The LSO/APD array as a possible detector for in-beam PET in hadron therapy.


The LSO/APD array as a possible detector for in-beam PET in hadron therapy.

Kapusta, M.; Crespo, P.; Wolski, D.; Heidel, K.; Heinrich, L.; Hutsch, J.; Pawelke, J.; Sobiella, M.; Trzcinska, A.; Moszynski, M.; Enghardt, W.

We have studied the performance of finger like LSO:Ce (LSO) crystals coupled one by one to pixels of avalanche photodiode detector (APD) arrays during their operation in coincidence at 12C ion beams of parameters being typical for tumor irradiations. In a first step of these experiments the parameters of the detectors and the signal processing setup has been characterized off-beam, i.e. by means of beta+ radioactive sources (22Na, 68Ge). Afterwards, the apparatus was installed at the medical beam line of the heavy ion synchrotron (SIS) of the Gesellschaft für Schwerionenforschung (GSI) at Darmstadt, Germany. Here, the beta+ activity produced by nuclear fragmentation reactions of 12C 200.3 AMeV heavy ion beams with polymerized methyl methacrylate (PMMA) phantoms were measured. Furthermore, a 68Ge source was included into the in-beam experiment, in order to check the stability of the setup and to compare energy and time resolution before, during and after phantom irradiations. Additionally, it could be demonstrated by means of high resolution gamma-ray spectroscopy that LSO is not activated by the light projectile fragments escaping the patients downbeam during therapeutic irradiations. The experimental results indicate, that LSO scintillator is a suitable material for in-beam PET and, furthermore, the LSO/APD array is a feasible detector concept for in-beam monitoring of the dose application by means of PET.

  • Lecture (Conference)
    IEEE Nuclear Science Symposium and Medical Imaging Conference, Portland, USA, Oct. 19-25, 2003
  • IEEE Transactions on Nuclear Science 51(2004)4, 1389-1394
    DOI: 10.1109/TNS.2004.832318
    Cited 9 times in Scopus
  • Contribution to proceedings
    IEEE Nuclear Science Symposium and Medical Imaging Conference, Portland, USA, Oct. 19-25, 2003

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Publ.-Id: 5857