; Brühlmann, S. A. et al.
    Production of medical radionuclides in the Center for Radiopharmaceutical Tumor Research – a status report
    Instruments 8(2024)1, 10 (10.3390/instruments8010010)
  • Zhao, X.; Kolbinger, F. R.; Distler, M. et al.
    Portable Droplet-Based Real-Time Monitoring of Pancreatic α-Amylase in Postoperative Patients
    Biosensors and Bioelectronics 251(2024), 116034 (10.1016/j.bios.2024.116034)
  • Szöllősi, D.; Hajdrik, P.; Tordai, H. et al.
    Molecular imaging of bacterial outer membrane vesicles based on bacterial surface display
    Scientific Reports 13(2023), 18752 (10.1038/s41598-023-45628-9)
  • Gorodetska, I.; Offerman, A.; Püschel, J. et al.
    ALDH1A1 drives prostate cancer metastases and radioresistance by interplay with AR- and RAR-dependent transcription
    Theranostics 14(2024)2, 714-737 (10.7150/thno.88057)
  • Drewitz, L.; Kegler, A.; Arndt, C. et al.
    Development Of A Novel ACE2 Decoy For Both SARS-CoV-2 Variant Neutralization And Infected Cell Elimination Via Unmodified Or CAR Modified Immune Cells
    Human Gene Therapy 34(2023), 92 (10.1089/hum.2023.29252.abstracts)
  • Brühlmann, S. A.; Walther, M.; Kopka, K. et al.
    Production of the PET radionuclide 61Cu via the 62Ni(p,2n)61Cu Nuclear Reaction
    EJNMMI Radiopharmacy and Chemistry 9(2024)1, 3 (10.1186/s41181-023-00233-z)
  • Misko, V. R.; Baraban, L.; Makarov, D. et al.
    Selecting active matter according to motility in an acoustofluidic setup: Self-propelled particles and sperm cells
    Soft Matter 19(2023), 8635 (10.1039/D3SM01214J)
  • Horst, F. E.
    Calorimetry as a tool to improve the dosimetric accuracy in novel radiotherapy modalities
    Physics and Imaging in Radiation Oncology 28(2023), 100516 (10.1016/j.phro.2023.100516)
  • Janićijević, Ž.; Nguyen Le, T. A.; Baraban, L.
    Extended-gate field-effect transistor chemo- and biosensors: State of the art and perspectives
    Next Nanotechnology 3–4(2023), 100025 (10.1016/j.nxnano.2023.100025)
  • Wodtke, R.; Laube, M.; Hauser, S. et al.
    Preclinical evaluation of an ¹⁸F-labeled Nε-acryloyllysine piperazide for covalent targeting of transglutaminase 2
    EJNMMI Radiopharmacy and Chemistry 9(2024)1, 1 (10.1186/s41181‑023‑00231‑1)
  • Craig, A.; Kogler, J.; Laube, M. et al.
    Preparation of 18F-Labeled Tracers Targeting Fibroblast Activation Protein via Sulfur [18F]Fluoride Exchange Reaction
    Pharmaceutics 15(2023)12, 2749 (10.3390/pharmaceutics15122749)
  • Patt, M.; Decristoforo, C.; de Martini, A. et al.
    The revision of the pharmaceutical legislation – it is time to act for nuclear medicine in Europe
    European Journal of Nuclear Medicine and Molecular Imaging 51(2023), 20-24 (10.1007/s00259-023-06472-1)
  • Broghammer, F.; Gouda, M.; Korovina, I. et al.
    Resistance of HNSCC cell models to pan-FGFR inhibition depends on the EMT phenotype associating with clinical outcome
    Molecular Cancer 23(2024), 39 (10.1186/s12943-024-01954-8)
  • González Soto, K. E.; Rodrigues Loureiro, L. R.; Bartsch, T. et al.
    Targeting colorectal cancer cells using AND-gated Adaptor RevCAR T-cells
    Frontiers in Immunology 14(2023), 1302354 (10.3389/fimmu.2023.1302354)
  • Krutzek, F.; Donat, C.; Stadlbauer, S.
    Chelator Impact: Investigating the Pharmacokinetic Behavior of Copper-64 Labeled PD-L1 Radioligands
    EJNMMI Radiopharmacy and Chemistry 9(2024), 14 (10.1186/s41181-024-00243-5)
  • Janićijević, Ž.; Nguyen Le, T. A.; Alsadig, A. et al.
    Methods gold standard in clinic millifluidics multiplexed extended gate field-effect transistor biosensor with gold nanoantennae as signal amplifiers
    Biosensors and Bioelectronics 241(2023), 115701 (10.1016/j.bios.2023.115701)
  • Rodrigues Loureiro, L. R.; Hoffmann, L.; Neuber, C. et al.
    Immunotheranostic target modules for imaging and navigation of UniCAR T-cells to strike FAP-expressing cells and the tumor microenvironment
    Journal of Experimental & Clinical Cancer Research 42(2023), 341 (10.1186/s13046-023-02912-w)
  • Zhao, X.; Ruelens, P.; Farr, A. D. et al.
    Bacterial filamentation mediates cross-protection against β-lactam antibiotics in droplet microreactors
    Frontiers in Microbiology 14(2023), 1294790 (10.3389/fmicb.2023.1294790)
  • Zschaeck, S.; Klinger, B.; van den Hoff, J. et al.
    Combination of tumor asphericity and an extracellular matrix-related prognostic gene signature in non-small cell lung cancer patients
    Scientific Reports 13(2023), 20840 (10.1038/s41598-023-46405-4)
  • Korde, A.; Patt, M.; Selivanova, S. et al.
    Position Paper to facilitate patient access to radiopharmaceuticals - considerations for a suitable pharmaceutical regulatory framework
    EJNMMI Radiopharmacy and Chemistry 9(2024)1, 2 (10.1186/s41181-023-00230-2)
  • Klotz, D. M.; Schwarz, F.; Dubrovska, A. et al.
    Establishment and Molecular Characterization of an In Vitro Model for PARPi-Resistant Ovarian Cancer.
    Cancers 15(2023)15, 3774 (10.3390/cancers15153774)
  • Kubeil, M.; Suzuki, Y.; Casulli, M. A. et al.
    Exploring the Potential of Nanogels: From Drug Carriers to Radiopharmaceutical Agents
    Advanced Healthcare Materials 13(2023)1, 2301404 (10.1002/adhm.202301404)
  • Poldrack, R. A.; Markiewicz, C. J.; Appelhoff, S. et al.
    The Past, Present, and Future of the Brain Imaging Data Structure (BIDS)
    Imaging Neuroscience 2(2024), 1-19 (10.1162/imag_a_00103)
  • Korovina, I.; Elser, M.; Borodins, O. et al.
    β1 integrin mediates unresponsiveness to PI3Kα inhibition for radiochemosensitization of 3D HNSCC models
    Biomedicine and Pharmacotherapy 171(2024), 116217 (10.1016/j.biopha.2024.116217)
  • Kopp, I.; Cieslik, P.; Anger, K. et al.
    Bispidine Chelators for Radiopharmaceutical Applications with Lanthanide, Actinide and Main Group Metal Ions
    Inorganic Chemistry 62(2023)50, 20754-20768 (10.1021/acs.inorgchem.3c02340)
  • Krutzek, F.; Donat, C.; Stadlbauer, S.
    Exploring Hydrophilic PD-L1 Radiotracers Utilizing Phosphonic Acids: Insights Into Unforeseen Pharmacokinetics
    International Journal of Molecular Sciences 24(2023)20, 15088 (10.3390/ijms242015088)
  • Nenoff, L.; Amstutz, F.; Murr, M. et al.
    Review and recommendations on deformable image registration uncertainties for radiotherapy applications
    Physics in Medicine and Biology 68(2023), 24TR01 (10.1088/1361-6560/ad0d8a)
  • Wang, T.; Wang, J.; Chen, L. et al.
    Development of a Highly Specific 18F-labeled Radioligand for Imaging of Sigma-2 Receptor in Brain Tumor
    Journal of Medicinal Chemistry 66(2023)18, 12840-12857 (10.1021/acs.jmedchem.3c00735)
  • Cegla, P.; Hofheinz, F.; Burchardt, E. et al.
    Asphericity derived from [18F]FDG PET as a new prognostic parameter in cervical cancer patients
    Scientific Reports 13(2023)1, 8423 (10.1038/s41598-023-35191-8)
  • Maria Sag, S. J.; Menhart, K.; Hitzenbichler, F. et al.
    18F-FDG PET/CT-derived total lesion glycolysis predicts abscess formation in patients with surgically confirmed infective endocarditis: Results of a retrospective study at a tertiary center
    Journal of Nuclear Cardiology 30(2023), 2400-2414 (10.1007/s12350-023-03285-5)
  • Starke, S.; Zwanenburg, A.; Leger, K. et al.
    Multitask Learning with Convolutional Neural Networks and Vision Transformers Can Improve Outcome Prediction for Head and Neck Cancer Patients
    Cancers 15(2023)19, 4897 (10.3390/cancers15194897)
  • Elser, M.; Vehlow, A.; Juratli, T. et al.
    Simultaneous inhibition of discoidin domain receptor 1 and integrin αVβ3 radiosensitizes human glioblastoma cells
    American Journal of Cancer Research 13(2023)10, 4597-4612
  • Samimi, R.; Shiri, I.; Ahmadyar, Y. et al.
    Radiomics predictive modeling from dual-time-point FDG PET Ki parametric maps: application to chemotherapy response in lymphoma
    EJNMMI Research 13(2023)1, 70 (10.1186/s13550-023-01022-0)
  • Krutzek, F.; Donat, C.; Ullrich, M. et al.
    Design, Synthesis, and Biological Evaluation of Small Molecule Based Radioligands with Improved Pharmacokinetic Properties for Imaging of Programmed Death Ligand 1
    Journal of Medicinal Chemistry 66(2023)23, 15894-15915 (10.1021/acs.jmedchem.3c01355)
  • Yaromina, A.; Koi, L.; Schuitmaker, L. et al.
    Overcoming radioresistance with the hypoxia-activated prodrug CP-506: A pre-clinical study of local tumour control probability
    Radiotherapy and Oncology 186(2023), 109738 (10.1016/j.radonc.2023.109738)
  • Lai, T. H.; Wenzel, B.; Dukic-Stefanovic, S. et al.
    Radiosynthesis and biological evaluation of [¹⁸F]AG-120 for PET imaging of the mutant isocitrate dehydrogenase 1 in gliomas
    European Journal of Nuclear Medicine and Molecular Imaging (2023) (10.1007/s00259-023-06515-7)
  • Schellhammer, S.; Meric, I.; Löck, S. et al.
    Hybrid treatment verification based on prompt gamma-rays and fast neutrons: Multivariate modelling for proton range determination
    Frontiers in Physics 11(2023), 1295157 (10.3389/fphy.2023.1295157)
  • Xia, P.; Dubrovska, A.
    CD98 heavy chain as a prognostic biomarker and target for cancer treatment
    Frontiers in Oncology 13(2023), 1251100 (10.3389/fonc.2023.1251100)
  • Blei, M. K.; Drobot, B.; Kretzschmar, J. et al.
    Bestimmung von logK-Werten macropa-basierter Chelatoren für die stabile Komplexierung von 131Ba, 223/224Ra und 133La
    Nuklearmedizin 62(2023), 149
  • Reissig, F.; Zarschler, K.; Novy, Z. et al.
    Entwicklung alternativer Verbindungen für die PSMA-Therapie mit Actinium-225
    Nuklearmedizin 62(2023), 147
  • Blei, M. K.; Waurick, L.; Reissig, F. et al.
    Equilibrium Thermodynamics of Macropa Complexes with Selected Metal Isotopes of Radiopharmaceutical Interest
    Inorganic Chemistry 62(2023)50, 20699-20709 (10.1021/acs.inorgchem.3c01983)
  • Löser, R.; Kuchar, M.; Wodtke, R. et al.
    Lysyl oxidases as targets for cancer therapy and diagnostic imaging
    ChemMedChem 18(2023)18, e202300331 (10.1002/cmdc.202300331)
  • Crespo, E.; Rodrigues Loureiro, L. R.; Arndt, C. et al.
    Turning an Immunosuppressive Marker Into a T-Cell Activating Signal: Using the RevCAR System to Target Immune Checkpoints
    Human Gene Therapy 54(2023) (10.1089/hum.2023.29252.abstracts)
  • Jósza, T.; Petr, J.; Payne, S. J. et al.
    MRI-based parameter inference for cerebral perfusion modelling in health and ischaemic stroke
    Computers in Biology and Medicine 166(2023), 107543 (10.1016/j.compbiomed.2023.107543)
  • Richter, S.; Steenblock, C.; Lemm, S. et al.
    Improving susceptibility of neuroendocrine tumors to radionuclide therapies: personalized approaches towards complementary treatments
    Theranostics 14(2024)1, 17-32 (10.7150/thno.87345)
  • Kegler, A.; Drewitz, L.; Arndt, C. et al.
    A novel ACE2 decoy for both neutralization of SARS-CoV-2 variants and killing of infected cells
    Frontiers in Immunology 14(2023), 1204543 (10.3389/fimmu.2023.1204543)
  • Gerlach, S.; Balling, F.; Schmidt, A. K. et al.
    Three-dimensional acoustic monitoring of laser-accelerated protons in the focus of a pulsed-power solenoid lens
    High Power Laser Science and Engineering 11(2023), e38 (10.1017/hpl.2023.16)
  • Braun, S.; Jelača, S.; Laube, M. et al.
    Synthesis and In Vitro Biological Evaluation of p-Carborane-based Di-tert-butylphenol Analogs
    Molecules 28(2023), 4547 (10.3390/molecules28114547)
  • Peschke, J.; Bergmann, R.; Mehnert, M. et al.
    FLT3-directed UniCAR T-cell therapy of Acute Myeloid Leukaemia
    British Journal of Haematology 202(2023)6, 1137-1150 (10.1111/bjh.18971)
  • Krutzek, F.; Donat, C.; Ullrich, M. et al.
    Design and Biological Evaluation of Small-Molecule PET-Tracers for Imaging of Programmed Death Ligand 1
    Cancers 15(2023), 2638 (10.3390/cancers15092638)
  • Ueberham, L.; Gündel, D.; Kellert, M. et al.
    Development of the High-Affinity Carborane-Based Cannabinoid Receptor Type 2 PET Ligand [18F]LUZ5-d8
    Journal of Medicinal Chemistry 66(2023), 5242-5260 (10.1021/acs.jmedchem.3c00195)
  • Wenzel, B.; Schmid, M.; Teodoro, R. et al.
    Radiofluorination of an anionic, azide-functionalized teroligomer by copper-catalyzed azide-alkyne cycloaddition
    Nanomaterials 13(2023)14, 2095 (10.3390/nano13142095)
  • Valentini, C.; Ebert, N.; Koi, L. et al.
    Preclinical trial comparing radiotherapy alone versus standard radiochemotherapy in three human papilloma virus (HPV) negative and three HPV-positive head and neck squamous cell carcinoma (HNSCC) xenograft tumour models.
    Radiotherapy and Oncology 183(2023), 109546 (10.1016/j.radonc.2023.109546)
  • Koevoets, E. W.; Petr, J.; Monninkhof, E. M. et al.
    Effect of physical exercise on brain perfusion in chemotherapy-treated breast cancer patients: a randomized controlled trial (PAM study)
    Journal of Magnetic Resonance Imaging (2024) (10.1002/jmri.28967)
  • Wamelink, I. J. H. G.; Azizova, A.; Booth, T. C. et al.
    Brain tumor imaging without gadolinium-based contrast agents: Feasible or Fantasy?
    Radiology 310(2024)2 (10.1148/radiol.230793)
  • Striese, F.; Neuber, C.; Gräßel, S. et al.
    Preclinical Characterization of the 177Lu-Labeled Prostate Stem Cell Antigen (PSCA)-Specific Monoclonal Antibody 7F5
    International Journal of Molecular Sciences 24(2023)11, 9420 (10.3390/ijms24119420)
  • Pfeifer Serrahima, J.; Zhang, C.; Oberoi, P. et al.
    Multivalent adaptor proteins specifically target NK cells carrying a universal chimeric antigen receptor to ErbB2 (HER2)-expressing cancers
    Cancer Immunology, Immunotherapy 72(2023), 2905-2918 (10.1007/s00262-023-03374-x)
  • Braun, S.; Paskas, S.; Laube, M. et al.
    Carborane-based Tebufelone Analogs and their Biological Evaluation In Vitro
    ChemMedChem 18(2023), e202300206 (10.1002/cmdc.202300206)
  • Horst, F. E.; Beyreuther, E.; Bodenstein, E. et al.
    Passive SOBP generation from a static proton pencil beam using 3D-printed range modulators for FLASH experiments
    Frontiers in Physics 11(2023), 1213779. (10.3389/fphy.2023.1213779)
  • Grehn, M.; Mandija, S.; Miszczyk, M. et al.
    STereotactic Arrhythmia Radioablation (STAR): the Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary consortium (STOPSTORM.eu) and review of current patterns of STAR practice in Europe
    Europace 25(2023)4, 1284-1295 (10.1093/europace/euac238)
  • Michlikova, S.; Rabasco Meneghetti, A.; Löck, S. et al.
    Radiomics-based prediction of radiosensitivity from preclinical HNSCC histopathology images
    Radiotherapy and Oncology 182(2023)S1, S593 (10.1016/S0167-8140(23)08450-5)
  • Abdelfatah Saleh Hassan, H. A.; Mitwasi, N.; Ullrich, M. et al.
    Specific and safe targeting of glioblastoma using switchable and logic-gated RevCAR T cells
    Frontiers in Immunology 14(2023), 1166169 (10.3389/fimmu.2023.1166169)
  • Useini, L.; Komazec, T.; Laube, M. et al.
    Isonimesulide and its carborane analogues as isoform-selective COX inhibitors and antitumor agents
    Advanced Therapeutics 6(2023)8, 2300117 (10.1002/adtp.202300117)
  • Ullrich, M.; Brandt, F.; Löser, R. et al.
    Comparative saturation binding analysis of ⁶⁴Cu-labeled somatostatin analogs using cell homogenates and intact cells
    ACS Omega 8(2023)26, 24003-24009 (10.1021/acsomega.3c02755)
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