Crystal and solution structure of oxo rhenium(V) complexes with cysteine and cysteine methyl ester

The mono oxo rhenium(V) complexes of cysteine and cysteine methyl ester were synthesised via ligand exchange reaction starting from rhenium gluconate. Unexpectedly, the obtained oxo Re(V) complex with cysteine methyl ester was partially saponified. Both complexes were fully characterised by common analytical techniques in their solid state. Thus, an octahedral complex structure with 2(NH2,S) coordination in the equatorial plane and one carboxyl group bound trans to the oxo group is proven for both compounds by X-ray diffraction. Furthermore, the existence of a dioxo species at higher pH was proven for the first time with this type of ligands by determing the nearest coordination sphere of the rhenium centre in solution at a pH of 12 using extended x-ray absorption fine structure spectroscopy (EXAFS).