Azaspirovesamicols-Regioselective Synthesis and Crystal Structure Analysis of a Novel Class of Vesamicol Analogues as Potential Ligands for the Vesicular Acetylcholine Transporter
Azaspirovesamicols-Regioselective Synthesis and Crystal Structure Analysis of a Novel Class of Vesamicol Analogues as Potential Ligands for the Vesicular Acetylcholine Transporter
Wenzel, B.; Bats, J. W.; Scheunemann, M.; Steinbach, J.
This report describes the high regioselectivity of nucleophilic epoxide ring-opening reactions which resulted in two of four possible regioisomers of N-benzoyl- (5a and 5b) and N-fluorobenzoylazaspirovesamicol derivatives (6a and 6b), respectively. Based on structural information obtained from X-ray crystal structure analyses of 5a and 5b the mode of epoxide ring-opening is discussed
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Chemistry Letters 36(2007)2, 276-277
DOI: 10.1246/cl.2007.276
Cited 3 times in Scopus
Permalink: https://www.hzdr.de/publications/Publ-9373