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Non-covalent interactions between nucleosides and molecular clips – comparison of phosphate, phosphonate and sulphate containing clips

Raditzky, B.
Water-soluble clips are possible molecules to study the weak, non-covalent interactions, responsible for many biological processes. The association between nucleosides and sulphate containing clips, with naphthalene or anthracene sidewalls, has been studied by time-resolved laser-induced fluorescence spectroscopy with ultrafast pulses (fs-TRLFS). The determined association constants for the 1:1 complexes range from log Ka = 3.9 – 4.2. The measured spectra assumes the appearance of excited state species.
Keywords: moleculare clips, nucleosides, sulphate clips, fs-TRLFS, association
  • Lecture (Conference)
    5th SUPRAPHONE/4th WG Meeting COST D31, 29.-31.05.08, Prague, Czech Republic

Permalink: https://www.hzdr.de/publications/Publ-11308
Publ.-Id: 11308