Publications of Institute of Radiooncology - OncoRay (from 2013)

289 Publications
Assessing robustness of radiomic features by image perturbation
Zwanenburg, A.; Leger, S.; Agolli, L.; Pilz, K.; Troost, E.; Richter, C.; Löck, S.;

Impact of radiation, systemic therapy and Treatment sequencing on survival of patients with melanoma brain metastases
Rauschenberga, R.; Bruns, J.; Brüttinga, J.; Daubner, D.; Lohaus, F.; Zimmer, L.; Forschner, A.; Zips, D.; Hassel, J. C.; Berking, C.; Kaehler, K. C.; Utikal, J.; Gutzmer, R.; Terheyden, P.; Meiss, F.; Rafei-Shamsabadi, D.; Kiecker, F.; Debus, D.; Dabrowski, E.; Arnold, A.; Garzarolli, M.; Kuske, M.; Beissert, S.; Löck, S.; Linn, J.; Troost, E. G. C.; Meier, F.;

Tissue-type mapping of gliomas.
Raschke, F.; Barrick, T. R.; Jones, T.; Yang, G.; Ye, X.; Howe, F. A.;

Technical Note: Experimental verification of magnetic field-induced beam deflection and Bragg peak displacement for MR-integrated proton therapy.
Schellhammer, S. M.; Gantz, S.; Lühr, A.; Oborn, B. M.; Bussmann, M.; Hoffmann, A. L.;

SDF-1/CXCR4 expression is an independent negative prognostic biomarker in patients with head and neck cancer after primary radiochemotherapy
De-Colle, C.; Menegakis, A.; Mönnich, D.; Welz, S.; Boeke, S.; Sipos, B.; Fend, F.; Mauz, P. S.; Tinhofer, I.; Budach, V.; Abu, J. J.; Stuschke, M.; Balermpas, P.; Rödel, C.; Grosu, A. L.; Abdollahi, A.; Debus, J.; Belka, C.; Ganswindt, U.; Pigorsch, S.; Combs, S. E.; Lohaus, F.; Linge, A.; Krause, M.; Baumann, M.; Zips, D.;

Improved effectiveness of stereotactic radiosurgery in large brain metastases by individualized isotoxic dose prescription: an in silico study
Zindler, J. D.; Schiffelers, J.; Lambin, P.; Hoffmann, A. L.;

Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation
Naumann, M.; Pal, A.; Goswami, A.; Lojewski, X.; Japtok, J.; Vehlow, A.; Naujock, M.; Günther, R.; Jin, M.; Stanslowsky, N.; Reinhardt, P.; Sterneckert, J.; Frickenhaus, M.; Pan-Montojo, F.; Storkebaum, E.; Poser, I.; Freischmidt, A.; Weishaupt, J. H.; Holzmann, K.; Troost, D.; Ludolph, A. C.; Boeckers, T. M.; Liebau, S.; Petri, S.; Cordes, N.; Hyman, A. A.; Wegner, F.; Grill, S. W.; Weis, J.; Storch, A.; Hermann, A.;

Differential effects of α-catenin on the invasion and radiochemosensitivity of human colorectal cancer cells
Förster, S.; Hehlgans, S.; Rödel, F.; Otto, B.; Cordes, N.;

Concise Review: Prostate Cancer Stem Cells: Current Understandin
Skvortsov, S.; Skvortsova, I. I.; Tang, D. G.; Dubrovska, A.;

Tissue-type mapping of gliomas
Raschke, F.; Barrick, T. R.; Jones, T. L.; Yang, G.; Ye, X.; Howe, F. A.;

Graphene Oxide Functional Nanohybrids with Magnetic Nanoparticles for Improved Vectorization of Doxorubicin to Neuroblastoma Cells
Lerra, L.; Farfalla, A.; Sanz, B.; Cirillo, G.; Vittorio, O.; Voli, F.; Le Grand, M.; Curcio, M.; Pasquale Nicoletta, F.; Dubrovska, A.; Hampel, S.; Iemma, F.; Goya, G.;

Prophylactic cranial irradiation in stage IV small cell lung cancer: 5 Selection of patients amongst European IASLC and ESTRO experts
Putora, P. M.; Glatzer, M.; Belderbos, J.; Besse, B.; Blackhall, F.; Califano, R.; Cappuzzo, F.; de Marinis, F.; Dziadziuszko, R.; Felip, E.; Faivre-Finn, C.; Früh, M.; Garrido, P.; Le Pechoux, C.; Mcdonald, F.; Nestle, U.; Novello, S.; O‘Brien, M.; Paz Ares, L.; Peeters, S.; Pöttgen, C.; Ramella, S.; Reck, M.; Slotman, B.; Troost, E. G. C.; Houtte, P. V.; Westeel, V.; Widder, J.; Mornex, F.; de Ruysscher, D.;

The role of functional imaging in lung cancer
Bütof, R.; Troost, E. G. C.;

Chronic low dose ethanol induces an aggressive metastatic phenotype in TRAMP mice, which is counteracted by parthenolide
Morel, K.; Ormsby, R.; Solly, E.; Tran, L.; Sweeney, C.; Klebe, S.; Cordes, N.; Sykes, P.;

Including anatomical variations in robust optimization for head and neck proton therapy can reduce the need of adaptation
Cubillos-Mesías, M.; Troost, E. G. C.; Lohaus, F.; Agolli, L.; Rehm, M.; Richter, C.; Stützer, K.ORC

Correction of Geometrical Effects of a Knife-Edge Slit Camera for Prompt Gamma-Based Range Verification in Proton Therapy
Petzoldt, J.; Janssens, G.; Nenoff, L.; Richter, C.; Smeets, J.;

Log file based dose reconstruction and accumulation for 4D adaptive pencil beam scanned proton therapy in a clinical treatment planning system: Implementation and proof-of-concept
Meijers, A.; Jakobi, A.; Stützer, K.; Marmitt, G.; Both, S.; Langendijk, J.; Richter, C.; Knopf, A.;

FMISO-PET-based lymph node hypoxia adds to the prognostic value of tumor only hypoxia in HNSCC patients
Bandurska-Luque, A.; Löck, S.; Haase, R.; Richter, C.; Zöphel, K.; Abolmaali, N.; Seidlitz, A.; Appold, S.; Krause, M.; Steinbach, J.; Kotzerke, J.; Zips, D.; Baumann, M.; Troost, E.;

Competing risks in survival data analysis
Dutz, A.; Löck, S.;

Heterogeneity of γH2AX foci increases in ex vivo biopsies relative to in vivo tumors
Rassamegevanon, T.; Löck, S.; Baumann, M.; Krause, M.; von Neubeck, C.;

Retrospective investigation of the prognostic value of the β1 integrin expression in patients with head and neck squamous cell carcinoma receiving primary radio(chemo)therapy
Cordes, N.; Ney, M.; Beleites, T.; Aust, D.; Baretton, G.; Thames, H.; Baumann, M.; Krause, M.; Löck, S.; Appold, S.;

Molecular imaging using the theranostic agent 197(m)Hg: phantom measurements and Monte Carlo simulations
Freudenberg, R.ORC; Apolle, R.ORC; Walther, M.; Hartmann, H.; Kotzerke, J.

Utility of fiducial markers for target positioning in proton radiotherapy of oesophageal carcinoma
Apolle, R.ORC; Brückner, S.; Frosch, S.; Rehm, M.; Thiele, J.; Valentini, C.; Lohaus, F.; Babatz, J.; Aust, D. E.; Hampe, J.; Troost, E. G. C.ORC

Applicability of a prognostic CT-based radiomic signature model trained on stage I-III non-small cell lung cancer in stage IV non-small cell lung cancer
de Jonga, E.; van Elmpt, W.; Rizzo, S.; Colarieti, A.; Spitaleri, G.; Leijenaar, R.; Jochems, A.; Hendriks, L.; Troost, E.; Reymen, B.; Dingemans, A.-M.; Lambin, P.;

CT imaging during treatment improves radiomic models for patients with locally advanced head and neck cancer
Leger, S.; Zwanenburg, A.; Pilz, K.; Zschaeck, S.; Zöphel, K.; Kotzerke, J.; Schreiber, A.; Zips, D.; Krause, M.; Baumann, M.; Troost, E.; Richter, C.; Löck, S.;

Radiation dose constraints for organs at risk in neuro-oncology; the European Particle Therapy Network consensus
Lambrecht, M.; Eekers, D.; Alapetite, C.; Burnet, N.; Calugaru, V.; Coremans, I.; Fossati, P.; Høyer, M.; Langendijk, J.; Romero, A. M.; Paulsen, F.; Perpar, A.; Renard, L.; de Ruysscher, D.; Timmermann, B.; Vitek, P.; Weber, D.; van der Weide, H.; Whitfield, G.; Wiggenraad, R.; Roelofs, E.; Nyström, P. W.; Troost, E.;

In vivo imaging in the oral cavity by endoscopic optical coherence tomography
Walther, J.; Schnabel, C.; Tetschke, F.; Rosenauer, T.; Golde, J.; Ebert, N.; Baumann, M.; Hannig, C.; Koch, E.;

Independent validation of a new reirradiation risk score (RRRS) for glioma patients predicting post-recurrence survival: A multicenter DKTK/ROG analysis
Niyazi, M.; Adeberg, S.; Kaul, D.; Boulesteix, A.; Bougatf, N.; Fleischmann, D.; Grün, A.; Krämer, A.; Rödel, C.; Eckert, F.; Paulsen, F.; Kessel, K.; Combs, S.; Oehlke, O.; Grosu, A.; Seidlitz, A.; Lattermann, A.; Krause, M.; Baumann, M.; Guberina, M.; Stuschke, M.; Budach, V.; Belka, C.; Debus, J.;

Development and validation of NTCP models for acute side-effects resulting from proton beam therapy of brain tumours
Dutz, A.; Lühr, A.; Agolli, L.; Troost, E. G. C.; Krause, M.; Baumann, M.; Vermeren, X.; Geismar, D.; Schapira, E. F.; Bussière, M.; Daly, J. E.; Bussière, M. R.; Timmermann, B.; Shih, H. A.; Löck, S.;

Keine Überlegenheit der Protonentherapie gegenüber der IMRT beim lokal fortgeschrittenen NSCLC
Dutz, A.; Troost, E. G. C.; Löck, S.;

Union of light ion therapy centers in Europe (ULICE EC FP7) - Objectives and achievements of joint research activities
Pötter, R.; Balosso, J.; Baumann, M.; Bert, C.; Davies, J.; Enghardt, W.; Fossati, P.; Harris, S.; Jones, B.; Krämer, M.; Mayer, R.; Mock, U.; Pullia, M.; Schreiner, T.; Dosanjh, M.; Debus, J.; Orecchia, R.; Georg, D.;

Radiobiological effects and proton RBE determined by wildtype zebrafish embryos
Szabo, E. R.; Brand, M.; Hans, S.; Hideghety, K.; Karsch, L.; Leßmann, E.; Pawelke, J.; Schürer, M.; Beyreuther, E.;

Integrating a low-field open MR scanner with a static proton research beam line: proof of concept
Schellhammer, S. M.ORC; Hoffmann, A. L.; Gantz, S.; Smeets, J.; van der Kraaij, E.; Quets, S.; Pieck, S.; Karsch, L.; Pawelke, J.

Preclinical imaging for establishment and comparison of orthotopic Non-Small Cell Lung Carcinoma: In search for models reflecting clinical scenarios
Aktar, R.; Dietrich, A.; Tillner, F.; Kotb, S.; Löck, S.; Willers, H.; Baumann, M.; Krause, M.; Bütof, R.;

Commissioning of a 4D MRI phantom for use in MR-guided radiotherapy
Schneider, S.; Dolde, K.; Engler, J.; Hoffmann, A.; Pfaffenberger, A.;

Re-irradiation of recurrent gliomas: pooled analysis and validation of an established prognostic score-report of the Radiation Oncology Group (ROG) of the German Cancer Consortium (DKTK)
Combs, S.; Niyazi, M.; Adeberg, S.; Bougatf, N.; Kaul, D.; Fleischmann, D.; Gruen, A.; Fokas, E.; Rodel, C.; Eckert, F.; Paulsen, F.; Oehlke, O.; Grosu, A.; Seidlitz, A.; Lattermann, A.; Krause, M.; Baumann, M.; Guberina, M.; Stuschke, M.; Budach, V.; Belka, C.; Debus, J.; Kessel, K.;

Prostate cancer stem cells: current understanding
Skvortsov, S.; Skvortsova, I. I.; Tang, D. G.; Dubrovska, A.;

Individual Response to Ionizing Radiation and Personalized Radiotherapy
Domina, E.; Philchenkov, A.; Dubrovska, A.;

Long-term quality of life in inoperable non-small cell lung cancer patients treated with conventionally fractionated compared to hyperfractionated accelerated radiotherapy - Results of the randomized CHARTWEL trial
Hechtner, M.; Krause, M.; Konig, J.; Appold, S.; Hornemann, B.; Singer, S.; Baumann, M.;

Cognitive deficits following brain tumor radiation therapy
Buthut, M.; Haussmann, R.; Seidlitz, A.; Krause, M.; Donix, M.;

Reply to “Comment on Methodological accuracy of image-based electron density assessment using dual-energy computed tomography” [Med. Phys. 44, 2429-2437 (2017)]
Möhler, C.ORC; Wohlfahrt, P.ORC; Richter, C.; Greilich, S.ORC

Including anatomical variations in robust optimization for head and neck proton therapy reduces the need of adaptation
Cubillos-Mesías, M.; Troost, E.; Lohaus, F.; Agolli, L.; Rehm, M.; Richter, C.; Stützer, K.;

Dose-guided patient positioning in proton radiotherapy using multicriteria-optimization
Kurz, C.; Süss, P.; Arnsmeyer, C.; Haehnle, J.; Teichert, K.; Landry, G.; Hofmaier, J.; Exner, F.; Hille, L.; Kamp, F.; Thieke, C.; Ganswindt, U.; Valentini, C.; Hölscher, T.; Troost, E.; Krause, M.; Belka, C.; Küfer, K.; Parodi, K.; Richter, C.;

„Radiobiology of Proton Therapy“: results of an international expert workshop
Lühr, A.; von Neubeck, C.; Pawelke, J.; Seidlitz, A.; Peitzsch, C.; Bentzen, S.; Bortfeld, T.; Debus, J.; Deutsch, E.; Langendijk, J.; Löffler, J.; Mohan, R.; Scholz, M.; Sørensen, B.; Weber, D.; Baumann, M.; Krause, M.;

Comparison of different treatment planning approaches for intensity-modulated proton therapy with simultaneous integrated boost for pancreatic cancer
Stefanowicz, S.; Stützer, K.; Zschaeck, S.; Jakobi, A.; Troost, E. G. C.ORC

External validation of an NTCP model for acute esophageal toxicity in locally advanced NSCLC patients treated with intensity-modulated 5 (chemo-)radiotherapy
Dankers, F.; Wijsman, R.; Troost, E.; Tissing-Tan, C.; Kwint, M.; Belderbos, J.; de Ruysscher, D.; Hendriks, L.; de S.-Oei, L.-F.; Rodwell, L.; Dekker, A.; Monshouwer, R.; Hoffmann, A.; Bussink, J.;

Intensity-modulated proton therapy decreases dose to organs at risk in low-grade glioma patients: results of a multicentric in silico ROCOCO trial
Eekers, D.; Roelofs, E.; Cubillos-Mesias, M.; Niel, C.; Smeenk, R.; Minken, A.; Granzier, M.; Janssens, G.; Kaanders, J.; Lambin, P.; Troost, E. G. C.;

Overview of research and therapy facilities for radiobiological experimental work in particle therapy. Report from the European Particle Therapy Network radiobiology group
Dosanjh, M.; Jones, B.; Pawelke, J.ORC; Pruschy, M.; Singers Sørensen, B.

Intratumoral heterogeneity and TERT promoter mutations in progressive/higher-grade meningiomas
Juratli, T. A.; Thiede, C.; Koerner, M. V. A.; Tummala, S. S.; Daubner, D.; Shankar, G. M.; Williams, E. A.; Martinez-Lage, M.; Soucek, S.; Robel, K.; Penson, T.; Krause, M.; Appold, S.; Meinhardt, M.; Pinzer, T.; Miller, J. J.; Krex, D.; Ely, H. A.; Silverman, I. M.; Christiansen, J.; Schackert, G.; Wakimoto, H.; Kirsch, M.; Brastianos, P. K.; Cahill, D. P.;

An Image Reconstruction Framework and Camera Prototype Aimed for Compton Imaging for In-vivo Dosimetry of Therapeutic Ion Beams
Schoene, S.; Enghardt, W.; Fiedler, F.; Golnik, C.; Pausch, G.; Rohling, H.; Kormoll, T.;

Detection Systems for Range Monitoring in Proton Therapy: Needs and Challenges
Pausch, G.; Berthold, J.; Enghardt, W.; Römer, K.; Straessner, A.; Wagner, A.; Werner, T.; Kögler, T.;
  • Lecture (Conference)
    2018 Symposium on Radiation Measurements and Applications (SORMA XVII), 11.-14.06.2018, Ann Arbor, MI, USA
  • Nuclear Instruments and Methods in Physics Research A (2019)
    Online First (2018) DOI: 10.1016/j.nima.2018.09.062

Combined PET/MRI: Global Warming-Summary Report of the 6th International Workshop on PET/MRI, March 27-29, 2017, Tübingen,
Bailey, D. L.; Pichler, B. J.; Gückel, B.; Antoch, G.; Barthel, H.; Bhujwalla, Z. M.; Biskup, S.; Biswal, S.; Bitzer, M.; Boellaard, R.; Braren, R. F.; Brendle, C.; Brindle, K.; Chiti, A.; La Fougère, C.; Gillies, R.; Goh, V.; Goyen, M.; Hacker, M.; Heukamp, L.; Knudsen, G. M.; Krackhardt, A. M.; Law, I.; Morris, J. C.; Nikolaou, K.; Nuyts, J.; Ordonez, A. A.; Pantel, K.; Quick, H. H.; Riklund, K.; Sabri, O.; Sattler, B.; Troost, E.; Zaiss, M.; Zender, L.; Beyer, T.;

Cancer stem cells: Radioresistance, prediction of radiotherapy outcome and specific targets for combined treatments.
Krause, M.; Dubrovska, A.; Linge, A.; Baumann, M.;

PORTAF–postoperative radiotherapy of non-small cell lung cancer: accelerated versus conventional fractionation–study protocol for a randomized controlled trial
Bütof, R.; Simon, M.; Löck, S.; Troost, E.; Appold, S.; Krause, M.; Baumann, M.;

Profile of European proton and carbon ion therapy centers assessed by the EORTC facility questionnaire.
Weber, D. C.; Abrunhosa-Branquinho, A.; Bolsi, A.; Kacperek, A.; Dendale, R.; Geismar, D.; Bachtiary, B.; Hall, A.; Heufelder, J.; Herfarth, K.; Debus, J.; Amichetti, M.; Krause, M.; Orecchia, R.; Vondracek, V.; Thariat, J.; Kajdrowicz, T.; Nilsson, K.; Grau, C.;

Radiation Resistance in KRAS-Mutated Lung Cancer Is Enabled by Stem-like Properties Mediated by an Osteopontin-EGFR Pathway.
Wang, M.; Han, J.; Marcar, L.; Black, J.; Liu, Q.; Li, X.; Nagulapalli, K.; Sequist, L. V.; Mak, R. H.; Benes, C. H.; Hong, T. S.; Gurtner, K.; Krause, M.; Baumann, M.; Kang, J. X.; Whetstine, J. R.; Willers, H.;

Heat shock protein 70 and tumor-infiltrating NK cells as prognostic indicators for patients with squamous cell carcinoma of the head and neck after radiochemotherapy: A multicentre retrospective study of the German Cancer Consortium
Stangl, S.; Tontcheva, N.; Sievert, W.; Shevtsov, M.; Niu, M.; Schmid, T.; Pigorsch, S.; Combs, S.; Haller, B.; Balermpas, P.; Rödel, F.; Rödel, C.; Fokas, E.; Krause, M.; Linge, A.; Lohaus, F.; Baumann, M.; Tinhofer, I.; Budach, V.; Stuschke, M.; Grosu, A.; Abdollahi, A.; Debus, J.; Belka, C.; Maihöfer, C.; Mönnich, D.; Zips, D.; Multhoff, G.;

Tumor heterogeneity determined with a γH2AX foci assay: A study in human head and neck squamous cell carcinoma (hHNSCC) models
Rassamegevanon, T.; Löck, S.; Range, U.; Krause, M.; Baumann, M.; von Neubeck, C.;

Development of a genetic sensor that eliminates p53 deficient cells
Mircetic, J.; Dietrich, A.; Paszkowski-Rogacz, M.; Krause, M.; Buchholz, F.;

Comparison of detection methods for HPV status as a prognostic marker for loco-regional control after radiochemotherapy in patients with HNSCC.
Linge, A.; Schötz, U.; Löck, S.; Lohaus, F.; von Neubeck, C.; Gudziol, V.; Nowak, A.; Tinhofer, I.; Budach, V.; Sak, A.; Stuschke, M.; Balermpas, P.; Rödel, C.; Bunea, H.; Grosu, A.; Abdollahi, A.; Debus, J.; Ganswindt, U.; Lauber, K.; Pigorsch, S.; Combs, S.; Mönnich, D.; Zips, D.; Baretton, G.; Buchholz, F.; Krause, M.; Belka, C.; Baumann, M.;

Neoadjuvant radiochemotherapy decreases the total amount of tumor infiltrating lymphocytes, but increases the number of CD8+/Granzyme B plus (GrzB) cytotoxic T-cells in rectal cancer
Jarosch, A.; Sommer, U.; Bogner, A.; Reißfelder, C.; Weitz, J.; Krause, M.; Folprecht, G.; Baretton, G. B.; Aust, D. E.;

Stereotactic radiosurgery for brainstem metastases : In experienced hands a good treatment option with excellent risk-benefit ratio
Khademalhosseini, Z.; Khademolhosseini, M.; Kummer, B.; Krause, M.;

SDF-1/CXCR4 expression in head and neck cancer and outcome after postoperative radiochemotherapy
De-Colle, C.; Mönnich, D.; Welz, S.; Boeke, S.; Sipos, B.; Fend, F.; Mauz, P.-S.; Tinhofer, I.; Budach, V.; Jawad, J. A.; Stuschke, M.; Balermpas, P.; Rödel, C.; Grosu, A.-L.; Abdollahi, A.; Debus, J.; Bayer, C.; Belka, C.; Pigorsch, S.; Combs, S. E.; Lohaus, F.; Linge, A.; Krause, M.; Baumann, M.; Zips, D.; Menegakis, A.;

The PD-1/PD-L1 axis and human papilloma virus in patients with head and neck cancer after adjuvant chemoradiotherapy: A multicentre study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG).
Balermpas, P.; Rödel, F.; Krause, M.; Linge, A.; Lohaus, F.; Baumann, M.; Tinhofer, I.; Budach, V.; Sak, A.; Stuschke, M.; Gkika, E.; Grosu, A.-L.; Abdollahi, A.; Debus, J.; Stangl, S.; Ganswindt, U.; Belka, C.; Pigorsch, S.; Multhoff, G.; Combs, S. E.; Welz, S.; Zips, D.; Lim, S. Y.; Rödel, C.; Fokas, E.;

Prompt gamma spectroscopy for range control with CeBr3.
Martins, P. M.; Bello, R. D.; Rinscheid, A.; Roemer, K.; Werner, T.; Enghardt, W.; Pausch, G.; Seco, J.;

Prospective data registration and clinical trials for particle therapy in Europe
Langendijk, J.; Orrechhia, R.; Haustermans, K.; Zips, D.; Balosso, J.; Lievens, Y.; Weber, D.; Grau, C.; Troost, E.;

Practice patterns of image guided particle therapy in Europe: a 2016 survey of the European Particle Therapy Network (EPTN)
Bolsi, A.; Peroni, M.; Amelio, D.; Dasu, A.; Stock, M.; Toma-Dasu, I.; Witt Nyström, P.; Hoffmann, A. L.;

Research facility for radiobiological studies at the University Proton Therapy Dresden
Beyreuther, E.; Baumann, M.; Enghardt, W.; Helmbrecht, S.; Karsch, L.; Krause, M.; Pawelke, J.; Schreiner, L.; Schürer, M.; von Neubeck, C.;

Whole exome sequencing identifies mTOR and KEAP1 as potential targets for radiosensitization of HNSCC cells refractory to EGFR and β1 integrin inhibition
Klapproth, E.; Dickreuter, E.; Zakrzewski, F.; Seifert, M.; Petzold, A.; Dahl, A.; Schröck, E.; Klink, B.; Cordes, N.;

Relative biological effectiveness in proton beam therapy – current knowledge and future challenges
Lühr, A.; von Neubeck, C.; Krause, M.; Troost, E. G. C.;

Prognostic Value of Head and Neck Tumor Proliferative Sphericity From 3’-Deoxy-3’-[18F] Fluorothymidine Positron Emission Tomography
Majdoub, M.; Hoeben, B.; Troost, E. G. C.; Oyen, W.; Kaanders, J.; Le Rest, C.; Visser, E.; Visvikis, D.; Hatt, M.;

Melanoma brain metastases: Local therapies, targeted therapies, immune checkpoint inhibitors and their combinations- chances and challenges
Kuske, M.; Rauschenberg, R.; Garzarolli, M.; Meredyth-Stewart, M.; Beissert, S.; Troost, E.; Glitza, I.; Meier, F.;

Inter-centre variability of CT-based range prediction in particle therapy: Survey-based evaluation
Taasti, V.; Bäumer, C.; Dahlgren, C.; Deisher, A.; Ellerbrock, M.; Free, J.; Gora, J.; Kozera, A.; Lomax, T.; de Marzi, L.; Molinelli, S.; Teo, K.; Wohlfahrt, P.; Petersen, J.; Muren, L.; Hansen, D.; Richter, C.;

Clinical feasibility of single-source dual-spiral 4D dual-energy CT for proton treatment planning within the thoracic region
Wohlfahrt, P.ORC; Troost, E. G. C.; Hofmann, C.; Richter, C.; Jakobi, A.

A comparative study of machine learning methods for time-To-event survival data for radiomics risk modelling
Leger, S.; Zwanenburg, A.; Pilz, K.; Lohaus, F.; Linge, A.; Zöphel, K.; Kotzerke, J.; Schreiber, A.; Tinhofer, I.; Budach, V.; Sak, A.; Stuschke, M.; Balermpas, P.; Rödel, C.; Ganswindt, U.; Belka, C.; Pigorsch, S.; Combs, S.; Mönnich, D.; Zips, D.; Krause, M.; Baumann, M.; Troost, E.; Löck, S.; Richter, C.;

The EPTN consensus-based atlas for CT- and MR-based contouring in Neuro-Oncology
Eekers, D.; In 'T Ven, L.; Roelofs, E.; Postma, A.; Alapetite, C.; Burnet, N.; Calugaru, V.; Compter, I.; Coremans, I.; Hoyer, M.; Lambrecht, M.; Romero, A.; Paulsen, F.; Perpar, A.; de Ruysscher, D.; Renard, L.; Vitek, P.; Weber, D.; van der Weide, H.; Whitfield, G.; Wiggenraad, R.; Nyström, P.; Timmermann, B.; Troost, E.;

Evidence on the efficacy of primary radiosurgery or stereotactic radiotherapy for drug-resistant non-neoplastic focal epilepsy in adults: a systematic review
Eekers, D.; Pijnappel, E.; Schijns, O.; Colon, A.; Hoeben, A.; Zindler, J.; Postma, A.; Hoffmann, A.; Lambin, P.; Troost, E.;

The posterior cerebellum, a new organ at risk?
Eekers, D. B. P.; In 'T Ven, L.; Deprez, S.; Jacobi, L.; Roelofs, E.; Hoeben, A.; Lambin, P.; de Ruysscher, D.; Troost, E. G. C.;

Photon vs. proton radiochemotherapy: effects on brain tissue volume and perfusion
Petr, J.; Platzek, I.; Hofheinz, F.; Mutsaerts, H.; Asllani, I.; van Osch, M.; Seidlitz, A.; Krukowski, P.; Gommlich, A.; Beuthien-Baumann, B.; Jentsch, C.; Maus, J.; Troost, E.; Baumann, M.; Krause, M.; van den Hoff, J.;

Residual tumour hypoxia in head-and-neck cancer patients undergoing primary radiochemotherapy, final results of a prospective trial on repeat FMISO-PET imaging
Löck, S.; Perrin, R.; Seidlitz, A.; Bandurska-Luque, A.; Zschaeck, S.; Zöphel, K.; Krause, M.; Steinbach, J.; Kotzerke, J.; Zips, D.; Troost, E. G. C.; Baumann, M.;

Quality assessment of delineation and dose planning of early breast cancer patients included in the randomized Skagen Trial 1
Francolini, G.; Thomsen, M. S.; Yates, E. S.; Kirkove, C.; Jensen, I.; Blix, E. S.; Kamby, C.; Nielsen, M. H.; Krause, M.; Berg, M.; Mjaaland, I.; Schreiber, A.; Kasti, U. M.; Boye, K.; Offersen, B. V.;

Therapeutic options to overcome tumor hypoxia in radiation oncology
Troost, E.; Koi, L.; Yaromina, A.; Krause, M.;

Dosimetric evidence confirms computational model of magnetic field induced dose distortions of therapeutic proton beams
Schellhammer, S. M.ORC; Gantz, S.; Lühr, A.; Oborn, B. M.; Bussmann, M.; Hoffmann, A. L.

Inclusion of Incidental Radiation Dose to the Cardiac Atria and Ventricles Does Not Improve the Prediction of Radiation Pneumonitis in Advanced-Stage Non-Small Cell Lung Cancer Patients Treated With Intensity Modulated Radiation Therapy
Wijsman, R.; Dankers, F. J. W. M.; Troost, E. G. C.; Hoffmann, A. L.; van der Heijden, E. H. F. M.; de Geus-Oei, L.-F.; Bussink, J.;

Experimental verification of particle-range prediction in biological tissue by single- and dual-energy computed tomography
Möhler, C.ORC; Russ, T.; Wohlfahrt, P.ORC; Elter, A.; Runz, A.; Richter, C.; Greilich, S.

Towards ion beam therapy based on laser plasma accelerators
Karsch, L.; Beyreuther, E.ORC; Enghardt, W.ORC; Gotz, M.; Masood, U.; Schramm, U.; Zeil, K.; Pawelke, J.ORC

Modeling in vivo relative biological effectiveness in particle therapy for clinically relevant endpoints
Lühr, A.; von Neubeck, C.; Helmbrecht, S.; Baumann, M.; Enghardt, W.; Krause, M.;

Modeling tumor control probability for spatially inhomogeneous risk of failure based on clinical outcome data
Lühr, A.; Löck, S.; Jakobi, A.; Stützer, K.; Bandurska-Luque, A.; Vogelius, I. R.; Enghardt, W.; Baumann, M.; Krause, M.;

EGFR-amplification plus gene expression profiling predicts response to combined radiotherapy with EGFR-inhibition: a preclinical trial in 10 HNSCC-tumour-xenograft models
Koi, L.; Löck, S.; Linge, A.; Thurow, C.; Hering, S.; Baumann, M.; Krause, M.; Gurtner, K.;

Development and validation of a gene signature for patients with head and neck carcinomas treated by postoperative radio(chemo)therapy
Schmidt, S.; Linge, A.; Zwanenburg, A.; Leger, S.; Lohaus, F.; Krenn, C.; Appold, S.; Gudziol, V.; Nowak, A.; von Neubeck, C.; Tinhofer, I.; Budach, V.; Sak, A.; Stuschke, M.; Balermpas, P.; Rödel, C.; Bunea, H.; Grosu, A.-L.; Abdollahi, A.; Debus, J.; Ganswindt, U.; Belka, C.; Pigorsch, S.; Combs, S. E.; Mönnich, D.; Zips, D.; Baretton, G. B.; Buchholz, F.; Baumann, M.; Krause, M.; Löck, S.;

Potential proton and photon dose degradation in advanced head and neck cancer patients by intra-therapy changes
Stützer, K.; Jakobi, A.; Bandurska-Luque, A.; Barczyk, S.; Arnsmeyer, C.; Löck, S.; Richter, C.;

Dynamics of rectal balloon implant shrinkage in prostate VMAT: Influence on anorectal dose and late rectal complication risk
Vanneste, B.; van Wijk, Y.; Lutgens, L.; van Limbergen, E.; van Lin, E.; van de Beek, K.; Lambin, P.; Hoffmann, A.;

Dual-energy CT based proton range prediction in head and pelvic tumor patients
Wohlfahrt, P.ORC; Möhler, C.ORC; Stützer, K.; Greilich, S.; Richter, C.

Sensitivity of a prompt-gamma slit-camera to detect range shifts for proton treatment verification
Nenoff, L.; Priegnitz, M.; Janssens, G.; Petzoldt, J.; Trezza, A.; Smeets, J.; Pausch, G.; Richter, C.;

Melanoma Brain Metastases
Brütting, J.; Rauschenberg, R.; Troost, E. G. C.; Meier, F.; Garzarolli, M.;

Photons, protons or carbon ions for stage I non-small cell lung cancer - results of the multicentric ROCOCO in silico study
Wink, K. C. J.; Roelofs, E.; Simone, C. B.; Dechambre, D.; Santiago, A.; van der Stoep, J.; Dries, W.; Smits, J.; Avery, S.; Ammazzalorso, F.; Jansen, N.; Jelen, U.; Solberg, T.; de Ruysscher, D.; Troost, E. G. C.;

Impact of robust treatment planning on single- and multi-field optimized plans for proton beam therapy of unilateral head and neck target volumes
Cubillos-Mesías, M.; Baumann, M.; Troost, E. G. C.; Lohaus, F.; Löck, S.; Richter, C.; Stützer, K.;

Evaluation of stopping-power prediction by dual- and single-energy computed tomography in an anthropomorphic ground-truth phantom
Wohlfahrt, P.ORC; Möhler, C.ORC; Richter, C.; Greilich, S.

Proton radiography for inline treatment planning and positioning verification of small animals
Müller, J.; Neubert, C.; von Neubeck, C.; Baumann, M.; Krause, M.; Enghardt, W.; Bütof, R.; Dietrich, A.; Lühr, A.;

On the equivalence of image-based dual-energy CT methods for the determination of electron density and effective atomic number in radiotherapy
Möhler, C.ORC; Wohlfahrt, P.ORC; Richter, C.; Greilich, S.

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