Publications of Institute of Radiopharmaceutical Cancer Research

407 Publications

2024

Impact of Viscosity on Human Hepatoma Spheroids in Soft Core-Shell Microcapsules

Peng, X.; Janićijević, Ž.; Lemm, S.; Hauser, S.; Knobel, M.; Pietzsch, J.; Bachmann, M.; Baraban, L.

Production of medical radionuclides in the Center for Radiopharmaceutical Tumor Research – a status report

Kreller, M.; Walther, M.; Brühlmann, S. A.; Knieß, T.; Kopka, K.

Involved research facilities

  • PET-Center
  • ZRT

Preclinical evaluation of an ¹⁸F-labeled Nε-acryloyllysine piperazide for covalent targeting of transglutaminase 2

Wodtke, R.; Laube, M.; Hauser, S.; Meister, S.; Ludwig, F.-A.; Fischer, S.; Kopka, K.; Pietzsch, J.; Löser, R.

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  • PET-Center

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Improving susceptibility of neuroendocrine tumors to radionuclide therapies: personalized approaches towards complementary treatments

Richter, S.; Steenblock, C.; Lemm, S.; Ziegler, C. G.; Bechmann, N.; Nölting, S.; Pietzsch, J.; Ullrich, M.

Shell engineering in soft alginate-based capsules for culturing liver spheroids

Peng, X.; Janićijević, Ž.; Lemm, S.; Laube, M.; Pietzsch, J.; Bachmann, M.; Baraban, L.

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2023

Molecular imaging of bacterial outer membrane vesicles based on bacterial surface display

Szöllősi, D.; Hajdrik, P.; Tordai, H.; Horváth, I.; Veres, D. S.; Gillich, B.; Das Shailaja, K.; Smeller, L.; Bergmann, R.; Bachmann, M.; Mihály, J.; Gaál, A.; Jezsó, B.; Barátki, B.; Kövesdi, D.; Bősze, S.; Szabó, I.; Felföldi, T.; Oszwald, E.; Padmanabhan, P.; Zoltán Gulyás, B.; Hamdani, N.; Máthé, D.; Varga, Z.; Szigeti, K.

Radiosynthesis and biological evaluation of [¹⁸F]AG-120 for PET imaging of the mutant isocitrate dehydrogenase 1 in gliomas

Lai, T. H.; Wenzel, B.; Dukic-Stefanovic, S.; Teodoro, R.; Arnaud, L.; Maisonial-Besset, A.; Weber, V.; Moldovan, R.-P.; Meister, S.; Pietzsch, J.; Kopka, K.; Juratli, T. A.; Deuther-Conrad, W.; Toussaint, M.

Lysyl oxidases as targets for cancer therapy and diagnostic imaging

Löser, R.; Kuchar, M.; Wodtke, R.; Neuber, C.; Belter, B.; Kopka, K.; Santhanam, L.; Pietzsch, J.

A novel ACE2 decoy for both neutralization of SARS-CoV-2 variants and killing of infected cells

Kegler, A.; Drewitz, L.; Arndt, C.; Daglar, C.; Rodrigues Loureiro, L. R.; Mitwasi, N.; Neuber, C.; González Soto, K. E.; Bartsch, T.; Baraban, L.; Ziehr, H.; Heine, M.; Nieter, A.; Moreira-Soto, A.; Kühne, A.; Drexler, J. F.; Seliger, B.; Laube, M.; Máthé, D.; Pályi, B.; Hajdrik, P.; Forgách, L.; Kis, Z.; Szigeti, K.; Bergmann, R.; Feldmann, A.; Bachmann, M.

Involved research facilities

  • ZRT

Synthesis and In Vitro Biological Evaluation of p-Carborane-based Di-tert-butylphenol Analogs

Braun, S.; Jelača, S.; Laube, M.; George, S.; Hofmann, B.; Lönnecke, P.; Steinhilber, D.; Pietzsch, J.; Mijatović, S.; Maksimović-Ivanić, D.; Hey-Hawkins, E.

FLT3-directed UniCAR T-cell therapy of Acute Myeloid Leukaemia

Peschke, J.; Bergmann, R.; Mehnert, M.; González Soto, K. E.; Rodrigues Loureiro, L. R.; Mitwasi, N.; Kegler, A.; Altmann, H.; Wobus, M.; Máthé, D.; Szigeti, K.; Feldmann, A.; Bornhäuser, M.; Bachmann, M.; Fasslrinner, F.; Arndt, C.

Preclinical Characterization of the 177Lu-Labeled Prostate Stem Cell Antigen (PSCA)-Specific Monoclonal Antibody 7F5

Striese, F.; Neuber, C.; Gräßel, S.; Arndt, C.; Ullrich, M.; Steinbach, J.; Pietzsch, J.; Bergmann, R.; Pietzsch, H.-J.; Sihver, W.; Frenz, M.; Feldmann, A.; Bachmann, M.

Involved research facilities

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Carborane-based Tebufelone Analogs and their Biological Evaluation In Vitro

Braun, S.; Paskas, S.; Laube, M.; George, S.; Hofmann, B.; Lönnecke, P.; Steinhilber, D.; Pietzsch, J.; Mijatović, S.; Maksimović-Ivanić, D.; Hey-Hawkins, E.

Specific and safe targeting of glioblastoma using switchable and logic-gated RevCAR T cells

Abdelfatah Saleh Hassan, H. A.; Mitwasi, N.; Ullrich, M.; Kubeil, M.; Toussaint, M.; Deuther-Conrad, W.; Neuber, C.; Arndt, C.; Rodrigues Loureiro, L. R.; Kegler, A.; González Soto, K. E.; Belter, B.; Rössig, C.; Pietzsch, J.; Frenz, M.; Bachmann, M.; Feldmann, A.

Involved research facilities

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Isonimesulide and its carborane analogues as isoform-selective COX inhibitors and antitumor agents

Useini, L.; Komazec, T.; Laube, M.; Lönnecke, P.; Schädlich, J.; Mijatović, S.; Maksimović-Ivanić, D.; Pietzsch, J.; Hey-Hawkins, E.

Comparative saturation binding analysis of ⁶⁴Cu-labeled somatostatin analogs using cell homogenates and intact cells

Ullrich, M.; Brandt, F.; Löser, R.; Pietzsch, J.; Wodtke, R.

Involved research facilities

  • ZRT

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Metastatic pheochromocytoma and paraganglioma: somatostatin receptor 2 expression, genetics and therapeutic responses

Fischer, A.; Kloos, S.; Maccio, U.; Friemel, J.; Remde, H.; Fassnacht, M.; Pamporaki, C.; Eisenhofer, G.; Timmers, H. J. L. M.; Robledo, M.; Fliedner, S. M. J.; Wang, K.; Maurer, J.; Reul, A.; Zitzmann, K.; Bechmann, N.; Žygienė, G.; Richter, S.; Hantel, C.; Vetter, D.; Lehmann, K.; Mohr, H.; Pellegata, N. S.; Ullrich, M.; Pietzsch, J.; Ziegler, C. G.; Bornstein, S. R.; Kroiss, M.; Reincke, M.; Pacak, K.; Grossman, A. B.; Beuschlein, F.; Nölting, S.

Impedimetric Nanobiosensor for the Detection of SARS-CoV-2 Antigens and Antibodies

Sandoval Bojorquez, D. I.; Janićijević, Ž.; Palestina Romero, B.; Oliveros Mata, E. S.; Laube, M.; Feldmann, A.; Kegler, A.; Drewitz, L.; Fowley, C.; Pietzsch, J.; Faßbender, J.; Tonn, T.; Bachmann, M.; Baraban, L.

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Synthesis of [18F]FMISO, a hypoxia-specific imaging probe for PET, an overview from a radiochemist’s perspective

Knieß, T.; Zessin, J.; Mäding, P.; Kuchar, M.; Kiß, O.; Kopka, K.

Involved research facilities

  • PET-Center
  • ZRT

Cyclotron-based Production of 67Cu for Radionuclide Theranostics Via the 70Zn(p,α)67Cu Reaction

Brühlmann, S. A.; Walther, M.; Kreller, M.; Reissig, F.; Pietzsch, H.-J.; Knieß, T.; Kopka, K.

Solid-Phase Parallel Synthesis of Dual Histone Deacetylase-Cyclooxygenase Inhibitors

Bachmann, L. M.; Hanl, M.; Feller, F.; Sinatra, L.; Schöler, A.; Pietzsch, J.; Laube, M.; Hansen, F. K.

Carborane Analogues of Fenoprofen Exhibit Improved Antitumor Activity

Useini, L.; Mojić, M.; Laube, M.; Lönnecke, P.; Mijatović, S. S.; Maksimović-Ivanić, D.; Pietzsch, J.; Hey-Hawkins, E.

The Impact of Nε-Acryloyllysine Piperazides on the Conformational Dynamics of Transglutaminase 2

Heerwig, A.; Kick, A.; Sommerfeld, P.; Eimermacher, S.; Hartung, F.; Laube, M.; Fischer, D.; Pietzsch, H.-J.; Pietzsch, J.; Löser, R.; Mertig, M.; Pietsch, M.; Wodtke, R.

Involved research facilities

  • ZRT

In vitro Cytostatic Effect on Tumor Cells by Carborane-based Dual Cyclooxygenase-2 and 5-Lipoxygenase Inhibitors

Braun, S.; Paskas, S.; Laube, M.; George, S.; Hofmann, B.; Lönnecke, P.; Steinhilber, D.; Pietzsch, J.; Mijatović, S. S.; Maksimović-Ivanić, D.; Hey-Hawkins, E.

Microdialysis reveals anti-inflammatory effects of sulfated glycosaminoglycanes in the early phase of bone healing

Schulze, S.; Neuber, C.; Möller, S.; Pietzsch, J.; Schaser, K.-D.; Rammelt, S.

A self-assembled dynamic extracellular matrix-like hydrogel system with multi-scale structures for cell bioengineering applications

Xu, Y.; Rothe, R.; Voigt, D.; Sayed, A.; Huang, C.; Hauser, S.; Lee, P. W.; Cui, M.; Saenz, J. P.; Boccaccini, A. R.; Zheng, K.; Pietzsch, J.; Zhang, Y.

Enzymological characterization of ⁶⁴Cu-labeled neprilysin substrates and their application for modulating the renal clearance of targeted radiopharmaceuticals

Brandt, F.; Ullrich, M.; Wodtke, J.; Kopka, K.; Bachmann, M.; Löser, R.; Pietzsch, J.; Pietzsch, H.-J.; Wodtke, R.

Involved research facilities

  • ZRT

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Dipeptide-derived alkynes as potent and selective irreversible inhibitors of cysteine cathepsins

Behring, L.; Ruiz-Gomez, G.; Trapp, C.; Morales, M.; Wodtke, R.; Köckerling, M.; Kopka, K.; Pisabarro, M. T.; Pietzsch, J.; Löser, R.

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Epigenetic drugs in somatostatin type 2 receptor radionuclide theranostics and radiation transcriptomics in mouse pheochromocytoma models

Ullrich, M.; Richter, S.; Liers, J.; Drukewitz, S.; Friedemann, M.; Kotzerke, J.; Ziegler, C. G.; Nölting, S.; Kopka, K.; Pietzsch, J.

Anti-cancer prodrug cyclophosphamide exerts thrombogenic effects on human venous endothelial cells independent of CYP450 activation – relevance to thrombosis

Krüger-Genge, A.; Köhler, S.; Laube, M.; Haileka, V.; Lemm, S.; Majchrzak, K.; Kammerer, S.; Schulz, C.; Storsberg, J.; Pietzsch, J.; Küpper, J.-H.; Jung, F.

Significance of pulmonary endothelial injury and the role of cyclooxygenase-2 and prostanoid signaling

Nickl, R.; Hauser, S.; Pietzsch, J.; Richter, T.

2022

Towards personalized medicine: one chelator for imaging and therapy with lutetium-177 and actinium-225

Cieslik, P.; Kubeil, M.; Zarschler, K.; Ullrich, M.; Brandt, F.; Anger, K.; Wadepohl, H.; Kopka, K.; Bachmann, M.; Pietzsch, J.; Stephan, H.; Comba, P.

Involved research facilities

  • ZRT

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Case report: Incidentally discovered case of pheochromocytoma as a cause of long COVID-19 syndrome

Ziegler, C. G.; Riediger, C.; Gruber, M.; Kunath, C.; Ullrich, M.; Pietzsch, J.; Nölting, S.; Siepmann, T.; Bornstein, S. R.; Remde, H.; Constantinescu, G.

Exploring nitric oxide (NO)- releasing celecoxib derivatives as modulators of radioresponse in pheochromocytoma cells

Brandt, F.; Ullrich, M.; Seifert, V.; Haase-Kohn, C.; Richter, S.; Knieß, T.; Pietzsch, J.; Laube, M.

Development of a neurotensin-derived 68Ga-labeled PET ligand with high in vivo stability for imaging of NTS1 receptor-expressing tumors

Schindler, L.; Moosbauer, J.; Schmidt, D.; Spruss, T.; Grätz, L.; Lüdeke, S.; Hofheinz, F.; Meister, S.; Echtenacher, B.; Bernhardt, G.; Pietzsch, J.; Hellwig, D.; Keller, M.

Cyclam with a phosphinate-bis(phosphonate) pendant arm is a bone-targeting carrier of copper radionuclides

Pazderová, L.; Benešová, M.; Havlíčková, J.; Vojtíčková, M.; Kotek, J.; Lubal, P.; Ullrich, M.; Walther, M.; Schulze, S.; Neuber, C.; Rammelt, S.; Pietzsch, H.-J.; Pietzsch, J.; Kubíček, V.; Hermann, P.

Nanochips assisted peptide screening for clinical development of CAR-T cell immunotherapy

Anh Nguyen-Le, T.; Bartsch, T.; Wodtke, R.; Brandt, F.; Arndt, C.; Feldmann, A.; Isabel Sandoval Bojorquez, D.; Perez Roig, A.; Ibarlucea, B.; Lee, S.; Baek, C.-K.; Cuniberti, G.; Bergmann, R.; Puentes-Cala, E.; Andrés Soto, J.; T. Kurien, B.; Bachmann, M.; Baraban, L.

Long-term excessive dietary phosphate increases arterial blood pressure, activates the renin-angiotensin-aldosterone system, and stimulates sympathetic tone in mice

Latic, N.; Peitzsch, M.; Zupcic, A.; Pietzsch, J.; Erben, R. G.

Impact of sulfated hyaluronan on bone metabolism in diabetic Charcot neuroarthropathy and degenerative arthritis

Schulze, S.; Neuber, C.; Möller, S.; Hempel, U.; Hofbauer, L. C.; Schaser, K.-D.; Pietzsch, J.; Rammelt, S.

Combining Radiation- with Immunotherapy in Prostate Cancer: Influence of Radiation on T cells

Lindner, D.; Arndt, C.; Loureiro, L. R.; Feldmann, A.; Kegler, A.; Koristka, S.; Berndt, N.; Mitwasi, N.; Bergmann, R.; Frenz, M.; Bachmann, M.

1-(4-Fluorobenzoyl)-9H-carbazole

Laube, M.; König, J.; Köckerling, M.; Knieß, T.

Involved research facilities

  • ZRT

Investigation of radiotracer metabolic stability in vitro with CYP-overexpressing hepatoma cell lines

Lemm, S.; Köhler, S.; Wodtke, R.; Jung, F.; Küpper, J.-H.; Pietzsch, J.; Laube, M.

Targeting CD10 on B-Cell Leukemia Using the Universal CAR T-Cell Platform (UniCAR)

Mitwasi, N.; Arndt, C.; Loureiro, L. R.; Kegler, A.; Fasslrinner, F.; Berndt, N.; Bergmann, R.; HoˇRejší, V.; Rössig, C.; Bachmann, M.; Feldmann, A.

Development and functional characterization of a versatile radio-/immunotheranostic tool for prostate cancer management

Arndt, C.; Bergmann, R.; Striese, F.; Merkel, K.; Máthé, D.; Loureiro, L. R.; Mitwasi, N.; Kegler, A.; Fasslrinner, F.; González Soto, K. E.; Neuber, C.; Berndt, N.; Kovács, N.; Szöllősi, D.; Hegedűs, N.; Tóth, G.; Emmermann, J.-P.; Harikumar, K. B.; Kovacs, T.; Bachmann, M.; Feldmann, A.

Personalized drug testing in human pheochromocytoma/paraganglioma primary cultures

Wang, K.; Schütze, I.; Gulde, S.; Bechmann, N.; Richter, S.; Helm, J.; Lauseker, M.; Maurer, J.; Reul, A.; Spöttl, G.; Klink, B.; William, D.; Knösel, T.; Friemel, J.; Bihl, M.; Weber, A.; Fankhauser, M.; Schober, L.; Vetter, D.; Broglie Däppen, M.; Ziegler, C. G.; Ullrich, M.; Pietzsch, J.; Bornstein, S. R.; Lottspeich, C.; Kroiß, M.; Fassnacht, M.; Wenter, V.; Ladurner, R.; Hantel, C.; Reincke, M.; Eisenhofer, G.; Grossman, A. B.; Pacak, K.; Beuschlein, F.; Auernhammer, C. J.; Pellegata, N.; Nölting, S.

Application of a fluorescence anisotropy-based assay to quantify transglutaminase 2 activity in cell lysates

Hauser, S.; Sommerfeld, P.; Wodtke, J.; Hauser, C.; Schlitterlau, P.; Pietzsch, J.; Löser, R.; Pietsch, M.; Wodtke, R.

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Carboranyl analogues of mefenamic acid and their biological evaluation

Useini, L.; Mojic, M.; Laube, M.; Lönnecke, P.; Dahme, J.; Sárosi, M. B.; Mijatovic, S.; Maksimovic-Ivanic, D.; Pietzsch, J.; Hey-Hawkins, E.

A self-assembled matrix system for cell-bioengineering applications in different dimensions, scales, and geometries

Xu, Y.; Patino Gaillez, M.; Zheng, K.; Voigt, D.; Cui, M.; Kurth, T.; Xiao, L.; Rothe, R.; Hauser, S.; Lee, P. W.; Wieduwild, R.; Lin, W.; Bornhäuser, M.; Pietzsch, J.; Boccaccini, A. R.; Zhang, Y.

The role of transglutaminase 2 in the radioresistance of melanoma cells

Aepler, J.; Wodtke, J.; Wodtke, R.; Haase-Kohn, C.; Löser, R.; Pietzsch, J.; Hauser, S.

Therapeutic Potential of Nitric Oxide releasing Selective Estrogen Receptor Modulators (NO-SERMs) in Malignant Melanoma

Bechmann, N.; Calsina, B.; Richter, S.; Pietzsch, J.

“Clickable” albumin binders for modulating the tumor uptake of targeted radiopharmaceuticals

Brandt, F.; Ullrich, M.; Laube, M.; Kopka, K.; Bachmann, M.; Löser, R.; Pietzsch, J.; Pietzsch, H.-J.; van den Hoff, J.; Wodtke, R.

Involved research facilities

  • PET-Center

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Tumor irradiation in mice with a laser-accelerated proton beam

Kroll, F.; Brack, F.-E.; Bernert, C.; Bock, S.; Bodenstein, E.; Brüchner, K.; Cowan, T.; Gaus, L.; Gebhardt, R.; Helbig, U.; Karsch, L.; Kluge, T.; Kraft, S.; Krause, M.; Leßmann, E.; Masood, U.; Meister, S.; Metzkes-Ng, J.; Nossula, A.; Pawelke, J.; Pietzsch, J.; Püschel, T.; Reimold, M.; Rehwald, M.; Richter, C.; Schlenvoigt, H.-P.; Schramm, U.; Umlandt, M. E. P.; Ziegler, T.; Zeil, K.; Beyreuther, E.

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CRISPR/Cas9 mediated knockout of cyclooxygenase-2 gene inhibits invasiveness in A2058 melanoma cells

Haase-Kohn, C.; Laube, M.; Donat, C.; Belter, B.; Pietzsch, J.

2021

Radiolabeled Silicon-Rhodamines as Bimodal PET/SPECT-NIR Imaging Agents

Kanagasundaram, T.; Laube, M.; Wodtke, J.; Kramer, S. C.; Stadlbauer, S.; Pietzsch, J.; Kopka, K.

Solid-phase synthesis of selectively mono-fluorobenz(o)ylated polyamines as a basis for for the Development of 18F-Labeled Radiotracers

Wodtke, R.; Pietzsch, J.; Löser, R.

Involved research facilities

  • PET-Center

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Targeting acute myeloid leukemia using the RevCAR platform: a programmable, switchable and combinatorial strategy

Kittel-Boselli, E.; González Soto, K. E.; Loureiro, L. R.; Hoffmann, A.; Bergmann, R.; Arndt, C.; Koristka, S.; Mitwasi, N.; Kegler, A.; Bartsch, T.; Berndt, N.; Altmann, H.; Fasslrinner, F.; Bornhäuser, M.; Bachmann, M.; Feldmann, A.

And yet it moves: Oxidation of the Nuclear Autoantigen La/SS-B is the Driving Force for Nucleo-Cytoplasmic Shuttling

Berndt, N.; Bippes, C. C.; Michalk, I.; Bartsch, T.; Arndt, C.; Puentes-Cala, E.; Soto, J. A.; Loureiro, L. R.; Kegler, A.; Bachmann, D.; Gross, J. K.; Gross, T.; Kurien, B.; Scofield, T. R. H.; Farris, A. D.; James, J. A.; Bergmann, R.; Schmitz, M.; Feldmann, A.; Bachmann, M.

Modulation of γ-secretase activity by a carborane-based flurbiprofen analogue

Saretz, S.; Basset, G.; Useini, L.; Laube, M.; Pietzsch, J.; Draca, D.; Maksimović-Ivanić, D.; Trambauer, J.; Steiner, H.; Hey-Hawkins, E.

Conductive hydrogels with dynamic reversible networks for biomedical applications

Xu, Y.; Patino Gaillez, M.; Rothe, R.; Hauser, S.; Voigt, D.; Pietzsch, J.; Zhang, Y.

Two Be or Not Two Be: The Nuclear Autoantigen La/SS-B Is able to form Dimers and Oligomers in a Redox Dependent Manner

Berndt, N.; Bippes, C. C.; Michalk, I.; Bachmann, D.; Bachmann, J.; Puentes-Cala, E.; Bartsch, T.; Loureiro, L. R.; Kegler, A.; Bergmann, R.; Gross, J. K.; Gross, T.; Kurien, B. T.; Scofield, R. H.; Farris, A. D.; James, J. A.; Schmitz, M.; Fahmy, K.; Feldmann, A.; Arndt, C.; Bachmann, M.

Development of an 18F-labelled irreversible inhibitor of transglutaminase 2 as radiometric tool for quantitative expression profiling in cells and tissues

Wodtke, R.; Wodtke, J.; Hauser, S.; Laube, M.; Bauer, D.; Rothe, R.; Neuber, C.; Pietsch, M.; Kopka, K.; Pietzsch, J.; Löser, R.

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Convergent Synthesis of Diversified Reversible Network Leads to Liquid Metal-Containing Conductive Hydrogel Adhesives

Xu, Y.; Rothe, R.; Voigt, D.; Hauser, S.; Cui, M.; Miyagawa, T.; Patino Gaillez, M.; Kurth, T.; Bornhäuser, M.; Pietzsch, J.; Zhang, X.

Radiotherapy enhances uptake and efficacy of 90Y-cetuximab: A preclinical trial

Dietrich, A.; Andreeff, M.; Koi, L.; Bergmann, R.; Schubert, M.; Schreiner, L.; Löck, S.; Sihver, W.; Freudenberg, R.; Hering, S.; Pietzsch, H.-J.; Steinbach, J.; Kotzerke, J.; Baumann, M.; Krause, M.

Involved research facilities

  • PET-Center

Development of a ghrelin receptor inverse agonist for positron emission tomography

Bergmann, R.; Chollet, C.; Els-Heindl, S.; Ullrich, M.; Berndt, N.; Pietzsch, J.; MáThé, D.; Bachmann, M.; Beck-Sickinger, A. G.

Involved research facilities

  • PET-Center

Men who stare at bone: multimodal monitoring of bone healing

Schulze, S.; Rothe, R.; Neuber, C.; Hauser, S.; Ullrich, M.; Pietzsch, J.; Rammelt, S.

HIF2alpha-associated pseudohypoxia promotes radioresistance in pheochromocytoma: insights from 3D models

Seifert, V.; Richter, S.; Bechmann, N.; Bachmann, M.; Ziegler, C. G.; Pietzsch, J.; Ullrich, M.

Screening Arrays of Laminin Peptides on Modified Cellulose for Promotion of Adhesion of Primary Endothelial and Neural Precursor Cells

Wetzel, R.; Hauser, S.; Lin, W.; Berg, P.; Werner, C.; Pietzsch, J.; Kempermann, G.; Zhang, Y.

Response of endothelial cells to gelatin-based hydrogels

Krüger-Genge, A.; Hauser, S.; Neffe, A. T.; Liu, Y.; Lendlein, A.; Pietzsch, J.; Jung, F.

Immunocompatibility and non-thrombogenicity of gelatin-based hydrogels

Krüger-Genge, A.; Tondera, C.; Hauser, S.; Braune, S.; Görs, J.; Roch, T.; Klopfleisch, R.; Neffe, A. T.; Lendlein, A.; Pietzsch, J.; Jung, F.

Radiolabelled Cyclic Bisarylmercury: High Chemical and in vivo Stability for Theranostics

Gilpin, I. M.; Ullrich, M.; Wünsche, T.; Zarschler, K.; Lebeda, O.; Pietzsch, J.; Pietzsch, H.-J.; Walther, M.

A modular, injectable, non-covalently assembled hydrogel system features widescale tunable degradability for controlled release and tissue integration

Rothe, R.; Xu, Y.; Kuriakose Thomas, A.; Meister, S.; Zhang, Y.; Pietzsch, J.; Hauser, S.

2020

Telemedicine pre and post COVID-19: Lessons for commercialization based on previous use cases

Ferenczi, G. L.; Mahmood, A.; Bergmann, R.

  • Open Access Logo Journal of the International Society for Telemedicine and eHealth 8(2020), e8
    DOI: 10.29086/JISfTeH.8.e8

Suppression of Metastatic Melanoma Growth in Lung by Modulated Electro-Hyperthermia Monitored by a Minimally Invasive Heat Stress Testing Approach in Mice

Thomas, M. J.; Major, E.; Benedek, A.; Horvath, I.; Mathe, D.; Bergmann, R.; Szasz, A. M.; Krenacs, T.; Benyo, Z.

Involved research facilities

  • PET-Center

The pyrazolo[3,4-d]pyrimidine-based kinase inhibitor NVP-BHG712: Effects of regioisomers on tumor growth, perfusion, and hypoxia in EphB4-positive A375 melanoma xenografts

Neuber, C.; Tröster, A.; Löser, R.; Belter, B.; Schwalbe, H.; Pietzsch, J.

Three-dimensional cell culture systems in radiopharmaceutical cancer research

Doctor, A.; Seifert, V.; Ullrich, M.; Hauser, S.; Pietzsch, J.

HIF2α supports pro-metastatic behavior in pheochromocytomas/paragangliomas

Bechmann, N.; Moskopp, M. L.; Ullrich, M.; Calsina, B.; Wallace, P. W.; Richter, S.; Friedemann, M.; Langton, K.; Fliedner, S. M. J.; Timmers, H. J. L. M.; Nölting, S.; Beuschlein, F.; Fassnacht, M.; Preijbisz, A.; Pacak, K.; Ghayee, H. K.; Bornstein, S. R.; Dieterich, P.; Pietzsch, J.; Wielockx, B.; Robledo, M.; Qin, N.; Eisenhofer, G.

Development and In Vivo Application of a Water-Soluble Anticancer Copper Ionophore System Using a Temperature-Sensitive Liposome Formulation

Gaál, A.; Garay, T. M.; Horváth, I.; Máthé, D.; Szöllösi, D.; Veres, D. S.; Mbuotidem, J.; Kovacs, T.; Tóvári, J.; Bergmann, R.; Streli, C.; Szakács, G.; Mihály, J.; Varga, Z.; Szoboszlai, N.

Versatile chimeric antigen receptor platform for controllable and combinatorial T cell therapy

Feldmann, A.; Hoffmann, A.; Bergmann, R.; Koristka, S.; Berndt, N.; Arndt, C.; Loureiro, L. R.; Kittel-Boselli, E.; Mitwasi, N.; Kegler, A.; Lamprecht, C.; González Soto, K. E.; Bachmann, M.

The influence of different artificial extracellular matrix implant coatings on the regeneration of a critical size femur defect in rats

Förster, Y.; Schulze, S.; Penk, A.; Neuber, C.; Möller, S.; Hintze, V.; Scharnweber, D.; Schnabelrauch, M.; Pietzsch, J.; Huster, D.; Rammelt, S.

Recent insights in barium-131 as a diagnostic match for radium-223: cyclotron production, separation, labeling and imaging

Reissig, F.; Bauer, D.; Ullrich, M.; Kreller, M.; Pietzsch, J.; Mamat, C.; Kopka, K.; Pietzsch, H.-J.; Walther, M.

Metabolomics, machine learning and immunohistochemistry to predict succinate dehydrogenase mutational status in phaeochromocytomas and paragangliomas

Wallace, P. W.; Conrad, C.; Brückmann, S.; Pang, Y.; Caleiras, E.; Murakami, M.; Korpershoek, E.; Zhuang, Z.; Rapizzi, E.; Kroiss, M.; Gudziol, V.; Timmers, H. J. L. M.; Mannelli, M.; Pietzsch, J.; Beuschlein, F.; Pacak, K.; Robledo, M.; Klink, B.; Peitzsch, M.; Gill, A. J.; Tischler, A. S.; de Krijger, R. R.; Papathomas, T.; Aust, D.; Eisenhofer, G.; Richter, S.

Deuteration versus ethylation – strategies to improve the metabolic fate of a 18F-labeled celecoxib derivative

Laube, M.; Gassner, C.; Neuber, C.; Wodtke, R.; Ullrich, M.; Haase-Kohn, C.; Löser, R.; Köckerling, M.; Kopka, K.; Knieß, T.; Hey-Hawkins, E.; Pietzsch, J.

A radiopharmacologist's and radiochemist's view on targeting the Eph/ephrin receptor tyrosine kinase system

Neuber, C.; Belter, B.; Mamat, C.; Pietzsch, J.

Highly efficient targeting of EGFR-expressing tumor cells with UniCAR T cells via target modules based on Cetuximab®

Jureczek, J.; Feldmann, A.; Bergmann, R.; Arndt, C.; Berndt, N.; Koristka, S.; Loureiro, L. R.; Mitwasi, N.; Hoffmann, A.; Kegler, A.; Bartsch, T.; Bachmann, M.

Extended half-life target module for sustainable UniCAR T-cell treatment of STn-expressing cancers

Loureiro, L. R.; Feldmann, A.; Bergmann, R.; Koristka, S.; Berndt, N.; Máthé, D.; Hegedüs, N.; Szigeti, K.; Videira, P. A.; Bachmann, M.; Arndt, C.

Adjuvant drug-assisted bone healing: advances and challenges in drug delivery approaches

Rothe, R.; Hauser, S.; Neuber, C.; Laube, M.; Schulze, S.; Rammelt, S.; Pietzsch, J.

UniCAR T cell immunotherapy enables efficient elimination of radioresistant cancer cells

Arndt, C.; Loureiro, L. R.; Feldmann, A.; Jureczek, J.; Bergmann, R.; Máthé, D.; Hegedüs, N.; Berndt, N.; Koristka, S.; Metwasi, N.; Fasslrinner, F.; Lamprecht, C.; Kegler, A.; Hoffmann, A.; Bartsch, T.; Köseer, A. S.; Egan, G.; Schmitz, M.; Hořejší, V.; Krause, M.; Dubrovska, A.; Bachmann, M.

Synthesis, radiolabeling and first biological characterization of 18F-labeled xanthine derivatives for PET imaging of Eph receptors

Pretze, M.; Neuber, C.; Kinski, E.; Belter, B.; Köckerling, M.; Caflisch, A.; Steinbach, J.; Pietzsch, J.; Mamat, C.

Involved research facilities

  • PET-Center

Regulation of bone regeneration

Jung, F.; Pietzsch, J.

Carboranyl Derivatives of Rofecoxib with Cytostatic Activity Against Human Melanoma and Colon Cancer Cells

Buzharevski, A.; Paskas, S.; Sárosi, M.-B.; Laube, M.; Lönnecke, P.; Neumann, W.; Murganić, B.; Mijatović, S.; Maksimović-Ivanić, D.; Pietzsch, J.; Hey-Hawkins, E.

The sigma-1 receptor: potential role in the modulation of cellular radiation sensitivity

Belter, B.; Deuther-Conrad, W.; Hofheinz, F.; Bachmann, M.; Brust, P.; Pietzsch, J.

“UniCAR”-modified off-the-shelf NK-92 cells for targeting of GD2-expressing tumour cells

Mitwasi, N.; Feldmann, A.; Arndt, C.; Koristka, S.; Berndt, N.; Jureczek, J.; Loureiro, L.; Bergmann, R.; Máthé, D.; Hegedüs, N.; Kovács, T.; Zhang, C.; Oberoi, P.; Jäger, E.; Seliger, B.; Rössig, C.; Temme, A.; Eitler, J.; Tonn, T.; Schmitz, M.; Hassel, J.; Jäger, D.; Wels, W.; Bachmann, M.

Active Targeting of Dendritic Polyglycerols for Diagnostic Cancer Imaging

Kritee, P.; Neuber, C.; Zarschler, K.; Wodtke, J.; Meister, S.; Rainer, H.; Pietzsch, J.; Stephan, H.

Involved research facilities

  • PET-Center

Versatile Bispidine-based Bifunctional Chelators for 64CuII-Labelling of Biomolecules

Singh, G.; Zarschler, K.; Hunoldt, S.; Santana Martinez, I. I.; Rühl, C.; Matterna, M.; Bergmann, R.; Mathe, D.; Hegedüs, N.; Bachmann, M.; Comba, P.; Stephan, H.

Involved research facilities

  • PET-Center

Ultrasmall silicon nanoparticles as a promising platform for multimodal imaging

Singh, G.; Ddungu, J. L. Z.; Licciardello, N.; Bergmann, R.; de Cola, L.; Stephan, H.

Involved research facilities

  • PET-Center

2019

Introduction of the New Center for Radiopharmaceutical Cancer Research at Helmholtz-Zentrum Dresden-Rossendorf

Kreller, M.; Pietzsch, H.-J.; Walther, M.; Tietze, H.; Kaever, P.; Knieß, T.; Füchtner, F.; Steinbach, J.; Preusche, S.

Synthesis and cyclooxygenase inhibition of sulfonamide-substituted (dihydro)pyrrolo[3,2,1-hi]indoles and their potential prodrugs

Laube, M.; Gassner, C.; Knieß, T.; Pietzsch, J.

Characterization of Tissue Transglutaminase as a Potential Biomarker for Tissue Response toward Biomaterials

Hauser, S.; Wodtke, R.; Tondera, C.; Wodtke, J.; Neffe, A. T.; Hampe, J.; Lendlein, A.; Löser, R.; Pietzsch, J.

Current management of pheochromocytoma/paraganglioma: A guide for the practicing clinician in the era of precision medicine

Nölting, S.; Ullrich, M.; Pietzsch, J.; Ziegler, C. G.; Eisenhofer, G.; Grossman, A.; Pacak, K.

Conventional CARs versus modular CARs

Feldmann, A.; Arndt, C.; Koristka, S.; Berndt, N.; Bergmann, R.; Bachmann, M.

A theranostic PSMA ligand for PET imaging and retargeting of T cells expressing the universal chimeric antigen receptor UniCAR

Arndt, C.; Feldmann, A.; Koristka, S.; Schäfer, M.; Bergmann, R.; Metwasi, N.; Berndt, N.; Bachmann, D.; Kegler, A.; Schmitz, M.; Puentes-Cala, E.; Soto, J. A.; Ehninger, G.; Pietzsch, J.; Liolios, C.; Wunderlich, G.; Kotzerke, J.; Kopka, K.; Bachmann, M.

Biomaterials in repairing rat femoral defects: in vivo insights from small animal positron emission tomography/computed tomography (PET/CT) studies

Neuber, C.; Schulze, S.; Förster, Y.; Hofheinz, F.; Wodke, J.; Möller, S.; Schnabelrauch, M.; Hintze, V.; Scharnweber, D.; Rammelt, S.; Pietzsch, J.

Theranostic CAR T cell targeting: A brief review

Arndt, C.; Bachmann, M.; Bergmann, R.; Berndt, N.; Feldmann, A.; Koristka, S.

Instant kit preparation of 68Ga-radiopharmaceuticals via the hybrid chelator DATA: clinical translation of [68Ga]Ga-DATA-TOC

Sinnes, J. P.; Nagel, J.; Waldron, B. P.; Maina, T.; Nock, B. A.; Bergmann, R. K.; Ullrich, M.; Pietzsch, J.; Bachmann, M.; Baum, P. B.; Rösch, F.

Cytocompatible, Injectable, and Electroconductive Soft Adhesives with Hybrid Covalent/Noncovalent Dynamic Network

Xu, Y.; Patsis, P. A.; Hauser, S.; Voigt, D.; Rothe, R.; Günther, M.; Cui, M.; Yang, X.; Wieduwild, R.; Eckert, K.; Neinhuis, C.; Akbar, T. F.; Minev, I. R.; Pietzsch, J.; Zhang, J.

T cells engrafted with a UniCAR 28/ζ outperform UniCAR BB/ζ-transduced T cells in the face of regulatory T cell-mediated immunosuppression

Kegler, A.; Koristka, S.; Bergmann, R.; Berndt, N.; Arndt, C.; Feldmann, A.; Hoffmann, A.; Bornhäuser, M.; Schmitz, M.; Bachmann, M.

Nitric oxide-releasing selective estrogen receptor modulators (NO-SERMs): a bifunctional approach to improve the therapeutic index

Bechmann, N.; Knieß, T.; Pietzsch, J.

Targeting Cyclooxygenase-2 in Pheochromocytoma and Paraganglioma: Focus on Genetic Background

Ullrich, M.; Richter, S.; Seifert, V.; Hauser, S.; Calsina, B.; Martínez-Montes, A. M.; Ter Laak, M.; Ziegler, C. G.; Timmers, H.; Eisenhofer, G.; Robledo, M.; Pietzsch, J.

Adjuvant drug-assisted bone healing: Part III – Further strategies for local and systemic modulation

Rothe, R.; Schulze, S.; Neuber, C.; Hauser, S.; Rammelt, S.; Pietzsch, J.

Adjuvant drug-assisted bone healing: Part II – Modulation of angiogenesis

Rothe, R.; Schulze, S.; Neuber, C.; Hauser, S.; Rammelt, S.; Pietzsch, J.

Adjuvant drug-assisted bone healing: Part I – Modulation of inflammation

Rothe, R.; Schulze, S.; Neuber, C.; Hauser, S.; Rammelt, S.; Pietzsch, J.

Impact of Extrinsic and Intrinsic Hypoxia on Catecholamine Biosynthesis in Absence or Presence of Hif2α in Pheochromocytoma Cells

Bechmann, N.; Poser, I.; Seifert, V.; Greunke, C.; Ullrich, M.; Qin, N.; Walch, A.; Peitzsch, M.; Robledo, M.; Pacak, K.; Pietzsch, J.; Richter, S.; Eisenhofer, G.

Carboranyl analogues of ketoprofen with cytostatic activity against human melanoma and colon cancer cell lines

Buzharevski, A.; Paskas, S.; Laube, M.; Lönnecke, P.; Neumann, W.; Murganic, B.; Mijatovic, S.; Maksimovic-Ivanic, D.; Pietzsch, J.; Hey-Hawkins, E.

An oligo-His-tag of a targeting module does not influence its biodistribution and the retargeting capabilities of UniCAR T cells

Jureczek, J.; Bergmann, R.; Berndt, N.; Koristka, S.; Kegler, A.; Puentes-Cala, E.; Soto, J. A.; Arndt, C.; Bachmann, M.; Feldmann, A.

Limited importance of EphrinA1–ligand, Src kinase, and focal adhesion kinase in EphA2-mediated regulation of metastasis in Mel-Juso and A375 human melanoma cells

Neuber, C.; Herwig, N.; Pietzsch, J.; Belter, B.

Regulation of A375 melanoma cell adhesion and migration by EphB4 and EphrinB2 –insights from co-culture experiments

Neuber, C.; Laube, M.; Mamat, C.; Belter, B.; Pietzsch, J.

  • Journal of Cellular Biotechnology 5(2019)1, 27-42
    DOI: 10.3233/JCB-189011
    ISSN: 2352-3689

Radiochemical and radiopharmacological characterization of a 64Cu-labeled α-MSH analog conjugated with different chelators

Gao, F.; Sihver, W.; Bergmann, R.; Walther, M.; Stephan, H.; Belter, B.; Neuber, C.; Haase-Kohn, C.; Bolzati, C.; Pietzsch, J.; Pietzsch, H.-J.

Involved research facilities

  • PET-Center

Fluorescent Mouse Pheochromocytoma Spheroids Expressing Hypoxia-Inducible Factor 2 alpha: Morphologic and Radiopharmacologic Characterization

Seifert, V.; Liers, J.; Kniess, T.; Richter, S.; Bechmann, N.; Feldmann, A.; Bachmann, M.; Eisenhofer, G.; Pietzsch, J.; Ullrich, M.

Carboranyl Analogues of Celecoxib with Potent Cytostatic Activity against Human Melanoma and Colon Cancer Cell Lines

Buzharevski, A.; Paskas, S.; Sárosi, M. B.; Laube, M.; Lönnecke, P.; Neumann, W.; Mijatovic, S.; Maksimovic-Ivanic, D.; Pietzsch, J.; Hey-Hawkins, E.

Fluorine-18 labeling of S100 proteins for small animal positron emission tomography

Laube, M.; Kniess, T.; Neuber, C.; Haase-Kohn, C.; Pietzsch, J.

Involved research facilities

  • PET-Center

Synthesis and preliminary radiopharmacological characterisation of an 11C-labelled azadipeptide nitrile as potential PET tracer for imaging of cysteine cathepsins

Laube, M.; Frizler, M.; Wodtke, R.; Neuber, C.; Belter, B.; Kniess, T.; Bachmann, M.; Gütschow, M.; Pietzsch, J.; Löser, R.

Synthesis, 18F-labelling and radiopharmacological characterisation of the C-terminal 30mer of Clostridium perfringens enterotoxin as a potential claudin-targeting peptide

Löser, R.; Bader, M.; Kuchar, M.; Wodtke, R.; Lenk, J.; Wodtke, J.; Kuhne, K.; Bergmann, R.; Haase-Kohn, C.; Urbanová, M.; Steinbach, J.; Pietzsch, J.

One-pot Cascade Synthesis of Pyrazole-based Isosteres of Valdecoxib by a [3+2] Cycloaddition/[1,5] Sigmatropic Rearrangement Sequence and Evaluation of their COX Inhibitory Activity

Roscales, S.; Bechmann, N.; Pietzsch, J.; Kniess, T.

Involved research facilities

  • PET-Center

Anti-CAR engineered T cells for epitope-based elimination of autologous CAR T cells

Koristka, S.; Ziller-Walter, P.; Bergmann, R.; Arndt, C.; Feldmann, A.; Kegler, A.; Cartellieri, M.; Ehninger, A.; Ehninger, G.; Bornhäuser, M.; Bachmann, M.

Access to 18F-labelled isoxazoles by Ruthenium-promoted 1,3-dipolar cycloaddition of 4-[18F]fluoro-N-hydroxybenzimidoyl chloride with alkynes.

Roscales, S.; Kniess, T.

Involved research facilities

  • PET-Center

2018

Evaluation of Brain Nuclear Medicine Imaging Tracers in a Murine Model of Sepsis-Associated Encephalopathy

Szöllősi, D.; Hegedűs, N.; Veres, D. S.; Futó, I.; Horváth, I.; Kovács, N.; Martinecz, B.; Dénes, Á.; Seifert, D.; Bergmann, R.; Lebeda, O.; Varga, Z.; Kaleta, Z.; Szigeti, K.; Máthé, D.

Involved research facilities

  • PET-Center

Multimodal PET/MRI Imaging Results Enable Monitoring the Side Effects of Radiation Therapy.

Kovács, N.; Szigeti, K.; Hegedűs, N.; Horváth, I.; Veres, D. S.; Bachmann, M.; Bergmann, R.; Máthé, D.

Diverse Effects of Phospholipase A2 Receptor Expression on LNCaP and PC-3 Prostate Cancer Cell Growth in vitro and in vivo

Friedemann, M.; Nacke, B.; Hagelgans, A.; Jandeck, C.; Bechmann, N.; Ullrich, M.; Belter, B.; Neuber, C.; Sukocheva, O.; Pietzsch, J.; Menschikowski, M.

Improved Conjugation, 64-Cu Radiolabeling, in Vivo Stability, and Imaging Using Nonprotected Bifunctional Macrocyclic Ligands: Bis(Phosphinate) Cyclam (BPC) Chelators

David, T.; Hlinová, V.; Kubíček, V.; Bergmann, R.; Striese, F.; Berndt, N.; Szöllösi, D.; Hegedus, N.; Mathe, D.; Bachmann, M.; Pietzsch, H.-J.; Hermann, P.

Involved research facilities

  • PET-Center

Synthesis, characterization and initial biological evaluation of [⁹⁹ᵐTc]Tc-tricarbonyl labeled DPA-α-MSH peptide derivatives for potential melanoma imaging

Gao, F.; Sihver, W.; Bergmann, R.; Belter, B.; Bolzati, C.; Salvarese, N.; Steinbach, J.; Pietzsch, J.; Pietzsch, H.-J.

Involved research facilities

  • PET-Center

Exploring pitfalls of 64Cu‑labeled EGFR‑targeting peptide GE11 as a potential PET tracer

Striese, F.; Sihver, W.; Gao, F.; Bergmann, R.; Walther, M.; Pietzsch, J.; Steinbach, J.; Pietzsch, H.-J.

Involved research facilities

  • PET-Center

Development of a novel target module redirecting UniCAR T cells to Sialyl Tn-expressing tumor cells

Loureiro, L.; Feldmann, A.; Bergmann, R.; Koristka, S.; Berndt, N.; Arndt, C.; Pietzsch, J.; Novo, C.; Videira, P.; Bachmann, M.

Strain-specific metastatic phenotypes in pheochromocytoma allograft mice

Ullrich, M.; Liers, J.; Peitzsch, M.; Feldmann, A.; Bergmann, R.; Sommer, U.; Richter, S.; Bornstein, S. R.; Bachmann, M.; Eisenhofer, G.; Ziegler, C. G.; Pietzsch, J.

Involved research facilities

  • PET-Center

From mono- to bivalent: improving theranostic properties of target modules for redirection of UniCAR T cells against EGFR-expressing tumor cells in vitro and in vivo

Albert, S.; Arndt, C.; Koristka, S.; Berndt, N.; Bergmann, R.; Feldmann, A.; Schmitz, M.; Pietzsch, J.; Steinbach, J.; Bachmann, M.

Nε-Acryloyllysine piperazides as irreversible inhibitors of transglutaminase 2 – synthesis, structure-activity relationships and pharmacokinetic profiling

Wodtke, R.; Hauser, C.; Ruiz-Gómez, G.; Jäckel, E.; Bauer, D.; Lohse, M.; Wong, A.; Pufe, J.; Ludwig, F.-A.; Fischer, S.; Hauser, S.; Greif, D.; Pisabarro, M. T.; Pietzsch, J.; Pietsch, M.; Löser, R.

Biodistribution studies of ultrasmall silicon nanoparticles and carbon dots in experimental rats and tumor mice

Licciardello, N.; Hunoldt, S.; Bergmann, R.; Singh, G.; Mamat, C.; Faramus, A.; Ddungu, J. L. Z.; Silvestrini, S.; Maggini, M.; de Cola, L.; Stephan, H.

Involved research facilities

  • PET-Center

Overexpression of receptor tyrosine kinase EphB4 triggers tumor growth and hypoxia in A375 melanoma xenografts: insights from multitracer small animal imaging experiments

Neuber, C.; Belter, B.; Meister, S.; Hofheinz, F.; Bergmann, R.; Pietzsch, H.-J.; Pietzsch, J.

Bridging from Brain to Tumor imaging: (S)- and (R)-[18F]Fluspidine for investigation of Sigma-1 Receptors in Tumor-bearing Mice

Kranz, M.; Bergmann, R.; Kniess, T.; Belter, B.; Neuber, C.; Cai, Z.; Deng, G.; Fischer, S.; Steinbach, J.; Zhou, J.; Huang, H.; Brust, P.; Deuther-Conrad, W.; Pietzsch, J.

Involved research facilities

  • PET-Center

Causative treatment of acid aspiration induced acute lung injury – recent trends from animal experiments and critical perspective

Gramatté, J.; Pietzsch, J.; Bergmann, R.; Richter, T.

Involved research facilities

  • PET-Center

Engrafting human regulatory T cells with a flexible modular chimeric antigen receptor technology

Koristka, S.; Kegler, A.; Bergmann, R.; Arndt, C.; Feldmann, A.; Albert, S.; Cartellieri, M.; Ehninger, A.; Ehninger, G.; Middeke, J. M.; Bornhäuser, M.; Schmitz, M.; Pietzsch, J.; Akgün, K.; Ziemssen, T.; Steinbach, J.; Bachmann, M. P.

Evaluation of fluorine-18-labelled alpha1(I)-N-telopeptide analogues as substrate-based radiotracers for PET imaging of melanoma-associated lysyl oxidase

Kuchar, M.; Neuber, C.; Belter, B.; Bergmann, R.; Lenk, J.; Wodtke, R.; Kniess, T.; Steinbach, J.; Pietzsch, J.; Löser, R.

Novel Valdecoxib Derivates by Ruthenium-catalyzed 1,3-Dipolar Cycloaddition of Nitrile Oxides with Alkynes - Synthesis and COX-2 Inhibition Affinity.

Roscales, S.; Bechmann, N.; Weiss, D. H.; Köckerling, M.; Pietzsch, J.; Kniess, T.

Involved research facilities

  • PET-Center

2017

An orthotopic xenograft model for high-risk non-muscle invasive bladder cancer in mice: influence of mouse strain, tumor cell count, dwell time and bladder pretreatment

Huebner, D.; Rieger, C.; Bergmann, R.; Ullrich, M.; Meister, S.; Toma, M.; Wiedemuth, R.; Temme, A.; Novotny, V.; Wirth, M. P.; Bachmann, M.; Pietzsch, J.; Fuessel, S.

Involved research facilities

  • PET-Center

Nitric oxide-releasing selective cyclooxygenase-2 inhibitors as promising radiosensitizers in melanoma cells in vitro

Bechmann, N.; Hauser, S.; Hofheinz, F.; Kniess, T.; Pietzsch, J.

Involved research facilities

  • PET-Center
  • Open Access Logo Annals of Radiation Therapy and Oncology 1(2017)2, 1010

Novel Radiolabeled Bisphosphonates for PET Diagnosis and Endoradiotherapy of Bone Metastases

Pfannkuchen, N.; Meckel, M.; Bergmann, R.; Bachmann, M.; Bal, C.; Sathekge, M.; Mohnike, W.; Baum, R. P.; Rösch, F.

Biological characterization of novel nitroimidazole-peptide conjugates in vitro and in vivo.

Bergmann, R.; Splith, K.; Pietzsch, J.; Bachmann, M.; Neundorf, I.

Characterization of a switchable chimeric antigen receptor platform in a pre-clinical solid tumor model

Bejestani, E. P.; Cartellieri, M.; Bergmann, R.; Ehninger, A.; Loff, S.; Kramer, M.; Spehr, J.; Dietrich, A.; Feldmann, A.; Albert, S.; Wermke, M.; Baumann, M.; Krause, M.; Bornhäuser, M.; Ehninger, G.; Bachmann, M.; von Bonin, M.

Retargeting of UniCAR T cells with an in vivo synthesized target module directed against CD19 positive tumor cells

Bachmann, D.; Aliperta, R.; Bergmann, R.; Feldmann, A.; Koristka, S.; Arndt, C.; Loff, S.; Welzel, P. B.; Albert, S.; Kegler, A.; Ehninger, A.; Cartellieri, M.; Ehninger, G.; Bornhäuser, M.; von Bonin, M.; Werner, C.; Pietzsch, J.; Steinbach, J.; Bachmann, M.

Development of novel target modules for retargeting of UniCAR T cells to GD2 positive tumor cells

Mitwasi, N.; Feldmann, A.; Bergmann, R.; Berndt, N.; Arndt, C.; Koristka, S.; Kegler, A.; Jureczek, J.; Hoffmann, A.; Ehninger, A.; Cartellieri, M.; Albert, S.; Rössig, C.; Ehninger, G.; Pietzsch, J.; Steinbach, J.; Bachmann, M.

99mTechnetium-based Small Molecule Radiopharmaceuticals and Radiotracers Targeting Inflammation and Infection

Kniess, T.; Laube, M.; Wüst, F.; Pietzsch, J.

Involved research facilities

  • PET-Center

Preparation of a novel radiotracer targeting the EphB4 receptor via radiofluorination using spiro azetidinium salts as precursor

Wiemer, J.; Steinbach, J.; Pietzsch, J.; Mamat, C.

Involved research facilities

  • PET-Center

Surface charge and particle size determine the metabolic fate of dendritic polyglycerols

Pant, K.; Pufe, J.; Zarschler, K.; Bergmann, R.; Steinbach, J.; Reimann, S.; Haag, R.; Pietzsch, J.; Stephan, H.

Involved research facilities

  • PET-Center

A novel nanobody-based target module for retargeting of T lymphocytes to EGFR-expressing cancer cells via the modular UniCAR platform

Albert, S.; Arndt, C.; Feldmann, A.; Bergmann, R.; Bachmann, D.; Koristka, S.; Ludwig, F.; Ziller-Walter, P.; Kegler, A.; Gärtner, S.; Schmitz, M.; Ehninger, A.; Cartellieri, M.; Ehninger, G.; Pietzsch, H.-J.; Pietzsch, J.; Steinbach, J.; Bachmann, M.

A novel tumor pretargeting system based on complementary L-configured oligonucleotides

Schubert, M.; Bergmann, R.; Förster, C.; Sihver, W.; Vonhoff, S.; Klussmann, S.; Bethge, L.; Walther, M.; Schlesinger, J.; Pietzsch, J.; Steinbach, J.; Pietzsch, H.-J.

Involved research facilities

  • PET-Center

Distribution and kinetics of the Kv1.3-blocking peptide HsTX1[R14A] in experimental rats

Bergmann, R.; Kubeil, M.; Zarschler, K.; Chhabra, S.; Tajhya, R. B.; Beeton, C.; Pennington, M. W.; Bachmann, M.; Norton, R. S.; Stephan, H.

Involved research facilities

  • PET-Center

In vivo examination of an injectable hydrogel system crosslinked by peptide-oligosaccharide interaction in immunocompetent nude mice

Tondera, C.; Wieduwild, R.; Röder, E.; Werner, C.; Zhang, Y.; Pietzsch, J.

Development of Fluorinated Non-Peptidic Ghrelin Receptor Ligands for Potential Use in Molecular Imaging

Moldovan, R.-P.; Els-Heindl, S.; Worm, D. J.; Kniess, T.; Kluge, M.; Beck-Sickinger, A. G.; Deuther-Conrad, W.; Krügel, U.; Brust, P.

Retargeting of T lymphocytes to PSCA- or PSMA positive prostate cancer cells using the novel modular chimeric antigen receptor platform technology “UniCAR”

Feldmann, A.; Arndt, C.; Bergmann, R.; Loff, S.; Cartellieri, M.; Bachmann, D.; Aliperta, R.; Hetzenecker, M.; Ludwig, F.; Albert, S.; Ziller-Walter, P.; Kegler, A.; Koristka, S.; Gärtner, S.; Schmitz, M.; Ehninger, A.; Ehninger, G.; Pietzsch, J.; Steinbach, J.; Bachmann, M.

Involved research facilities

  • PET-Center

The Why and How of Amino Acid Analytics in Cancer Diagnostics and Therapy

Manig, F.; Kuhne, K.; von Neubeck, C.; Schwarzenbolz, U.; Yu, Z.; Kessler, B. M.; Pietzsch, J.; Kunz-Schughart, L. A.

Human endothelial cell models in biomaterial research

Hauser, S.; Jung, F.; Pietzsch, J.

Hydrous 18F-fluoroethylation – leaving off the azeotropic drying

Kniess, T.; Laube, M.; Steinbach, J.

Involved research facilities

  • PET-Center

Cryogel-Supported Stem Cell Factory for Customized Sustained Release of Bispecific Antibodies for Cancer Immunotherapy

Aliperta, R.; Welzel, P. B.; Bergmann, R.; Freudenberg, R.; Berndt, N.; Feldmann, A.; Arndt, C.; Koristka, S.; Stanzione, M.; Cartellieri, M.; Ehninger, A.; Ehninger, G.; Werner, C.; Pietzsch, J.; Steinbach, J.; Bornhäuser, M.; Bachmann, M.

Involved research facilities

  • PET-Center

Insights into binding of S100 proteins to scavenger receptors: class B scavenger receptor CD36 binds S100A12 with high affinity

Tondera, C.; Laube, M.; Pietzsch, J.

Involved research facilities

  • PET-Center

2016

Radiomics-based differentiation of lung disease models generated by polluted air based on X-ray computed tomography data

Szigeti, K.; Szabó, T.; Korom, C.; Ilona, C.; Horváth, I.; Veres, D. S.; Gyöngyi, Z.; Karlinger, K.; Bergmann, R.; Pócsik, M.; Budán, F.; Máthé, D.

Involved research facilities

  • PET-Center

Development of a F-18-labeled Diaryl-Substituted Dihydropyrrolo[3,2,1-hi]indole as Potential Probe for Functional Imaging of Cyclooxygenase-2 with PET

Gassner, C.; Neuber, C.; Laube, M.; Bergmann, R.; Kniess, T.; Pietzsch, J.

Involved research facilities

  • PET-Center

Gelatin-based hydrogel degradation and tissue interaction in vivo: insights from multimodal preclinical imaging in immunocompetent nude mice

Tondera, C.; Ullm, S.; Krüger-Genge, A.; Jung, F.; Neffe, A. T.; Lendlein, A.; Klopfleisch, R.; Steinbach, J.; Neuber, C.; Pietzsch, J.

Zwitterionic polymer-coated ultrasmall superparamagnetic iron oxide nanoparticles with low protein interaction and high biocompatibility

Pombo-García, K.; Weiss, S.; Zarschler, K.; Ang, C.-S.; Hübner, R.; Pufe, J.; Meister, S.; Seidel, J.; Pietzsch, J.; Spiccia, L.; Stephan, H.; Graham, B.

Extracellular S100A4 affects endothelial cell integrity and stimulates transmigratory behavior of human A375 melanoma cells

Herwig, N.; Belter, B.; Pietzsch, J.

Synthesis and kinetic characterisation of water-soluble fluorogenic acyl donors for transglutaminase 2

Wodtke, R.; Schramm, G.; Pietzsch, J.; Pietsch, M.; Löser, R.

Multimodal Somatostatin Receptor Theranostics Using [64Cu]Cu-/[177Lu]Lu-DOTA-(Tyr3)octreotate and AN-238 in a Mouse Pheochromocytoma Model.

Ullrich, M.; Bergmann, R.; Peitzsch, M.; Zenker, E.; Cartellieri, M.; Bachmann, M.; Ehrhart-Bornstein, M.; Block, N.; Schally, A.; Eisenhofer, G.; Bornstein, S.; Pietzsch, J.; Ziegler, C.

Involved research facilities

  • PET-Center

Development of antioxidant COX-2 inhibitors as radioprotective agents for radiation therapy – a hypothesis-driven review

Laube, M.; Kniess, T.; Pietzsch, J.

5-Chloro-1-phenylpentan-1-one

Bechmann, N.; Kniess, T.; Pietzsch, J.; König, J.; Köckerling, M.

Involved research facilities

  • PET-Center

177Lu-labelled macrocyclic bisphosphonates for targeting bone metastasis in cancer treatment

Bergmann, R.; Meckel, M.; Kubicek, V.; Pietzsch, J.; Steinbach, J.; Hermann, P.; Rösch, F.

Involved research facilities

  • PET-Center

Radiopharmacological characterization of 64Cu-labeled α-MSH analogs for potential use in imaging of malignant melanoma

Gao, F.; Sihver, W.; Jurischka, C.; Bergmann, R.; Haase-Kohn, C.; Belter, B.; Steinbach, J.; Carta, D.; Bolzati, C.; Calderan, A.; Pietzsch, J.; Pietzsch, H.-J.

Interaction of extracellular S100A4 with RAGE prompts prometastatic activation of A375 melanoma cells

Herwig, N.; Belter, B.; Wolf, S.; Haase-Kohn, C.; Pietzsch, J.

Involved research facilities

  • PET-Center

2015

Protective effects of 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitors on oxidative modification of human low density lipoproteins in vitro

Pietzsch, J.; Laube, M.; Bechmann, N.; Pietzsch, F.-J.; Kniess, T.

Controlled immobilization of His-tagged proteins for protein-ligand interaction experiments using Ni2+-NTA layer on glass surfaces

Cherkouk, C.; Rebohle, L.; Lenk, J.; Keller, A.; Ou, X.; Laubec, M.; Neuber, C.; Haase-Kohn, C.; Pietzsch, J.; Skorupa, W.

Involved research facilities

Related publications

Influence of irradiation on release of endothelial microparticles (EMP) in vitro

Neuber, C.; Pufe, J.; Pietzsch, J.

Involved research facilities

  • PET-Center

18F-Labeled 1,4-Dioxa-8-azaspiro[4.5]decane Derivative: Synthesis and Biological Evaluation of a σ1 Receptor Radioligand with Low Lipophilicity as Potent Tumor Imaging Agent

Xie, F.; Bergmann, R.; Kniess, T.; Deuther-Conrad, W.; Mamat, C.; Neuber, C.; Liu, B.; Steinbach, J.; Brust, P.; Pietzsch, J.; Jia, H.

Involved research facilities

  • PET-Center

2-[18F]Fluoroethyl tosylate - a versatile tool for building 18F-based radiotracers for positron emission tomography

Knieß, T.; Laube, M.; Brust, P.; Steinbach, J.

Involved research facilities

  • PET-Center

Novel (pyrazolyl)benzenesulfonamides with a nitric oxide-releasing moiety as selective cyclooxygenase-2 inhibitors

Bechmann, N.; Kniess, T.; Köckerling, M.; Pigorsch, A.; Steinbach, J.; Pietzsch, J.

Involved research facilities

  • PET-Center

Rational design of dual peptides targeting ghrelin and Y2 receptors to regulate food intake and body weight

Kilian, T. M.; Klöting, N.; Bergmann, R.; Els-Heindl, S.; Babilon, S.; Clément-Ziza, M.; Zhang, Y.; Beck-Sickinger, A. G.; Chollet, C.

Involved research facilities

  • PET-Center

In vivo Demonstration of an Active Tumor Pretargeting Approach with Peptide Nucleic Acid Bioconjugates as Complementary System

Leonidova, A.; Foerster, C.; Zarschler, K.; Schubert, M.; Pietzsch, H.-J.; Steinbach, J.; Bergmann, R.; Metzler-Nolte, N.; Stephan, H.; Gasser, G.

Involved research facilities

  • PET-Center

Cysteine cathepsins: their role in tumor progression and recent trends in the development of imaging probes

Löser, R.; Pietzsch, J.

Involved research facilities

  • PET-Center

Copper(II) cyclam complexes with N-propionic acid pendant arms

Kubeil, M.; Zarschler, K.; Pietzsch, J.; Kraus, W.; Comba, P.; Stephan, H.

Involved research facilities

  • PET-Center

Novel indole-based sigma-2 receptor ligands: synthesis, structure–affinity relationship and antiproliferative activity

Xie, F.; Kniess, T.; Neuber, C.; Deuther-Conrad, W.; Mamat, C.; Liebermann, B. P.; Liu, B.; Mach, R. H.; Brust, P.; Steinbach, J.; Pietzsch, J.; Jia, H.

Involved research facilities

  • PET-Center

Synthesis and Biodistribution Studies of 3H- and 64Cu-labeled Dendritic Polyglycerol and Dendritic Polyglycerol Sulfate

Pant, K.; Gröger, D.; Bergmann, R.; Pietzsch, J.; Steinbach, J.; Graham, B.; Spiccia, L.; Berthon, F.; Czarny, B.; Devel, L.; Dive, V.; Stephan, H.; Haag, R.

Involved research facilities

  • PET-Center

Development of indazolylpyrimidine derivatives as high-affine EphB4 receptor ligands and potential PET-radiotracers

Ebert, K.; Wiemer, J.; Caballero, J.; Köckerling, M.; Steinbach, J.; Pietzsch, J.; Mamat, C.

Involved research facilities

  • PET-Center

Reduced pulmonary blood flow in regions of injury 2 hours after acid aspiration in rats

Richter, T.; Bergmann, R.; Musch, G.; Pietzsch, G.; Koch, T.

Involved research facilities

  • PET-Center

Optical imaging of COX-2: Studies on an autofluorescent 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitor.

Tondera, C.; Ullm, S.; Laube, M.; Meister, S.; Neuber, C.; Mosch, B.; Kniess, T.; Pietzsch, J.

Involved research facilities

  • PET-Center

Cyclopeptides containing the DEKS motif as conformationally restricted collagen telopeptide analogues: synthesis and conformational analysis

Wodtke, R.; Ruiz-Gómez, G.; Kuchar, M.; Pisabarro, M. T.; Novotná, P.; Urbanová, M.; Steinbach, J.; Pietzsch, J.; Löser, R.

Involved research facilities

  • PET-Center

Diaryl-substituted (dihydro)pyrrolo[3,2,1-hi]indoles, a class of potent COX-2 inhibitors with tricyclic core structure

Laube, M.; Gassner, C.; Sharma, S. K.; Günther, R.; Pigorsch, A.; König, J.; Köckerling, M.; Wuest, F.; Pietzsch, J.; Kniess, T.

Involved research facilities

  • PET-Center

Effects of pulmonary acid aspiration on the regional pulmonary blood flow within the first hour after injury: an observational study in rats

Richter, T.; Bergmann, R.; Pietzsch, J.; Mueller, M. P.; Koch, T.

Involved research facilities

  • PET-Center

2014

Organotypical vascular model for characterization of radioprotective compounds: Studies on antioxidant 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitors

Ullm, S.; Laube, M.; Bechmann, N.; Knieß, T.; Pietzsch, J.

Involved research facilities

  • PET-Center

2,3-Diaryl-substituted indole based COX-2 inhibitors as leads for imaging tracer development

Laube, M.; Tondera, C.; Sharma, S. K.; Bechmann, N.; Pietzsch, F.-J.; Pigorsch, A.; Köckerling, M.; Wuest, F.; Pietzsch, J.; Kniess, T.

Involved research facilities

  • PET-Center

In Vivo Fluorescence Imaging and Urinary Monoamines as Surrogate Biomarkers of Disease Progression in a Mouse Model of Pheochromocytoma

Ullrich, M.; Bergmann, R.; Peitzsch, M.; Cartellieri, M.; Quin, N.; Erhart-Bornstein, M.; Block, N. L.; Schalley, A. V.; Pietzsch, J.; Eisenhofer, G.; Bornstein, S. R.; Ziegler, C. G.

Involved research facilities

  • PET-Center

Biocompatibility and inflammatory response in vitro and in vivo to gelatin-based biomaterials with tailorable elastic properties

Ullm, S.; Krüger, A.; Tondera, C.; Gebauer, T. P.; Neffe, A. T.; Lendlein, A.; Jung, F.; Pietzsch, J.

Involved research facilities

  • PET-Center

Assessment of the best N3− donors in preparation of [M(N)(PNP)]-based (M = 99mTc-; 188Re) target-specific radiopharmaceuticals: Comparison among succinic dihydrazide (SDH), N-methyl-S-methyl dithiocarbazate (HDTCZ) and PEGylated N-methyl-S-methyl dithiocarbazate (HO2C-PEG600-DTCZ)

Carta, D.; Jentschel, C.; Thieme, S.; Salvarese, N.; Morellato, N.; Refosco, F.; Ruzza, P.; Bergmann, R.; Pietzsch, H.-J.; Bolzati, C.

Involved research facilities

  • PET-Center

Bispidine dioxotetraaza macrocycles: a new class of bispidines for 64Cu PET imaging

Comba, P.; Kubeil, M.; Pietzsch, J.; Rudolf, H.; Stephan, H.; Zarschler, K.

Involved research facilities

  • PET-Center

Radiofluorination and first radiopharmacological characterization of a SWLAY peptide-based ligand targeting EphA2

Pretze, M.; Mosch, B.; Bergmann, R.; Steinbach, J.; Pietzsch, J.; Mamat, C.

Involved research facilities

  • PET-Center

Effect of [18F]FMISO stratified dose-escalation on local control in FaDu hSCC in nude mice

Schütze, C.; Bergmann, R.; Brüchner, K.; Mosch, B.; Yaromira, A.; Zips, D.; Hessel, F.; Krause, M.; Thames, H.; Kotzerke, J.; Steinbach, J.; Baumann, M.; Beuthien-Baumann, B.

Involved research facilities

  • PET-Center

Metastatic potential of B16-F10 melanoma cells is enhanced by extracellular S100A4 derived from RAW264.7 macrophages

Haase-Kohn, C.; Wolf, S.; Herwig, N.; Mosch, B.; Pietzsch, J.

Involved research facilities

  • PET-Center

Influence of different chelators on the radiochemical properties of a 68-Gallium labelled bombesin analogue.

Asti, M.; Iori, M.; Capponi, P. C.; Atti, G.; Rubagotti, S.; Martin, R.; Brennauer, A.; Müller, M.; Bergmann, R.; Erba, P. A.; Versari, A.

Involved research facilities

  • PET-Center

Radiolabeled anti-EGFR-antibody improves local tumor control after external beam radiotherapy and offers theragnostic potential

Koi, L.; Bergmann, R.; Brüchner, K.; Pietzsch, J.; Pietzsch, H.-J.; Krause, M.; Steinbach, J.; Zips, D.; Baumann, M.

Involved research facilities

  • PET-Center

Radiolabeled cetuximab conjugates for EGFR targeted cancer diagnostics and therapy

Sihver, W.; Pietzsch, J.; Krause, M.; Baumann, M.; Steinbach, J.; Pietzsch, H. J.

2013

Pulmonary Blood Flow Increases in Damaged Regions Directly after Acid Aspiration in Rats

Richter, T.; Bergmann, R.; Knels, L.; Hofheinz, F.; Kasper, M.; Deile, M.; Pietzsch, J.; Ragaller, M.; Koch, T.

Involved research facilities

  • PET-Center

Synthesis and radiopharmacological evaluation of 64Cu-labeled bombesin analogs featuring a bis(2-pyridylmethyl) 1,4,7-triazacyclononane chelator

Bergmann, R.; Ruffani, A.; Graham, B.; Spiccia, L.; Steinbach, J.; Pietzsch, J.; Stephan, H.

Involved research facilities

  • PET-Center

Tissue transglutaminase: an emerging target for therapy and imaging

Pietsch, M.; Wodtke, R.; Pietzsch, J.; Löser, R.

Involved research facilities

  • PET-Center

In vivo comparison of DOTA based 68Ga-labelled bisphosphonates for bone imaging in non-tumour models

Meckel, M.; Fellner, M.; Thieme, N.; Bergmann, R.; Kubicek, V.; Rösch, F.

Involved research facilities

  • PET-Center

Synthesis and radiopharmacological evaluation of a high-affinity and metabolically stabilized 18F-labeled bombesin analogue for molecular imaging of gastrin-releasing peptide receptor-expressing prostate cancer

Richter, S.; Wuest, M.; Krieger, S. S.; Rogers, B. E.; Friebe, M.; Bergmann, R.; Wuest, F.

Involved research facilities

  • PET-Center

Radiosynthesis and in vivo Evaluation of a 18F-Labelled Styryl-Benzoxazole Derivative for ß-Amyloid Targeting

Ribeiro Morais, G.; Kniess, T.; Bergmann, R.; Gano, L.; Abrunhosa, A.; Santos, I.; Paulo, A.

Involved research facilities

  • PET-Center

Optimization of Pentadentate Bispidines as Bifunctional Chelators for 64Cu Positron Emission Tomography (PET)

Comba, P.; Hunoldt, S.; Morgen, M.; Pietzsch, J.; Stephan, H.; Wadepohl, H.

Involved research facilities

  • PET-Center

An Efficient Bioorthogonal Strategy Using CuAAC Click Chemistry for Radiofluorinations of SNEW Peptides and the Role of Copper Depletion

Pretze, M.; Kuchar, M.; Bergmann, R.; Steinbach, J.; Pietzsch, J.; Mamat, C.

Involved research facilities

  • PET-Center

Synthesis and radiopharmacological characterisation of a fluorine-18 labelled azadipeptide nitrile as potential PET Tracer for in vivo imaging of cysteine cathepsins

Löser, R.; Bergmann, R.; Frizler, M.; Mosch, B.; Dombrowski, L.; Kuchar, M.; Steinbach, J.; Gütschow, M.; Pietzsch, J.

Involved research facilities

  • PET-Center

Recent trends in malignant melanoma biomarker research

Pietzsch, J.; Tandler, N.; Mosch, B.

Involved research facilities

  • PET-Center
  • Clinical Laboratory International 37(2013), 6-8

Anti-tumor effects of peptide analogues targeting neuropeptide hormone receptors on mouse pheochromocytoma cells

Ziegler, C. G.; Eisenhofer, G.; Schally, A. V.; Gebauer, L.; Gondek, K.; Ullrich, M.; Qin, N.; Bergmann, R.; Pietzsch, J.; Ehrhart-Bornstein, M.; Bornstein, S. R.

Involved research facilities

  • PET-Center

Radiolabeled COX-2 inhibitors for non-invasive visualization of COX-2 expression and activity - a critical update

Laube, M.; Kniess, T.; Pietzsch, J.

Involved research facilities

  • PET-Center

Ga-68- and Cu-64-Labeled NOTA-Albumin Conjugates for PET Sentinel Lymph Node Imaging

Schiller, E.; Bergmann, R.; Wunderlich, G.; Andreeff, M.; Jacob, A.; Pietzsch, H.-J.

Involved research facilities

  • PET-Center

Experimental hypoxia does not influence gene expression and protein synthesis of Eph receptors and ephrin ligands in human melanoma cells in vitro.

Reissenweber, B.; Mosch, B.; Pietzsch, J.

Involved research facilities

  • PET-Center

Investigations into the synthesis, radiofluorination and conjugation of a new [18F]fluorocyclobutyl prosthetic group and its in vitro stability using a tyrosine model system

Franck, D.; Kniess, T.; Steinbach, J.; Zitzmann-Kolbe, S.; Friebe, M.; Dinkelborg, L. M.; Graham, K.

Involved research facilities

  • PET-Center

Visualization of cyclooxygenase-2 using a 2,3-diarylsubstituted indole-based inhibitor and confocal laser induced cryofluorescence microscopy at 20 K in melanoma cells in vitro

Tondera, C.; Laube, M.; Wimmer, C.; Kniess, T.; Mosch, B.; Großmann, K.; Pietzsch, J.

Involved research facilities

  • PET-Center

Copper(II) chemistry of the functionalized macrocycle cyclam tetrapropionic acid

Comba, P.; Emmerling, F.; Jakob, M.; Kraus, W.; Kubeil, M.; Morgen, M.; Pietzsch, J.; Stephan, H.

2-Carbaborane-3-phenyl-1H-indoles—Synthesis via McMurry Reaction and Cyclooxygenase (COX) Inhibition Activity

Laube, M.; Neumann, W.; Scholz, M.; Lönnecke, P.; Crews, B.; Marnett, L. J.; Pietzsch, J.; Kniess, T.; Hey-Hawkins, E.

Involved research facilities

  • PET-Center

2012

Cerebral blood flow quantification in the rat: a direct comparison of arterial spin labeling MRI with radioactive microsphere PET

Bos, A.; Bergmann, R.; Strobel, K.; Hofheinz, F.; Steinbach, J.; van den Hoff, J.

Involved research facilities

  • PET-Center

Protein and non-protein biomarkers in melanoma: a critical update.

Tandler, N.; Mosch, B.; Pietzsch, J.

Involved research facilities

  • PET-Center

Synthesis, in silico, in vitro, and in vivo investigation of 5-[11C]methoxy-substituted sunitinib, a tyrosine kinase inhibitor of VEGFR-2

Caballero, J.; Muñoz, C.; Alzate-Morales, J. H.; Cunha, S.; Gano, L.; Bergmann, R.; Steinbach, J.; Kniess, T.

Involved research facilities

  • PET-Center

18F-Labeled phosphopeptide-cell-penetrating peptide dimers with enhanced cell uptake properties in human cancer cells

Richter, S.; Bouvet, V.; Wuest, M.; Bergmann, R.; Steinbach, J.; Pietzsch, J.; Neundorf, I.; Wuest, F.

Involved research facilities

  • PET-Center

Synthesis and cytotoxicity of pyridine and quinoline oxorhenium(V) complexes with tridentate (NS2, S-3)/monodentate (s) coordination

Segal, I.; Zablotskaya, A.; Kniess, T.; Shestakova, I.

Involved research facilities

  • PET-Center

18F-labelled CCR1-receptor antagonist is not suitable for imaging of Alzheimer's disease

Beuthien-Baumann, B.; Holthoff, V.; Mäding, P.; Bergmann, R.; Pawelke, B.; Holl, G.; von Kummer, R.; Kotzerke, J.; van den Hoff, J.

Involved research facilities

  • PET-Center

Fluorine-18-Radiolabeling and Radiopharmacological Characterization of a Benzodioxolylpyrimidine as a Radiotracer Targeting the Receptor Tyrosine Kinase EphB4

Mamat, C.; Mosch, B.; Neuber, C.; Köckerling, M.; Bergmann, R.; Pietzsch, J.

Involved research facilities

  • PET-Center

Novel 7α-alkoxy-17α-(4’-halophenylethynyl)estradiols as potential SPECT/PET imaging agents for estrogen receptor expressing tumors: synthesis and binding affinity evaluation

Neto, C.; Oliveira, M. C.; Gano Fernanda Marques, M. L.; Yasuda, T.; Thiemann, T.; Kniess, T.; Santos, I.

Involved research facilities

  • PET-Center

Design, Evaluation, and Comparison of Ghrelin Receptor Agonists and Inverse Agonists as Suitable Radiotracers for PET Imaging

Chollet, C.; Bergmann, R.; Pietzsch, J.; Beck-Sickinger, A. G.

Involved research facilities

  • PET-Center

Irradiation affects cellular properties and Eph receptor expression in human melanoma cells

Mosch, B.; Pietzsch, D.; Pietzsch, J.

Involved research facilities

  • PET-Center

Radioiodinated sunitinib as a potential radiotracer for imaging angiogenesis - radiosynthesis and first radiopharmacological evaluation of 5-[125I]Iodo-sunitinib

Kuchar, M.; Oliveira, M. C.; Gano, L.; Santos, I.; Knieß, T.

Involved research facilities

  • PET-Center

Radiohalogenated 4-anilinoquinazoline-based EGFR-TK inhibitors as potential cancer imaging agents

Neto, C.; Fernandes, C.; Oliveira, M. C.; Gano, L.; Mendes, F.; Kniess, T.; Santos, I.

Involved research facilities

  • PET-Center

Study of differences in the VEGFR2 inhibitory activities between semaxanib and SU5205 using 3D-QSAR, docking, and molecular dynamics simulations

Munoza, C.; Adasmea, F.; Alzate-Morales, J. H.; Vergara-Jaquea, A.; Kniess, T.; Caballero, J.

Involved research facilities

  • PET-Center

Radiolabeled small molecule inhibitors of VEGFR – recent advances

Kniess, T.

Involved research facilities

  • PET-Center

Specific targeting of hypoxic tumor tissue with nitroimidazole-peptide conjugates

Splith, K.; Bergmann, R.; Pietzsch, J.; Neundorf, I.

Involved research facilities

  • PET-Center

Site-selective radiolabeling of peptides by 18F-fluorobenzoylation with [18F]SFB in solution and on solid phase - a comparative study

Kuchar, M.; Pretze, M.; Knieß, T.; Steinbach, J.; Pietzsch, J.; Löser, R.

Involved research facilities

  • PET-Center

Radiosynthesis of a 18F-labeled 2,3-diarylsubstituted indole via McMurry coupling for functional characterization of cyclooxygenase-2 (COX-2) in vitro and in vivo

Kniess, T.; Laube, M.; Bergmann, R.; Graf, F.; Steinbach, J.; Wuest, F.; Pietzsch, J.

Involved research facilities

  • PET-Center

2011

Synthesis of an 18F-labeled cyclin-dependent kinase-2 inhibitor

Svensson, F.; Kniess, T.; Bergmann, R.; Pietzsch, J.; Wuest, F.

Involved research facilities

  • PET-Center

S100A2 in cancerogenesis: a friend or a foe?

Wolf, S.; Haase-Kohn, C.; Pietzsch, J.

Involved research facilities

  • PET-Center

S100 proteins in health and disease

Pietzsch, J.

Involved research facilities

  • PET-Center

Influence of storage on the position of the germinal disc in the fertilized unincubated chicken egg

Burkhardt, A.; Meister, S.; Bergmann, R.; Koch, E.

Involved research facilities

  • PET-Center

Copper-mediated cross-linking of S100A4, but not of S100A2, results in proinflammatory effects in melanoma cells

Haase-Kohn, C.; Wolf, S.; Lenk, J.; Pietzsch, J.

Involved research facilities

  • PET-Center

Phosphopeptides with improved cellular uptake properties as ligands for the polo-box domain of polo-like kinase 1

Richter, S.; Neundorf, I.; Loebner, K.; Gräber, M.; Berg, T.; Bergmann, R.; Steinbach, J.; Pietzsch, J.; Wuest, F.

Involved research facilities

  • PET-Center

Impact of functionalized coligands on the pharmacokinetics of 99mTc(III) ‘4+1’ mixed-ligand complexes conjugated to bombesin

Künstler, J.-U.; Bergmann, R.; Gniazdowska, E.; Kozminski, P.; Walther, M.; Pietzsch, H.-J.

Radiolabeling of phosphatidylserine-binding peptides with prosthetic groups N-[6-(4-[18F]fluorobenzylidene)aminooxyhexyl]maleimide ([18F]FBAM) and N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB)

Kapty, J.; Kniess, T.; Wuest, F.; Mercer, J. R.

Involved research facilities

  • PET-Center

Long-Acting Lipidated Analogue of Human Pancreatic Polypeptide Is Slowly Released into Circulation

Bellmann-Sickert, K.; Elling, C. E.; Madsen, A. N.; Little, P. B.; Lundgren, K.; Gerlach, L.-O.; Bergmann, R.; Holst, B.; Schwartz, T. W.; Beck-Sickinger, A. G.

Involved research facilities

  • PET-Center

Synthesis, characterization and biological evaluation of [188Re(N)(cys∼)(PNP)]+/0 mixed-ligand complexes as prototypes for the development of 188Re(N)-based target-specific radiopharmaceuticals

Thieme, S.; Agostini, S.; Bergmann, R.; Pietzsch, J.; Pietzsch, H.-J.; Carta, D.; Salvarese, N.; Refosco, F.; Bolzati, C.

Involved research facilities

  • PET-Center

Synthesis and evaluation of 1,5-diaryl-substituted tetrazoles as novel selective cyclooxygenase-2 (COX-2) inhibitors

Al-Hourani, B. J.; Sharma, S. K.; Mane, J. Y.; Tuszynski, J.; Baracos, V.; Kniess, T.; Suresh, M.; Pietzsch, J.; Wuest, F.

Involved research facilities

  • PET-Center

Expression, purification and fluorine-18 radiolabeling of recombinant S100A4: a potential probe for molecular imaging of receptor for advanced glycation endproducts in vivo?

Wolf, S.; Haase-Kohn, C.; Lenk, J.; Hoppmann, S.; Bergmann, R.; Steinbach, J.; Pietzsch, J.

Involved research facilities

  • PET-Center
  • Amino Acids 41(2011), 809-820

A Novel Tetrabranched Neurotensin(8-13) Cyclam Derivative: Synthesis, 64Cu-Labeling and Biological Evaluation

Röhrich, A.; Bergmann, R.; Kretzschmann, A.; Noll, S.; Steinbach, J.; Pietzsch, J.; Stephan, H.

Involved research facilities

  • PET-Center

Synthesis and biological evaluation of new [Tc(N)(PS)]-based mixed-ligand compounds useful in design of target-specific radiopharmaceuticas: the 2-methoxyphenylpiperazine dithiocarbamate derivatives as example

Bolzati, C.; Salvarese, N.; Carta, D.; Refosco, F.; Dolmella, A.; Pietzsch, H.-J.; Bergmann, R.; Bandoli, G.

Involved research facilities

  • PET-Center

Automated radiosynthesis of the thiol-reactive labeling agent N-[6-(4-[18F]fluorobenzylidene)aminooxyhexyl]maleimide ([18F]FBAM)

Knieß, T.; Kuchar, M.; Pietzsch, J.

Involved research facilities

  • PET-Center

2010

Modulation of Adrenal Aldosterone Release by Oxidative Modification of Low-Density Lipoprotein

Ansurudeen, I.; Pietzsch, J.; Graessler, J.; Ehrhart-Bornstein, M.; Saha, S.; Bornstein, S. R.; Kopprasch, S.

Involved research facilities

  • PET-Center

Identification of transport processes in bioirrigated muddy sediments by [18F]fluoride PET (Positron Emission Tomography)

Roskosch, A.; Lewandowski, J.; Bergmann, R.; Wilke, F.; Brenner, W.; Burchert, R.

Involved research facilities

  • PET-Center

Comparison of the stability of Y-90-, Lu-177- and Ga-68- labeled human serum albumin microspheres (DOTA-HSAM)

Wunderlich, G.; Schiller, E.; Bergmann, R.; Pietzsch, H.-J.

Involved research facilities

  • PET-Center

Preparation, 99mTc-labeling and biodistribution studies of a PNA oligomer containing a new ligand derivative of 2,2′-dipicolylamine

Gasser, G.; Jäger, K.; Zenker, M.; Bergmann, R.; Steinbach, J.; Stephan, H.; Metzler-Nolte, N.

Involved research facilities

  • PET-Center

Novel 99mTc '4 + 1' peptide conjugates: Tuning the biodistribution by variation of coligands

Künstler, J.-U.; Seidel, G.; Bergmann, R.; Gniazdowska, E.; Walther, M.; Schiller, E.; Decristoforo, C.; Stephan, H.; Haubner, R.; Steinbach, J.; Pietzsch, H.-J.

Involved research facilities

  • PET-Center

Eph Receptors and Ephrin Ligands: Important Players in Angiogenesis and Tumor Angiogenesis

Mosch, B.; Reissenweber, B.; Neuber, C.; Pietzsch, J.

Involved research facilities

  • PET-Center

Cyclin-Dependent Kinase 4/6 (Cdk4/6) Inhibitors: Perspectives in Cancer Therapy and Imaging

Graf, F.; Mosch, B.; Koehler, L.; Bergmann, R.; Wuest, F.; Pietzsch, J.

Involved research facilities

  • PET-Center
  • Mini-Reviews in Medicinal Chemistry 10(2010), 527-539
    ISSN: 1389-5575

Synthesis of neurotensin(8-13)-phosphopeptide heterodimers via click chemistry

Richter, S.; Ramenda, T.; Bergmann, R.; Knieß, T.; Steinbach, J.; Pietzsch, J.; Wuest, F.

Radiosynthesis and radiopharmacological evaluation of cyclin-dependent kinase 4 (Cdk4) inhibitors

Koehler, L.; Graf, F.; Bergmann, R.; Steinbach, J.; Pietzsch, J.; Wuest, F.

Scavenger receptors are associated with cellular interactions of S100A12 in vitro and in vivo

Hoppmann, S.; Steinbach, J.; Pietzsch, J.

Effects of posture on regional pulmonary blood flow in rats as measured by PET

Richter, T.; Bergmann, R.; Pietzsch, J.; Közle, I.; Hofheinz, F.; Schiller, E.; Ragaller, M.; van den Hoff, J.

Improved Multimodality Imaging Using Alginate Molding in Xenograft Tumor Models

Strobel, K.; Bergmann, R.; Meister, S.; van den Hoff, J.; Pietzsch, J.

2009

Fluorine-18 labeling of phosphopeptides: a potential approach for the evaluation of phosphopeptide metabolism in vivo.

Richter, S.; Bergmann, R.; Pietzsch, J.; Ramenda, T.; Steinbach, J.; Wuest, F.

Analysis of non-protein amino acids as specific markers of protein oxidation: the use of N(O,S)-ethoxycarbonyl ethyl ester and N(O,S)-ethoxycarbonyl trifluoroethyl ester derivatives and GC-MS

Pietzsch, J.; Pietzsch, F.-J.; Kopprasch, S.

  • Trends in Chromatography 5(2009), 15-20

Radiolabelling of proteins with fluorine-18 via click chemistry

Ramenda, T.; Knieß, T.; Bergmann, R.; Steinbach, J.; Wüst, F.

Influence of irradiation on metabolism and metastatic potential of B16-F10 melanoma cells

Mosch, B.; Müller, K.; Steinbach, J.; Pietzsch, J.

PET-Tracer für die onkologische Diagnostik: Welche radiomarkierten Substanzen sind relevant?

Knieß, T.; Steinbach, J.

  • Onkologische Pharmazie 11(2009)4, 4-5
    ISSN: 1437-8825

Autoradiographic studies of rhenium-188-hydroxyethylidine diphosphonate in normal skeleton and osteoblastic bone metastases in a rat model of metastatic prostate cancer

Liepe, K.; Geidel, H. H.; Bergmann, R.; Haase, M.; Runge, R.; Kotzerke, J.

Comparison of [18F]FDG uptake and distribution with hypoxia and proliferation in FaDu human squamous cell carcinoma (hSCC) xenografts after single dose irradiation

Bruechner, K.; Bergmann, R.; Santiago, A.; Mosch, B.; Yaromina, A.; Hessel, F.; Hofheinz, F.; van den Hoff, J.; Baumann, M.; Beuthien-Baumann, B.

Reduction of Arteriosclerotic Nanoplaque Formation and Size by n-3 Fatty Acids in Patients after Valvular Defect Operation

Koppe, C.; Rodriguez, M.; Winkler, K.; Pietzsch, J.; Neumann, K.; Hiemann, N. H.; Hetzer, R.; Malmsten, M.; Siegel, G.

Direct labelling of peptides with 2-[F-18]fluoro-2-deoxy-D-glucose ([F-18]FDG)

Wuest, F.; Hultsch, C.; Berndt, M.; Bergmann, R.

Radiosynthesis of New [90Y]-DOTA-Based Maleimide Reagents Suitable for the Prelabeling of Thiol-Bearing L-Oligonucleotides and Peptides

Schlesinger, J.; Fischer, C.; Közle, I.; Vonhoff, S.; Klussmann, S.; Bergmann, R.; Pietzsch, H.-J.; Steinbach, J.

Fluorine-18 radiolabeling of native and oxidized proteins: An important tool in the pathophysiologists’ toolbox

Pietzsch, J.; Wuest, F.

  • Chimica Oggi - Chemistry Today 27(2009), 12-14

Synthesis and radiopharmacological investigation of 3-[4’-[18F]fluorobenzylidenyl]-indolin-2-one as possible tyrosine kinase inhibitor

Knieß, T.; Bergmann, R.; Kuchar, M.; Steinbach, J.; Wüst, F.

Fluorine-18-radiolabeled S100A12: a potential probe for functional characterization of inflammatory processes in vivo

Hoppmann, S.; Richter, S.; Steinbach, J.; Pietzsch, J.

  • Poster
    9th World Congress on Inflammation, 06.-10.07.2009, Tokyo, Japan
  • Inflammation Research 58(2009)Suppl. 2, S145-S146
    ISSN: 1023-3830

Hexadentate Bispidine Derivatives as Versatile Bifunctional Chelate Agents for Copper(II) Radioisotopes

Juran, S.; Walther, M.; Stephan, H.; Bergmann, R.; Steinbach, J.; Kraus, W.; Emmerling, F.; Comba, P.

Synthesis and cyclooxygenase inhibition of various (aryl-1,2,3-triazole-1-yl)-methanesulfonylphenyl derivatives

Wuest, F.; Tang, X.; Knieß, T.; Pietzsch, J.; Suresh, M.

Radiosynthesis and radiopharmacological evaluation of [N-methyl-11C]Org 34850 as a glucocorticoid receptor (GR)-binding radiotracer

Wüst, F.; Knieß, T.; Henry, B.; Peeters, B. W. M. M.; Wiegerinck, P. H. G.; Pietzsch, J.; Bergmann, R.

Prediabetic and diabetic in vivo modification of circulating low density lipoprotein attenuates its stimulatory effect on adrenal mineralocorticoid secretion

Kopprasch, S.; Pietzsch, J.; Ansurudeen, I.; Graessler, J.; Krug, A. W.; Erhart-Bornstein, M.; Bornstein, S. R.

Validation of 99mTc-labeled "4+1" fatty acids for myocardial metabolism and flow imaging Part 2: Subcellular distribution

Mirtschink, P.; Stehr, S. N.; Walther, M.; Pietzsch, J.; Bergmann, R.; Pietzsch, H.-J.; Weichsel, J.; Pexa, A.; Dieterich, P.; Wunderlich, G.; Binas, B.; Kropp, J.; Deussen, A.

Validation of 99mTc-labeled "4+1" fatty acids for myocardial metabolism and flow imaging Part 1: Myocardial extraction and biodistribution

Mirtschink, P.; Stehr, S. N.; Walther, M.; Pietzsch, J.; Bergmann, R.; Pietzsch, H.-J.; Weichsel, J.; Pexa, A.; Dieterich, P.; Wunderlich, G.; Binas, B.; Kropp, J.; Deussen, A.

Cell cycle regulating kinase Cdk4 as a potential target for tumor cell treatment and tumor imaging

Graf, F.; Köhler, L.; Knieß, T.; Wüst, F.; Mosch, B.; Pietzsch, J.

Human S100A12: a novel key player in inflammation?

Pietzsch, J.; Hoppmann, S.

Systematic comparison of two novel thiol-reactive prosthetic groups for 18F labeling of peptides and proteins with the acylation agent succinimidyl-4-[18F]fluorobenzoate [18F]SFB

Wüst, F.; Köhler, L.; Berndt, M.; Pietzsch, J.

  • Amino Acids 36(2009), 283-295
    ISSN: 0939-4451

2008

Detailed Analysis Concerning the Biodistribution and Metabolism of Human Calcitonin-Derived Cell-Penetrating Peptides

Neundorf, I.; Rennert, R.; Franke, J.; Közle, I.; Bergmann, R.

Effects of pioglitazone and/or simvastatin on low density lipoprotein subfractions in non-diabetic patients with high cardiovascular risk: A sub-analysis from the PIOSTAT study

Leonhardt, W.; Pfützner, A.; Müller, J.; Pietzsch, J.; Forst, T.; Karagiannis, E.; Lübben, G.; Hanefeld, M.

Synthesis and evaluation in vitro and in vivo of a 11C-labeled cyclooxygenase-2 (COX-2) inhibitor

Wüst, F.; Knieß, T.; Bergmann, R.; Pietzsch, J.

Factfile: S100A12

Pietzsch, J.

  • Open Access Logo Calcium Binding Proteins 3(2008), 18-21

Yttrium-86-labelled human serum albumin microspheres: relation of surface structure with in vivo stability

Schiller, E.; Bergmann, R.; Pietzsch, J.; Noll, B.; Sterger, A.; Johannsen, B.; Wunderlich, G.; Pietzsch, H.-J.

Synthesis and Application of [18F]FDG-maleimidehexyloxime ([18F]FDG-MHO): A [18F]FDG-based Prosthetic Group for the Chemoselective 18F-Labeling of Peptides and Proteins

Wüst, F.; Berndt, M.; Bergmann, R.; van den Hoff, J.; Pietzsch, J.

  • Bioconjugate Chemistry 19(2008)6, 1202-1210

An 86Y-Labeled Mirror-Image Oligonucleotide: Influence of Y-DOTA Isomers on the Biodistribution in Rats

Schlesinger, J.; Közle, I.; Bergmann, R.; Tamburini, S.; Bolzati, C.; Tisato, F.; Noll, B.; Klussmann, S.; Vonhoff, S.; Wüst, F.; Pietzsch, H.-J.; Steinbach, J.

  • Bioconjugate Chemistry 19(2008), 928-939
    DOI: 10.1021/bc700453h
    Cited 31 times in Scopus
  • Lecture (Conference)
    Turku PET Symposium New Targets in Molecular Imaging, 24.-27.05.2008, Turku, Finland
  • Contribution to proceedings
    Turku PET Symposium New Targets in Molecular Imaging, 24.-27.05.2008, Turku, Finland
    Abstracts of the XI Turku PET Symposium, Kaarina, Finland: Painola, 978-951-29-3563-5, 11

Facile synthesis of various nitro-substituted derivatives of semaxinib (SU 5416)

Knieß, T.; Kuchar, M.; Wüst, F.

Radiolabeled glucocorticoids as molecular probes for imaging brain glucocorticoid receptors by means of positron-emission-tomography (PET)

Steiniger, B.; Knieß, T.; Bergmann, R.; Pietzsch, J.; Wüst, F.

  • Mini-Reviews in Medicinal Chemistry 8(2008)7, 728-739
    ISSN: 1389-5575

Radiosynthesis of n.c.a. sodium [18F]fluoroacetate and radiopharmacological characterization in rats and tumour-xenografted mice

Richter, S.; Bergmann, R.; Pietzsch, J.; Beuthien-Baumann, B.; Wüst, F.

  • Current Radiopharmaceuticals 1(2008)2, 103-109
    ISSN: 1874-4710

Synthesis, Copper(II) Complexation, 64Cu-Labeling and Bioconjugation of a New Bis(2-pyridylmethyl) Derivative of 1,4,7-Triazacyclononane

Gasser, G.; Tjioe, L.; Graham, B.; Belousoff, M. J.; Juran, S.; Walther, M.; Künstler, J.-U.; Bergmann, R.; Stephan, H.; Spiccia, L.

  • Bioconjugate Chemistry 19(2008)3, 719-730

Expression, purification and fluorine-18 radiolabeling of recombinant S100 proteins - potential probes for molecular imaging of receptor for advanced glycation endproducts (RAGE) in vivo

Hoppmann, S.; Haase, C.; Richter, S.; Pietzsch, J.

Glycoxidation of low-density lipoprotein in impaired glucose tolerance: implications for the pathogenesis of diabetic vascular disease

Kopprasch, S.; Graessler, J.; Bornstein, S. R.; Pietzsch, J.

  • Vascular Disease Prevention 5(2008), 24-28
    ISSN: 1567-2700

Localized proton magnetic resonance spectroscopy of lipids in adipose tissue at high spatial resolution in mice in vivo

Strobel, K.; van den Hoff, J.; Pietzsch, J.

Modified “4+1” Mixed Ligand Technetium Labeled Fatty Acids for Myocardial Imaging: Evaluation of Myocardial Uptake and Biodistribution

Mirtschink, P.; Stehr, S. N.; Pietzsch, H.-J.; Bergmann, R.; Pietzsch, J.; Wunderlich, G.; Heintz, A. C.; Kropp, J.; Spies, H.; Kraus, W.; Deussen, A.; Walther, M.

Practical experiences with the synthesis of [11C]CH3 trough gas phase iodination reaction using a TRACERlabFXC synthesis module

Knieß, T.; Rode, K.; Wüst, F.

2007

Experimental Evaluation of Functional Imaging for Radiotherapy

Zips, D.; Yaromina, A.; Schütze, C.; Wüllrich, K.; Krause, M.; Krause, M.; Hessel, F.; Eicheler, W.; Dörfler, A.; Brüchner, K.; Menegakis, A.; Zhou, X.; Bergmann, R.; van den Hoff, J.; Beuthien-Baumann, B.; Baumann, M.

Factors influencing the formation of small dense low-density lipoprotein particles in dependence on the presence of the metabolic syndrome and on the degree of glucose intolerance

Julius, U.; Dittrich, M.; Pietzsch, J.

Myocardial uptake and biodistribution of newly designed technetium-labelled fatty acid analogues

Heintz, A. C.; Jung, C. M.; Stehr, S. N.; Mirtschink, P.; Walther, M.; Pietzsch, J.; Bergmann, R.; Pietzsch, H.-J.; Spies, H.; Wunderlich, G.; Kropp, J.; Deussen, A.

  • Nuclear Medicine Communications 28(2007)8, 637-647
    ISSN: 0143-3636

Experimental hypoxia is a potent stimulus for radiotracer uptake in vitro: Comparison of different tumor cells and primary endothelial cells

Oswald, J.; Treite, F.; Haase, C.; Kampfrath, T.; Mäding, P.; Schwenzer, B.; Bergmann, R.; Pietzsch, J.

Effect of increase of radiation dose on local control relates to pre-treatment FDG uptake in FaDu tumours in nude mice

Schütze, C.; Bergmann, R.; Yaromina, A.; Hessel, F.; Kotzerke, J.; Steinbach, J.; Baumann, M.; Beuthien-Baumann, B.

[18F]FBAM and [18F]FBOM: Novel Thiol-reactive prosthetic groups derived from 4-[18F]fluorobenzaldehyde

Vogler, L.; Berndt, M.; Pietzsch, J.; Wüst, F.

  • Lecture (Conference)
    14th Workshop der International Isotope Society, 21.-22.06.2007, Bad Soden, Germany
  • Journal of Labelled Compounds and Radiopharmaceuticals 50(2007), 1276-1286

L-Type Amino Acid Transporters LAT1 and LAT4 in Cancer: Uptake of 3-O- Methyl-6-18F-Fluoro-L-Dopa (18F-OMFD) in Human Adenocarcinoma and Squamous Cell Carcinoma in vitro and in vivo

Haase, C.; Bergmann, R.; Füchtner, F.; Hoepping, A.; Pietzsch, J.

Glycoxidised LDL isolated from subjects with impaired glucose tolerance increases CD36 and peroxisome proliferator-activator receptor gamma gene expression in macrophages

Graessler, J.; Pietzsch, J.; Westendorf, T.; Julius, U.; Bornstein, S. R.; Kopprasch, S.

Very stable 188Re-S4 chelates for labelling biomolecules, prepared with highly concentrated perrhenate eluates

Seifert, S.; Jentschel, C.; Bergmann, R.; Pietzsch, H.-J.; Wunderlich, G.; Kotzerke, J.; Steinbach, J.

  • Nuklearmedizin 5(2007), 181-184
    ISSN: 0029-5566

Lipid transfer protein activities in subjects with impaired glucose tolerance

Julius, U.; Jauhiainen, M.; Ehnholm, C.; Pietzsch, J.

  • Clinical Chemistry and Laboratory Medicine 45(2007)2, 237-243
    ISSN: 1434-6621

Synthesis of 18F-labeled neurotensin(8-13) via copper-mediated 1,3-dipolar [3+2]cycloaddition reaction

Ramenda, T.; Bergmann, R.; Wüst, F.

  • Letters in Drug Design & Discovery 4(2007)4, 279-285
    ISSN: 1570-1808

Labeling of low-density lipoproteins using the 18F-labeled thiol-reactive reagent N-[6-(4-[18F]fluorobenzylidene)aminooxyhexyl]maleimide [18F]FBAM

Berndt, M.; Pietzsch, J.; Wüst, F.

Radiolabelling of multimeric neurotensin(8-13) analogues with the short-lived positron emitter fluorine-18

Hultsch, C.; Berndt, M.; Bergmann, R.; Wüst, F.

Synthesis of 18F-labelled stilbenes from 4-[18F]fluorobenzaldehyde using the Horner-Wadsworth-Emmons reaction

Gester, S.; Pietzsch, J.; Wüst, F.

Synthesis and radiopharmacological characterization of [11C]AL-438 as a nonsteroidal ligand for imaging brain glucocorticoid receptors

Wüst, F.; Knieß, T.; Bergmann, R.; Henry, B.; Pietzsch, J.

  • Bioorganic & Medicinal Chemistry Letters 17(2007), 4035-4039

Synthesis and radiopharmacological characterization of 2β-carbo-2’-[18F]fluoroethoxy-3β-(4-bromo-phenyl)tropane ([18F]MCL-322) as a potential PET radiotracer for imaging the dopamine transporter (DAT)

Wüst, F.; Berndt, M.; Strobel, K.; van den Hoff, J.; Peng, X.; Neumeyer, J. L.; Bergmann, R.

Synthesis and biological evaluation of a new type of 99mTechnetium-labeled fatty acid for myocardial metabolism imaging

Walther, M.; Jung, C.; Bergmann, R.; Pietzsch, J.; Rode, K.; Fahmy, K.; Mirtschink, P.; Stehr, S.; Heintz, A.; Wunderlich, G.; Kraus, W.; Pietzsch, H.-J.; Kropp, J.; Deussen, A.; Spies, H.

  • Bioconjugate Chemistry 18(2007), 216-230
    ISSN: 10.1021/bc0601222

2006

Neurotensin Receptors in Adeno- and Squamous Cell Carcinoma

Haase, C.; Bergmann, R.; Oswald, J.; Zips, D.; Pietzsch, J.

  • Open Access Logo Anticancer Research 26(2006), 3527-3534

Biodistribution and catabolism of 18F-labeled N-epsilon-fructoselysine as a model of Amadori products

Hultsch, C.; Hellwig, M.; Pawelke, B.; Bergmann, R.; Rode, K.; Pietzsch, J.; Krause, R.; Henle, T.

Fluorescein-labeled stable neurotensin derivatives

Maes, V.; Hultsch, C.; Kohl, S.; Bergmann, R.; Hanke, T.; Tourwé, D.

  • Journal of Peptide Science 12(2006), 505-508

Synthesis and evaluation of novel multimeric neurotensin(8-13) analogs

Hultsch, C.; Pawelke, B.; Bergmann, R.; Wüst, F.

  • Bioorganic & Medicinal Chemistry 14(2006)17, 5913-5920

Preparation and Biological Characterization of Isomeric 188Re(V) Oxocomplexes with Tetradentate S4 Ligands Derived from DMSA for Labeling of Biomolecules

Seifert, S.; Heinrich, T.; Jentschel, C.; Smuda, C.; Bergmann, R.; Pietzsch, H.-J.

Chitosan-encapsulated Keggin anion [Ti2W10PO40]7-: Synthesis, characterization and cellular uptake studies

Meißner, T.; Bergmann, R.; Oswald, J.; Rode, K.; Richter, W.; Zänker, H.; Kraus, W.; Emmerling, F.; Reck, G.; Stephan, H.

Synthesis and Radiopharmacological Characterisation of 86Y- and 68Ga-Labelled L-RNA Oligonucleotides as Molecular Probes for Positron Emission Tomography (PET)

Schlesinger, J.; Bergmann, R.; Klussmann, S.; Wüst, F.

  • Letters in Drug Design & Discovery 3(2006)5, 330-335

[11C]SMe-ADAM, an imaging agent for the brain serotonin transporter: Synthesis, pharmacological characterization and microPET studies in rats

Zessin, J.; Deuther-Conrad, W.; Kretzschmar, M.; Wüst, F.; Pawelke, B.; Brust, P.; Steinbach, J.; Bergmann, R.

  • Nuclear Medicine and Biology 33(2006)1, 53-63

2005

Positron emission tomography in food sciences

Pietzsch, J.; van den Hoff, J.

Small animal positron emission tomography in food sciences

Bergmann, R.; Pietzsch, J.

Biodistribution and catabolism of 18F-labelled isopeptide N (varepsilon)-(gamma-glutamyl)-L-lysine

Hultsch, C.; Bergmann, R.; Pawelke, B.; Pietzsch, J.; Wüst, F.; Johannsen, B.; Henle, T.

Catabolism of native and oxidized low density lipoproteins (LDL): in vivo insights from small animal positron emission tomography studies

Pietzsch, J.; Bergmann, R.; Wüst, F.; Pawelke, B.; Hultsch, C.; van den Hoff, J.

Glucose-Induced Enhancement of Hemin-Catalyzed LDL Oxidation In Vitro and In Vivo

Julius, U.; Pietzsch, J.

  • Antioxidants and Redox Signaling 7(2005)11-12, 1507-1512

Pathological consequenses of systemic oxidative stress and dyslipidemia in impaired glucose tolerance and diabetes mellitus

Kopprasch, S.; Grässler, J.; Pietzsch, J.

  • Trends in Cell & Molecular Biology 1(2005), 1-14

In vivo metabolism of oxidized low density lipoproteins: Insights from small animal positron emission tomography (PET) studies

Pietzsch, J.; Bergmann, R.; Wüst, F.; van den Hoff, J.

  • Recent Research Developments in Molecular & Cellular Biochemistry 2(2005), 153-177

Synthesis and biodistribution of an 18F-labelled resveratrol derivative for small animal positron emission tomography (PET)

Gester, S.; Wüst, F.; Pawelke, B.; Bergmann, R.; Pietzsch, J.

Dramatic effect of the tridentate ligand on the stability of Tc-99m "3+1" oxo complexes bearing arylpiperazine derivatives

Fernandes, C.; Correia, D. G.; Gano, L.; Santos, I.; Seifert, S.; Syhre, R.; Bergmann, R.; Spies, H.

  • Bioconjugate Chemistry 16(2005)3, 660-668
    ISSN: 1043-1802

Synthesis and radiopharmacological evaluation of 2´-(4-fluorophenyl)-21-[18F]fluoro-20-oxo-11β,17α-dihydroxy-pregn-4-eno[3,2-c]pyrazole as potential glucocorticoid receptor ligand for positron emission tomography (PET)

Wüst, F.; Knieß, T.; Kretzschmar, M.; Bergmann, R.

  • Bioorganic & Medicinal Chemistry Letters 15(2005), 1303-1306

Synthesis and biological evaluation of S-[11C]methylated mercaptoimidazolde piperazinyl derivatives as potential radioligands for imaging 5-HT1A receptors by positron emission tomography (PET)

Garcia, R.; Xavier, C.; Paulo, A.; Santos, I.; Knieß, T.; Bergmann, R.; Wüst, F.

  • Journal of Labelled Compounds and Radiopharmaceuticals 48(2005), 301-315

N-Arylation of indoles with 4-[18F]fluoroiodobenzene: synthesis of 18F-labelled σ2 receptor ligands for positron emission tomography (PET)

Wüst, F.; Knieß, T.

2004

Fluorine-18 radiolabeling of low-density lipoproteins: a potential approach for characterization and differentiation of metabolism of native and oxidized low-density lipoproteins in vivo.

Pietzsch, J.; Bergmann, R.; Rode, K.; Hultsch, C.; Pawelke, B.; Wüst, F.; van den Hoff, J.

  • Nuclear Medicine and Biology 31(2004), 1043-1050

3-O-Methyl-6-18F-Fluoro-L-Dopa, a New Tumor Imaging Agent: Investigation of Transport Mechanism In Vitro

Bergmann, R.; Pietzsch, J.; Füchtner, F.; Pawelke, B.; Beuthien-Baumann, B.; Johannsen, B.; Kotzerke, J.

  • Journal of Nuclear Medicine 45(2004), 2116-2122

Synthesis and biological evaluation of silylated mixed-ligand 99mTc complexes with the [PNS/S] donor atom set

Fernandes, C.; Knieß, T.; Gano, L.; Seifert, S.; Spies, H.; Santos, I.

Cyclopentadienyl tricarbonyl complexes of 99mTC for the in vivo imaging of the serotonin 5-HT1A receptor in the brain

Saidi, M.; Kretzschmar, M.; Seifert, S.; Bergmann, R.; Pietzsch, H.-J.

Synthesis of 4-([18F]fluoromethyl)-2-chlorophenylisothiocyanate: A novel bifunctional 18F-labelling agent

Wüst, F.; Müller, M.; Bergmann, R.

  • Radiochimica Acta 92(2004)4-6, 349-353

No-carrier added synthesis of 18F-labelled nucleosides using Stille cross-coupling reactions with 4-[18F]fluoroiodobenzene

Wüst, F.; Knieß, T.

The effect of garlic on arteriosclerotic nanoplaque formation and size

Siegel, G.; Malmsten, M.; Pietzsch, J.; Schmidt, A.; Buddecke, E.; Michel, F.; Ploch, M.; Schneider, W.

  • Phytomedicine 11(2004), 24-35

Novel Procedures for Preparing 99mTc(III) Complexes with Tetradentate/Monodentate Coordination of Varying Lipophilicity and Adaptation to 188Re Analogues

Seifert, S.; Künstler, J.-U.; Pietzsch, H.-J.; Pawelke, B.; Bergmann, R.; Spies, H.

Oxidativ modifizierte Lipoproteine und deren Antikörper bei Patienten mit Antiphospholipid-Syndrom

Roch, B.; Kopprasch, S.; Pietzsch, J.; Schröder, H.

The pivotal role of scavenger receptor CD36 and phagocyte-derived oxidants in oxidized low density lipoprotein-induced adhesion to endothelial cells

Kopprasch, S.; Pietzsch, J.; Westendorf, T.; Kruse, H.-J.; Graessler, J.

  • International Journal of Biochemistry and Cell Biology 36(2004)3, 460-471

The protective effects of HDL and its constituents against neutrophil respiratory bust activation by hypochlirite-oxidized LDL

Kopprasch, S.; Pietzsch, J.; Graessler, J.

  • Molecular and Cellular Biochemistry 258(2004), 121-127

Analysis of non-protein amino acids as specific markers of low density lipoprotein apolipoprotein B-100 oxidation in human atherosclerotic lesions: the use of N(O,S)-ethoxycarbonyl trifluoroethyl ester derivatives and GC-MS

Pietzsch, J.; Bergmann, R.; Kopprasch, S.

  • Spectroscopy 18(2004),177-183

Analysis of 6-hydroxy-2-aminocaproic acid (HACA) as a specific marker of protein oxidation: The use of N(O,S)-ethoxycarbonyl trifluoroethyl ester derivatives and gas chromatography/mass spectrometry

Pietzsch, J.; Bergmann, R.

  • Amino Acids 26(2004), 45-51

2003

3-O-Methyl-6-[18F]Fluoro-L-DOPA and its Evaluation in Brain Tumour Imaging

Beuthien-Baumann, B.; Bredow, J.; Burchert, W.; Füchtner, F.; Bergmann, R.; Alheit, H.-D.; Reiss, G.; Hliscs, R.; Steinmeier, R.; Franke, W.-G.; Johannsen, B.; Kotzerke, J.

  • European Journal of Nuclear Medicine and Molecular Imaging (2003) 30: 1004-1008

In vivo Measurement of the Serotonin Transporter with (S)-([18F]fluoromenthyl)-(+)-McN5652

Brust, P.; Hinz, R.; Kuwabara, H.; Hesse, S.; Zessin, J.; Pawelke, B.; Stephan, H.; Bergmann, R.; Steinbach, J.; Sabri, O.

  • Neuropsychopharmacology (2003) 28, 2010-2019

Validation of different chemilumigenic substrates for detecting extracellular generation of reactive oxygen species by phagocytes and endothelial cells

Kopprasch, S.; Pietzsch, J.; Graessler, J.

  • Luminescence (2003) 18: 268-273

Fortschritte in der Aminosäureanalytik: N(O,S)-Ethoxycarbonyl-(trifluoro)ethylester-Derivate

Pietzsch, J.

  • Bioforum 10/2003, 643-645

Measurement of 5-hydroxy-2-aminovaleric acid as a specific marker of iron-mediated oxidation of proline and arginine residues of low density lipoprotein aplipoprotein B-100 in human atherosclerotic lesions

Pietzsch, J.; Bergmann, R.

  • J Clin Pathol (2003) 56: 622-623

Flavonoide: Wirkmechanismen und neue Anwendungsmöglichkeiten (Teil 2)

Pietzsch, J.; Bergmann, R.; Wüst, F.

  • Bioforum (2003) 6:384-385

Flavonoide: Wirkmechanismen und neue Anwendungsmöglichkeiten (Teil 1)

Pietzsch, J.; Bergmann, R.; Wüst, F.

  • Bioforum (2003) 5: 289-291

Synthesis and Enzymatic Evaluation of Nucleosides Derived from 5-Iodo-2'-deoxyuridines

Knieß, T.; Grote, M.; Noll, B.; Johannsen, B.

  • Z. Naturforsch. 58b, 226-230 (2003)

Silylated mixed-ligand rhenium complexes with the [PNS/S] donor atom set

Knieß, T.; Fernandes, C.; Santos, I.; Kraus, W.; Spies, H.

  • Inorganica Chimica Acta 348 (2003) 237-241

Radiolabelling of isopeptide NEpsilon-(Gamma-glutamyl)-L-lysine by conjugation with N-succinimidyl-4-[18F]fluorobenzoate

Wüst, F.; Hultsch, C.; Bergmann, R.; Johannsen, B.; Henle, T.

  • Applied Radiation and Isotopes 59 (2003) 43-48

Increased cholesteryl ester transfer protein (CETP) activity in impaired glucose tolerance: relationship to high density lipoprotein metabolism

Pietzsch, J.; Fücker, K.

  • Croatian Medical Journal 44 (2): 171-177, 2003

Lack of association between serum paraoxonase (PON1) activities and increased oxidized LDL levels in impaired glucose tolerance and newly diagnosed diabetes mellitus

Kopprasch, S.; Pietzsch, J.; Kuhlisch, E.; Gräßler, J.

  • Journal of Clinical Endocrinology & Metabolism 2003; 88: 1711-1716

Analysis of 3-chlorotyrosine as a specific marker of protein oxidation: The use of N(O,S)-ethoxycarbonyl trifluoroethyl ester derivatives and gas chromatography/mass spectrometry

Pietzsch, J.; Kopprasch, S.; Bergmann, R.

  • Rapid Commun. Mass Spectrom 17 (2003):767-770

Autoradiographic imaging of the serotonin ransporter in the brain of rats and pigs using S-([18F]Fluoromethyl)-(+)-McN5652

Kretzschmar, M.; Brust, P.; Zessin, J.; Cumming, P.; Bergmann, R.; Johannsen, B.

  • European Neuropsychopharmacology 13 (2003) 387-397

Synthesis of 4-[18F]fluoroiodobenzene and its application in Sonogashira cross-coupling reactions

Wüst, F.; Knieß, T.

  • Journal of Labelled Compounds and Radiopharmaceuticals 2003, 46: 699-713
  • Lecture (Conference)
    15th International Symposium on Radiopharmaceutical Chemistry; Sydney, 07.-18.08.2003.

2002

Intraindividual comparison of two extracorporeal LDL apheresis methods: lipidfiltration and HELP

Julius, U.; Metzler, W.; Pietzsch, J.; Fassbender, T.; Klingel, R.

  • Int J Artif Organs 25 (2002): 1180-1188

Homocystein: Von der Spezialanalyse zum Routineparameter

Pietzsch, J.

  • Bioforum 9 (2002) 577-580

Synthesis and biological activity of ‚3+1' mixed ligand (3-thiapentane-1,5-dithiolato)oxorhenium(V) complexes bearing 1,2,3,4-tetrahydro(iso)quinoline and quinoline

Zablotskaya, A.; Segal, I.; Germane, S.; Shestakova, I.; Lukevics, E.; Knieß, T.; Spies, H.

  • Applied Organometallic Chemistry 16 (2002) 550-555

In vivo evidence for increased oxidation of circulating LDL in impaired glucose tolerance

Kopprasch, S.; Pietzsch, J.; Kuhlisch, E.; Fuecker, K.; Temelkova-Kurktschiev, T.; Hanefeld, M.; Kühne, H.; Julius, U.; Graessler, J.

  • Diabetes 51 (2002) 3102-3106

Synthesis of hydroxyl silylated rhenium and (99mTc)technetium ‚3+1'mixed ligand complexes

Knieß, T.; Spies, H.; Santos, I.; Zablotskaya, A.

  • J Label Compd Radiopharm 45 (2002) 629-636

Identification of tumor tissue by FTIR spectroscopy in combination with positron emission tomography

Richter, T.; Steiner, G.; Abu-Id, M. H.; Salzer, R.; Bergmann, R.; Rodig, H.; Johannsen, B.

  • Vibrational Spectroscopy 28 (2002) 103-110

Effect of hypoxia/hypercapnia on metabolism of 6-[18F]fluoro-L-DOPA in newborn piglets

Bauer, R.; Brust, P.; Walter, B.; Vorwieger, G.; Bergmann, R.; Elhalag, E.; Fritz, A.; Steinbach, J.; Füchtner, F.; Hinz, R.; Zwiener, U.; Johannsen, B.

  • Brain Research 934 (2002) 22-33

Impaired glucose tolerance is not associated with lipid intolerance

Henkel, E.; Temelkova-Kurtschiev, T.; Köhler, C.; Pietzsch, J.; Leonhardt, W.; Hanefeld, M.

  • Diab Nutr Metab 15 (2002) 84-90

Distribution of estrone sulfatase in rat brain determined by in vitro autoradiography with 16alpha-[18F]fluoroestradiol-3,17beta-disulfamate

Rodig, H.; Brust, P.; Römer, J.; Kasch, H.; Bergmann, R.; Füchtner, F.; Steinbach, J.; Johannsen, B.

  • Applied Radiation and Isotopes 56 (2002) 773-780

Distribution of 16alpha-[18F]fluoro-estradiol-3,17beta-disulfamate (FESDS) in rats, tumour-bearing mice and piglets

Brust, P.; Rodig, H.; Römer, J.; Kasch, H.; Bergmann, R.; Füchtner, F.; Zips, D.; Baumann, M.; Steinbach, J.; Johannsen, B.

  • Applied Radiation and Isotopes 57 (2002) 687-695

Biodistribution and catabolism of 18F-labeled neurotensin(8-13) analogs

Bergmann, R.; Scheunemann, M.; Heichert, C.; Mäding, P.; Wittrisch, H.; Kretzschmar, M.; Rodig, H.; Tourwé, D.; Iterbeke, K.; Chavatte, K.; Zips, D.; Reubi, J. C.; Johannsen, B.

  • Nuclear Medicine and Biology 29 (2002) 61-72

2001

Synthesis and physico-chemical characterization of triorganylsiloxyalkyl monodentate ligands with free mercapto group.

Zablotskaya, A.; Segal, I.; Lukevics, E.; Knieß, T.; Spies, H.

  • Latv. Kim. Z. N4 (2001) 339-342

Radio fluorination and positron emission tomography (PET) as a new approach to study the in vivo distribution and elimination of the advanced glycation endproducts Nepsilon-carboxymethyllysine (CML) and Nepsilon-carboxyethyllysine (CEL)

Bergmann, R.; Helling, R.; Heichert, C.; Scheunemann, M.; Mäding, P.; Wittrisch, H.; Johannsen, B.; Henle, T.

  • Nahrung/Food 45 (2001) 182-188

Intrauterine growth restriction induces up-regulation of cerebral aromatic amino acid decarboxylase activity in newborn piglets: [18F]fluorodopa positron-emission-tomographic study

Bauer, R.; Walter, B.; Vorwieger, G.; Bergmann, R.; Füchtner, F.; Brust, P.

  • Pediatric Research 49 (2001) 474-480

2000

Assessment of the in vitro and in vivo properties of a 99mTc-labeled inhibitor of the multidrug resistant gene product P-glycoprotein.

Bergmann, R.; Brust, P.; Scheunemann, M.; Pietzsch, H.-J.; Seifert, S.; Roux, F.; Johannsen, B.

  • Nucl. Med. Biol. 27 (2000) 135-141

Relation between brain tissue pO2 and dopamine synthesis of basal ganglia - A 18FDOPA-PET study in newborn piglets

Bauer, R.; Brust, P.; Walter, B.; Vorwieger, G.; Bergmann, R.; Füchtner, F.; Steinbach, J.; El-Hallag, E.; Fritz, A.; Johannsen, B.; Zwiener, U.

  • J. Perinat. Med. 28 (2000) 54-60

Functional expression of the serotonin transporter in immortalized rat brain microvessel endothelial cells

Brust, P.; Friedrich, A.; Krizbai, I. A.; Bergmann, R.; Roux, F.; Ganapathy, V.; Johannsen, B.

1999

Nicotinamide-substituted complexes as redox markers. 2. Synthesis of a 99Tc-dihydropyridine mixed-ligand complex and investigation of the stability in tissue homogenates

Rother, A.; Kniess, T.; Pütz, M.; Jungclas, H.; Spies, H.; Johannsen, B.

  • Journal of Labelled Compounds and Radiopharmaceuticals 42, 673-681(1999)

Effective coupling of Re/Tc-MAG3 complexes with amines and nucleobases in aprotic solvents.

Kniess, T.; Noll, S.; Noll, B.; Spies, H.; Johannsen, B.

Upregulation of the Aromatic Amino Acid Decarboxylase under Neonatal Asphyxia

Brust, P.; Bauer, R.; Vorieger, G.; Walter, B.; Bergmann, R.; Füchtner, F.; Steinbach, J.; Zwiener, U.; Johannsen, B.

Regional distribution of cerebral blood volume and cerebral blood flow in newborn piglets - effect of hypoxia / hypercapnia

Bauer, R.; Bergmann, R.; Walter, B.; Brust, P.; Zwiener, U.; Johannsen, B.

Nicotinamide-substituted complexes as redox markers 2. Synthesis of a 99Tc dihydropyridine mixed-ligand complex and investigation of the stability in tissue homogenates

Rother, A.; Knieß, T.; Pütz, M.; Jungclas, H.; Spies, H.; Johannsen, B.

  • J. Labelled Cpd. Radiopharm. 42 (1999) 673-681

1998

Mrp1 Multidrug Resistance-Associated Protein and P-Glykoprotein Expression in Rat Brain Microvessel Endothelial Cells

Regina, A.; Koman, A.; Piciotti, M.; El Hafny, B.; Center, M. S.; Bergmann, R.; Couraud, P.-O.; Roux, F.

Differentiation Between Specific and Nonspecific Effects Related to P-Glycoprotein Inhibition in Immortalized Rat Brain Endothelial Cells

Bergmann, R.; Brust, P.; Johannsen, B.

  • International Journal of Clinical Pharmacology and Therapeutics, Vol. 36, No. 1, 1998 (46-49)

Nicotinamide-Substituted Complexes as Redox Marker

Knieß, T.; Spies, H.; Brandau, W.; Johannsen, B.

Simultaneous Measurement of 18F-FDOPA Metabolism and Cerebral Blood Flow in Newborn Piglets

Brust, P.; Bauer, R.; Walter, B.; Bergmann, R.; Füchtner, F.; Vorwieger, G.; Steinbach, J.; Johannsen, B.; Zwiener, U.

1997

Uptake of 169Yb complexes in normal and tumour cells: influence of ligand and metabolic cell activity and stabilityx of cellular association

Kampf, G.; Knop, G.; Franke, W.-G.; Bergmann, R.; Johannsen, B.

  • Nucl. Med. Biol. 24 (1997) 349-355

1996

High-affinity binding of [3H]paroxetine to caudate nucleus and microvessels from porcine brain

Brust, P.; Bergmann, R.; Johannsen, B.

Rhenium(V) gluconate, a suitable precursor for the preparation of rhenium(V) complexes

Noll, B.; Knieß, T.; Friebe, M.; Spies, H.; Johannsen, B.

1995

Specific binding of (3H)imipramine indicates the presence of a specific serotonin transport system on endothelial cells of porcine brain

Brust, P.; Bergmann, R.; Johannsen, B.

Evaluation of Radioselenium Labeled Selenomethionine, a Potential Tracer for Brain Protein Synthesis by PET

Bergmann, R.; Brust, P.; Kampf, G.; Coenen, H. H.; Stöcklin, G.

1994

Studies of radiometal uptake by cultured normal and tumor cells

Kampf, G.; Knop, G.; Wenzel, U.; Wunderlich, G.; Bergmann, R.; Franke, W.-G.

  • European Journal of Nuclear Medicine 21 (1994) pp. 874

Beziehungen zwischen der 169Yb-Aufnahme in Normal- und Tumorzellen und deren metabolischer Aktivität in Abhängigkeit von der Ligandspezies

Kampf, G.; Knop, G.; Matys, S.; Kunz, G.; Wenzel, U.; Bergmann, R.; Franke, W.-G.

  • Nuklearmedizin 33 (1994) A 82

Characterization of serotonin uptake sites on the blood brain barrier

Brust, P.; Bergmann, R.

  • Journal of Neurochemistry 63 (1994) (Suppl. 1) S13C

Compartmental analysis of blood brain transfer and protein incorporation of L-[75Se]seleno methionine in rat brain

Bergmann, R.; Brust, P.; Coenen, H. H.; Stöcklin, G.

  • Journal of Neurochemistry 63 (1994) (Suppl. 1) S78C

Developmental changes of enzymes involved in peptide degradation in isolated rat brain microvessels

Brust, P.; Bech, A.; Kretzschmar, R.; Bergmann, R.

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