Publications of Institute of Radiopharmaceutical Cancer Research

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219 Publications

1999

Synthesis and preliminary pharmacological investigations of 1-(1,2-dihydro-2-acenaphthylenyl)piperazine derivatives as potential atypical antipsychotic agents in mice

Srinivas, P.; Subramanian, A. R.; Brust, P.; Raghavan, S. A. V.; Rangisetty, J. B.; et al. (9 authors)

IL FARMACO 54 (1999) 567-572
DOI: 10.1016/S0014-827X(99)00058-0

Synthesis and Autoradiographical Evaluation of a Novel High-Affinity Tc-99m Ligand for the 5-HT_2A Receptor

Pietzsch, H.-J.; Scheunemann, M.; Kretzschmar, M.; Elz, S.; Pertz, H. H.; et al. (10 authors)

Nuclear Medicine and Biology, 26 (1999) 865-875

Synthesis and preliminary binding affinities of 1(1,2-dihydro-2-acenaphthylenyl)piperazine - a new arylpiperazine

Srinivas, P.; Brust, P.; Subramanian, A. R.; Raghavan, S. A. V.; Rangisetty, J. B.; et al. (7 authors)Gupta, C. N. V. H. B.; Parimoo, P.

Pharmaceutica Acta Helvetiae 74 (1999) 73-73
DOI: 10.1016/S0031-6865(99)00019-9

Efficient Synthesis of Enantiomerically Pure Thioester Precursors of [¹¹C] MCN-5652 from Racemic MCN-5652

Zessin, J.; Gucker, P.; Ametamey, S. M.; Steinbach, J.; Brust, P.; et al. (8 authors)

J. Labelled Cpd. Radiopharm. 42 (1999) 1301-1312

Radioligands for the Study of the 5-HT Transporter in Vivo

Brust, P.; Scheffel, U.; Szabo, Z.

IDrugs 1999 Vol 2 No 2 , Review Radioligands 129-145

1998

TROTEC-1 a new high affinity ligand for Labeling of the dopamine transporter

Hoepping, A.; Reisgys, M.; Brust, P.; Seifert, S.; Spies, H.; et al. (7 authors)Alberto, R.; Johannsen, B.

Journal of Medicinal Chemistry, 41(23) (1998) 4429-4432
DOI: 10.1021/jm981008a

Functional expression of the serotonin transporter in immortalized rat brain microvessel endothelial cells

Brust, P.; Friedrich, A.; Krizbai, I. A.; Bergmann, R.; Roux, F.; et al. (7 authors)Ganapathy, V.; Johannsen, B.

J.Neurochem. 74, (2000) 1241-1248
Journal of Cerebral Blood Flow and Metabolism, Vol. 19 (Suppl.1), 245
DOI: 10.1046/j.1471-4159.2000.741241.x

Differentiation Between Specific and Nonspecific Effects Related to P-Glycoprotein Inhibition in Immortalized Rat Brain Endothelial Cells

Bergmann, R.; Brust, P.; Johannsen, B.

International Journal of Clinical Pharmacology and Therapeutics, Vol. 36, No. 1, 1998 (46-49)

Simultaneous Measurement of ¹⁸F-FDOPA Metabolism and Cerebral Blood Flow in Newborn Piglets

Brust, P.; Bauer, R.; Walter, B.; Bergmann, R.; Füchtner, F.; et al. (9 authors)

Int. J. Devl. Neuroscience, Vol. 16, No. 5, pp 353-364, 1998
DOI: 10.1016/S0736-5748(98)00017-3

Novel Rhenium Complexes Derived from ALPHA-Tropanol as Potential Ligands for the Dopamin Transporter

Hoepping, A.; Brust, P.; Berger, R.; Leibnitz, P.; Spies, H.; et al. (8 authors)

Bioorganic & Medicinal Chemistry 6 (1998) 1663-1672
DOI: 10.1016/S0968-0896(98)00144-8

1997

Different response of cerebral and non-cerebral endothelial cells to cytotoxic hypoxia

Ahlemeyer, B.; Brust, P.; Johannsen, B.

Neurochem. Int. 31 (1997) 39-44

Structural modification of receptor binding 99m-Tc complexes in order to improve brain uptake

Johannsen, B.; Berger, R.; Brust, P.; Pietzsch, H.-J.; Scheunemann, M.; et al. (8 authors)Seifert, S.; Spies, H.; Syhre, R.

European Journal of Nuclear Medicine 24 (1997) 3 pp. 316-319

1996

High-affinity binding of [3H]paroxetine to caudate nucleus and microvessels from porcine brain

Brust, P.; Bergmann, R.; Johannsen, B.

NeuroReport 7 (1996) pp. 1405-1408
DOI: 10.1097/00001756-199605310-00016

Technetium(V) and Rhenium(V) Complexes for 5-HT2A Serotonin Receptor Binding: Structure-Affinity Considerations

Johannsen, B.; Scheunemann, M.; Spies, H.; Brust, P.; Wober, J.; et al. (7 authors)Syhre, R.; Pietzsch, H.-J.

Journal of Nuclear Medicine and Biology 23 (1996) 429-438
DOI: 10.1016/0969-8051(96)00015-7

1995

Specific binding of (3H)imipramine indicates the presence of a specific serotonin transport system on endothelial cells of porcine brain

Brust, P.; Bergmann, R.; Johannsen, B.

Neuroscience Letters 194 (1995) 21-24
DOI: 10.1016/0304-3940(95)11709-6

Evaluation of Radioselenium Labeled Selenomethionine, a Potential Tracer for Brain Protein Synthesis by PET

Bergmann, R.; Brust, P.; Kampf, G.; Coenen, H. H.; Stöcklin, G.

J. Nucl. Med. Biol. 22 (1995) 475-481
DOI: 10.1016/0969-8051(94)00123-2

1994

Characterization of serotonin uptake sites on the blood brain barrier

Brust, P.; Bergmann, R.

Journal of Neurochemistry 63 (1994) (Suppl. 1) S13C

Compartmental analysis of blood brain transfer and protein incorporation of L-[75Se]seleno methionine in rat brain

Bergmann, R.; Brust, P.; Coenen, H. H.; Stöcklin, G.

Journal of Neurochemistry 63 (1994) (Suppl. 1) S78C

Developmental changes of enzymes involved in peptide degradation in isolated rat brain microvessels

Brust, P.; Bech, A.; Kretzschmar, R.; Bergmann, R.

Peptides 15 (1994) 6 pp. 1085-1088
DOI: 10.1016/0196-9781(94)90074-4

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