Institute of Radiopharmaceutical Cancer Research
The Institute of Radiopharmaceutical Cancer Research is engaged in Radiopharmaceutical Cancer Research. Chemical, biological and physical working groups work together to increase the knowledge in the scopes of Molecular Imaging and Tumor Therapy.
Our focus is directed to mainly experimental work for characterisation and therapy of tumors. This includes contributions for the understanding of the pathogenesis of cancerogonesis and inflammations. Our basic aim is the development of specific radioactive labelled substances (so-called radiotracers and radionuclide therapeuticals) and their application in Translational Tumor Research as well as for our research purposes. The current research program of the institute is focused on the topics PET and multimodal imaging, radionuclide therapeutics and neuroradiopharmaceuticals.
As part of our institute, the Rossendorf Center for Positron Emission Tomography (PET Center) was established together with the Medical Faculty/University Hospital to carry out special medical research programs and patient investigations with positron emission tomography (PET). Fully integrated into our research activities related to brain research the Research Site Leipzig works on radiopharmceutial research on the diagnoses of neurodegenerative diseases via molecular tracers. In addition, the institute is an important part and partner of the OncoRay - Center for Radiation Research in Oncology and complements its aims for endoradionuclid therapy by supporting it with its competences in preclinical molecular imaging.
Young Researcher Programme
The institute is also engaged in the education and training of the next generation of scientists and technicians. Beside its work in applied basic research the staff of the institute implements its comprehensive expert knowledge and its wealth of experience into the education at the Dresden University of Technology. Students can attend lectures in Radiopharmaceutical Chemistry, Bioinorganic Chemistry and Positron Emission Tomography. Trainees, graduants and Ph.D. students from Germany and foreign universities have the possibility to work at multidisciplinary subjects in modern and well equipped laboratories.
Currently, two Helmholtz funded network projects are conducted at the Institute of Radiopharmaceutical Cancer Research. The Virtual Institute „NanoTracking“ led by Dr. Holger Stephan is directed towards the development of novel functionalized nanomaterials for application in the imaging of cancer aiming at the design of tailor-made nanomaterials and providing a deeper understanding of their interactions in vitro and in vivo.
As part of the portfolio theme “Technology and Medicine” the Institute of Radiopharmaceutical Cancer Research contributes significantly to investigate the characteristics of polymeric biomaterials within the body and to identify potential interactions and degradation products by applying different imaging techniques.