Publications of Institute of Radiopharmaceutical Cancer Research
249 Publications2023
Specific and safe targeting of glioblastoma using switchable and logic-gated RevCAR T cells
Abdelfatah Saleh Hassan, H. A.; Mitwasi, N.; Ullrich, M.; Kubeil, M.; Toussaint, M.; Deuther-Conrad, W.; Neuber, C.; Arndt, C.; Rodrigues Loureiro, L. R.; Kegler, A.; González Soto, K. E.; Belter, B.; Rössig, C.; Pietzsch, J.; Frenz, M.; Bachmann, M.; Feldmann, A.
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Frontiers in Immunology 14(2023), 1166169
DOI: 10.3389/fimmu.2023.1166169
Impedimetric Nanobiosensor for the Detection of SARS-CoV-2 Antigens and Antibodies
Sandoval Bojorquez, D. I.; Janićijević, Ž.; Palestina Romero, B.; Oliveros Mata, E. S.; Laube, M.; Feldmann, A.; Kegler, A.; Drewitz, L.; Fowley, C.; Pietzsch, J.; Faßbender, J.; Tonn, T.; Bachmann, M.; Baraban, L.
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Data publication: Impedimetric Nanobiosensor for the Detection of SARS-CoV-2 …
ROBIS: 36555 HZDR-primary research data are used by this (Id 36553) publication
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ACS Sensors 8(2023)2, 576-586
Online First (2023) DOI: 10.1021/acssensors.2c01686
Cited 1 times in Scopus
Solid-Phase Parallel Synthesis of Dual Histone Deacetylase-Cyclooxygenase Inhibitors
Bachmann, L. M.; Hanl, M.; Feller, F.; Sinatra, L.; Schöler, A.; Pietzsch, J.; Laube, M.; Hansen, F. K.
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Molecules 28(2023), 1061
DOI: 10.3390/molecules28031061
Carborane Analogues of Fenoprofen Exhibit Improved Antitumor Activity
Useini, L.; Mojić, M.; Laube, M.; Lönnecke, P.; Mijatović, S. S.; Maksimović-Ivanić, D.; Pietzsch, J.; Hey-Hawkins, E.
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ChemMedChem 18(2023), e202200583
Online First (2022) DOI: 10.1002/cmdc.202200583
Cited 1 times in Scopus
The Impact of Nε-Acryloyllysine Piperazides on the Conformational Dynamics of Transglutaminase 2
Heerwig, A.; Kick, A.; Sommerfeld, P.; Eimermacher, S.; Hartung, F.; Laube, M.; Fischer, D.; Pietzsch, H.-J.; Pietzsch, J.; Löser, R.; Mertig, M.; Pietsch, M.; Wodtke, R.
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International Journal of Molecular Sciences 24(2023), 1650
DOI: 10.3390/ijms24021650
In vitro Cytostatic Effect on Tumor Cells by Carborane-based Dual Cyclooxygenase-2 and 5-Lipoxygenase Inhibitors
Braun, S.; Paskas, S.; Laube, M.; George, S.; Hofmann, B.; Lönnecke, P.; Steinhilber, D.; Pietzsch, J.; Mijatović, S. S.; Maksimović-Ivanić, D.; Hey-Hawkins, E.
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Advanced Therapeutics 6(2023), 2200252
Online First (2022) DOI: 10.1002/adtp.202200252
ISSN: 2366-3987
Cited 2 times in Scopus
Microdialysis reveals anti-inflammatory effects of sulfated glycosaminoglycanes in the early phase of bone healing
Schulze, S.; Neuber, C.; Möller, S.; Pietzsch, J.; Schaser, K.-D.; Rammelt, S.
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International Journal of Molecular Sciences 24(2023), 2077
DOI: 10.3390/ijms24032077
Shell engineering in soft alginate-based capsules for culturing liver spheroids
Peng, X.; Janićijević, Ž.; Lemm, S.; Laube, M.; Pietzsch, J.; Bachmann, M.; Baraban, L.
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Biotechnology Journal (2023)
Online First (2022) DOI: 10.22541/au.165830418.86011497/v1
A self-assembled dynamic extracellular matrix-like hydrogel system with multi-scale structures for cell bioengineering applications
Xu, Y.; Rothe, R.; Voigt, D.; Sayed, A.; Huang, C.; Hauser, S.; Lee, P. W.; Cui, M.; Saenz, J. P.; Boccaccini, A. R.; Zheng, K.; Pietzsch, J.; Zhang, Y.
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Acta Biomaterialia 162(2023), 211-225
DOI: 10.1016/j.actbio.2023.03.015
ISSN: 1742-7061
ISSN: 1878-7568
Enzymological characterization of ⁶⁴Cu-labeled neprilysin substrates and their application for modulating the renal clearance of targeted radiopharmaceuticals
Brandt, F.; Ullrich, M.; Wodtke, J.; Kopka, K.; Bachmann, M.; Löser, R.; Pietzsch, J.; Pietzsch, H.-J.; Wodtke, R.
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Data to NEP paper
ROBIS: 35827 HZDR-primary research data are used by this (Id 35120) publication -
Data to NEP paper
RODARE: 2027 HZDR-primary research data are used by this (Id 35120) publication
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Journal of Medicinal Chemistry 66(2023)1, 516-537
Online First (2023) DOI: 10.1021/acs.jmedchem.2c01472
Dipeptide-derived alkynes as potent and selective irreversible inhibitors of cysteine cathepsins
Behring, L.; Ruiz-Gomez, G.; Trapp, C.; Morales, M.; Wodtke, R.; Köckerling, M.; Kopka, K.; Pisabarro, M. T.; Pietzsch, J.; Löser, R.
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Data files for determination of inhibitory potency of the published compounds …
ROBIS: 36587 is a supplement to this (Id 35046) publication -
Data files for determination of inhibitory potency of the published compounds …
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Data files for determination of inhibitory potency of the published compounds …
RODARE: 2166 HZDR-primary research data are used by this (Id 35046) publication
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Journal of Medicinal Chemistry 66(2023)6, 3818-3851
DOI: 10.1021/acs.jmedchem.2c01360
Epigenetic drugs in somatostatin type 2 receptor radionuclide theranostics and radiation transcriptomics in mouse pheochromocytoma models
Ullrich, M.; Richter, S.; Liers, J.; Drukewitz, S.; Friedemann, M.; Kotzerke, J.; Ziegler, C. G.; Nölting, S.; Kopka, K.; Pietzsch, J.
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Theranostics 13(2023)1, 278-294
DOI: 10.7150/thno.77918
Cited 1 times in Scopus
Significance of pulmonary endothelial injury and the role of cyclooxygenase-2 and prostanoid signaling
Nickl, R.; Hauser, S.; Pietzsch, J.; Richter, T.
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Bioengineering 10(2023)1, 117
DOI: 10.3390/bioengineering10010117
Cited 1 times in Scopus
2022
Towards personalized medicine: one chelator for imaging and therapy with lutetium-177 and actinium-225
Cieslik, P.; Kubeil, M.; Zarschler, K.; Ullrich, M.; Brandt, F.; Anger, K.; Wadepohl, H.; Kopka, K.; Bachmann, M.; Pietzsch, J.; Stephan, H.; Comba, P.
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Data publication: One chelator for imaging and therapy with lutetium-177 and …
ROBIS: 35458 HZDR-primary research data are used by this (Id 35394) publication
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Journal of the American Chemical Society 144(2022)47, 21555-21567
Online First (2022) DOI: 10.1021/jacs.2c08438
Cited 2 times in Scopus
Case report: Incidentally discovered case of pheochromocytoma as a cause of long COVID-19 syndrome
Ziegler, C. G.; Riediger, C.; Gruber, M.; Kunath, C.; Ullrich, M.; Pietzsch, J.; Nölting, S.; Siepmann, T.; Bornstein, S. R.; Remde, H.; Constantinescu, G.
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Frontiers in Endocrinology 13(2022), 967995
DOI: 10.3389/fendo.2022.967995
ISSN: 1664-2392
Exploring nitric oxide (NO)- releasing celecoxib derivatives as modulators of radioresponse in pheochromocytoma cells
Brandt, F.; Ullrich, M.; Seifert, V.; Haase-Kohn, C.; Richter, S.; Knieß, T.; Pietzsch, J.; Laube, M.
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Molecules 27(2022), 6587
DOI: 10.3390/molecules27196587
Cited 1 times in Scopus
Development of a neurotensin-derived 68Ga-labeled PET ligand with high in vivo stability for imaging of NTS1 receptor-expressing tumors
Schindler, L.; Moosbauer, J.; Schmidt, D.; Spruss, T.; Grätz, L.; Lüdeke, S.; Hofheinz, F.; Meister, S.; Echtenacher, B.; Bernhardt, G.; Pietzsch, J.; Hellwig, D.; Keller, M.
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Cancers 14(2022), 4922
DOI: 10.3390/cancers14194922
Cited 1 times in Scopus
Cyclam with a phosphinate-bis(phosphonate) pendant arm is a bone-targeting carrier of copper radionuclides
Pazderová, L.; Benešová, M.; Havlíčková, J.; Vojtíčková, M.; Kotek, J.; Lubal, P.; Ullrich, M.; Walther, M.; Schulze, S.; Neuber, C.; Rammelt, S.; Pietzsch, H.-J.; Pietzsch, J.; Kubíček, V.; Hermann, P.
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Dalton Transactions 51(2022), 9541-9555
DOI: 10.1039/d2dt01172g
Cited 3 times in Scopus
Long-term excessive dietary phosphate increases arterial blood pressure, activates the renin-angiotensin-aldosterone system, and stimulates sympathetic tone in mice
Latic, N.; Peitzsch, M.; Zupcic, A.; Pietzsch, J.; Erben, R. G.
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Biomedicines 10(2022), 2510
DOI: 10.3390/biomedicines10102510
ISSN: 2227-9059
Cited 1 times in Scopus
Impact of sulfated hyaluronan on bone metabolism in diabetic Charcot neuroarthropathy and degenerative arthritis
Schulze, S.; Neuber, C.; Möller, S.; Hempel, U.; Hofbauer, L. C.; Schaser, K.-D.; Pietzsch, J.; Rammelt, S.
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International Journal of Molecular Sciences 23(2022), 15146
DOI: 10.3390/ijms232315146
ISSN: 1422-0067
Cited 1 times in Scopus
Investigation of radiotracer metabolic stability in vitro with CYP-overexpressing hepatoma cell lines
Lemm, S.; Köhler, S.; Wodtke, R.; Jung, F.; Küpper, J.-H.; Pietzsch, J.; Laube, M.
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Cells 11(2022), 2447
DOI: 10.3390/cells11152447
Cited 1 times in Scopus
Personalized drug testing in human pheochromocytoma/paraganglioma primary cultures
Wang, K.; Schütze, I.; Gulde, S.; Bechmann, N.; Richter, S.; Helm, J.; Lauseker, M.; Maurer, J.; Reul, A.; Spöttl, G.; Klink, B.; William, D.; Knösel, T.; Friemel, J.; Bihl, M.; Weber, A.; Fankhauser, M.; Schober, L.; Vetter, D.; Broglie Däppen, M.; Ziegler, C. G.; Ullrich, M.; Pietzsch, J.; Bornstein, S. R.; Lottspeich, C.; Kroiß, M.; Fassnacht, M.; Wenter, V.; Ladurner, R.; Hantel, C.; Reincke, M.; Eisenhofer, G.; Grossman, A. B.; Pacak, K.; Beuschlein, F.; Auernhammer, C. J.; Pellegata, N.; Nölting, S.
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Endocrine-Related Cancer 29(2022)6, 285-306
DOI: 10.1530/ERC-21-0355
ISSN: 1351-0088
Cited 5 times in Scopus
Application of a fluorescence anisotropy-based assay to quantify transglutaminase 2 activity in cell lysates
Hauser, S.; Sommerfeld, P.; Wodtke, J.; Hauser, C.; Schlitterlau, P.; Pietzsch, J.; Löser, R.; Pietsch, M.; Wodtke, R.
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Data to "Application of a fluorescence anisotropy-based assay to quantify …
ROBIS: 34539 HZDR-primary research data are used by this (Id 34410) publication
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International Journal of Molecular Sciences 23(2022)9, 4475
DOI: 10.3390/ijms23094475
Carboranyl analogues of mefenamic acid and their biological evaluation
Useini, L.; Mojic, M.; Laube, M.; Lönnecke, P.; Dahme, J.; Sárosi, M. B.; Mijatovic, S.; Maksimovic-Ivanic, D.; Pietzsch, J.; Hey-Hawkins, E.
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ACS Omega 7(2022), 24282-24291
DOI: 10.1021/acsomega.2c01523
Cited 9 times in Scopus
A self-assembled matrix system for cell-bioengineering applications in different dimensions, scales, and geometries
Xu, Y.; Patino Gaillez, M.; Zheng, K.; Voigt, D.; Cui, M.; Kurth, T.; Xiao, L.; Rothe, R.; Hauser, S.; Lee, P. W.; Wieduwild, R.; Lin, W.; Bornhäuser, M.; Pietzsch, J.; Boccaccini, A. R.; Zhang, Y.
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Small 18(2022), 2104758
Online First (2022) DOI: 10.1002/smll.202104758
Cited 2 times in Scopus
The role of transglutaminase 2 in the radioresistance of melanoma cells
Aepler, J.; Wodtke, J.; Wodtke, R.; Haase-Kohn, C.; Löser, R.; Pietzsch, J.; Hauser, S.
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Cells 11(2022), 1342
DOI: 10.3390/cells11081342
ISSN: 2073-4409
Cited 1 times in Scopus
Therapeutic Potential of Nitric Oxide releasing Selective Estrogen Receptor Modulators (NO-SERMs) in Malignant Melanoma
Bechmann, N.; Calsina, B.; Richter, S.; Pietzsch, J.
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Journal of Investigative Dermatology 142(2022), 2217-2227
Online First (2022) DOI: 10.1016/j.jid.2021.12.028
ISSN: 0022-202X
Cited 6 times in Scopus
“Clickable” albumin binders for modulating the tumor uptake of targeted radiopharmaceuticals
Brandt, F.; Ullrich, M.; Laube, M.; Kopka, K.; Bachmann, M.; Löser, R.; Pietzsch, J.; Pietzsch, H.-J.; van den Hoff, J.; Wodtke, R.
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Data Alb/SSTR2 ligands
ROBIS: 33631 HZDR-primary research data are used by this (Id 33477) publication
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Journal of Medicinal Chemistry 66(2022)1, 710-733
Online First (2021) DOI: 10.1021/acs.jmedchem.1c01791
Cited 8 times in Scopus
Tumor irradiation in mice with a laser-accelerated proton beam
Kroll, F.; Brack, F.-E.; Bernert, C.; Bock, S.; Bodenstein, E.; Brüchner, K.; Cowan, T.; Gaus, L.; Gebhardt, R.; Helbig, U.; Karsch, L.; Kluge, T.; Kraft, S.; Krause, M.; Leßmann, E.; Masood, U.; Meister, S.; Metzkes-Ng, J.; Nossula, A.; Pawelke, J.; Pietzsch, J.; Püschel, T.; Reimold, M.; Rehwald, M.; Richter, C.; Schlenvoigt, H.-P.; Schramm, U.; Umlandt, M. E. P.; Ziegler, T.; Zeil, K.; Beyreuther, E.
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Source Data: Tumour irradiation in mice with a laser-accelerated proton beam …
ROBIS: 33047 HZDR-primary research data are used by this (Id 33044) publication -
Internal Access: Full source data of publication: "Tumor irradiation in mice …
ROBIS: 33048 HZDR-primary research data are used by this (Id 33044) publication
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Nature Physics 18(2022), 316-322
DOI: 10.1038/s41567-022-01520-3
Cited 36 times in Scopus -
Lecture (Conference)
APS DPP, 18.10.2022, Spokane, USA
CRISPR/Cas9 mediated knockout of cyclooxygenase-2 gene inhibits invasiveness in A2058 melanoma cells
Haase-Kohn, C.; Laube, M.; Donat, C.; Belter, B.; Pietzsch, J.
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Cells 11(2022)4, 749
DOI: 10.3390/cells11040749
Cited 4 times in Scopus
2021
Radiolabeled Silicon-Rhodamines as Bimodal PET/SPECT-NIR Imaging Agents
Kanagasundaram, T.; Laube, M.; Wodtke, J.; Kramer, S. C.; Stadlbauer, S.; Pietzsch, J.; Kopka, K.
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Pharmaceuticals 14(2021)11, 1155
Online First (2021) DOI: 10.3390/ph14111155
Cited 3 times in Scopus
Solid-phase synthesis of selectively mono-fluorobenz(o)ylated polyamines as a basis for for the Development of 18F-Labeled Radiotracers
Wodtke, R.; Pietzsch, J.; Löser, R.
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NMR data FBz/FBn polyamines
ROBIS: 33486 HZDR-primary research data are used by this (Id 33187) publication
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Molecules 26(2021)22, 7012
DOI: 10.3390/molecules26227012
Modulation of γ-secretase activity by a carborane-based flurbiprofen analogue
Saretz, S.; Basset, G.; Useini, L.; Laube, M.; Pietzsch, J.; Draca, D.; Maksimović-Ivanić, D.; Trambauer, J.; Steiner, H.; Hey-Hawkins, E.
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Molecules 26(2021), 2843
DOI: 10.3390/molecules26102843
Cited 8 times in Scopus
Conductive hydrogels with dynamic reversible networks for biomedical applications
Xu, Y.; Patino Gaillez, M.; Rothe, R.; Hauser, S.; Voigt, D.; Pietzsch, J.; Zhang, Y.
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Advanced Healthcare Materials 10(2021)11, 2100012
DOI: 10.1002/adhm.202100012
Cited 25 times in Scopus
Development of an 18F-labelled irreversible inhibitor of transglutaminase 2 as radiometric tool for quantitative expression profiling in cells and tissues
Wodtke, R.; Wodtke, J.; Hauser, S.; Laube, M.; Bauer, D.; Rothe, R.; Neuber, C.; Pietsch, M.; Kopka, K.; Pietzsch, J.; Löser, R.
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Data to 18F-AW09
ROBIS: 33487 HZDR-primary research data are used by this (Id 32383) publication
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Journal of Medicinal Chemistry 64(2021)6, 3462-3478
Online First (2021) DOI: 10.1021/acs.jmedchem.1c00096
Cited 13 times in Scopus
Convergent Synthesis of Diversified Reversible Network Leads to Liquid Metal-Containing Conductive Hydrogel Adhesives
Xu, Y.; Rothe, R.; Voigt, D.; Hauser, S.; Cui, M.; Miyagawa, T.; Patino Gaillez, M.; Kurth, T.; Bornhäuser, M.; Pietzsch, J.; Zhang, X.
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Nature Communications 12(2021), 2407
DOI: 10.1038/s41467-021-22675-2
Cited 48 times in Scopus
Development of a ghrelin receptor inverse agonist for positron emission tomography
Bergmann, R.; Chollet, C.; Els-Heindl, S.; Ullrich, M.; Berndt, N.; Pietzsch, J.; MáThé, D.; Bachmann, M.; Beck-Sickinger, A. G.
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Oncotarget 12(2021)5, 33747360
DOI: 10.18632/oncotarget.27895
Cited 3 times in Scopus
Men who stare at bone: multimodal monitoring of bone healing
Schulze, S.; Rothe, R.; Neuber, C.; Hauser, S.; Ullrich, M.; Pietzsch, J.; Rammelt, S.
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Biological Chemistry 402(2021)11, 1397-1413
DOI: 10.1515/hsz-2021-0170
ISSN: 1431-6730
Cited 2 times in Scopus
HIF2alpha-associated pseudohypoxia promotes radioresistance in pheochromocytoma: insights from 3D models
Seifert, V.; Richter, S.; Bechmann, N.; Bachmann, M.; Ziegler, C. G.; Pietzsch, J.; Ullrich, M.
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Cancers 13(2021), 385
DOI: 10.3390/cancers13030385
Cited 7 times in Scopus
Screening Arrays of Laminin Peptides on Modified Cellulose for Promotion of Adhesion of Primary Endothelial and Neural Precursor Cells
Wetzel, R.; Hauser, S.; Lin, W.; Berg, P.; Werner, C.; Pietzsch, J.; Kempermann, G.; Zhang, Y.
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Advanced Biology 5(2021), 1900303
Online First (2021) DOI: 10.1002/adbi.201900303
ISSN: 2366-7478
Cited 2 times in Scopus
Response of endothelial cells to gelatin-based hydrogels
Krüger-Genge, A.; Hauser, S.; Neffe, A. T.; Liu, Y.; Lendlein, A.; Pietzsch, J.; Jung, F.
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ACS Biomaterials Science & Engineering 7(2021), 527-540
DOI: 10.1021/acsbiomaterials.0c01432
Cited 12 times in Scopus
Immunocompatibility and non-thrombogenicity of gelatin-based hydrogels
Krüger-Genge, A.; Tondera, C.; Hauser, S.; Braune, S.; Görs, J.; Roch, T.; Klopfleisch, R.; Neffe, A. T.; Lendlein, A.; Pietzsch, J.; Jung, F.
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Clinical Hemorheology and Microcirculation 77(2021), 335-350
DOI: 10.3233/CH-201028
Cited 9 times in Scopus
Radiolabelled Cyclic Bisarylmercury: High Chemical and in vivo Stability for Theranostics
Gilpin, I. M.; Ullrich, M.; Wünsche, T.; Zarschler, K.; Lebeda, O.; Pietzsch, J.; Pietzsch, H.-J.; Walther, M.
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ChemMedChem 16(2021)17, 2645-2649
Online First (2021) DOI: 10.1002/cmdc.202100131
Cited 1 times in Scopus
A modular, injectable, non-covalently assembled hydrogel system features widescale tunable degradability for controlled release and tissue integration
Rothe, R.; Xu, Y.; Kuriakose Thomas, A.; Meister, S.; Zhang, Y.; Pietzsch, J.; Hauser, S.
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Biomaterials 269(2021), 120637
DOI: 10.1016/j.biomaterials.2020.120637
Cited 7 times in Scopus
2020
The pyrazolo[3,4-d]pyrimidine-based kinase inhibitor NVP-BHG712: Effects of regioisomers on tumor growth, perfusion, and hypoxia in EphB4-positive A375 melanoma xenografts
Neuber, C.; Tröster, A.; Löser, R.; Belter, B.; Schwalbe, H.; Pietzsch, J.
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Molecules 25(2020), 5115
DOI: 10.3390/molecules25215115
Cited 2 times in Scopus
Three-dimensional cell culture systems in radiopharmaceutical cancer research
Doctor, A.; Seifert, V.; Ullrich, M.; Hauser, S.; Pietzsch, J.
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Cancers 12(2020), 2765
DOI: 10.3390/cancers12102765
Cited 20 times in Scopus
HIF2α supports pro-metastatic behavior in pheochromocytomas/paragangliomas
Bechmann, N.; Moskopp, M. L.; Ullrich, M.; Calsina, B.; Wallace, P. W.; Richter, S.; Friedemann, M.; Langton, K.; Fliedner, S. M. J.; Timmers, H. J. L. M.; Nölting, S.; Beuschlein, F.; Fassnacht, M.; Preijbisz, A.; Pacak, K.; Ghayee, H. K.; Bornstein, S. R.; Dieterich, P.; Pietzsch, J.; Wielockx, B.; Robledo, M.; Qin, N.; Eisenhofer, G.
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Endocrine-Related Cancer 27(2020)11, 625-640
DOI: 10.1530/ERC-20-0205
Cited 24 times in Scopus
The influence of different artificial extracellular matrix implant coatings on the regeneration of a critical size femur defect in rats
Förster, Y.; Schulze, S.; Penk, A.; Neuber, C.; Möller, S.; Hintze, V.; Scharnweber, D.; Schnabelrauch, M.; Pietzsch, J.; Huster, D.; Rammelt, S.
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Materials Science and Engineering C 116(2020), 111157
DOI: 10.1016/j.msec.2020.111157
Cited 7 times in Scopus
Recent insights in barium-131 as a diagnostic match for radium-223: cyclotron production, separation, labeling and imaging
Reissig, F.; Bauer, D.; Ullrich, M.; Kreller, M.; Pietzsch, J.; Mamat, C.; Kopka, K.; Pietzsch, H.-J.; Walther, M.
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Pharmaceuticals 13(2020)10, 272
DOI: 10.3390/ph13100272
Cited 15 times in Scopus
Metabolomics, machine learning and immunohistochemistry to predict succinate dehydrogenase mutational status in phaeochromocytomas and paragangliomas
Wallace, P. W.; Conrad, C.; Brückmann, S.; Pang, Y.; Caleiras, E.; Murakami, M.; Korpershoek, E.; Zhuang, Z.; Rapizzi, E.; Kroiss, M.; Gudziol, V.; Timmers, H. J. L. M.; Mannelli, M.; Pietzsch, J.; Beuschlein, F.; Pacak, K.; Robledo, M.; Klink, B.; Peitzsch, M.; Gill, A. J.; Tischler, A. S.; de Krijger, R. R.; Papathomas, T.; Aust, D.; Eisenhofer, G.; Richter, S.
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The Journal of Pathology 251(2020), 378-387
Online First (2020) DOI: 10.1002/path.5472
ISSN: 1096-9896
Cited 19 times in Scopus
Deuteration versus ethylation – strategies to improve the metabolic fate of a 18F-labeled celecoxib derivative
Laube, M.; Gassner, C.; Neuber, C.; Wodtke, R.; Ullrich, M.; Haase-Kohn, C.; Löser, R.; Köckerling, M.; Kopka, K.; Knieß, T.; Hey-Hawkins, E.; Pietzsch, J.
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RSC Advances 10(2020), 38601-38611
DOI: 10.1039/D0RA04494F
Cited 4 times in Scopus
A radiopharmacologist's and radiochemist's view on targeting the Eph/ephrin receptor tyrosine kinase system
Neuber, C.; Belter, B.; Mamat, C.; Pietzsch, J.
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ACS Omega 5(2020)27, 16318-16331
Online First (2020) DOI: 10.1021/acsomega.0c01058
Cited 4 times in Scopus
Adjuvant drug-assisted bone healing: advances and challenges in drug delivery approaches
Rothe, R.; Hauser, S.; Neuber, C.; Laube, M.; Schulze, S.; Rammelt, S.; Pietzsch, J.
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Pharmaceutics 12(2020), 428
DOI: 10.3390/pharmaceutics12050428
ISSN: 1999-4923
Cited 23 times in Scopus
Synthesis, radiolabeling and first biological characterization of 18F-labeled xanthine derivatives for PET imaging of Eph receptors
Pretze, M.; Neuber, C.; Kinski, E.; Belter, B.; Köckerling, M.; Caflisch, A.; Steinbach, J.; Pietzsch, J.; Mamat, C.
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Organic & Biomolecular Chemistry 18(2020)16, 3104-3116
DOI: 10.1039/D0OB00391C
Cited 9 times in Scopus
Regulation of bone regeneration
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Clinical Hemorheology and Microcirculation 73(2020)3, 379-380
DOI: 10.3233/CH-199101
ISSN: 1386-0291
Cited 1 times in Scopus
Carboranyl Derivatives of Rofecoxib with Cytostatic Activity Against Human Melanoma and Colon Cancer Cells
Buzharevski, A.; Paskas, S.; Sárosi, M.-B.; Laube, M.; Lönnecke, P.; Neumann, W.; Murganić, B.; Mijatović, S.; Maksimović-Ivanić, D.; Pietzsch, J.; Hey-Hawkins, E.
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Scientific Reports 10(2020), 4827
DOI: 10.1038/s41598-020-59059-3
Cited 14 times in Scopus
The sigma-1 receptor: potential role in the modulation of cellular radiation sensitivity
Belter, B.; Deuther-Conrad, W.; Hofheinz, F.; Bachmann, M.; Brust, P.; Pietzsch, J.
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Journal of Cellular Biotechnology 6(2020), 13-21
DOI: 10.3233/JCB-209007
Active Targeting of Dendritic Polyglycerols for Diagnostic Cancer Imaging
Kritee, P.; Neuber, C.; Zarschler, K.; Wodtke, J.; Meister, S.; Rainer, H.; Pietzsch, J.; Stephan, H.
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Small 16(2020)7, 1905013
Online First (2019) DOI: 10.1002/smll.201905013
Cited 16 times in Scopus
2019
Synthesis and cyclooxygenase inhibition of sulfonamide-substituted (dihydro)pyrrolo[3,2,1-hi]indoles and their potential prodrugs
Laube, M.; Gassner, C.; Knieß, T.; Pietzsch, J.
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Molecules 24(2019), 3807
DOI: 10.3390/molecules24203807
Cited 7 times in Scopus
Characterization of Tissue Transglutaminase as a Potential Biomarker for Tissue Response toward Biomaterials
Hauser, S.; Wodtke, R.; Tondera, C.; Wodtke, J.; Neffe, A. T.; Hampe, J.; Lendlein, A.; Löser, R.; Pietzsch, J.
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ACS Biomaterials Science & Engineering 5(2019), 5979-5989
DOI: 10.1021/acsbiomaterials.9b01299
ISSN: 2373-9878
Cited 4 times in Scopus
Current management of pheochromocytoma/paraganglioma: A guide for the practicing clinician in the era of precision medicine
Nölting, S.; Ullrich, M.; Pietzsch, J.; Ziegler, C. G.; Eisenhofer, G.; Grossman, A.; Pacak, K.
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Cancers 11(2019), 1505
DOI: 10.3390/cancers11101505
ISSN: 2072-6694
Cited 87 times in Scopus
A theranostic PSMA ligand for PET imaging and retargeting of T cells expressing the universal chimeric antigen receptor UniCAR
Arndt, C.; Feldmann, A.; Koristka, S.; Schäfer, M.; Bergmann, R.; Metwasi, N.; Berndt, N.; Bachmann, D.; Kegler, A.; Schmitz, M.; Puentes-Cala, E.; Soto, J. A.; Ehninger, G.; Pietzsch, J.; Liolios, C.; Wunderlich, G.; Kotzerke, J.; Kopka, K.; Bachmann, M.
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OncoImmunology 8(2019)9, 1659095
Online First (2019) DOI: 10.1080/2162402X.2019.1659095
Cited 20 times in Scopus
Biomaterials in repairing rat femoral defects: in vivo insights from small animal positron emission tomography/computed tomography (PET/CT) studies
Neuber, C.; Schulze, S.; Förster, Y.; Hofheinz, F.; Wodke, J.; Möller, S.; Schnabelrauch, M.; Hintze, V.; Scharnweber, D.; Rammelt, S.; Pietzsch, J.
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Clinical Hemorheology and Microcirculation 73(2019), 177-194
DOI: 10.3233/CH-199208
Cited 8 times in Scopus
Instant kit preparation of 68Ga-radiopharmaceuticals via the hybrid chelator DATA: clinical translation of [68Ga]Ga-DATA-TOC
Sinnes, J. P.; Nagel, J.; Waldron, B. P.; Maina, T.; Nock, B. A.; Bergmann, R. K.; Ullrich, M.; Pietzsch, J.; Bachmann, M.; Baum, P. B.; Rösch, F.
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EJNMMI Research 9(2019), 48
DOI: 10.1186/s13550-019-0516-7
Cited 21 times in Scopus
Cytocompatible, Injectable, and Electroconductive Soft Adhesives with Hybrid Covalent/Noncovalent Dynamic Network
Xu, Y.; Patsis, P. A.; Hauser, S.; Voigt, D.; Rothe, R.; Günther, M.; Cui, M.; Yang, X.; Wieduwild, R.; Eckert, K.; Neinhuis, C.; Akbar, T. F.; Minev, I. R.; Pietzsch, J.; Zhang, J.
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Advanced Science 6(2019), 1802077
Online First (2019) DOI: 10.1002/advs.201802077
Cited 70 times in Scopus
Nitric oxide-releasing selective estrogen receptor modulators (NO-SERMs): a bifunctional approach to improve the therapeutic index
Bechmann, N.; Knieß, T.; Pietzsch, J.
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Journal of Medicinal Chemistry 62(2019), 6525-6539
DOI: 10.1021/acs.jmedchem.9b00171
ISSN: 0022-2623
Cited 11 times in Scopus
Targeting Cyclooxygenase-2 in Pheochromocytoma and Paraganglioma: Focus on Genetic Background
Ullrich, M.; Richter, S.; Seifert, V.; Hauser, S.; Calsina, B.; Martínez-Montes, A. M.; Ter Laak, M.; Ziegler, C. G.; Timmers, H.; Eisenhofer, G.; Robledo, M.; Pietzsch, J.
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Cancers 11(2019), 743
DOI: 10.3390/cancers11060743
ISSN: 2072-6694
Cited 6 times in Scopus
Adjuvant drug-assisted bone healing: Part III – Further strategies for local and systemic modulation
Rothe, R.; Schulze, S.; Neuber, C.; Hauser, S.; Rammelt, S.; Pietzsch, J.
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Clinical Hemorheology and Microcirculation 73(2019), 439-488
DOI: 10.3233/CH-199104
ISSN: 1386-0291
Cited 5 times in Scopus
Adjuvant drug-assisted bone healing: Part II – Modulation of angiogenesis
Rothe, R.; Schulze, S.; Neuber, C.; Hauser, S.; Rammelt, S.; Pietzsch, J.
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Clinical Hemorheology and Microcirculation 73(2019), 409-438
DOI: 10.3233/CH-199103
ISSN: 1386-0291
Cited 4 times in Scopus
Adjuvant drug-assisted bone healing: Part I – Modulation of inflammation
Rothe, R.; Schulze, S.; Neuber, C.; Hauser, S.; Rammelt, S.; Pietzsch, J.
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Clinical Hemorheology and Microcirculation 73(2019), 381-408
DOI: 10.3233/CH-199102
ISSN: 1386-0291
Cited 12 times in Scopus
Impact of Extrinsic and Intrinsic Hypoxia on Catecholamine Biosynthesis in Absence or Presence of Hif2α in Pheochromocytoma Cells
Bechmann, N.; Poser, I.; Seifert, V.; Greunke, C.; Ullrich, M.; Qin, N.; Walch, A.; Peitzsch, M.; Robledo, M.; Pacak, K.; Pietzsch, J.; Richter, S.; Eisenhofer, G.
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Cancers 11(2019), 594
DOI: 10.3390/cancers11050594
ISSN: 2072-6694
Cited 19 times in Scopus
Carboranyl analogues of ketoprofen with cytostatic activity against human melanoma and colon cancer cell lines
Buzharevski, A.; Paskas, S.; Laube, M.; Lönnecke, P.; Neumann, W.; Murganic, B.; Mijatovic, S.; Maksimovic-Ivanic, D.; Pietzsch, J.; Hey-Hawkins, E.
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ACS Omega 4(2019)5, 8824-8833
DOI: 10.1021/acsomega.9b00412
Cited 7 times in Scopus
Limited importance of EphrinA1–ligand, Src kinase, and focal adhesion kinase in EphA2-mediated regulation of metastasis in Mel-Juso and A375 human melanoma cells
Neuber, C.; Herwig, N.; Pietzsch, J.; Belter, B.
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Journal of Cellular Biotechnology 5(2019)1, 11-26
DOI: 10.3233/JCB-189010
ISSN: 2352-3689
Cited 1 times in Scopus
Regulation of A375 melanoma cell adhesion and migration by EphB4 and EphrinB2 –insights from co-culture experiments
Neuber, C.; Laube, M.; Mamat, C.; Belter, B.; Pietzsch, J.
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Journal of Cellular Biotechnology 5(2019)1, 27-42
DOI: 10.3233/JCB-189011
ISSN: 2352-3689
Radiochemical and radiopharmacological characterization of a 64Cu-labeled α-MSH analog conjugated with different chelators
Gao, F.; Sihver, W.; Bergmann, R.; Walther, M.; Stephan, H.; Belter, B.; Neuber, C.; Haase-Kohn, C.; Bolzati, C.; Pietzsch, J.; Pietzsch, H.-J.
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Journal of Labelled Compounds and Radiopharmaceuticals 62(2019)8, 495-509
DOI: 10.1002/jlcr.3728
Cited 6 times in Scopus
Fluorescent Mouse Pheochromocytoma Spheroids Expressing Hypoxia-Inducible Factor 2 alpha: Morphologic and Radiopharmacologic Characterization
Seifert, V.; Liers, J.; Kniess, T.; Richter, S.; Bechmann, N.; Feldmann, A.; Bachmann, M.; Eisenhofer, G.; Pietzsch, J.; Ullrich, M.
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Journal of Cellular Biotechnology 5(2019)2, 135-151
DOI: 10.3233/JCB-199005
ISSN: 2352-3689
Cited 6 times in Scopus
Carboranyl Analogues of Celecoxib with Potent Cytostatic Activity against Human Melanoma and Colon Cancer Cell Lines
Buzharevski, A.; Paskas, S.; Sárosi, M. B.; Laube, M.; Lönnecke, P.; Neumann, W.; Mijatovic, S.; Maksimovic-Ivanic, D.; Pietzsch, J.; Hey-Hawkins, E.
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ChemMedChem 14(2019)3, 315-321
DOI: 10.1002/cmdc.201800685
Cited 16 times in Scopus
Fluorine-18 labeling of S100 proteins for small animal positron emission tomography
Laube, M.; Kniess, T.; Neuber, C.; Haase-Kohn, C.; Pietzsch, J.
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Methods in Molecular Biology 1929(2019), 461-485
DOI: 10.1007/978-1-4939-9030-6_29
ISSN: 1064-3745
Synthesis and preliminary radiopharmacological characterisation of an 11C-labelled azadipeptide nitrile as potential PET tracer for imaging of cysteine cathepsins
Laube, M.; Frizler, M.; Wodtke, R.; Neuber, C.; Belter, B.; Kniess, T.; Bachmann, M.; Gütschow, M.; Pietzsch, J.; Löser, R.
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Journal of Labelled Compounds and Radiopharmaceuticals 62(2019)8, 448-459
DOI: 10.1002/jlcr.3729
Cited 8 times in Scopus
Synthesis, 18F-labelling and radiopharmacological characterisation of the C-terminal 30mer of Clostridium perfringens enterotoxin as a potential claudin-targeting peptide
Löser, R.; Bader, M.; Kuchar, M.; Wodtke, R.; Lenk, J.; Wodtke, J.; Kuhne, K.; Bergmann, R.; Haase-Kohn, C.; Urbanová, M.; Steinbach, J.; Pietzsch, J.
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Amino Acids 51(2019)2, 219-244
Online First (2018) DOI: 10.1007/s00726-018-2657-9
Cited 3 times in Scopus
One-pot Cascade Synthesis of Pyrazole-based Isosteres of Valdecoxib by a [3+2] Cycloaddition/[1,5] Sigmatropic Rearrangement Sequence and Evaluation of their COX Inhibitory Activity
Roscales, S.; Bechmann, N.; Pietzsch, J.; Kniess, T.
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Heterocycles 98(2019)3, 416-428
DOI: 10.3987/COM-19-14048
Cited 1 times in Scopus
2018
Diverse Effects of Phospholipase A2 Receptor Expression on LNCaP and PC-3 Prostate Cancer Cell Growth in vitro and in vivo
Friedemann, M.; Nacke, B.; Hagelgans, A.; Jandeck, C.; Bechmann, N.; Ullrich, M.; Belter, B.; Neuber, C.; Sukocheva, O.; Pietzsch, J.; Menschikowski, M.
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Oncotarget 9(2018), 35983-35996
DOI: 10.18632/oncotarget.26316
Synthesis, characterization and initial biological evaluation of [⁹⁹ᵐTc]Tc-tricarbonyl labeled DPA-α-MSH peptide derivatives for potential melanoma imaging
Gao, F.; Sihver, W.; Bergmann, R.; Belter, B.; Bolzati, C.; Salvarese, N.; Steinbach, J.; Pietzsch, J.; Pietzsch, H.-J.
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ChemMedChem 13(2018)11, 1146-1158
DOI: 10.1002/cmdc.201800110
Cited 7 times in Scopus
Exploring pitfalls of 64Cu‑labeled EGFR‑targeting peptide GE11 as a potential PET tracer
Striese, F.; Sihver, W.; Gao, F.; Bergmann, R.; Walther, M.; Pietzsch, J.; Steinbach, J.; Pietzsch, H.-J.
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Amino Acids 50(2018)10, 1415-1431
DOI: 10.1007/s00726-018-2616-5
Cited 14 times in Scopus
Development of a novel target module redirecting UniCAR T cells to Sialyl Tn-expressing tumor cells
Loureiro, L.; Feldmann, A.; Bergmann, R.; Koristka, S.; Berndt, N.; Arndt, C.; Pietzsch, J.; Novo, C.; Videira, P.; Bachmann, M.
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Blood Cancer Journal 8(2018), 81
DOI: 10.1038/s41408-018-0113-4
Cited 37 times in Scopus
Strain-specific metastatic phenotypes in pheochromocytoma allograft mice
Ullrich, M.; Liers, J.; Peitzsch, M.; Feldmann, A.; Bergmann, R.; Sommer, U.; Richter, S.; Bornstein, S. R.; Bachmann, M.; Eisenhofer, G.; Ziegler, C. G.; Pietzsch, J.
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Endocrine-Related Cancer 25(2018)12, 993-1004
DOI: 10.1530/ERC-18-0136
Cited 7 times in Scopus
From mono- to bivalent: improving theranostic properties of target modules for redirection of UniCAR T cells against EGFR-expressing tumor cells in vitro and in vivo
Albert, S.; Arndt, C.; Koristka, S.; Berndt, N.; Bergmann, R.; Feldmann, A.; Schmitz, M.; Pietzsch, J.; Steinbach, J.; Bachmann, M.
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Oncotarget 9(2018)39, 25597-25616
DOI: 10.18632/oncotarget.25390
Cited 49 times in Scopus
Nε-Acryloyllysine piperazides as irreversible inhibitors of transglutaminase 2 – synthesis, structure-activity relationships and pharmacokinetic profiling
Wodtke, R.; Hauser, C.; Ruiz-Gómez, G.; Jäckel, E.; Bauer, D.; Lohse, M.; Wong, A.; Pufe, J.; Ludwig, F.-A.; Fischer, S.; Hauser, S.; Greif, D.; Pisabarro, M. T.; Pietzsch, J.; Pietsch, M.; Löser, R.
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Journal of Medicinal Chemistry 61(2018)10, 4528-4560
Online First (2018) DOI: 10.1021/acs.jmedchem.8b00286
Cited 22 times in Scopus
Overexpression of receptor tyrosine kinase EphB4 triggers tumor growth and hypoxia in A375 melanoma xenografts: insights from multitracer small animal imaging experiments
Neuber, C.; Belter, B.; Meister, S.; Hofheinz, F.; Bergmann, R.; Pietzsch, H.-J.; Pietzsch, J.
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Molecules 23(2018), 444
DOI: 10.3390/molecules23020444
Cited 11 times in Scopus
Bridging from Brain to Tumor imaging: (S)- and (R)-[18F]Fluspidine for investigation of Sigma-1 Receptors in Tumor-bearing Mice
Kranz, M.; Bergmann, R.; Kniess, T.; Belter, B.; Neuber, C.; Cai, Z.; Deng, G.; Fischer, S.; Steinbach, J.; Zhou, J.; Huang, H.; Brust, P.; Deuther-Conrad, W.; Pietzsch, J.
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Molecules 23(2018)3, 702
DOI: 10.3390/molecules23030702
Cited 7 times in Scopus
Causative treatment of acid aspiration induced acute lung injury – recent trends from animal experiments and critical perspective
Gramatté, J.; Pietzsch, J.; Bergmann, R.; Richter, T.
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Clinical Hemorheology and Microcirculation 69(2018), 187-195
DOI: 10.3233/CH-189113
ISSN: 1386-0291
Cited 4 times in Scopus
Engrafting human regulatory T cells with a flexible modular chimeric antigen receptor technology
Koristka, S.; Kegler, A.; Bergmann, R.; Arndt, C.; Feldmann, A.; Albert, S.; Cartellieri, M.; Ehninger, A.; Ehninger, G.; Middeke, J. M.; Bornhäuser, M.; Schmitz, M.; Pietzsch, J.; Akgün, K.; Ziemssen, T.; Steinbach, J.; Bachmann, M. P.
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Journal of Autoimmunity 90(2018), 116-131
DOI: 10.1016/j.jaut.2018.02.006
Cited 50 times in Scopus
Evaluation of fluorine-18-labelled alpha1(I)-N-telopeptide analogues as substrate-based radiotracers for PET imaging of melanoma-associated lysyl oxidase
Kuchar, M.; Neuber, C.; Belter, B.; Bergmann, R.; Lenk, J.; Wodtke, R.; Kniess, T.; Steinbach, J.; Pietzsch, J.; Löser, R.
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Frontiers in Chemistry 6(2018), 121
DOI: 10.3389/fchem.2018.00121
Cited 4 times in Scopus
Novel Valdecoxib Derivates by Ruthenium-catalyzed 1,3-Dipolar Cycloaddition of Nitrile Oxides with Alkynes - Synthesis and COX-2 Inhibition Affinity.
Roscales, S.; Bechmann, N.; Weiss, D. H.; Köckerling, M.; Pietzsch, J.; Kniess, T.
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MedChemComm 9(2018), 534-544
DOI: 10.1039/c7md00575j
Cited 20 times in Scopus
2017
An orthotopic xenograft model for high-risk non-muscle invasive bladder cancer in mice: influence of mouse strain, tumor cell count, dwell time and bladder pretreatment
Huebner, D.; Rieger, C.; Bergmann, R.; Ullrich, M.; Meister, S.; Toma, M.; Wiedemuth, R.; Temme, A.; Novotny, V.; Wirth, M. P.; Bachmann, M.; Pietzsch, J.; Fuessel, S.
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BMC Cancer 17(2017)1, 790
DOI: 10.1186/s12885-017-3778-3
Cited 14 times in Scopus
Biological characterization of novel nitroimidazole-peptide conjugates in vitro and in vivo.
Bergmann, R.; Splith, K.; Pietzsch, J.; Bachmann, M.; Neundorf, I.
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Journal of Peptide Science 23(2017), 597-609
Online First (2017) DOI: 10.1002/psc.2995
Cited 7 times in Scopus
Retargeting of UniCAR T cells with an in vivo synthesized target module directed against CD19 positive tumor cells
Bachmann, D.; Aliperta, R.; Bergmann, R.; Feldmann, A.; Koristka, S.; Arndt, C.; Loff, S.; Welzel, P. B.; Albert, S.; Kegler, A.; Ehninger, A.; Cartellieri, M.; Ehninger, G.; Bornhäuser, M.; von Bonin, M.; Werner, C.; Pietzsch, J.; Steinbach, J.; Bachmann, M.
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Oncotarget 9(2017), 7487-7500
DOI: 10.18632/oncotarget.23556
Cited 37 times in Scopus
Development of novel target modules for retargeting of UniCAR T cells to GD2 positive tumor cells
Mitwasi, N.; Feldmann, A.; Bergmann, R.; Berndt, N.; Arndt, C.; Koristka, S.; Kegler, A.; Jureczek, J.; Hoffmann, A.; Ehninger, A.; Cartellieri, M.; Albert, S.; Rössig, C.; Ehninger, G.; Pietzsch, J.; Steinbach, J.; Bachmann, M.
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Oncotarget 8(2017), 108584-108603
DOI: 10.18632/oncotarget.21017
Cited 36 times in Scopus
99mTechnetium-based Small Molecule Radiopharmaceuticals and Radiotracers Targeting Inflammation and Infection
Kniess, T.; Laube, M.; Wüst, F.; Pietzsch, J.
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Dalton Transactions 46(2017), 14435-14451
Online First (2017) DOI: 10.1039/c7dt01735a
Cited 18 times in Scopus