Hydrophilic oxybathophenanthroline ligands: Synthesis and copper(II) complexation
Hydrophilic oxybathophenanthroline ligands: Synthesis and copper(II) complexation
Stephan, H.; Juran, S.; Born, K.; Comba, P.; Geipel, G.; Hahn, U.; Werner, N.; Vögtle, F.
Hydrophilic oxybathophenanthroline dendrons (generation 1 to 3) have been synthesized by treatment of 4,7-bis(4´-hydroxyphenyl)-1,10-phenanthroline with the corresponding bromo-functionalized etheraryl branching units containing triethylene glycol monomethyl end groups. Radiotracer experiments using 64Cu prove the rapid formation of stable copper(II) complexes in aqueous solution. These 64Cu complexes remain unchanged even upon addition of a high excess of glutathion as competing ligand, thus demonstrating the high stability of the formed copper(II) complexes. Electronic and EPR spectroscopy indicate the formation of [Cu(L)2(OH2)2]2+ (L = Ligand) complexes in aqueous solution, confirmed by time-resolved laser fluorescence spectroscopy and supported by molecular mechanics modeling.
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New Journal of Chemistry 32(2008), 2016-2022
DOI: 10.1039/b805136d
Cited 8 times in Scopus
Permalink: https://www.hzdr.de/publications/Publ-10864