Convenient recycling and reuse of bombarded [18O]H2O for the production and the application of [18F]F


Convenient recycling and reuse of bombarded [18O]H2O for the production and the application of [18F]F

Rötering, S.; Franke, K.; Zessin, J.; Brust, P.; Füchtner, F.; Fischer, S.; Steinbach, J.

The limited availability and the increasing demands of [18O]H2O force the reuse of bombarded [18O]H2O for the production of [18F]F at least for the purposes of research. Therefore inorganic and organic contaminants have to be removed from the [18O]water. We present a simple and effective method of [18O]water purification including oxidation and distillation. The obtained recycled [18O]water has comparable properties to unused [18O]water. This was confirmed by a detailed comparison of produced radionuclides and their activities and the application of [18F]F in standardised radiotracer synthesis.

Keywords: purification of used [18O]water; recycling and reuse; production of [18F]fluoride; radiosynthesis; analysis methods

Permalink: https://www.hzdr.de/publications/Publ-20780
Publ.-Id: 20780