Bioanorganische Chemie und Pathobiochemie (Chem-Ma-B01)
Lecturers |
Prof. Dr. Jens Pietzsch (Lecturer in charge) Dr. Manja Kubeil, Dr. Markus Laube, Dr. Sandra Hauser, Dr. Martin Ullrich |
Information on the courses |
The module Chem-Ma-B01 is offered in the teacher training programs GY and BS as module MN-SEGY-CHE-20F or MN-SEBS-CHE-20F. The lecture Pathobiochemistry/Medical Biochemistry II is offered as part of the module Chem-Ma-TB07 of the consecutive Master's program in Biochemistry. The next lectures will be offered in English from the winter semester 2025/2026. If you are interested in internship semesters/master theses, please have a look at here. |
Location/Time |
Seminar room CHE/153 The lecture takes place weekly on Wednesdays in the 4th double lesson (1.00 pm to 2.30 pm; s.t. - Bioinorganic Chemistry) and in the 5th double lesson (2.50 pm to 4.20 pm; s.t. - Pathobiochemistry/Medical Biochemistry II). Bioinorganic Chemistry: lecture finished Pathobiochemistry/Medicinal Biochemistry II: lecture finished Seminar: finished Please also refer to the corresponding entries in OPAL and SELMA. |
Online | In the case of an online lecture, the dial-in modalities (link (Zoom/BBB)) will be announced here accordingly. |
Content |
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Exams |
Modules Chem-Ma-B01 / MN-SEGY-CHE-20F / MN-SEBS-CHE-20F Oral examination (individual examination, 60 min): Dates will be arranged individually 11.02. and 12.02. at HZDR, Building 805, Room 265 (11.02.) or Room 151 (seminar room, 12.02.) The oral examination can be taken in German or English. Module Chem-Ma-TB07 Written exam: Date will be announced in time The exam language is English. |
Links |
To prepare for the lecture Bioinorganic Chemistry, please use the lecture notes (scripts see below). *** To prepare for the lecture Pathobiochemistry/Medical Biochemistry II, please use the lecture notes and the reading material for self-study (Skript). For both lectures, please also recapitulate the contents of previous chemistry and biochemistry lectures, especially on
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Course of the academic year
Pathobiochemistry schedule
- Introduction to pathobiochemistry
- General and special pathobiochemistry
- Signal transduction
- Inflammation
- Inflammatory diseases
- Atherogenesis
- Diseases of the lipoprotein metabolism
- Metabolic syndrome
- Inflammogenesis of tumors
Bioinorganic Chemistry schedule
Thema | |
L1 - Overview Bioinorganic chemistry, trace elements, bioligands |
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L2 - Basic Principles of Coordination Chemistry |
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L3 - Alkaline metals (sodium, potassium) Recognition of spherical species, membrane pumps and channels |
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L4 - Alkaline earth metals (calcium, magnesium) Biomineralization, messenger substances and structure formers |
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L5 - Zinc, Copper enzymatic catalysis, regulatory functions |
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L6 - Manganese, Cobalt, Nickel Photosynthesis, Cobalamines, Nickel - a long overlooked biometal |
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L7 - Iron Oxygen transport, Heme-Fe and None-heme-Fe |
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L8 - Molybdenum, Vanadium, Chromium, Tungsten Nitrogen fixation, Haloperoxidases, Cr(III) - role in humans? |
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L9 - Gasotransmitters NO, CO, H2S Biosynthesis, reactive oxygen and nitrogen species |
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L10 - Toxic metals Pb, Hg, Cd, As, Chelate therapy |
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L11 - Inorganic drugs Diagnostics and therapeutics |
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L12 - Radioactive metals in the environment and medicine natural and artificial radioisotopes |
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L13 - Seminar |