Fast user guided segmentation and quantification of volumes in 3-d datasets


Fast user guided segmentation and quantification of volumes in 3-d datasets

Pötzsch, C.; Hofheinz, F.; van den Hoff, J.

Positron emissions tomography studies typically contain serveral hundred tomographic images, which have to be analyzed to derive informations such as the volume of target structures (e.g. tumors). Available programs do not offer the necessary functionality because evaluation is limited to processing of individual tomographic images.

We present a newly developed tool for easy and fast evaluation of regions of interest in a volume orientated way. Examples of typical applications to microPET studies are presented.

To achive the aim the following key functionality was defined and implemented: For acceptance the tool should offer an easy and fast way of navigation through the three dimensional volumes. For that purpose three views are available, an orthogonal view, a multiple plane view and a maximum intensity projection view.

Interesting regions are enclosed by user defined masks to exclude regions of high activity background. A threshold guided automatic delineaction of interesting structures as well as an automatic segmentions of the thresholded data is used to find the target structures. These detected volumes of interest are delineated in realtime in all available views (including, especially, the maximum projection view) with a separate colormap for visual control through the operator. For each detected region the volume and parameters characterizing the tracer accumulation (maximum, minimum, mean, standard deviation, etc.) are provide. For post processing and archiving an export (XML and ASCII) as well as printing of these statistical values is possible.

  • Poster
    Annual Conference of the Academy of Molecular Imaging, 18.-23.03.2005, Orlando, Florida, USA
  • Abstract in refereed journal
    Molecular Imaging and Biology 7(2005)2, 152

Permalink: https://www.hzdr.de/publications/Publ-7388
Publ.-Id: 7388