Ultrashort pulse laser accelerated proton beams for first radiobiological applications


Ultrashort pulse laser accelerated proton beams for first radiobiological applications

Schramm, U.; Zeil, K.; Richter, C.; Beyreuther, E.; Bussmann, M.; Cowan, T. E.; Enghardt, W.; Karsch, L.; Kluge, T.; Kraft, S.; Laschinsky, L.; Metzkes, J.; Naumburger, D.; Pawelke, J.; Sauerbrey, R.

We report on the generation of proton pulses with maximum energies exceeding 15MeV bymeans of the irradiation of few micron thick metal foils by ultrashort (30 fs) laser pulses at a power level of 100 TW. In contrast to the well known situation for longer laser pulses, here, a near linear scaling of the maximum proton energy with laser power can be found. Aiming for radiobiological applications the long and short term stability of the laser plasma accelerator as well as a compact energy selection and dosimetry system is presented. The first irradiation of in vitro tumour cells showing dose dependent biological damage is demonstrated paving the way for systematic radiobiological studies.

Keywords: laser proton acceleration; first cell irradiation

  • Contribution to proceedings
    14th Workshop on Advanced Accelerator Concepts, 13.-19.06.2010, Annapolis, MD, USA, USA
    AIP Conference Proceedings, Advanced Esselerator Concepts, 1299: AIP, 731

Permalink: https://www.hzdr.de/publications/Publ-14382