The Feasibility of In-Beam PET for Therapeutic Beams of He-3


The Feasibility of In-Beam PET for Therapeutic Beams of He-3

Fiedler, F.; Crespo, P.; Parodi, K.; Sellesk, M.; Enghardt, W.

At present in-beam PET is the only possibility for an in-situ monitoring of the particle delivery in hadron tumour therapy. It has been implemented for clinical application at the carbon ion therapy facility of the Gesellschaft für Schwerionenforschung (GSI) Darmstadt. Several heavy ion treatment facilities are in planning or even construction stage. They will provide a variety of ions from protons to oxygen. The application of in-beam PET requires a precise knowledge of the spatial distribution of beam induced positron emitters in the irradiated volume. For the 3He-case experiments at GSI with three monoenergetic 3He-beams of 130.03 AMeV to 207.92 AMeV and mean intensities varying from 2.0 • 108 to 3.5 • 108 ions / s have been carried out. The beams were stopped in homogeneous thick targets consisting of PMMA, graphite and water, which were placed in the centre of the field of view of the PET-scanner at the experimental carbon ion therapy at GSI. Results on the production rate and the spatial distribution of 3He-ion induced +-activity are presented and compared with data from 12C-irradiation. The accuracy and resolution for determining the range of the 3He primary beams is deduced. Furthermore, energy dependent thick target cross sections for different reaction channels leading to positron emitters have been estimated from the experimental data.

Keywords: In-beam PET; 3He; Hadron Therapy

  • Poster
    Heavy Charged Particles in Biology and Medicine - ENLIGHT meeting, 15.-19.06.2005, Oropa, Italien
  • Contribution to proceedings
    Heavy Charged Particles in Biology and Medicine - ENLIGHT meeting, 15.-19.09.2005, Oropa, Italy
    Proceedings, 192-196

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Publ.-Id: 7824