Publications of Institute of Radiopharmaceutical Cancer Research
1324 Publications2015
Spatial distribution of FMISO in head and neck squamous cell carcinomas during radio-chemotherapy and its correlation to pattern of failure
Zschaeck, S.; Haase, R.; Abolmaali, N.; Perrin, R.; Stützer, K.; Appold, S.; Steinbach, J.; Kotzerke, J.; Zips, D.; Richter, C.; Gudziol, V.; Krause, M.; Zöphel, K.; Baumann, M.
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Acta Oncologica 54(2015), 1355-1363
DOI: 10.3109/0284186X.2015.1074720
ISSN: 0284-186X
Prognostic Value of Pretherapeutic Tumor-to-Blood Standardized Uptake Ratio in Patients with Esophageal Carcinoma
Bütof, R.; Hofheinz, F.; Zöphel, K.; Stadelmann, T.; Schmollack, J.; Jentsch, C.; Loeck, S.; Kotzerke, J.; Baumann, M.; van den Hoff, J.
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Journal of Nuclear Medicine 56(2015), 1150-1156
DOI: 10.2967/jnumed.115.155309
ISSN: 0161-5505
Correction of quantification errors in pelvic and spinal lesions caused by ignoring higher photon attenuation of bone in [18F]NaF PET/MR
Schramm, G.; Maus, J.; Hofheinz, F.; Petr, J.; Lougovski, A.; Beuthien-Baumann, B.; Oehme, L.; Platzek, I.; van den Hoff, J.
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Medical Physics 42(2015), 6468-6476
DOI: 10.1118/1.4932367
Evaluation of in vivo quantification accuracy of the Ingenuity-TF PET/MR
Maus, J.; Schramm, G.; Hofheinz, F.; Oehme, L.; Lougovski, A.; Petr, J.; Platzek, I.; Beuthien-Baumann, B.; Steinbach, J.; Kotzerke, J.; van den Hoff, J.
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Medical Physics 42(2015)10, 5773-5781
DOI: 10.1118/1.4929936
Bispecific antibody releasing-mesenchymal stromal cell machinery for retargeting T cells towards acute myeloid leukemia blasts
Aliperta, R.; Cartellieri, M.; Feldmann, A.; Arndt, C.; Koristka, S.; Michalk, I.; von Bonin, M.; Ehninger, A.; Bachmann, J.; Ehninger, G.; Bornhäuser, M.; Bachmann, M. P.
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Blood Cancer Journal 5(2015), e348
DOI: 10.1038/bcj.2015.73
18F-Labeled 1,4-Dioxa-8-azaspiro[4.5]decane Derivative: Synthesis and Biological Evaluation of a σ1 Receptor Radioligand with Low Lipophilicity as Potent Tumor Imaging Agent
Xie, F.; Bergmann, R.; Kniess, T.; Deuther-Conrad, W.; Mamat, C.; Neuber, C.; Liu, B.; Steinbach, J.; Brust, P.; Pietzsch, J.; Jia, H.
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Journal of Medicinal Chemistry 58(2015), 5395-5407
DOI: 10.1021/acs.jmedchem.5b00593
ISSN: 0022-2623
Targeting lysyl oxidase for molecular imaging in breast cancer
Wuest, M.; Kuchar, M.; Sharma, S. K.; Richter, S.; Hamann, I.; Wang, M.; Vos, L.; Mackey, J. R.; Wuest, F.; Löser, R.
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Breast Cancer Research 17(2015), 107
DOI: 10.1186/s13058-015-0609-9
18F-FDG PET/MRI for therapy response assessment in sarcoma: Comparison of PET and MR imaging results
Schuler, M. K.; Platzek, I.; Beuthien-Baumann, B.; Fenchel, M.; Ehninger, G. E.; van den Hoff, J.
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Clinical Imaging 39(2015), 866-870
DOI: 10.1016/j.clinimag.2015.05.014
2-[18F]Fluoroethyl tosylate - a versatile tool for building 18F-based radiotracers for positron emission tomography
Knieß, T.; Laube, M.; Brust, P.; Steinbach, J.
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MedChemComm 6(2015), 1714-1754
DOI: 10.1039/c5md00303b
Repeatability of tumor SUV quantification: the role of variable blood SUV
van den Hoff, J.; Hofheinz, F.
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Journal of Nuclear Medicine 56(2015)10, 1635-1636
DOI: 10.2967/jnumed.115.161570
Novel (pyrazolyl)benzenesulfonamides with a nitric oxide-releasing moiety as selective cyclooxygenase-2 inhibitors
Bechmann, N.; Kniess, T.; Köckerling, M.; Pigorsch, A.; Steinbach, J.; Pietzsch, J.
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Bioorganic & Medicinal Chemistry Letters 25(2015), 3295-3300
DOI: 10.1016/j.bmcl.2015.05.059
Rational design of dual peptides targeting ghrelin and Y2 receptors to regulate food intake and body weight
Kilian, T. M.; Klöting, N.; Bergmann, R.; Els-Heindl, S.; Babilon, S.; Clément-Ziza, M.; Zhang, Y.; Beck-Sickinger, A. G.; Chollet, C.
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Journal of Medicinal Chemistry 58(2015), 4180-4193
DOI: 10.1021/jm501702q
ISSN: 0022-2623
On the relation between Kaiser-Bessel blob and tube of response based modelling of the system matrix in iterative PET image reconstruction
Lougovski, A.; Hofheinz, F.; Maus, J.; Schramm, G.; van den Hoff, J.
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Physics in Medicine and Biology 60(2015), 4209-4224
DOI: 10.1088/0031-9155/60/10/4209
ISSN: 0031-9155
Methods to increase the metabolic stability of 18F-radiotracers
Kuchar, M.; Mamat, C.
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Molecules 20(2015), 16186-16220
DOI: 10.3390/molecules200916186
In vivo Demonstration of an Active Tumor Pretargeting Approach with Peptide Nucleic Acid Bioconjugates as Complementary System
Leonidova, A.; Foerster, C.; Zarschler, K.; Schubert, M.; Pietzsch, H.-J.; Steinbach, J.; Bergmann, R.; Metzler-Nolte, N.; Stephan, H.; Gasser, G.
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Chemical Science 6(2015), 5601-5616
DOI: 10.1039/c5sc00951k
Synthesis and First Evaluation of [18F]Fluorocyano- and [18F]Fluoronitroquinoxalinedione as Putative AMPA Receptor Antagonists
Olma, S.; Ermert, J.; Sihver, W.; Coenen, H.-H.
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Medicinal Chemistry 11(2015)1, 13-20
DOI: 10.2174/1573406410666140428151318
ISSN: 1875-6638
Biodistribution, cellular localization, and in vivo tolerability of S-35-labeled antiinflammatory dendritic polyglycerol sulfate amine
Holzhausen, C.; Groger, D.; Mundhenk, L.; Donat, C. K.; Schnorr, J.; Haag, R.; Gruber, A. D.
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Journal of Nanoparticle Research 17(2015)3, 115-127
DOI: 10.1007/s11051-015-2927-3
ISSN: 1388-0764
Active Site Mapping of Human Cathepsin F with Dipeptide Nitrile Inhibitors
Schmitz, J.; Furtmann, N.; Ponert, M.; Frizler, M.; Löser, R.; Bartz, U.; Bajorath, J.; Gütschow, M.
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ChemMedChem 10(2015)8, 1365-1377
DOI: 10.1002/cmdc.201500151
Cysteine cathepsins: their role in tumor progression and recent trends in the development of imaging probes
Löser, R.; Pietzsch, J.
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Frontiers in Chemistry 3(2015), 37
DOI: 10.3389/fchem.2015.00037
Copper(II) cyclam complexes with N-propionic acid pendant arms
Kubeil, M.; Zarschler, K.; Pietzsch, J.; Kraus, W.; Comba, P.; Stephan, H.
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European Journal of Inorganic Chemistry 2015(2015), 4013-4023
DOI: 10.1002/ejic.201500510
Novel indole-based sigma-2 receptor ligands: synthesis, structure–affinity relationship and antiproliferative activity
Xie, F.; Kniess, T.; Neuber, C.; Deuther-Conrad, W.; Mamat, C.; Liebermann, B. P.; Liu, B.; Mach, R. H.; Brust, P.; Steinbach, J.; Pietzsch, J.; Jia, H.
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MedChemComm 6(2015), 1093-1103
DOI: 10.1039/c5md00079c
First-in-human PET quantification study of cerebral α4β2* nicotinic acetylcholine receptors using the novel specific radioligand (−)-[18F]Flubatine
Sabri, O.; Becker, G.-A.; Meyer, P. M.; Hesse, S.; Wilke, S.; Graef, S.; Patt, M.; Luthardt, J.; Wagenknecht, G.; Hoepping, A.; Smits, R.; Franke, A.; Sattler, B.; Habermann, B.; Neuhaus, P.; Fischer, S.; Tiepolt, S.; Deuther-Conrad, W.; Barthel, H.; Schönknecht, P.; Brust, P.
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NeuroImage 118(2015), 199-208
DOI: 10.1016/j.neuroimage.2015.05.065
Combined PET/MR: The Real Work Has Just Started. Summary Report of the Third International Workshop on PET/MR Imaging; February 17-21, 2014, Tubingen, Germany
Bailey, D. L.; Antoch, G.; Bartenstein, P.; Barthel, H.; Beer, A. J.; Bisdas, S.; Bluemke, D. A.; Boellaard, R.; Claussen, C. D.; Franzius, C.; Hacker, M.; Hricak, H.; La Fougere, C.; Guckel, B.; Nekolla, S. G.; Pichler, B. J.; Purz, S.; Quick, H. H.; Sabri, O.; Sattler, B.; Schafer, J.; Schmidt, H.; van den Hoff, J.; Voss, S.; Weber, W.; Wehrl, H. F.; Beyer, T.
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Molecular Imaging and Biology 17(2015), 297-312
DOI: 10.1007/s11307-014-0818-0
ISSN: 1536-1632
The association of tumor-to-background ratios and SUVmax deviations related to point spread function and time-of-flight F18-FDG-PET/CT reconstruction in colorectal liver metastases
Rogasch, J. M. M.; Steffen, I. G.; Hofheinz, F.; Großer, O. S.; Furth, C.; Mohnike, K.; Hass, P.; Walke, M.; Apostolova, I.; Amthauer, H.
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EJNMMI Research 5(2015), 1-9
DOI: 10.1186/s13550-015-0111-5
ISSN: 2191-219X
Synthesis and Molecular Structure of 2-(Diphenylphosphano) phenyl Benzoate Borane Adduct
Mamat, C.; Köckerling, M.
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Crystals 5(2015), 9-13
DOI: 10.3390/cryst5010009
ISSN: 2073-4352
DAP12-Based Activating Chimeric Antigen Receptor for NK Cell Tumor Immunotherapy
Toepfer, K.; Cartellieri, M.; Michen, S.; Wiedemuth, R.; Mueller, N.; Lindemann, D.; Bachmann, M.; Fuessel, M.; Schackert, G.; Temme, A.
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Journal of Immunology 194(2015), 3201-3212
DOI: 10.4049/jimmunol.1400330
ISSN: 0022-1767
A promising PET tracer for imaging of α7 nicotinic acetylcholine receptors in the brain: Design, synthesis, and in vivo evaluation of a dibenzothiophene-based radioligand
Teodoro, R.; Scheunemann, M.; Deuther-Conrad, W.; Wenzel, B.; Colombo, S.; Gotti, C.; Kranz, M.; Donat, C.; Patt, M.; Hillmer, A.; Zheng, M.; Peters, D.; Steinbach, J.; Sabri, O.; Huang, Y.; Brust, P.
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Molecules 20(2015), 18387-18421
DOI: 10.3390/molecules201018387
ISSN: 1420-3049
CuII-selective bispidine–dye conjugates
Bronx, D.; Comba, P.; Herten, D.-P.; Kimmle, E.; Morgen, M.; Rühl, C. L.; Rybina, A.; Stephan, H.; Storch, G.; Wadepohl, H.
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Journal of Inorganic Biochemistry 148(2015), 78-83
DOI: 10.1016/j.jinorgbio.2015.05.009
Improving external beam radiotherapy by combination with internal irradiation.
Dietrich, A.; Koi, L.; Zöphel, K.; Sihver, W.; Kotzerke, J.; Baumann, M.; Krause, M.
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British Journal of Radiology 17(2015), 20150042
DOI: 10.1259/bjr.20150042
Synthesis and Biodistribution Studies of 3H- and 64Cu-labeled Dendritic Polyglycerol and Dendritic Polyglycerol Sulfate
Pant, K.; Gröger, D.; Bergmann, R.; Pietzsch, J.; Steinbach, J.; Graham, B.; Spiccia, L.; Berthon, F.; Czarny, B.; Devel, L.; Dive, V.; Stephan, H.; Haag, R.
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Bioconjugate Chemistry 26(2015), 906-918
DOI: 10.1021/acs.bioconjchem.5b00127
Synthesis, 18F-radiolabelling and biological characterization of novel fluoroalkylated triazine derivatives for in vivo imaging of phosphodiesterase 2A in brain via positron emission tomography
Schröder, S.; Wenzel, B.; Deuther-Conrad, W.; Teodoro, R.; Egerland, U.; Kranz, M.; Scheunemann, M.; Höfgen, N.; Steinbach, J.; Brust, P.
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Molecules 20(2015), 9591-9615
DOI: 10.3390/molecules20069591
ISSN: 1420-3049
Development of indazolylpyrimidine derivatives as high-affine EphB4 receptor ligands and potential PET-radiotracers
Ebert, K.; Wiemer, J.; Caballero, J.; Köckerling, M.; Steinbach, J.; Pietzsch, J.; Mamat, C.
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Bioorganic & Medicinal Chemistry 23(2015), 6025-6035
DOI: 10.1016/j.bmc.2015.06.040
Reduced pulmonary blood flow in regions of injury 2 hours after acid aspiration in rats
Richter, T.; Bergmann, R.; Musch, G.; Pietzsch, G.; Koch, T.
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BMC Anesthesiology 15(2015), 36
DOI: 10.1186/s12871-015-0013-0
Accuracy of parenchymal cerebral blood flow measurements using pseudo-continuous arterial spin labeling in healthy volunteers
Ambarki, K.; Wåhlin, A.; Zarrinkoob, L.; Wirestam, R.; Petr, J.; Malm, J.; Eklund, A.
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American Journal of Neuroradiology 36(2015), 1816-1821
DOI: 10.3174/ajnr.A4367
Tregs activated by bispecific antibodies: Killers or suppressors?
Koristka, S.; Cartellieri, M.; Arndt, C.; Feldmann, A.; Seliger, B.; Ehninger, G.; Bachmann, M. P.
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OncoImmunology 4(2015)3, e994441
DOI: 10.4161/2162402X.2014.994441
Optical imaging of COX-2: Studies on an autofluorescent 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitor.
Tondera, C.; Ullm, S.; Laube, M.; Meister, S.; Neuber, C.; Mosch, B.; Kniess, T.; Pietzsch, J.
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Biochemical and Biophysical Research Communications 458(2015), 40-45
DOI: 10.1016/j.bbrc.2015.01.057
Theranostic mercury: 197(m)Hg with high specific activity for imaging and therapy
Walther, M.; Preusche, S.; Bartel, S.; Wunderlich, G.; Freudenberg, R.; Steinbach, J.; Pietzsch, H.-J.
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Applied Radiation and Isotopes 97(2015), 177-181
DOI: 10.1016/j.apradiso.2015.01.001
New systematically modified vesamicol analogs and their affinity and selectivity for the vesicular acetylcholine transporter – A critical examination of the lead structure.
Barthel, C.; Sorger, D.; Deuther-Conrad, W.; Scheunemann, M.; Schweiger, S.; Jäckel, P.; Roghani, A.; Steinbach, J.; Schüürmann, G.; Sabri, O.; Brust, P.; Wenzel, B.
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European Journal of Medicinal Chemistry 100(2015), 50-67
DOI: 10.1016/j.ejmech.2015.05.033
Cyclopeptides containing the DEKS motif as conformationally restricted collagen telopeptide analogues: synthesis and conformational analysis
Wodtke, R.; Ruiz-Gómez, G.; Kuchar, M.; Pisabarro, M. T.; Novotná, P.; Urbanová, M.; Steinbach, J.; Pietzsch, J.; Löser, R.
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Organic & Biomolecular Chemistry 13(2015), 1878-1896
DOI: 10.1039/C4OB02348J
Speciation of uranium in compartments of living cells
Geipel, G.; Viehweger, K.
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BioMetals 28(2015)3, 529-539
DOI: 10.1007/s10534-015-9836-x
Bifunctional Cyclam-Based Ligands with Phosphorus Acid Pendant Moieties for Radiocopper Separation – Thermodynamic and Kinetic Studies
Paúrová, M.; Havlíčková, J.; Pospíšilová, A.; Vetrík, M.; Císařová, I.; Stephan, H.; Pietzsch, H.-J.; Hrubý, M.; Hermann, P.; Kotek, J.
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Chemistry - A European Journal 21(2015), 4671-4687
DOI: 10.1002/chem.201405777
Diaryl-substituted (dihydro)pyrrolo[3,2,1-hi]indoles, a class of potent COX-2 inhibitors with tricyclic core structure
Laube, M.; Gassner, C.; Sharma, S. K.; Günther, R.; Pigorsch, A.; König, J.; Köckerling, M.; Wuest, F.; Pietzsch, J.; Kniess, T.
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Journal of Organic Chemistry 80(2015), 5611-5624
DOI: 10.1021/acs.joc.5b00537
Polyoxometalates - potent and selective ecto-nucleotidase inhibitors
Lee, S.-Y.; Fiene, A.; Li, W.; Hank, T.; Brylev, K.; Fedovrov, V.; Lecka, J.; Haider, A.; Pietzsch, H.-J.; Zimmermann, H.; Sévigny, J.; Kortz, U.; Stephan, H.; Müller, C. E.
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Biochemical Pharmacology 93(2015), 171-181
DOI: 10.1016/j.bcp.2014.11.002
A high-yield automated radiosynthesis of the alpha-7 nicotinic receptor radioligand [18F]NS10743
Teodoro, R.; Wenzel, B.; Oh-Nishi, A.; Fischer, S.; Peters, D.; Suhara, T.; Deuther-Conrad, W.; Brust, P.
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Applied Radiation and Isotopes 95(2015), 76-84
DOI: 10.1016/j.apradiso.2014.09.016
Effects of pulmonary acid aspiration on the regional pulmonary blood flow within the first hour after injury: an observational study in rats
Richter, T.; Bergmann, R.; Pietzsch, J.; Mueller, M. P.; Koch, T.
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Clinical Hemorheology and Microcirculation 60(2015), 253-262
Online First (2014) DOI: 10.3233/CH-141867
Convenient recycling and reuse of bombarded [18O]H2O for the production and the application of [18F]F‒
Rötering, S.; Franke, K.; Zessin, J.; Brust, P.; Füchtner, F.; Fischer, S.; Steinbach, J.
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Applied Radiation and Isotopes 101(2015), 44-52
DOI: 10.1016/j.apradiso.2015.03.009
Evaluation of Novel Fluorescence Probes for Conjugation Purposes Using the Traceless Staudinger Ligation
Wodtke, R.; König, J.; Pigorsch, A.; Köckerling, M.; Mamat, C.
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Dyes and Pigments 113(2015), 263-273
Online First (2014) DOI: 10.1016/j.dyepig.2014.08.022
2014
Quantitative assessment of the asphericity of pretherapeutic FDG uptake as an independent predictor of outcome in NSCLC.
Apostolova, I.; Rogasch, J.; Buchert, R.; Wertzel, H.; Achenbach, H. J.; Schreiber, J.; Riedel, S.; Furth, C.; Lougovski, A.; Schramm, G.; Hofheinz, F.; Amthauer, H.; Steffen, I. G.
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BMC Cancer 14(2014), 896
DOI: 10.1186/1471-2407-14-896
The influence of different signal-to-background ratios on spatial resolution and F18-FDG-PET quantification using point spread function and time-of-flight reconstruction
Rogasch, J. M. M.; Hofheinz, F.; Lougovski, A.; Furth, C.; Ruf, J.; Großer, O. S.; Mohnike, K.; Hass, P.; Walke, M.; Amthauer, H.; Steffen, I. G.
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EJNMMI Physics 1(2014)
DOI: 10.1186/2197-7364-1-12
Dual Role of B7 Costimulation in Obesity-Related Nonalcoholic Steatohepatitis and Metabolic Dysregulation
Chatzigeorgiou, A.; Chung, K.-J.; Garcia-Martin, R.; Alexaki, V.-I.; Klotzsche-Von Ameln, A.; Phieler, J.; Sprott, D.; Kanczkowski, W.; Tzanavari, T.; Bdeir, M.; Bergmann, S.; Cartellieri, M.; Bachmann, M.; Nikolakopoulou, P.; Androutsellis-Theotokis, A.; Siegert, G.; Bornstein, S. R.; Muders, M. H.; Boon, L.; Karalis, K. P.; Lutgens, E.; Chavakis, T.
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Hepatology 60(2014), 1196-1210
DOI: 10.1002/hep.27233
ISSN: 0270-9139
FDG PET/MR for the Assessment of Lymph Node Involvement in Lymphoma: Initial Results and Role of Diffusion-Weighted MR
Platzek, I.; Beuthien-Baumann, B.; Ordemann, R.; Maus, J.; Schramm, G.; Kitzler, H. H.; Laniado, M.; Kotzerke, J.; van den Hoff, J.
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Academic Radiology 21(2014)10, 1314-1319
DOI: 10.1016/j.acra.2014.05.019
ISSN: 1076-6332
Preparation of 4-Halobenzoate Containing Phosphane Based Building Blocks for Labeling Reactions Using the Traceless Staudinger Ligation
Mamat, C.; Köckerling, M.
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Synthesis 46(2014)2, 387-394
DOI: 10.1055/s-0034-1379487
X-ray structure of 2-(diphenylphosphano)phenyl-4-(hydroxymethyl)benzoate
Mamat, C.; Flemming, A.; Köckerling, M.
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Acta Crystallographica Section E E70(2014), o1288-o1289
DOI: 10.1107/S1600536814024623
ISSN: 1600-5368
Organotypical vascular model for characterization of radioprotective compounds: Studies on antioxidant 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitors
Ullm, S.; Laube, M.; Bechmann, N.; Knieß, T.; Pietzsch, J.
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Clinical Hemorheology and Microcirculation 58(2014), 281-295
DOI: 10.3233/CH-141902
Internal Dose Assessment of (-)-18F-Flubatine, Comparing Animal Model Datasets of Mice and Piglets with First-in-Human Results
Sattler, B.; Kranz, M.; Starke, A.; Wilke, S.; Donat, C. K.; Deuther-Conrad, W.; Patt, M.; Schildan, A.; Patt, J.; Smits, R.; Hoepping, A.; Schoenknecht, P.; Steinbach, J.; Brust, P.; Sabri, O.
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Journal of Nuclear Medicine 55(2014)11, 1885-1892
DOI: 10.2967/jnumed.114.137059
ISSN: 2159-662X
Redirection of CD4+ and CD8+ T lymphocytes via a novel antibody-based modular targeting system triggers efficient killing of PSCA+ prostate tumor cells
Arndt, C.; Feldmann, A.; Töpfer, K.; Koristka, S.; Cartellieri, M.; Temme, A.; Ehninger, A.; Ehninger, G.; Bachmann, M.
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The Prostate 74(2014), 1347-1358
DOI: 10.1002/pros.22851
Synthesis and evaluation of a 18F-labeled spirocyclic piperidine derivative as promising σ1 receptor imaging agent
Chen, Y.-Y.; Wang, X.; Zhang, J.-M.; Deuther-Conrad, W.; Zhang, X.-J.; Huang, Y.; Li, Y.; Ye, J.-J.; Cui, M.-C.; Steinbach, J.; Brust, P.; Liu, B.-L.
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Bioorganic & Medicinal Chemistry 22(2014), 5270-5278
DOI: 10.1016/j.bmc.2014.08.003
Novel Cyclopentadienyl Tricarbonyl 99mTc Complexes Containing 1‑Piperonylpiperazine Moiety: Potential Imaging Probes for Sigma‑1 Receptors
Wang, X.; Li, D.; Deuther-Conrad, W.; Lu, J.; Xie, Y.; Jia, B.; Cui, M.; Steinbach, J.; Brust, P.; Liu, B.; Jia, H.
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Journal of Medicinal Chemistry 57(2014), 7113-7125
DOI: 10.1021/jm5009488
Characterization of circulating microparticle-associated CD39 family ecto-nucleotidases in human plasma
Jiang, Z. G.; Wu, Y.; Csizmadia, E.; Feldbrügge, L.; Enjyoji, K.; Tigges, J.; Toxavidis, V.; Stephan, H.; Müller, C. E.; Mcknight, C. J.; Moss, A.; Robson, S. C.
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Purinergic Signalling 10(2014), 611-618
DOI: 10.1007/s11302-014-9423-6
The Ti7-Containing, Tetrahedral 36-Tungsto-4-Arsenate(III)[Ti6(TiO6)(AsW9O33)4]20-
Wang, K.-Y.; Bassil, B. S.; Lin, Z. G.; Haider, A.; Cao, J.; Stephan, H.; Viehweger, K.; Kortz, U.
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Dalton Transactions 43(2014), 16143-16146
DOI: 10.1039/c4dt02494j
Bispidines for dual imaging
Stephan, H.; Walther, M.; Fähnemann, S.; Ceroni, P.; Molloy, J.; Bergamini, G.; Heisig, F.; Müller, C. E.; Kraus, W.; Comba, P.
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Chemistry - A European Journal 20(2014), 17011-17018
DOI: 10.1002/chem.201404086
2,3-Diaryl-substituted indole based COX-2 inhibitors as leads for imaging tracer development
Laube, M.; Tondera, C.; Sharma, S. K.; Bechmann, N.; Pietzsch, F.-J.; Pigorsch, A.; Köckerling, M.; Wuest, F.; Pietzsch, J.; Kniess, T.
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RSC Advances 4(2014), 38726-38742
DOI: 10.1039/c4ra05650g
In Vivo Fluorescence Imaging and Urinary Monoamines as Surrogate Biomarkers of Disease Progression in a Mouse Model of Pheochromocytoma
Ullrich, M.; Bergmann, R.; Peitzsch, M.; Cartellieri, M.; Quin, N.; Erhart-Bornstein, M.; Block, N. L.; Schalley, A. V.; Pietzsch, J.; Eisenhofer, G.; Bornstein, S. R.; Ziegler, C. G.
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Endocrinology 155(2014), 4149-4156
DOI: 10.1210/en.2014-1431
ISSN: 0013-7227
Biocompatibility and inflammatory response in vitro and in vivo to gelatin-based biomaterials with tailorable elastic properties
Ullm, S.; Krüger, A.; Tondera, C.; Gebauer, T. P.; Neffe, A. T.; Lendlein, A.; Jung, F.; Pietzsch, J.
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Biomaterials 35(2014), 9755-9766
DOI: 10.1016/j.biomaterials.2014.08.023
ISSN: 0142-9612
Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors
Gnad, T.; Scheibler, S.; von Kügelgen, I.; Scheele, C.; Kilic, A.; Glöde, A.; Hoffmann, L.; Reverte, L.; Horn, P.; Mutlu, S.; El-Tayeb, A.; Kranz, M.; Deuther-Conrad, W.; Brust, P.; Lidell, M.; Betz, M.; Enerbäck, S.; Schrader, J.; Yegutkin, G.; Mueller, C.; Pfeifer, A.
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Nature 516(2014), 395-399
DOI: 10.1038/nature13816
Asphericity of pretherapeutic tumour FDG uptake provides independent prognostic value in head-and-neck cancer
Apostolova, I.; Steffen, I. G.; Wedel, F.; Lougovski, A.; Marnitz, S.; Derlin, T.; Amthauer, H.; Buchert, R.; Hofheinz, F.; Brenner, W.
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European Radiology 24(2014), 2077-2087
DOI: 10.1007/s00330-014-3269-8
Periacetabular bone metabolism following hip revision surgery. PET-based evaluation of allograft osteointegration.
Bernstein, P.; Beuthien-Baumann, B.; Kotzerke, J.; Hofheinz, F.; Zessin, J.; Stiehler, M.; Günther, K.-P.
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Nuklearmedizin 53(2014), 147-154
DOI: 10.3413/Nukmed-0607-13-06
ISSN: 0029-5566
Zwitterionic-Coated "Stealth" Nanoparticles for Biomedical Applications: Recent Advances in Countering Biomolecular Corona Formation and Uptake by the Mononuclear Phagocyte System
Pombo Garcia, K.; Zarschler, K.; Barbaro, L.; Barreto, J. A.; O'Malley, W.; Spiccia, L.; Stephan, H.; Graham, B.
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Small 10(2014), 2516-2529
DOI: 10.1002/smll.201303540
ISSN: 1613-6810
Evaluation of metabolism, plasma protein binding and other biological parameters after administration of (−)-[18 F]Flubatine in humans
Patt, M.; Becker, G. A.; Grossmann, U.; Habermann, B.; Schildan, A.; Wilke, S.; Deuther-Conrad, W.; Graefe, S.; Fischer, S.; Smits, R.; Wagenknecht, G.; Steinbach, J.; Gertze, H.-J.; Hesse, S.; Schönknecht, P.; Brust, P.; Sabri, O.
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Nuclear Medicine and Biology 41(2014), 489-494
DOI: 10.1016/j.nucmedbio.2014.03.018
Assessment of the best N3− donors in preparation of [M(N)(PNP)]-based (M = 99mTc-; 188Re) target-specific radiopharmaceuticals: Comparison among succinic dihydrazide (SDH), N-methyl-S-methyl dithiocarbazate (HDTCZ) and PEGylated N-methyl-S-methyl dithiocarbazate (HO2C-PEG600-DTCZ)
Carta, D.; Jentschel, C.; Thieme, S.; Salvarese, N.; Morellato, N.; Refosco, F.; Ruzza, P.; Bergmann, R.; Pietzsch, H.-J.; Bolzati, C.
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Nuclear Medicine and Biology 41(2014), 570-581
DOI: 10.1016/j.nucmedbio.2014.04.126
Imaging of α7 nicotinic acetylcholine receptors in brain and cerebral vasculature of juvenile pigs with [18F]NS14490
Rötering, S.; Deuther-Conrad, W.; Cumming, P.; Donat, C. K.; Scheunemann, M.; Fischer, S.; Xiong, G.; Steinbach, J.; Peters, D.; Sabri, O.; Bucerius, J.; Brust, P.
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EJNMMI Research 4(2014), 1-11
DOI: 10.1186/s13550-014-0043-5
Bispidine dioxotetraaza macrocycles: a new class of bispidines for 64Cu PET imaging
Comba, P.; Kubeil, M.; Pietzsch, J.; Rudolf, H.; Stephan, H.; Zarschler, K.
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Inorganic Chemistry 53(2014), 6698-6707
DOI: 10.1021/ic500476u
Radiofluorination and first radiopharmacological characterization of a SWLAY peptide-based ligand targeting EphA2
Pretze, M.; Mosch, B.; Bergmann, R.; Steinbach, J.; Pietzsch, J.; Mamat, C.
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Journal of Labelled Compounds and Radiopharmaceuticals 57(2014), 660-665
DOI: 10.1002/jlcr.3237
Proinflammatory human 6-sulfo LacNAc-positive dendritic cells accumulate in intestinal acute graft-versus-host disease
Sommer, U.; Larsson, B.; Tuve, S.; Wehner, R.; Zimmermann, N.; Kramer, M.; Kloß, A.; Günther, C.; Babatz, J.; Schmelz, R.; Brückner, S.; Schetelig, J.; Bornhäuser, M.; Schäkel, K.; Bachmann, M. P.; Aust, D.; Baretton, G.; Schmitz, M.
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Haematologica -The Hematology Journal 99(2014), e86-e89
DOI: 10.3324/haematol.2013.101071
ISSN: 1592-8721
Combined measurement of tumor perfusion and glucose metabolism for improved tumor characterization in advanced cervical carcinoma: A PET/CT pilot study using [15O]water and [18F]fluorodeoxyglucose
Apostolova, I.; Hofheinz, F.; Buchert, R.; Steffen, I. G.; Michel, R.; Rosner, C.; Prasad, V.; Köhler, C.; Derlin, T.; Brenner, W.; Marnitz, S.
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Strahlentherapie und Onkologie 190(2014), 575-581
DOI: 10.1007/s00066-014-0611-7
ISSN: 1439-099X
Effect of [18F]FMISO stratified dose-escalation on local control in FaDu hSCC in nude mice
Schütze, C.; Bergmann, R.; Brüchner, K.; Mosch, B.; Yaromira, A.; Zips, D.; Hessel, F.; Krause, M.; Thames, H.; Kotzerke, J.; Steinbach, J.; Baumann, M.; Beuthien-Baumann, B.
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Radiotherapy and Oncology 111(2014), 81-87
DOI: 10.1016/j.radonc.2014.02.005
ISSN: 1879-0887
Potential of a Cetuximab-based radioimmunotherapy combined with external irradiation manifests in a 3-D cell assay
Ingargiola, M.; Runge, R.; Heldt, J.-M.; Freudenberg, R.; Steinbach, J.; Cordes, N.; Baumann, M.; Kotzerke, J.; Brockhoff, G.; Kunz-Schughart, L. A.
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International Journal of Cancer 135(2014), 968-980
DOI: 10.1002/ijc.28735
ISSN: 1097-0215
Evaluation and automatic correction of metal-implant-induced artifacts in MR-based attenuation correction in whole-body PET/MR imaging
Schramm, G.; Maus, J.; Hofheinz, F.; Petr, J.; Lougovski, A.; Beuthien-Baumann, B.; Platzek, I.; van den Hoff, J.
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Physics in Medicine and Biology 59(2014), 2713-2726
DOI: 10.1088/0031-9155/59/11/2713
ISSN: 0031-9155
EGF receptor-targeting peptide conjugate incorporating a near-IR fluorescent dye and a novel 1,4,7-triazacyclononane-based 64Cu(II) chelator assembled via click chemistry
Viehweger, K.; Barbaro, L.; Pombo García, K.; Joshi, T.; Geipel, G.; Steinbach, J.; Stephan, H.; Spiccia, L.; Graham, B.
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Bioconjugate Chemistry 25(2014)5, 1011-1022
DOI: 10.1021/bc5001388
Diagnostic nanoparticle targeting of the EGF-receptor in complex biological conditions using single-domain antibodies
Zarschler, K.; Prapainop, K.; Mahon, E.; Rocks, L.; Bramini, M.; Kelly, P.; Stephan, H.; Dawson, K. A.
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Nanoscale 6(2014), 6046-6056
DOI: 10.1039/c4nr00595c
Early increase of cannabinoid receptor density after experimental traumatic brain injury in the newborn piglet
Donat, C. K.; Fischer, F.; Walter, B.; Deuther-Conrad, W.; Brodhun, M.; Bauer, R.; Brust, P.
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Acta Neurobiologiae Experimentalis 74(2014), 197-210
ISSN: 0365-0820
Cytotoxic properties of radionuclide-conjugated Cetuximab without and in combination with external irradiation in head and neck cancer cells in vitro
Eke, I.; Ingargiola, M.; Förster, C.; Kunz-Schughart, L.; Baumann, M.; Runge, R.; Freudenberg, R.; Kotzerke, J.; Heldt, J.; Pietzsch, H.; Steinbach, J.; Cordes, N.
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International Journal of Radiation Biology 90(2014)8, 678-686
DOI: 10.3109/09553002.2014.899446
FDG PET/MR for lymph node staging in head and neck cancer
Platzek, I.; Beuthien-Baumann, B.; Schneider, M.; Gudziol, V.; Kitzler, H. H.; Maus, J.; Schramm, G.; Popp, M.; Laniado, M.; Kotzerke, J.; van den Hoff, J.
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European Journal of Radiology 83(2014)7, 1163-1168
DOI: 10.1016/j.ejrad.2014.03.023
Distinctive In Vivo Kinetics of the New Sigma1 Receptor Ligands (R)-(+) and (S)-(-)- 18F-Fluspidine in Porcine Brain
Brust, P.; Deuther-Conrad, W.; Becker, G.; Patt, M.; Dont, C. K.; Stittsworth, S.; Fischer, S.; Hiller, A.; Wenzel, B.; Dukic-Stefanovic, S.; Hesse, S.; Steinbach, J.; Wünsch, B.; Lever, S. Z.; Sabri, O.
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Journal of Nuclear Medicine 55(2014)10, 1730-1736
DOI: 10.2967/jnumed.114.137562
ISSN: 0161-5505
Correction of scan time dependence of standard uptake values in oncological PET
van den Hoff, J.; Lougovski, A.; Schramm, G.; Maus, J.; Oehme, L.; Petr, J.; Beuthien-Baumann, B.; Kotzerke, J.; Hofheinz, F.
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EJNMMI Research 4(2014), 18
DOI: 10.1186/2191-219X-4-18
Combined PET/MR: Where Are We Now? Summary Report of the Second International Workshop on PET/MR Imaging April 8–12, 2013, Tubingen, Germany
Bailey, D. L.; Barthel, H.; Beuthien-Baumann, B.; Beyer, T.; Bisdas, S.; Boellaard, R.; Czernin, J.; Drzezga, A.; Ernemann, U.; Franzius, C.; Gückel, B.; Handgretinger, R.; Hartenbach, M.; Hellwig, D.; Nadel, H.; Nekolla, S. G.; Pfluger, T.; Pichler, B. J.; Quick, H. H.; Sabri, O.; Sattler, B.; Schäfer, J.; Schick, F.; Siegel, B. A.; Schlemmer, H. P.; Schwenzer, N. F.; van den Hoff, J.; Veit-Haibach, P.; Wehrl, H. F.
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Molecular Imaging and Biology 16(2014)3, 295-310
DOI: 10.1007/s11307-014-0725-4
ISSN: 1536-1632
Metastatic potential of B16-F10 melanoma cells is enhanced by extracellular S100A4 derived from RAW264.7 macrophages
Haase-Kohn, C.; Wolf, S.; Herwig, N.; Mosch, B.; Pietzsch, J.
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Biochemical and Biophysical Research Communications 446(2014), 143-148
DOI: 10.1016/j.bbrc.2014.02.126
Simultaneous Targeting of Prostate Stem Cell Antigen and Prostate-Specific Membrane Antigen Improves the Killing of Prostate Cancer Cells Using a Novel Modular T Cell-Retargeting System
Arndt, C.; Feldmann, A.; Koristka, S.; Cartellieri, M.; Dimmel, M.; Ehninger, A.; Ehninger, G.; Bachmann, M.
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The Prostate 74(2014), 1335-1346
DOI: 10.1002/pros.22850
A novel ex vivo Isolation and Expansion Procedure for Chimeric Antigen Receptor Engrafted Human T Cells
Cartellieri, M.; Koristka, S.; Arndt, C.; Feldmann, A.; Stamova, S.; von Bonin, M.; Töpfer, K.; Krüger, T.; Geib, M.; Michalk, I.; Temme, A.; Bornhäuser, M.; Lindemann, D.; Ehninger, G.; Bachmann, M. P.
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PLOS ONE 9(2014)4, e93745
DOI: 10.1371/journal.pone.0093745
Characterization of a novel single-chain bispecific antibody for retargeting of T cells to tumor cells via the TCR co-receptor CD8
Michalk, I.; Feldmann, A.; Koristka, S.; Arndt, C.; Cartellieri, M.; Ehninger, A.; Ehninger, G.; Bachmann, M. P.
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PLOS ONE 9(2014)4, e95517
DOI: 10.1371/journal.pone.0095517
Letter to the editor: Cytotoxic response of human regulatory 1 T cells upon T cell receptor-mediated activation – a 2 matter of purity
Koristka, S.; Cartellieri, M.; Arndt, C.; Feldmann, A.; Töpfer, K.; Michalk, I.; Temme, A.; Ehninger, G.; Bachmann, M.
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Blood Cancer Journal 4(2014), e199
DOI: 10.1038/bcj.2014.20
Visualizing inflammation activity in rheumatoid arthritis with Tc-99 m Anti-CD4-mAb fragment scintigraphy
Steinhoff, K.; Pierer, M.; Siegert, J.; Pigla, U.; Laub, R.; Hesse, S.; Seidel, W.; Sorger, D.; Seese, A.; Künstler, J.-U.; Pietzsch, H.-J.; Lincke, T.; Rullmann, M.; Emmrich, F.; Sabri, O.
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Nuclear Medicine and Biology 41(2014), 350-354
DOI: 10.1016/j.nucmedbio.2013.12.018
Influence of different chelators on the radiochemical properties of a 68-Gallium labelled bombesin analogue.
Asti, M.; Iori, M.; Capponi, P. C.; Atti, G.; Rubagotti, S.; Martin, R.; Brennauer, A.; Müller, M.; Bergmann, R.; Erba, P. A.; Versari, A.
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Nuclear Medicine and Biology 41(2014), 24-35
DOI: 10.1016/j.nucmedbio.2013.08.010
Radiolabeled anti-EGFR-antibody improves local tumor control after external beam radiotherapy and offers theragnostic potential
Koi, L.; Bergmann, R.; Brüchner, K.; Pietzsch, J.; Pietzsch, H.-J.; Krause, M.; Steinbach, J.; Zips, D.; Baumann, M.
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Radiotherapy and Oncology 110(2014), 362-369
DOI: 10.1016/j.radonc.2013.12.001
Establishment of two complementary in vitro assays for radiocopper complexes achieving reliable and comparable evaluation of in vivo stability
Zarschler, K.; Kubeil, M.; Stephan, H.
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RSC Advances 4(2014), 10157-10164
DOI: 10.1039/c3ra47302c
TCR/CD3 activation and co-stimulation combined in one T cell retargeting system improve anti-tumor immunity
Cartellieri, M.; Arndt, C.; Feldmann, A.; von Bonin, M.; Ewen, E.-M.; Koristka, S.; Michalk, I.; Stamova, S.; Berndt, N.; Gocht, A.; Bornhäuser, M.; Ehninger, G.; Schmitz, M.; Bachmann, M.
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OncoImmunology 2(2014)12, e26770
DOI: 10.4161/onci.26770
Evaluation of PET quantification accuracy in vivo - Comparison of measured FDG concentration in the bladder with urine samples / In-vivo-Evaluation der Quantifizierungsgenauigkeit der PET - Vergleich der gemessenen FDG-Konzentration in der Blase mit Urinproben
Maus, J.; Hofheinz, F.; Schramm, G.; Oehme, L.; Beuthien-Baumann, B.; Lukas, M.; Buchert, R.; Steinbach, J.; Kotzerke, J.; van den Hoff, J.
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Nuklearmedizin 53(2014), 67-77
DOI: 10.3413/Nukmed-0588-13-05
Costimulation improves the killing capability of T cells redirected to tumor cells expressing low levels of CD33: Description of a novel modular targeting system
Arndt, C.; Feldmann, A.; von Bonin, M.; Cartellieri, M.; Ewen, E.-M.; Koristka, S.; Michalk, I.; Stamova, S.; Berndt, N.; Gocht, A.; Bornhäuser, M.; Ehninger, G.; Schmitz, M.; Bachmann, M.
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Leukemia 28(2014), 59-69
DOI: 10.1038/leu.2013.243
ISSN: 0887-6924
Asymmetric Synthesis of Spirocyclic 2-Benzopyrans for Positron Emission Tomography of σ1 Receptors in the Brain
Holl, K.; Schepmann, D.; Fischer, S.; Ludwig, F. A.; Hiller, A.; Donat, C. K.; Deuther-Conrad, W.; Brust, P.; Wünsch, B.
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Pharmaceuticals 7(2014), 78-112
DOI: 10.3390/ph7010078
ISSN: 1424-8247
A volume of intersection approach for on-the-fly system matrix calculation in 3D PET image reconstruction
Lougovski, A.; Hofheinz, F.; Langner, J.; Schramm, G.; Will, E.; van den Hoff, J.
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Physics in Medicine and Biology 59(2014)3, 561-577
DOI: 10.1088/0031-9155/59/3/561
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