Synthesis and biological activity of 3+1' mixed ligand (3-thiapentane-1,5-dithiolato)oxorhenium(V) complexes bearing 1,2,3,4-tetrahydro(iso)quinoline and quinoline
Synthesis and biological activity of 3+1' mixed ligand (3-thiapentane-1,5-dithiolato)oxorhenium(V) complexes bearing 1,2,3,4-tetrahydro(iso)quinoline and quinoline
Zablotskaya, A.; Segal, I.; Germane, S.; Shestakova, I.; Lukevics, E.; Knieß, T.; Spies, H.
3+1' mixed ligand oxorhenium(V) complexes of the type ReO(SSS)S(CH2)nHetN have been synthesized by the reaction of the preliminary prepared tetrahydro(iso)quinolyl containing monodentate ligands with chloro(3-thiapentate-1,5-dithiolato)oxorhenium(V). The newly synthesized ligands and complexes were characterized by elemental analysis, IR, 1H, and 13C NMR spectroscopy. Metal complexes were screened for psychotropic and antitumour activities and receptor-binding properties and were found to be active in this respect.
Keywords: oxorhenium complexes; tetrahydroquinoline; tetrahydroisoquinoline; quinoline; 3-thiapentane-1,5-dithiolate; psychotropic activity; antitumour activity; receptor-binding porperties; NMR spectra, toxicity
- Applied Organometallic Chemistry 16 (2002) 550-555
Permalink: https://www.hzdr.de/publications/Publ-5076
