MHELTHERA Publications

2023

  • I. Kopp, P. A. Cieslik, K. Anger, T. Josephy, L. Neupert, G. Velmurugan, M. Gast, H. Wadepohl, S. A. Brühlmann, M. Walther, K. Kopka, M. Bachmann, H. Stephan, M. Kubeil, P. Comba

    Bispidine Chelators for Radiopharmaceutical Applications with Lanthanide, Actinide, and Main Group Metal Ions 

    Inorg. Chem. 2023, in press.    https://pubs.acs.org/doi/full/10.1021/acs.inorgchem.3c02340

  • M. Kubeil, Y. Suki, M. A. Casulli, R. Kamal, T. Hashimoto, M. Bachmann, T. Hayashita, H. Stephan

    Exploring the Potential of Nanogels: From Drug Carriers to Radiopharmaceutical Agents

    Adv. Healthcare Mater. 2023, 2301404    https://doi.org/10.1002/adhm.202301404

  • Ž. Janićijević, T. A. Nguyen-Le, A. Alsadig, I. Cela, R. Zilénaite, T. Hossain Tonmoy, M. Kubeil, M. Bachmann, L. Baraban

    Methods gold standard in clinic millifluidics multiplexed extended gate field-effect transistor biosensor with gold nanoantennae as signal amplifiers

    Biosens. Bioelectron. 2023, 241, 115701.    https://doi.org/10.1016/j.bios.2023.115701

  • X. Peng, Ž. Janićijević, S. Lemm, M. Laube, J. Pietzsch, M. Bachmann, L. Baraban

    Shell engineering in soft alginate-based capsules for culturing liver spheroids 

    Biotechnology Journal 2023, 2200365.     https://doi.org/10.1002/biot.202200365

  • T. A. Nguyen-Le, X. Zhao, M. Bachmann, P. Ruelens, J. A. G. M. d Visser, L. Baraban

    High-Throughput Gel Microbeads as Incubators for Bacterial Competition Study

    Micromachines 2023, 14, 645.    https://doi.org/10.3390/mi14030645

2022

  • P. Cieslik, M. Kubeil, K. Zarschler, M. Ullrich, F. Brandt, K. Anger, H. Wadepohl, K. Kopka, M. Bachmann, J. Pietzsch, H. Stephan, P. Comba

    Toward Personalized Medicine: One Chelator for Imaging and Therapy with Lutetium-177 and Actinium-225

    J. Am. Chem. Soc. 2022, 144, 21555.     https://doi.org/10.1021/jacs.2c08438

  • V. Sessi, B. Ibarlucea, F. Seichepine, S. Klinghammer, I. Ibrahim, A. Heinzig, N. Szabo, T. Mikolajick, A. Hierlemann, U. Frey, W. M. Weber, L. Baraban, G. Cuniberti

    Multisite Dopamine Sensing With Femtomolar Resolution Using a CMOS Enabled Aptasensor Chip

    Front. Neurosci. 2022, 16, 875656.     

  • N. Mitwasi, C. Arndt, L. R. Loureiro, A. Kegler, F. Fasslrinner, N. Berndt, R. Bergmann, V. Hořejší, C. Rössig, M. Bachmann, A. Feldmann

    Targeting CD10 on B-Cell Leukemia Using the Universal CAR T-Cell Platform (UniCAR)

    Int. J. Mol. Sci. 2022, 23, 4920.     https://doi.org/10.3390/ijms23094920

  • C. Arndt, R. Bergmann, F. Striese , K. Merkel, D. Máthé, L. R. Loureiro , N. Mitwasi, A. Kegler, F. Fasslrinner, K. E. González Soto, C. Neuber, N. Berndt, N. Kovács, D. Szöllősi, N. Hegedűs, G. Tóth, J.-P. Emmermann, K. B. Harikumar, T. Kovacs, M. Bachmann, A. Feldmann
    Development and Functional Characterization of a Versatile Radio-/Immuno-theranostic Tool for Prostate Cancer Management
    Cancers 2022, 14, 1996.          https://doi.org/10.3390/cancers14081996
  • A. S. Köseer, L. R. Loureiro, J. Jureczek, N. Mitwasi, K. E. González Soto, J. Aepler, T. Bartsch, A. Feldmann, L. A. Kunz-Schughart, A. Linge, M. Krause, M. Bachmann, C. Arndt, A. Dubrovska
    Validation of CD98hc as a Therapeutic Target for a Combination of Radiation and Immunotherapies in Head and Neck Squamous Cell Carcinoma
    Cancers 2022, 14, 1677.        https://doi.org/10.3390/cancers14071677
  • M. Kubeil, I. I. Santana Martinez, M. Bachmann, K. Kopka, K. L. Tuck, H. Stephan
    Dual-Labelling Strategies for Nuclear and Fluorescence Molecular Imaging: Current Status and Future Perspectives
    Pharmaceuticals 2022, 15, 432.     https://doi.org/10.3390/ph15040432
  • T. A. Nguyen-Le, T. Bartsch, R. Wodtke, F. Brandt, C. Arndt, A. Feldmann, D. I. Sandoval Bojorquez, A. Perez Roig, B. Ibarlucea, S. Lee, C.-K. Baek, G. Cuniberti, R. Bergmann, E. Puentes-Cala, J. Andrés Soto, B. T. Kurien, M. Bachmann, L. Baraban
    Nanosensors in clinical development of CAR-T cell immunotherapy
    Biosens. Bioelectron. 2022, 114124. .       https://doi.org/10.1016/j.bios.2022.114124

Previous Joint Publications

2011-2021

  • C. Arndt, L. R. Loureiro, A. Feldmann, J. Jureczek, R. Bergmann, D. Máthé, N. Hegedüs, N. Berndt, S. Koristka, N. Mitwasi, F. Fasslrinner, C. Lamprecht, A. Kegler, A. Hoffmann, T. Bartsch, A. S. Köseer, G. Egan, M. Schmitz, V. Hořejší, M. Krause, A. Dubrovska, M. Bachmann
    UniCAR T cell immunotherapy enables efficient elimination of radioresistant cancer cells
    Oncoimmunology 2020, 9, (doi: 10.1080/2162402X.2020.1743036).
  • D. C. Senevirathna, M. V. Werrett, M. Kubeil, H. Stephan, P. C. Andrews
    Synthesis, Structural Characterisation, and Cytotoxicity Studies of Bi, W, and Mo containing Homo- and Hetero-bimetallic Polyoxometalates
    Dalton Trans. 2019, 48, 15962-15969.
  • A. Nsubuga, K. Zarschler, M. Sgarzi, B. Graham, H. Stephan, T. Joshi
    Utilizing Photocrosslinking of Polydiacetylenes (PDAs) for the Preparation of “Stealth” Upconverting Nanoparticles (UCNPs)
    Angew. Chem. Int. Ed. 2018, 57, 16036-16040; Angew. Chem. 2018, 130, 16268-16272.
  • A. Nsubuga, M. Sgarzi, K. Zarschler, M. Kubeil, R. Hübner, R. Steudtner, B. Graham, T. Joshi, H. Stephan
    Facile Preparation of Multifunctionalisable ‘Stealth’ Upconverting Nanoparticles for Biomedical Applications
    Dalton Trans. 2018, 47, 8595-8604.
  • M. Kubeil, R. R. Vernooij, C. Kubeil, B. Wood, B. Graham, H. Stephan, L. Spiccia
    Studies of carbon monoxide release from ruthenium(II) bipyridine carbonyl complexes upon UV light exposure
    Inorg. Chem. 2017, 56, 5941-5952.
  • R. Bergmann, M. Kubeil, K. Zarschler, S. Chhabra, R. B. Tajhya, M. Bachmann, C. Beeton, M. W. Pennington, R. S. Norton, H. Stephan
    Distribution and dynamics of the Kv1.3-blocking peptide HsTX1[R14A] in experimental rats
    Sci. Reports 2017, 7, article 3756.
  • K. Pombo-Garcia, C. Rühl, T. Joshi, R. Lam, C.-S. Ang, P. J. Scammells, P. Comba, L. Spiccia, B. Graham, H. Stephan
    Zwitterionic Modifications of Ultrasmall Iron Oxide Nanoparticles for Reduced Corona Formation
    ChemPlusChem 2017, 82, 638-646.
  • K. Pombo-García, S. Weiss, K. Zarschler, C.-S. Ang, R. Hübner, J. Pufe, S. Meister, J. Seidel, J. Pietzsch, L. Spiccia, H. Stephan, B. Graham
    Zwitterionic polymer-coated ultrasmall superparamagnetic iron oxide nanoparticles with low protein interaction and high biocompatibility
    ChemNanoMat 2016, 2, 959-971.
  • K. Viehweger, L. Barbaro, K. Pombo García, T. Joshi, G. Geipel, J. Steinbach, H. Stephan, L. Spiccia, B. Graham
    EGF receptor-targeting peptide conjugate incorporating a near-IR fluorescent dye and a novel 1,4,7-triazacyclononane-based 64Cu(II) chelator assembled via click chemistry
    Bioconjugate Chem. 2014, 25, 1011-1022.
  • K. Pombo-García, K. Zarschler, L. Barbaro, J. A. Barreto, W. O’ Malley, L. Spiccia, H. Stephan, B. Graham
    Zwitterionic-coated „stealth“ nanoparticles for biomedical applications: recent advances in countering biomolecular corona formation and uptake by the monomolecular phagocyte system
    Small 2014, 10, 2516-2529.
  • R. Bergmann, A. Ruffani, B. Graham, L. Spiccia, J. Steinbach, J. Pietzsch, H. Stephan
    Synthesis and radiopharmacological evaluation of 64Cu-labeled bombesin analogs featuring a bis(2-pyridylmethyl)-1,4,7-triazacyclononane chelator
    Eur. J. Med. Chem. 2013, 70, 434-446.
  • K. Pombo-García, K. Zarschler, J. A. Barreto, J. Hesse, L. Spiccia, B. Graham, H. Stephan
    Design, synthesis, characterisation and in vitro studies of hydrophilic, colloidally-stable, 64Cu(II)-labelled, ultra-small iron oxide nanoparticles in a range of human cell lines
    RSC Adv. 2013, 3, 22443-22454.
  • J. A. Barreto, M. Matterna, B. Graham, H. Stephan, L. Spiccia
    Synthesis, Colloidal Stability and 64Cu Labelling of Iron Oxide Nanoparticles Bearing Different Macrocyclic Ligands
    New J. Chem. 2011, 35, 2705-2712.
  • J. A. Barreto, W. O’Malley, M. Kubeil, B. Graham, H. Stephan, L. Spiccia
    Nanomaterials: applications in cancer imaging and therapy
    Adv. Mater. 2011, 23, H18-H40.