Publications of Institute of Radiopharmaceutical Cancer Research

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284 Publications

2008

Hydrophilic oxybathophenanthroline ligands: Synthesis and copper(II) complexation

Stephan, H.; Juran, S.; Born, K.; Comba, P.; Geipel, G.; Hahn, U.; Werner, N.; Vögtle, F.

New Journal of Chemistry 32(2008), 2016-2022
DOI: 10.1039/b805136d
Cited 8 times in Scopus

An ⁸⁶Y-Labeled Mirror-Image Oligonucleotide: Influence of Y-DOTA Isomers on the Biodistribution in Rats

Schlesinger, J.; Közle, I.; Bergmann, R.; Tamburini, S.; Bolzati, C.; Tisato, F.; Noll, B.; Klussmann, S.; Vonhoff, S.; Wüst, F.; Pietzsch, H.-J.; Steinbach, J.

Bioconjugate Chemistry 19(2008), 928-939
DOI: 10.1021/bc700453h
Cited 31 times in Scopus
Lecture (Conference)
Turku PET Symposium New Targets in Molecular Imaging, 24.-27.05.2008, Turku, Finland
Contribution to proceedings
Turku PET Symposium New Targets in Molecular Imaging, 24.-27.05.2008, Turku, Finland
Abstracts of the XI Turku PET Symposium, Kaarina, Finland: Painola, 978-951-29-3563-5, 11

Synthesis, Copper(II) Complexation, ⁶⁴Cu-Labeling and Bioconjugation of a New Bis(2-pyridylmethyl) Derivative of 1,4,7-Triazacyclononane

Gasser, G.; Tjioe, L.; Graham, B.; Belousoff, M. J.; Juran, S.; Walther, M.; Künstler, J.-U.; Bergmann, R.; Stephan, H.; Spiccia, L.

Bioconjugate Chemistry 19(2008)3, 719-730

Fragmentation Reactions of Singly and Doubly Protonated Thiourea- and Sugar-substituted Cyclams and their Transition Metal Complexes

Felder, T.; Röhrich, A.; Stephan, H.; Schalley, C. A.

Journal of Mass Spectrometry 43(2008), 651-663
DOI: 10.1002/jms.1365
Cited 6 times in Scopus

Labeling of Fatty Acid Ligands with the Strong Electrophilic Metal Fragment [^99mTc(N)(PNP)]²⁺ (PNP = Diphosphane Ligand)

Cazzola, E.; Benini, E.; Pasquali, M.; Mirtschink, P.; Walther, M.; Pietzsch, H.-J.; Uccelli, L.; Boschi, A.; Bolzati, C.; Duatti, A.

Bioconjugate Chemistry 19(2008), 450-460
DOI: 10.1021/bc7002378
Cited 24 times in Scopus

Modified 4+1 Mixed Ligand Technetium Labeled Fatty Acids for Myocardial Imaging: Evaluation of Myocardial Uptake and Biodistribution

Mirtschink, P.; Stehr, S. N.; Pietzsch, H.-J.; Bergmann, R.; Pietzsch, J.; Wunderlich, G.; Heintz, A. C.; Kropp, J.; Spies, H.; Kraus, W.; Deussen, A.; Walther, M.

Bioconjugate Chemistry 19(2008), 97-108
DOI: 10.1021/bc700164c
Cited 22 times in Scopus

2007

Role of P2 purinergic receptors in synaptic transmission under normoxic and ischaemic conditions in the CA1 region of rat hippocampal slices

Coppi, E.; Pugliese, A. M.; Stephan, H.; Müller, C. E.; Pedata, F.

Purinergic Signalling 3(2007), 203-219
DOI: 10.1007/s11302-006-9049-4
Cited 31 times in Scopus

Two mononuclear Tc complexes: [2,2′-(3-phenylpropylimino)- and [2,2′-(propylimino)-bis(ethanethiolato)](4-methoxybenzenethiolato)-oxidotechnetate(V)

Emmerling, F.; Kraus, W.; Noll, B.; Noll, S.; Pietzsch, H.-J.

Acta Crystallographica Section C 63(2007), m579-m582
DOI: 10.1107/S0108270107052870
Cited 1 times in Scopus

(4-Methoxybenzenethiolato-κS)oxido-[2,2-propylimino)-bis(ethanethiolato)- κ³S,N,S]rhenium(V)

Kraus, W.; Emmerling, F.; Noll, B.; Noll, S.; Pietzsch, H.-J.

Acta Crystallographica Section E 63(2007), m3018
DOI: 10.1107/S1600536807056814

Carbohydration of 1,4,8,11-tetraazacyclotetradecane (cyclam): synthesis and binding properties toward concanavalin A

Stephan, H.; Röhrich, A.; Noll, S.; Steinbach, J.; Kirchner, R.; Seidel, J.

Tetrahedron Letters 48(2007), 8834-8838
DOI: 10.1016/j.tetlet.2007.10.071
Cited 10 times in Scopus

Myocardial uptake and biodistribution of newly designed technetium-labelled fatty acid analogues

Heintz, A. C.; Jung, C. M.; Stehr, S. N.; Mirtschink, P.; Walther, M.; Pietzsch, J.; Bergmann, R.; Pietzsch, H.-J.; Spies, H.; Wunderlich, G.; Kropp, J.; Deussen, A.

Nuclear Medicine Communications 28(2007)8, 637-647
ISSN: 0143-3636

Cluster Core Controlled Reactions of Substitution of Terminal Bromide Ligands by Triphenylphosphine in Octahedral Rhenium Chalcobromide Complexes

Shestopalov, M. A.; Brylev, K. A.; Kozlova, S. G.; Fedorov, V. E.; Spies, H.; Pietzsch, H.-J.; Stephan, H.; Geipel, G.; Bernhard, G.

Journal of the American Chemical Society 129(2007), 3714-3721

Very stable ¹⁸⁸Re-S4 chelates for labelling biomolecules, prepared with highly concentrated perrhenate eluates

Seifert, S.; Jentschel, C.; Bergmann, R.; Pietzsch, H.-J.; Wunderlich, G.; Kotzerke, J.; Steinbach, J.

Nuklearmedizin 5(2007), 181-184
ISSN: 0029-5566

Organometallic ^99mTc(III) 4+1 Bombesin(7-14) Conjugates: Synthesis, Radiolabeling and In Vitro/In Vivo Studies

Künstler, J.-U.; Veerendra, B.; Figueroa, S. D.; Sieckmann, G. L.; Rold, T. L.; Hoffman, T. J.; Smith, C. J.; Pietzsch, H.-J.

Bioconjugate Chemistry 18(2007), 1651-1661

Extraction of radio-labelled xanthine derivatives by artificial receptors deep insight into the association behaviour

Bomkamp, M.; Siering, C.; Landrock, K.; Stephan, H.; Fröhlich, R.; Waldvogel, S. R.

Chemistry - A European Journal 13(2007), 3724-3732
DOI: 10.1002/chem.200601231
Cited 30 times in Scopus

Comparison of in vitro and in vivo properties of ^99mTc-cRGD peptides labelled using different novel Tc-cores

Decristoforo, C.; Santos, I.; Pietzsch, H.-J.; Duatti, A.; Smith, C. J.; Rey, A.; Alberto, R.; von Guggenberg, E.; Haubner, R.

Quarterly Journal of Nuclear Medicine and Molecular Imaging 51(2007), 33-41

Synthesis and biological evaluation of a new type of ^99mTechnetium-labeled fatty acid for myocardial metabolism imaging

Walther, M.; Jung, C.; Bergmann, R.; Pietzsch, J.; Rode, K.; Fahmy, K.; Mirtschink, P.; Stehr, S.; Heintz, A.; Wunderlich, G.; Kraus, W.; Pietzsch, H.-J.; Kropp, J.; Deussen, A.; Spies, H.

Bioconjugate Chemistry 18(2007), 216-230
ISSN: 10.1021/bc0601222

2006

Polyoxometalates a new class of potent ecto-nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitors

Müller, C. E.; Iqbal, J.; Baqi, Y.; Zimmermann, H.; Röllich, A.; Stephan, H.

Bioorganic & Medicinal Chemistry Letters 16(2006), 5943-5947
DOI: 10.1016/j.bmcl.2006.09.003
Cited 160 times in Scopus

Preparation and Biological Characterization of Isomeric ¹⁸⁸Re(V) Oxocomplexes with Tetradentate S₄ Ligands Derived from DMSA for Labeling of Biomolecules

Seifert, S.; Heinrich, T.; Jentschel, C.; Smuda, C.; Bergmann, R.; Pietzsch, H.-J.

Bioconjugate Chemistry 17(2006), 1601-1606
DOI: 10.1021/bc0602331
Cited 9 times in Scopus

Bromo(tricarbonyl) (15-{[2-(methylthio-S)ethylthio-S} pentadecanoic acid)rhenium(l)

Kraus, W.; Walther, M.; Jung, C. M.; Emmerling, F.; Pietzsch, H.-J.

Acta Crystallographica Section E 62(2006), m1660-m1662
DOI: 10.1107/S1600536806024081
Cited 1 times in Scopus

Tetrabutylammonium bis(2-amidobenzenethiolato-k²S,N)oxorhenate(V)

Gniazdowska, E.; Kraus, W.; Emmerling, F.; Spies, H.; Stephan, H.

Acta Crystallographica Section E 62(2006), m1197-m1199
DOI: 10.1107/S160053680601511X

Two- and Threefold Intramolecular Bridging p-tert- Butylcalix[8]arene Triphosphates Synthesis, Structure and Stereochemistry

Gloede, J.; Ozegowski, S.; Keitel, I.; Gruner, M.; Costisella, B.; Pritzkow, W.; Stephan, H.; Bartoschek, M.

Zeitschrift für Anorganische und Allgemeine Chemie (2006)632, 123-132

Chitosan-encapsulated Keggin anion [Ti₂W₁₀PO₄₀]^7-: Synthesis, characterization and cellular uptake studies

Meißner, T.; Bergmann, R.; Oswald, J.; Rode, K.; Richter, W.; Zänker, H.; Kraus, W.; Emmerling, F.; Reck, G.; Stephan, H.

Transition Metal Chemistry 31(2006)5, 603-610
DOI: 10.1007/s11243-006-0035-z
ISSN: 0340-4285
Cited 27 times in Scopus

Novel and Efficient Preparation of Precursor [¹⁸⁸Re(OH₂)₃(CO)₃]⁺ for the Labeling of Biomolecules

Park, S. H.; Seifert, S.; Pietzsch, H.-J.

Bioconjugate Chemistry 17(2006), 223-225

A new molecular mechanics force field for the design of oxotechnetium(V) and oxorhenium(V) radiopharmaceuticals

Comba, P.; Daubinet, A.; Martin, B.; Pietzsch, H.-J.; Stephan, H.

Journal of Organometallic Chemistry 691(2006)11, 2495-2502

Octahedral rhenium cluster complexes with inner organic ligands: synthesis, structure and properties of [Re6Q8(3,5-Me2PzH)6]Br2·2(3,5-Me2PzH) (Q = S, Se)

Mironov, Y.; Bryleva, K.; Shestopalova, M.; Yarovoia, S.; Fedorova, V.; Spies, H.; Pietzsch, H.-J.; Stephan, H.; Geipel, G.; Bernhard, G.; Kraus, W.

Inorganica Chimica Acta (2006)359, 1129-1134

¹⁸⁸Re(III)-EDTA - a Multipurpose Starting Material for the Preparation of Relevant ¹⁸⁸Re Complexes under Mild Conditions

Seifert, S.; Pietzsch, H.-J.

Applied Radiation and Isotopes 64(2006), 223-227

2005

[Re6Q7O(3,5-Me2PzH)6]Br2·3,5-Me2PzH (Q = S, Se) new octahedral rhenium cluster complexes with organic ligands: original synthetic approach and unexpected ligand exchange in cluster core

Mironov, Y. V.; Shestopalov, M. A.; Brylev, K. A.; Yarovoi, A. S.; Romanenko, G. V.; Fedorov, V. E.; Spies, H.; Pietzsch, H.-J.; Stephan, H.; Geipel, G.; Bernhard, G.; Kraus, W.

European Journal of Inorganic Chemistry (2005), 657-661

{2-Carboxy-2-{bis[(2-thiolato-_S)ethyl]amino-_N}ethanthiolato-_S} (triphenylphosphin-_P)rhenium(III)

Schiller, E.; Kraus, W.; Reck, G.; Spies, H.; Pietzsch, H.-J.

Acta Crystallographica Section E 61(2005), M1373-M1375
ISSN: 1600-5368

A novel rhenium chelate system derived from dimercaptosuccinic acid for the selective labeling of biomolecules

Heinrich, T.; Kraus, W.; Pietzsch, H.-J.; Smuda, C.; Spies, H.

Inorganic Chemistry 44(2005)26, 9930-9937

Disruption of unprecedented B-H...M agostic interactions: An alternative approach for labeling bioactive molecules

Garcia, R.; Paulo, A.; Domingos, A.; Santos, I.; Pietzsch, H.-J.

Synthesis and Reactivity in Inorganic, Metal-Organic and Nano-Metal Chemistry 35(2005)1, 35-42

Synthesis and Binding Properties of Dendritic Oxybathophenanthroline Ligands towards Copper(II)

Stephan, H.; Geipel, G.; Bernhard, G.; Comba, P.; Rajaraman, G.; Hahn, U.; Vögtle, F.

European Journal of Inorganic Chemistry 22(2005), 4501-4508
DOI: 10.1002/ejic.200500176
Cited 9 times in Scopus

K₆H₂[TiW₁₁CoO₄₀]×13H₂O, with a monotitanoundecatungstocobaltate(II) anion

Kraus, W.; Stephan, H.; Röllich, A.; Matéjka, Z.; Reck, G.

Acta Crystallographica Section E 61(2005), i35-i37
ISSN: 1600-5368

Mixed-Ligand Rhenium-188 Complexes with Tetradentate/Monodentate NS3/P (4+1) Coordination: Relation of structure with antioxidation stability

Schiller, E.; Seifert, S.; Tisato, F.; Refosco, F.; Bolzati, C.; Kraus, W.; Spies, H.; Pietzsch, H.-J.

Bioconjugate Chemistry 16(2005), 634-643

[Re₆Q₇O(3,5-Me₂PzH)₆]Br₂*3,5-Me₂PzH (Q = S, Se) - new octahedral rhenium cluster complexes with organic ligands: original synthetic approach and unexpected ligand exchange in cluster core

Mironov, Y. V.; Shestopalov, M. A.; Brylev, K. A.; Yarovoi, S. S.; Romanenko, G.; Fedorov, V. E.; Spies, H.; Pietzsch, H.-J.; Stephan, H.; Geipel, G.; Bernhard, G.; Kraus, W.

European Journal of Inorganic Chemistry (2005)4, 657-661

Pegylation of 1,4,8,11-Tetraazacyclotetradecane (Cyclam) and its Copper(II) Complexation

Stephan, H.; Geipel, G.; Bernhard, G.; Appelhans, D.; Tabuani, D.; Komber, H.; Voit, B.

Tetrahedron Letters 46(2005), 3209-3212

2004

The crucial role of the diphosphine heteroatom X in the stereochemistry and stabilization of the substitution-inert [M(N)(PXP)]²⁺ metal fragments (M = Tc, Re; PXP = diphosphine ligand)

Tisato, F.; Refosco, F.; Porchia, M.; Bolzati, C.; Bandoli, G.; Dolmella, A.; Duatti, A.; Boschi, A.; Jung, C. M.; Pietzsch, H.-J.; Kraus, W.

Inorganic Chemistry 43(2004), 8617-8625

Cyclopentadienyl tricarbonyl complexes of ^99mTC for the in vivo imaging of the serotonin 5-HT_1A receptor in the brain

Saidi, M.; Kretzschmar, M.; Seifert, S.; Bergmann, R.; Pietzsch, H.-J.

Invited lecture (Conferences)
2. International Symposium on Bioorganometallic Chemistry (ISBOMC04), 14.-19.07.2004, Zürich, Swizerland
Journal of Organometallic Chemistry 689(2004)25, 4739-4744
DOI: 10.1016/j.jorganchem.2004.09.004
Cited 36 times in Scopus

Novel Procedures for Preparing ^99mTc(III) Complexes with Tetradentate/Monodentate Coordination of Varying Lipophilicity and Adaptation to ¹⁸⁸Re Analogues

Seifert, S.; Künstler, J.-U.; Pietzsch, H.-J.; Pawelke, B.; Bergmann, R.; Spies, H.

Bioconjugate Chemistry 15(2004)4, 856-863
DOI: 10.1021/bc0300798
Cited 59 times in Scopus

Synthesis, Characterization, and Biological Evaluation of Neutral Nitrido Technetium(V) Mixed Ligand Complexes Containing Dithiolates and Aminodiphosphines. A Novel System for Linking Technetium to Biomolecules

Bolzati, C.; Benini, E.; Cazzola, E.; Jung, C.; Tisato, F.; Refosco, F.; Pietzsch, H.-J.; Spies, H.; Uccelli, L.; Duatti, A.

Bioconjugate Chemistry 15(2004), 628-637

2003

In vivo Measurement of the Serotonin Transporter with (S)-([¹⁸F]fluoromenthyl)-(+)-McN5652

Brust, P.; Hinz, R.; Kuwabara, H.; Hesse, S.; Zessin, J.; Pawelke, B.; Stephan, H.; Bergmann, R.; Steinbach, J.; Sabri, O.

Neuropsychopharmacology (2003) 28, 2010-2019

Alkyl-Substituted 2,6-Dioxadiazolylpyridines as Selective Extractants for Trivalent Actinides

Weigl, M.; Müllich, U.; Geist, A.; Gompper, K.; Zevaco, T.; Stephan, H.

Journal of Radioanalytical and Nuclear Chemistry, 256/3 (2003) 403-412

Where the anion extraction is going?

Gloe, K.; Stephan, H.; Grotjahn, M.

Chem. Eng. Technol. 26 (2003) 1107-1117

Towards promising oxoanion extractants: azacages and open-chain counterparts

Farrell, D.; Gloe, K.; Gloe, K.; Goretzki, G.; Mckee, V.; Nelson, J.; Nieuwenhuyzen, M.; Pál, I.; Stephan, H.; Town, R. M.; Wichmann, K.

J. Chem. Soc., Dalton Trans. (2003) 1961-1968
Lecture (Conference)
Dalton Discussion 5 "Ligand Design for Functional Complexes", Noordwijkerhout, The Netherlands, 10.-12.04.2003

A new Cryptophane Receptor Featuring Three endo-Carboxylic Acid Groups: Synthesis, Host Behavior and Structural Study

Roesky, C. E. O.; Weber, E.; Rambusch, T.; Stephan, H.; Gloe, K.; Czugler, M.

Chemistry, A European Journal 9/5 (2003) 1104-1112

Aqueous synthesis of derivatized cyclopentadienyl complexes of technetium and rhenium directed towards radiopharmaceutical application

Bernard, J.; Ortner, K.; Spingler, B.; Pietzsch, H.-J.; Alberto, R.

Inorganic Chemistry 42 (2003) 1014-1022

Synthesis, characterization and biological evaluation of technetium(III) complexes with tridendate/bidendate S,E,S/P,S coordination (E = O, N(CH₃), S): A novel approach to robust technetium chelates suitable for linking the metal to biomolecules

Pietzsch, H.-J.; Seifert, S.; Syhre, R.; Tisato, F.; Refosco, F.; Leibnitz, P.; Spies, H.

Bioconjugate Chemistry 14 (2003) 136-143

2002

Quo vadis Anionenextraktion?

Gloe, K.; Stephan, H.; Grotjahn, M.

Chemie Ingenieur Technik 74 (2002) 767-777

A novel technetium-99m radioligand for the 5-HT_1A receptor derived from desmethyl-WAY-100635 (DWAY)

Heimbold, I.; Drews, A.; Syhre, R.; Kretzschmar, M.; Pietzsch, H.-J.; Johannsen, B.

European Journal of Nuclear Medicine 29 (2002) 82-87

Syntheses and first crystal structures of rhenium complexes derived from omega-functionalized fatty acids as model compounds of technetium tracers for myocardial metabolism imaging

Jung, C. M.; Kraus, W.; Leibnitz, P.; Pietzsch, H.-J.; Kropp, J.; Spies, H.

European Journal of Inorganic Chemistry (2002) 1219-1225

Synthesis and biological evaluation of technetium(III) mixed-ligand complexes with high affinity for the cerebral 5-HT_1A receptor and the alpha1-adrenergic receptor

Drews, A.; Pietzsch, H.-J.; Syhre, R.; Seifert, S.; Varnäs, K.; Hall, H.; Halldin, C.; Kraus, W.; Karlsson, P.; Johnsson, C.; Spies, H.; Johannsen, B.

Nuclear Medicine and Biology 29 (2002) 389-398

Development of technetium-99m-based CNS receptor ligands: have there been any advances?

Johannsen, B.; Pietzsch, H.-J.

Eur. J. Nucl. Med. 29 (2002) 263-275

Synthesis , biological and autoradiographic evaluation of a novel Tc-99m radioligand derived from WAY 100635 with high-affinity for the 5-HT_1A receptor and the alpha1-adrenergic receptor

Heimbold, I.; Drews, A.; Kretzschmar, M.; Varnäs, K.; Hall, H.; Halldin, C.; Syhre, R.; Kraus, W.; Pietzsch, H.-J.; Seifert, S.; Brust, P.; Johannsen, B.

Nuclear Medicine and Biology 29 (2002) 375-387

2001

Synthesis and properties of triethyl(triphenyl)siloxyalkyl(aryl)thiolato(3-thiapentane-1,5-dithialato)oxorhenium(V)- potential brain seeking agents

Abedin, M. Z.; Spies, H.; Pietzsch, H.-J.; Zablotskaya, A.

Bangladesh Journal of Nuclear Medicine (2001) 1-6.

Synthesis and host-guest properties of multi-crown-dendrimers towards sodium pertechnetate and mercury(II) chloride

Stephan, H.; Spies, H.; Johannsen, B.; Gloe, K.; Gorka, M.; Vögtle, F.

Eur. J. Inorg. Chem. (2001) 2957-2963

Reactivity of Technetium(I) Thioether Carbonyl Complexes towards Histidine - An EXAFS Study in Solution

Seifert, S.; Künstler, J.-U.; Gupta, A.; Funke, H.; Reich, T.; Pietzsch, H.-J.; Alberto, R.; Johannsen, B.

Inorganica Chimica Acta 322 (2001) 79-86

Mixed-ligand technetium(III) complexes with tetra-dendate/monodendate NS₃/isocyanide coordination: A new nonpolar Technetium chelate system for the design of neutral and lipophilic complexes stable in vivo

Pietzsch, H.-J.; Gupta, A.; Syhre, R.; Leibnitz, P.; Spies, H.

Bioconjugate Chem. Vol.12 Nr. 4 (2001) 538-544

Synthesis and characterization of novel trigonal-bipyramidal technetium(III) mixed-ligand complexes with SES/S/P coordination (E = O, N(CH₃), S)

Pietzsch, H.-J.; Tisato, F.; Refosco, F.; Leibnitz, P.; Drews, A.; Seifert, S.; Spies, H.

Inorg. Chem. 40 (2001), 40, 59-64

2000

pH-controlled inclusion and release of oxyanions by denrimers bearing methyl orange moieties

Stephan, H.; Spies, H.; Johannsen, B.; Kaufmann, C.; Vögtle, F.

Organic Letters 2 (15) (2000) 2343-2346

Glutathione interaction with SNS/S mixed ligand complexes of oxorhenium(V): Kinetic aspects and characterization of the products

Nock, B.; Maina, T.; Tsortos, A.; Pelecanou, M.; Raptopoulou, C. P.; Papadopoulos, M.; Pietzsch, H.-J.; Stassinopoulou, C.; Terzis, A.; Spies, H.; Nounesis, G.; Chiotellis, E.

Inorganic Chemistry 39 (2000) 4433-4441

EXAFS Analyses of Technetium(I) Carbonyl Complexes - Stability Studies in Solutions

Seifert, S.; Kuenstler, J.-U.; Gupta, A.; Funke, H.; Reich, T.; Hennig, C.; Rossberg, A.; Pietzsch, H.-J.; Alberto, R.; Johannsen, B.

Radiochim. Acta 88 (2000) 239-245

Chemical and biological characterization of technetium(I) and rhenium(I) tricarbonyl complexes with dithioether ligands serving as linkers for coupling the Tc(CO)₃ and Re(CO)₃ moieties to biologically active molecules

Pietzsch, H.-J.; Gupta, A.; Reisgys, M.; Drews, A.; Seifert, S.; Syhre, R.; Spies, H.; Alberto, R.; Abram, U.; Schubiger, P. A.

Bioconjugate Chem. 11 (2000) 414-424

Oxorhenium mixed-ligand complexes with the 2,6-dimercaptomethylpyridine ligand. Crystal structure of [2,6-dimercaptomethylpyridinato][p-methoxybenzenethiolato]oxorhenium(V)

Nock, B.; Pietzsch, H.-J.; Tisato, F.; Maina, T.; Leibnitz, P.; Spies, H.; Chiotellis, E.

Inorg. Chim. Acta 304 (2000) 26-32

Stability Studies on ^99mTechnetium(III) Complexes with Tridentate/Monodentate Thiol Ligands and Phosphine ("3+1+1" Complexes)

Seifert, S.; Drews, A.; Gupta, A.; Pietzsch, H.-J.; Spies, H.; Johannsen, B.

Appl. Radiat. Isot. 53 (2000) 431-438

Assessment of the in vitro and in vivo properties of a ^99mTc-labeled inhibitor of the multidrug resistant gene product P-glycoprotein.

Bergmann, R.; Brust, P.; Scheunemann, M.; Pietzsch, H.-J.; Seifert, S.; Roux, F.; Johannsen, B.

Nucl. Med. Biol. 27 (2000) 135-141

1999

Study on the formation of mixed ligand oxorhenium and oxotechnetium complexes (SNS/S combination)

Papadopoulos, M.; Pirmettis, I.; Tsoukalas, C.; Nock, B.; Maina, T.; Raptopoulou, C. P.; Terzis, A.; Pietzsch, H.-J.; Friebe, M.; Spies, H.; Johannsen, B.; Chiotellis, E.

Inorg. Chim. Acta 295 (1999) 1-8

Lipophilic urea-functionalized dendrimers as efficient carriers for oxyanions

Stephan, H.; Spies, H.; Johannsen, B.; Klein, L.; Vögtle, F.

Chem. Commun., 1999, 1875-1876

First Application of fac-[^99mTc(OH₂)₃(CO)₃]⁺ in Bioorganometallic Chemistry: Design, Structure, and in Vitro Affinity of a 5-HT_1A Receptor Ligand Labeled with ^99mTc

Alberto, R.; Schibli, R.; Schubiger, P. A.; Abram, U.; Pietzsch, H.-J.; Johannsen, B.

J. Am. Chem. Soc. 121, 25, 1999, 6076-6077

Efficient phase transfer of pertechnetate with bicyclic guanidinium compounds

Stephan, H.; Berger, R.; Spies, H.; Johannsen, B.; Schmidtchen, F.-P.

Journal of Radioanalytical and Nuclear Chemistry 242 (2) (1999) 399-403

Synthesis and Autoradiographical Evaluation of a Novel High-Affinity Tc-99m Ligand for the 5-HT_2A Receptor

Pietzsch, H.-J.; Scheunemann, M.; Kretzschmar, M.; Elz, S.; Pertz, H. H.; Seifert, S.; Brust, P.; Spies, H.; Syhre, R.; Johannsen, B.

Nuclear Medicine and Biology, 26 (1999) 865-875

1998

No Carrier Added Preparations of '3+1' Mixed-Ligand ^99mTc Complexes

Seifert, S.; Pietzsch, H.-J.; Scheunemann, M.; Spies, H.; Syhre, R.; Johannsen, B.

Appl. Radiat. Isot. Vol. 49, Nos 1-2, pp. 5-11, 1998
DOI: 10.1016/S0969-8043(97)00221-2
Cited 29 times in Scopus

1997

Technetium and rhenium complexes with thioether ligands. VI. Synthesis and structural characterization of mixed-ligand oxorhenium(V) complexes containing bidentate dithioethers and monothiolato ligands.

Reisgys, M.; Spies, H.; Johannsen, B.; Leibnitz, P.; Pietzsch, H.-J.

Chem. Ber. 130 (1997) 1343-1347

Synthesis of Rhenium(I) and Technetium(I) Carbonyl/Dithioether Ligand Complexes Bearing 3,17-BETA-Estradiol

Reisgys, M.; Wüst, F.; Alberto, R.; Schibli, R.; Schubiger, P. A.; Pietzsch, H.-J.; Spies, H.; Johannsen, B.

Bioorganic and Medicinal Chemistry Letters, Vol. 7, No. 17, pp 2243-2246, 1997
DOI: 10.1016/S0960-894X(97)00396-X
Cited 28 times in Scopus

Synthesis and Structural Characterization of Neutral Oxorhenium(V) Complexes with Tridentate Dithioethers

Pietzsch, H.-J.; Reisgys, M.; Spies, H.; Leibnitz, P.; Johannsen, B.

Chemische Berichte 130 (1997) pp. 357-361

Structural modification of receptor binding 99m-Tc complexes in order to improve brain uptake

Johannsen, B.; Berger, R.; Brust, P.; Pietzsch, H.-J.; Scheunemann, M.; Seifert, S.; Spies, H.; Syhre, R.

European Journal of Nuclear Medicine 24 (1997) 3 pp. 316-319

Technetium and Rhenium Complexes with Thioether Ligands, 5 Synthesis and Structural Characterization of Neutral Oxorhenium (V) Complexes with Tridentate Dithioethers

Pietzsch, H.-J.; Reisgys, M.; Spies, H.; Leibnitz, P.; Johannsen, B.

Chemische Berichte, Recueil 1997, 130, 357-361

1996

Technetium(V) and Rhenium(V) Complexes for 5-HT2A Serotonin Receptor Binding: Structure-Affinity Considerations

Johannsen, B.; Scheunemann, M.; Spies, H.; Brust, P.; Wober, J.; Syhre, R.; Pietzsch, H.-J.

Journal of Nuclear Medicine and Biology 23 (1996) 429-438
DOI: 10.1016/0969-8051(96)00015-7
Cited 61 times in Scopus

1995

Synthesis and reactions of trigonal-bipyramidal rhenium and technetium complexes with a tripodal, tetradentate NS3 ligand*

Spies, H.; Glaser, M.; Pietzsch, H.-J.; Hahn, F. E.; Lügger, T.

Inorganica Chimica Acta 240 (1995) pp. 465-478

Neutral Oxorhenium(V) Complexes with Tridentate Dithiolates and Monodentate Alkane- or Arene-thiolate Coligands

Spies, H.; Fietz, T.; Pietzsch, H.-J.; Johannsen, B.; Leibnitz, P.; Reck, G.; Scheller, D.; Klostermann, K.

Journal of the Chemical Society Dalton Transactions (1995) 13 pp. 2277-2280
DOI: 10.1039/dt9950002277
Cited 59 times in Scopus

Technetium- and Rhenium Complexes with Thioether Ligands-IV. Synthesis and Structural Characterization of Binuclear Oxorhenium (V) Complexes with Bidentate Thioether Coordination

Pietzsch, H.-J.; Spies, H.; Leibnitz, P.; Reck, G.

Polyhedron 14 (1995) 13-14 pp.1849-1853
DOI: 10.1016/0277-5387(94)00470-Y
Cited 22 times in Scopus

Synthesis and molecular structure of chlore(3-thiapentane-1.5-dithiolato)oxorhenium(V)

Fietz, T.; Spies, H.; Pietzsch, H.-J.; Leibnitz, P.

Inorganica Chimica Acta 231 (1995) pp. 233-236
DOI: 10.1016/0020-1693(94)04351-U
Cited 61 times in Scopus

1994

Trigonal-bipyramidale Technetium- und Rhenium-Komplexe mit vierzähnigen tripodalen NS₃-Liganden

Spies, H.; Glaser, M.; Pietzsch, H.-J.; Hahn, F. E.; Kintzel, O.; Lügger, T.

Angewandte Chemie 106 (1994) 13 pp. 1416-1419

1993

Technetium Complexes with Thioether Ligands

Pietzsch, H.-J.; Spies, H.; Leibnitz, P.; Reck, G.; Johannsen, B.

Radiochimica Acta 63 (1993) pp. 163-166
DOI: 10.1524/ract.1993.63.special-issue.163

Technetium Complexes with Thioether Ligands - III. Synthesis and Structural Characterization of Cationic Nitridotechnetium(V) Complexes with Thiacrown ethers