Convenient recycling and reuse of bombarded [18O]H2O for the production and the application of [18F]F‒
Convenient recycling and reuse of bombarded [18O]H2O for the production and the application of [18F]F‒
Rötering, S.; Franke, K.; Zessin, J.; Brust, P.; Füchtner, F.; Fischer, S.; Steinbach, J.
The limited availability and the increasing demands of [18O]H2O force the reuse of bombarded [18O]H2O for the production of [18F]F‒ at least for the purposes of research. Therefore inorganic and organic contaminants have to be removed from the [18O]water. We present a simple and effective method of [18O]water purification including oxidation and distillation. The obtained recycled [18O]water has comparable properties to unused [18O]water. This was confirmed by a detailed comparison of produced radionuclides and their activities and the application of [18F]F‒ in standardised radiotracer synthesis.
Keywords: purification of used [18O]water; recycling and reuse; production of [18F]fluoride; radiosynthesis; analysis methods
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Applied Radiation and Isotopes 101(2015), 44-52
Online First (2015) DOI: 10.1016/j.apradiso.2015.03.009
Cited 10 times in Scopus
Permalink: https://www.hzdr.de/publications/Publ-20780
Publ.-Id: 20780