Publications of Institute of Radiopharmaceutical Cancer Research
| < | Page 1 of 3 | > | Total number to be selected: 209 Title records (100 Title records per page) |
2021
HIF2alpha-associated pseudohypoxia promotes radioresistance in pheochromocytoma: insights from 3D models
Seifert, V.; Richter, S.; Bechmann, N.; Bachmann, M.; Ziegler, C. G.; Pietzsch, J.; Ullrich, M.
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Cancers 13(2021), 385
DOI: 10.3390/cancers13030385
Screening Arrays of Laminin Peptides on Modified Cellulose for Promotion of Adhesion of Primary Endothelial and Neural Precursor Cells
Wetzel, R.; Hauser, S.; Lin, W.; Berg, P.; Werner, C.; Pietzsch, J.; Kempermann, G.; Zhang, Y.
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Advanced Biology (2021)
Online First (2021) DOI: 10.1002/adbi.201900303
Response of endothelial cells to gelatin-based hydrogels
Krüger-Genge, A.; Hauser, S.; Neffe, A. T.; Liu, Y.; Lendlein, A.; Pietzsch, J.; Jung, F.
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ACS Biomaterials Science & Engineering 7(2021), 527-540
DOI: 10.1021/acsbiomaterials.0c01432
A modular, injectable, non-covalently assembled hydrogel system features widescale tunable degradability for controlled release and tissue integration
Rothe, R.; Xu, Y.; Kuriakose Thomas, A.; Meister, S.; Zhang, Y.; Pietzsch, J.; Hauser, S.
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Biomaterials 269(2021), 120637
DOI: 10.1016/j.biomaterials.2020.120637
2020
The pyrazolo[3,4-d]pyrimidine-based kinase inhibitor NVP-BHG712: Effects of regioisomers on tumor growth, perfusion, and hypoxia in EphB4-positive A375 melanoma xenografts
Neuber, C.; Tröster, A.; Löser, R.; Belter, B.; Schwalbe, H.; Pietzsch, J.
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Molecules 25(2020), 5115
DOI: 10.3390/molecules25215115
Three-dimensional cell culture systems in radiopharmaceutical cancer research
Doctor, A.; Seifert, V.; Ullrich, M.; Hauser, S.; Pietzsch, J.
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Cancers 12(2020), 2765
DOI: 10.3390/cancers12102765
HIF2α supports pro-metastatic behavior in pheochromocytomas/paragangliomas
Bechmann, N.; Moskopp, M. L.; Ullrich, M.; Calsina, B.; Wallace, P. W.; Richter, S.; Friedemann, M.; Langton, K.; Fliedner, S. M. J.; Timmers, H. J. L. M.; Nölting, S.; Beuschlein, F.; Fassnacht, M.; Preijbisz, A.; Pacak, K.; Ghayee, H. K.; Bornstein, S. R.; Dieterich, P.; Pietzsch, J.; Wielockx, B.; Robledo, M.; Qin, N.; Eisenhofer, G.
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Endocrine-Related Cancer 27(2020)11, 625-640
DOI: 10.1530/ERC-20-0205
The influence of different artificial extracellular matrix implant coatings on the regeneration of a critical size femur defect in rats
Förster, Y.; Schulze, S.; Penk, A.; Neuber, C.; Möller, S.; Hintze, V.; Scharnweber, D.; Schnabelrauch, M.; Pietzsch, J.; Huster, D.; Rammelt, S.
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Materials Science and Engineering C 116(2020), 111157
DOI: 10.1016/j.msec.2020.111157
Recent insights in barium-131 as a diagnostic match for radium-223: cyclotron production, separation, labeling and imaging
Reissig, F.; Bauer, D.; Ullrich, M.; Kreller, M.; Pietzsch, J.; Mamat, C.; Kopka, K.; Pietzsch, H.-J.; Walther, M.
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Pharmaceuticals 13(2020)10, 272
DOI: 10.3390/ph13100272
Metabolomics, machine learning and immunohistochemistry to predict succinate dehydrogenase mutational status in phaeochromocytomas and paragangliomas
Wallace, P. W.; Conrad, C.; Brückmann, S.; Pang, Y.; Caleiras, E.; Murakami, M.; Korpershoek, E.; Zhuang, Z.; Rapizzi, E.; Kroiss, M.; Gudziol, V.; Timmers, H. J. L. M.; Mannelli, M.; Pietzsch, J.; Beuschlein, F.; Pacak, K.; Robledo, M.; Klink, B.; Peitzsch, M.; Gill, A. J.; Tischler, A. S.; de Krijger, R. R.; Papathomas, T.; Aust, D.; Eisenhofer, G.; Richter, S.
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The Journal of Pathology 251(2020), 378-387
DOI: 10.1002/path.5472
Deuteration versus ethylation – strategies to improve the metabolic fate of a 18F-labeled celecoxib derivative
Laube, M.; Gassner, C.; Neuber, C.; Wodtke, R.; Ullrich, M.; Haase-Kohn, C.; Löser, R.; Köckerling, M.; Kopka, K.; Knieß, T.; Hey-Hawkins, E.; Pietzsch, J.
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RSC Advances 10(2020), 38601-38611
DOI: 10.1039/D0RA04494F
A radiopharmacologist's and radiochemist's view on targeting the Eph/ephrin receptor tyrosine kinase system
Neuber, C.; Belter, B.; Mamat, C.; Pietzsch, J.
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ACS Omega 5(2020)27, 16318-16331
DOI: 10.1021/acsomega.0c01058
Adjuvant drug-assisted bone healing: advances and challenges in drug delivery approaches
Rothe, R.; Hauser, S.; Neuber, C.; Laube, M.; Schulze, S.; Rammelt, S.; Pietzsch, J.
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Pharmaceutics 12(2020), 428
DOI: 10.3390/pharmaceutics12050428
Synthesis, radiolabeling and first biological characterization of 18F-labeled xanthine derivatives for PET imaging of Eph receptors
Pretze, M.; Neuber, C.; Kinski, E.; Belter, B.; Köckerling, M.; Caflisch, A.; Steinbach, J.; Pietzsch, J.; Mamat, C.
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Organic & Biomolecular Chemistry 18(2020)16, 3104-3116
DOI: 10.1039/D0OB00391C
Regulation of bone regeneration
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Clinical Hemorheology and Microcirculation 73(2020)3, 379-380
DOI: 10.3233/CH-199101
Carboranyl Derivatives of Rofecoxib with Cytostatic Activity Against Human Melanoma and Colon Cancer Cells
Buzharevski, A.; Paskas, S.; Sárosi, M.-B.; Laube, M.; Lönnecke, P.; Neumann, W.; Murganić, B.; Mijatović, S.; Maksimović-Ivanić, D.; Pietzsch, J.; Hey-Hawkins, E.
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Scientific Reports 10(2020), 4827
DOI: 10.1038/s41598-020-59059-3
The sigma-1 receptor: potential role in the modulation of cellular radiation sensitivity
Belter, B.; Deuther-Conrad, W.; Hofheinz, F.; Bachmann, M.; Brust, P.; Pietzsch, J.
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Journal of Cellular Biotechnology 6(2020), 13-21
DOI: 10.3233/JCB-209007
Active Targeting of Dendritic Polyglycerols for Diagnostic Cancer Imaging
Kritee, P.; Neuber, C.; Zarschler, K.; Wodtke, J.; Meister, S.; Rainer, H.; Pietzsch, J.; Stephan, H.
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Small 16(2020)7, 1905013
DOI: 10.1002/smll.201905013
2019
Synthesis and cyclooxygenase inhibition of sulfonamide-substituted (dihydro)pyrrolo[3,2,1-hi]indoles and their potential prodrugs
Laube, M.; Gassner, C.; Knieß, T.; Pietzsch, J.
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Molecules 24(2019), 3807
DOI: 10.3390/molecules24203807
Characterization of Tissue Transglutaminase as a Potential Biomarker for Tissue Response toward Biomaterials
Hauser, S.; Wodtke, R.; Tondera, C.; Wodtke, J.; Neffe, A. T.; Hampe, J.; Lendlein, A.; Löser, R.; Pietzsch, J.
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ACS Biomaterials Science & Engineering 5(2019), 5979-5989
DOI: 10.1021/acsbiomaterials.9b01299
Current management of pheochromocytoma/paraganglioma: A guide for the practicing clinician in the era of precision medicine
Nölting, S.; Ullrich, M.; Pietzsch, J.; Ziegler, C. G.; Eisenhofer, G.; Grossman, A.; Pacak, K.
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Cancers 11(2019), 1505
DOI: 10.3390/cancers11101505
A theranostic PSMA ligand for PET imaging and retargeting of T cells expressing the universal chimeric antigen receptor UniCAR
Arndt, C.; Feldmann, A.; Koristka, S.; Schäfer, M.; Bergmann, R.; Metwasi, N.; Berndt, N.; Bachmann, D.; Kegler, A.; Schmitz, M.; Puentes-Cala, E.; Soto, J. A.; Ehninger, G.; Pietzsch, J.; Liolios, C.; Wunderlich, G.; Kotzerke, J.; Kopka, K.; Bachmann, M.
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OncoImmunology 8(2019)9, 1659095
DOI: 10.1080/2162402X.2019.1659095
Biomaterials in repairing rat femoral defects: in vivo insights from small animal positron emission tomography/computed tomography (PET/CT) studies
Neuber, C.; Schulze, S.; Förster, Y.; Hofheinz, F.; Wodke, J.; Möller, S.; Schnabelrauch, M.; Hintze, V.; Scharnweber, D.; Rammelt, S.; Pietzsch, J.
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Clinical Hemorheology and Microcirculation 73(2019), 177-194
DOI: 10.3233/CH-199208
Instant kit preparation of 68Ga-radiopharmaceuticals via the hybrid chelator DATA: clinical translation of [68Ga]Ga-DATA-TOC
Sinnes, J. P.; Nagel, J.; Waldron, B. P.; Maina, T.; Nock, B. A.; Bergmann, R. K.; Ullrich, M.; Pietzsch, J.; Bachmann, M.; Baum, P. B.; Rösch, F.
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EJNMMI Research 9(2019), 48
DOI: 10.1186/s13550-019-0516-7
Cytocompatible, Injectable, and Electroconductive Soft Adhesives with Hybrid Covalent/Noncovalent Dynamic Network
Xu, Y.; Patsis, P. A.; Hauser, S.; Voigt, D.; Rothe, R.; Günther, M.; Cui, M.; Yang, X.; Wieduwild, R.; Eckert, K.; Neinhuis, C.; Akbar, T. F.; Minev, I. R.; Pietzsch, J.; Zhang, J.
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Advanced Science 6(2019), 1802077
DOI: 10.1002/advs.201802077
Nitric oxide-releasing selective estrogen receptor modulators (NO-SERMs): a bifunctional approach to improve the therapeutic index
Bechmann, N.; Knieß, T.; Pietzsch, J.
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Journal of Medicinal Chemistry 62(2019), 6525-6539
DOI: 10.1021/acs.jmedchem.9b00171
Targeting Cyclooxygenase-2 in Pheochromocytoma and Paraganglioma: Focus on Genetic Background
Ullrich, M.; Richter, S.; Seifert, V.; Hauser, S.; Calsina, B.; Martínez-Montes, A. M.; Ter Laak, M.; Ziegler, C. G.; Timmers, H.; Eisenhofer, G.; Robledo, M.; Pietzsch, J.
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Cancers 11(2019), 743
DOI: 10.3390/cancers11060743
Adjuvant drug-assisted bone healing: Part III – Further strategies for local and systemic modulation
Rothe, R.; Schulze, S.; Neuber, C.; Hauser, S.; Rammelt, S.; Pietzsch, J.
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Clinical Hemorheology and Microcirculation 73(2019), 439-488
DOI: 10.3233/CH-199104
Adjuvant drug-assisted bone healing: Part II – Modulation of angiogenesis
Rothe, R.; Schulze, S.; Neuber, C.; Hauser, S.; Rammelt, S.; Pietzsch, J.
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Clinical Hemorheology and Microcirculation 73(2019), 409-438
DOI: 10.3233/CH-199103
Adjuvant drug-assisted bone healing: Part I – Modulation of inflammation
Rothe, R.; Schulze, S.; Neuber, C.; Hauser, S.; Rammelt, S.; Pietzsch, J.
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Clinical Hemorheology and Microcirculation 73(2019), 381-408
DOI: 10.3233/CH-199102
Impact of Extrinsic and Intrinsic Hypoxia on Catecholamine Biosynthesis in Absence or Presence of Hif2α in Pheochromocytoma Cells
Bechmann, N.; Poser, I.; Seifert, V.; Greunke, C.; Ullrich, M.; Qin, N.; Walch, A.; Peitzsch, M.; Robledo, M.; Pacak, K.; Pietzsch, J.; Richter, S.; Eisenhofer, G.
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Cancers 11(2019), 594
DOI: 10.3390/cancers11050594
Carboranyl analogues of ketoprofen with cytostatic activity against human melanoma and colon cancer cell lines
Buzharevski, A.; Paskas, S.; Laube, M.; Lönnecke, P.; Neumann, W.; Murganic, B.; Mijatovic, S.; Maksimovic-Ivanic, D.; Pietzsch, J.; Hey-Hawkins, E.
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ACS Omega 4(2019)5, 8824-8833
DOI: 10.1021/acsomega.9b00412
Limited importance of EphrinA1–ligand, Src kinase, and focal adhesion kinase in EphA2-mediated regulation of metastasis in Mel-Juso and A375 human melanoma cells
Neuber, C.; Herwig, N.; Pietzsch, J.; Belter, B.
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Journal of Cellular Biotechnology 5(2019)1, 11-26
DOI: 10.3233/JCB-189010
Regulation of A375 melanoma cell adhesion and migration by EphB4 and EphrinB2 –insights from co-culture experiments
Neuber, C.; Laube, M.; Mamat, C.; Belter, B.; Pietzsch, J.
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Journal of Cellular Biotechnology 5(2019)1, 27-42
DOI: 10.3233/JCB-189011
Radiochemical and radiopharmacological characterization of a 64Cu-labeled α-MSH analog conjugated with different chelators
Gao, F.; Sihver, W.; Bergmann, R.; Walther, M.; Stephan, H.; Belter, B.; Neuber, C.; Haase-Kohn, C.; Bolzati, C.; Pietzsch, J.; Pietzsch, H.-J.
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Journal of Labelled Compounds and Radiopharmaceuticals 62(2019)8, 495-509
DOI: 10.1002/jlcr.3728
Fluorescent Mouse Pheochromocytoma Spheroids Expressing Hypoxia-Inducible Factor 2 alpha: Morphologic and Radiopharmacologic Characterization
Seifert, V.; Liers, J.; Kniess, T.; Richter, S.; Bechmann, N.; Feldmann, A.; Bachmann, M.; Eisenhofer, G.; Pietzsch, J.; Ullrich, M.
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Journal of Cellular Biotechnology 5(2019)2, 135-151
DOI: 10.3233/JCB-199005
Carboranyl Analogues of Celecoxib with Potent Cytostatic Activity against Human Melanoma and Colon Cancer Cell Lines
Buzharevski, A.; Paskas, S.; Sárosi, M. B.; Laube, M.; Lönnecke, P.; Neumann, W.; Mijatovic, S.; Maksimovic-Ivanic, D.; Pietzsch, J.; Hey-Hawkins, E.
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ChemMedChem 14(2019)3, 315-321
DOI: 10.1002/cmdc.201800685
Fluorine-18 labeling of S100 proteins for small animal positron emission tomography
Laube, M.; Kniess, T.; Neuber, C.; Haase-Kohn, C.; Pietzsch, J.
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Methods in Molecular Biology 1929(2019), 461-485
DOI: 10.1007/978-1-4939-9030-6_29
Synthesis and preliminary radiopharmacological characterisation of an 11C-labelled azadipeptide nitrile as potential PET tracer for imaging of cysteine cathepsins
Laube, M.; Frizler, M.; Wodtke, R.; Neuber, C.; Belter, B.; Kniess, T.; Bachmann, M.; Gütschow, M.; Pietzsch, J.; Löser, R.
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Journal of Labelled Compounds and Radiopharmaceuticals 62(2019)8, 448-459
DOI: 10.1002/jlcr.3729
Synthesis, 18F-labelling and radiopharmacological characterisation of the C-terminal 30mer of Clostridium perfringens enterotoxin as a potential claudin-targeting peptide
Löser, R.; Bader, M.; Kuchar, M.; Wodtke, R.; Lenk, J.; Wodtke, J.; Kuhne, K.; Bergmann, R.; Haase-Kohn, C.; Urbanová, M.; Steinbach, J.; Pietzsch, J.
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Amino Acids 51(2019)2, 219-244
DOI: 10.1007/s00726-018-2657-9
One-pot Cascade Synthesis of Pyrazole-based Isosteres of Valdecoxib by a [3+2] Cycloaddition/[1,5] Sigmatropic Rearrangement Sequence and Evaluation of their COX Inhibitory Activity
Roscales, S.; Bechmann, N.; Pietzsch, J.; Kniess, T.
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Heterocycles 98(2019)3, 416-428
DOI: 10.3987/COM-19-14048
2018
Diverse Effects of Phospholipase A2 Receptor Expression on LNCaP and PC-3 Prostate Cancer Cell Growth in vitro and in vivo
Friedemann, M.; Nacke, B.; Hagelgans, A.; Jandeck, C.; Bechmann, N.; Ullrich, M.; Belter, B.; Neuber, C.; Sukocheva, O.; Pietzsch, J.; Menschikowski, M.
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Oncotarget 9(2018), 35983-35996
DOI: 10.18632/oncotarget.26316
Synthesis, characterization and initial biological evaluation of [⁹⁹ᵐTc]Tc-tricarbonyl labeled DPA-α-MSH peptide derivatives for potential melanoma imaging
Gao, F.; Sihver, W.; Bergmann, R.; Belter, B.; Bolzati, C.; Salvarese, N.; Steinbach, J.; Pietzsch, J.; Pietzsch, H.-J.
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ChemMedChem 13(2018)11, 1146-1158
DOI: 10.1002/cmdc.201800110
Exploring pitfalls of 64Cu‑labeled EGFR‑targeting peptide GE11 as a potential PET tracer
Striese, F.; Sihver, W.; Gao, F.; Bergmann, R.; Walther, M.; Pietzsch, J.; Steinbach, J.; Pietzsch, H.-J.
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Amino Acids 50(2018)10, 1415-1431
DOI: 10.1007/s00726-018-2616-5
Development of a novel target module redirecting UniCAR T cells to Sialyl Tn-expressing tumor cells
Loureiro, L.; Feldmann, A.; Bergmann, R.; Koristka, S.; Berndt, N.; Arndt, C.; Pietzsch, J.; Novo, C.; Videira, P.; Bachmann, M.
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Blood Cancer Journal 8(2018), 81
DOI: 10.1038/s41408-018-0113-4
Strain-specific metastatic phenotypes in pheochromocytoma allograft mice
Ullrich, M.; Liers, J.; Peitzsch, M.; Feldmann, A.; Bergmann, R.; Sommer, U.; Richter, S.; Bornstein, S. R.; Bachmann, M.; Eisenhofer, G.; Ziegler, C. G.; Pietzsch, J.
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Endocrine-Related Cancer 25(2018)12, 993-1004
DOI: 10.1530/ERC-18-0136
From mono- to bivalent: improving theranostic properties of target modules for redirection of UniCAR T cells against EGFR-expressing tumor cells in vitro and in vivo
Albert, S.; Arndt, C.; Koristka, S.; Berndt, N.; Bergmann, R.; Feldmann, A.; Schmitz, M.; Pietzsch, J.; Steinbach, J.; Bachmann, M.
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Oncotarget 9(2018)39, 25597-25616
DOI: 10.18632/oncotarget.25390
Nε-Acryloyllysine piperazides as irreversible inhibitors of transglutaminase 2 – synthesis, structure-activity relationships and pharmacokinetic profiling
Wodtke, R.; Hauser, C.; Ruiz-Gómez, G.; Jäckel, E.; Bauer, D.; Lohse, M.; Wong, A.; Pufe, J.; Ludwig, F.-A.; Fischer, S.; Hauser, S.; Greif, D.; Pisabarro, M. T.; Pietzsch, J.; Pietsch, M.; Löser, R.
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Journal of Medicinal Chemistry 61(2018)10, 4528-4560
DOI: 10.1021/acs.jmedchem.8b00286
Overexpression of receptor tyrosine kinase EphB4 triggers tumor growth and hypoxia in A375 melanoma xenografts: insights from multitracer small animal imaging experiments
Neuber, C.; Belter, B.; Meister, S.; Hofheinz, F.; Bergmann, R.; Pietzsch, H.-J.; Pietzsch, J.
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Molecules 23(2018), 444
DOI: 10.3390/molecules23020444
Bridging from Brain to Tumor imaging: (S)- and (R)-[18F]Fluspidine for investigation of Sigma-1 Receptors in Tumor-bearing Mice
Kranz, M.; Bergmann, R.; Kniess, T.; Belter, B.; Neuber, C.; Cai, Z.; Deng, G.; Fischer, S.; Steinbach, J.; Zhou, J.; Huang, H.; Brust, P.; Deuther-Conrad, W.; Pietzsch, J.
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Molecules 23(2018)3, 702
DOI: 10.3390/molecules23030702
Causative treatment of acid aspiration induced acute lung injury – recent trends from animal experiments and critical perspective
Gramatté, J.; Pietzsch, J.; Bergmann, R.; Richter, T.
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Clinical Hemorheology and Microcirculation 69(2018), 187-195
DOI: 10.3233/CH-189113
Engrafting human regulatory T cells with a flexible modular chimeric antigen receptor technology
Koristka, S.; Kegler, A.; Bergmann, R.; Arndt, C.; Feldmann, A.; Albert, S.; Cartellieri, M.; Ehninger, A.; Ehninger, G.; Middeke, J. M.; Bornhäuser, M.; Schmitz, M.; Pietzsch, J.; Akgün, K.; Ziemssen, T.; Steinbach, J.; Bachmann, M. P.
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Journal of Autoimmunity 90(2018), 116-131
DOI: 10.1016/j.jaut.2018.02.006
Evaluation of fluorine-18-labelled alpha1(I)-N-telopeptide analogues as substrate-based radiotracers for PET imaging of melanoma-associated lysyl oxidase
Kuchar, M.; Neuber, C.; Belter, B.; Bergmann, R.; Lenk, J.; Wodtke, R.; Kniess, T.; Steinbach, J.; Pietzsch, J.; Löser, R.
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Frontiers in Chemistry 6(2018), 121
DOI: 10.3389/fchem.2018.00121
Novel Valdecoxib Derivates by Ruthenium-catalyzed 1,3-Dipolar Cycloaddition of Nitrile Oxides with Alkynes - Synthesis and COX-2 Inhibition Affinity.
Roscales, S.; Bechmann, N.; Weiss, D. H.; Köckerling, M.; Pietzsch, J.; Kniess, T.
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MedChemComm 9(2018), 534-544
DOI: 10.1039/c7md00575j
2017
An orthotopic xenograft model for high-risk non-muscle invasive bladder cancer in mice: influence of mouse strain, tumor cell count, dwell time and bladder pretreatment
Huebner, D.; Rieger, C.; Bergmann, R.; Ullrich, M.; Meister, S.; Toma, M.; Wiedemuth, R.; Temme, A.; Novotny, V.; Wirth, M. P.; Bachmann, M.; Pietzsch, J.; Fuessel, S.
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BMC Cancer 17(2017)1, 790
DOI: 10.1186/s12885-017-3778-3
Biological characterization of novel nitroimidazole-peptide conjugates in vitro and in vivo.
Bergmann, R.; Splith, K.; Pietzsch, J.; Bachmann, M.; Neundorf, I.
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Journal of Peptide Science 23(2017), 597-609
DOI: 10.1002/psc.2995
Retargeting of UniCAR T cells with an in vivo synthesized target module directed against CD19 positive tumor cells
Bachmann, D.; Aliperta, R.; Bergmann, R.; Feldmann, A.; Koristka, S.; Arndt, C.; Loff, S.; Welzel, P. B.; Albert, S.; Kegler, A.; Ehninger, A.; Cartellieri, M.; Ehninger, G.; Bornhäuser, M.; von Bonin, M.; Werner, C.; Pietzsch, J.; Steinbach, J.; Bachmann, M.
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Oncotarget 9(2017), 7487-7500
DOI: 10.18632/oncotarget.23556
Development of novel target modules for retargeting of UniCAR T cells to GD2 positive tumor cells
Mitwasi, N.; Feldmann, A.; Bergmann, R.; Berndt, N.; Arndt, C.; Koristka, S.; Kegler, A.; Jureczek, J.; Hoffmann, A.; Ehninger, A.; Cartellieri, M.; Albert, S.; Rössig, C.; Ehninger, G.; Pietzsch, J.; Steinbach, J.; Bachmann, M.
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Oncotarget 8(2017), 108584-108603
DOI: 10.18632/oncotarget.21017
99mTechnetium-based Small Molecule Radiopharmaceuticals and Radiotracers Targeting Inflammation and Infection
Kniess, T.; Laube, M.; Wüst, F.; Pietzsch, J.
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Dalton Transactions 46(2017), 14435-14451
DOI: 10.1039/c7dt01735a
Preparation of a novel radiotracer targeting the EphB4 receptor via radiofluorination using spiro azetidinium salts as precursor
Wiemer, J.; Steinbach, J.; Pietzsch, J.; Mamat, C.
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Journal of Labelled Compounds and Radiopharmaceuticals 60(2017), 489-498
DOI: 10.1002/jlcr.3526
Surface charge and particle size determine the metabolic fate of dendritic polyglycerols
Pant, K.; Pufe, J.; Zarschler, K.; Bergmann, R.; Steinbach, J.; Reimann, S.; Haag, R.; Pietzsch, J.; Stephan, H.
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Nanoscale 9(2017), 8723-8739
DOI: 10.1039/C7NR01702B
A novel nanobody-based target module for retargeting of T lymphocytes to EGFR-expressing cancer cells via the modular UniCAR platform
Albert, S.; Arndt, C.; Feldmann, A.; Bergmann, R.; Bachmann, D.; Koristka, S.; Ludwig, F.; Ziller-Walter, P.; Kegler, A.; Gärtner, S.; Schmitz, M.; Ehninger, A.; Cartellieri, M.; Ehninger, G.; Pietzsch, H.-J.; Pietzsch, J.; Steinbach, J.; Bachmann, M.
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OncoImmunology 6(2017)4, e1287246
DOI: 10.1080/2162402X.2017.1287246
A novel tumor pretargeting system based on complementary L-configured oligonucleotides
Schubert, M.; Bergmann, R.; Förster, C.; Sihver, W.; Vonhoff, S.; Klussmann, S.; Bethge, L.; Walther, M.; Schlesinger, J.; Pietzsch, J.; Steinbach, J.; Pietzsch, H.-J.
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Bioconjugate Chemistry 28(2017)4, 1176-1188
DOI: 10.1021/acs.bioconjchem.7b00045
In vivo examination of an injectable hydrogel system crosslinked by peptide-oligosaccharide interaction in immunocompetent nude mice
Tondera, C.; Wieduwild, R.; Röder, E.; Werner, C.; Zhang, Y.; Pietzsch, J.
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Advanced Functional Materials 27(2017)15, 1605189
DOI: 10.1002/adfm.201605189
Retargeting of T lymphocytes to PSCA- or PSMA positive prostate cancer cells using the novel modular chimeric antigen receptor platform technology “UniCAR”
Feldmann, A.; Arndt, C.; Bergmann, R.; Loff, S.; Cartellieri, M.; Bachmann, D.; Aliperta, R.; Hetzenecker, M.; Ludwig, F.; Albert, S.; Ziller-Walter, P.; Kegler, A.; Koristka, S.; Gärtner, S.; Schmitz, M.; Ehninger, A.; Ehninger, G.; Pietzsch, J.; Steinbach, J.; Bachmann, M.
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Oncotarget 8(2017)19, 31368-31385
DOI: 10.18632/oncotarget.15572
The Why and How of Amino Acid Analytics in Cancer Diagnostics and Therapy
Manig, F.; Kuhne, K.; von Neubeck, C.; Schwarzenbolz, U.; Yu, Z.; Kessler, B. M.; Pietzsch, J.; Kunz-Schughart, L. A.
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Journal of Biotechnology 242(2017), 30-54
DOI: 10.1016/j.jbiotec.2016.12.001
Human endothelial cell models in biomaterial research
Hauser, S.; Jung, F.; Pietzsch, J.
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Trends in Biotechnology 35(2017)3, 265-277
DOI: 10.1016/j.tibtech.2016.09.007
Cryogel-Supported Stem Cell Factory for Customized Sustained Release of Bispecific Antibodies for Cancer Immunotherapy
Aliperta, R.; Welzel, P. B.; Bergmann, R.; Freudenberg, R.; Berndt, N.; Feldmann, A.; Arndt, C.; Koristka, S.; Stanzione, M.; Cartellieri, M.; Ehninger, A.; Ehninger, G.; Werner, C.; Pietzsch, J.; Steinbach, J.; Bornhäuser, M.; Bachmann, M.
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Scientific Reports 7(2017), 42855
DOI: 10.1038/srep42855
Insights into binding of S100 proteins to scavenger receptors: class B scavenger receptor CD36 binds S100A12 with high affinity
Tondera, C.; Laube, M.; Pietzsch, J.
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Amino Acids 49(2017), 183-191
DOI: 10.1007/s00726-016-2349-2
2016
Development of a F-18-labeled Diaryl-Substituted Dihydropyrrolo[3,2,1-hi]indole as Potential Probe for Functional Imaging of Cyclooxygenase-2 with PET
Gassner, C.; Neuber, C.; Laube, M.; Bergmann, R.; Kniess, T.; Pietzsch, J.
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ChemistrySelect 1(2016), 5812-5820
DOI: 10.1002/slct.201601618
Gelatin-based hydrogel degradation and tissue interaction in vivo: insights from multimodal preclinical imaging in immunocompetent nude mice
Tondera, C.; Ullm, S.; Krüger-Genge, A.; Jung, F.; Neffe, A. T.; Lendlein, A.; Klopfleisch, R.; Steinbach, J.; Neuber, C.; Pietzsch, J.
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Theranostics 6(2016)12, 2114-2128
DOI: 10.7150/thno.16614
Zwitterionic polymer-coated ultrasmall superparamagnetic iron oxide nanoparticles with low protein interaction and high biocompatibility
Pombo-García, K.; Weiss, S.; Zarschler, K.; Ang, C.-S.; Hübner, R.; Pufe, J.; Meister, S.; Seidel, J.; Pietzsch, J.; Spiccia, L.; Stephan, H.; Graham, B.
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ChemNanoMat 2(2016)10, 959-971
DOI: 10.1002/cnma.201600233
Extracellular S100A4 affects endothelial cell integrity and stimulates transmigratory behavior of human A375 melanoma cells
Herwig, N.; Belter, B.; Pietzsch, J.
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Biochemical and Biophysical Research Communications 477(2016)4, 963-969
DOI: 10.1016/j.bbrc.2016.07.009
Synthesis and kinetic characterisation of water-soluble fluorogenic acyl donors for transglutaminase 2
Wodtke, R.; Schramm, G.; Pietzsch, J.; Pietsch, M.; Löser, R.
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ChemBioChem 17(2016), 1263-1281
DOI: 10.1002/cbic.201600048
Multimodal Somatostatin Receptor Theranostics Using [64Cu]Cu-/[177Lu]Lu-DOTA-(Tyr3)octreotate and AN-238 in a Mouse Pheochromocytoma Model.
Ullrich, M.; Bergmann, R.; Peitzsch, M.; Zenker, E.; Cartellieri, M.; Bachmann, M.; Ehrhart-Bornstein, M.; Block, N.; Schally, A.; Eisenhofer, G.; Bornstein, S.; Pietzsch, J.; Ziegler, C.
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Theranostics 6(2016)5, 650-665
DOI: 10.7150/thno.14479
Development of antioxidant COX-2 inhibitors as radioprotective agents for radiation therapy – a hypothesis-driven review
Laube, M.; Kniess, T.; Pietzsch, J.
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Antioxidants 5(2016)2, 14
DOI: 10.3390/antiox5020014
5-Chloro-1-phenylpentan-1-one
Bechmann, N.; Kniess, T.; Pietzsch, J.; König, J.; Köckerling, M.
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IUCrData 1(2016), 160055
DOI: 10.1107/S2414314616000559
177Lu-labelled macrocyclic bisphosphonates for targeting bone metastasis in cancer treatment
Bergmann, R.; Meckel, M.; Kubicek, V.; Pietzsch, J.; Steinbach, J.; Hermann, P.; Rösch, F.
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EJNMMI Research 6(2016)1, 5
DOI: 10.1186/s13550-016-0161-3
Radiopharmacological characterization of 64Cu-labeled α-MSH analogs for potential use in imaging of malignant melanoma
Gao, F.; Sihver, W.; Jurischka, C.; Bergmann, R.; Haase-Kohn, C.; Belter, B.; Steinbach, J.; Carta, D.; Bolzati, C.; Calderan, A.; Pietzsch, J.; Pietzsch, H.-J.
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Amino Acids 48(2016)3, 833-847
DOI: 10.1007/s00726-015-2131-x
Interaction of extracellular S100A4 with RAGE prompts prometastatic activation of A375 melanoma cells
Herwig, N.; Belter, B.; Wolf, S.; Haase-Kohn, C.; Pietzsch, J.
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Journal of Cellular and Molecular Medicine 20(2016)5, 825-835
DOI: 10.1111/jcmm.12808
2015
Protective effects of 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitors on oxidative modification of human low density lipoproteins in vitro
Pietzsch, J.; Laube, M.; Bechmann, N.; Pietzsch, F.-J.; Kniess, T.
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Clinical Hemorheology and Microcirculation 61(2015)4, 615-632
DOI: 10.3233/CH-141923
Controlled immobilization of His-tagged proteins for protein-ligand interaction experiments using Ni2+-NTA layer on glass surfaces
Cherkouk, C.; Rebohle, L.; Lenk, J.; Keller, A.; Ou, X.; Laubec, M.; Neuber, C.; Haase-Kohn, C.; Pietzsch, J.; Skorupa, W.
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Clinical Hemorheology and Microcirculation 61(2015), 523
DOI: 10.3233/CH-151950
Influence of irradiation on release of endothelial microparticles (EMP) in vitro
Neuber, C.; Pufe, J.; Pietzsch, J.
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Clinical Hemorheology and Microcirculation 61(2015)2, 291-299
DOI: 10.3233/CH-151987
18F-Labeled 1,4-Dioxa-8-azaspiro[4.5]decane Derivative: Synthesis and Biological Evaluation of a σ1 Receptor Radioligand with Low Lipophilicity as Potent Tumor Imaging Agent
Xie, F.; Bergmann, R.; Kniess, T.; Deuther-Conrad, W.; Mamat, C.; Neuber, C.; Liu, B.; Steinbach, J.; Brust, P.; Pietzsch, J.; Jia, H.
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Journal of Medicinal Chemistry 58(2015), 5395-5407
DOI: 10.1021/acs.jmedchem.5b00593
Novel (pyrazolyl)benzenesulfonamides with a nitric oxide-releasing moiety as selective cyclooxygenase-2 inhibitors
Bechmann, N.; Kniess, T.; Köckerling, M.; Pigorsch, A.; Steinbach, J.; Pietzsch, J.
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Bioorganic & Medicinal Chemistry Letters 25(2015), 3295-3300
DOI: 10.1016/j.bmcl.2015.05.059
Cysteine cathepsins: their role in tumor progression and recent trends in the development of imaging probes
Löser, R.; Pietzsch, J.
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Frontiers in Chemistry 3(2015), 37
DOI: 10.3389/fchem.2015.00037
Copper(II) cyclam complexes with N-propionic acid pendant arms
Kubeil, M.; Zarschler, K.; Pietzsch, J.; Kraus, W.; Comba, P.; Stephan, H.
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European Journal of Inorganic Chemistry 2015(2015), 4013-4023
DOI: 10.1002/ejic.201500510
Novel indole-based sigma-2 receptor ligands: synthesis, structure–affinity relationship and antiproliferative activity
Xie, F.; Kniess, T.; Neuber, C.; Deuther-Conrad, W.; Mamat, C.; Liebermann, B. P.; Liu, B.; Mach, R. H.; Brust, P.; Steinbach, J.; Pietzsch, J.; Jia, H.
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MedChemComm 6(2015), 1093-1103
DOI: 10.1039/c5md00079c
Synthesis and Biodistribution Studies of 3H- and 64Cu-labeled Dendritic Polyglycerol and Dendritic Polyglycerol Sulfate
Pant, K.; Gröger, D.; Bergmann, R.; Pietzsch, J.; Steinbach, J.; Graham, B.; Spiccia, L.; Berthon, F.; Czarny, B.; Devel, L.; Dive, V.; Stephan, H.; Haag, R.
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Bioconjugate Chemistry 26(2015), 906-918
DOI: 10.1021/acs.bioconjchem.5b00127
Development of indazolylpyrimidine derivatives as high-affine EphB4 receptor ligands and potential PET-radiotracers
Ebert, K.; Wiemer, J.; Caballero, J.; Köckerling, M.; Steinbach, J.; Pietzsch, J.; Mamat, C.
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Bioorganic & Medicinal Chemistry 23(2015), 6025-6035
DOI: 10.1016/j.bmc.2015.06.040
Optical imaging of COX-2: Studies on an autofluorescent 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitor.
Tondera, C.; Ullm, S.; Laube, M.; Meister, S.; Neuber, C.; Mosch, B.; Kniess, T.; Pietzsch, J.
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Biochemical and Biophysical Research Communications 458(2015), 40-45
DOI: 10.1016/j.bbrc.2015.01.057
Cyclopeptides containing the DEKS motif as conformationally restricted collagen telopeptide analogues: synthesis and conformational analysis
Wodtke, R.; Ruiz-Gómez, G.; Kuchar, M.; Pisabarro, M. T.; Novotná, P.; Urbanová, M.; Steinbach, J.; Pietzsch, J.; Löser, R.
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Organic & Biomolecular Chemistry 13(2015), 1878-1896
DOI: 10.1039/C4OB02348J
Diaryl-substituted (dihydro)pyrrolo[3,2,1-hi]indoles, a class of potent COX-2 inhibitors with tricyclic core structure
Laube, M.; Gassner, C.; Sharma, S. K.; Günther, R.; Pigorsch, A.; König, J.; Köckerling, M.; Wuest, F.; Pietzsch, J.; Kniess, T.
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Journal of Organic Chemistry 80(2015), 5611-5624
DOI: 10.1021/acs.joc.5b00537
Effects of pulmonary acid aspiration on the regional pulmonary blood flow within the first hour after injury: an observational study in rats
Richter, T.; Bergmann, R.; Pietzsch, J.; Mueller, M. P.; Koch, T.
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Clinical Hemorheology and Microcirculation 60(2015), 253-262
DOI: 10.3233/CH-141867
2014
Organotypical vascular model for characterization of radioprotective compounds: Studies on antioxidant 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitors
Ullm, S.; Laube, M.; Bechmann, N.; Knieß, T.; Pietzsch, J.
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Clinical Hemorheology and Microcirculation 58(2014), 281-295
DOI: 10.3233/CH-141902
2,3-Diaryl-substituted indole based COX-2 inhibitors as leads for imaging tracer development
Laube, M.; Tondera, C.; Sharma, S. K.; Bechmann, N.; Pietzsch, F.-J.; Pigorsch, A.; Köckerling, M.; Wuest, F.; Pietzsch, J.; Kniess, T.
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RSC Advances 4(2014), 38726-38742
DOI: 10.1039/c4ra05650g
In Vivo Fluorescence Imaging and Urinary Monoamines as Surrogate Biomarkers of Disease Progression in a Mouse Model of Pheochromocytoma
Ullrich, M.; Bergmann, R.; Peitzsch, M.; Cartellieri, M.; Quin, N.; Erhart-Bornstein, M.; Block, N. L.; Schalley, A. V.; Pietzsch, J.; Eisenhofer, G.; Bornstein, S. R.; Ziegler, C. G.
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Endocrinology 155(2014), 4149-4156
DOI: 10.1210/en.2014-1431
Biocompatibility and inflammatory response in vitro and in vivo to gelatin-based biomaterials with tailorable elastic properties
Ullm, S.; Krüger, A.; Tondera, C.; Gebauer, T. P.; Neffe, A. T.; Lendlein, A.; Jung, F.; Pietzsch, J.
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Biomaterials 35(2014), 9755-9766
DOI: 10.1016/j.biomaterials.2014.08.023
Bispidine dioxotetraaza macrocycles: a new class of bispidines for 64Cu PET imaging
Comba, P.; Kubeil, M.; Pietzsch, J.; Rudolf, H.; Stephan, H.; Zarschler, K.
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Inorganic Chemistry 53(2014), 6698-6707
DOI: 10.1021/ic500476u
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