Data publication: Development and Biological Evaluation of the First Highly Potent and Specific Benzamide-Based Radiotracer [¹⁸F]BA3 for Imaging of Histone Deacetylases 1 and 2 in Brain
Data publication: Development and Biological Evaluation of the First Highly Potent and Specific Benzamide-Based Radiotracer [¹⁸F]BA3 for Imaging of Histone Deacetylases 1 and 2 in Brain
Clauß, O.; Schäker-Hübner, L.; Wenzel, B.; Toussaint, M.; Deuther-Conrad, W.; Gündel, D.; Teodoro, R.; Dukic-Stefanovic, S.; Ludwig, F.-A.; Kopka, K.; Brust, P.; Hansen, F. K.; Scheunemann, M.
The data publication contain: 1) Radiosynthesis data (Scheme of the synthesis module; RP-HPLC chromatograms of formulated [18F]BA3; MLC chromatograms of in vivo metabolism studies) 2) Biological data (Baseline TAC of CD-1 mice brain, biodistribution after i.v. injection of [18F]BA3) 3) Analytical data (1H, 13C, 19F NMR spectra; LC-MS chromatograms for final products)
Keywords: histone deacetylase inhibitor; HDAC1/2-specific; radiochemistry; fluorine-18 labelling; positron emission tomography (PET); brain-penetration; glioblastoma; glioma
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- DOI: 10.3390/ph15030324 references this (Id 34366) publication
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Development and Biological Evaluation of the First Highly Potent and Specific …
ROBIS: 34169 has used this (Id 34366) publication of HZDR-primary research data
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Reseach data in the HZDR data repository RODARE
Publication date: 2022-03-10 Open access
DOI: 10.14278/rodare.1474
Versions: 10.14278/rodare.1507 | 10.14278/rodare.1475
License: CC-BY-4.0
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Permalink: https://www.hzdr.de/publications/Publ-34366
