Publications of Institute of Radiopharmaceutical Cancer Research - Year 2016
19 Publications2016
Targetting microglia activation in schizophrenia by minocycline treatment
Mattei, D.; Ivanov, A.; Ferrai, G.; Jordan, P.; Guneykaya, D.; et al. (16 authors)
- European Neuropsychopharmacology 26(2016), 134
Evaluation of the enantiomer specific biokinetics and radiation doses of [18-F]-fluspidine – a new tracer in clinical translation for imaging of σ1 receptors
Kranz, M.; Sattler, B.; Wüst, N.; Deuther-Conrad, W.; Patt, M.; et al. (13 authors)
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Molecules 21(2016), 1164
DOI: 10.3390/molecules21091164
Synthesis and evaluation of a 18F-labeled 4-phenylpiperidine-4-carbonitrile radioligand for σ1 receptor imaging
Ye, J.; Wang, X.; Deuther-Conrad, W.; Zhang, J.; Li, J.; et al. (10 authors)
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Journal of Labelled Compounds and Radiopharmaceuticals (2016), 332-339
DOI: 10.1002/jlcr.3408
Tos-Nos-Mos: Synthesis of different aryl sulfonate precursors for the radiosynthesis of the alpha7 nicotinic acetylcholine receptor radioligand [18F]NS14490
Rötering, S.; Scheunemann, M.; Günther, R.; Löser, R.; Hiller, A.; et al. (9 authors)
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Applied Radiation and Isotopes 114(2016), 57-62
DOI: 10.1016/j.apradiso.2016.04.028
Radiation dosimetry of the α4β2 nicotinic receptor ligand (+)-[18F]Flubatine, comparing preclinical PET/MRI and PET/CT to first-in-human PET/CT results
Kranz, M.; Sattler, B.; Tiepolt, S.; Wilke, S.; Deuther-Conrad, W.; et al. (15 authors)
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EJNMMI Physics (2016), 3-25
DOI: 10.1186/s40658-016-0160-5
Novel radioligands for cyclic nucleotide phosphodiesterase imaging with positron emission tomography: An update on developments since 2012
Schröder, S.; Wenzel, B.; Deuther-Conrad, W.; Scheunemann, M.; Brust, P.
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Molecules 21(2016)5, 650
DOI: 10.3390/molecules21050650
Varying Chirality Across Nicotinic Acetylcholine Receptor Subtypes: Selective Binding of Quinuclidine Triazole Compounds
Sarasamkan, J.; Scheunemann, M.; Apaijai, N.; Palee, S.; Parichatikanond, W.; et al. (12 authors)
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ACS Medicinal Chemistry Letters 7(2016)10, 890-895
DOI: 10.1021/acsmedchemlett.6b00146
Comparison of in silico, electrochemical, in vitro and in vivo metabolism of a homologous series of (radio)fluorinated sigma1 receptor ligands designed for positron emission tomography
Wiese, C.; Große Maestrup, E.; Galla, F.; Schepmann, D.; Hiller, A.; et al. (13 authors)
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ChemMedChem 11(2016), 2445-2458
DOI: 10.1002/cmdc.201600366
Beta-Amyloid-PET-Bildgebung des Gehirns - DGN-Handlungsempfehlung
Barthel, H.; Meyer, P. T.; Drzezga, A.; Bartenstein, P.; Boecker, H.; et al. (17 authors)
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Nuklearmedizin 55(2016)4, 129-137
DOI: 10.3413/Nukmed-0816-16-04
99mTc-Cyclopentadienyl Tricarbonyl Chelate-Labeled Compounds as Selective Sigma‑2 Receptor Ligands for Tumor Imaging
Li, D.; Chen, Y.; Wang, X.; Deuther-Conrad, W.; Chen, X.; et al. (11 authors)
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Journal of Medicinal Chemistry 59(2016)3, 934-946
DOI: 10.1021/acs.jmedchem.5b01378
LC-MS supported Studies on the in vitro Metabolism of both Enantiomers of Flubatine and the in vivo Metabolism of (+)-[18F]Flubatine – a Positron Emission Tomography Radioligand for Imaging α4β2-Nicotinic Acetylcholine Receptors
Ludwig, F.-A.; Smits, R.; Fischer, S.; Donat, C. K.; Hoepping, A.; et al. (7 authors)
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Molecules 21(2016)9, 1200
DOI: 10.3390/molecules21091200
Thyroid hormone status defines brown adipose tissue activity and browning of white adipose tissues in mice
Weiner, J.; Kranz, M.; Klöting, N.; Kunath, A.; Steinhoff, K.; et al. (20 authors)
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Scientific Reports 6(2016), 38124
DOI: 10.1038/srep38124
Changes in Binding of [123I]CLINDE, a High-Affinity Translocator Protein 18 kDa (TSPO) Selective Radioligand in a Rat Model of Traumatic Brain Injury
Donat, C. K.; Gaber, K.; Meixensberger, J.; Brust, P.; Pinborg, L. H.; et al. (7 authors)
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Neuromolecular Medicine 18(2016)2, 158-169
DOI: 10.1007/s12017-016-8385-y
Development of a High-Affinity PET Radioligand for Imaging Cannabinoid Subtype 2 Receptor
Moldovan, R.-P.; Teodoro, R.; Deuther-Conrad, W.; Kranz, M.; Wang, Y.; et al. (13 authors)
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Journal of Medicinal Chemistry 59(2016)17, 7840-7855
DOI: 10.1021/acs.jmedchem.6b00554
Development of a new radiofluorinated quinoline analog for PET imaging of phosphodiesterase 5 (PDE5) in brain.
Liu, J.; Wenzel, B.; Dukic-Stefanovic, S.; Teodoro, R.; Ludwig, F.-A.; et al. (11 authors)
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Pharmaceuticals 9(2016)2, 22
DOI: 10.3390/ph9020022
ISSN: 1424-8247
PET imaging evaluation of [18F]DBT-10, a novel radioligand specific to α7 nicotinic acetylcholine receptors, in nonhuman primates
Hillmer, A. T.; Zheng, M.-Q.; Li, S.; Scheunemann, M.; Lin, S.-F.; et al. (13 authors)
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European Journal of Nuclear Medicine and Molecular Imaging 43(2016)3, 537-547
Online First (2015) DOI: 10.1007/s00259-015-3209-0
A novel thermoregulatory role for PDE10A in mouse and human adipocytes
Hankir, M.; Kranz, M.; Gnad, T.; Wagner, S.; Deuther-Conrad, W.; et al. (16 authors)
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EMBO Molecular Medicine 8(2016), 796-812
DOI: 10.15252/emmm.201506085
ISSN: 0021-9738
Development of highly potent phosphodiesterase 10A (PDE10A) inhibitors: Synthesis and in vitro evaluation of 1,8-dipyridyl- and 1-pyridinol-substituted imidazo[1,5-a]quinoxalines
Wagner, S.; Scheunemann, M.; Dipper, K.; Egerland, U.; Hoefgen, N.; et al. (7 authors)
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European Journal of Medicinal Chemistry 107(2016), 97-108
DOI: 10.1016/j.ejmech.2015.10.028
On the development of a novel non-peptidic 18F-labeled radiotracer for in vivo imaging of oxytocin receptors with positron emission tomography
Wenzel, B.; Mollitor, J.; Deuther-Conrad, W.; Kranz, M.; Dukic-Stefanovic, S.; et al. (13 authors)
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Journal of Medicinal Chemistry 59(2016)5, 1800-1817
DOI: 10.1021/acs.jmedchem.5b01080
ISSN: 0022-2623