Publications of Institute of Radiopharmaceutical Cancer Research
1322 Publications2012
Radiohalogenated 4-anilinoquinazoline-based EGFR-TK inhibitors as potential cancer imaging agents
Neto, C.; Fernandes, C.; Oliveira, M. C.; Gano, L.; Mendes, F.; Kniess, T.; Santos, I.
Involved research facilities
- PET-Center
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Nuclear Medicine and Biology 39(2012), 247-260
DOI: 10.1016/j.nucmedbio.2011.09.001
Cited 12 times in Scopus
Ecto-ATPase inhibition: ATP and adenosine release under physiological and ischemic in vivo conditions in the rat striatum
Melani, A.; Corti, F.; Stephan, H.; Müller, C. E.; Donati, C.; Bruni, P.; Vannucchi, M. G.; Pedata, F.
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Experimental Neurology 233(2012), 193-204
DOI: 10.1016/j.expneurol.2011.09.036
Cited 84 times in Scopus
Study of differences in the VEGFR2 inhibitory activities between semaxanib and SU5205 using 3D-QSAR, docking, and molecular dynamics simulations
Munoza, C.; Adasmea, F.; Alzate-Morales, J. H.; Vergara-Jaquea, A.; Kniess, T.; Caballero, J.
Involved research facilities
- PET-Center
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Journal of Molecular Graphics and Modelling 32(2012), 39-48
DOI: 10.1016/j.jmgm.2011.10.005
Cited 45 times in Scopus
Radiolabeled small molecule inhibitors of VEGFR – recent advances
Kniess, T.
Involved research facilities
- PET-Center
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Current Pharmaceutical Design 18(2012), 2867-2874
DOI: 10.2174/138161212800672796
ISSN: 1873-4286
Cited 7 times in Scopus
Module-assisted preparation of 64Cu with high specific activity
Thieme, S.; Walther, M.; Pietzsch, H.-J.; Henniger, J.; Preusche, S.; Mäding, P.; Steinbach, J.
Involved research facilities
- PET-Center
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Applied Radiation and Isotopes 70(2012), 602-608
Online First (2012) DOI: 10.1016/j.apradiso.2012.01.019
Cited 71 times in Scopus
SUV-measurements and patient-specific corrections thereof in pediatric Hodgkin-lymphoma: Is there a benefit for PPV in early response assessment by FDG-PET?
Furth, C.; Meseck, R. M.; Steffen, I. G.; Schoenberger, S.; Denecke, T.; Henze, G.; Hautzel, H.; Hofheinz, F.; Großer, O.; Hundsdoerfer, P.; Amthauer, H.; Ruf, J.
Involved research facilities
- PET-Center
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Pediatric Blood & Cancer 59(2012), 475-480
DOI: 10.1002/pbc.24047
Cited 14 times in Scopus
Automatic volume delineation in oncological PET. Evaluation of a dedicated software tool and comparison with manual delineation in clinical data sets
Hofheinz, F.; Pötzsch, C.; Oehme, L.; Beuthien-Baumann, B.; Steinbach, J.; Kotzerke, J.; van den Hoff, J.
Involved research facilities
- PET-Center
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Nuklearmedizin 51(2012), 9-16
DOI: 10.3413/Nukmed-0419-11-07
ISSN: 0029-5566
Cited 92 times in Scopus
Synthesis and Molecular Structure of tert-Butyl 4-(2-tert-butoxy-2-oxoethyl)piperazine-1-carboxylate
Mamat, C.; Flemming, A.; Köckerling, M.
Involved research facilities
- PET-Center
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Crystals 2(2012), 90-95
DOI: 10.3390/cryst2010090
ISSN: 2073-4352
Cited 2 times in Scopus
The Synthesis and Molecular Structure of 2-(4-Methoxybenzyl)-4-nitro-2H-indazole
Ebert, K.; Köckerling, M.; Mamat, C.
Involved research facilities
- PET-Center
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Crystals 2(2012), 176-181
DOI: 10.3390/cryst2020176
Cited 1 times in Scopus
Specific targeting of hypoxic tumor tissue with nitroimidazole-peptide conjugates
Splith, K.; Bergmann, R.; Pietzsch, J.; Neundorf, I.
Involved research facilities
- PET-Center
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ChemMedChem 7(2012), 57-61
DOI: 10.1002/cmdc.201100401
Cited 21 times in Scopus
Pyrrolovesamicols - Synthesis, structure and VAChT binding of two 4-fluorobenzoyl regioisomers
Wenzel, B.; Li, Y.; Kraus, W.; Sorger, D.; Sabri, O.; Brust, P.; Steinbach, J.
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Bioorganic & Medicinal Chemistry Letters 22(2012), 2163-2166
DOI: 10.1016/j.bmcl.2012.01.127
Cited 8 times in Scopus
The Molecular Structure of 1,2:5,6-Di-O-isopropylidene-3-O-toluenesulfonyl-a-D-glucofuranose
Mamat, C.; Peppel, T.; Köckerling, M.
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Crystals 2(2012), 105-109
DOI: 10.3390/cryst2010105
ISSN: 2073-4352
Cited 6 times in Scopus
Imaging of the brain serotonin transporters (SERT) with 18F-labelled fluoromethyl-McN5652 and PET in humans
Hesse, S.; Brust, P.; Mäding, P.; Becker, G.-A.; Seese, A.; Patt, M.; Sorger, D.; Zessin, J.; Sacher, J.; Lobsien, D.; Habermann, B.; Meyer, P. M.; Füchtner, F.; Luthardt, J.; Bresch, A.; Steinbach, J.; Sabri, O.
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European Journal of Nuclear Medicine and Molecular Imaging 39(2012)6, 1001-1011
Online First (2012) DOI: 10.1007/s00259-012-2078-z
Cited 29 times in Scopus
Development of radioligands for α7-nAChR imaging with positron emission tomography
Brust, P.; Peters, D.; Deuther-Conrad, W.
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Current Drug Targets 13(2012)5, 594-601
DOI: 10.2174/138945012800398955
ISSN: 1389-4501
Cited 28 times in Scopus
Synthesis, radiofluorination and pharmacological evaluation of fluoromethyl substituted spirocyclic PET tracers for labeling of σ1 receptors in the central nervous system and comparison with longer homologues
Maisonial, A.; Grosse Maestrup, E.; Wiese, C.; Hiller, A.; Schepmann, D.; Deuther-Conrad, W.; Fischer, S.; Brust, P.; Wünsch, B.
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Bioorganic & Medicinal Chemistry 20(2012), 257-269
DOI: 10.1016/j.bmc.2011.11.002
Cited 21 times in Scopus
Radiosynthesis and Radiotracer Properties of a 7-(2-[F-18]Fluoroethoxy)-6-methoxy-pyrrolidinylquinazoline for Imaging of Phosphodiesterase 10A with PET
Funke, U.; Deuther-Conrad, W.; Schwan, G.; Maisonial, A.; Scheunemann, M.; Fischer, S.; Hiller, A.; Briel, D.; Brust, P.
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Pharmaceuticals 5(2012)2, 169-188
Online First (2012) DOI: 10.3390/ph5020169
ISSN: 1424-8247
Cited 16 times in Scopus
Site-selective radiolabeling of peptides by 18F-fluorobenzoylation with [18F]SFB in solution and on solid phase - a comparative study
Kuchar, M.; Pretze, M.; Knieß, T.; Steinbach, J.; Pietzsch, J.; Löser, R.
Involved research facilities
- PET-Center
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Amino Acids 43(2012), 1431-1443
Online First (2012) DOI: 10.1007/s00726-012-1216-z
Cited 31 times in Scopus
Effect of leukotriene inhibitors on evolution of experimental brain contusions
Voigt, C. L. M.; Donat, C. K.; Härtig, W.; Förschler, A.; Arendt, T.; Meixensberger, J.; Schuhmann, M. U.
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Neuropathology and Applied Neurobiology 38(2012)4, 354-366
DOI: 10.1111/j.1365-2990.2011.01211.x
Cited 10 times in Scopus
Radiosynthesis of a 18F-labeled 2,3-diarylsubstituted indole via McMurry coupling for functional characterization of cyclooxygenase-2 (COX-2) in vitro and in vivo
Kniess, T.; Laube, M.; Bergmann, R.; Graf, F.; Steinbach, J.; Wuest, F.; Pietzsch, J.
Involved research facilities
- PET-Center
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Bioorganic & Medicinal Chemistry 20(2012), 3410-3421
Online First (2012) DOI: 10.1016/j.bmc.2012.04.022
Cited 44 times in Scopus
2011
Suitability of bilateral filtering for edge-preserving noise reduction in PET
Hofheinz, F.; Langner, J.; Beuthien-Baumann, B.; Oehme, L.; Steinbach, J.; Kotzerke, J.; van den Hoff, J.
Involved research facilities
- PET-Center
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EJNMMI Research 1(2011)23
DOI: 10.1186/2191-219X-1-23
Cited 54 times in Scopus
Synthesis of an 18F-labeled cyclin-dependent kinase-2 inhibitor
Svensson, F.; Kniess, T.; Bergmann, R.; Pietzsch, J.; Wuest, F.
Involved research facilities
- PET-Center
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Journal of Labelled Compounds and Radiopharmaceuticals 54(2011), 769-774
DOI: 10.1002/jlcr.1922
Cited 2 times in Scopus
S100A2 in cancerogenesis: a friend or a foe?
Wolf, S.; Haase-Kohn, C.; Pietzsch, J.
Involved research facilities
- PET-Center
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Amino Acids 41(2011), 849-861
DOI: 10.1007/s00726-010-0623-2
Cited 56 times in Scopus
S100 proteins in health and disease
Pietzsch, J.
Involved research facilities
- PET-Center
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Amino Acids 41(2011), 755-760
DOI: 10.1007/s00726-010-0816-8
Cited 21 times in Scopus
Influence of storage on the position of the germinal disc in the fertilized unincubated chicken egg
Burkhardt, A.; Meister, S.; Bergmann, R.; Koch, E.
Involved research facilities
- PET-Center
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Poultry Science 90(2011), 2169-2173
DOI: 10.3382/ps.2010-01179
ISSN: 0032-5791
Cited 9 times in Scopus
Synthesis, colloidal stability and 64Cu labeling of iron oxide nanoparticles bearing different macrocyclic ligands
Barreto, J. A.; Matterna, M.; Graham, B.; Stephan, H.; Spiccia, L.
- New Journal of Chemistry 35(2011), 2705-2712
Copper-mediated cross-linking of S100A4, but not of S100A2, results in proinflammatory effects in melanoma cells
Haase-Kohn, C.; Wolf, S.; Lenk, J.; Pietzsch, J.
Involved research facilities
- PET-Center
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Biochemical and Biophysical Research Communications 413(2011), 494-498
DOI: 10.1016/j.bbrc.2011.08.132
Cited 30 times in Scopus
Phosphopeptides with improved cellular uptake properties as ligands for the polo-box domain of polo-like kinase 1
Richter, S.; Neundorf, I.; Loebner, K.; Gräber, M.; Berg, T.; Bergmann, R.; Steinbach, J.; Pietzsch, J.; Wuest, F.
Involved research facilities
- PET-Center
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Bioorganic & Medicinal Chemistry Letters 21(2011), 4686-4689
DOI: 10.1016/j.bmcl.2011.06.103
Cited 7 times in Scopus
Comparison of dopamine turnover, dopamine influx constant and activity ratio of striatum and occipital brain with F-18-dopa brain PET in normal controls and patients with Parkinson's disease
Oehme, L.; Perick, M.; Beuthien-Baumann, B.; Wolz, M.; Storch, A.; Loehe, M.; Herting, B.; Langner, J.; van den Hoff, J.; Reichmann, H.; Kotzerke, J.
Involved research facilities
- PET-Center
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European Journal of Nuclear Medicine and Molecular Imaging 38(2011), 1550-1559
DOI: 10.1007/s00259-011-1819-8
ISSN: 1619-7070
Cited 21 times in Scopus
Impact of functionalized coligands on the pharmacokinetics of 99mTc(III) ‘4+1’ mixed-ligand complexes conjugated to bombesin
Künstler, J.-U.; Bergmann, R.; Gniazdowska, E.; Kozminski, P.; Walther, M.; Pietzsch, H.-J.
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Journal of Inorganic Biochemistry 105(2011), 1383-1390
DOI: 10.1016/j.jinorgbio.2011.07.002
Cited 13 times in Scopus
Neue Entwicklungen in der PET/CT Hybridbildgebung: Nutzen für die Strahlentherapie?
Hofheinz, F.; Perrin, R.; van den Hoff, J.; Zips, D.
Involved research facilities
- PET-Center
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Der Nuklearmediziner 34(2011), 79-87
DOI: 10.1055/s-0031-1280770
Radiolabeling of phosphatidylserine-binding peptides with prosthetic groups N-[6-(4-[18F]fluorobenzylidene)aminooxyhexyl]maleimide ([18F]FBAM) and N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB)
Kapty, J.; Kniess, T.; Wuest, F.; Mercer, J. R.
Involved research facilities
- PET-Center
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Applied Radiation and Isotopes 69(2011), 1218-1225
DOI: 10.1016/j.apradiso.2011.05.012
ISSN: 0969-8043
Cited 25 times in Scopus
Leitlinie für PET und SPECT–Untersuchungen von Hirntumoren mit radioaktiv markierten Aminosäuren
Langen, K.-J.; Bartenstein, P.; Brust, P.; Coenen, H. H.; Drzezga, A.; Grünwald, F.; Krause, B. J.; Kuwert, T.; Sabri, O.; Tatsch, K.; Weber, W. A.; Schreckenberger, M.
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Nuklearmedizin 50(2011)4, 167-173
DOI: 10.3413/nuk-2011041
Cited 87 times in Scopus
Maleimido-Functionalized NOTA Derivatives as Bifunctional Chelators for Site-Specific Radiolabeling
Förster, C.; Schubert, M.; Pietzsch, H.-J.; Steinbach, J.
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Molecules 16(2011), 5228-5240
DOI: 10.3390/molecules16065228
ISSN: 1420-3049
Cited 10 times in Scopus
Long-Acting Lipidated Analogue of Human Pancreatic Polypeptide Is Slowly Released into Circulation
Bellmann-Sickert, K.; Elling, C. E.; Madsen, A. N.; Little, P. B.; Lundgren, K.; Gerlach, L.-O.; Bergmann, R.; Holst, B.; Schwartz, T. W.; Beck-Sickinger, A. G.
Involved research facilities
- PET-Center
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Journal of Medicinal Chemistry 54(2011)8, 2658-2667
DOI: 10.1021/jm101357e
ISSN: 0022-2623
Cited 66 times in Scopus
Synthesis, characterization and biological evaluation of [188Re(N)(cys∼)(PNP)]+/0 mixed-ligand complexes as prototypes for the development of 188Re(N)-based target-specific radiopharmaceuticals
Thieme, S.; Agostini, S.; Bergmann, R.; Pietzsch, J.; Pietzsch, H.-J.; Carta, D.; Salvarese, N.; Refosco, F.; Bolzati, C.
Involved research facilities
- PET-Center
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Nuclear Medicine and Biology 38(2011), 399-415
DOI: 10.1016/j.nucmedbio.2010.09.006
Cited 13 times in Scopus
Feasibility and performance of novel software to quantify metabolically active volumes and 3D partial volume corrected SUV and metabolic volumetric products of spinal bone marrow metastases on 18F-FDG-PET/CT.
Torigian, D. A.; Lopez, R. F.; Alapati, S.; Bodapati, G.; Hofheinz, F.; van den Hoff, J.; Saboury, B.; Alavi, A.
Involved research facilities
- PET-Center
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Hellenic Journal of Nuclear Medicine 14(2011)1, 8-14
ISSN: 1108-1430
Visualization of the focus in congenital hyperinsulinism by intraoperative sonography
von Rohden, L.; Mohnike, K.; Mau, H.; Eberhard, T.; Mohnike, W.; Blankenstein, O.; Empting, S.; Koch, M.; Fuechtner, F.; Barthlen, W.
Involved research facilities
- PET-Center
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Seminars in Pediatric Surgery 20(2011)1, 28-31
DOI: 10.1053/j.sempedsurg.2010.10.011
ISSN: 1055-8586
Cited 12 times in Scopus
Cathepsin S inhibitors: WO2010070615
Löser, R.
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Expert Opinion on Therapeutic Patents 21(2011)4, 585-591
DOI: 10.1517/13543776.2011.550574
ISSN: 1354-3776
Cited 3 times in Scopus
Synthesis and evaluation of 1,5-diaryl-substituted tetrazoles as novel selective cyclooxygenase-2 (COX-2) inhibitors
Al-Hourani, B. J.; Sharma, S. K.; Mane, J. Y.; Tuszynski, J.; Baracos, V.; Kniess, T.; Suresh, M.; Pietzsch, J.; Wuest, F.
Involved research facilities
- PET-Center
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Bioorganic & Medicinal Chemistry Letters 21(2011), 1823-1826
DOI: 10.1016/j.bmcl.2011.01.057
ISSN: 0960-894X
Cited 82 times in Scopus
Imidazole Containing Bispidine Ligands: Synthesis, Structure and Cu(II)-Complexation
Walther, M.; Matterna, M.; Juran, S.; Fähnemann, S.; Stephan, H.; Kraus, W.; Emmerling, F.
- Zeitschrift für Naturforschung Section B - A Journal of Chemical Sciences 66b(2011), 721-728
Expression, purification and fluorine-18 radiolabeling of recombinant S100A4: a potential probe for molecular imaging of receptor for advanced glycation endproducts in vivo?
Wolf, S.; Haase-Kohn, C.; Lenk, J.; Hoppmann, S.; Bergmann, R.; Steinbach, J.; Pietzsch, J.
Involved research facilities
- PET-Center
- Amino Acids 41(2011), 809-820
Zwei oder vier Stunden [18F]FMISO-PET in Kopf-Hals-Karzinomen: Wann ist der Bildkontrast am höchsten?
Abolmaali, N.; Haase, R.; Koch, A.; Zips, D.; Steinbach, J.; Baumann, M.; Kotzerke, J.; Zöphel, K.
Involved research facilities
- PET-Center
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Nuklearmedizin 50(2011), 22-27
DOI: 10.3413/nukmed-00328-10-07
Cited 45 times in Scopus
Intraoperative Sonography: A Technique for Localizing Focal Forms of Congenital Hyperinsulinism in the Pancreas
von Rohden, L.; Mohnike, K.; Mau, H.; Eberhard, T.; Mohnike, W.; Blankenstein, O.; Empting, S.; Koch, M.; Füchtner, F.; Barthlen, W.
Involved research facilities
- PET-Center
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Ultraschall in der Medizin 32(2011), 74-80
DOI: 10.1055/s-0029-1245598
Cited 12 times in Scopus
A 18F-labeled Fluorobutyl-substituted spirocyclic piperidine derivative as a selective radioligand for PET imaging of sigma1 receptors
Maisonial, A.; Große Maestrup, E.; Fischer, S.; Hiller, A.; Scheunemann, M.; Wiese, C.; Schepmann, D.; Steinbach, J.; Deuther-Conrad, W.; Wünsch, B.; Brust, P.
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ChemMedChem 6(2011), 1401-1410
DOI: 10.1002/cmdc.201100108
Cited 21 times in Scopus
A Novel Tetrabranched Neurotensin(8-13) Cyclam Derivative: Synthesis, 64Cu-Labeling and Biological Evaluation
Röhrich, A.; Bergmann, R.; Kretzschmann, A.; Noll, S.; Steinbach, J.; Pietzsch, J.; Stephan, H.
Involved research facilities
- PET-Center
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Journal of Inorganic Biochemistry 105(2011), 821-832
DOI: 10.1016/j.jinorgbio.2011.02.011
Cited 21 times in Scopus
Nanomaterials: applications in cancer imaging and therapy
Barreto, J. A.; O'Malley, W.; Kubeil, M.; Graham, B.; Stephan, H.; Spiccia, L.
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Advanced Materials 23(2011)12, H18-H40
DOI: 10.1002/adma.201190041
Synthesis, structure determination and (radio-) fluorination of novel functionalized phosphanes suitable for the traceless Staudinger ligation
Mamat, C.; Franke, M.; Peppel, T.; Köckerling, M.; Steinbach, J.
Involved research facilities
- PET-Center
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Tetrahedron 67(2011), 4521-4529
DOI: 10.1016/j.tet.2011.04.091
Cited 19 times in Scopus
Synthesis and biological evaluation of new [Tc(N)(PS)]-based mixed-ligand compounds useful in design of target-specific radiopharmaceuticas: the 2-methoxyphenylpiperazine dithiocarbamate derivatives as example
Bolzati, C.; Salvarese, N.; Carta, D.; Refosco, F.; Dolmella, A.; Pietzsch, H.-J.; Bergmann, R.; Bandoli, G.
Involved research facilities
- PET-Center
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Journal of Biological Inorganic Chemistry 16(2011), 137-155
DOI: 10.1007/s00775-010-0712-4
Cited 14 times in Scopus
[18F]1-(3-fluoropropyl)piperazines as model compounds for the radiofluorination of pyrido[2,3-d]pyrimidines
Grosse-Gehling, P.; Wuest, F. R.; Peppel, T.; Köckerling, M.; Mamat, C.
Involved research facilities
- PET-Center
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Radiochimica Acta 99(2011), 365-373
DOI: 10.1524/ract.2011.1834
Cited 8 times in Scopus
Synthesis and biological evaluation of novel 4-benzylpiperazine ligands for sigma-1 receptor imaging
Li, Z.-J.; Ren, H.-Y.; Cui, M.-C.; Deuther-Conrad, W.; Tang, R.-K.; Steinbach, J.; Brust, P.; Liu, B.-L.; Jia, H.-M.
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Bioorganic & Medicinal Chemistry 19(2011)9, 2911-2917
DOI: 10.1016/j.bmc.2011.03.037
Cited 13 times in Scopus
Cross-Coupling Reactions as Valuable Tool for the Preparation of PET Radiotracers
Pretze, M.; Große-Gehling, P.; Mamat, C.
Involved research facilities
- PET-Center
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Molecules 16(2011), 1129-1165
DOI: 10.3390/molecules16021129
Cited 44 times in Scopus
In vitro binding profile and radiosynthesis of a novel 18F-labeled azaspirovesamicol analog as potential ligand for imaging of the vesicular acetylcholine transporter
Wenzel, B.; Hiller, A.; Fischer, S.; Sorger, D.; Deuther-Conrad, W.; Scheunemann, M.; Brust, P.; Sabri, O.; Steinbach, J.
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Journal of Labelled Compounds and Radiopharmaceuticals 54(2011), 426-432
DOI: 10.1002/jlcr.1891
Cited 8 times in Scopus
High regiocontrol in the nucleophilic ring opening of 1-aralkyl-3,4-epoxypiperidines with amines – A short-step synthesis of 4-fluorobenzyltrozamicol and novel anilidopiperidines
Scheunemann, M.; Hennig, L.; Funke, U.; Steinbach, J.
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Tetrahedron 67(2011), 3448-3456
DOI: 10.1016/j.tet.2011.03.045
Cited 18 times in Scopus
Assessment of alpha 7 nicotinic acetylcholine receptor availability in juvenile pig brain with [18F]NS10743
Deuther-Conrad, W.; Fischer, S.; Hiller, A.; Becker, G.; Cumming, P.; Xiong, G.; Funke, U.; Sabri, O.; Peters, D.; Brust, P.
- European Journal of Nuclear Medicine and Molecular Imaging 38(2011)8, 1541-1549
Automated radiosynthesis of the thiol-reactive labeling agent N-[6-(4-[18F]fluorobenzylidene)aminooxyhexyl]maleimide ([18F]FBAM)
Knieß, T.; Kuchar, M.; Pietzsch, J.
Involved research facilities
- PET-Center
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Applied Radiation and Isotopes 69(2011), 1226-1230
DOI: 10.1016/j.apradiso.2011.03.043
Cited 14 times in Scopus
Synthesis, pharmacological activity and structure affinity relationships of spirocyclic σ1 receptor ligands with a (2-fluoroethyl) residue in 3-position
Große Maestrup, E.; Wiese, C.; Schepmann, D.; Brust, P.; Wünsch, B.
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Bioorganic & Medicinal Chemistry 19(2011), 393-405
DOI: 10.1016/j.bmc.2010.11.013
Cited 40 times in Scopus
The serotonin transporter availability in untreated early-onset and late-onset patients with obsessive-compulsive disorder
Hesse, S.; Stengler, K.; Regenthal, R.; Patt, M.; Becker, G.-A.; Franke, A.; Knüpfer, H.; Meyer, P. M.; Luthardt, J.; Jahn, I.; Lobsien, D.; Heinke, W.; Brust, P.; Hegerl, U.; Sabri, O.
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International Journal of Neuropsychopharmacology 14(2011), 1-12
DOI: 10.1017/S1461145710001604
Cited 53 times in Scopus
Molecular imaging of σ receptors: synthesis and evaluation of the potent σ1 selective radioligand [18F]fluspidine
Fischer, S.; Wiese, C.; Grosse Maestrup, E.; Hiller, A.; Deuther-Conrad, W.; Scheunemann, M.; Schepmann, D.; Steinbach, J.; Wünsch, B.; Brust, P.
- European Journal of Nuclear Medicine and Molecular Imaging 38(2011)3, 540-551
Traumatic Brain Injury Elicits Similar Alterations in α7 Nicotinic Receptor Density in Two Different Experimental Models
Hoffmeister, P.-G.; Donat, C. K.; Schuhmann, M. U.; Voigt, C.; Walter, B.; Nieber, K.; Meixensberger, J.; Bauer, R.; Brust, P.
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Neuromolecular Medicine 13(2011)1, 44-53
DOI: 10.1007/s12017-010-8136-4
ISSN: 1535-1084
Cited 30 times in Scopus
Enantioselective σ1 receptor binding and biotransformation of the spirocyclic PET tracer 1’-Benzyl-3-(3-fluoropropyl)-3H-spiro[[2]benzofuran-1,4’-piperidine]
Wiese, C.; Große Maestrup, E.; Schepmann, D.; Grimme, S.; Humpf, H.-U.; Brust, P.; Wünsch, B.
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Chirality 23(2011), 148-154
DOI: 10.1002/chir.20893
Cited 11 times in Scopus
Design, Synthesis and Preliminary in vitro and in vivo Pharmacological Evaluation of 2-{4-[4-(2,5-disubstituted thiazolyl)phenylethyl] piperazin-1-yl}-1,8-naphthyridine-3- carbonitriles as Atypical Antipsychotic Agents
Chandra Sekhar, K. V. G.; Rao, V. S.; Deuther-Conrad, W.; Reddy, A. S.; Brust, P.; Kumara, M. M. K.
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Journal of Enzyme Inhibition And Medicinal Chemistry 26(2011)4, 561-568
DOI: 10.3109/14756366.2010.537658
Cited 4 times in Scopus
Implementation of 89Zr production and in vivo imaging of B-cells in mice with 89Zr-labeled anti B-cell antibodies by small animal PET/CT
Walther, M.; Gebhardt, P.; Grosse-Gehling, P.; Würbach, L.; Irmler, I.; Preusche, S.; Khalid, M.; Opfermann, T.; Kamradt, T.; Steinbach, J.; Saluz, H.-P.
Involved research facilities
- PET-Center
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Applied Radiation and Isotopes 69(2011), 852-857
DOI: 10.1016/j.apradiso.2011.02.040
Cited 37 times in Scopus
2010
Positron emission tomography 2008 in Germany: Results of the query and current status
Kotzerke, J.; Oehme, L.; Lindner, O.; Hellwig, D.; Bartenstein, P.; Baum, R. P.; Burchert, W.; Dietlein, M.; Haberkorn, U.; Kluge, R.; Knapp, W. H.; Kuwert, T.; Nitzsche, E.; Reske, S. N.; Reuland, P.; Schicha, H.; Schober, O.; Schwaiger, M.; van den Hoff, J.
Involved research facilities
- PET-Center
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Nuklearmedizin 49(2010)2, 58-64
DOI: 10.3413/nukmed-0203
ISSN: 0029-5566
Cited 23 times in Scopus
Combined correction of recovery effect and motion blur for SUV quantification of solitary pulmonary nodules in FDG PET/CT
Apostolova, I.; Wiemker, R.; Paulus, T.; Kabus, S.; Dreilich, T.; van den Hoff, J.; Plotkin, M.; Mester, J.; Brenner, W.; Burchert, R.; Klutmann, S.
Involved research facilities
- PET-Center
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European Radiology 20(2010)8, 1868-1877
DOI: 10.1007/s00330-010-1747-1
ISSN: 0938-7994
Cited 28 times in Scopus
Modulation of Adrenal Aldosterone Release by Oxidative Modification of Low-Density Lipoprotein
Ansurudeen, I.; Pietzsch, J.; Graessler, J.; Ehrhart-Bornstein, M.; Saha, S.; Bornstein, S. R.; Kopprasch, S.
Involved research facilities
- PET-Center
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American Journal of Hypertension 23(2010)10, 1061-1068
DOI: 10.1038/ajh.2010.118
ISSN: 0895-7061
Cited 8 times in Scopus
Identification of transport processes in bioirrigated muddy sediments by [18F]fluoride PET (Positron Emission Tomography)
Roskosch, A.; Lewandowski, J.; Bergmann, R.; Wilke, F.; Brenner, W.; Burchert, R.
Involved research facilities
- PET-Center
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Applied Radiation and Isotopes 68(2010)6, 1094-1097
DOI: 10.1016/j.apradiso.2010.02.004
Cited 7 times in Scopus
Noncovalent Tripeptidyl Benzyl- and Cyclohexyl-Amine Inhibitors of the Cysteine Protease Caspase-1
Löser, R.; Abbenante, G.; Madala, P. K.; Halili, M.; Le, G. T.; Fairlie, D. P.
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Journal of Medicinal Chemistry 53(2010), 2651-2655
DOI: 10.1021/jm901790w
Cited 12 times in Scopus
Antimalarial activity of azadipeptide nitriles
Löser, R.; Gut, J.; Rosenthal, P. J.; Frizler, M.; Gütschow, M.; Andrews, K. T.
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Bioorganic & Medicinal Chemistry Letters 20(2010), 252-255
DOI: 10.1016/j.bmcl.2009.10.122
Cited 11 times in Scopus
Sugar-decorated dendritic nanocarriers: Encapsulation and release of the octahedral rhenium cluster complex [Re6S8(OH)6]4-
Kubeil, M.; Stephan, H.; Pietzsch, H.-J.; Geipel, G.; Appelhans, D.; Voit, B.; Hoffmann, J.; Brutschy, B.; Mironov, Y. V.; Brylev, K. A.; Fedorov, V. E.
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Chemistry - An Asian Journal 5(2010), 2507-2514
DOI: 10.1002/asia.201000284
Cited 32 times in Scopus
Comparison of the stability of Y-90-, Lu-177- and Ga-68- labeled human serum albumin microspheres (DOTA-HSAM)
Wunderlich, G.; Schiller, E.; Bergmann, R.; Pietzsch, H.-J.
Involved research facilities
- PET-Center
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Nuclear Medicine and Biology 37(2010), 861-867
DOI: 10.1016/j.nucmedbio.2010.05.004
Cited 30 times in Scopus
The traceless Staudinger ligation with fluorine-18: a novel and versatile labeling technique for the synthesis of PET-radiotracers
Pretze, M.; Wuest, F.; Peppel, T.; Köckerling, M.; Mamat, C.
Involved research facilities
- PET-Center
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Tetrahedron Letters 51(2010), 6410-6414
DOI: 10.1016/j.tetlet.2010.09.134
Cited 43 times in Scopus
Preparation, 99mTc-labeling and biodistribution studies of a PNA oligomer containing a new ligand derivative of 2,2′-dipicolylamine
Gasser, G.; Jäger, K.; Zenker, M.; Bergmann, R.; Steinbach, J.; Stephan, H.; Metzler-Nolte, N.
Involved research facilities
- PET-Center
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Journal of Inorganic Biochemistry 104(2010), 1133-1140
DOI: 10.1016/j.jinorgbio.2010.06.011
Cited 41 times in Scopus
Accessible silanol sites - beneficial for the RP-HPLC separation of constitutional and diastereomeric azaspirovesamicol isomers
Wenzel, B.; Fischer, S.; Brust, P.; Steinbach, J.
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Journal of Chromatography A 1217(2010), 7884-7890
DOI: 10.1016/j.chroma.2010.10.061
Cited 9 times in Scopus
A novel Dibenzoazacyclooctyne precursor in regioselective Copper-free click chemistry. An innovative 3-step synthesis.
Starke, F.; Walther, M.; Pietzsch, H.-J.
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ARKIVOC (2010), 350-359
ISSN: 1551-7012
Synthesis and Radiofluorination of Iodophenyl Esters as Tool for the Traceless Staudinger Ligation
Pretze, M.; Flemming, A.; Köckerling, M.; Mamat, C.
Involved research facilities
- PET-Center
- Zeitschrift für Naturforschung Section B - A Journal of Chemical Sciences 65(2010), 1128-1136
3D QSAR study, synthesis and in vitro evaluation of (+)-5-FBVM as potential PET radioligand for the Vesicular AcetylCholine Transporter (VAChT)
Kovac, M.; Mavel, S.; Deuther-Conrad, W.; Méheux, N.; Glöckner, J.; Wenzel, B.; Anderluh, M.; Brust, P.; Guilloteau, D.; Emond, P.
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Bioorganic & Medicinal Chemistry 18(2010), 7659-7667
DOI: 10.1016/j.bmc.2010.08.028
Cited 24 times in Scopus
A new hexanuclear rhenium cluster complex with six terminal acetate ligands: Synthesis, structure, and properties of K4[Re6S8(CH3COO)6]·8H2O
Brylev, K. A.; Mironov, Y. V.; Fedorov, V. E.; Kim, S.-J.; Pietzsch, H.-J.; Stephan, H.; Ito, A.; Kitamura, N.
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Inorganica Chimica Acta 363(2010)11, 2686-2691
DOI: 10.1016/j.ica.2010.04.042
Cited 36 times in Scopus
Novel 99mTc '4 + 1' peptide conjugates: Tuning the biodistribution by variation of coligands
Künstler, J.-U.; Seidel, G.; Bergmann, R.; Gniazdowska, E.; Walther, M.; Schiller, E.; Decristoforo, C.; Stephan, H.; Haubner, R.; Steinbach, J.; Pietzsch, H.-J.
Involved research facilities
- PET-Center
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European Journal of Medicinal Chemistry 45(2010), 3645-3655
DOI: 10.1016/j.ejmech.2010.05.010
Cited 17 times in Scopus
Eph Receptors and Ephrin Ligands: Important Players in Angiogenesis and Tumor Angiogenesis
Mosch, B.; Reissenweber, B.; Neuber, C.; Pietzsch, J.
Involved research facilities
- PET-Center
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Journal of Oncology 2010(2010), 135285
DOI: 10.1155/2010/135285
Cited 104 times in Scopus
Cyclin-Dependent Kinase 4/6 (Cdk4/6) Inhibitors: Perspectives in Cancer Therapy and Imaging
Graf, F.; Mosch, B.; Koehler, L.; Bergmann, R.; Wuest, F.; Pietzsch, J.
Involved research facilities
- PET-Center
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Mini-Reviews in Medicinal Chemistry 10(2010), 527-539
ISSN: 1389-5575
Synthesis and biological evaluation of a radioiodinated spiropiperidine ligand as a potential σ1 receptor imaging agent
Chen, R.-Q.; Li, Y.; Zhang, Q.-Y.; Jia, H.-M.; Deuther-Conrad, W.; Schepmann, D.; Steinbach, J.; Brust, P.; Wuensch, B.; Liu, B.-L.
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Journal of Labelled Compounds and Radiopharmaceuticals 53(2010), 569-574
DOI: 10.1002/jlcr.1777
Cited 11 times in Scopus
Design, Synthesis and in Vitro Biological Evaluation of Reference Compounds of 123I and 99Tcm Labeled Indole Radiotracers for σ2 Receptor Imaging
Li, Y.; Jia, H.-M.; Deuther-Conrad, W.; Brust, P.; Steinbach, J.; Liu, B.-L.
- Journal of Nuclear and Radiochemistry 32(2010)2, 132-138
Synthesis of neurotensin(8-13)-phosphopeptide heterodimers via click chemistry
Richter, S.; Ramenda, T.; Bergmann, R.; Knieß, T.; Steinbach, J.; Pietzsch, J.; Wuest, F.
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Bioorganic & Medicinal Chemistry Letters 20(2010), 3306-3309
DOI: 10.1016/j.bmcl.2010.04.038
ISSN: 0960-894X
Cited 8 times in Scopus
Effects of lateral fluid percussion injury on cholinergic markers in the newborn piglet brain
Donat, C. K.; Walter, B.; Kayser, T.; Deuther-Conrad, W.; Schliebs, R.; Nieber, K.; Bauer, R.; Haertig, W.; Brust, P.
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International Journal of Developmental Neuroscience 28(2010), 31-38
DOI: 10.1016/j.ijdevneu.2009.10.001
Cited 12 times in Scopus
Alterations of cholinergic receptors and the vesicular acetylcholine transporter after lateral fluid percussion injury in newborn piglets
Donat, C. K.; Walter, B.; Deuther-Conrad, W.; Nieber, K.; Brust, R.; Bauer, P.
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Neuropathology and Applied Neurobiology 36(2010), 225-236
DOI: 10.1111/j.1365-2990.2009.01050.x
Cited 13 times in Scopus
Novel Indole Derivatives as Potential Imaging Agents for Alzheimers Disease
Yu, L.; Scheunemann, M.; Deuther-Conrad, W.; Hiller, A.; Fischer, S.; Sorger, D.; Sabri, O.; Jia, H.; Steinbach, J.; Brust, P.; Liu, B.
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Bulletin of the Korean Chemical Society 31(2010)1, 177-180
DOI: 10.5012/bkcs.2010.31.01.177
Cited 1 times in Scopus
Crystal structure of N-benzyl-4-fluorobenzamide, C14H12FNO, at 173 K
Mamat, C.; Flemming, A.; Köckerling, M.
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Zeitschrift für Kristallographie - New Crystal Structures 225(2010), 345-346
DOI: 10.1524/ncrs.2010.0150
Cited 1 times in Scopus
Iodine-124: A Promising Positron Emitter for Organic PET Chemistry
Koehler, L.; Gagnon, K.; Mcquarrie, S.; Wuest, F.
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Molecules 15(2010), 2686-2718
DOI: 10.3390/molecules15042686
ISSN: 1420-3049
Cited 92 times in Scopus
Efficient preparation of 99mTc(III) 4+1 mixed-ligand complexes for peptide labeling with high specific activity
Künstler, J.-U.; Seidel, G.; Pietzsch, H.-J.
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Applied Radiation and Isotopes 68(2010), 1728-1733
DOI: 10.1016/j.apradiso.2010.04.008
Cited 8 times in Scopus
Enantioseparation of vesamicol and novel vesamicol analogs by high-performance liquid chromatography on different chiral stationary phases
Wenzel, B.; Fischer, S.; Brust, P.; Steinbach, J.
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Journal of Chromatography A 1217(2010), 3855-3862
DOI: 10.1016/j.chroma.2010.04.018
Cited 15 times in Scopus
Radiosynthesis and radiopharmacological evaluation of cyclin-dependent kinase 4 (Cdk4) inhibitors
Koehler, L.; Graf, F.; Bergmann, R.; Steinbach, J.; Pietzsch, J.; Wuest, F.
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European Journal of Medicinal Chemistry 45(2010), 727-737
DOI: 10.1016/j.ejmech.2009.11.020
Cited 20 times in Scopus
Scavenger receptors are associated with cellular interactions of S100A12 in vitro and in vivo
Hoppmann, S.; Steinbach, J.; Pietzsch, J.
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International Journal of Biochemistry & Cell Biology 42(2010), 651-661
DOI: 10.1016/j.biocel.2009.12.010
Cited 26 times in Scopus
Effects of posture on regional pulmonary blood flow in rats as measured by PET
Richter, T.; Bergmann, R.; Pietzsch, J.; Közle, I.; Hofheinz, F.; Schiller, E.; Ragaller, M.; van den Hoff, J.
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Journal of Applied Physiology 108(2010), 422-429
DOI: 10.1152/japplphysiol.91257.2008
Cited 21 times in Scopus
Comment on "Developing DCE-CT to Quantify Intra-Tumor Heterogeneity in Breast Tumors With Differing Angiogenic Phenotype"
Abramyuk, A.; Wolf, G.; Hietschold, V.; Haberland, U.; van den Hoff, J.; Abolmaali, N.
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IEEE Transactions on Medical Imaging 29(2010)4, 1088-1092
DOI: 10.1109/TMI.2009.2031780
Cited 1 times in Scopus
Effects of cold sphere walls in PET phantom measurements on the volume reproducing threshold
Hofheinz, F.; Dittrich, S.; Pötzsch, C.; van den Hoff, J.
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Physics in Medicine and Biology 55(2010), 1099-1113
DOI: 10.1088/0031-9155/55/4/013
Cited 86 times in Scopus
Improved Multimodality Imaging Using Alginate Molding in Xenograft Tumor Models
Strobel, K.; Bergmann, R.; Meister, S.; van den Hoff, J.; Pietzsch, J.
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Journal of Magnetic Resonance Imaging 31(2010), 747-752
DOI: 10.1002/jmri.22090
Cited 5 times in Scopus
2009
Recent Application of Click Chemistry for the Synthesis of Radiotracers for Molecular Imaging
Mamat, C.; Ramenda, T.; Wuest, F.
- Mini-Reviews in Organic Chemistry 6(2009), 21-34
Fluorine-18 labeling of phosphopeptides: a potential approach for the evaluation of phosphopeptide metabolism in vivo.
Richter, S.; Bergmann, R.; Pietzsch, J.; Ramenda, T.; Steinbach, J.; Wuest, F.
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Biopolymers 92(2009)6, 479-488
DOI: 10.1002/bip.21263
Cited 14 times in Scopus
PET-based investigation of cerebral activation following intranasal trigeminal stimulation
Hummel, T.; Oehme, L.; van den Hoff, J.; Gerber, J.; Heinke, M.; Boyle, J. A.; Beuthien-Baumann, B.
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Human Brain Mapping 30(2009), 1100-1104
DOI: 10.1002/hbm.20573
Cited 27 times in Scopus
Analysis of non-protein amino acids as specific markers of protein oxidation: the use of N(O,S)-ethoxycarbonyl ethyl ester and N(O,S)-ethoxycarbonyl trifluoroethyl ester derivatives and GC-MS
Pietzsch, J.; Pietzsch, F.-J.; Kopprasch, S.
- Trends in Chromatography 5(2009), 15-20
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