Publications of Institute of Radiopharmaceutical Cancer Research

195 Publications

2024

Developing blood-brain barrier arterial spin labelling as a non-invasive early biomarker of Alzheimer’s disease (DEBBIE-AD): a prospective observational multicohort study protocol

Padrela, B.; Mahroo, A.; Tee, M.; Sneve, M. H.; Moyaert, P.; Geier, O.; Kuijer, J. P. A.; Beun, S.; Nordhøy, W.; David Zhu, Y.; Buck, M. A.; Hoinkiss, D. C.; Konstandin, S.; Huber, J.; Wiersinga, J.; Rikken, R.; de Leeuw, D.; Grydeland, H.; Tippett, L.; Cawston, E. E.; Ozturk-Isik, E.; Linn, J.; Brandt, M.; Tijms, B. M.; van de Giessen, E. M.; Muller, M.; Fjell, A.; Walhovd, K.; Bjørnerud, A.; Pålhaugen, L.; Selnes, P.; Clement, P.; Achten, E.; Anazodo, U.; Barkhof, F.; Hilal, S.; Fladby, T.; Eickel, K.; Morgan, C.; Thomas, D. L.; Petr, J.; Günther, M.; Mutsaerts, H. J. M. M.

Involved research facilities

  • PET-Center

Reproducibility of Arterial Spin Labeling Cerebral Blood Flow image processing: A Report of The ISMRM Open Science Initiative for Perfusion Imaging and the ASL MRI Challenge

Paschoal, A. M.; Woods, J. G.; Pinto, J.; Bron, E. E.; Petr, J.; Kennedy McConnell, F. A.; Bell, L.; Dounavi, M.-E.; van Praag, C. G.; Mutsaerts, H.-J.; Oliver Taylor, A.; Zhao, M. Y.; Brumer, I.; Siang Marcus Chan, W.; Toner, J.; Hu, J.; Zhang, L. X.; Domingos, C.; Monteiro, S. P.; Figueiredo, P.; Harms, A. G. J.; Padrela, B.; Tham, C.; Abdalle, A.; Croal, P. L.; Anazodo, U.

Involved research facilities

  • PET-Center

Value of [18F] FDG PET/CT parameters of the primary tumor in assessing overall survival in NSCLC patients with cN1-cN3 lymph nodes involvement

Cegla, P.; Hofheinz, F.; Czepczyński, R.; Witkowska, K.; van den Hoff, J.; Trojanowski, M.; Bos-Liedke, A.; Cholewinski, W.

Involved research facilities

  • PET-Center
  • Reports of Practical Oncology and Radiotherapy (2024)
    Online First (2024) DOI: 10.5603/rpor.99360

The Past, Present, and Future of the Brain Imaging Data Structure (BIDS)

Poldrack, R. A.; Markiewicz, C. J.; Appelhoff, S.; Ashar, Y. K.; Auer, T.; Baillet, S.; Bansal, S.; Beltrachini, L.; Bertazzoli, G.; Bhogawar, S.; Blair, R. W.; Bortoletto, M.; Boudreau, M.; Brooks, T. L.; Bénar, C. G.; Calhoun, V. D.; Castelli, F. M.; Clement, P.; Cohen, A. L.; Cohen-Adad, J.; Dambrosio, S.; Delorme, A.; Devinsky, O.; Draschkow, D.; Duff, E. P.; Dupre, E.; Earl, E.; Esteban, O.; Feingold, F. W.; Flandin, G.; Galassi, A.; Gallitto, G.; Ganz, M.; Gholam, J.; Ghosh, S. S.; Giacomel, A.; Gillman, A. G.; Gleeson, P.; Gramfort, A.; Guay, S.; Guidali, G.; Halchenko, Y. O.; Handwerker, D. A.; Hardcastle, N.; Herholz, P.; Hermes, D.; Honey, C. J.; Innis, R. B.; Ioanas, H.-I.; Jahn, A.; Karakuzu, A.; Keator, D. B.; Kiar, G.; Kincses, B.; Laird, A. R.; Lau, J. C.; Lazari, A.; Legarreta, J. H.; Li, A.; Li, X.; Love, B. C.; Lu, H.; Maumet, C.; Mazzamuto, G.; Meisler, S. L.; Mikkelsen, M.; Mutsaerts, H.; Nichols, T. E.; Nikolaidis, A.; Nilsonne, G.; Niso, G.; Norgaard, M.; Okell, T. W.; Oostenveld, R.; Ort, E.; Park, P. J.; Pawlik, M.; Pernet, C. R.; Pestilli, F.; Petr, J.; Phillips, C.; Poline, J.-B.; Pollonini, L.; Raamana, P. R.; Ritter, P.; Rizzo, G.; Robbins, K. A.; Rockhill, A. P.; Rogers, C.; Rokem, A.; Rorden, C.; Routier, A.; Saborit-Torres, J. M.; Salo, T.; Schirner, M.; Smith, R. E.; Spisak, T.; Sprenger, J.; Swann, N. C.; Szinte, M.; Takerkart, S.; Thirion, B.; Thomas, A. G.; Torabian, S.; Varoquaux, G.; Vaya, M. D. L. I.; Voytek, B.; Welzel, J.; Wilson, M.; de Hollander, G.; de la Vega, A.; Gorgolewski, K. J.

Involved research facilities

  • PET-Center

Longitudinal cerebral perfusion in presymptomatic genetic frontotemporal dementia: GENFI results

Pasternak, M.; Mirza, S.; Luciw, N.; Mutsaerts, H.; Petr, J.; Thomas, D.; Cash, D.; Bocchetta, M.; Tartaglia, C.; Mitchell, S.; Black, S.; Freedman, M.; Tang-Wai, D.; Rogaeva, E.; Russell, L.; Bouzigues, A.; van Swieten, J.; Jiskoot, L.; Seelaar, H.; Laforce Jr., R.; Tiraboschi, P.; Borroni, B.; Galimberti, D.; Rowe, J.; Graff, C.; Finger, E.; Sandro, S.; de Mendonça, A.; Butler, C.; Gerhard, A.; Sánchez-Valle, R.; Moreno, F.; Synofzik, M.; Vandenberghe, R.; Ducharme, S.; Levin, J.; Otto, M.; Santana, I.; Strafella, A.; Macintosh, B.; Rohrer, J.; Masellis, M.

Involved research facilities

  • PET-Center

Effect of physical exercise on brain perfusion in chemotherapy-treated breast cancer patients: a randomized controlled trial (PAM study)

Koevoets, E. W.; Petr, J.; Monninkhof, E. M.; Geerlings, M. I.; Witlox, L.; van der Wall, E.; Stuiver, M. M.; Sonke, G. S.; Velthuis, M. J.; Jobsen, J. J.; van der Palen, J.; Jmm Mutsaerts, H.; de Ruiter, M. B.; May, A. M.; Schagen, S. B.

Involved research facilities

  • PET-Center
  • Open Access Logo Journal of Magnetic Resonance Imaging 59(2024)5, 1667-1680
    Online First (2023) DOI: 10.1002/jmri.28967

Brain tumor imaging without gadolinium-based contrast agents: Feasible or Fantasy?

Wamelink, I. J. H. G.; Azizova, A.; Booth, T. C.; Mutsaerts, H. J. M. M.; Ogunleye, A.; Mankad, K.; Petr, J.; Barkhof, F.; Keil, V. C.

Involved research facilities

  • PET-Center

ASL lexicon and reporting recommendations: A consensus report from the ISMRM Open Science Initiative for Perfusion Imaging (OSIPI)

Suzuki, Y.; Clement, P.; Dai, W.; Dolui, S.; Fernández-Seara, M.; Lindner, T.; Mutsaerts, H. J.; Petr, J.; Shao, X.; Taso, M.; Thomas, D. L.

Involved research facilities

  • PET-Center

The Open Science Initiative for Perfusion Imaging (OSIPI): ASL Pipeline inventory

Fan, H.; Mutsaerts, H. J. M. M.; Anazodo, U.; Arteaga, D.; Baas, K. P. A.; Buchanan, C.; Camargo, A.; Keil, V. C.; Lin, Z.; Lindner, T.; Hirschler, L.; Hu, J.; Padrela, B. E.; Taghvaei, M.; Thomas, D. L.; Dolui, S.; Petr, J.

Involved research facilities

  • PET-Center

2023

Combination of tumor asphericity and an extracellular matrix-related prognostic gene signature in non-small cell lung cancer patients

Zschaeck, S.; Klinger, B.; van den Hoff, J.; Cegla, P.; Apostolova, I.; Kreissl, M.; Cholewiński, W.; Kukuk, E.; Strobel, H.; Amthauer, H.; Blüthgen, N.; Zips, D.; Hofheinz, F.

Involved research facilities

  • PET-Center

Asphericity derived from [18F]FDG PET as a new prognostic parameter in cervical cancer patients

Cegla, P.; Hofheinz, F.; Burchardt, E.; Czepczyński, R.; Kubiak, A.; van den Hoff, J.; Nikulin, P.; Bos-Liedke, A.; Roszak, A.; Cholewinski, W.

Involved research facilities

  • PET-Center

18F-FDG PET/CT-derived total lesion glycolysis predicts abscess formation in patients with surgically confirmed infective endocarditis: Results of a retrospective study at a tertiary center

Maria Sag, S. J.; Menhart, K.; Hitzenbichler, F.; Schmid, C.; Hofheinz, F.; van den Hoff, J.; Maier, L. S.; Hellwig, D.; Grosse, J.; Sag, C. M.

Involved research facilities

  • PET-Center

Radiomics predictive modeling from dual-time-point FDG PET Ki parametric maps: application to chemotherapy response in lymphoma

Samimi, R.; Shiri, I.; Ahmadyar, Y.; van den Hoff, J.; Kamali-Asl, A.; Rezaee, A.; Yousefirizi, F.; Geramifar, P.; Rahmim, A.

Involved research facilities

  • PET-Center

MRI-based parameter inference for cerebral perfusion modelling in health and ischaemic stroke

Jósza, T.; Petr, J.; Payne, S. J.; Mutsaerts, H.-J.

Involved research facilities

  • PET-Center

Genetic, vascular, and amyloid determinants of cerebral blood flow in a preclinical population

Padrela, B. E.; Lorenzini, L.; Collij, L. E.; Vállez García, D.; Coomans, E.; Ingala, S.; Tomassen, J.; Deckers, Q.; Shekari, M.; de Geus, E. J. C.; van de Giessen, E.; Ten Kate, M.; Jelle Visser, P.; Barkhof, F.; Petr, J.; Den Braber, A.; Mutsaerts, H. J. M. M.

Involved research facilities

  • PET-Center

Imaging blood-brain barrier dysfunction: A state-of-the-art review from a clinical perspective

Moyaert, P.; Padrela, B.; Morgan, C.; Petr, J.; Versijpt, J.; Barkhof, F.; Jurkiewicz, M. T.; Shao, X.; Oyeniran, O.; Manson, T.; Wang, D. J. J.; Günther, M.; Achten, E.; Mutsaerts, H. J. M. M.; Anazodo, U. C.

Involved research facilities

  • PET-Center

Advanced MR Techniques for preoperative Glioma Characterization - Part 2

Hangel, G.; Schmitz-Abecassis, B.; Sollmann, N.; Pinto, J.; Arzanforoosh, F.; Barkhof, F.; Booth, T.; Calvo-Imirizaldu, M.; Cassia, G.; Chmelik, M.; Clement, P.; Ercan, E.; Fernández-Seara, M.; Furtner, J.; Fuster-Garcia, E.; Grech-Sollars, M.; Guven, N. T.; Hatay, G. H.; Karami, G.; Keil, V.; Kim, M.; Koekkoek, J. A.; Kukran, S.; Mancini, L.; Nechifor, R. E.; Özcan, A.; Ozturk-Isik, E.; Piskin, S.; Schmainda, K.; Svensson, S.; Tseng, C. H.; Unnikrishnan, S.; Vos, S.; Warnert, E.; Zhao, M.; Jancalek, R.; Nunes, T.; Hirschler, L.; Smits, M.; Petr, J.; Emblem, K.

Involved research facilities

  • PET-Center

Advanced MR Techniques for preoperative Glioma Characterization - Part 1

Hirschler, L.; Sollmann, N.; Schmitz-Abecassis, B.; Pinto, J.; Arzanforoosh, F.; Barkhof, F.; Booth, T.; Calvo-Imirizaldu, M.; Cassia, G.; Chmelik, M.; Clement, P.; Ercan, E.; Fernández-Seara, M.; Furtner, J.; Fuster-Garcia, E.; Grech-Sollars, M.; Guven, N. T.; Hatay, G. H.; Karami, G.; Keil, V.; Kim, M.; Koekkoek, J. A. F.; Kukran, S.; Mancini, L.; Nechifor, R. E.; Özcan, A.; Ozturk-Isik, E.; Piskin, S.; Schmainda, K.; Svensson, S.; Tseng, C. H.; Unnikrishnan, S.; Vos, S.; Warnert, E.; Zhao, M.; Jancalek, R.; Nunes, T.; Emblem, K.; Smits, M.; Petr, J.; Hangel, G.

Involved research facilities

  • PET-Center

A convolutional neural network with self-attention for fully automated metabolic tumor volume delineation of head and neck cancer in [18F]FDG PET/CT

Nikulin, P.; Zschaeck, S.; Maus, J.; Cegla, P.; Lombardo, E.; Furth, C.; Kaźmierska, J.; Rogasch, J.; Holzgreve, A.; Albert, N. L.; Ferentinos, K.; Strouthos, I.; Hajiyianni, M.; Marschner, S. N.; Belka, C.; Landry, G.; Cholewinski, W.; Kotzerke, J.; Hofheinz, F.; van den Hoff, J.

Involved research facilities

  • PET-Center

Current state and Guidance on Arterial Spin Labeling Perfusion MRI in Clinical Neuroimaging

Lindner, T.; Bolar, D. S.; Achten, E.; Barkhof, F.; Bastos-Leite, A. J.; Detre, J. A.; Golay, X.; Günther, M.; Wang, D. J.; Haller, S.; Ingala, S.; Jäger, H. R.; Jahng, G.-H.; Juttukonda, M. R.; Keil, V. C.; Kimura, H.; Ho, M.-L.; Lequin, M.; Lou, X.; Petr, J.; Pinter, N.; Pizzini, F. B.; Smits, M.; Sokolska, M.; Zaharchuk, G.; Mutsaerts, H. J.

Involved research facilities

  • PET-Center

The value of arterial spin labelling perfusion MRI in brain age prediction

Dijsselhof, M.; Barboure, M.; Stritt, M.; Nordhøy, W.; Wink, A. M.; Beck, D.; Westlye, L. T.; Cole, J. H.; Barkhof, F.; Mutsaerts, H. J. M. M.; Petr, J.

Involved research facilities

  • PET-Center

Reproducibility of 3T APT-CEST in healthy volunteers and brain glioma patients

Wamelink, I. J. H. G.; Kuijer, J. P. A.; Padrela, B. E.; Zhang, Y.; Barkhof, F.; Mutsaerts, H. J. M. M.; Petr, J.; van de Giessen, E.; Keil, V. C.

Involved research facilities

  • PET-Center

2022

Development of a neurotensin-derived 68Ga-labeled PET ligand with high in vivo stability for imaging of NTS1 receptor-expressing tumors

Schindler, L.; Moosbauer, J.; Schmidt, D.; Spruss, T.; Grätz, L.; Lüdeke, S.; Hofheinz, F.; Meister, S.; Echtenacher, B.; Bernhardt, G.; Pietzsch, J.; Hellwig, D.; Keller, M.

The Open-Access European Prevention of Alzheimer’s Dementia (EPAD) MRI dataset and processing workflow

Lorenzini, L.; Ingala, S.; Wink, A. M.; Kuijer, J. P. A.; Wottschel, V.; Dijsselhof, M.; Sudre, C. H.; Haller, S.; Molinuevo, J. L.; Gispert, J. D.; Cash, D. M.; Thomas, D. L.; Vos, S. B.; Prados, F.; Petr, J.; Wolz, R.; Palombit, A.; Schwarz, A. J.; Chételat, G.; Payoux, P.; Di Perri, C.; Wardlaw, J. M.; Frisoni, G. B.; Foley, C.; Fox, N. C.; Ritchie, C.; Pernet, C.; Waldman, A.; Barkhof, F.; Mutsaerts, H. J. M. M.

Involved research facilities

  • PET-Center

Recent technical developments in ASL: A Review of the State of the Art

Hernandez-Garcia, L.; Aramendia, V.; Dai, W.; Bolar, D.; Fernández-Seara, M. A.; Guo, J.; Madhuranthakam, A. J.; Mutsaerts, H.; Petr, J.; Qin, Q.; Schollenberger, J.; Suzuki, Y.; Taso, M.; Thomas, D. L.; van Osch, M. J. P.; Woods, J.; Zhao, M. Y.; Yan, L.; Wang, Z.; Zhao, L.; Okell, T. W.

Involved research facilities

  • PET-Center

Correlation Between Quantitative PSMA PET Parameters and Clinical Risk Factors in Non-Metastatic Primary Prostate Cancer Patients

Zschaeck, S.; Andela, S. B.; Amthauer, H.; Furth, C.; Rogasch, J. M.; Beck, M.; Hofheinz, F.; Huang, K.

Involved research facilities

  • PET-Center

A Beginner’s Guide to Arterial Spin Labeling (ASL) Image Processing

Clement, P.; Petr, J.; Dijsselhof, M. B.; Padrela, B.; Pasternak, M.; Dolui, S.; Jarutyte, L.; Pinter, N.; Hernandez Garcia, L.; Jahn, A.; Kuijer, J. P.; Barkhof, F.; Mutsaerts, H. J.; Keil, V. C.

Involved research facilities

  • PET-Center

Atherosclerotic risk is associated with cerebral perfusion – a cross-sectional study using arterial spin labelling MRI

Hafdi, M.; Mutsaerts, H. J.; Petr, J.; Richard, E.; van Dalen, J. W.

Involved research facilities

  • PET-Center

Comparison of Image Quality and Spatial Resolution Between 18F, 68Ga and 64Cu Phantom Measurements Using a Digital Biograph Vision PET/CT

Braune, A.; Oehme, L.; Freudenberg, R.; Hofheinz, F.; van den Hoff, J.; Kotzerke, J.; Hoberück, S.

Involved research facilities

  • PET-Center

Influences on PET Quantification and Interpretation

Rogasch, J.; Hofheinz, F.; van Heek, L.; Voltin, C.; Boellaard, R.; Kobe, C.

Involved research facilities

  • PET-Center

ASL-BIDS, the brain imaging data structure extension for arterial spin labeling

Clement, P.; Castellaro, M.; Okell, T. W.; Thomas, D. L.; Vandemaele, P.; Elgayar, S.; Oliver-Taylor, A.; Kirk, T.; Woods, J. G.; Vos, S.; Kuijer, J. P. A.; Achten, E.; van Osch, M. J. P.; Gau, R.; Detre, J.; Lu, H.; Alsop, D. C.; Chappell, M. A.; Hernandez-Garcia, L.; Petr, J.; Mutsaerts, H. J. M. M.

Involved research facilities

  • PET-Center

Arterial Spin-Labeling Parameters and Their Associations with Risk Factors, Cerebral Small-Vessel Disease, and Etiologic Subtypes of Cognitive Impairment and Dementia

Gyanwali, B.; Seng Tan, C.; Petr, J.; Tirado Escobosa, L. L.; Vrooman, H.; Chen, C.; Mutsaerts, H. J. M. M.; Hilal, S.

Involved research facilities

  • PET-Center

Association of arterial spin labeling parameters with cognitive decline, vascular events and mortality in a memory-clinic sample

Gyanwali, B.; Mutsaerts, H. J. M. M.; Seng Tan, C.; Rajab Kaweilh, O.; Petr, J.; Chen, C.; Hilal, S.

Involved research facilities

  • PET-Center

Cerebral perfusion and the risk for cognitive decline and dementia in community dwelling older people

Abdulrahman, H.; Hafdi, M.; Mutsaerts, H. J. M. M.; Nederveen, A. J.; Petr, J.; Gool, W. A. V.; Richard, E.; Dalen, J. V.

Involved research facilities

  • PET-Center

“Clickable” albumin binders for modulating the tumor uptake of targeted radiopharmaceuticals

Brandt, F.; Ullrich, M.; Laube, M.; Kopka, K.; Bachmann, M.; Löser, R.; Pietzsch, J.; Pietzsch, H.-J.; van den Hoff, J.; Wodtke, R.

Involved research facilities

  • PET-Center

Related publications

A systematic review on the use of quantitative imaging to detect cancer therapy adverse effects in normal-appearing brain tissue

Petr, J.; Hogeboom, L.; Nikulin, P.; Wiegers, E.; Schroyen, G.; Kallehauge, J.; Chmelik, M.; Clement, P.; Nechifor, R. E.; Fodor, L.-A.; de Witt Hamer, P.; Barkhof, F.; Pernet, C.; Lequin, M.; Deprez, S.; Jancalek, R.; Mutsaerts, H. J.; Pizzini, F. B.; Emblem, K. E.; Keil, V. C.

Involved research facilities

  • PET-Center

Overestimation of grey matter atrophy in glioblastoma patients following radio(chemo)therapy

Gommlich, A.; Raschke, F.; Petr, J.; Seidlitz, A.; Jentsch, C.; Platzek, I.; van den Hoff, J.; Kotzerke, J.; Beuthien-Baumann, B.; Baumann, M.; Krause, M.; Troost, E. G. C.

Cerebral blood flow of the frontal lobe in untreated children with trigonocephaly vs healthy controls: an arterial spin labeling study

de Planque, C. A.; Petr, J.; Gaillard, L.; Mutsaerts, H. J.; van Veelen, M. L. C.; Versnel, S. L.; Dremmen, M.; Mathijssen, I. M. J.

Involved research facilities

  • PET-Center

2021

Prognostic Value of Pretherapeutic Primary Tumour MTV from [18F]FDG PET in Radically Treated Cervical Cancer Patients

Cegla, P.; Hofheinz, F.; CholewińSki, W.; Czepczynski, R.; Kubiak, A.; van den Hoff, J.; Bos-Liedke, A.; Roszak, A.; Ewa Burchardt, E.

Involved research facilities

  • PET-Center

Final Results of the Prospective Biomarker Trial PETra: [11C]-MET-Accumulation in Postoperative PET/MRI Predicts Outcome after Radiochemotherapy in Glioblastoma

Seidlitz, A.; Beuthien-Baumann, B.; Löck, S.; Jentsch, C.; Platzek, I.; Zöphel, K.; Linge, A.; Kotzerke, J.; Petr, J.; van den Hoff, J.; Steinbach, J.; Krex, D.; Schmitz-Schackert, G.; Falk, M.; Baumann, M.; Krause, M.

Involved research facilities

  • PET-Center

Epileptogenic zone detection in MRI negative epilepsy using adaptive thresholding of arterial spin labeling data

Gajdoš, M.; Říha, P.; Kojan, M.; Doležalová, I.; Mutsaerts, H. J. M. M.; Petr, J.; Rektor, I.

Involved research facilities

  • PET-Center

Using perfusion contrast for spatial normalization of ASL MRI images in a pediatric craniosynostosis population

de Planque, C. A.; Mutsaerts, H. J. M. M.; Keil, V. C. W.; Erler, N. S.; Dremmen, M. H. G.; Mathijssen, I. M. J.; Petr, J.

Involved research facilities

  • PET-Center

From research to clinical practice: a European neuroradiological survey on quantitative advanced MRI implementation

Manfrini, E.; Smits, M.; Thust, S.; Geiger, S.; Bendella, Z.; Petr, J.; Solymosi, L.; Keil, V. C.

Involved research facilities

  • PET-Center

Effects of Acquisition Parameter Modifications and Field Strength on the Reproducibility of Brain Perfusion Measurements Using Arterial Spin-Labeling

Baas, K.; Petr, J.; Kuijer, J.; Nederveen, A.; Mutsaerts, H.-J.; van de Ven, K.

Involved research facilities

  • PET-Center

GliMR: Cross-border collaborations to promote advanced MRI biomarkers in glioma

Clement, P.; Borovecki, F.; Emblem, K. E.; Figueiredo, P.; Hirschler, L.; Jancalek, R.; Keil, V. C.; Maumet, C.; Ozsunar, Y.; Pernet, C.; Petr, J.; Pinto, J.; Smits, M.; Warnert, E. A. H.

Involved research facilities

  • PET-Center

A convolutional neural network for fully automated blood SUV determination to facilitate SUR computation in oncological FDG-PET

Nikulin, P.; Hofheinz, F.; Maus, J.; Li, Y.; Bütof, R.; Lange, C.; Furth, C.; Zschaeck, S.; Kreissl, M. C.; Kotzerke, J.; van den Hoff, J.

Involved research facilities

  • PET-Center

Antihypertensive use differentially associated with lower cerebral blood flow in older people with hypertension

van Dalen, J. W.; Mutsaerts, H. J.; Petr, J.; Caan, M. W.; Moll Van Charante, E. P.; Macintosh, B. J.; van Gool, W. A.; Nederveen, A. J.; Richard, E.

Involved research facilities

  • PET-Center

Dose dependent cerebellar atrophy in glioma patients after radio(chemo)therapy

Raschke, F.; Seidlitz, A.; Wesemann, T.; Löck, S.; Jentsch, C.; Platzek, I.; Petr, J.; van den Hoff, J.; Kotzerke, J.; Beuthien-Baumann, B.; Baumann, M.; Linn, J.; Krause, M.; Troost, E. G. C.

The effects of intracranial stenosis on cerebral perfusion and cognitive performance

Hilal, S.; Mutsaerts, H. J. M. M.; Ferro, D. A.; Petr, J.; Kuijf, H.; Biessels, G. J.; Chen, C. P. L. H.

Involved research facilities

  • PET-Center

Hemodynamic impairments within individual watershed areas in asymptomatic carotid artery stenosis by multimodal MRI

Kaczmarz, S.; Goettler, J.; Petr, J.; Hansen, M. B.; Mouridsen, K.; Zimmer, C.; Hyder, F.; Preibisch, C.

Involved research facilities

  • PET-Center

2020

PET measured hypoxia and MRI parameters in re-irradiated head and neck squamous cell carcinomas: findings of a prospective pilot study

Rogasch, J.; Beck, M.; Stromberger, C.; Hofheinz, F.; Ghadjar, P.; Wust, W.; Budach, V.; Amthauer, H.; Tinhofer, I.; Furth, C.; Walter-Rittel, T.; Zschaeck, S.

Involved research facilities

  • PET-Center

KRAS mutation effects on the 2-[18F]FDG PET uptake of colorectal adenocarcinoma metastases in the liver

Popovic, M.; Talarico, O.; van den Hoff, J.; Kunin, H.; Zhang, Z.; Lafontaine, D.; Dogan, S.; Leung, J.; Kaye, E.; Czmielewski, C.; Et Al, S.

Involved research facilities

  • PET-Center

Short-duration dynamic FDG PET imaging: Optimization and clinical application

Samimi, R.; Kamali-Asl, A.; Geramifar, P.; van den Hoff, J.; Rahmim, A.

Involved research facilities

  • PET-Center

Asphericity of tumor FDG uptake in non-small cell lung cancer: Reproducibility and implications for harmonization in multicenter studies

Rogasch, J.; Furth, C.; Bluemel, S.; Radojewski, P.; Amthauer, H.; Hofheinz, F.

Involved research facilities

  • PET-Center

A FDG-PET radiomics signature detects esophageal squamous cell carcinoma patients who do not benefit from chemoradiation

Li, Y.; Beck, M.; Päßler, T.; Lili, C.; Wu, H.; Ha, D.; Amthauer, H.; Biebl, M.; Thuss-Patience, P.; Berger, J.; Stromberger, C.; Tinhofer, I.; Kruppa, J.; Budach, V.; Hofheinz, F.; Lin, Q.; Zschaeck, S.

Involved research facilities

  • PET-Center

Prognostic value of baseline [18F]-fluorodeoxyglucose positron emission tomography parameters MTV, TLG and asphericity in an international multicenter cohort of nasopharyngeal carcinoma patients

Zschaeck, S.; Li, Y.; Lin, Q.; Beck, M.; Amthauer, H.; Bauersachs, L.; Hajiyianni, M.; Rogasch, J.; Ehrhardt, V. H.; Kalinauskaite, G.; Weingärtner, J.; Hartmann, V.; van den Hoff, J.; Budach, V.; Stromberger, C.; Hofheinz, F.

Involved research facilities

  • PET-Center

Combined tumor plus nontumor interim FDG‐PET parameters are prognostic for response to chemoradiation in squamous cell esophageal cancer

Zschaeck, S.; Li, Y.; Bütof, R.; Lili, C.; Hua, W.; Troost, E.; Beck, M.; Amthauer, H.; Kaul, D.; Kotzerke, J.; Baur, A.; Ghadjar, P.; Baumann, M.; Krause, M.; Hofheinz, F.

Involved research facilities

  • PET-Center

Reconstructed spatial resolution and contrast recovery with Bayesian penalized likelihood reconstruction (Q.Clear) for FDG-PET compared to time-of-flight (TOF) with point spread function (PSF)

Rogasch, J.; Suleiman, S.; Hofheinz, F.; Bluemel, S.; Lukas, M.; Amthauer, H.; Furth, C.

Involved research facilities

  • PET-Center

Olfactory dysfunction correlates with putaminal dopamine turnover in early de novo Parkinson’s disease

Löhle, M.; Wolz, M.; Beuthien-Baumann, B.; Oehme, L.; van den Hoff, J.; Kotzerke, J.; Reichmann, H.; Storch, A.

Involved research facilities

  • PET-Center

Individual patient data meta-analysis of FMISO and FAZA hypoxia PET scans from head and neck cancer patients undergoing definitive radio-chemotherapy

Zschaeck, S.; Löck, S.; Hofheinz, F.; Zips, D.; Mortensen, L.; Zöphel, K.; Troost, E. G. C.; Boeke, D.; Saksoe, M.; Mönnich, D.; Seidlitz, A.; Johansen, J.; Skripcak, T.; Gregoire, V.; Overgaard, J.; Baumann, M.; Krause, M.

Involved research facilities

  • PET-Center

Accurate MR image registration to anatomical reference space for diffuse glioma

Visser, M.; Petr, J.; Müller, D. M.; Eijgelaar, R. S.; Hendriks, E. J.; Witte, M.; Barkhof, F.; van Herk, M.; Mutsaerts, H. J.; de Munck, J. C.; Vrenken, H.; de Witt Hamer, P. C.

Involved research facilities

  • PET-Center

The sigma-1 receptor: potential role in the modulation of cellular radiation sensitivity

Belter, B.; Deuther-Conrad, W.; Hofheinz, F.; Bachmann, M.; Brust, P.; Pietzsch, J.

Cerebral Oxygen Metabolism in Adults with Sickle Cell Disease

Václavů, L.; Petr, J.; Petersen, E. T.; Mutsaerts, H. J. M. M.; Majoie, C. B. L.; Wood, J. C.; Vanbavel, E.; Nederveen, A. J.; Biemond, B. J.

Involved research facilities

  • PET-Center

ExploreASL: an image processing pipeline for multi-center ASL perfusion MRI studies

Mutsaerts, H. J.; Petr, J.; Groot, P. F.; Vandemaele, P.; Ingala, S.; Robertson, A. D.; Vaclavu, L.; Groote, I.; Kuijf, H.; Zelaya, F.; O'Daly, O.; Hilal, S.; Wink, A. M.; Kant, I.; Caan, M.; Morgan, C.; de Bresser, J.; Lysvik, E.; Schrantee, A.; Bjornebekk, A.; Clement, P.; Shirzadi, Z.; Kuijer, J.; Anazodo, U.; Pajkrt, D.; Richard, E.; Bokkers, R.; Reneman, L.; Masellis, M.; Guenther, M.; Macintosh, B.; Achten, E.; Chappell, M.; van Osch, M.; Golay, X.; Thomas, D.; de Vita, E.; Bjornerud, A.; Nederveen, A.; Hendrikse, J.; Asllani, I.; Barkhof, F.

Involved research facilities

  • PET-Center

Validation of an independent prognostic value of the asphericity of F18-fluorodeoxyglucose (FDG) uptake in non-small cell lung cancer (NSCLC) patients undergoing treatment in curative intent

Rogasch, J.; Furth, C.; Chibolela, C.; Hofheinz, F.; Ochsenreither, S.; Rückert, J.; Neudecker, J.; Böhmer, D.; Laffert, M.; Amthauer, H.; Frost, N.

Involved research facilities

  • PET-Center

Spatial Coefficient of Variation of Arterial Spin Labeling MRI as a Cerebrovascular Correlate of Carotid Occlusive Disease

Mutsaerts, H. J. M. M.; Petr, J.; Bokkers, R. P. H.; Lazar, R. M.; Marshall, R. S.; Asllani, I.

Involved research facilities

  • PET-Center

Cortical microinfarcts in memory clinic patients are associated with reduced cerebral perfusion

Ferro, D.; Mutsaerts, H.; Hilal, S.; Kuijf, H.; Petersen, E. T.; Petr, J.; van Veluw, S.; Venketasubramanian, N.; Yeow, T. B.; Biessels, G. J.; Chen, C.

Involved research facilities

  • PET-Center

2019

Correlation between FMISO-PET based hypoxia in the primary tumour and in lymph node metastases in locally advanced HNSCC patients

Bandurska-Luque, A.; Löck, S.; Haase, R.; Richter, C.; Zöphel, K.; Perrin, R.; Appold, S.; Krause, M.; Steinbach, J.; Kotzerke, J.; Hofheinz, F.; Zips, D.; Baumann, M.; Troost, E. G. C.

Involved research facilities

  • PET-Center

Confirmation of the prognostic value of pretherapeutic tumor SUR and MTV in patients with esophageal squamous cell carcinoma

Hofheinz, F.; Li, Y.; Steffen, I.; Lin, Q.; Lili, C.; Hua, W.; van den Hoff, J.; Zschaeck, S.

Involved research facilities

  • PET-Center

Comparison of Static and Dynamic 18F-FDG PET/CT for Quantification of Pulmonary Inflammation in Acute Lung Injury

Braune, A.; Hofheinz, F.; Bluth, T.; Kiss, T.; Wittenstein, J.; Scharffenberg, M.; Kotzerke, J.; Gama De Abreu, M.

Involved research facilities

  • PET-Center

Biomaterials in repairing rat femoral defects: in vivo insights from small animal positron emission tomography/computed tomography (PET/CT) studies

Neuber, C.; Schulze, S.; Förster, Y.; Hofheinz, F.; Wodke, J.; Möller, S.; Schnabelrauch, M.; Hintze, V.; Scharnweber, D.; Rammelt, S.; Pietzsch, J.

The association of intra-therapeutic heterogeneity of somatostatin receptor expression with morphological treatment response in patients undergoing PRRT with [177Lu]-DOTATATE

Wetz, C.; Genseke, P.; Apostolova, I.; Furth, C.; Ghazzawi, S.; Rogasch, J.; Schatka, I.; Kreissl, M.; Hofheinz, F.; Grosser, O.; Amthauer, H.

Involved research facilities

  • PET-Center

Late life brain perfusion after prenatal famine exposure

de Rooij, S. R.; Mutsaerts, H. M.; Petr, J.; Asllani, I.; Caan, M. W.; Groot, P.; Nederveen, A.; Schwab, M.; Roseboom, T. J.

Involved research facilities

  • PET-Center

Interobserver variability of image-derived arterial blood SUV in whole-body FDG PET

Hofheinz, F.; Maus, J.; Zschaeck, S.; Rogasch, J.; Schramm, G.; Oehme, L.; Apostolova, I.; Kotzerke, J.; van den Hoff, J.

Involved research facilities

  • PET-Center

Time efficient scatter correction for time-of-flight PET: the immediate scatter approximation

Nikulin, P.; Maus, J.; Hofheinz, F.; Lougovski, A.; van den Hoff, J.

Involved research facilities

  • PET-Center

FDG-PET/MRI in patients with pelvic recurrence of rectal cancer: first clinical experiences

Plodeck, V.; Rahbari, N.; Weitz, J.; Radosa, C.; Laniado, M.; Hoffmann, R.; Zoephel, K.; Beuthien-Baumann, B.; Kotzerke, J.; van den Hoff, J.; Platzek, I.

Involved research facilities

  • PET-Center

Cerebral perfusion changes in presymptomatic genetic frontotemporal dementia: a GENFI study

Mutsaerts, H. J. M. M.; Mirza, S. S.; Petr, J.; Thomas, D. L.; Cash, D. M.; Bocchetta, M.; de Vita, E.; Metcalfe, A. W.; Shirzadi, Z.; Robertson, A. D.; Carmela Tartaglia, M.; Mitchell, S. B.; Black, S. E.; Freedman, M.; Tang-Wai, D.; Keren, R.; Rogaeva, E.; van Swieten, J.; Laforce, R. J.; Tagliavini, F.; Borroni, B.; Galimberti, D.; Rowe, J. B.; Graff, C.; Frisoni, G. B.; Finger, E.; Sorbi, S.; de Mendonça, A.; Rohrer, J. D.; Macintosh, B. J.; Masellis, M.

Involved research facilities

  • PET-Center

Prognostic value of SUR in patients with trimodality treatment of locally advanced esophageal carcinoma

Bütof, R.; Hofheinz, F.; Zöphel, K.; Schmollack, J.; Jentsch, C.; Zschaeck, S.; Kotzerke, J.; van den Hoff, J.; Michael Baumann, M.

Involved research facilities

  • PET-Center

2018

Pretherapeutic FDG–PET total metabolic tumor volume predicts response to induction therapy in pediatric Hodgkin’s lymphoma

Rogasch, J.; Hundsdoerfer, P.; Hofheinz, F.; Wedel, F.; Schatka, I.; Amthauer, H.; Furth, C.

Involved research facilities

  • PET-Center

In vivo confirmation of altered hepatic glucose metabolism in patients with liver fibrosis/cirrhosis by 18F-FDG PET/CT

Verloh, N.; Einspieler, I.; Utpatel, K.; Menhart, K.; Brunner, S.; Hofheinz, F.; van den Hoff, J.; Wiggermann, P.; Evert, M.; Stroszczynski, C.; Hellwig, D.; Grosse, J.

Involved research facilities

  • PET-Center

Cerebrovascular Reactivity during Prolonged Breath-Hold in Experienced Freedivers

Keil, V.; Eichhorn, L.; Mutsaerts, H.; Träber, F.; Block, W.; Mädler, B.; van de Ven, K.; Siero, J.; Macintosh, B.; Petr, J.; Fimmers, R.; Schild, H.; Hattingen, E.

Involved research facilities

  • PET-Center

Monitoring scanner calibration using the image derived arterial blood SUV in whole-body FDG-PET

Maus, J.; Hofheinz, F.; Apostolova, I.; Kreissl, M. C.; Kotzerke, J.; van den Hoff, J.

Involved research facilities

  • PET-Center

Related publications

Increased evidence for the prognostic value of late-treatment FDG-PET uptake in non-tumor affected oesophagus in irradiated patients with oesophageal carcinomas

Li, Y.; Hofheinz, F.; Furth, C.; Lili, C.; Hua, W.; Ghadjar, P.; Zschaeck, S.

Involved research facilities

  • PET-Center

Effects of systematic partial volume errors on the computation of mean gray matter cerebral blood flow with Arterial Spin Labeling MRI

Petr, J.; Mutsaerts, H. J. M. M.; de Vita, E.; Steketee, R. M. E.; Smits, M.; Nederveen, A. J.; Hofheinz, F.; van den Hoff, J.; Asllani, I.

Involved research facilities

  • PET-Center

Overexpression of receptor tyrosine kinase EphB4 triggers tumor growth and hypoxia in A375 melanoma xenografts: insights from multitracer small animal imaging experiments

Neuber, C.; Belter, B.; Meister, S.; Hofheinz, F.; Bergmann, R.; Pietzsch, H.-J.; Pietzsch, J.

Photon vs. proton radiochemotherapy: effects on brain tissue volume and perfusion

Petr, J.; Platzek, I.; Hofheinz, F.; Mutsaerts, H.; Asllani, I.; van Osch, M.; Seidlitz, A.; Krukowski, P.; Gommlich, A.; Beuthien-Baumann, B.; Jentsch, C.; Maus, J.; Troost, E.; Baumann, M.; Krause, M.; van den Hoff, J.

Involved research facilities

  • PET-Center

Comparison of arterial spin labeling registration strategies in the multi-center GENetic frontotemporal dementia initiative (GENFI)

Mutsaerts, H. J. M. M.; Petr, J.; Thomas, D. L.; de Vita, E.; Cash, D. M.; van Osch, M. J. P.; Golay, X.; Groot, P. F. C.; Ourselin, S.; van Swieten, J.; Laforce, R.; Tagliavini, F.; Borroni, B.; Galimberti, D.; Rowe, J. B.; Graff, C.; D. Pizzini, F. B.; Finger, E.; Sorbi, S.; Castelo Branco, M.; Rohrer, J. D.; Masellis, M.; Macintosh, B. J.

Involved research facilities

  • PET-Center

2017

Quantification: there is more to worry about than good scanner hardware and reliable calibration

Kotzerke, J.; van den Hoff, J.

Involved research facilities

  • PET-Center

Nitric oxide-releasing selective cyclooxygenase-2 inhibitors as promising radiosensitizers in melanoma cells in vitro

Bechmann, N.; Hauser, S.; Hofheinz, F.; Kniess, T.; Pietzsch, J.

Involved research facilities

  • PET-Center
  • Open Access Logo Annals of Radiation Therapy and Oncology 1(2017)2, 1010

Potential of asphericity as a novel diagnostic parameter in the evaluation of patients with Ga-68-PSMA-HBED-CC PET-positive prostate cancer lesions

Meissner, S.; Janssen, J.; Prasad, V.; Brenner, W.; Diederichs, G.; Hamm, B.; Hofheinz, F.; Makowski, M.

Involved research facilities

  • PET-Center

Individualized risk assessment in neuroblastoma: does the tumoral metabolic activity on 123I-MIBG SPECT predict the outcome?

Rogasch, J.; Hundsdoerfer, P.; Furth, C.; Wedel, F.; Hofheinz, F.; Krüger, P.; Lode, H.; Brenner, W.; Eggert, A.; Amthauer, H.; Schatka, I.

Involved research facilities

  • PET-Center

Increased FDG uptake on late-treatment PET in non-tumour-affected oesophagus is prognostic for pathological complete response and disease recurrence in patients undergoing neoadjuvant radiochemotherapy

Zschaeck, S.; Hofheinz, F.; Zöphel, K.; Bütof, R.; Jentsch, C.; Schmollack, J.; Löck, S.; Kotzerke, J.; Baretton, G.; Weitz, J.; Baumann, M.; Krause, M.

Involved research facilities

  • PET-Center

Test-retest variability of lesion SUV and lesion SUR in 18F-FDG PET: an analysis of data from two prospective multicenter trials

Hofheinz, F.; Apostolova, I.; Oehme, L.; Kotzerke, J.; van den Hoff, J.

Involved research facilities

  • PET-Center

FDG PET/MR in initial staging of sarcoma: Initial experience and comparison with conventional imaging

Platzek, I.; Beuthien-Baumann, B.; Schramm, G.; Maus, J.; Laniado, M.; Kotzerke, J.; van den Hoff, J.; Schuler, M.

Involved research facilities

  • PET-Center

The spatial coefficient of variation in arterial spin labeling cerebral blood flow images

Mutsaerts, H. J.; Petr, J.; Václavů, L.; van Dalen, J. W.; Robertson, A. D.; Caan, M. W.; Masellis, M.; Nederveen, A. J.; Richard, E.; Macintosh, B. J.

Involved research facilities

  • PET-Center

Predictive Value of Asphericity in Pretherapeutic [111In]DTPA-Octreotide SPECT/CT for Response to Peptide Receptor Radionuclide Therapy with [177Lu]DOTATATE

Wetz, C.; Apostolova, I.; Steffen, I. G.; Hofheinz, F.; Furth, C.; Kupitz, D.; Ruf, J.; Venerito, M.; Klose, S.; Amthauer, H.

Involved research facilities

  • PET-Center

2016

Moments-based ultrasound visual servoing: from mono to multi-plane approach

Nadeau, C.; Krupa, A.; Petr, J.; Barillot, C.

Involved research facilities

  • PET-Center

The asphericity of the metabolic tumour volume in NSCLC: correlation with histopathology and molecular markers

Apostolova, I.; Ego, K.; Steffen, I. G.; Buchert, R.; Wertzel, H.; Achenbach, J.; Riedel, S.; Schreiber, J.; Schultz, M.; Furth, C.; Derlin, T.; Amthauer, H.; Hofheinz, F.; Kalinski, T.

Involved research facilities

  • PET-Center

Comparative evaluation of SUV, tumor-to-blood standard uptake ratio (SUR), and dual time point measurements for assessment of the metabolic uptake rate in FDG PET

Hofheinz, F.; van den Hoff, J.; Steffen, I. G.; Lougovski, A.; Ego, K.; Amthauer, H.; Apostolova, I.

Involved research facilities

  • PET-Center

Putaminal dopamine turnover in de novo Parkinson disease predicts later motor complications

Loehle, M.; Mende, J.; Wolz, M.; Beuthien-Baumann, B.; Oehme, L.; van den Hoff, J.; Kotzerke, J.; Reichmann, H.; Storch, A.

Involved research facilities

  • PET-Center

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