Publications of Institute of Radiopharmaceutical Cancer Research

407 Publications

2024

Impact of Viscosity on Human Hepatoma Spheroids in Soft Core-Shell Microcapsules

Peng, X.; Janićijević, Ž.; Lemm, S.; Hauser, S.; Knobel, M.; Pietzsch, J.; Bachmann, M.; Baraban, L.

Production of medical radionuclides in the Center for Radiopharmaceutical Tumor Research – a status report

Kreller, M.; Walther, M.; Brühlmann, S. A.; Knieß, T.; Kopka, K.

Involved research facilities

  • PET-Center
  • ZRT

Preclinical evaluation of an ¹⁸F-labeled Nε-acryloyllysine piperazide for covalent targeting of transglutaminase 2

Wodtke, R.; Laube, M.; Hauser, S.; Meister, S.; Ludwig, F.-A.; Fischer, S.; Kopka, K.; Pietzsch, J.; Löser, R.

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  • PET-Center

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Improving susceptibility of neuroendocrine tumors to radionuclide therapies: personalized approaches towards complementary treatments

Richter, S.; Steenblock, C.; Lemm, S.; Ziegler, C. G.; Bechmann, N.; Nölting, S.; Pietzsch, J.; Ullrich, M.

Shell engineering in soft alginate-based capsules for culturing liver spheroids

Peng, X.; Janićijević, Ž.; Lemm, S.; Laube, M.; Pietzsch, J.; Bachmann, M.; Baraban, L.

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2023

Molecular imaging of bacterial outer membrane vesicles based on bacterial surface display

Szöllősi, D.; Hajdrik, P.; Tordai, H.; Horváth, I.; Veres, D. S.; Gillich, B.; Das Shailaja, K.; Smeller, L.; Bergmann, R.; Bachmann, M.; Mihály, J.; Gaál, A.; Jezsó, B.; Barátki, B.; Kövesdi, D.; Bősze, S.; Szabó, I.; Felföldi, T.; Oszwald, E.; Padmanabhan, P.; Zoltán Gulyás, B.; Hamdani, N.; Máthé, D.; Varga, Z.; Szigeti, K.

Radiosynthesis and biological evaluation of [¹⁸F]AG-120 for PET imaging of the mutant isocitrate dehydrogenase 1 in gliomas

Lai, T. H.; Wenzel, B.; Dukic-Stefanovic, S.; Teodoro, R.; Arnaud, L.; Maisonial-Besset, A.; Weber, V.; Moldovan, R.-P.; Meister, S.; Pietzsch, J.; Kopka, K.; Juratli, T. A.; Deuther-Conrad, W.; Toussaint, M.

Lysyl oxidases as targets for cancer therapy and diagnostic imaging

Löser, R.; Kuchar, M.; Wodtke, R.; Neuber, C.; Belter, B.; Kopka, K.; Santhanam, L.; Pietzsch, J.

A novel ACE2 decoy for both neutralization of SARS-CoV-2 variants and killing of infected cells

Kegler, A.; Drewitz, L.; Arndt, C.; Daglar, C.; Rodrigues Loureiro, L. R.; Mitwasi, N.; Neuber, C.; González Soto, K. E.; Bartsch, T.; Baraban, L.; Ziehr, H.; Heine, M.; Nieter, A.; Moreira-Soto, A.; Kühne, A.; Drexler, J. F.; Seliger, B.; Laube, M.; Máthé, D.; Pályi, B.; Hajdrik, P.; Forgách, L.; Kis, Z.; Szigeti, K.; Bergmann, R.; Feldmann, A.; Bachmann, M.

Involved research facilities

  • ZRT

Synthesis and In Vitro Biological Evaluation of p-Carborane-based Di-tert-butylphenol Analogs

Braun, S.; Jelača, S.; Laube, M.; George, S.; Hofmann, B.; Lönnecke, P.; Steinhilber, D.; Pietzsch, J.; Mijatović, S.; Maksimović-Ivanić, D.; Hey-Hawkins, E.

FLT3-directed UniCAR T-cell therapy of Acute Myeloid Leukaemia

Peschke, J.; Bergmann, R.; Mehnert, M.; González Soto, K. E.; Rodrigues Loureiro, L. R.; Mitwasi, N.; Kegler, A.; Altmann, H.; Wobus, M.; Máthé, D.; Szigeti, K.; Feldmann, A.; Bornhäuser, M.; Bachmann, M.; Fasslrinner, F.; Arndt, C.

Preclinical Characterization of the 177Lu-Labeled Prostate Stem Cell Antigen (PSCA)-Specific Monoclonal Antibody 7F5

Striese, F.; Neuber, C.; Gräßel, S.; Arndt, C.; Ullrich, M.; Steinbach, J.; Pietzsch, J.; Bergmann, R.; Pietzsch, H.-J.; Sihver, W.; Frenz, M.; Feldmann, A.; Bachmann, M.

Involved research facilities

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Carborane-based Tebufelone Analogs and their Biological Evaluation In Vitro

Braun, S.; Paskas, S.; Laube, M.; George, S.; Hofmann, B.; Lönnecke, P.; Steinhilber, D.; Pietzsch, J.; Mijatović, S.; Maksimović-Ivanić, D.; Hey-Hawkins, E.

Specific and safe targeting of glioblastoma using switchable and logic-gated RevCAR T cells

Abdelfatah Saleh Hassan, H. A.; Mitwasi, N.; Ullrich, M.; Kubeil, M.; Toussaint, M.; Deuther-Conrad, W.; Neuber, C.; Arndt, C.; Rodrigues Loureiro, L. R.; Kegler, A.; González Soto, K. E.; Belter, B.; Rössig, C.; Pietzsch, J.; Frenz, M.; Bachmann, M.; Feldmann, A.

Involved research facilities

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Isonimesulide and its carborane analogues as isoform-selective COX inhibitors and antitumor agents

Useini, L.; Komazec, T.; Laube, M.; Lönnecke, P.; Schädlich, J.; Mijatović, S.; Maksimović-Ivanić, D.; Pietzsch, J.; Hey-Hawkins, E.

Comparative saturation binding analysis of ⁶⁴Cu-labeled somatostatin analogs using cell homogenates and intact cells

Ullrich, M.; Brandt, F.; Löser, R.; Pietzsch, J.; Wodtke, R.

Involved research facilities

  • ZRT

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Metastatic pheochromocytoma and paraganglioma: somatostatin receptor 2 expression, genetics and therapeutic responses

Fischer, A.; Kloos, S.; Maccio, U.; Friemel, J.; Remde, H.; Fassnacht, M.; Pamporaki, C.; Eisenhofer, G.; Timmers, H. J. L. M.; Robledo, M.; Fliedner, S. M. J.; Wang, K.; Maurer, J.; Reul, A.; Zitzmann, K.; Bechmann, N.; Žygienė, G.; Richter, S.; Hantel, C.; Vetter, D.; Lehmann, K.; Mohr, H.; Pellegata, N. S.; Ullrich, M.; Pietzsch, J.; Ziegler, C. G.; Bornstein, S. R.; Kroiss, M.; Reincke, M.; Pacak, K.; Grossman, A. B.; Beuschlein, F.; Nölting, S.

Impedimetric Nanobiosensor for the Detection of SARS-CoV-2 Antigens and Antibodies

Sandoval Bojorquez, D. I.; Janićijević, Ž.; Palestina Romero, B.; Oliveros Mata, E. S.; Laube, M.; Feldmann, A.; Kegler, A.; Drewitz, L.; Fowley, C.; Pietzsch, J.; Faßbender, J.; Tonn, T.; Bachmann, M.; Baraban, L.

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Synthesis of [18F]FMISO, a hypoxia-specific imaging probe for PET, an overview from a radiochemist’s perspective

Knieß, T.; Zessin, J.; Mäding, P.; Kuchar, M.; Kiß, O.; Kopka, K.

Involved research facilities

  • PET-Center
  • ZRT

Cyclotron-based Production of 67Cu for Radionuclide Theranostics Via the 70Zn(p,α)67Cu Reaction

Brühlmann, S. A.; Walther, M.; Kreller, M.; Reissig, F.; Pietzsch, H.-J.; Knieß, T.; Kopka, K.

Solid-Phase Parallel Synthesis of Dual Histone Deacetylase-Cyclooxygenase Inhibitors

Bachmann, L. M.; Hanl, M.; Feller, F.; Sinatra, L.; Schöler, A.; Pietzsch, J.; Laube, M.; Hansen, F. K.

Carborane Analogues of Fenoprofen Exhibit Improved Antitumor Activity

Useini, L.; Mojić, M.; Laube, M.; Lönnecke, P.; Mijatović, S. S.; Maksimović-Ivanić, D.; Pietzsch, J.; Hey-Hawkins, E.

The Impact of Nε-Acryloyllysine Piperazides on the Conformational Dynamics of Transglutaminase 2

Heerwig, A.; Kick, A.; Sommerfeld, P.; Eimermacher, S.; Hartung, F.; Laube, M.; Fischer, D.; Pietzsch, H.-J.; Pietzsch, J.; Löser, R.; Mertig, M.; Pietsch, M.; Wodtke, R.

Involved research facilities

  • ZRT

In vitro Cytostatic Effect on Tumor Cells by Carborane-based Dual Cyclooxygenase-2 and 5-Lipoxygenase Inhibitors

Braun, S.; Paskas, S.; Laube, M.; George, S.; Hofmann, B.; Lönnecke, P.; Steinhilber, D.; Pietzsch, J.; Mijatović, S. S.; Maksimović-Ivanić, D.; Hey-Hawkins, E.

Microdialysis reveals anti-inflammatory effects of sulfated glycosaminoglycanes in the early phase of bone healing

Schulze, S.; Neuber, C.; Möller, S.; Pietzsch, J.; Schaser, K.-D.; Rammelt, S.

A self-assembled dynamic extracellular matrix-like hydrogel system with multi-scale structures for cell bioengineering applications

Xu, Y.; Rothe, R.; Voigt, D.; Sayed, A.; Huang, C.; Hauser, S.; Lee, P. W.; Cui, M.; Saenz, J. P.; Boccaccini, A. R.; Zheng, K.; Pietzsch, J.; Zhang, Y.

Enzymological characterization of ⁶⁴Cu-labeled neprilysin substrates and their application for modulating the renal clearance of targeted radiopharmaceuticals

Brandt, F.; Ullrich, M.; Wodtke, J.; Kopka, K.; Bachmann, M.; Löser, R.; Pietzsch, J.; Pietzsch, H.-J.; Wodtke, R.

Involved research facilities

  • ZRT

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Dipeptide-derived alkynes as potent and selective irreversible inhibitors of cysteine cathepsins

Behring, L.; Ruiz-Gomez, G.; Trapp, C.; Morales, M.; Wodtke, R.; Köckerling, M.; Kopka, K.; Pisabarro, M. T.; Pietzsch, J.; Löser, R.

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Epigenetic drugs in somatostatin type 2 receptor radionuclide theranostics and radiation transcriptomics in mouse pheochromocytoma models

Ullrich, M.; Richter, S.; Liers, J.; Drukewitz, S.; Friedemann, M.; Kotzerke, J.; Ziegler, C. G.; Nölting, S.; Kopka, K.; Pietzsch, J.

Anti-cancer prodrug cyclophosphamide exerts thrombogenic effects on human venous endothelial cells independent of CYP450 activation – relevance to thrombosis

Krüger-Genge, A.; Köhler, S.; Laube, M.; Haileka, V.; Lemm, S.; Majchrzak, K.; Kammerer, S.; Schulz, C.; Storsberg, J.; Pietzsch, J.; Küpper, J.-H.; Jung, F.

Significance of pulmonary endothelial injury and the role of cyclooxygenase-2 and prostanoid signaling

Nickl, R.; Hauser, S.; Pietzsch, J.; Richter, T.

2022

Towards personalized medicine: one chelator for imaging and therapy with lutetium-177 and actinium-225

Cieslik, P.; Kubeil, M.; Zarschler, K.; Ullrich, M.; Brandt, F.; Anger, K.; Wadepohl, H.; Kopka, K.; Bachmann, M.; Pietzsch, J.; Stephan, H.; Comba, P.

Involved research facilities

  • ZRT

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Case report: Incidentally discovered case of pheochromocytoma as a cause of long COVID-19 syndrome

Ziegler, C. G.; Riediger, C.; Gruber, M.; Kunath, C.; Ullrich, M.; Pietzsch, J.; Nölting, S.; Siepmann, T.; Bornstein, S. R.; Remde, H.; Constantinescu, G.

Exploring nitric oxide (NO)- releasing celecoxib derivatives as modulators of radioresponse in pheochromocytoma cells

Brandt, F.; Ullrich, M.; Seifert, V.; Haase-Kohn, C.; Richter, S.; Knieß, T.; Pietzsch, J.; Laube, M.

Development of a neurotensin-derived 68Ga-labeled PET ligand with high in vivo stability for imaging of NTS1 receptor-expressing tumors

Schindler, L.; Moosbauer, J.; Schmidt, D.; Spruss, T.; Grätz, L.; Lüdeke, S.; Hofheinz, F.; Meister, S.; Echtenacher, B.; Bernhardt, G.; Pietzsch, J.; Hellwig, D.; Keller, M.

Cyclam with a phosphinate-bis(phosphonate) pendant arm is a bone-targeting carrier of copper radionuclides

Pazderová, L.; Benešová, M.; Havlíčková, J.; Vojtíčková, M.; Kotek, J.; Lubal, P.; Ullrich, M.; Walther, M.; Schulze, S.; Neuber, C.; Rammelt, S.; Pietzsch, H.-J.; Pietzsch, J.; Kubíček, V.; Hermann, P.

Nanochips assisted peptide screening for clinical development of CAR-T cell immunotherapy

Anh Nguyen-Le, T.; Bartsch, T.; Wodtke, R.; Brandt, F.; Arndt, C.; Feldmann, A.; Isabel Sandoval Bojorquez, D.; Perez Roig, A.; Ibarlucea, B.; Lee, S.; Baek, C.-K.; Cuniberti, G.; Bergmann, R.; Puentes-Cala, E.; Andrés Soto, J.; T. Kurien, B.; Bachmann, M.; Baraban, L.

Long-term excessive dietary phosphate increases arterial blood pressure, activates the renin-angiotensin-aldosterone system, and stimulates sympathetic tone in mice

Latic, N.; Peitzsch, M.; Zupcic, A.; Pietzsch, J.; Erben, R. G.

Impact of sulfated hyaluronan on bone metabolism in diabetic Charcot neuroarthropathy and degenerative arthritis

Schulze, S.; Neuber, C.; Möller, S.; Hempel, U.; Hofbauer, L. C.; Schaser, K.-D.; Pietzsch, J.; Rammelt, S.

Combining Radiation- with Immunotherapy in Prostate Cancer: Influence of Radiation on T cells

Lindner, D.; Arndt, C.; Loureiro, L. R.; Feldmann, A.; Kegler, A.; Koristka, S.; Berndt, N.; Mitwasi, N.; Bergmann, R.; Frenz, M.; Bachmann, M.

1-(4-Fluorobenzoyl)-9H-carbazole

Laube, M.; König, J.; Köckerling, M.; Knieß, T.

Involved research facilities

  • ZRT

Investigation of radiotracer metabolic stability in vitro with CYP-overexpressing hepatoma cell lines

Lemm, S.; Köhler, S.; Wodtke, R.; Jung, F.; Küpper, J.-H.; Pietzsch, J.; Laube, M.

Targeting CD10 on B-Cell Leukemia Using the Universal CAR T-Cell Platform (UniCAR)

Mitwasi, N.; Arndt, C.; Loureiro, L. R.; Kegler, A.; Fasslrinner, F.; Berndt, N.; Bergmann, R.; HoˇRejší, V.; Rössig, C.; Bachmann, M.; Feldmann, A.

Development and functional characterization of a versatile radio-/immunotheranostic tool for prostate cancer management

Arndt, C.; Bergmann, R.; Striese, F.; Merkel, K.; Máthé, D.; Loureiro, L. R.; Mitwasi, N.; Kegler, A.; Fasslrinner, F.; González Soto, K. E.; Neuber, C.; Berndt, N.; Kovács, N.; Szöllősi, D.; Hegedűs, N.; Tóth, G.; Emmermann, J.-P.; Harikumar, K. B.; Kovacs, T.; Bachmann, M.; Feldmann, A.

Personalized drug testing in human pheochromocytoma/paraganglioma primary cultures

Wang, K.; Schütze, I.; Gulde, S.; Bechmann, N.; Richter, S.; Helm, J.; Lauseker, M.; Maurer, J.; Reul, A.; Spöttl, G.; Klink, B.; William, D.; Knösel, T.; Friemel, J.; Bihl, M.; Weber, A.; Fankhauser, M.; Schober, L.; Vetter, D.; Broglie Däppen, M.; Ziegler, C. G.; Ullrich, M.; Pietzsch, J.; Bornstein, S. R.; Lottspeich, C.; Kroiß, M.; Fassnacht, M.; Wenter, V.; Ladurner, R.; Hantel, C.; Reincke, M.; Eisenhofer, G.; Grossman, A. B.; Pacak, K.; Beuschlein, F.; Auernhammer, C. J.; Pellegata, N.; Nölting, S.

Application of a fluorescence anisotropy-based assay to quantify transglutaminase 2 activity in cell lysates

Hauser, S.; Sommerfeld, P.; Wodtke, J.; Hauser, C.; Schlitterlau, P.; Pietzsch, J.; Löser, R.; Pietsch, M.; Wodtke, R.

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Carboranyl analogues of mefenamic acid and their biological evaluation

Useini, L.; Mojic, M.; Laube, M.; Lönnecke, P.; Dahme, J.; Sárosi, M. B.; Mijatovic, S.; Maksimovic-Ivanic, D.; Pietzsch, J.; Hey-Hawkins, E.

A self-assembled matrix system for cell-bioengineering applications in different dimensions, scales, and geometries

Xu, Y.; Patino Gaillez, M.; Zheng, K.; Voigt, D.; Cui, M.; Kurth, T.; Xiao, L.; Rothe, R.; Hauser, S.; Lee, P. W.; Wieduwild, R.; Lin, W.; Bornhäuser, M.; Pietzsch, J.; Boccaccini, A. R.; Zhang, Y.

The role of transglutaminase 2 in the radioresistance of melanoma cells

Aepler, J.; Wodtke, J.; Wodtke, R.; Haase-Kohn, C.; Löser, R.; Pietzsch, J.; Hauser, S.

Therapeutic Potential of Nitric Oxide releasing Selective Estrogen Receptor Modulators (NO-SERMs) in Malignant Melanoma

Bechmann, N.; Calsina, B.; Richter, S.; Pietzsch, J.

“Clickable” albumin binders for modulating the tumor uptake of targeted radiopharmaceuticals

Brandt, F.; Ullrich, M.; Laube, M.; Kopka, K.; Bachmann, M.; Löser, R.; Pietzsch, J.; Pietzsch, H.-J.; van den Hoff, J.; Wodtke, R.

Involved research facilities

  • PET-Center

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Tumor irradiation in mice with a laser-accelerated proton beam

Kroll, F.; Brack, F.-E.; Bernert, C.; Bock, S.; Bodenstein, E.; Brüchner, K.; Cowan, T.; Gaus, L.; Gebhardt, R.; Helbig, U.; Karsch, L.; Kluge, T.; Kraft, S.; Krause, M.; Leßmann, E.; Masood, U.; Meister, S.; Metzkes-Ng, J.; Nossula, A.; Pawelke, J.; Pietzsch, J.; Püschel, T.; Reimold, M.; Rehwald, M.; Richter, C.; Schlenvoigt, H.-P.; Schramm, U.; Umlandt, M. E. P.; Ziegler, T.; Zeil, K.; Beyreuther, E.

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CRISPR/Cas9 mediated knockout of cyclooxygenase-2 gene inhibits invasiveness in A2058 melanoma cells

Haase-Kohn, C.; Laube, M.; Donat, C.; Belter, B.; Pietzsch, J.

2021

Radiolabeled Silicon-Rhodamines as Bimodal PET/SPECT-NIR Imaging Agents

Kanagasundaram, T.; Laube, M.; Wodtke, J.; Kramer, S. C.; Stadlbauer, S.; Pietzsch, J.; Kopka, K.

Solid-phase synthesis of selectively mono-fluorobenz(o)ylated polyamines as a basis for for the Development of 18F-Labeled Radiotracers

Wodtke, R.; Pietzsch, J.; Löser, R.

Involved research facilities

  • PET-Center

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Targeting acute myeloid leukemia using the RevCAR platform: a programmable, switchable and combinatorial strategy

Kittel-Boselli, E.; González Soto, K. E.; Loureiro, L. R.; Hoffmann, A.; Bergmann, R.; Arndt, C.; Koristka, S.; Mitwasi, N.; Kegler, A.; Bartsch, T.; Berndt, N.; Altmann, H.; Fasslrinner, F.; Bornhäuser, M.; Bachmann, M.; Feldmann, A.

And yet it moves: Oxidation of the Nuclear Autoantigen La/SS-B is the Driving Force for Nucleo-Cytoplasmic Shuttling

Berndt, N.; Bippes, C. C.; Michalk, I.; Bartsch, T.; Arndt, C.; Puentes-Cala, E.; Soto, J. A.; Loureiro, L. R.; Kegler, A.; Bachmann, D.; Gross, J. K.; Gross, T.; Kurien, B.; Scofield, T. R. H.; Farris, A. D.; James, J. A.; Bergmann, R.; Schmitz, M.; Feldmann, A.; Bachmann, M.

Modulation of γ-secretase activity by a carborane-based flurbiprofen analogue

Saretz, S.; Basset, G.; Useini, L.; Laube, M.; Pietzsch, J.; Draca, D.; Maksimović-Ivanić, D.; Trambauer, J.; Steiner, H.; Hey-Hawkins, E.

Conductive hydrogels with dynamic reversible networks for biomedical applications

Xu, Y.; Patino Gaillez, M.; Rothe, R.; Hauser, S.; Voigt, D.; Pietzsch, J.; Zhang, Y.

Two Be or Not Two Be: The Nuclear Autoantigen La/SS-B Is able to form Dimers and Oligomers in a Redox Dependent Manner

Berndt, N.; Bippes, C. C.; Michalk, I.; Bachmann, D.; Bachmann, J.; Puentes-Cala, E.; Bartsch, T.; Loureiro, L. R.; Kegler, A.; Bergmann, R.; Gross, J. K.; Gross, T.; Kurien, B. T.; Scofield, R. H.; Farris, A. D.; James, J. A.; Schmitz, M.; Fahmy, K.; Feldmann, A.; Arndt, C.; Bachmann, M.

Development of an 18F-labelled irreversible inhibitor of transglutaminase 2 as radiometric tool for quantitative expression profiling in cells and tissues

Wodtke, R.; Wodtke, J.; Hauser, S.; Laube, M.; Bauer, D.; Rothe, R.; Neuber, C.; Pietsch, M.; Kopka, K.; Pietzsch, J.; Löser, R.

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Convergent Synthesis of Diversified Reversible Network Leads to Liquid Metal-Containing Conductive Hydrogel Adhesives

Xu, Y.; Rothe, R.; Voigt, D.; Hauser, S.; Cui, M.; Miyagawa, T.; Patino Gaillez, M.; Kurth, T.; Bornhäuser, M.; Pietzsch, J.; Zhang, X.

Radiotherapy enhances uptake and efficacy of 90Y-cetuximab: A preclinical trial

Dietrich, A.; Andreeff, M.; Koi, L.; Bergmann, R.; Schubert, M.; Schreiner, L.; Löck, S.; Sihver, W.; Freudenberg, R.; Hering, S.; Pietzsch, H.-J.; Steinbach, J.; Kotzerke, J.; Baumann, M.; Krause, M.

Involved research facilities

  • PET-Center

Development of a ghrelin receptor inverse agonist for positron emission tomography

Bergmann, R.; Chollet, C.; Els-Heindl, S.; Ullrich, M.; Berndt, N.; Pietzsch, J.; MáThé, D.; Bachmann, M.; Beck-Sickinger, A. G.

Involved research facilities

  • PET-Center

Men who stare at bone: multimodal monitoring of bone healing

Schulze, S.; Rothe, R.; Neuber, C.; Hauser, S.; Ullrich, M.; Pietzsch, J.; Rammelt, S.

HIF2alpha-associated pseudohypoxia promotes radioresistance in pheochromocytoma: insights from 3D models

Seifert, V.; Richter, S.; Bechmann, N.; Bachmann, M.; Ziegler, C. G.; Pietzsch, J.; Ullrich, M.

Screening Arrays of Laminin Peptides on Modified Cellulose for Promotion of Adhesion of Primary Endothelial and Neural Precursor Cells

Wetzel, R.; Hauser, S.; Lin, W.; Berg, P.; Werner, C.; Pietzsch, J.; Kempermann, G.; Zhang, Y.

Response of endothelial cells to gelatin-based hydrogels

Krüger-Genge, A.; Hauser, S.; Neffe, A. T.; Liu, Y.; Lendlein, A.; Pietzsch, J.; Jung, F.

Immunocompatibility and non-thrombogenicity of gelatin-based hydrogels

Krüger-Genge, A.; Tondera, C.; Hauser, S.; Braune, S.; Görs, J.; Roch, T.; Klopfleisch, R.; Neffe, A. T.; Lendlein, A.; Pietzsch, J.; Jung, F.

Radiolabelled Cyclic Bisarylmercury: High Chemical and in vivo Stability for Theranostics

Gilpin, I. M.; Ullrich, M.; Wünsche, T.; Zarschler, K.; Lebeda, O.; Pietzsch, J.; Pietzsch, H.-J.; Walther, M.

A modular, injectable, non-covalently assembled hydrogel system features widescale tunable degradability for controlled release and tissue integration

Rothe, R.; Xu, Y.; Kuriakose Thomas, A.; Meister, S.; Zhang, Y.; Pietzsch, J.; Hauser, S.

2020

Telemedicine pre and post COVID-19: Lessons for commercialization based on previous use cases

Ferenczi, G. L.; Mahmood, A.; Bergmann, R.

  • Open Access Logo Journal of the International Society for Telemedicine and eHealth 8(2020), e8
    DOI: 10.29086/JISfTeH.8.e8

Suppression of Metastatic Melanoma Growth in Lung by Modulated Electro-Hyperthermia Monitored by a Minimally Invasive Heat Stress Testing Approach in Mice

Thomas, M. J.; Major, E.; Benedek, A.; Horvath, I.; Mathe, D.; Bergmann, R.; Szasz, A. M.; Krenacs, T.; Benyo, Z.

Involved research facilities

  • PET-Center

The pyrazolo[3,4-d]pyrimidine-based kinase inhibitor NVP-BHG712: Effects of regioisomers on tumor growth, perfusion, and hypoxia in EphB4-positive A375 melanoma xenografts

Neuber, C.; Tröster, A.; Löser, R.; Belter, B.; Schwalbe, H.; Pietzsch, J.

Three-dimensional cell culture systems in radiopharmaceutical cancer research

Doctor, A.; Seifert, V.; Ullrich, M.; Hauser, S.; Pietzsch, J.

HIF2α supports pro-metastatic behavior in pheochromocytomas/paragangliomas

Bechmann, N.; Moskopp, M. L.; Ullrich, M.; Calsina, B.; Wallace, P. W.; Richter, S.; Friedemann, M.; Langton, K.; Fliedner, S. M. J.; Timmers, H. J. L. M.; Nölting, S.; Beuschlein, F.; Fassnacht, M.; Preijbisz, A.; Pacak, K.; Ghayee, H. K.; Bornstein, S. R.; Dieterich, P.; Pietzsch, J.; Wielockx, B.; Robledo, M.; Qin, N.; Eisenhofer, G.

Development and In Vivo Application of a Water-Soluble Anticancer Copper Ionophore System Using a Temperature-Sensitive Liposome Formulation

Gaál, A.; Garay, T. M.; Horváth, I.; Máthé, D.; Szöllösi, D.; Veres, D. S.; Mbuotidem, J.; Kovacs, T.; Tóvári, J.; Bergmann, R.; Streli, C.; Szakács, G.; Mihály, J.; Varga, Z.; Szoboszlai, N.

Versatile chimeric antigen receptor platform for controllable and combinatorial T cell therapy

Feldmann, A.; Hoffmann, A.; Bergmann, R.; Koristka, S.; Berndt, N.; Arndt, C.; Loureiro, L. R.; Kittel-Boselli, E.; Mitwasi, N.; Kegler, A.; Lamprecht, C.; González Soto, K. E.; Bachmann, M.

The influence of different artificial extracellular matrix implant coatings on the regeneration of a critical size femur defect in rats

Förster, Y.; Schulze, S.; Penk, A.; Neuber, C.; Möller, S.; Hintze, V.; Scharnweber, D.; Schnabelrauch, M.; Pietzsch, J.; Huster, D.; Rammelt, S.

Recent insights in barium-131 as a diagnostic match for radium-223: cyclotron production, separation, labeling and imaging

Reissig, F.; Bauer, D.; Ullrich, M.; Kreller, M.; Pietzsch, J.; Mamat, C.; Kopka, K.; Pietzsch, H.-J.; Walther, M.

Metabolomics, machine learning and immunohistochemistry to predict succinate dehydrogenase mutational status in phaeochromocytomas and paragangliomas

Wallace, P. W.; Conrad, C.; Brückmann, S.; Pang, Y.; Caleiras, E.; Murakami, M.; Korpershoek, E.; Zhuang, Z.; Rapizzi, E.; Kroiss, M.; Gudziol, V.; Timmers, H. J. L. M.; Mannelli, M.; Pietzsch, J.; Beuschlein, F.; Pacak, K.; Robledo, M.; Klink, B.; Peitzsch, M.; Gill, A. J.; Tischler, A. S.; de Krijger, R. R.; Papathomas, T.; Aust, D.; Eisenhofer, G.; Richter, S.

Deuteration versus ethylation – strategies to improve the metabolic fate of a 18F-labeled celecoxib derivative

Laube, M.; Gassner, C.; Neuber, C.; Wodtke, R.; Ullrich, M.; Haase-Kohn, C.; Löser, R.; Köckerling, M.; Kopka, K.; Knieß, T.; Hey-Hawkins, E.; Pietzsch, J.

A radiopharmacologist's and radiochemist's view on targeting the Eph/ephrin receptor tyrosine kinase system

Neuber, C.; Belter, B.; Mamat, C.; Pietzsch, J.

Highly efficient targeting of EGFR-expressing tumor cells with UniCAR T cells via target modules based on Cetuximab®

Jureczek, J.; Feldmann, A.; Bergmann, R.; Arndt, C.; Berndt, N.; Koristka, S.; Loureiro, L. R.; Mitwasi, N.; Hoffmann, A.; Kegler, A.; Bartsch, T.; Bachmann, M.

Extended half-life target module for sustainable UniCAR T-cell treatment of STn-expressing cancers

Loureiro, L. R.; Feldmann, A.; Bergmann, R.; Koristka, S.; Berndt, N.; Máthé, D.; Hegedüs, N.; Szigeti, K.; Videira, P. A.; Bachmann, M.; Arndt, C.

Adjuvant drug-assisted bone healing: advances and challenges in drug delivery approaches

Rothe, R.; Hauser, S.; Neuber, C.; Laube, M.; Schulze, S.; Rammelt, S.; Pietzsch, J.

UniCAR T cell immunotherapy enables efficient elimination of radioresistant cancer cells

Arndt, C.; Loureiro, L. R.; Feldmann, A.; Jureczek, J.; Bergmann, R.; Máthé, D.; Hegedüs, N.; Berndt, N.; Koristka, S.; Metwasi, N.; Fasslrinner, F.; Lamprecht, C.; Kegler, A.; Hoffmann, A.; Bartsch, T.; Köseer, A. S.; Egan, G.; Schmitz, M.; Hořejší, V.; Krause, M.; Dubrovska, A.; Bachmann, M.

Synthesis, radiolabeling and first biological characterization of 18F-labeled xanthine derivatives for PET imaging of Eph receptors

Pretze, M.; Neuber, C.; Kinski, E.; Belter, B.; Köckerling, M.; Caflisch, A.; Steinbach, J.; Pietzsch, J.; Mamat, C.

Involved research facilities

  • PET-Center

Regulation of bone regeneration

Jung, F.; Pietzsch, J.

Carboranyl Derivatives of Rofecoxib with Cytostatic Activity Against Human Melanoma and Colon Cancer Cells

Buzharevski, A.; Paskas, S.; Sárosi, M.-B.; Laube, M.; Lönnecke, P.; Neumann, W.; Murganić, B.; Mijatović, S.; Maksimović-Ivanić, D.; Pietzsch, J.; Hey-Hawkins, E.

The sigma-1 receptor: potential role in the modulation of cellular radiation sensitivity

Belter, B.; Deuther-Conrad, W.; Hofheinz, F.; Bachmann, M.; Brust, P.; Pietzsch, J.

“UniCAR”-modified off-the-shelf NK-92 cells for targeting of GD2-expressing tumour cells

Mitwasi, N.; Feldmann, A.; Arndt, C.; Koristka, S.; Berndt, N.; Jureczek, J.; Loureiro, L.; Bergmann, R.; Máthé, D.; Hegedüs, N.; Kovács, T.; Zhang, C.; Oberoi, P.; Jäger, E.; Seliger, B.; Rössig, C.; Temme, A.; Eitler, J.; Tonn, T.; Schmitz, M.; Hassel, J.; Jäger, D.; Wels, W.; Bachmann, M.

Active Targeting of Dendritic Polyglycerols for Diagnostic Cancer Imaging

Kritee, P.; Neuber, C.; Zarschler, K.; Wodtke, J.; Meister, S.; Rainer, H.; Pietzsch, J.; Stephan, H.

Involved research facilities

  • PET-Center

Versatile Bispidine-based Bifunctional Chelators for 64CuII-Labelling of Biomolecules

Singh, G.; Zarschler, K.; Hunoldt, S.; Santana Martinez, I. I.; Rühl, C.; Matterna, M.; Bergmann, R.; Mathe, D.; Hegedüs, N.; Bachmann, M.; Comba, P.; Stephan, H.

Involved research facilities

  • PET-Center

Ultrasmall silicon nanoparticles as a promising platform for multimodal imaging

Singh, G.; Ddungu, J. L. Z.; Licciardello, N.; Bergmann, R.; de Cola, L.; Stephan, H.

Involved research facilities

  • PET-Center

2019

Introduction of the New Center for Radiopharmaceutical Cancer Research at Helmholtz-Zentrum Dresden-Rossendorf

Kreller, M.; Pietzsch, H.-J.; Walther, M.; Tietze, H.; Kaever, P.; Knieß, T.; Füchtner, F.; Steinbach, J.; Preusche, S.

Synthesis and cyclooxygenase inhibition of sulfonamide-substituted (dihydro)pyrrolo[3,2,1-hi]indoles and their potential prodrugs

Laube, M.; Gassner, C.; Knieß, T.; Pietzsch, J.

Characterization of Tissue Transglutaminase as a Potential Biomarker for Tissue Response toward Biomaterials

Hauser, S.; Wodtke, R.; Tondera, C.; Wodtke, J.; Neffe, A. T.; Hampe, J.; Lendlein, A.; Löser, R.; Pietzsch, J.

Current management of pheochromocytoma/paraganglioma: A guide for the practicing clinician in the era of precision medicine

Nölting, S.; Ullrich, M.; Pietzsch, J.; Ziegler, C. G.; Eisenhofer, G.; Grossman, A.; Pacak, K.

Conventional CARs versus modular CARs

Feldmann, A.; Arndt, C.; Koristka, S.; Berndt, N.; Bergmann, R.; Bachmann, M.

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