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Arterial spin labeling spatial coefficient of variation predicts carotid occlusion side

Mutsaerts, H. J.; Petr, J.; Bokkers, R.; Hendrikse, J.; Lazar, R.; Marshall, R.; Asllani, I.
Collateral perfusion has been shown to be of key prognostic importance in carotid steno‐occlusive disease as it prevents irreversible ischemia1, 2. Arterial spin labeling ﴾ASL﴿ may provide a biomarker of collateral perfusion by measuring arterial transit time ﴾ATT﴿ in addition to cerebral blood flow ﴾CBF﴿. However, this leads to longer scanning times, lower signal‐to‐noise ratio3 and higher motion sensitivity4. We have developed a method to estimate the ATT from a single post‐labeling delay ﴾PLD﴿ ASL image using the spatial coefficient of variance ﴾CoV﴿5. Here, we investigate whether the spatial CoV lateralization through collateral perfusion can predict the side of carotid occlusion.
  • Lecture (Conference)
    34th Annual Scientific Meeting of European Society for Magnetic Resonance in Medicine and Biology, 19.10.2017, Barcelona, Spain
  • Abstract in refereed journal
    Magnetic Resonance Materials in Physics, Biology and Medicine 30(2017)Suppl 1, 198
    DOI: 10.1007/s10334-017-0633-0

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Permalink: https://www.hzdr.de/publications/Publ-25846
Publ.-Id: 25846