Myocardial uptake and biodistribution of newly designed technetium-labelled fatty acid analogues


Myocardial uptake and biodistribution of newly designed technetium-labelled fatty acid analogues

Heintz, A. C.; Jung, C. M.; Stehr, S. N.; Mirtschink, P.; Walther, M.; Pietzsch, J.; Bergmann, R.; Pietzsch, H.-J.; Spies, H.; Wunderlich, G.; Kropp, J.; Deussen, A.

In an effort to develop 99mTc-labelled fatty acids (FAs) for myocardial metabolism and flow imaging, several 99mTc analogues according to the ‘3+1’ and the ‘4+1’-mixed ligand approach were synthesized and myocardial extraction was evaluated in non-working isolated guinea pig hearts. Biodistribution patterns in guinea pigs were determined exemplarily of one FA analogue.

  • Nuclear Medicine Communications 28(2007)8, 637-647
    ISSN: 0143-3636

Permalink: https://www.hzdr.de/publications/Publ-10335
Publ.-Id: 10335