Department of Positron Emission TomographyThe Positron Emission Tomography (PET) represents a non-invasive method which allows for quantitative examinations of physiological and biochemical processes. The method is based on radiolabeled, metabolically active molecules acting as molecular probes.
In our department, scientists from diverse fields (physics, medicine, computer science) are dealing with different problems by using this method. The main focus lies on the application of PET for medical research projects with oncological background. For this purpose, several tomographs are available: an ECAT HR+ for patient examinations as well as a microPET P4, a CT and MRT for examinations of small animals (mainly mice and rats). To enable an optimal application of PET, we work on multiple improvements concerning the raw data processing of this method. The investigation of an event-based data acquisition (list mode) as well as the development of motion correction methods represents a focus of our activities. Furthermore, we deal with problems in fields like tomographic image reconstruction, quantitative data analysis (segmentation methods) and mathematical modelling of pharmacokinetic transport processes.