Department of Biophysics


Research

The Biophysics Department conducts interdisciplinary research at the interface of biomolecular function, physical chemistry and radiochemistry. The activities contribute to the Helmholtz Research Programmes Nuclear Safety and Cancer Research in the Helmholtz-Association. We are member of the Cluster of Excellence "Physics of Life" (PoL) in Dresden. 

We are particularly interested in:

  • structural and dynamic aspects of biomembranes
  • conformational transitions in membrane proteins
  • interactions between (radio)metals and biomolecules
  • effects of metals and radionuclides on the metabolism of microorganisms (Televised MDR report)

Education

The Biophysics department participates in the Dresden International Graduate School for Biomedicine and Bioengineering (DIGS-BB) supported by the Excellence Initiative of the German federal and state governments.

Practicals on Molecular Spectroscopy and Calorimetry are offered. The following lectures are held at the technische Universität Dresden and are elgible for the Master Specialization "Soft Condensed Matter and Biological Physics":

  • Biological Thermodynamics (English, summer semester)
  • Biophysical Methods (German, winter semester)

Seminar lectures  for the International BIOTEC-Master Programme,

  • Vibrational Spectroscopy (English)
  • Absorption and Fluorescence Spectroscopy (English)

Experimental Methods

  • Fourier transform infrared spectroscopy
  • Circular dichroism
  • Static and time-resolved fluorescence spectroscopy
  • Calorimetry
  • Mass-Spectroscopy

Spectroscopic data are evaluated in combination with Density Functional Theory to understand photochemoical and photophysical properties of organic complexes of actinides.


Latest publication

Selective recovery of Cu from copper mold production waste by organic ligands

Choudhary, S.; Dhiman, S.; Hintersatz, C.; Matys, S.; Kutschke, S.; Tsushima, S.; Pollmann, K.; Saravanan, V.; Jain, R.

Abstract

In the present study, organic acids - oxalic acid, citric acid, tartaric acid and siderophore Desferrioxamine B were evaluated for their efficiencies to selectively recover Cu from its mold production waste. XRD analysis showed that copper mold production waste mainly consisted of Fe and Cu. The complete dissolution of this waste in aqua regia and subsequent analysis via ICP-MS revealed metal contents of 355.3 mg/g Fe and 293.9 mg/g Cu. Among all the organic acids, citric acid had the highest leaching efficiency (58.5 %) for Fe while leaching <1 % of Cu. Whereas, the leaching of Cu and Fe was poor in oxalic acid medium and Cu leaching was also negligible in tartaric acid medium. Only Fe showed 11.2 % leaching efficiency at 2 mol/L tartaric acid. The step-by-step leaching of production waste with citric acid lead to 100 % leaching of Fe while leaving 93.1 % of Cu with a yield of >99 % in the solid residue in the 4th step. Further, the siderophore Desferrioxamine B could effectively leach Fe (91.2 %) while 21.4 % leaching of Cu in 30 days. The presence of Fe impedes the leaching of Cu from the waste as demonstrated by leaching and DFT calculations due to higher stability of Fe-citrate and Fe-desferrioxamine B complex compared to Cu-organic complexes. This recycling technique described herein is simple, reliable and environmentally friendly for recovery of Cu from copper mold production waste.

Keywords: Selective leaching; Citric acid; Recovery; Desferrioxamine B; Thermodynamic parameters; Density functional theory calculations

Related publications

Permalink: https://www.hzdr.de/publications/Publ-39271


More publications


Team


Head

NameBld./Office+49 351 260Email
Prof. Dr. Karim Fahmy801/P3012952
3601
k.fahmyAthzdr.de

Employees

NameBld./Office+49 351 260Email
Jenny Philipp801/P3033247
3568
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Prof. Dr. Satoru Tsushima801/P3022978
s.tsushimaAthzdr.de

Other employees

NameBld./Office+49 351 260Email
Dr. Charlotte Kielar801/P3033247
3892
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Physical Chemistry of Biomolecular Condensates

Head

NameBld./Office+49 351 260Email
Dr. Ellen Adams801/P3012911
e.adamsAthzdr.de

Employees

NameBld./Office+49 351 260Email
Artur Czajkowski801/P3033375
a.czajkowskiAthzdr.de
Likhitha Chakra Priya Pulibandla801/P3033375
l.pulibandlaAthzdr.de
Manthan Raj801/P3033375
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Juliane Tippmannj.tippmannAthzdr.de
Abhirami Udayabanua.udayabanuAthzdr.de