Cathepsin S inhibitors: WO2010070615
Cathepsin S inhibitors: WO2010070615
Löser, R.
This article evaluates a patent application of the company Medivir (SE/UK) describing the synthesis of dipeptide-derived alpha alpha-ketoamides containing a propylene glycine moiety in P1 as selective inhibitors of cathepsin S for the potential treatment of various systemic human diseases such as several autoimmune diseases, MS, rheumatoid arthritis, endometriasis and chronic pain. The claims of the patent are discussed in light of recent results in the field of cathepsin S research.
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Expert Opinion on Therapeutic Patents 21(2011)4, 585-591
DOI: 10.1517/13543776.2011.550574
ISSN: 1354-3776
Cited 3 times in Scopus
Permalink: https://www.hzdr.de/publications/Publ-15584
Publ.-Id: 15584