Department of Biophysics
Research
The Biophysics Department conducts interdisciplinary research at the interface of biomolecular function, physical chemistry and radiochemistry. The activities contribute to the Helmholtz Research Programmes Nuclear Safety and Cancer Research in the Helmholtz-Association. We are member of the Cluster of Excellence "Physics of Life"(1) (PoL) in Dresden.
We are particularly interested in:
- structural and dynamic aspects of biomembranes
- conformational transitions in membrane proteins
- interactions between (radio)metals and biomolecules
- effects of metals and radionuclides on the metabolism of microorganisms (Televised MDR report(2))
Education
The Biophysics department participates in the Dresden International Graduate School for Biomedicine and Bioengineering (DIGS-BB)(3) supported by the Excellence Initiative of the German federal and state governments.
Practicals on Molecular Spectroscopy and Calorimetry are offered. The following lectures are held at the technische Universität Dresden and are elgible for the Master Specialization "Soft Condensed Matter and Biological Physics":
- Biological Thermodynamics (English, summer semester)
- Biophysical Methods (German, winter semester)
Seminar lectures for the International BIOTEC-Master Programme,
- Vibrational Spectroscopy (English)
- Absorption and Fluorescence Spectroscopy (English)
Experimental Methods
- Fourier transform infrared spectroscopy
- Circular dichroism
- Static and time-resolved fluorescence spectroscopy
- Calorimetry(4)
- Mass-Spectroscopy
Spectroscopic data are evaluated in combination with Density Functional Theory to understand photochemoical and photophysical properties of organic complexes of actinides
Latest Publication
Fate of Oxidation States at Actinide Centers in Redox-Active Ligand Systems Governed by Energy Levels of 5f Orbitals
Takeyama, T.(5); Tsushima, S.(6); Gericke, R.(7); Kaden, P.(8); März, J.(9); Takao, K.(10)
We report the formation of a Np(IV) complex from the complexation of Np(VI)O22+ with the redox-active ligand tBu-pdiop2-=2,6-bis[N-(3,5-di-tert-butyl-2-hydroxyphenyl)iminomethyl]pyridine. To the best of our knowledge, this is the first example of the direct complexation-induced chemical reduction of Np(VI)O22+ to Np(IV). In contrast, the complexation of U(VI)O22+ with tBu-pdiop2- did not induce the reduction of U(VI)O22+, not even after the two-electron electrochemical reduction of [U(VI)O2(tBu-pdiop)]. This contrast between the Np and U systems may be ascribed to the decrease of the energy of the 5f orbitals in Np compared to those in U. The present findings indicate that the redox chemistry between U(VI)O22+ and Np(VI)O22+ should be clearly differentiated in redox-active ligand systems.
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Chemistry - A European Journal 29(2023)69, e202302702
Online First (2023) DOI: 10.1002/chem.202302702(11)
Team
Head | |||||
Name | Bld./Office | +49 351 260 | |||
---|---|---|---|---|---|
Prof. Dr. Karim Fahmy | 801/P301 | 2952 3601 | k.fahmyhzdr.de | ||
Employees | |||||
Name | Bld./Office | +49 351 260 | |||
Dr. Jana Oertel | 801/P302 | 2978 3570 | j.oertel@hzdr.de(12) | ||
Jenny Philipp | 801/P303 | 3247 3568 | j.philipphzdr.de | ||
Prof. Dr. Satoru Tsushima | 801/P302 | 2978 | s.tsushimahzdr.de | ||
Other employees | |||||
Name | Bld./Office | +49 351 260 | |||
Dr. Charlotte Kielar | 801/P303 | 3247 3892 | c.kielarhzdr.de |
Physical Chemistry of Biomolecular Condensates
Head | |||||
Name | Bld./Office | +49 351 260 | |||
---|---|---|---|---|---|
Dr. Ellen Adams | 801/P301 | 2911 | e.adamshzdr.de | ||
Employees | |||||
Name | Bld./Office | +49 351 260 | |||
Artur Czajkowski | 801/P303 | 3375 | a.czajkowskihzdr.de | ||
Likhitha Chakra Priya Pulibandla | 801/P303 | 3375 | l.pulibandlahzdr.de | ||
Juliane Tippmann | j.tippmannhzdr.de |
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URL of this article
https://www.hzdr.de/db/Cms?pOid=26495