Foto: Research Program Cancer Research ©Copyright: Mario BengsImaging and Radiooncology

Health > Cancer Research - All Topics

Foto: Pharmaceutical production in the clean room ©Copyright: HZDR/Rainer WeisflogIn Germany, 500,000 people are diagnosed with cancer every year. New, faster, and primarily more gentle diagnostic and therapeutic procedures can help to fight the disease and to save lifes.

Cancer research at the HZDR addresses the following topics: The scientists conduct research, for example, on new radiopharmaceuticals for the diagnosis of cancer and for the characterization of cancer tissue and, as a further development, also investigate substances for the cancer therapy of tomorrow. Our research has already resulted in the development of new substances. Two radiopharmaceuticals are officially approved and registered pursuant to the pharmaceutical law. These substances, which are produced at the HZDR and subsequently distributed on the market, are needed for the detection of tumors and metastases with a PET camera (PET = Positron Emission Tomography). That is also possible in Dresden – patients can be examined utilizing a full-body scan PET/MRI system which is the first of its kind to have been approved for patients in Germany. HZDR scientists are further developing and improving these innovative imaging procedures which are used in oncology.

They are also investigating particle acceleration with the help of innovative laser technologies. The objective: Making proton-therapy centers smaller while, at the same time, lowering the costs through more powerful lasers and with pulsed magnetic fields. Researchers are also aiming on monitoring irradiation of patients with proton beams in real time.

The HZDR is part of the Competence Network for Radiation Research (KVSF, promoted by the BMBF). This alliance promotes the sustainability of competences in the field of radiation research, in particular, by fostering young scientists.

Important partners are the TU Dresden (Dresden University of Technology) and the University Hospital Carl Gustav Carus Dresden. We jointly operate the OncoRay Center. More information on collaborations with Dresden and Heidelberg partners


Objectives

  • Development and application of new technologies for the diagnosis and therapy of cancer
  • Establishment of laser-accelerated ions in radiation oncology
  • Monitoring and controlling tumor radiation in real time
  • Continued development of individualized and tolerable therapy forms

Press Releases


Involved HZDR institutes


Collaborations


Contacts


Publications

  • Hadova, K.; Gündel, D.; Knieß, T. et al.
    Protein phosphatase 2A impairs cardiac uptake of glucose in the mammalian heart
    Naunyn-Schmiedeberg's Archives of Pharmacology (2026) (10.1007/s00210-026-05617-x)
  • Simbirova, A.; Thomas, E.; Hessel, F. et al.
    Radiation Therapy in Adolescents and Young Adults (AYA): Contemporary Evidence on Utilization, Outcomes, Late Toxicities, and Second Malignant Neoplasms – A Comprehensive Systematic Review and Synthesis
    Radiotherapy and Oncology 221(2026), 111638 (10.1016/j.radonc.2026.111638)
  • Ferreira Machado, J. d. M.; Zarschler, K.; Knieß, T. et al.
    A translational journey in Germany: From literature to local implementation of [89Zr]Zr-DFO-trastuzumab
    Nuklearmedizin (2026) (10.1055/a-2883-7600)
  • Linge, A.; Lohaus, F.; Appold, S. et al.
    De-escalation of adjuvant radio(chemo)therapy for patients with HPV-positive head and neck squamous cell carcinoma: study protocol for a phase I trial to reduce late toxicity (DELPHI)
    BMC Cancer 26(2026), 542 (10.1186/s12885-026-16050-x)
  • Jacobs, J.; van Weerd, E.; Moerman, A. et al.
    Identifying Best Practices for RTTs and Dosimetrists: A Delphi Consensus Study on Standardizing Workflows in Proton Therapy
    Technical Innovations & Patient Support in Radiation Oncology 38(2026), 100411 (10.1016/j.tipsro.2026.100411)
  • Dalfovo, D.; Sassorossi, C.; de Paolis, E. et al.
    LANTERN-XGB: An Interpretable Multi-Modal Machine Learning for Improving Clinical Decision-Making in Lung Cancer
    International Journal of Molecular Sciences 27(2026), 3128 (10.3390/ijms27073128)
  • Lebbink, F.; Alvares Michael, E.; Kornek, A. et al.
    Comparison of gantry-less magnetic resonance guided proton therapy with photon therapy for hepatocellular carcinoma patients
    Physics and Imaging in Radiation Oncology 39(2026), 100967 (10.1016/j.phro.2026.100967)
  • Aulsebrook, M. L.; Pascali, G.; Tuck, K. L. et al.
    Next-Gen 18F-Relay Reagent: Optimising [18F]Ethanesulfonyl Fluoride
    International Journal of Molecular Sciences 27(2026)9, 3982 (10.3390/ijms27093982)
  • Mari, M.; Patinec, V.; Alvarado, R. et al.
    Neutralizing copper(II) complex charge through sulfonation: a new chelator for 64Cu radiopharmaceuticals
    Inorganic Chemistry Communications 189(2026), 116782 (10.1016/j.inoche.2026.116782)
  • Karpinski, M. J.; Civan, C.; Rauscher, I. et al.
    New prostate cancer risk groups by PSMA-PET (PPP3): an international, retrospective, registry-based cohort study
    Lancet Oncology 27(2026)4, 480-490 (10.1016/S1470-2045(26)00016-1)
  • Benčurová, K.; Gündel, D.; Kieler, M. et al.
    PET/MRI with 89Zr-labelled antibodies provides insights into altered antibody pharmacokinetics in the chick embryo model
    European Journal of Pharmaceutical Sciences 221(2026), 107520 (10.1016/j.ejps.2026.107520)
  • Schädlich, J.; Selg, C.; Haase-Kohn, C. et al.
    An approach toward radioiodination and radiopharmacological evaluation of a carborane-containing analog of indomethacin
    Molecules 31(2026), 1944 (10.3390/molecules31111944)
  • Kaufmann, J.; Trommer, M.; Rühle, A. et al.
    Radiotherapy in patients with NSCLC developing progressive disease during immune checkpoint inhibition: Abscopal responses and survival
    Clinical and Translational Radiation Oncology 58(2026), 101125 (10.1016/j.ctro.2026.101125)
  • Grey, A.; Thiem, J.; Wahl, H. et al.
    Incidence and time course of new contrast-enhancing lesions on MRI after proton versus photon radiotherapy in glioma patients
    Neuroradiology 68(2026), 517-531 (10.1007/s00234-025-03829-1)
  • Curvello, R.; Hauser, S.; Seifert, M. et al.
    GOT1 inhibition induces extracellular matrix remodelling in pancreatic cancer
    Advanced Science 13(2026)13, e16578 (10.1002/advs.202516578)
  • Turhan, G.; Irem Cetin, A.; Padrela, B. E. et al.
    Cerebral Blood Flow and Time of Exchange Measurements Using Multi-TE Blood-Brain Barrier Arterial Spin Labeling MRI in IDH Mutational Subgroups of Gliomas
    Magnetic Resonance Materials in Physics, Biology and Medicine (2026) (10.1007/s10334-026-01348-5)
  • Essed, R. A.; Wamelink, I. J. H. G.; Petr, J. et al.
    Amide Proton Transfer and Arterial Spin Labeling for Non-Invasive Molecular Stratification of Glioma: A Multi-Dataset Imaging Biomarker Study
    Neuroradiology 68(2026), 1387-1401 (10.1007/s00234-026-04006-8)
  • Sonam, S.; Mojić, M.; Laube, M. et al.
    nido-carborane conjugates with ibuprofen, flurbiprofen and fenoprofen: synthesis, characterization, COX inhibition potential and anticancer activity
    Journal of Inorganic Biochemistry 280(2026), 113282 (10.1016/j.jinorgbio.2026.113282)
  • Paul, S.; Bera, A.
    Enriching BODIPY Triplet States via Ruthenium(II) Conjugation for Improved Photodynamic Therapy
    Journal of Medicinal Chemistry 69(2026)2, 721-743 (10.1021/acs.jmedchem.5c02024)
  • Yoshizuka, K.; Kubeil, M.; Stephan, H.
    Characterization of macrocyclic host-guest systems by liquid-liquid extraction
    Journal of Inclusion Phenomena and Macrocyclic Chemistry 106(2026), 265-278 (10.1007/s10847-026-01341-4)
  • Kuchar, M.; Zessin, J.; Kopka, K. et al.
    Bestimmung von Kupfer in der Qualitätskontrolle von Radiopharmaka bei kupfergestützten Radiofluorierungen
    Nuklearmedizin 65(2026)2, L27
  • Lai, T. H.; Dukic-Stefanovic, S.; Deuther-Conrad, W. et al.
    Fluorinated derivatives of AG-881 for Positron Emission Tomography detection of mutated Isocitrate Dehydrogenase 1
    Pharmaceuticals 19(2026)5 (10.3390/ph19050660)
  • Busch-Casler, J.; Teichert, A.; Bach, F. et al.
    RWD120 Making Health Data Trustees Sustainable: An Overview of Potential Business and Financing Models
    Value in Health 28(2026)12, S628 (10.1016/j.jval.2025.09.2870)
  • Kiß, O.; Penuelas, I.; Rey, A. et al.
    Highlight selection of radiochemistry and radiopharmacy developments by editorial board
    EJNMMI Radiopharmacy and Chemistry 11(2026), 26 (10.1186/s41181-026-00443-1)
  • Tanderup, K.; Kirby, A.; Eriksen, J. et al.
    ESTRO’s principles for environmental sustainability in the radiation oncology community
    Radiotherapy and Oncology 217(2026), 111384 (10.1016/j.radonc.2026.111384)
  • Trommer, M.; Rühle, A.; Ehret, F. et al.
    Sex-specific differences in abscopal responses to combined radiotherapy and immune checkpoint inhibition–insights from a multicenter study
    Frontiers in Immunology 16(2026), 1699362 (10.3389/fimmu.2025.1699362)
  • Brühlmann, S. A.; Walther, M.; Kopka, K. et al.
    CopperNostics – here we are now, entertain us!
    Pharmaceuticals 19(2026)2, 321 (10.3390/ph19020321)
  • Brühlmann, S. A.; Brandt, F.; Walther, M. et al.
    Cyclotron production of 67Ga using electroplated 68Zn targets on gold and gold-coated aluminum backings
    Applied Radiation and Isotopes 233(2026), 112607 (10.1016/j.apradiso.2026.112607)
  • Chen, O.; Vovk, O.; Polishchuk, N. et al.
    Adaptation to Arginine Deprivation Leads to a More Aggressive, Therapy-Resistant Phenotype in HNSCC Cells
    Biomolecules 15(2025)6, 900 (10.3390/biom15060900)
  • Valentini, C.; Perwein, T.; Bison, B. et al.
    Haematotoxicity of Craniospinal Radiochemotherapy for Metastatic Paediatric High-Grade Glioma
    Clinical Oncology 48(2025), 103956 (10.1016/j.clon.2025.103956)
  • Sagerer, A.; Eyüpoglu, I. Y.; Juratli, T. A. et al.
    Context-specifi c targeting of focal adhesion kinase in brain tumors: lessons from glioblastoma and neurofi bromatosis type 2-mutant meningioma
    Frontiers in Oncology 15(2025), 1724278 (10.3389/fonc.2025.1724278)
  • Ramirez Parra, M.; Dietrich, A.; Pfeifer, M. et al.
    Comparative analysis of molecular targeted radiosensitizers in 2D and 3D cancer cell line models
    Acta Oncologica 64(2025), 1631 (10.2340/1651-226X.2025.43916)
  • Metzner, M.; Longarino, F. K.; Ackermann, B. et al.
    Accuracy of a helium-beam radiography system based on thin pixel detectors for an anthropomorphic head phantom
    Medical Physics 52(2025), 4757 (10.1002/mp.17786)
  • Rabasco Meneghetti, A.; Ligero Hernández, M.; Kühn, J.-P. et al.
    End-to-end prediction of clinical outcomes in head and neck squamous cell carcinoma with foundation model-based multiple instance learning
    BMC Artificial Intelligence 1(2025)1, 3 (10.1186/s44398-025-00003-8)
  • Löck, S.; Koi, L.; Gurtner, K. et al.
    Application of a preclinical 18-gene classifier to patients with locally advanced HNSCC
    Clinical and Translational Radiation Oncology 56(2025), 101067 (10.1016/j.ctro.2025.101067)
  • Bütof, R.; Koi, L.; Löck, S. et al.
    Accelerated vs. conventionally fractionated postoperative radiotherapy of non-small cell lung cancer – final results of the prematurely terminated PORTAF trial
    Strahlentherapie und Onkologie 202(2026), 299-306 (10.1007/s00066-025-02422-y)
  • Trommer, M.; Rühle, A.; Lamrani, A. et al.
    Radiotherapy-induced abscopal effects in immune checkpoint inhibitor-refractory metastatic disease: results from a large multicenter real-world cohort study
    OncoImmunology 15(2026)1, 2610529 (10.1080/2162402X.2025.2610529)
  • Vipin, A.; Xiao Yuan Chen, J.; Tee, M. et al.
    Cerebral haemodynamics and white matter hyperintensities: findings using non-invasive brain imaging
    The Journal of Prevention of Alzheimer's Disease 13(2026)1 (10.1016/j.tjpad.2026.100479)
  • Schädlich, J.; Ullrich, M.; Haase-Kohn, C. et al.
    Radioiodination of two carborane-based dual cyclooxygenase 2/5-lipoxygenase inhibitors and their in vitro and in vivo evaluation
    ChemBioChem 27(2026)7, e202600004 (10.1002/cbic.202600004)
  • Populaire, P.; Simoes, R.; Nenoff, L. et al.
    Terminology Proposal for Adaptive Particle Therapy Classification and Strategies
    International Journal of Particle Therapy 19(2026), 101293 (10.1016/j.ijpt.2025.101293)
  • Tonmoy, T. H.; Seçkin, S.; Hoffmann, M. et al.
    Enhanced Refractive Index Sensitivity of Linearly Assembled Gold Nanoantennae for Biosensing Applications
    Small 22(2026)9, e10159 (10.1002/smll.202510159)
  • Nieder, D.; Cela, I.; Zhao, X. et al.
    Dual‐function, Reusable, and Flexible Thermal Interface for Kinetic Monitoring of In Vitro Bioassays
    Small Methods 10(2026)3, e01243 (10.1002/smtd.202501243)
  • Maus, J.; Nitschke, J.; Nikulin, P. et al.
    Automatic Delineation of Tumor Spheroids in Microscopic Images Using Deep-Learning
    ACS Measurement Science Au 6(2026)2, 411-420 (10.1021/acsmeasuresciau.5c00172)
  • Padrela, B. E.; Tecelão, S.; Kirsebomd, B.-E. et al.
    Blood-brain barrier water exchange in relation to amyloid, cognition and cerebrovascular burden
    NeuroImage Clinical 49(2026), 103926 (10.1016/j.nicl.2025.103926)
  • Schönberg, P. Y.; Muñoz-Ovalle, Á.; Paszkowski-Rogacz, M. et al.
    A pooled CRISPR screen identifies the Tα2 enhancer element as a driver of TRA expression in a subset of mature human T lymphocytes
    Frontiers in Immunology 16(2025), 1536003 (10.3389/fimmu.2025.1536003)
  • Nakao, M.; Schwengfelder, J.; Richter, C. et al.
    Comparison of two established approaches for generating Hounsfield look-up tables for CT-based SPR prediction
    Medical Physics 53(2025)1, e70236 (10.1002/mp.70236)
  • Palkowitsch, M.; LS, K.; Hennings, F. et al.
    Model validation confirms variable relative biological effectiveness and elevated periventricular sensitivity after proton therapy of brain tumors
    Radiotherapy and Oncology 214(2026), 111271 (10.1016/j.radonc.2025.111271)
  • von der Grün, J.; Regnery, S.; Hörner-Rieber, J. et al.
    Multicenter analysis of MRI-guided, stereotactic body radiotherapy as ablative treatment for lymph nodal metastases of the abdomen and pelvis
    Radiotherapy and Oncology 214(2026), 111237 (10.1016/j.radonc.2025.111237)
  • Ferdinandus, S.; Rühle, A.; Lamrani, A. et al.
    Abscopal effects in malignant melanoma patients treated with radiotherapy and immune checkpoint inhibition: analysis of a large observational multicenter study
    Journal for ImmunoTherapy of Cancer 13(2025)10, e012717 (10.1136/jitc-2025-012717)
  • Bozorgmehr, F.; Chung, I.; Fischer, J. et al.
    Reconsidering palliative radiotherapy in addition to PD-1 blockade for non-small cell lung cancer: results from the FORCE phase II trial (AIO/YMO-TRK-0415)
    Clinical & Experimental Metastasis 42(2025)5, 42 (10.1007/s10585-025-10358-x)
  • Meattini, I.; Aznar, M.; Boldrini, L. et al.
    Repositioning Radiation Oncology at the centre of integrated oncology care: a manifesto of the European Society for Radiotherapy and Oncology (ESTRO)
    Radiotherapy and Oncology 210(2025), 111035 (10.1016/j.radonc.2025.111035)
  • Wittenstein, J.; Apolle, R.; Scharffenberg, M. et al.
    Dual-energy computed tomography derived pulmonary blood volume: association with pulmonary blood flow
    Respiratory Research 26(2025), 293 (10.1186/s12931-025-03374-8)
  • Boutier, H.; Kogler, J.; Rodrigues Loureiro, L. R. et al.
    Novel Immunotheranostic FAP-Inhibitor Target Modules for Imaging and Elimination of FAP-positive Cells by UniCAR T-cells
    OncoImmunology 14(2025)1, 2598908 (10.1080/2162402X.2025.2598908)
  • Horst, F. E.; Schüller, A.; Kapsch, R.-P. et al.
    Study of the over-response of radiochromic films in ultra-high dose rate and dose per pulse electron beams
    Physics in Medicine and Biology 71(2026), 045020 (10.1088/1361-6560/ae47b6)
  • Arndt, P.; Morton, L.; Briese, M. et al.
    Vascular and Neural Transcriptomics Reveal Stage‐Dependent Pathways to Inflammation and Cognitive Dysfunction in a Rat Model of Hypertension
    Journal of the American Heart Association 14(2025), e040710 (10.1161/JAHA.125.040710)
  • Blei, M. K.; Waurick, L.; Drobot, B. et al.
    Development of four new diaza macrocycles with regioisomeric diazine carboxylic acid sidearms for stable complexation of lanthanum-133, actinium-225 and lead-203/-212 with focus on barium-131 and radium-223/-224
    Nuclear Medicine and Biology 150-151(2025), 109122 (10.1016/j.nucmedbio.2025.109122)
  • Blei, M. K.; Hajduová, K.; Novy, Z. et al.
    Preclinical Evaluation of 203Pb- and 212Pb-Labeled mcp-PSMA Ligands for Radionuclide Theranostics of Prostate Cancer
    Nuclear Medicine and Biology 150-151(2025), 109097 (10.1016/j.nucmedbio.2025.109097)
  • Franchi, S.; Tosato, M.; Pozzo, S. et al.
    Large Chelators for Large Radiometals: Endeavors to Complex Radium-223 and Barium-131 to Advance Targeted Alpha Therapy and Theranostics of Cancer
    Nuclear Medicine and Biology 150-151(2025), 109123 (10.1016/j.nucmedbio.2025.109123)
  • Giesel, F.; Körber, S.; Hadaschik, B. et al.
    The German Cancer Consortium (DKTK) multi-center prospective phase 1/2 68Ga-PSMA-11 PET-imaging trial in newly-diagnosed high-risk prostate cancer: Safety and diagnostic accuracy compared to histopathology and their impact on patient management
    European Journal of Nuclear Medicine and Molecular Imaging 53(2025), 2994-3006 (10.1007/s00259-025-07540-4)
  • Berthold, J.; Nenoff, L.; Bertschi, S. et al.
    Feasibility of in-vivo 4D prompt-gamma treatment verification in proton therapy for pancreatic cancer
    Physics and Imaging in Radiation Oncology (2026) (10.1016/j.phro.2026.101027)
  • Nikulin, P.; Hoberück, S.; Apostolova, I. et al.
    A convolutional neural network for fully automated total metabolic tumor volume delineation in patients with aggressive Non-Hodgkin lymphoma
    European Journal of Nuclear Medicine and Molecular Imaging 53(2026), 5074-5087 (10.1007/s00259-026-07810-9)
  • Kuhne, K.; Strohbach, L.; Neuber, C. et al.
    Development of cathepsin B-activatable cell-penetrating peptides for tumor targeting
    ACS Pharmacology & Translational Science 9(2026)4, 966-996 (10.1021/acsptsci.5c00746)
  • Bertschi, S.; Perotti Bernardini, G.; Berthold, J. et al.
    Prompt gamma imaging vs. range probing: Experimental comparison of two range verification approaches for proton therapy
    Medical Physics 52(2025)12, e70142 (10.1002/mp.70142)
  • Krönke, T.; Blei, M. K.; Ullrich, M. et al.
    Lanthanum-133 and iodine-123 as diagnostic counterparts to actinium-225 radioconjugates in a small animal PET/SPECT study with mcp-PSMA-ligands
    Nuclear Medicine and Biology 150-151(2025)Suppl., 109291 (10.1016/j.nucmedbio.2025.109291)
  • Mastropasqua, F.; Teresa Lisi, A.; Crouzier, L. et al.
    Development of Second-Generation Phenoxyethylpiperidines as Potent Sigma-1 Receptor Agonists with Neuroprotective Potential for Alzheimer’s Disease
    Journal of Medicinal Chemistry 69(2026)4, 4613-4628 (10.1021/acs.jmedchem.5c03240)
  • Mastropasqua, F.; Ludwig, F.-A.; Abate, C.
    A Full-Spectrum Evaluation of Sigma-1 Receptor (S1R) Positron Emission Tomography (PET) Radioligands from Binding Affinity to Clinical Imaging
    Molecules 30(2025)21, 4296 (10.3390/molecules30214296)
  • Kogler, J.; Donat, C.; Trommer, J. et al.
    Synthesis and preclinical evaluation of FAP-targeting radiotracers for PET and optical imaging
    EJNMMI Radiopharmacy and Chemistry 10(2025), 77 (10.1186/s41181-025-00398-9)
  • Craig, A.; Sachse, F.; Laube, M. et al.
    PET and SPECT Tracer Development via Copper-Mediated Radiohalogenation of Divergent and Stable Aryl-Boronic Esters
    Pharmaceutics 17(2025)7, 837 (10.3390/pharmaceutics17070837)
  • Krönke, T.; Ullrich, M.; Blei, M. K. et al.
    Diagnostic Twins: Exploring the Radiohybrid Concept with Iodine−123 and Lanthanum−133 for PSMA-Targeted SPECT and PET Imaging
    Journal of Medicinal Chemistry 69(2026) (10.1021/acs.jmedchem.6c00161)
  • Azizova, A.; Prysiazhniuk, Y.; Cakmak, M. et al.
    Visual versus Region-of-Interest Based Diffusion Evaluation and their Diagnostic Impact in Adult-Type Diffuse Gliomas
    Neuroradiology 68(2026), 503-515 (10.1007/s00234-025-03832-6)
  • Burger, E.-M.; Hill, C.; Wodtke, R. et al.
    In vitro characterization of the published glypican 3 targeting peptide TJ12P2 reveals a lack of specificity and potency
    Pharmaceuticals 18(2025)11, 1656 (10.3390/ph18111656)
  • Laube, M.; Roscales, S.; Pietzsch, J. et al.
    Nitrosoarenes as versatile precursors for 18F-fluorination
    ACS Omega 11(2026), 32905-32911 (10.1021/acsomega.6c02349)
  • Arlt, E.; Bley, N.; Rausch, A. et al.
    Sex determines the Natural Killer cell-mediated immunity against Pancreatic Cancer
    OncoImmunology 15(2026)1, 2645298 (10.1080/2162402X.2026.2645298)
  • Sonam, S.; Mojić, M.; Gordić, V. et al.
    Novel Ruthenacarborane−NSAID Conjugates
    Molecules 30(2025)21, 4153 (10.3390/molecules30214153)
  • Lakshmi, K.; Jutrzenka-Trzebiatowski, A.; Rodrigues Loureiro, L. R. et al.
    Automated GMP-Compatible Production of Universal CAR Tregs for Organ-Targeted Tolerance Induction
    Journal of Translational Medicine 23(2025)1, 1399 (10.1186/s12967-025-07431-0)
  • Kubeil, M.; Stephan, H.
    Cytotoxicity of Metal-containing Carbon Monoxide-Releasing Molecules: A Current Assessment
    Journal of Inorganic Biochemistry 277(2026), 113235 (10.1016/j.jinorgbio.2026.113235)
  • Toyohara, J.; Elsinga, P.; Todde, S. et al.
    Highlight selection of radiochemistry and radiopharmacy developments by editorial board
    EJNMMI Radiopharmacy and Chemistry 10(2025), 65 (10.1186/s41181-025-00387-y)
  • Maqbool, M.; Gündel, D.; Liow, J.-S. et al.
    Evaluation of deuterated [¹⁸F]JHU94620 for imaging cannabinoid type 2 receptors in rodent and monkey brain
    Journal of Cerebral Blood Flow and Metabolism 45(2025)12, 2417-2427 (10.1177/0271678X251371377)
  • Gabriel, A.; Moeckli, R.; Beyreuther, E. et al.
    New modalities for ultra-high dose rate irradiation and FLASH experiments
    Physics and Imaging in Radiation Oncology 36(2025), 10086 (10.1016/j.phro.2025.100861)
  • Franchi, S.; Asti, M.; Blei, M. K. et al.
    Heavy Alkaline Earth Radiometals for Cancer Theranostics: Coordination and Radiochemistry of Radium-223 and Barium-131 with Kryptofix 22-Based Chelators
    Inorganic Chemistry 64(2025), 22422-22440 (10.1021/acs.inorgchem.5c03908)
  • Rogasch, J. M. M.; Mikolajczak, J.; Hellwig, D. et al.
    PET und KI: Ein narrativer Überblick
    Angewandte Nuklearmedizin 48(2025)03, 204-212 (10.1055/a-2385-3773)
  • García Rivas, I.; Fernández Prieto, A.; Vázquez Regueiro, P. et al.
    Performance of a CeBr₃ scintillator coupled to a photomultiplier tube with an active voltage divider under high bremsstrahlung fluences
    Journal of Instrumentation 20(2025)11, P11016 (10.1088/1748-0221/20/11/P11016)
  • Skjerdal, K.; Kögler, T.; Lionheart, W. et al.
    Range verification in proton therapy with computational prompt gamma-ray spectroscopy: A Monte Carlo study
    Radiation Physics and Chemistry 238(2025), 113096 (10.1016/j.radphyschem.2025.113096)
  • Brühlmann, S. A.; Walther, M.; Zhutova, N. et al.
    From Bench to Batch: Scaling Up Copper-67 Production via the 70Zn(p,α)67Cu Nuclear Reaction
    Radiochimica Acta 114(2026)2, 85-94 (10.1515/ract-2025-0083)
  • Nexhipi, S.; Suckert, T.; Soltwedel, J. et al.
    Cell-specific analysis of microglia following partial brain proton irradiation in mice
    Clinical and Translational Radiation Oncology 54(2025), 101003 (10.1016/j.ctro.2025.101003)
  • Ueberham, L.; Deuther-Conrad, W.; Lönnecke, P. et al.
    Development of Carborane-Based Halogenated Naphthyridinone-Analogues as Cannabinoid Receptor Type 2 (CB2R) Ligands
    ChemMedChem 20(2025)17, e202500251 (10.1002/cmdc.202500251)
  • Hegering, R.; Nexhipi, S.; Suckert, T. et al.
    Radiation-induced changes of reactive astrocyte distribution in mice as a late response to partial-brain proton irradiation
    Acta Oncologica 64(2025), 902-908 (10.2340/1651-226X.2025.44056)
  • Bobić, M.; Bushe, D. H.; Lee, H. et al.
    Comparison of clinically applicable cone beam computed tomography strategies for online adaptive proton therapy of prostate cancer
    Physics and Imaging in Radiation Oncology 36(2025), 100858 (10.1016/j.phro.2025.100858)
  • Nenoff, L.; Eberhardt, A.; Bütof, R. et al.
    Technical note: Systematic optimization for the rapid generation of high-quality online-adapted proton therapy plans in a commercial treatment planning system
    Radiotherapy and Oncology 217(2026), 111415 (10.1016/j.radonc.2026.111415)
  • Đorđević, B.; Baraban, L.; Janićijević, Ž.
    Bioresorbable Electrodes in Implantable Electronic Healthcare Devices
    Frontiers in Bioengineering and Biotechnology 13(2025), 1666446 (10.3389/fbioe.2025.1666446)
  • Tee, M.; Dijsselhof, M. B. J.; Jun Yi Chong, E. et al.
    Effect of Metabolic Syndrome Severity on Cerebral Haemodynamics and Cognition in Community-Based Cohort Atherosclerosis
    Atherosclerosis 409(2025), 120472 (10.1016/j.atherosclerosis.2025.120472)
  • Pehlivan, J.; Beyreuther, E.; Horst, F. E. et al.
    Electron Spin Resonance Measurements of Radiation-Induced Radicals under Conventional and Ultra-High Dose Rate Electron Irradiation
    Physics in Medicine and Biology 71(2026)1, 015016 (10.1088/1361-6560/ae2db6)
  • Krönke, T.; Trommer, J.; Ullrich, M. et al.
    “Precision on two wheels” – Structural refinement of ⁶⁴Cu- and ⁶⁸Ga-labeled bicyclic peptides targeting nectin-4 for improved tumor imaging: from preclinical development to first-in-human application
    Journal of Medicinal Chemistry 68(2025)20, 21962-21987 (10.1021/acs.jmedchem.5c02371)
  • Kahya, U.; Lukiyanchuk, V.; Gorodetska, I. et al.
    Disruption of glutamine transport uncouples the NUPR1 stress-adaptation program and induces prostate cancer radiosensitivity
    Cell Communication and Signaling 23(2025), 351 (10.1186/s12964-025-02344-3)
  • Tisi, M.; Bolzonella, M.; Caresana, M. et al.
    Secondary neutron dose measurements at the DRACO laser-driven ion source
    Scientific Reports 15(2025), 20161 (10.1038/s41598-025-05442-x)
  • Gambetta, V.; Stützer, K.; Richter, C.
    Current status and upcoming developments for online adaptive proton therapy enabling a closed feedback loop for near real-time adaptation
    Frontiers in Oncology 15(2025), 1660605 (10.3389/fonc.2025.1660605)
  • Prysiazhniuk, Y.; Duarte Armindo, R.; Alexander, S. et al.
    Age-Related Changes in Cerebral Blood Flow and Arterial Transit Time in Children: Insights from Single- and Multi-delay ASL
    Neuroradiology 67(2025), 3335-3348 (10.1007/s00234-025-03794-9)
  • Klinghammer, S.; Tonmoy, T. H.; Janićijević, Ž. et al.
    Hemocompatible Coatings of Catheters Equipped with Electrochemical Sensors for Real-Time Monitoring of Critical Parameters in the Blood
    ACS Applied Polymer Materials 7(2025)14, 9349-9362 (10.1021/acsapm.5c01708)
  • Prysiazhniuk, Y.; Alexander, S.; Duarte Armindo, R. et al.
    Comparative Evaluation of Single- and Multi-Delay Arterial Spin Labeling MRI in Preterm Neonates
    NeuroImage 321(2025), 121511 (10.1016/j.neuroimage.2025.121511)
  • Kast, V. J.; Hauser, S.; Nadernezhad, A. et al.
    A biomaterial-based platform of pancreatic cancer reveals kallikrein-related peptidase 6 (KLK6) as a mediator of neutrophil recruitment and immunosuppression
    Biomaterials 324(2026), 123456 (10.1016/j.biomaterials.2025.123456)
  • Ahmed, A.; Peng, X.; Boutier, H. et al.
    Exploring Morphology of Thermoplasmonic Nanoparticles to Synergize Immunotherapeutic Fibroblast Activation Protein-Positive Cell Sensitization and Photothermal Therapy
    Small Science 5(2025)8, 2500099 (10.1002/smsc.202500099)
  • Lauwens, L.; Ribeiro, M.; Zegers, C. et al.
    Systematic review of MRI alterations in the brain following proton and photon radiation therapy: Towards a uniform European Particle Therapy Network (EPTN) definition
    Radiotherapy and Oncology 208(2025), 110936 (10.1016/j.radonc.2025.110936)
  • Kieslich, A. M.; Schellhammer, S.; Zwanenburg, A. et al.
    Machine-learning-based integration of temporal and spectral prompt gamma-ray information for proton range verification
    Physics and Imaging in Radiation Oncology 35(2025), 100788 (10.1016/j.phro.2025.100788)
  • Tran, L.; Oancea, C.; Kodaira, S. et al.
    Review of solid-state detectors for out-of-field dosimetry and microdosimetry in particle therapy
    Radiation Measurements 182(2025), 107386 (10.1016/j.radmeas.2025.107386)
  • Oancea, C.; Šolc, J.; Granja, C. et al.
    Radiation measurements using Timepix3 with silicon sensor and bare chip in proton beams for FLASH radiotherapy
    Journal of Instrumentation 20(2025), C04030 (10.1088/1748-0221/20/04/C04030)
  • Kaur, S.; Wenzel, B.; Oehme, R. et al.
    The hydrogenation side-reaction in copper-mediated radiofluorination
    EJNMMI Radiopharmacy and Chemistry 10(2025), 60 (10.1186/s41181-025-00384-1)
  • Krutzek, F.; Donat, C.; Stadlbauer, S.
    Structure–Activity Relationship of 18F-Labeled PD-L1-Targeting Small Molecule Ligands: Impact of Radiolabeling Strategy on Affinity and In Vivo Performance
    EJNMMI Radiopharmacy and Chemistry 10(2025), 33 (10.1186/s41181-025-00359-2)
  • Blei, M. K.; Hajduová, K.; Nový, Z. et al.
    Präklinische Bewertung von 203/212Pb-markierten mcp-PSMA-Liganden für die Bildgebung und Therapie von Prostatakrebs und PSMA-positiven Krebszellen
    Nuklearmedizin 64(2025), 76-77 (10.1055/s-0045-1804370)
  • Belke, L.; Blei, M. K.; Kopka, K. et al.
    Proof-of-Concept-Studie zur One-Pot Synthese zur simultanen Radiomarkierung und Verknüpfung des Chelators macropa mit dem PSMA-Liganden via Click-Reaktion
    Nuklearmedizin 64(2025), 75 (10.1055/s-0045-1804366)
  • Blei, M. K.; Ullrich, M.; Brühlmann, S. A. et al.
    Lanthan-133 als diagnostisches Gegenstück zu Actinium-225 in einer Kleintier-PET-Studie mit mcp-PSMA Liganden
    Nuklearmedizin 64(2025), 73 (10.1055/s-0045-1804359)
  • Mamat, C.; Weber, T.; Kreller, M. et al.
    Synthese von Diazabicyclononanen als Markierungsbausteine zur kupferfreien Click-Radiomarkierung mit Quecksilber-197(m)
    Nuklearmedizin 64(2025), 53 (10.1055/s-0045-1804302)
  • Ho, F.; Swart, R.; Boersma, L. et al.
    The road to successful implementation of innovation in radiotherapy: A research-based implementation protocol
    Radiotherapy and Oncology 207(2025), 110874 (10.1016/j.radonc.2025.110874)
  • Weiß, A.; Löck, S.; Xu, T. et al.
    Prediction for cardiac and pulmonary toxicity in a multicentric cohort of advanced stage NSCLC patients using sub-regions of the heart
    Clinical and Translational Radiation Oncology 53(2025), 100952
  • Jutrzenka-Trzebiatowski, A.; Gupte, R.; Daglar, C. et al.
    CliniMACS Prodigy manufacturing of switchable, AND-gate CAR T cells
    International Journal of Molecular Sciences 26(2025)11, 5024 (10.3390/ijms26115024)
  • Ueberham, L.; Kazimir, A.; Deuther-Conrad, W. et al.
    Development of Carborane-Based Benzothiazole Analogues as Cannabinoid Receptor Type 2 (CB2R) Ligands
    ACS Omega 10(2025)33, 38264-38271 (10.1021/acsomega.5c06508)
  • Trommer, J.; Ullrich, M.; Reissig, F. et al.
    It’s a match: Use of the radionuclide theranostic pair 133La/225Ac for the radiopharmacological characterization of EGFR-targeted single-domain antibodies
    European Journal of Nuclear Medicine and Molecular Imaging 10(2025), 31 (10.1186/s41181-025-00354-7)
  • Anh Nguyen-Le, T.; Cela, I.; Feldmann, A. et al.
    Label-free FET based biosensor for detection of engineered CAR T-cells at single cell resolution
    Advanced Sensor Research 4(2025)9, e00029 (10.1002/adsr.202500029)
  • Garrett Fernandes, M.; Bussink, J.; Wijsman, R. et al.
    Association between dose to cardiac structures and overall survival: A multivariable analysis in a large, multi-institutional database of stage III NSCLC patients with external validation
    Radiotherapy and Oncology 206(2025), 110821 (10.1016/j.radonc.2025.110821)
  • Ueberham, L.; Schädlich, J.; Schramke, K. et al.
    Carborane-Based Analogs of Celecoxib and Flurbiprofen, their COX Inhibition Potential, and COX Selectivity Index
    ChemMedChem 20(2025), e202500166 (10.1002/cmdc.202500166)
  • Selg, C.; Schuster, R.; Kazimir, A. et al.
    Advances in Diclofenac Derivatives: Exploring Carborane-Substituted N-Methyl and Nitrile Analogs for Anti-Cancer Therapy
    ChemMedChem 20(2025), e202500084 (10.1002/cmdc.202500084)
  • Zhao, X.; Schröder, T. A.; Heubner, L. et al.
    In vivo real-time monitoring of tissue perfusion via L-lactate levels in interstitial fluid: An innovative and portable microfluidic device trial using a pig model
    International Journal of Surgery 112(2026)2, 2623-2635 (10.1097/JS9.0000000000003263)
  • Boretti, V.; Horst, F. E.; Sennhenn, K. et al.
    Biological Impact of Target Fragments from 10 MeV - 20 GeV Proton Beams: Relevance to Proton Therapy and Space Radiation Protection
    Radiation Research 205(2025)4, 429-445 (10.1667/RADE-25-00060.1)
  • Sritharan, J.; Zeng, V.; Petr, J. et al.
    Cerebral Perfusion Differences in the Visual Cortex and Fusiform Subregions Across the Psychosis Spectrum
    Frontiers in Psychiatry 16(2025), 1566184 (10.3389/fpsyt.2025.1566184)
  • Horst, F. E.; Bodenstein, E.; Baumann, M. et al.
    The research beamlines at the Dresden proton therapy facility: available infrastructure and experimental capabilities
    Frontiers in Oncology 15(2025), 1594973 (10.3389/fonc.2025.1594973)
  • Daglar, C.; von Jutrzenka-Trzebiatowski, A.; Arndt, C. et al.
    Development of an ACE2-based Novel Recombinant Antibody Construct for the Therapy of SARS-CoV-2 Via Immune Cell Recruitment
    Human Gene Therapy (2025) (10.1089/hum.2025.38790.abstract)
  • Janićijević, Ž.; Baraban, L.
    Integration Strategies and Formats in Field-Effect Transistor Chemo- and Biosensors: A Critical Review
    ACS Sensors 10(2025)4, 2431-2452 (10.1021/acssensors.4c03633)
  • Gorodetska, I.; Lukiyanchuk, V.; Gawin, M. et al.
    Blood-based detection of MMP11 as a marker of prostate cancer progression regulated by the ALDH1A1-TGF-β1 signaling mechanism
    Journal of Experimental & Clinical Cancer Research 44(2025)1, 105 (10.1186/s13046-025-03299-6)
  • Kaur, S.; Dukic-Stefanovic, S.; Deuther-Conrad, W. et al.
    From inhibitors to PET: SAR-based development of [18F]SK60 for mIDH1 imaging
    Journal of Medicinal Chemistry 68(2025)13, 13750-13771 (10.1021/acs.jmedchem.5c00584)
  • Batool, A.; Kopp, I.; Kubeil, M. et al.
    Targeted bismuth-based materials for cancer
    Dalton Transactions 54(2025), 5614-5639 (10.1039/D5DT00163C)
  • Brandt, F.; Ullrich, M.; Laube, M. et al.
    Deciphering the tumor uptake of heterobivalent (SST₂/albumin) [⁶⁴Cu]Cu-NODAGA-cLAB-TATEs
    Journal of Medicinal Chemistry 68(2025)11, 12029-12046 (10.1021/acs.jmedchem.5c00890)
  • Streller, M.; Michlikova, S.; Ciecior, W. et al.
    Image segmentation of treated and untreated tumor spheroids by fully convolutional networks
    GigaScience 14(2025), giaf027 (10.1093/gigascience/giaf027)
  • Deuther-Conrad, W.; Schepmann, D.; Iriepa, I. et al.
    2-{N-[ω-(1-Benzylpiperidin-4-yl)alkyl]amino}-6-[(prop-2-yn-1-yl)amino]pyridine-3,5-dicarbonitriles Showing High Affinity for σ1/2 Receptors
    International Journal of Molecular Sciences 26(2025)3, 1266 (10.3390/ijms26031266)
  • Idris, R. M.; Al-Hroub, H.; Schmies, C. C. et al.
    Design, development and evaluation of a radiotracer for ecto-5’-nucleotidase (CD73) – a versatile research tool and diagnostic agent for personalized medicine
    Biomedicine and Pharmacotherapy 188(2025), 118115 (10.1016/j.biopha.2025.118115)
  • Neuber, C.; Niedenzu, L.; Schulze, S. et al.
    Exploring a nitric oxide-releasing celecoxib derivative as a potential modulator of bone healing: insights from ex vivo and in vivo imaging experiments
    International Journal of Molecular Sciences 26(2025), 2582 (10.3390/ijms26062582)
  • Büttner, M.; Melton, P.; Fietkau, R. et al.
    Successful implementation of online educational lectures of the German Society for Radiation Oncology (DEGRO)
    Strahlentherapie und Onkologie 200(2024), 151-158 (10.1007/s00066-023-02162-x)
  • Linge, A.; Patil, S.; Grosser, M. et al.
    The value of subcutaneous xenografts for individualised radiotherapy in HNSCC: Robust gene signature correlates with radiotherapy outcome in patients and xenografts
    Radiotherapy and Oncology 191(2024), 110055 (10.1016/j.radonc.2023.110055)
  • Baumann, M.; Bacchus, C.; Aznar, M. et al.
    Clinical research for global needs of radiation oncology
    Radiotherapy and Oncology 190(2024), 110076 (10.1016/j.radonc.2023.110076)
  • Kirchner, J.; Plesca, I.; Rothe, R. et al.
    Type I conventional dendritic cells and CD8(+) T cells predict favorable clinical outcome of head and neck squamous cell carcinoma patients
    Frontiers in Immunology 15(2024), 1414298 (10.3389/fimmu.2024.1414298)
  • Baugh, J. N.; Veldhuijzen van Zanten, S.; Fiocco, M. et al.
    Treatment-related survival patterns in diffuse intrinsic pontine glioma using a historical cohort: A report from the European Society for Pediatric Oncology DIPG/DMG Registry
    Neuro-Oncology 6(2024), vdae155 (10.1093/noajnl/vdae155)
  • Knäusl, B.; Belotti, G.; Bertholet, J. et al.
    A review of the clinical introduction of 4D particle therapy research concepts
    Physics and Imaging in Radiation Oncology 29(2024), 100535 (10.1016/j.phro.2024.100535)
  • Mortensen, H. R.; Populaire, P.; Hoffmann, L. et al.
    Proton versus photon therapy for esophageal cancer – A trimodality strategy
    Radiotherapy and Oncology 190(2024), 109980 (10.1016/j.radonc.2023.109980)
  • Trnkova, P.; Dasu, A.; Placidi, L. et al.
    Patterns of practice of image guided particle therapy for cranio-spinal irradiation: A site specific multi-institutional survey of European Particle Therapy Network
    Physica Medica, European Journal of Medical Physics 123(2024), 103407 (10.1016/j.ejmp.2024.103407)
  • Trnkova, P.; Dasu, A.; Placidi, L. et al.
    Patterns of practice of image guided particle therapy for cranio-spinal irradiation: A site specific multi-institutional survey of European Particle Therapy Network
    Physica Medica, European Journal of Medical Physics 140(2025), 105211 (10.1016/j.ejmp.2025.105211)
  • Philchenkov, A.; Dubrovska, A.
    Cancer Stem Cells as a Therapeutic Target: Current Clinical Development and Future Prospective
    Stem Cells 42(2024)3, 173-199 (10.1093/stmcls/sxad092)
  • Mehralivand, S.; Thomas, C.; Puhr, M. et al.
    New advances of the androgen receptor in prostate cancer: report from the 1st International Androgen Receptor Symposium
    Journal of Translational Medicine 22(2024), 71 (10.1186/s12967-024-04878-5)
  • Beier, A.-M. K.; Ebersbach, C.; Siciliano, T. et al.
    Targeting the glutamine metabolism to suppress cell proliferation in mesenchymal docetaxel-resistant prostate cancer
    Oncogene 43(2024), 2038 (10.1038/s41388-024-03059-4)
  • Subbarayan, K.; Al-Samadi, A.; Schäfer, H. et al.
    Altered ACE2 and interferon landscape in the COVID-19 microenvironment correlate with the anti-PD-1 response in solid tumors
    Cellular and Molecular Life Sciences 81(2024)473 (10.1007/s00018-024-05520-9)
  • Nguyen-Le, T.-A.; Neuber, C.; Cela, I. et al.
    Towards Personalized Immunotherapeutic Drug Monitoring with Multiplexed Extended Gate FET Biosensors
    Small Science 5(2025)5, 2400515 (10.1002/smsc.202400515)
  • Helberta, H.; Deuther-Conrad, W.; de Haan, M. et al.
    Synthesis and in vitro evaluation of spirobenzovesamicols as potential 11C-PET tracer alternatives to [18F]FEOBV for vesicular acetylcholine transporter (VAChT) imaging
    European Journal of Nuclear Medicine and Molecular Imaging 10(2025)1, 7 (10.1186/s41181-025-00327-w)
  • Mehnert, E.; Möller, F.; Hofbauer, C. et al.
    Palliative care of proximal femur metastatic disease and osteolytic lesions: results following surgical and radiation treatment
    BMC Cancer 24(2024), 1431 (10.1186/s12885-024-13170-0)
  • Isaksson, L.; Mastroleo, F.; Vincini, M. et al.
    The emerging role of Artificial Intelligence in proton therapy: a review
    Critical Reviews in Oncology / Hematology 204(2024), 104485 (10.1016/j.critrevonc.2024.104485)
  • de Mendoza, A. M.; Michlikova, S.; Castro, P. S. et al.
    Generalized, sublethal damage-based mathematical approach for improved modeling of clonogenic survival curve flattening upon hyperthermia, radiotherapy, and beyond
    Physics in Medicine and Biology 70(2025), 025022 (10.1088/1361-6560/ada680)
  • Burger, E.-M.; Hauser, S.; Donat, C. et al.
    Investigation of a GPC-3-addressing peptide as potential radioligand for PET imaging of HCC
    Nuklearmedizin 63(2024)2, 154 (10.1055/s-0044-1782473)
  • Schädlich, J.; Ullrich, M.; Haase-Kohn, C. et al.
    Radioiodinated closo-dicarbadodecaborane(12)-based cyclooxygenase-2/5-lipoxygenase inhibitors
    EJNMMI Radiopharmacy and Chemistry 9(2024)Suppl 1, OP14 (10.1186/S41181-024-00294-8)
  • Trommer, J.; Kučka, J.; Vercellino, S. et al.
    Radiolabeling of M13 bacteriophages for in vivo imaging
    EJNMMI Radiopharmacy and Chemistry 9(2024), 65 (10.1186/s41181-024-00294-8)
  • Batool, A.; Duffin, R. N.; Burke, K. et al.
    Bismuth Oxide Nanorings: A Potential Material for Hyperthermia-Based Tumor Therapy
    ACS Applied Nano Materials 8(2025)1, 622-630 (10.1021/acsanm.4c05976)
  • Jarutyte, L.; Petr, J.; Turner, N. et al.
    Advantages and challenges of using arterial spin labelling MRI to monitor cerebral blood flow in multi-centre clinical trials of neurodegenerative disease: Experience from the RADAR study
    Cerebral Circulation, Cognition and Behavior 8(2025), 100376 (10.1016/j.cccb.2024.100376)
  • Höffmann, L.; Blei, M. K.; Reissig, F. et al.
    Preparation of macrobicyclic cryptands for radiometal complexation
    Journal of Labelled Compounds and Radiopharmaceuticals 68(2025)3, e4136 (10.1002/jlcr.4136)
  • Dijsselhof, M. B. J.; Moore, C.; Amiri, S. et al.
    Multi-cohort, multi-sequence harmonisation for cerebrovascular brain age
    Imaging Neuroscience 3(2025), IMAG.a.964 (10.1162/IMAG.a.964)
  • Eitler, J.; Rackwitz, W.; Wotschel, N. et al.
    CAR-mediated targeting of NK cells overcomes tumor immune escape caused by ICAM-1 downregulation
    Journal for ImmunoTherapy of Cancer 12(2024), e008155 (10.1136/jitc-2023-008155)
  • Ahmed, M.; Beyreuther, E.; Gantz, S. et al.
    Design and dosimetric characterization of a transportable proton minibeam collimation system
    Frontiers in Oncology 14(2024), 1473625 (10.3389/fonc.2024.1473625)
  • Urbanovský, P.; David, T.; Hlinová, V. et al.
    Cross-bridged cyclam derivatives with bis(phosphinate) and phosphinate-phosphonate pendant arms (cb-BPC) as chelators for copper radioisotopes
    Organic & Biomolecular Chemistry 23(2025), 699-720 (10.1039/D4OB01473A)
  • Prysiazhniuk, Y.; Kala, D.; Holubová, Z. et al.
    Doporučení pro použití Arterial Spin Labeling v rámci klinického neurozobrazování
    Czech and Slovak Neurology and Neurosurgery 88(2025)1, 22-31 (10.48095/cccsnn202522)
  • Peng, X.; Janićijević, Ž.; Rodrigues Loureiro, L. R. et al.
    Microphysiological Solid Tumor Models in Hydrogel Beads for CAR T Cell Immunotherapy Evaluation
    Advanced Science 12(2025)41, e08267 (10.1002/advs.202508267)
  • Selg, C.; Gordić, V.; Krajnović, T. et al.
    Re-design and evaluation of diclofenac-based carborane-substituted prodrugs and their anti-cancer potential
    Scientific Reports 14(2024), 30488 (10.1038/s41598-024-81414-x)
  • Markl, A. M.; Nieder, D.; Sandoval Bojorquez, D. I. et al.
    Heterogeneity of tumor biophysical properties and their potential role as prognostic markers.
    Cancer Heterogeneity and Plasticity 1(2024)2, 0011 (10.47248/chp2401020011)
  • Tinganelli, W.; Puspitasari-Kokko, A.; Sokol, O. et al.
    FLASH Bragg-peak irradiation with a therapeutic carbon ion beam: first in vivo results
    International Journal of Radiation Oncology Biology Physics 121(2025)5, 1282-1292 (10.1016/j.ijrobp.2024.11.089)
  • May, H. G.; Tsikonofilos, K.; Donat, C. et al.
    EEG hyperexcitability and hyperconnectivity linked to GABAergic inhibitory interneuron loss following traumatic brain injury
    Brain Communications 6(2024)6, fcae385 (10.1093/braincomms/fcae385)
  • Clegg, J.; Curvello, R.; Gabrielyan, A. et al.
    Tailoring metabolic activity assays for tumour-engineered 3D models
    Biomaterials Advances 167(2025), 214116 (10.1016/j.bioadv.2024.214116)
  • Liolios, C.; Bouziotis, D.; Sihver, W. et al.
    Synthesis and Preclinical Evaluation of a Bispecific PSMA-617/RM2 Heterodimer Targeting Prostate Cancer
    ACS Medicinal Chemistry Letters 15(2024)11, 1970-1978 (10.1021/acsmedchemlett.4c00324)
  • Sokol, O.; Frederiksen, A. T.; Sitarz, M. et al.
    In vitro measurement of proton RBE: a multi-centric comparison using a harmonized setup
    Clinical and Translational Radiation Oncology 53(2025), 100978 (10.1016/j.ctro.2025.100978)
  • Nenoff, L.; Trnková, P.; Bertini, F. et al.
    SWOT Analysis of Online Adaptive Particle Therapy: Results from the EPTN adaptive task group
    Radiotherapy and Oncology 206(2025)Suppl. 1, S3168 (10.1016/S0167-8140(25)01599-3)
  • Berthold, J.; Nenoff, L.; Bertschi, S. et al.
    First-in-human 4D treatment verification with a prompt-gamma imaging slit-camera for a pancreatic-cancer patient in proton therapy
    Radiotherapy and Oncology 206(2025)Suppl. 1, S3117 (10.1016/S0167-8140(25)00662-0)
  • Doctor, A.; Schädlich, J.; Hauser, S. et al.
    Investigation of the Putative Relationship Between Copper Transport and the Anticancer Activity of Cisplatin in Ductal Pancreatic Adenocarcinoma
    Cells 14(2025), 1489 (10.3390/cells14191489)
  • Lis, C.; Ludwig, F.-A.; Fischer, S. et al.
    Development of [99mTc]TcO-ABX474: Design, Synthesis and biological Evaluation of PSMA-binding Technetium-99m radioligands for SPECT Imaging of Prostate Cancer
    Journal of Medicinal Chemistry 68(2025)7, 7213-7231 (10.1021/acs.jmedchem.4c02767)
  • Pietzsch, J.; Toussaint, M.; Donat, C. et al.
    Exploring the role of peripheral macrophages in glioma progression: the metabolic significance of cyclooxygenase-2 (COX-2)
    International Journal of Molecular Sciences 26(2025), 6198 (10.3390/ijms26136198)
  • Leikina, E.; Whitlock, J. M.; Melikov, K. et al.
    Formation of multinucleated osteoclasts depends on an oxidized species of cell surface-associated La protein
    eLife 13(2024)RP98665 (10.7554/eLife.98665)
  • Braune, A.; Hosch, R.; Kersting, D. et al.
    External phantom-based validation of a deep-learning network trained for upscaling of digital low count PET data
    EJNMMI Physics 12(2025)1, 38 (10.1186/s40658-025-00745-4)
  • Hausmann, P.; Zschaeck, S.; Furth, C. et al.
    Tumor asphericity on FDG-PET images is an independent prognostic parameter and improves risk stratification in head and neck squamous cell carcinoma patients
    Journal of Nuclear Medicine 66(2025)5, 686-691 (10.2967/jnumed.124.268972)
  • Zschaeck, S.; Hajiyianni, M.; Hausmann, P. et al.
    Total lesion glycolysis of primary tumor and lymphnodes is a strong predictor for development of distant metastases in oropharyngeal carcinoma patients with independent validation in automatically delineated lesions
    Cancer Imaging 25(2025)1, 18 (10.1186/s40644-025-00836-6)
  • Lemm, S.; Gebhardt, M.; Groß, T. et al.
    Radioresistant Mouse Pheochromocytoma Cell Lines
    Frontiers in Oncology 15(2025), 1517132 (10.3389/fonc.2025.1517132)
  • Novy, Z.; Hajduova, K.; Petrik, M. et al.
    Preclinical assessment of enhanced blood retention and tumor uptake PSMA-targeting 225Ac-labeled radioconjugates
    EJNMMI Radiopharmacy and Chemistry 9(2024), OP30 (10.1186/s41181-024-00294-8)
  • Blei, M. K.; Drobot, B.; Stadlbauer, S. et al.
    Synthesis, stability determination and radiolabeling of new diazabenzene-based azamacrocycles with barium-131, actinium-225, lanthanum-133, and lead-212
    EJNMMI Radiopharmacy and Chemistry 9(2024), OP15 (10.1186/s41181-024-00294-8)
  • Palkowitsch, M.; Kaufmann, L.-M.; Hennings, F. et al.
    Variable-RBE-induced NTCP predictions for various side-effects following proton therapy for brain tumors – Identification of high-risk patients and risk mitigation
    Radiotherapy and Oncology 202(2025), 110590 (10.1016/j.radonc.2024.110590)
  • Vaxevanis, C.; Bachmann, M.; Seliger, B.
    Immune modulatory microRNAs in tumors, their clinical relevance in diagnosis and therapy
    Journal for ImmunoTherapy of Cancer 12(2024), e009774 (10.1136/jitc-2024-009774)
  • Gambetta, V.; Pieta, V.; Berthold, J. et al.
    Partial adaptation for online-adaptive proton therapy triggered by during-delivery treatment verification: Feasibility study on prostate cancer treatments
    Physics and Imaging in Radiation Oncology 34(2025), 100755 (10.1016/j.phro.2025.100755)
  • Bertschi, S.; Stützer, K.; Berthold, J. et al.
    Feasibility of prompt gamma verification for cone-beam CT-based online adaptive proton therapy
    Medical Physics 34(2025), 100778 (10.1016/j.phro.2025.100778)
  • Ahmed, A.; Alegret, N.; Almeida, B. et al.
    Interfacing with the Brain: How Nanotechnology Can Contribute
    ACS Nano 19(2025), 10630-10717 (10.1021/acsnano.4c10525)
  • Boutier, H.; Rodrigues Loureiro, L. R.; Hoffmann, L. et al.
    The UniCAR system – From Target Module Engineering to Diagnosis & Treatment of FAP+ tumours
    Human Gene Therapy (2025) (10.1089/hum.2025.38790.abstract)
  • Vehlow, A.; Lange, I.; Lagies, S. et al.
    Cytotoxic and Radiosensitizing Effects of European and African Propolis in 3D Lung Carcinoma Cell Cultures
    Anticancer Research 44(2024)11, 4801-4811 (10.21873/anticanres.17306)
  • Besso, M. J.; Bitto, V.; Koi, L. et al.
    Transcriptomic and epigenetic landscape of nimorazole-enhanced radiochemotherapy in head and neck cancer
    Radiotherapy and Oncology 199(2024), 110348 (10.1016/j.radonc.2024.110348)
  • Gündel, D.; Teodoro, R.; Ludwig, F.-A. et al.
    Development and Evaluation of Deuterated [18F]JHU94620 Isotopologues for the Non-invasive Assessment of the Cannabinoid type 2 Receptor in Brain
    EJNMMI Radiopharmacy and Chemistry 9(2024), 91 (10.1186/s41181-024-00319-2)
  • Peters, N.; Taasti, V. T.; Ackermann, B. et al.
    Response to “Letter regarding Consensus guide on CT-based prediction of stopping-power ratio using a Hounsfield look-up table for proton therapy”
    Radiotherapy and Oncology 190(2024), 109961 (10.1016/j.radonc.2023.109961)
  • Brunner, J.; Langgartner, L.; Danhel, H. et al.
    Dosimetric characteristics of 3D-printed and epoxy-based materials for particle therapy phantoms
    Frontiers in Physics 12(2024), 1323788 (10.3389/fphy.2024.1323788)
  • Crespo, E.; Rodrigues Loureiro, L. R.; Stammberger, A. et al.
    RevCAR-mediated T-Cell Response against PD-L1-expressing Cells Turns Suppression into Activation
    npj Precision Oncology 9(2025), 42 (10.1038/s41698-025-00828-6)
  • Matesanz-Sánchez, R.; Classen, S.; Siniukc, K. et al.
    Precise metabolomics identifies glycolysis-related pyruvate kinase M activity as regulator of the S-phase-specific radiation response in triple-negative breast cancer cells
    Cell Communication and Signaling 24(2026), 216 (10.1186/s12964-026-02803-5)
  • Nazary, H.; Metternich, M.; Schumacher, D. et al.
    Towards ion stopping power experiments with the laser-driven LIGHT beamline
    Journal of Plasma Physics 90(2024)3, 905900302 (10.1017/S0022377824000576)
  • Wolter, L. C.; Hennings, F.; Bokor, J. et al.
    Validity of one-time phantomless patient-specific quality assurance in proton therapy with regard to the reproducibility of beam delivery
    Medical Physics 52(2025)5, 3173-3182 (10.1002/mp.17637)
  • Scott, P.; Penuelas, I.; Rey, A. et al.
    Highlight selection of radiochemistry and radiopharmacy developments by editorial board
    EJNMMI Radiopharmacy and Chemistry 9(2024), 67 (10.1186/s41181-024-00296-6)
  • Metzger, G.; Bayerl, C.; Rogasch, J. et al.
    68Ga-labeled fibroblast activation protein inhibitor (FAPI) PET/CT for locally advanced or recurrent pancreatic cancer staging and restaging after chemoradiotherapy
    Theranostics 14(2024)11, 4184-4197 (10.7150/thno.95329)
  • Bela Andela, S.; Amthauer, H.; Furth, C. et al.
    Quantitative PSMA-PET parameters in localized prostate cancer: prognostic and potential predictive value
    Radiation Oncology 19(2024), 97 (10.1186/s13014-024-02483-w)
  • Oborn, B. M.; Semioshkina, E.; van der Kraaij, E. et al.
    Simulation and experimental benchmarking of a proton pencil beam scanning nozzle for development of MRI-guided proton therapy
    Medical Physics 51(2024)9, 6196-6205 (10.1002/mp.17279)
  • Padrela, B. E.; Slivka, M.; Sneve, M. H. et al.
    Blood-brain barrier water permeability across the adult lifespan: A multi-echo ASL study
    Neurobiology of Aging 147(2025), 176-186 (10.1016/j.neurobiolaging.2024.12.012)
  • Schott, M.; Vehlow, A.; Benka, M. et al.
    Aqueous extracts from Dioscorea sansibarensis Pax show cytotoxic and radiosensitizing potential in 3D growing HPV-negative and HPV-positive human head and neck squamous cell carcinoma models
    Biomedicine and Pharmacotherapy 179(2024), 117305 (10.1016/j.biopha.2024.117305)
  • Doctor, A.; Laube, M.; Meister, S. et al.
    Combined PET radiotracer approach reveals insights into stro-mal cell-induced metabolic changes in pancreatic cancer in vitro and in vivo
    Cancers 16(2024), 3393 (10.3390/cancers16193393)
  • Azizova, A.; Wamelink, I. J. H. G.; Prysiazhniuk, Y. et al.
    Human Performance in Predicting Enhancement Quality of Gliomas Using Gadolinium-Free MRI Sequences
    Journal of Neuroimaging 34(2024)6, 673-693 (10.1111/jon.13233)
  • Zegers, C.; Swinnen, A.; Roumen, C. et al.
    High precision stereotactic irradiation for focal drug-resistant epilepsy versus standard treatment: a randomized waitlist-controlled trial (the PRECISION-trial)
    Trials 25(2024), 334 (10.1186/s13063-024-08168-9)
  • Witzmann, K.; Raschke, F.; Wesemann, T. et al.
    Diffusion decrease in normal-appearing white matter structures following photon or proton irradiation indicates differences in regional radiosensitivity
    Radiotherapy and Oncology 199(2024), 110459 (10.1016/j.radonc.2024.110459)
  • Shahzadi, I.; Seidlitz, A.; Beuthien-Baumann, B. et al.
    Radiomics for the detection of residual tumour status after surgery and patient outcome prediction after chemoradiotherapy in newly diagnosed glioblastoma based on [11C] methionine PET and T1c-w MRI
    Scientific Reports 14(2024), 4576 (10.1038/s41598-024-55092-8)
  • Igbo, B. T.; Jentsch, C.; Linge, A. et al.
    Correlation of microscopic tumor extension with tumor microenvironment in esophageal cancer patients
    Strahlentherapie und Onkologie 200(2024), 595-604 (10.1007/s00066-024-02234-6)
  • Grau, C.; Dasu, A.; Troost, E. G. C. et al.
    Towards a European prospective data registry for particle therapy
    Radiotherapy and Oncology 196(2024), 110293 (10.1016/j.radonc.2024.110293)
  • Erb, H.; Polishchuk, N.; Stasyk, O. et al.
    Glutamine metabolism and prostate cancer
    Cancers 16(2024)16, 2871 (10.3390/cancers16162871)
  • Sihver, W.; Walther, M.; Ullrich, M. et al.
    Cyclohexanediamine triazole (CHDT)-functionalization enables labeling of target molecules with Al18F / 68Ga / 111In
    Bioconjugate Chemistry 35(2024)9, 1402-1416 (10.1021/acs.bioconjchem.4c00313)
  • Krönke, T.; Kopka, K.; Mamat, C.
    Enhancing the radionuclide theranostic concept through the radiohybrid approach
    RSC Medicinal Chemistry 16(2025), 1856-1864 (10.1039/d4md00591k)
  • Rothe, R.; Xu, Y.; Wodtke, J. et al.
    Programmable Release of Chemotherapeutics from Ferrocene-based Injectable Hydrogels Slows Melanoma Growth
    Advanced Healthcare Materials 13(2024)27, 2400265 (10.1002/adhm.202400265)
  • Ullrich, M.; Wodtke, R.; Brandt, F. et al.
    The heterobivalent (SSTR2/albumin) radioligand [67Cu]cCu-NODAGA-cLAB4-TATE enables efficient somatostatin receptor radionuclide theranostics
    Theranostics 14(2024)14, 5371-5387 (10.7150/thno.100091)
  • Samarzija, I.; Lukiyanchuk, V.; Lončarić, M. et al.
    The extracellular matrix component Perlecan/HSPG2 regulates radioresistance in prostate cancer cells
    Frontiers in Cell and Developmental Biology 12(2024), 1452463 (10.3389/fcell.2024.1452463)
  • Maus, J.; Nikulin, P.; Hofheinz, F. et al.
    Deep learning based bilateral filtering for edge-preserving denoising of respiratory-gated PET
    EJNMMI Physics 11(2024), 58 (10.1186/s40658-024-00661-z)
  • Azizova, A.; Prysiazhniuk, Y.; Wamelink, I. J. H. G. et al.
    Preoperative Prediction of Diffuse Glioma Type and Grade in Adults: a Gadolinium-Free MRI-Based Decision Tree
    European Radiology 35(2025), 1242-1254 (10.1007/s00330-024-11140-5)
  • Marie Benko, L.; Misko, V. R.; Baraban, L. et al.
    Janus Particles in Acoustofluidic Setup: The Interplay between Self-Propulsion and Acoustic Trapping
    Micro 4(2024)1, 185-195 (10.3390/micro4010013)
  • Sonam, S.; Jelača, S.; Laube, M. et al.
    Carborane Conjugates with Ibuprofen, Fenoprofen and Flurbiprofen: Synthesis, Characterization, COX Inhibition Potential and In Vitro Activity
    ChemMedChem 20(2025), e202400018 (10.1002/cmdc.202400018)
  • Ratliff, H. N.; Kögler, T.; Pausch, G. et al.
    The Backscatter Gating method for time, energy, and position resolution characterization of long form factor organic scintillators
    Journal of Instrumentation 19(2024)07, P07002 (10.1088/1748-0221/19/07/P07002)
  • Wang, J.; Wang, T.; Mou, T. et al.
    Novel 18F-labeled benzimidazolone-based radioligands as highly selective sigma-2 receptor probes for tumor imaging
    Journal of Medicinal Chemistry 67(2024)19, 17392-17406 (10.1021/acs.jmedchem.4c01315)
  • Schneider, M.; Schilz, J.; Schürer, M. et al.
    SAPPHIRE - Establishment of Small Animal Proton and PHoton Image-guided Radiation Experiments
    Physics in Medicine and Biology 69(2024)97, 095020 (10.1088/1361-6560/ad3887)
  • Rodrigues Loureiro, L. R.; Pike, S.; Wuest, M. et al.
    Tackling prostate cancer with theranostic E5B9-bombesin target modules (TMs): from diagnostic imaging to treatment with UniCAR T-cells
    International Journal of Molecular Sciences 26(2025)6, 2686 (10.3390/ijms26062686)
  • Kaushik, S.; Stützer, K.; Ödén, J. et al.
    Adaptive intensity modulated proton therapy using 4D robust planning: a proof-of-concept for the application of dose mimicking approach
    Physics in Medicine and Biology 69(2024)18, 185010 (10.1088/1361-6560/ad75e0)
  • Dijsselhof, M. B. J.; Holtrop, J.; James, S.-N. et al.
    Associations of life-course cardiovascular risk factors with late-life cerebral haemodynamics
    Journal of Cerebral Blood Flow and Metabolism 45(2025)4, 765-778 (10.1177/0271678X241301261)
  • Samimi, R.; Kamali-Asl, A.; Ahmadyar, Y. et al.
    Dual time-point [18F]FDG PET imaging for quantification of metabolic uptake rate: Evaluation of a simple, clinically feasible method
    Physica Medica, European Journal of Medical Physics 121(2024), 103336 (10.1016/j.ejmp.2024.103336)
  • Brühlmann, S. A.; Walther, M.; Blei, M. K. et al.
    Scalability Study on [133La]LaCl3 Production with a Focus on Potential Clinical Applications
    EJNMMI Radiopharmacy and Chemistry 9(2024)1, 60 (10.1186/s41181-024-00292-w)
  • Makarevich, K.; Schellhammer, S.; Pausch, G. et al.
    Proton bunch monitors for the clinical translation of prompt gamma-ray timing
    Physics in Medicine and Biology 69(2024), 225013 (10.1088/1361-6560/ad8c96)
  • Schieferecke, J.; Hoffmann, A. L.; Pawelke, J.
    MR imaging of proton beam-induced oxygen depletion
    Medical Physics 52(2025)4, 2454-2464 (10.1002/mp.17622)
  • Hueso-González, F.; Berthold, J.; Wohlfahrt, P. et al.
    Inter-center comparison of proton range verification prototypes with an anthropomorphic head phantom
    Physics in Medicine and Biology 69(2024)22, 225010 (10.1088/1361-6560/ad8856)
  • Schniewind, I.; José Besso, M.; Klicker, S. et al.
    Epigenetic Targeting to Overcome Radioresistance in Head and Neck Cancer
    Cancers 16(2024), 730 (10.3390/cancers16040730)
  • Boutier, H.; Rodrigues Loureiro, L. R.; Hoffmann, L. et al.
    UniCAR T-cell potency – A matter of affinity between Adaptor Molecules and Adaptor CAR T-cells?
    International Journal of Molecular Sciences 25(2024)13, 7242 (10.3390/ijms25137242)
  • Blei, M. K.; Drobot, B.; Stadlbauer, S. et al.
    Synthese, Stabilitätsbestimmung und Radiomarkierung neuer Pym-Azamakrozyklen mit Barium-131, Actinium-225, Lanthan-133, und Blei-212
    Nuklearmedizin 63(2024), 91 (10.1055/s-0044-1782286)
  • Krönke, T.; Zarschler, K.; Reissig, F. et al.
    Iod-123-basierte Radiohybridkonjugate als diagnostisches Match zur zielgerichteten Alphatherapie mit Actinium-225
    Nuklearmedizin 63(2024), 111 (10.1055/s-0044-1782344)
  • Tee, M.; Padrela, B.; Dupeyron, M. et al.
    Associations between Potential Risk Factors and Blood-brain Barrier Water Permeability in Middle-aged and Older Adults
    Journal of Alzheimer's Disease 104(2025)1, 95-105 (10.1177/13872877251314138)
  • Wamelink, I.; Azizova, A.; Booth, T. et al.
    Rebuttal to the LET to be paired with RAD-24-0653, entitled Gadolinium Reduction in Brain Tumor Imaging: A Paradigm Shift in Diagnostic Strategies
    Radiology (2024) (10.1148/radiol.240653)
  • Starke, S.; Kieslich, A. M.; Palkowitsch, M. et al.
    A deep-learning-based surrogate model for Monte-Carlo simulations of the linear energy transfer in primary brain tumor patients treated with proton-beam radiotherapy
    Physics in Medicine and Biology 69(2024), 165034 (10.1088/1361-6560/ad64b7)
  • Prysiazhniuk, Y.; Server, A.; Leske, H. et al.
    Diffuse glioma molecular profiling with Arterial Spin Labeling and Dynamic Susceptibility Contrast perfusion MRI: a comparative study
    Neuro-Oncology Advances 6(2024)1, vdae113 (10.1093/noajnl/vdae113)
  • Padrela, B.; Mahroo, A.; Tee, M. et al.
    Developing blood-brain barrier arterial spin labelling as a non-invasive early biomarker of Alzheimer’s disease (DEBBIE-AD): a prospective observational multicohort study protocol
    BMJ Open 14(2024)3, e081635 (10.1136/bmjopen-2023-081635)
  • Kubeil, M.; Neuber, C.; Starke, M. et al.
    64Cu tumor labeling with hexadentate picolinic acid-based bispidine immunoconjugates
    Chemistry - A European Journal 30(2024), e202400366 (10.1002/chem.202400366)
  • Weber, T.; Krönke, T.; Köckerling, M. et al.
    Towards the Stable Binding of Mercury: Synthesis and Functionalization of Dibenzyldiazabicyclononane Scaffolds
    European Jounal of Organic Chemistry 27(2024)25, e202400258 (10.1002/ejoc.202400258)
  • Toyohara, J.; Vugts, D.; Kiß, O. et al.
    Highlight selection of radiochemistry and radiopharmacy developments by editorial board
    EJNMMI Radiopharmacy and Chemistry 9(2024), 42 (10.1186/s41181-024-00268-w)
  • Paschoal, A. M.; Woods, J. G.; Pinto, J. et al.
    Reproducibility of Arterial Spin Labeling Cerebral Blood Flow image processing: A Report of The ISMRM Open Science Initiative for Perfusion Imaging and the ASL MRI Challenge
    Magnetic Resonance in Medicine 92(2024), 836-852 (10.1002/mrm.30081)
  • Cegla, P.; Hofheinz, F.; Czepczyński, R. et al.
    Value of [18F] FDG PET/CT parameters of the primary tumor in assessing overall survival in NSCLC patients with cN1-cN3 lymph nodes involvement
    Reports of Practical Oncology and Radiotherapy 29(2024)1, 97-102 (10.5603/rpor.99360)
  • Abdelfatah Saleh Hassan, H. A.; Mitwasi, N.; Rodrigues Loureiro, L. R. et al.
    RevCAR-expressing immune effector cells for targeting of Fn14-positive glioblastoma
    Cancer Gene Therapy 31(2024), 1323-1334 (10.1038/s41417-024-00766-8)
  • Bigos, K.; Quiles, C.; Lunj, S. et al.
    Tumour response to hypoxia: understanding the hypoxic tumour microenvironment to improve treatment outcome in solid tumours
    Frontiers in Oncology 14(2024), 1331355 (10.3389/fonc.2024.1331355)
  • Mamat, C.; Köckerling, M.
    The crystal structure of (2-diphenylphosphanylphenyl) 2-[7-(dimethylamino)-2-oxochromen-4-yl]acetate, C31H26NO4P
    Zeitschrift für Kristallographie - New Crystal Structures 239(2024), 511 (10.1515/ncrs-2024-0065)
  • Maisonial-Besset, A.; Kryza, D.; Kopka, K. et al.
    Improved automated one-pot two-step radiosynthesis of (S)-[18F]FETrp, a radiotracer for PET imaging of indoleamine 2,3-dioxygenase 1 (IDO1)
    European Journal of Nuclear Medicine and Molecular Imaging 9(2024), 28 (10.1186/s41181-024-00256-0)
  • Peng, X.; Janićijević, Ž.; Lemm, S. et al.
    Impact of Viscosity on Human Hepatoma Spheroids in Soft Core-Shell Microcapsules
    Advanced Healthcare Materials 11(2024)13, 2302609 (10.1002/adhm.202302609)
  • Zhang, Y.; Trnkova, P.; Toshito, T. et al.
    A survey of practice patterns for real-time intrafractional motion-management in particle therapy
    Physics and Imaging in Radiation Oncology 26(2023), 100439 (10.1016/j.phro.2023.100439)
  • Trnkova, P.; Zhang, Y.; Toshito, T. et al.
    A survey of practice patterns for adaptive particle therapy for interfractional changes
    Physics and Imaging in Radiation Oncology 26(2023), 100442 (10.1016/j.phro.2023.100442)
  • Tawk, B.; Rein, K.; Schwager, C. et al.
    DNA-Methylome–Based Tumor Hypoxia Classifier Identifies HPV-Negative Head and Neck Cancer Patients at Risk for Locoregional Recurrence after Primary Radiochemotherapy
    Clinical Cancer Research 29(2023)16, 3051-3064 (10.1158/1078-0432.CCR-22-3790)
  • Peters, N.; Trier Taasti, V.; Ackermann, B. et al.
    Consensus guide on CT-based prediction of stopping-power ratio using a Hounsfield look-up table for proton therapy
    Radiotherapy and Oncology 184(2023), 109675 (10.1016/j.radonc.2023.109675)
  • Vrou Offersen, B.; Aznar, M. C.; Bacchus, C. et al.
    The role of ESTRO guidelines in achieving consistency and quality in clinical radiation oncology practice
    Radiotherapy and Oncology 179(2023), 109446 (10.1016/j.radonc.2022.109446)
  • Leichtle, F.; Betzler, A. C.; Eizenberger, C. et al.
    Influence of Bruton’s Tyrosine Kinase (BTK) on Epithelial–Mesenchymal Transition (EMT) Processes and Cancer Stem Cell (CSC) Enrichment in Head and Neck Squamous Cell Carcinoma (HNSCC)
    International Journal of Molecular Sciences 24(2023)17, 13133 (10.3390/ijms241713133)
  • Koi, L.; Bitto, V.; Weise, C. et al.
    Prognostic biomarkers for the response to the radiosensitizer nimorazole combined with RCTx: a pre-clinical trial in HNSCC xenografts
    Journal of Translational Medicine 21(2023), 576 (10.1186/s12967-023-04439-2)
  • Klusa, D.; Lohaus, F.; Franken, A. et al.
    Dynamics of CXCR4 positive circulating tumor cells in prostate cancer patients during radiotherapy
    International Journal of Cancer 152(2023), 2639-2654 (10.1002/ijc.34457)
  • Gantz, S.; Karsch, L.; Pawelke, J. et al.
    Direct visualization of proton beam irradiation effects in liquids by MRI
    Proceedings of the National Academy of Sciences of the United States of America 120(2023)23, e2301160120 (10.1073/pnas.2301160120)
  • Franke, F.; Michlikova, S.; Aland, S. et al.
    Efficient Radial-Shell Model for 3D Tumor Spheroid Dynamics with Radiotherapy
    Cancers 15(2023), 5645 (10.3390/cancers15235645)
  • Corti, C.; Cobanaj, M.; Dee, E. C. et al.
    Artificial intelligence in cancer research and precision medicine: Applications, limitations and priorities to drive transformation in the delivery of equitable and unbiased care
    Cancer Treatment Reviews 112(2023), 102498 (10.1016/j.ctrv.2022.102498)
  • Baumann, M.; Bacchus, C.; Aznar, M. C. et al.
    Are hybrid conferences the new standard?
    Radiotherapy and Oncology 128(2023), 109695 (10.1016/j.radonc.2023.109695)
  • Matesanz-Sánchez, R.; Peitzsch, M.; Seifert, M. et al.
    A novel role of exostosin glycosyltransferase 2 (EXT2) in glioblastoma cell metabolism, radiosensitivity and ferroptosis
    Cell Death and Differentiation 32(2025), 1664-1678 (10.1038/s41418-025-01503-w)
  • Gebauer, B.; Gantz, S.; Kunath, D. et al.
    Characterization of a commercial ionization chamber array with scanned proton beams for applications in MRI-guided proton therapy
    Medical Physics 52(2025)7, e17875 (10.1002/mp.17875)
  • Runge, R.; Reissig, F.; Herzog, N. et al.
    Combining Cisplatin with Different Radiation Qualities—Interpretation of Cytotoxic Effects In Vitro by Isobolographic Analysis
    Pharmaceuticals 16(2023)12, 1720 (10.3390/ph16121720)
  • Rahbar, K.; Wagner, S.; Schaeg, F. et al.
    First Experiences with the new 99mTc labelled PSMA ligand [99mTc]TcO-ABX474 in Patients with Advanced Prostate Cancer Prior to PSMA targeted Radioligand Therapy
    Journal of Nuclear Medicine 66(2024)suppl 2, 241711
  • Curvello, R.; Berndt, N.; Hauser, S. et al.
    Recreating metabolic interactions of the tumour microenvironment
    Trends in Endocrinology & Metabolism 35(2024), 518-532 (10.1016/j.tem.2023.12.005)
  • Berthold, J.; Bertschi, S.; Pietsch, J. et al.
    Clinical translation of Prompt-Gamma-Imaging for treatment verification in online-adaptive proton therapy: Overview of achievements and outlook
    International Journal of Particle Therapy 12(2024)Supplement, 100508 (10.1016/j.ijpt.2024.100508)
  • Towers, R.; Trombello, L.; Fusenig, M. et al.
    Bone marrow-derived mesenchymal stromal cells obstruct AML-targeting CD8+ clonal effector and CAR T cell function while promoting a senescence-associated phenotype
    Cancer Immunology, Immunotherapy 73(2024), 8 (10.1007/s00262-023-03594-1)
  • Miederer, M.; Benešová-Schäfer, M.; Mamat, C. et al.
    Alpha-emitting Radionuclides: Current Status and Future Perspectives
    Pharmaceuticals 17(2024), 76 (10.3390/ph17010076)
  • Janićijević, Ž.; Huang, T.; Sandoval Bojorquez, D. I. et al.
    Design and Development of Transient Sensing Devices for Healthcare Applications
    Advanced Science 11(2024)20, 2307232 (10.1002/advs.202307232)
  • Ludwig, F.-A.; Laurini, E.; Schmidt, J. et al.
    [¹⁸F]Fluspidine – a PET tracer for imaging of σ1 receptors in the central nervous system
    Pharmaceuticals 17(2024)166, 1-21 (10.3390/ph17020166)
  • Weiß, A.; Löck, S.; Xu, T. et al.
    Prediction of radiation pneumonitis using the effective α/β of lungs and heart in NSCLC patients treated with proton beam therapy
    Radiotherapy and Oncology 190(2024), 110013 (10.1016/j.radonc.2023.110013)
  • Samuels, M.; Falkenius, J.; Bar-Ad, V. et al.
    A Phase I Study of the DNA-PK Inhibitor Peposertib in Combination with Radiotherapy with or without Cisplatin in Patients with Advanced Head and Neck Tumors
    International Journal of Radiation Oncology Biology Physics 118(2024)3, 743-756 (10.1016/j.ijrobp.2023.09.024)
  • Mazzola, G. C.; Bergamaschi, L.; Vincini, M. et al.
    Patients’ needs in Proton Therapy: a survey among 10 European Facilities
    Clinical and Translational Radiation Oncology 43(2023), 100670 (10.1016/j.ctro.2023.100670)
  • Lococo, F.; Boldrini, L.; Diepriye, C.-D. et al.
    Lung cancer multi-omics digital human avatars for integrating precision medicine into clinical practice: the LANTERN study
    BMC Cancer 23(2023), 540 (10.1186/s12885-023-10997-x)
  • Elkhamisy, S. A.; Valentini, C.; Lattermann, A. et al.
    Normo-or hypo-fractionated photon or proton radiotherapy in the management of locally advanced unresectable pancreatic cancer: a systematic review
    Cancers 15(2023), 3771 (10.3390/cancers15153771)
  • Bookbinder, A.; Bobić, M.; Sharp, G. C. et al.
    An Operator-Independent Quality Assurance System for Automatically Generated Structure Sets
    Physics in Medicine and Biology 69(2024), 175003 (10.1088/1361-6560/ad6742)
  • Kreller, M.; Walther, M.; Brühlmann, S. A. et al.
    Production of medical radionuclides in the Center for Radiopharmaceutical Tumor Research – a status report
    Instruments 8(2024)1, 10 (10.3390/instruments8010010)
  • Zhao, X.; Kolbinger, F. R.; Distler, M. et al.
    Portable Droplet-Based Real-Time Monitoring of Pancreatic α-Amylase in Postoperative Patients
    Biosensors and Bioelectronics 251(2024), 116034 (10.1016/j.bios.2024.116034)
  • Szöllősi, D.; Hajdrik, P.; Tordai, H. et al.
    Molecular imaging of bacterial outer membrane vesicles based on bacterial surface display
    Scientific Reports 13(2023), 18752 (10.1038/s41598-023-45628-9)
  • Gorodetska, I.; Offerman, A.; Püschel, J. et al.
    ALDH1A1 drives prostate cancer metastases and radioresistance by interplay with AR- and RAR-dependent transcription
    Theranostics 14(2024)2, 714-737 (10.7150/thno.88057)
  • Drewitz, L.; Kegler, A.; Arndt, C. et al.
    Development Of A Novel ACE2 Decoy For Both SARS-CoV-2 Variant Neutralization And Infected Cell Elimination Via Unmodified Or CAR Modified Immune Cells
    Human Gene Therapy 34(2023), 92 (10.1089/hum.2023.29252.abstracts)
  • Brühlmann, S. A.; Walther, M.; Kopka, K. et al.
    Production of the PET radionuclide 61Cu via the 62Ni(p,2n)61Cu Nuclear Reaction
    EJNMMI Radiopharmacy and Chemistry 9(2024)1, 3 (10.1186/s41181-023-00233-z)
  • Gambetta, V.; Fredriksson, A.; Menkel, S. et al.
    The partial adaptation strategy for online-adaptive proton therapy: a proof of concept study in head and neck cancer patients
    Medical Physics 51(2024)8, 5572-5581 (10.1002/mp.17178)
  • Misko, V. R.; Baraban, L.; Makarov, D. et al.
    Selecting active matter according to motility in an acoustofluidic setup: Self-propelled particles and sperm cells
    Soft Matter 19(2023), 8635 (10.1039/D3SM01214J)
  • Horst, F. E.
    Calorimetry as a tool to improve the dosimetric accuracy in novel radiotherapy modalities
    Physics and Imaging in Radiation Oncology 28(2023), 100516 (10.1016/j.phro.2023.100516)
  • Horst, F. E.; Bodenstein, E.; Brand, M. et al.
    Dose and dose rate dependence of the tissue sparing effect at ultra-high dose rate studied for proton and electron beams using the zebrafish embryo model.
    Radiotherapy and Oncology 194(2024), 110197 (10.1016/j.radonc.2024.110197)
  • Janićijević, Ž.; Nguyen Le, T. A.; Baraban, L.
    Extended-gate field-effect transistor chemo- and biosensors: State of the art and perspectives
    Next Nanotechnology 3–4(2023), 100025 (10.1016/j.nxnano.2023.100025)
  • Wodtke, R.; Laube, M.; Hauser, S. et al.
    Preclinical evaluation of an ¹⁸F-labeled Nε-acryloyllysine piperazide for covalent targeting of transglutaminase 2
    EJNMMI Radiopharmacy and Chemistry 9(2024)1, 1 (10.1186/s41181‑023‑00231‑1)
  • Novgorodova, O.; Glatte, A.; Hentges, R. et al.
    Characterisation of a high granularity multi-channel prompt γ-ray detection system prototype for proton range verification based on the PETsys TOFPET2 ASIC
    Journal of Instrumentation 19(2024), P02030 (10.1088/1748-0221/19/02/P02030)
  • Craig, A.; Kogler, J.; Laube, M. et al.
    Preparation of 18F-Labeled Tracers Targeting Fibroblast Activation Protein via Sulfur [18F]Fluoride Exchange Reaction
    Pharmaceutics 15(2023)12, 2749 (10.3390/pharmaceutics15122749)
  • Patt, M.; Decristoforo, C.; de Martini, A. et al.
    The revision of the pharmaceutical legislation – it is time to act for nuclear medicine in Europe
    European Journal of Nuclear Medicine and Molecular Imaging 51(2023), 20-24 (10.1007/s00259-023-06472-1)
  • Broghammer, F.; Gouda, M.; Korovina, I. et al.
    Resistance of HNSCC cell models to pan-FGFR inhibition depends on the EMT phenotype associating with clinical outcome
    Molecular Cancer 23(2024), 39 (10.1186/s12943-024-01954-8)
  • González Soto, K. E.; Rodrigues Loureiro, L. R.; Bartsch, T. et al.
    Targeting colorectal cancer cells using AND-gated Adaptor RevCAR T-cells
    Frontiers in Immunology 14(2023), 1302354 (10.3389/fimmu.2023.1302354)
  • Krutzek, F.; Donat, C.; Stadlbauer, S.
    Chelator Impact: Investigating the Pharmacokinetic Behavior of Copper-64 Labeled PD-L1 Radioligands
    EJNMMI Radiopharmacy and Chemistry 9(2024), 14 (10.1186/s41181-024-00243-5)
  • Janićijević, Ž.; Nguyen Le, T. A.; Alsadig, A. et al.
    Methods gold standard in clinic millifluidics multiplexed extended gate field-effect transistor biosensor with gold nanoantennae as signal amplifiers
    Biosensors and Bioelectronics 241(2023), 115701 (10.1016/j.bios.2023.115701)
  • Rodrigues Loureiro, L. R.; Hoffmann, L.; Neuber, C. et al.
    Immunotheranostic target modules for imaging and navigation of UniCAR T-cells to strike FAP-expressing cells and the tumor microenvironment
    Journal of Experimental & Clinical Cancer Research 42(2023), 341 (10.1186/s13046-023-02912-w)
  • Zhao, X.; Ruelens, P.; Farr, A. D. et al.
    Population dynamics of cross-protection against β-lactam antibiotics in droplet microreactors
    Frontiers in Microbiology 14(2023), 1294790 (10.3389/fmicb.2023.1294790)
  • Zschaeck, S.; Klinger, B.; van den Hoff, J. et al.
    Combination of tumor asphericity and an extracellular matrix-related prognostic gene signature in non-small cell lung cancer patients
    Scientific Reports 13(2023), 20840 (10.1038/s41598-023-46405-4)
  • Korde, A.; Patt, M.; Selivanova, S. et al.
    Position Paper to facilitate patient access to radiopharmaceuticals - considerations for a suitable pharmaceutical regulatory framework
    EJNMMI Radiopharmacy and Chemistry 9(2024)1, 2 (10.1186/s41181-023-00230-2)
  • Klotz, D. M.; Schwarz, F.; Dubrovska, A. et al.
    Establishment and Molecular Characterization of an In Vitro Model for PARPi-Resistant Ovarian Cancer.
    Cancers 15(2023)15, 3774 (10.3390/cancers15153774)
  • Kubeil, M.; Suzuki, Y.; Casulli, M. A. et al.
    Exploring the Potential of Nanogels: From Drug Carriers to Radiopharmaceutical Agents
    Advanced Healthcare Materials 13(2023)1, 2301404 (10.1002/adhm.202301404)
  • Poldrack, R. A.; Markiewicz, C. J.; Appelhoff, S. et al.
    The Past, Present, and Future of the Brain Imaging Data Structure (BIDS)
    Imaging Neuroscience 2(2024), 1-19 (10.1162/imag_a_00103)
  • Korovina, I.; Elser, M.; Borodins, O. et al.
    β1 integrin mediates unresponsiveness to PI3Kα inhibition for radiochemosensitization of 3D HNSCC models
    Biomedicine and Pharmacotherapy 171(2024), 116217 (10.1016/j.biopha.2024.116217)
  • Kopp, I.; Cieslik, P.; Anger, K. et al.
    Bispidine Chelators for Radiopharmaceutical Applications with Lanthanide, Actinide and Main Group Metal Ions
    Inorganic Chemistry 62(2023)50, 20754-20768 (10.1021/acs.inorgchem.3c02340)
  • Pasternak, M.; Mirza, S.; Luciw, N. et al.
    Longitudinal cerebral perfusion in presymptomatic genetic frontotemporal dementia: GENFI results
    Alzheimer's & Dementia 20(2024)5, 3525-3542 (10.1002/alz.13750)
  • Krutzek, F.; Donat, C.; Stadlbauer, S.
    Exploring Hydrophilic PD-L1 Radiotracers Utilizing Phosphonic Acids: Insights Into Unforeseen Pharmacokinetics
    International Journal of Molecular Sciences 24(2023)20, 15088 (10.3390/ijms242015088)
  • Nenoff, L.; Amstutz, F.; Murr, M. et al.
    Review and recommendations on deformable image registration uncertainties for radiotherapy applications
    Physics in Medicine and Biology 68(2023), 24TR01 (10.1088/1361-6560/ad0d8a)
  • Wang, T.; Wang, J.; Chen, L. et al.
    Development of a Highly Specific 18F-labeled Radioligand for Imaging of Sigma-2 Receptor in Brain Tumor
    Journal of Medicinal Chemistry 66(2023)18, 12840-12857 (10.1021/acs.jmedchem.3c00735)
  • Cegla, P.; Hofheinz, F.; Burchardt, E. et al.
    Asphericity derived from [18F]FDG PET as a new prognostic parameter in cervical cancer patients
    Scientific Reports 13(2023)1, 8423 (10.1038/s41598-023-35191-8)
  • Maria Sag, S. J.; Menhart, K.; Hitzenbichler, F. et al.
    18F-FDG PET/CT-derived total lesion glycolysis predicts abscess formation in patients with surgically confirmed infective endocarditis: Results of a retrospective study at a tertiary center
    Journal of Nuclear Cardiology 30(2023), 2400-2414 (10.1007/s12350-023-03285-5)
  • Starke, S.; Zwanenburg, A.; Leger, K. et al.
    Multitask Learning with Convolutional Neural Networks and Vision Transformers Can Improve Outcome Prediction for Head and Neck Cancer Patients
    Cancers 15(2023)19, 4897 (10.3390/cancers15194897)
  • Elser, M.; Vehlow, A.; Juratli, T. et al.
    Simultaneous inhibition of discoidin domain receptor 1 and integrin αVβ3 radiosensitizes human glioblastoma cells
    American Journal of Cancer Research 13(2023)10, 4597-4612
  • Samimi, R.; Shiri, I.; Ahmadyar, Y. et al.
    Radiomics predictive modeling from dual-time-point FDG PET Ki parametric maps: application to chemotherapy response in lymphoma
    EJNMMI Research 13(2023)1, 70 (10.1186/s13550-023-01022-0)
  • Krutzek, F.; Donat, C.; Ullrich, M. et al.
    Design, Synthesis, and Biological Evaluation of Small Molecule Based Radioligands with Improved Pharmacokinetic Properties for Imaging of Programmed Death Ligand 1
    Journal of Medicinal Chemistry 66(2023)23, 15894-15915 (10.1021/acs.jmedchem.3c01355)
  • Azizova, A.; Prysiazhniuk, Y.; Wamelink, I. J. H. G. et al.
    Ten years of VASARI glioma features: Systematic review and meta-analysis of their impact and performance
    American Journal of Neuroradiology 45(2024)8, 1053-1062 (10.3174/ajnr.A8274)
  • Yaromina, A.; Koi, L.; Schuitmaker, L. et al.
    Overcoming radioresistance with the hypoxia-activated prodrug CP-506: A pre-clinical study of local tumour control probability
    Radiotherapy and Oncology 186(2023), 109738 (10.1016/j.radonc.2023.109738)
  • Lai, T. H.; Wenzel, B.; Dukic-Stefanovic, S. et al.
    Radiosynthesis and biological evaluation of [¹⁸F]AG-120 for PET imaging of the mutant isocitrate dehydrogenase 1 in gliomas
    European Journal of Nuclear Medicine and Molecular Imaging 51(2024), 1085-1096 (10.1007/s00259-023-06515-7)
  • Schellhammer, S.; Meric, I.; Löck, S. et al.
    Hybrid treatment verification based on prompt gamma-rays and fast neutrons: Multivariate modelling for proton range determination
    Frontiers in Physics 11(2023), 1295157 (10.3389/fphy.2023.1295157)
  • Xia, P.; Dubrovska, A.
    CD98 heavy chain as a prognostic biomarker and target for cancer treatment
    Frontiers in Oncology 13(2023), 1251100 (10.3389/fonc.2023.1251100)
  • Blei, M. K.; Drobot, B.; Kretzschmar, J. et al.
    Determination of Association Constants of Macropa-based Chelators for the Stable Complexation of Barium-131 and Lanthanum-133
    Nuclear Medicine and Biology 126-127(2023)S1, S245-S246 (10.1016/j.nucmedbio.2023.108722)
  • Blei, M. K.; Drobot, B.; Kretzschmar, J. et al.
    Bestimmung von logK-Werten macropa-basierter Chelatoren für die stabile Komplexierung von 131Ba, 223/224Ra und 133La
    Nuklearmedizin 62(2023), 149
  • Reissig, F.; Zarschler, K.; Novy, Z. et al.
    Entwicklung alternativer Verbindungen für die PSMA-Therapie mit Actinium-225
    Nuklearmedizin 62(2023), 147
  • Blei, M. K.; Waurick, L.; Reissig, F. et al.
    Equilibrium Thermodynamics of Macropa Complexes with Selected Metal Isotopes of Radiopharmaceutical Interest
    Inorganic Chemistry 62(2023)50, 20699-20709 (10.1021/acs.inorgchem.3c01983)
  • Löser, R.; Kuchar, M.; Wodtke, R. et al.
    Lysyl oxidases as targets for cancer therapy and diagnostic imaging
    ChemMedChem 18(2023)18, e202300331 (10.1002/cmdc.202300331)
  • Crespo, E.; Rodrigues Loureiro, L. R.; Arndt, C. et al.
    Turning an Immunosuppressive Marker Into a T-Cell Activating Signal: Using the RevCAR System to Target Immune Checkpoints
    Human Gene Therapy 54(2023) (10.1089/hum.2023.29252.abstracts)
  • Jósza, T.; Petr, J.; Payne, S. J. et al.
    MRI-based parameter inference for cerebral perfusion modelling in health and ischaemic stroke
    Computers in Biology and Medicine 166(2023), 107543 (10.1016/j.compbiomed.2023.107543)
  • Richter, S.; Steenblock, C.; Lemm, S. et al.
    Improving susceptibility of neuroendocrine tumors to radionuclide therapies: personalized approaches towards complementary treatments
    Theranostics 14(2024)1, 17-32 (10.7150/thno.87345)
  • Kegler, A.; Drewitz, L.; Arndt, C. et al.
    A novel ACE2 decoy for both neutralization of SARS-CoV-2 variants and killing of infected cells
    Frontiers in Immunology 14(2023), 1204543 (10.3389/fimmu.2023.1204543)
  • Gerlach, S.; Balling, F.; Schmidt, A. K. et al.
    Three-dimensional acoustic monitoring of laser-accelerated protons in the focus of a pulsed-power solenoid lens
    High Power Laser Science and Engineering 11(2023), e38 (10.1017/hpl.2023.16)
  • Braun, S.; Jelača, S.; Laube, M. et al.
    Synthesis and In Vitro Biological Evaluation of p-Carborane-based Di-tert-butylphenol Analogs
    Molecules 28(2023), 4547 (10.3390/molecules28114547)
  • Peschke, J.; Bergmann, R.; Mehnert, M. et al.
    FLT3-directed UniCAR T-cell therapy of Acute Myeloid Leukaemia
    British Journal of Haematology 202(2023)6, 1137-1150 (10.1111/bjh.18971)
  • Krutzek, F.; Donat, C.; Ullrich, M. et al.
    Design and Biological Evaluation of Small-Molecule PET-Tracers for Imaging of Programmed Death Ligand 1
    Cancers 15(2023), 2638 (10.3390/cancers15092638)
  • Ueberham, L.; Gündel, D.; Kellert, M. et al.
    Development of the Highly Affine Carborane-Based Cannabinoid Receptor Type 2 PET Ligand [18F]LUZ5-d8
    Journal of Medicinal Chemistry 66(2023), 5242-5260 (10.1021/acs.jmedchem.3c00195)
  • Wenzel, B.; Schmid, M.; Teodoro, R. et al.
    Radiofluorination of an anionic, azide-functionalized teroligomer by copper-catalyzed azide-alkyne cycloaddition
    Nanomaterials 13(2023)14, 2095 (10.3390/nano13142095)
  • Valentini, C.; Ebert, N.; Koi, L. et al.
    Preclinical trial comparing radiotherapy alone versus standard radiochemotherapy in three human papilloma virus (HPV) negative and three HPV-positive head and neck squamous cell carcinoma (HNSCC) xenograft tumour models.
    Radiotherapy and Oncology 183(2023), 109546 (10.1016/j.radonc.2023.109546)
  • Koevoets, E. W.; Petr, J.; Monninkhof, E. M. et al.
    Effect of physical exercise on brain perfusion in chemotherapy-treated breast cancer patients: a randomized controlled trial (PAM study)
    Journal of Magnetic Resonance Imaging 59(2024)5, 1667-1680 (10.1002/jmri.28967)
  • Wamelink, I. J. H. G.; Azizova, A.; Booth, T. C. et al.
    Brain tumor imaging without gadolinium-based contrast agents: Feasible or Fantasy?
    Radiology 310(2024)2 (10.1148/radiol.230793)
  • Striese, F.; Neuber, C.; Gräßel, S. et al.
    Preclinical Characterization of the 177Lu-Labeled Prostate Stem Cell Antigen (PSCA)-Specific Monoclonal Antibody 7F5
    International Journal of Molecular Sciences 24(2023)11, 9420 (10.3390/ijms24119420)
  • Pfeifer Serrahima, J.; Zhang, C.; Oberoi, P. et al.
    Multivalent adaptor proteins specifically target NK cells carrying a universal chimeric antigen receptor to ErbB2 (HER2)-expressing cancers
    Cancer Immunology, Immunotherapy 72(2023), 2905-2918 (10.1007/s00262-023-03374-x)
  • Braun, S.; Paskas, S.; Laube, M. et al.
    Carborane-based Tebufelone Analogs and their Biological Evaluation In Vitro
    ChemMedChem 18(2023), e202300206 (10.1002/cmdc.202300206)
  • Horst, F. E.; Beyreuther, E.; Bodenstein, E. et al.
    Passive SOBP generation from a static proton pencil beam using 3D-printed range modulators for FLASH experiments
    Frontiers in Physics 11(2023), 1213779. (10.3389/fphy.2023.1213779)
  • Grehn, M.; Mandija, S.; Miszczyk, M. et al.
    STereotactic Arrhythmia Radioablation (STAR): the Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary consortium (STOPSTORM.eu) and review of current patterns of STAR practice in Europe
    Europace 25(2023)4, 1284-1295 (10.1093/europace/euac238)
  • Michlikova, S.; Rabasco Meneghetti, A.; Löck, S. et al.
    Radiomics-based prediction of radiosensitivity from preclinical HNSCC histopathology images
    Radiotherapy and Oncology 182(2023)S1, S593 (10.1016/S0167-8140(23)08450-5)
  • Abdelfatah Saleh Hassan, H. A.; Mitwasi, N.; Ullrich, M. et al.
    Specific and safe targeting of glioblastoma using switchable and logic-gated RevCAR T cells
    Frontiers in Immunology 14(2023), 1166169 (10.3389/fimmu.2023.1166169)
  • Useini, L.; Komazec, T.; Laube, M. et al.
    Isonimesulide and its carborane analogues as isoform-selective COX inhibitors and antitumor agents
    Advanced Therapeutics 6(2023)8, 2300117 (10.1002/adtp.202300117)
  • Ullrich, M.; Brandt, F.; Löser, R. et al.
    Comparative saturation binding analysis of ⁶⁴Cu-labeled somatostatin analogs using cell homogenates and intact cells
    ACS Omega 8(2023)26, 24003-24009 (10.1021/acsomega.3c02755)
  • Suzuki, Y.; Clement, P.; Dai, W. et al.
    ASL lexicon and reporting recommendations: A consensus report from the ISMRM Open Science Initiative for Perfusion Imaging (OSIPI)
    Magnetic Resonance in Medicine 91(2024), 1743-1760 (10.1002/mrm.29815)
  • Corvino, A.; Reimold, M.; Beyreuther, E. et al.
    miniSCIDOM: a scintillator-based tomograph for volumetric dose reconstruction of single laser-driven proton bunches
    High Power Laser Science and Engineering 12(2024), e17 (10.1017/hpl.2024.1)
  • Reimold, M.; Assenbaum, S.; Beyreuther, E. et al.
    OCTOPOD: single bunch tomography for angular-spectral characterization of laser-driven protons
    High Power Laser Science and Engineering 11(2023), E68 (10.1017/hpl.2023.55)
  • Schieferecke, J.; Gantz, S.; Hoffmann, A. L. et al.
    Investigation of contrast mechanisms for MRI phase signal-based proton beam visualization in water phantoms
    Magnetic Resonance in Medicine 90(2023)5, 1776-1788 (10.1002/mrm.29752)
  • Köseer, A. S.; Di Gaetano, S.; Arndt, C. et al.
    Immunotargeting of Cancer Stem Cells.
    Cancers 15(2023), 1608 (10.3390/cancers15051608)
  • Nguyen Le, T. A.; Zhao, X.; Bachmann, M. et al.
    High-Throughput Gel Microbeads as Incubators for Bacterial Competition Study
    Micromachines 14(2023), 645 (10.3390/mi14030645)
  • Gebauer, B.; Baumann, K.-S.; Fuchs, H. et al.
    Proton dosimetry in a magnetic field: measurement and calculation of correction factors for a plane-parallel ionization chamber
    Medical Physics 51(2024)3, 2293-23005 (10.1002/mp.16797)
  • Borodins, O.; Broghammer, F.; Seifert, M. et al.
    Meta-analysis of expression and targeting of cell adhesion associated genes in nine cancer types – a one research lab re-evaluation
    Computational and Structural Biotechnology Journal 21(2023), 2824-2836 (10.1016/j.csbj.2023.04.017)
  • Spautz, S.; Haase, L.; Tschiche, M. et al.
    Comparison of 3D and 4D robustly optimized proton treatment plans for non-small cell lung cancer patients with tumour motion amplitudes larger than 5 mm
    Physics and Imaging in Radiation Oncology 27(2023), 100465 (10.1016/j.phro.2023.100465)
  • Bertschi, S.; Stützer, K.; Berthold, J. et al.
    Potential margin reduction in prostate cancer proton therapy when using prompt gamma imaging for online treatment verification
    Physics and Imaging in Radiation Oncology 26(2023), 100447 (10.1016/j.phro.2023.100447)
  • Fischer, A.; Kloos, S.; Maccio, U. et al.
    Metastatic pheochromocytoma and paraganglioma: somatostatin receptor 2 expression, genetics and therapeutic responses
    Journal of Clinical Endocrinology and Metabolism 108(2023), 2676-2685 (10.1210/clinem/dgad166)
  • Kiß, O.; Scott, P.; Behe, M. et al.
    Highlight selection of radiochemistry and radiopharmacy developments by editorial board
    EJNMMI Radiopharmacy and Chemistry 8(2023), 6 (10.1186/s41181-023-00192-5)
  • Sandoval Bojorquez, D. I.; Janićijević, Ž.; Palestina Romero, B. et al.
    Impedimetric Nanobiosensor for the Detection of SARS-CoV-2 Antigens and Antibodies
    ACS Sensors 8(2023)2, 576-586 (10.1021/acssensors.2c01686)
  • Köckerling, M.; Mamat, C.
    Synthesis, Dynamic NMR Characterization, and XRD Study of 2,4-Difluorobenzoyl-Substituted Piperazines
    Chemistry 7(2025), 162 (10.3390/chemistry7050162)
  • Wendler, M.; Kowe, S.
    Strahlenschutzmaßnahmen bei der Anwendung von PET-Nukliden in der Krebsforschung
    Strahlenschutz-Praxis 2(2023), 27-29
  • Witzmann, K.; Raschke, F.; Löck, S. et al.
    Unchanged perfusion in normal-appearing white and grey matter of glioma patients nine months after proton beam irradiation
    Acta Oncologica 62(2023)2, 141-149 (10.1080/0284186X.2023.2176254)
  • Padrela, B. E.; Lorenzini, L.; Collij, L. E. et al.
    Genetic, vascular, and amyloid determinants of cerebral blood flow in a preclinical population
    Journal of Cerebral Blood Flow and Metabolism 43(2023)10, 1726-1736 (10.1177/0271678X231178993)
  • Moyaert, P.; Padrela, B.; Morgan, C. et al.
    Imaging blood-brain barrier dysfunction: A state-of-the-art review from a clinical perspective
    Frontiers in Aging Neuroscience 15(2023), 1132077 (10.3389/fnagi.2023.1132077)
  • Hangel, G.; Schmitz-Abecassis, B.; Sollmann, N. et al.
    Advanced MR Techniques for preoperative Glioma Characterization - Part 2
    Journal of Magnetic Resonance Imaging 57(2023)6, 1676-1695 (10.1002/jmri.28663)
  • Hirschler, L.; Sollmann, N.; Schmitz-Abecassis, B. et al.
    Advanced MR Techniques for preoperative Glioma Characterization - Part 1
    Journal of Magnetic Resonance Imaging 57(2023)6, 1655-1675 (10.1002/jmri.28662)
  • Harrington, S.; Pyche, J.; Andrew, R. B. et al.
    Nemacol is a Small Molecule Inhibitor of C. elegans Vesicular Acetylcholine Transporter with Anthelmintic Potential
    Nature Communications 14(2023), 1816 (10.1038/s41467-023-37452-6)
  • Knieß, T.; Zessin, J.; Mäding, P. et al.
    Synthesis of [18F]FMISO, a hypoxia-specific imaging probe for PET, an overview from a radiochemist’s perspective
    EJNMMI Radiopharmacy and Chemistry 8(2023)1, 5 (10.1186/s41181-023-00190-7)
  • Brühlmann, S. A.; Walther, M.; Kreller, M. et al.
    Cyclotron-based Production of 67Cu for Radionuclide Theranostics Via the 70Zn(p,α)67Cu Reaction
    Pharmaceuticals 16(2023), 314 (10.3390/ph16020314)
  • Oancea, C.; Granja, C.; Marek, L. et al.
    Out-of-field measurements and simulations of a proton pencil beam in a wide range of dose rates using a Timepix3 detector: Dose rate, flux and LET
    Physica Medica, European Journal of Medical Physics 106(2023), 102529 (10.1016/j.ejmp.2023.102529)
  • Bachmann, L. M.; Hanl, M.; Feller, F. et al.
    Solid-Phase Parallel Synthesis of Dual Histone Deacetylase-Cyclooxygenase Inhibitors
    Molecules 28(2023), 1061 (10.3390/molecules28031061)
  • Kramer, C. S.; Kanagasundaram, T.; Matthias, J. et al.
    Efforts towards PET-activatable red-shifted silicon rhodamines and silicon pyronine dyes
    Pharmaceuticals 16(2023), 401 (10.3390/ph16030401)
  • Sihver, W.; Nitt-Weber, A.-K.; Behrens, S. et al.
    Functionality of a co-culture kidney model: testing the renal barrier with [18F]fluorodeoxyglucose
    Nuclear Medicine and Biology 126-127S(2023), S277
  • Sihver, W.; Liske, N.; Nitt-Weber, A.-K. et al.
    Radiopharmacological comparison of an Al18F- and 68Ga-labeled somatostatin agonist and antagonist in 2D and 3D models of BON-SSTR2 cells
    Nuclear Medicine and Biology 126-127S(2023), 108602
  • Sihver, W.; Nitt-Weber, A.-K.; Behrens, S. et al.
    Assessing the binding affinity of a 64Cu-labeled PSMA ligand in a micro physiological system
    Nuclear Medicine and Biology 127-127S(2023), S24-S25
  • Nikulin, P.; Zschaeck, S.; Maus, J. et al.
    A convolutional neural network with self-attention for fully automated metabolic tumor volume delineation of head and neck cancer in [18F]FDG PET/CT
    European Journal of Nuclear Medicine and Molecular Imaging 50(2023), 2751-2766 (10.1007/s00259-023-06197-1)
  • Meric, I.; Alagoz, E.; Hysing, L. et al.
    A hybrid multi-particle approach to range assessment-based treatment verification in particle therapy
    Scientific Reports 13(2023)1, 6709 (10.1038/s41598-023-33777-w)
  • Sepúlveda, C.; Gebauer, B.; Hoffmann, A. L. et al.
    Experimental dosimetric validation of an open-source treatment planning system for IMPT dose delivery at a horizontal PBS research beamline
    International Journal of Particle Therapy 10(2023)2, 334-334 (10.14338/IJPT-23-PTCOG61-10.2)
  • Trenkova, P.; Zhang, Y.; Toshito, T. et al.
    Real-time and online adaptive particle therapy in 10 years: a Delphi consensus analysis
    Radiotherapy and Oncology 182(2023)S1, S1623-S1624 (10.1016/S0167-8140(23)66795-7)
  • Berthold, J.; Pietsch, J.; Piplack, N. et al.
    Detectability of anatomical changes with prompt-gamma imaging: First systematic evaluation of clinical application during prostate-cancer proton therapy
    International Journal of Radiation Oncology Biology Physics 117(2023)3, 718-729 (10.1016/j.ijrobp.2023.05.002)
  • Heerwig, A.; Kick, A.; Sommerfeld, P. et al.
    The Impact of Nε-Acryloyllysine Piperazides on the Conformational Dynamics of Transglutaminase 2
    International Journal of Molecular Sciences 24(2023), 1650 (10.3390/ijms24021650)
  • Reimold, M.; Assenbaum, S.; Bernert, C. et al.
    Dosimetry for radiobiological in-vivo experiments at laser plasma-based proton accelerators
    Physics in Medicine and Biology 68(2023), 185009 (10.1088/1361-6560/acf025)
  • Schulze, S.; Neuber, C.; Möller, S. et al.
    Microdialysis reveals anti-inflammatory effects of sulfated glycosaminoglycanes in the early phase of bone healing
    International Journal of Molecular Sciences 24(2023), 2077 (10.3390/ijms24032077)
  • Schlesinger, M.; Jentschel, C.; Pietzsch, H.-J. et al.
    Copper-free click bioconjugation of technetium-99m complexes using strained cyclononyne derivatives
    Dalton Transactions 52(2023), 3024-3032 (10.1039/D2DT03965F)
  • Peng, X.; Janićijević, Ž.; Lemm, S. et al.
    Shell engineering in soft alginate-based capsules for culturing liver spheroids
    Biotechnology Journal 18(2023)6, 2200365 (10.1002/biot.202200365)
  • Afshar-Oromieh, A.; Eiber, M.; Fendler, W. et al.
    DGN-Handlungsempfehlung (S1-Leitlinie) PSMA-Liganden-PET/CT in der Diagnostik des Prostatakarzinoms Stand: 01/2022 AWMF-Registernummer: 031-055
    Nuklearmedizin 62(2023)1, 5-19 (10.1055/a-1984-8167)
  • Kanasuwan, A.; Deuther-Conrad, W.; Sarasamkan, J. et al.
    Selective a3b4 nicotinic acetylcholine receptor ligand as a potential tracer for drug addiction
    International Journal of Molecular Sciences 24(2023)4, 3614 (10.3390/ijms24043614)
  • Lindner, T.; Bolar, D. S.; Achten, E. et al.
    Current state and Guidance on Arterial Spin Labeling Perfusion MRI in Clinical Neuroimaging
    Magnetic Resonance in Medicine 89(2023)5, 2024-2047 (10.1002/mrm.29572)
  • Gebauer, B.; Pawelke, J.; Hoffmann, A. L. et al.
    Experimental dosimetric characterization of proton pencil beam distortion in a perpendicular magnetic field of an in-beam MR scanner
    Medical Physics 50(2023)11, 7294-7303 (10.1002/mp.16448)
  • Sadeghzadeh, M.; Wenzel, B.; Nikodemus, J. et al.
    Improved protocol for the radiosynthesis of [18F]FTC-146: A potent and selective sigma-1 receptor radioligand
    Journal of Labelled Compounds and Radiopharmaceuticals 66(2023)3, 116-125 (10.1002/jlcr.4018)
  • Starke, S.; Zwanenburg, A.; Leger, K. et al.
    Longitudinal and multimodal radiomics models for head-and-neck cancer outcome prediction
    Cancers 15(2023)3, 673 (10.3390/cancers15030673)
  • Xu, Y.; Rothe, R.; Voigt, D. et al.
    A self-assembled dynamic extracellular matrix-like hydrogel system with multi-scale structures for cell bioengineering applications
    Acta Biomaterialia 162(2023), 211-225 (10.1016/j.actbio.2023.03.015)
  • Horst, F. E.; Brand, M.; Hans, S. et al.
    Zebrafish Embryo Model of the FLASH Effect - In Regard to Böhlen et al.
    International Journal of Radiation Oncology Biology Physics 115(2023)4, 1006-1007 (10.1016/j.ijrobp.2022.11.015)
  • Brandt, F.; Ullrich, M.; Wodtke, J. et al.
    Enzymological characterization of ⁶⁴Cu-labeled neprilysin substrates and their application for modulating the renal clearance of targeted radiopharmaceuticals
    Journal of Medicinal Chemistry 66(2023)1, 516-537 (10.1021/acs.jmedchem.2c01472)
  • Behring, L.; Ruiz-Gomez, G.; Trapp, C. et al.
    Dipeptide-derived alkynes as potent and selective irreversible inhibitors of cysteine cathepsins
    Journal of Medicinal Chemistry 66(2023)6, 3818-3851 (10.1021/acs.jmedchem.2c01360)
  • Ullrich, M.; Richter, S.; Liers, J. et al.
    Epigenetic drugs in somatostatin type 2 receptor radionuclide theranostics and radiation transcriptomics in mouse pheochromocytoma models
    Theranostics 13(2023)1, 278-294 (10.7150/thno.77918)
  • Teodoro, R.; Gündel, D.; Deuther-Conrad, W. et al.
    Synthesis, Structure–Activity Relationships, Radiofluorination, and Biological Evaluation of [18F]RM365, a Novel Radioligand for Imaging the Human Cannabinoid Receptor Type 2 (CB2R) in the Brain with PET
    Journal of Medicinal Chemistry 66(2023)20, 13991–14010 (10.1021/acs.jmedchem.3c01035)
  • Krüger-Genge, A.; Köhler, S.; Laube, M. et al.
    Anti-cancer prodrug cyclophosphamide exerts thrombogenic effects on human venous endothelial cells independent of CYP450 activation – relevance to thrombosis
    Cells 12(2023), 1965 (10.3390/cells12151965)
  • Fan, H.; Mutsaerts, H. J. M. M.; Anazodo, U. et al.
    The Open Science Initiative for Perfusion Imaging (OSIPI): ASL Pipeline inventory
    Magnetic Resonance in Medicine 91(2024), 1787-1802 (10.1002/mrm.29869)
  • Dijsselhof, M.; Barboure, M.; Stritt, M. et al.
    The value of arterial spin labelling perfusion MRI in brain age prediction
    Human Brain Mapping 44(2023)7, 2754-2766 (10.1002/hbm.26242)
  • Schieferecke, J.; Gantz, S.; Karsch, L. et al.
    MRI magnitude signal-based proton beam visualisation in water phantoms reflects composite effects of beam-induced buoyant convection and radiation chemistry
    Physics in Medicine and Biology 68(2023), 185002 (10.1088/1361-6560/acf2e0)
  • Arndt, C.; Tunger, A.; Wehner, R. et al.
    Palbociclib impairs the proliferative capacity of activated T cells while retaining their cytotoxic efficacy
    Frontiers in Pharmacology 14(2023), 970457 (10.3389/fphar.2023.970457)
  • Paßler, F.; Belke, L.; Reissig, F. et al.
    Preparation of HOPO-containing lariate ethers based on the diaza-18-crown-6 scaffold
    Chemical Papers 78(2024), 4157-4164 (10.1007/s11696-024-03376-8)
  • Berthold, J.; Hueso González, F.; Wohlfahrt, P. et al.
    Prompt-gamma based treatment verification: Multi-institutional benchmark experiment of a prompt-gamma-imaging and a prompt-gamma-spectroscopy prototype system using an anthropomorphic head phantom
    International Journal of Particle Therapy 9(2023)4, 306-470 (10.14338/IJPT-23-PTCOG60-9.4)
  • Nickl, R.; Hauser, S.; Pietzsch, J. et al.
    Significance of pulmonary endothelial injury and the role of cyclooxygenase-2 and prostanoid signaling
    Bioengineering 10(2023)1, 117 (10.3390/bioengineering10010117)
  • Soltwedel, J.; Suckert, T.; Beyreuther, E. et al.
    Slice2Volume: Fusion of multimodal medical imaging and light microscopy data of irradiation-injured brain tissue in 3D
    Radiotherapy and Oncology 182(2023), 109591 (10.1016/j.radonc.2023.109591)