Dr. Holger Stephan

Group leader of the Nanoscalic Systems group


Holger Stephan 2017 Address

Helmholtz-Zentrum Dresden - Rossendorf

Institute of Radiopharmaceutical Cancer Research

P.O. Box 51 01 19

D-01314 Dresden

Room Building 801/C207
Phone +49-351-260 3091
Fax +49-351-260 3232
E-Mail h.stephan@hzdr.de
Research profile ORCID and ResearcherID


1976 - 1981

Study of chemistry at the Mining Academy Freiberg


Dipl.-Chem., Mining Academy Freiberg


Ph.D. degree with Prof. J. Beger (Freiberg); Thesis: “Amido podands – synthesis and investigations of solvent extraction of metal salts”

Professional Career

1981 - 1984

Centre of Research and Technology of Microelectronics Dresden (Head of a working group)

1984 - 1989

Technical University Mining Academy Freiberg/Company of Synthetic Fibres Schwarza (Assistant research scientist)

1989 - 1993

Central Institute of Solid State Physics and Material Research Dresden (Assistant research scientist)

1994 - 1997

Technical University Dresden (Senior scientist with Prof. K. Gloe)

1998 - today

Helmholtz-Zentrum Dresden - Rossendorf (HZDR) / Institute of Radiopharmaceutical Cancer Research

Since 2005

Head of the working group “Nanoscalic Systems”

2011 - 2017

Spokesperson of the Helmholtz Virtual Institute “NanoTracking”


HZDR Research Fellow

Visiting Appointments


Institute of Chemistry and Chemical Technology Krasnojarsk (Russia)


Science University Tokyo; Kyoto Institute of Technology; Saga University (Japan)


University of British Colombia/Vancouver; University of Victoria (Canada)


JAERI (Japan Atomic Energy Research Institute) Tokai; Saga University (Japan)


Kitakyushu University, Tohoku University, TIT; JAERI (Japan)


Nikolaev Institute of Inorganic Chemistry, Novosibirsk (Russia)


Monash University, Melbourne (Australia)


Monash University, Melbourne (Australia)


Monash University, Melbourne (Australia)


Monash University, Melbourne (Australia)

Research Interests

Development and characterization of new radiotracers and extractants, functional nanomaterials for multifunctional cancer imaging, Supramolecular Chemistry, Dendrimer Chemistry, Coordination Chemistry and Thermodynamics of Liquid Two-phase Systems.

Memberships in Scholarly Societies

Gesellschaft Deutscher Chemiker, DECHEMA, Society of Radiopharmaceutical Sciences


Comprehensive experience for undertaking radiotracer experiments, different spectroscopic techniques, characterization of colloid-chemical properties and in vitro/in vivo studies in view of the development and characterization of novel radiotracers, including functionalized nanoparticles; design and development of chemically, metabolically and radiolytically stable radiometal complexes on the basis of 64Cu/67Cu is of special interest; polynuclear metal compounds (polyoxometalates, Re clusters) for anti-tumor activity, photosensitizing, and radiation-sensitizing properties are under investigation; characterization of binding and transport behavior of novel receptors by solvent extraction studies represents one main topic.