Contact

Dr. Torsten Knieß

Head Production of Radio­pharma­ceuticals
Targetry, Target Chemistry and Radiopharmacy
t.kniessAthzdr.de
Phone: +49 351 260 2760


Torsten Kniess' Publications

2020ORCHID ID 0000-0002-4107-3455

2024

  • Kreller, M.; Brühlmann, S.A.; Knieß, T.; Kopka, K.; Walther, M.; Production of Medical Radionuclides in the Center for Radiopharmaceutical Tumor Research - A Status Report. Instruments, 2024, 8, 10.

2023

  • Knieß, T.; Kreller, M.; Zessin, J.; Kopka, K.; Elektrophile Synthese von 6-L-[18F]FDOPA mit [18F]F2: ein Statusbericht über das Gastarget am Zyklotron TR-Flex. Nuklearmedizin, 2023, 62, 150.
  • Mäding, P.; Zessin, J.; Kreller, M.; Kopka, K.; Kniess, T.; Actions for increased yields and easier maintenance at the Tracerlab FXC-pro system in the synthesis of L-[11C]methionine. EJNMMI Radiopharmacy and Chemistry, 2023, 8 (Suppl. 1), 11
  • Brühlmann, S.A.; Walther, M.; Kreller, M.; Reissig, F.; Pietzsch, H.J.; Kniess, T.; Kopka, K.; Cyclotron-Based Production of 67-Cu for Radionuclide Theranostics via the 70Zn(p,α)67Cu Reaction. Pharmaceuticals, 2023, 16, 314.
  • Kniess, T.; Zessin, J.; Mäding, P.; Kuchar, M., Kiss, O.; Kopka, K.; Synthesis of [18F]FMISO, a hypoxia-specific imaging probe for PET, an overview from a radiochemist's perspective. EJNMMI Radiopharmacy and Chemistry, 2023, 8: 5

2020

  • Laube, M.; Gassner, C.; Neuber, C.; Wodtke, R.; Ullrich, M.; Haase-Kohn, C.; Löser, R.; Köckerling, M.; Kopka, K.; Kniess, T.; Hey-Hawkins, E.; Pietzsch, J.; Deuteration versus ethylation - strategies to improve the metabolic fate of an 18F-labeled celecoxib derivative. RSC Advances, 2020, 10, 38601-38611.

2019

  • Roscales, S.; Kniess, T.; Access to 18F-labelled isoxazoles by ruthenium-promoted 1,3-dipolar cycloaddition of 4-[18F]fluoro-N-hydroxybenzimidoyl chloride with alkynes. J Label Compd Radiopharm 2019, 62, 393-403.
  • Laube, M.; Kniess, T.; Neuber, C.; Haase-Kohn, C.; Pietzsch, J.; Fluorine-18 Labeling of S100 Proteins for Small Animal Positron Emission Tomography. Methods in Molecular Biology, vol.1929, https://doi.org/10.1007/978-1-4939-9030-6_29.
  • Roscales, S.; Bechmann, N.; Pietzsch, J.; Kniess, T.; One-pot cascade synthesis of pyrazole based isosteres of valdecoxib by a [3+2] cycloaddition sequence and evaluation of their COX inhibitory activity. Heterocycles, 2019, 98, 3, 416-428.
  • Laube, M.; Gassner, C.; Kniess, T.; Pietzsch, J.; Synthesis and Cyclooxygenase Inhibition of Sulfonamide-Substituted  (Dihydro)Pyrrolo[3,2,1-hi]indoles and Their Potential Prodrugs. Molecules, 2019, 24, 3807.
  • Kreller, M.; Pietzsch, H.J.; Walther, M.; Tietze, H.; Kaever, P.; Knieß, T.; Füchtner, F.; Steinbach, J.; Preusche, S.; Introduction of the New Center for Radiopharmaceutical Cancer Research at Helmholtz-Zentrum Dresden-Rossendorf. Instuments 2019, 3, 9; https://doi.org/10.3390/instruments3010009.
  • Bechmann, N.; Kniess, T.; Pietzsch, J.; Nitric Oxide-Releasing Selective Estrogen Receptor Modulators: A Bifunctional Approach to Improve the Therapeutic Index. J Med Chem, 2019, 62, 6525-6539.

2018

  • Kranz, M.; Bergmann, R.; Kniess, T.; Belter, B.; Neuber, C.; Cai, Z.; Deng, G.; Fischer, S.; Zhou, J.; Huang, Y.; Brust, P.; Deuther-Conrad, W.; Pietzsch, J.; Bridging from Brain to Tumor Imaging: (S)(-)- and (R)(+)-[18F]Fluspidine for Investigation of Sigma-1 Receptors in Tumor-Bearing Mice. Molecules 2018, 23, 702.
  • Roscales, S.; Bechmann, N.; Weiss, D.H.; Köckerling, M.; Pietzsch, J.; Kniess, T.; Novel valdecoxib derivatives by ruthenium(II)-promoted 1,3-dipolar cycloaddition of nitrile oxides with alkynes - synthesis and COX-2 inhibition activity. MedChemComm 2018, 9, 534-544.

2017

  • Kniess, T.; Laube, M.; Wüst, F.; Pietzsch, J.; Technetium-99m based small molecule radiopharmaceuticals and radiotracers targeting inflammation and infection. DaltonTrans 2017, 46, 14435-14451.
  • Kniess, T.; Laube, M., Steinbach, J.; "Hydrous 18F-fluoroethylation"- Leaving off the azeotropic drying. Appl Radiat Isot 2017, 127, 260-268.
  • Moldovan, R.P.; Els-Heindl, S.; Worm, D.J.; Kniess, T.; Kluge, M.; Beck-Sickinger A.G.; Deuther-Conrad, W.; Krügel, U.; Brust, P.; Development of Fluorinated Non-Ghrelin Receptor Ligands for Potential Use in Molecular Imaging. Int J Mol Sci 2017, 18, 768.

2016

  • Laube, M.; Kniess, T.; Pietzsch, J.; Development of Antioxidant COX-2 Inhibitors as Radioprotective Agents for Radiation Theraphy - A Hypothesis-Driven Review. Antioxidants 2016, 5, DOI 10.3390/antiox5020014.
  • Gassner, C.; Neuber, C.; Laube, M.; Bergmann, R.; Kniess, T.; Pietzsch, J.; Development of a 18F-labeled Diaryl-Substituted Dihydropyrrolo[3,2,1-hi]indole as Potential Probe for Functional Imaging of Cyclooxygenase-2 with PET. ChemistrySelect 2016, 1, 5812-5820.