Publications of Institute of Radiopharmaceutical Cancer Research

41 Publications

2019

Introduction of the New Center for Radiopharmaceutical Cancer Research at Helmholtz-Zentrum Dresden-Rossendorf

Kreller, M.; Pietzsch, H.-J.; Walther, M.; Tietze, H.; Kaever, P.; Knieß, T.; Füchtner, F.; Steinbach, J.; Preusche, S.


2015

Convenient recycling and reuse of bombarded [18O]H2O for the production and the application of [18F]F

Rötering, S.; Franke, K.; Zessin, J.; Brust, P.; Füchtner, F.; Fischer, S.; Steinbach, J.


2013

Radionuclide impurities in [F-18]F- and [F-18]FDG for positron emission tomography

Koehler, M.; Degering, D.; Zessin, J.; Fuechtner, F.; Konheiser, J.


2012

Imaging of the brain serotonin transporters (SERT) with 18F-labelled fluoromethyl-McN5652 and PET in humans

Hesse, S.; Brust, P.; Mäding, P.; Becker, G.-A.; Seese, A.; Patt, M.; Sorger, D.; Zessin, J.; Sacher, J.; Lobsien, D.; Habermann, B.; Meyer, P. M.; Füchtner, F.; Luthardt, J.; Bresch, A.; Steinbach, J.; Sabri, O.


2011

Visualization of the focus in congenital hyperinsulinism by intraoperative sonography

von Rohden, L.; Mohnike, K.; Mau, H.; Eberhard, T.; Mohnike, W.; Blankenstein, O.; Empting, S.; Koch, M.; Fuechtner, F.; Barthlen, W.


Intraoperative Sonography: A Technique for Localizing Focal Forms of Congenital Hyperinsulinism in the Pancreas

von Rohden, L.; Mohnike, K.; Mau, H.; Eberhard, T.; Mohnike, W.; Blankenstein, O.; Empting, S.; Koch, M.; Füchtner, F.; Barthlen, W.


2008

Radiation treatment planning in brain tumours Potential impact of 3-O-methyl-6-[18F]fluoro-L-DOPA and PET

Alheit, H.; Oehme, L.; Winkler, C.; Füchtner, F.; Hoepping, A.; Grabowski, J.; Kotzerke, J.; Beuthien-Baumann, B.


Congenital hyperinsulinism: [18F]DOPA PET/CT scan of a focal lesion in the head of the pancreas

Kapoor, R. R.; Gilbert, C.; Mohnike, K.; Blankenstein, O.; Füchtner, F.; Hussain, K.


Factors affecting the specific activity of [18F]fluoride from a [18O]water target

Füchtner, F.; Preusche, S.; Mäding, P.; Zessin, J.; Steinbach, J.


Evaluation of 18F- L-DOPA PET-CT for surgery in focal congenital hyperinsulinism

Barthlen, W.; Mau, H.; Koch, M.; Höhne, C.; Blankenstein, O.; Mohnike, W.; Eberhard, T.; Füchtner, F.; Lorenz-Depiereux, B.; Mohnike, K.

  • Journal of Clinical Endocrinology and Metabolism 93(2008)3, 869-875

18F-DOPA Positron Emission Tomography for Preoperative Localization in Congenital Hyperinsulinism

Mohnike, K.; Blankenstein, O.; Minn, H.; Mohnike, W.; Füchtner, F.; Otonovski, T.


Aspects of 6-[18F]fluoro-L-DOPA preparation: Deuterochloroform as a substitute solvent for Freon 11

Füchtner, F.; Zessin, J.; Mäding, P.; Wüst, F.


2007

L-Type Amino Acid Transporters LAT1 and LAT4 in Cancer: Uptake of 3-O- Methyl-6-18F-Fluoro-L-Dopa (18F-OMFD) in Human Adenocarcinoma and Squamous Cell Carcinoma in vitro and in vivo

Haase, C.; Bergmann, R.; Füchtner, F.; Hoepping, A.; Pietzsch, J.


2006

Synthesis of a 11C-labelled taxane derivative by [1-11C]acetylation

Mäding, P.; Zessin, J.; Pleiß, U.; Füchtner, F.; Wüst, F.


18F-Labelling of a potent nonpeptide CCR1 antagonist: Synthesis of 1-(5-chloro-2-{2-[(2R)-4-(4-[18F]fluorobenzyl)-2methylpiperazin-1-yl]-2-oxoethoxy}phenyl)urea in an automated module

Mäding, P.; Füchtner, F.; Johannsen, B.; Steinbach, J.; Hilger, C. S.; Friebe, M.; Halks-Miller, M.; Horuk, R.; Mohan, R.

  • Journal of Labelled Compounds and Radiopharmaceuticals 49 (2006) 253-262

2005

Effect of Moderate Hypercapnic Hypoxia on Cerebral Dopaminergic Activity and Brain O2 Uptake in Intrauterine Growth–Restricted Newborn Piglets

Bauer, R.; Walter, B.; Vorwieger, G.; Fritz, A.; Füchtner, F.; Zwiener, U.; Brust, P.


Module-assisted synthesis of the bifunctional labelling agent N-succinimidy 4-[18F]fluorobenzoate ([18F]SFB)

Mäding, P.; Füchtner, F.; Wüst, F.

  • Applied Radiation and Isotopes 63(2005), 329-332

2004

The Influx of Neutral Amino Acids into the Porcine Brain During Development: A Positron Emission Tomography Study

Brust, P.; Vorwieger, G.; Walter, B.; Füchtner, F.; Stark, H.; Kuwabara, H.; Steinbach, J.; Bauer, R.

  • Developmental Brain Research 152(2004), 241-253

3-O-Methyl-6-18F-Fluoro-L-Dopa, a New Tumor Imaging Agent: Investigation of Transport Mechanism In Vitro

Bergmann, R.; Pietzsch, J.; Füchtner, F.; Pawelke, B.; Beuthien-Baumann, B.; Johannsen, B.; Kotzerke, J.

  • Journal of Nuclear Medicine 45(2004), 2116-2122

Developmental changes in the activity of aromatic amino acid decarboxylase and catechol-O-methyl transferase in pigs: a positron emission tomography study

Brust, P.; Walter, B.; Hinz, R.; Füchtner, F.; Müller, M.; Steinbach, J.; Bauer, R.

  • Neuroscience Letters, 364(2004)3, 159-163

Age-dependent effects of severe traumatic brain injury on cerebral dopaminergic activity in newborn and juvenile pigs

Walter, B.; Brust, P.; Füchtner, F.; Müller, M.; Hinz, R.; Kuwabara, H.; Fritz, H.; Zwiener, U.; Bauer, R.

  • Journal of Neurotrauma 21(2004)8, 1076-1089

Changes in brain metabolism associated with remission in unipolar major depression

Holthoff, V.; Beuthien-Baumann, B.; Zündorf, G.; Triemer, A.; Lüdecke, S.; Winiecki, P.; Koch, R.; Füchtner, F.; Herholz, K.

  • Acta Psychiatrica Scandinavica 110(2004), 184-194

2003

Impact of asymmetric intrauterine growth restriction on organ function in newborn piglets

Bauer, R.; Walter, B.; Brust, P.; Füchtner, F.; Zwiener, U.

  • European Journal of Obstetrics and Gynecology and Reproductive Biology 110 (2003) S40-S49

3-O-Methyl-6-[18F]Fluoro-L-DOPA and its Evaluation in Brain Tumour Imaging

Beuthien-Baumann, B.; Bredow, J.; Burchert, W.; Füchtner, F.; Bergmann, R.; Alheit, H.-D.; Reiss, G.; Hliscs, R.; Steinmeier, R.; Franke, W.-G.; Johannsen, B.; Kotzerke, J.

  • European Journal of Nuclear Medicine and Molecular Imaging (2003) 30: 1004-1008

Efficient synthesis of the 18F-labelled amino acid 3-O-methyl-6-[18F]fluoro-L-DOPA

Füchtner, F.; Steinbach, J.

  • Applied Radiation and Isotopes 58 (2003) 575-578

2002

Effect of hypoxia/hypercapnia on metabolism of 6-[18F]fluoro-L-DOPA in newborn piglets

Bauer, R.; Brust, P.; Walter, B.; Vorwieger, G.; Bergmann, R.; Elhalag, E.; Fritz, A.; Steinbach, J.; Füchtner, F.; Hinz, R.; Zwiener, U.; Johannsen, B.

  • Brain Research 934 (2002) 22-33

Distribution of estrone sulfatase in rat brain determined by in vitro autoradiography with 16alpha-[18F]fluoroestradiol-3,17beta-disulfamate

Rodig, H.; Brust, P.; Römer, J.; Kasch, H.; Bergmann, R.; Füchtner, F.; Steinbach, J.; Johannsen, B.

  • Applied Radiation and Isotopes 56 (2002) 773-780

Aspects of 6-[18F]fluoro-L-DOPA preparation: Precursor synthesis, preparative HPLC purification and determination of radiochemical purity

Füchtner, F.; Angelberger, P.; Kvaternik, H.; Hammerschmidt, F.; Peric Simovc, B.; Steinbach, J.

  • Nuclear Medicine and Biology, 29 (2002) 477-481

Distribution of 16alpha-[18F]fluoro-estradiol-3,17beta-disulfamate (FESDS) in rats, tumour-bearing mice and piglets

Brust, P.; Rodig, H.; Römer, J.; Kasch, H.; Bergmann, R.; Füchtner, F.; Zips, D.; Baumann, M.; Steinbach, J.; Johannsen, B.

  • Applied Radiation and Isotopes 57 (2002) 687-695

2001

Simultaneous preparation of 16alpha-[18F]fluoroestradiol-sulphamates in an automated module. A high-yield procedure for 16alpha-[18F]fluoroestradiol-17beta-sulphamate

Römer, J.; Füchtner, F.; Steinbach, J.; Kasch, H.

  • Poster
    14th International Symposium on Radiopharmaceutical Chemistry, Interlaken/Schweiz, 10.-15.06.2001
  • Journal of Labelled Compounds and Radiopharmaceuticals 44 (2001) 689-700

Intrauterine growth restriction induces up-regulation of cerebral aromatic amino acid decarboxylase activity in newborn piglets: [18F]fluorodopa positron-emission-tomographic study

Bauer, R.; Walter, B.; Vorwieger, G.; Bergmann, R.; Füchtner, F.; Brust, P.

  • Pediatric Research 49 (2001) 474-480

Automated Synthesis of 16alpha-[18F]fluoroestradiol-3,17beta-disulphamate

Römer, J.; Füchtner, F.; Steinbach, J.; Kasch, H.

  • Applied Radiation and Isotopes 55 (2001) 631-639.

2000

Synthesis of 16alpha-[18F]fluorestradiol-3,17beta-disulphamate

Römer, J.; Füchtner, F.; Steinbach, J.

  • J. Labelled Cpd. Radiopharm. 43 (2000) 425-436

Relation between brain tissue pO2 and dopamine synthesis of basal ganglia - A 18FDOPA-PET study in newborn piglets

Bauer, R.; Brust, P.; Walter, B.; Vorwieger, G.; Bergmann, R.; Füchtner, F.; Steinbach, J.; El-Hallag, E.; Fritz, A.; Johannsen, B.; Zwiener, U.

  • J. Perinat. Med. 28 (2000) 54-60

1999

The stability of 2-[18F]fluoro-deoxy-D-glucose towards epimerisation under alkaline conditions

Meyer, G. J.; Matzke, K. H.; Hamacher, K.; Füchtner, F.; Steinbach, J.; Notohamiprodjo, G.; Zijlstra, S.

  • Applied Radiation and Isotopes 51 (1999) 37-41

Upregulation of the Aromatic Amino Acid Decarboxylase under Neonatal Asphyxia

Brust, P.; Bauer, R.; Vorieger, G.; Walter, B.; Bergmann, R.; Füchtner, F.; Steinbach, J.; Zwiener, U.; Johannsen, B.


Long-distance transport of radionuclides between PET cyclotron and PET radiochemistry

Preusche, S.; Füchtner, F.; Steinbach, J.; Zessin, J.; Krug, H.; Neumann, W.

  • Appl. Rad. Isot. 51 (1999) 625-630

Automated Production of the PET Tracer 16 alpha-[18F] Fluoroestradiol for Breast Cancer Imaging

Römer, J.; Füchtner, F.; Steinbach, J.; Johannsen, B.

  • Nucl. Med. Biol. 26 (1999) 473-479

1998

Simultaneous Measurement of 18F-FDOPA Metabolism and Cerebral Blood Flow in Newborn Piglets

Brust, P.; Bauer, R.; Walter, B.; Bergmann, R.; Füchtner, F.; Vorwieger, G.; Steinbach, J.; Johannsen, B.; Zwiener, U.


1996

Basic Hydrolysis of 2-(18F)Fluoro-1,3,4,6-tetra-0-acetyl-D-glucose in the Preparation of 2-(18F)Fluoro-2-deoxy-D-glucose

Füchtner, F.; Steinbach, J.; Mäding, P.; Johannsen, B.


1994

N.C.A. 11C-labelling of aromatic compounds in the ring-position: synthesis of nitro-[1-11C]benzene and [1-11C]aniline

Steinbach, J.; Mäding, P.; Füchtner, F.; Johannsen, B.