Data-driven model for evaluation of cerebrovascular-reserve measurement with hypercapnia BOLD


Data-driven model for evaluation of cerebrovascular-reserve measurement with hypercapnia BOLD

Vondráčková, L.; Krukowski, P.; Gerber, J.; Linn, J.; Kybic, J.; Petr, J.

Hypercapnia BOLD with the breath-holding task is a technically easier and more clinically available alternative to cerebrovascular reserve (CVR) mapping than administration of CO enriched air using an air-tight mask. The disadvantage is complicated data evaluation in case the subject does not adhere to the breathing protocol completely. Here, a data-driven approach for evaluation is presented that is more robust to protocol deviations and produces a reasonable CVR map in most cases where the standard model-driven approach fails. This is demonstrated on randomized evaluation of CVR maps of a group of 86 subjects with stenosis or vessel occlusion.

  • Contribution to proceedings
    24th Scientific Meeting and Exhibition of International Society for Magnetic Resonance in Medicine, 07.05.2016, Singapore, Singapore
    Proceedings of the 24th Scientific Meeting and Exhibition of International Society for Magnetic Resonance in Medicine
  • Poster
    24th Scientific Meeting and Exhibition of International Society for Magnetic Resonance in Medicine, 07.05.2016, Singapore, Singapore

Permalink: https://www.hzdr.de/publications/Publ-23698
Publ.-Id: 23698