Addressing multi-centre image registration of 3T arterial spin labeling images from the GENetic Frontotemporal dementia Initiative (GENFI)


Addressing multi-centre image registration of 3T arterial spin labeling images from the GENetic Frontotemporal dementia Initiative (GENFI)

Mutsaerts, H.; Thomas, D.; Petr, J.; de Vita, E.; Cash, D.; van Osch, M.; Groot, P.; van Swieten, J.; Laforce Jr, R.; Tagliavini, F.; Borroni, B.; Galimberti, D.; Rowe, J.; Graff, C.; Frisoni, G.; Finger, E.; Sorbi, S.; Mendonça, A.; Rossor, M.; Rohrer, J.; Masellis, M.; Macintosh, B.

One obstacle in multi-centre arterial spin labeling (ASL) studies is the variability attributed to differences between vendor- or site-specific ASL implementations. This multi-centre study compares spatial registration methods from ASL to 3D-T1, to reduce the between-subject variability of cerebral blood flow (CBF) maps. Our results demonstrate that choices of image registration have profound effects on ASL data collected using different pulse sequences and/or sites. A rigid-body registration of CBF images to segmented gray matter images produced the most robust similarity outcome as a standard approach across the different ASL implementations.

  • Contribution to proceedings
    24th Scientific Meeting and Exhibition of International Society for Magnetic Resonance in Medicine, 07.05.2016, Singapore, Singapore
    Proceedings of the 24th Scientific Meeting and Exhibition of International Society for Magnetic Resonance in Medicine
  • Poster
    24th Scientific Meeting and Exhibition of International Society for Magnetic Resonance in Medicine, 07.05.2016, Singapore, Singapore

Permalink: https://www.hzdr.de/publications/Publ-23696
Publ.-Id: 23696