Medical application of secondary beams.

In the application of positron emitting secondary beams to the verification of heavy ion treatment planning, the implanted radioactive isotopes undergo metabolism. Experiments on rabbit thigh muscle were performed using ¹¹C secondary beams from HIMAC. PET allows us three-dimensional imaging of the implanted ¹¹C, however, the early phase cannot be measured. The positron camera allows us in-situ measurement. By focusing the beam to narrow region, time-activity analysis of the volume of interest revealed the existence of faster metabolic component.