Partial Volume Correction of Cerebral Perfusion Estimates Obtained by Arterial Spin Labeling

Ambarki, K.; Petr, Jan; Wåhlin, A.; Wirestam, R.; Zarrinkoob, L.; Malm, J.; Eklund, A.

Partial Volume Correction of Cerebral Perfusion Estimates Obtained by Arterial Spin Labeling

Ambarki, K.; Petr, J.; Wåhlin, A.; Wirestam, R.; Zarrinkoob, L.; Malm, J.; Eklund, A.

Arterial Spin labeling (ASL) is a fully noninvasive MRI method capable to quantify cerebral perfusion. However, gray (GM) and white matter (WM) ASL perfusions are difficult to assess separately due to limited spatial resolution increasing the partial volume effects (PVE). In the present study, ASL PVE correction was implemented based on a regression algorithm in 22 healthy young men. PVE corrected perfusion of GM and WM were compared to previous studies. PVE-corrected GM perfusion was in agreement with literature values. In general, WM perfusion was higher despite the use of PVE correction.

Keywords: MRI; cerebral perfusion; gray and white matter; arterial spin labeling and healthy

Involved research facilities

PET-Center

Contribution to proceedings
16. NBC & 10. MTD 2014 joint conferences, 14.-16.10.2014, Gothenburg, Sweden
16th Nordic-Baltic Conference on Biomedical Engineering, IFMBE Proceedings: Springer International Publishing, 978-3-319-12966-2, 17-19
DOI: 10.1007/978-3-319-12967-9_5
Lecture (Conference)
16th Nordic-Baltic Conference on Biomedical Engineering, 14.-16.10.2014, Gothenburg, Sweden

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