CeO2-azacrown conjugate as a nanoplatform for combined radiopharmaceuticals

Khabirova, Sofia Yu.; Aleshin, Gleb Yu.; Plakhova, Tatiana V.; Zubenko, Anastasia D.; Shchukina, Anna A.; Fedorova, Olga A.; Averin, Aleksey A.; Belova, Ekaterina V.; Bazarkina, Elena F.; Kvashnina, Kristina O.; Kalmykov, Stepan N.

doi:10.3390/nano12244484

CeO2-azacrown conjugate as a nanoplatform for combined radiopharmaceuticals

Khabirova, S. Y.; Aleshin, G. Y.; Plakhova, T. V.; Zubenko, A. D.; Shchukina, A. A.; Fedorova, O. A.; Averin, A. A.; Belova, E. V.; Bazarkina, E. F.; Kvashnina, K. O.; Kalmykov, S. N.

This communication is one of the first attempts to assess CeO2 nanoparticles as a nanoplatform for radiopharmaceuticals with radionuclides. The process of functionalization using a bifunctional azacrown ligand is described, and the resulting conjugates are characterized by IR and Raman spectroscopy. Their complexes with 207Bi show a high stability in medically relevant media, thus encouraging the further study of these conjugates in vivo as potential combined radiopharmaceuticals

Involved research facilities

Rossendorf Beamline at ESRF DOI: 10.1107/S1600577520014265

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DOI: 10.1107/S1600577520014265 is cited by this (Id 34276) publication

Nanomaterials 12(2022), 4484
DOI: 10.3390/nano12244484
Cited 4 times in Scopus

Permalink: https://www.hzdr.de/publications/Publ-34276