Publications of Institute of Radiopharmaceutical Cancer Research

246 Publications


Impedimetric Nanobiosensor for the Detection of SARS-CoV-2 Antigens and Antibodies

Sandoval Bojorquez, D. I.; Janićijević, Ž.; Palestina Romero, B.; Oliveros Mata, E. S.; Laube, M.; Feldmann, A.; Kegler, A.; Drewitz, L.; Fowley, C.; Pietzsch, J.; Faßbender, J.; Tonn, T.; Bachmann, M.; Baraban, L.

Solid-Phase Parallel Synthesis of Dual Histone Deacetylase-Cyclooxygenase Inhibitors

Bachmann, L. M.; Hanl, M.; Feller, F.; Sinatra, L.; Schöler, A.; Pietzsch, J.; Laube, M.; Hansen, F. K.

Carborane Analogues of Fenoprofen Exhibit Improved Antitumor Activity

Useini, L.; Mojić, M.; Laube, M.; Lönnecke, P.; Mijatović, S. S.; Maksimović-Ivanić, D.; Pietzsch, J.; Hey-Hawkins, E.

The Impact of Nε-Acryloyllysine Piperazides on the Conformational Dynamics of Transglutaminase 2

Heerwig, A.; Kick, A.; Sommerfeld, P.; Eimermacher, S.; Hartung, F.; Laube, M.; Fischer, D.; Pietzsch, H.-J.; Pietzsch, J.; Löser, R.; Mertig, M.; Pietsch, M.; Wodtke, R.

In vitro Cytostatic Effect on Tumor Cells by Carborane-based Dual Cyclooxygenase-2 and 5-Lipoxygenase Inhibitors

Braun, S.; Paskas, S.; Laube, M.; George, S.; Hofmann, B.; Lönnecke, P.; Steinhilber, D.; Pietzsch, J.; Mijatović, S. S.; Maksimović-Ivanić, D.; Hey-Hawkins, E.

Microdialysis reveals anti-inflammatory effects of sulfated glycosaminoglycanes in the early phase of bone healing

Schulze, S.; Neuber, C.; Möller, S.; Pietzsch, J.; Schaser, K.-D.; Rammelt, S.

Shell engineering in soft alginate-based capsules for culturing liver spheroids

Peng, X.; Janićijević, Ž.; Lemm, S.; Laube, M.; Pietzsch, J.; Bachmann, M.; Baraban, L.

Enzymological characterization of ⁶⁴Cu-labeled neprilysin substrates and their application for modulating the renal clearance of targeted radiopharmaceuticals

Brandt, F.; Ullrich, M.; Wodtke, J.; Kopka, K.; Bachmann, M.; Löser, R.; Pietzsch, J.; Pietzsch, H.-J.; Wodtke, R.

Epigenetic drugs in somatostatin type 2 receptor radionuclide theranostics and radiation transcriptomics in mouse pheochromocytoma models

Ullrich, M.; Richter, S.; Liers, J.; Drukewitz, S.; Friedemann, M.; Kotzerke, J.; Ziegler, C. G.; Nölting, S.; Kopka, K.; Pietzsch, J.

Significance of pulmonary endothelial injury and the role of cyclooxygenase-2 and prostanoid signaling

Nickl, R.; Hauser, S.; Pietzsch, J.; Richter, T.


Towards personalized medicine: one chelator for imaging and therapy with lutetium-177 and actinium-225

Cieslik, P.; Kubeil, M.; Zarschler, K.; Ullrich, M.; Brandt, F.; Anger, K.; Wadepohl, H.; Kopka, K.; Bachmann, M.; Pietzsch, J.; Stephan, H.; Comba, P.

  • Journal of the American Chemical Society 144(2022)47, 21555-21567
    Online First (2022) DOI: 10.1021/jacs.2c08438

Case report: Incidentally discovered case of pheochromocytoma as a cause of long COVID-19 syndrome

Ziegler, C. G.; Riediger, C.; Gruber, M.; Kunath, C.; Ullrich, M.; Pietzsch, J.; Nölting, S.; Siepmann, T.; Bornstein, S. R.; Remde, H.; Constantinescu, G.

Exploring nitric oxide (NO)- releasing celecoxib derivatives as modulators of radioresponse in pheochromocytoma cells

Brandt, F.; Ullrich, M.; Seifert, V.; Haase-Kohn, C.; Richter, S.; Knieß, T.; Pietzsch, J.; Laube, M.

Development of a neurotensin-derived 68Ga-labeled PET ligand with high in vivo stability for imaging of NTS1 receptor-expressing tumors

Schindler, L.; Moosbauer, J.; Schmidt, D.; Spruss, T.; Grätz, L.; Lüdeke, S.; Hofheinz, F.; Meister, S.; Echtenacher, B.; Bernhardt, G.; Pietzsch, J.; Hellwig, D.; Keller, M.

Cyclam with a phosphinate-bis(phosphonate) pendant arm is a bone-targeting carrier of copper radionuclides

Pazderová, L.; Benešová, M.; Havlíčková, J.; Vojtíčková, M.; Kotek, J.; Lubal, P.; Ullrich, M.; Walther, M.; Schulze, S.; Neuber, C.; Rammelt, S.; Pietzsch, H.-J.; Pietzsch, J.; Kubíček, V.; Hermann, P.

Long-term excessive dietary phosphate increases arterial blood pressure, activates the renin-angiotensin-aldosterone system, and stimulates sympathetic tone in mice

Latic, N.; Peitzsch, M.; Zupcic, A.; Pietzsch, J.; Erben, R. G.

Impact of sulfated hyaluronan on bone metabolism in diabetic Charcot neuroarthropathy and degenerative arthritis

Schulze, S.; Neuber, C.; Möller, S.; Hempel, U.; Hofbauer, L. C.; Schaser, K.-D.; Pietzsch, J.; Rammelt, S.

Investigation of radiotracer metabolic stability in vitro with CYP-overexpressing hepatoma cell lines

Lemm, S.; Köhler, S.; Wodtke, R.; Jung, F.; Küpper, J.-H.; Pietzsch, J.; Laube, M.

Personalized drug testing in human pheochromocytoma/paraganglioma primary cultures

Wang, K.; Schütze, I.; Gulde, S.; Bechmann, N.; Richter, S.; Helm, J.; Lauseker, M.; Maurer, J.; Reul, A.; Spöttl, G.; Klink, B.; William, D.; Knösel, T.; Friemel, J.; Bihl, M.; Weber, A.; Fankhauser, M.; Schober, L.; Vetter, D.; Broglie Däppen, M.; Ziegler, C. G.; Ullrich, M.; Pietzsch, J.; Bornstein, S. R.; Lottspeich, C.; Kroiß, M.; Fassnacht, M.; Wenter, V.; Ladurner, R.; Hantel, C.; Reincke, M.; Eisenhofer, G.; Grossman, A. B.; Pacak, K.; Beuschlein, F.; Auernhammer, C. J.; Pellegata, N.; Nölting, S.

Application of a fluorescence anisotropy-based assay to quantify transglutaminase 2 activity in cell lysates

Hauser, S.; Sommerfeld, P.; Wodtke, J.; Hauser, C.; Schlitterlau, P.; Pietzsch, J.; Löser, R.; Pietsch, M.; Wodtke, R.

Carboranyl analogues of mefenamic acid and their biological evaluation

Useini, L.; Mojic, M.; Laube, M.; Lönnecke, P.; Dahme, J.; Sárosi, M. B.; Mijatovic, S.; Maksimovic-Ivanic, D.; Pietzsch, J.; Hey-Hawkins, E.

A self-assembled matrix system for cell-bioengineering applications in different dimensions, scales, and geometries

Xu, Y.; Patino Gaillez, M.; Zheng, K.; Voigt, D.; Cui, M.; Kurth, T.; Xiao, L.; Rothe, R.; Hauser, S.; Lee, P. W.; Wieduwild, R.; Lin, W.; Bornhäuser, M.; Pietzsch, J.; Boccaccini, A. R.; Zhang, Y.

The role of transglutaminase 2 in the radioresistance of melanoma cells

Aepler, J.; Wodtke, J.; Wodtke, R.; Haase-Kohn, C.; Löser, R.; Pietzsch, J.; Hauser, S.

Therapeutic Potential of Nitric Oxide releasing Selective Estrogen Receptor Modulators (NO-SERMs) in Malignant Melanoma

Bechmann, N.; Calsina, B.; Richter, S.; Pietzsch, J.

“Clickable” albumin binders for modulating the tumor uptake of targeted radiopharmaceuticals

Brandt, F.; Ullrich, M.; Laube, M.; Kopka, K.; Bachmann, M.; Löser, R.; Pietzsch, J.; Pietzsch, H.-J.; van den Hoff, J.; Wodtke, R.

Tumor irradiation in mice with a laser-accelerated proton beam

Kroll, F.; Brack, F.-E.; Bernert, C.; Bock, S.; Bodenstein, E.; Brüchner, K.; Cowan, T.; Gaus, L.; Gebhardt, R.; Helbig, U.; Karsch, L.; Kluge, T.; Kraft, S.; Krause, M.; Leßmann, E.; Masood, U.; Meister, S.; Metzkes-Ng, J.; Nossula, A.; Pawelke, J.; Pietzsch, J.; Püschel, T.; Reimold, M.; Rehwald, M.; Richter, C.; Schlenvoigt, H.-P.; Schramm, U.; Umlandt, M. E. P.; Ziegler, T.; Zeil, K.; Beyreuther, E.

CRISPR/Cas9 mediated knockout of cyclooxygenase-2 gene inhibits invasiveness in A2058 melanoma cells

Haase-Kohn, C.; Laube, M.; Donat, C.; Belter, B.; Pietzsch, J.


Radiolabeled Silicon-Rhodamines as Bimodal PET/SPECT-NIR Imaging Agents

Kanagasundaram, T.; Laube, M.; Wodtke, J.; Kramer, S. C.; Stadlbauer, S.; Pietzsch, J.; Kopka, K.

Solid-phase synthesis of selectively mono-fluorobenz(o)ylated polyamines as a basis for for the Development of 18F-Labeled Radiotracers

Wodtke, R.; Pietzsch, J.; Löser, R.

Modulation of γ-secretase activity by a carborane-based flurbiprofen analogue

Saretz, S.; Basset, G.; Useini, L.; Laube, M.; Pietzsch, J.; Draca, D.; Maksimović-Ivanić, D.; Trambauer, J.; Steiner, H.; Hey-Hawkins, E.

Conductive hydrogels with dynamic reversible networks for biomedical applications

Xu, Y.; Patino Gaillez, M.; Rothe, R.; Hauser, S.; Voigt, D.; Pietzsch, J.; Zhang, Y.

Development of an 18F-labelled irreversible inhibitor of transglutaminase 2 as radiometric tool for quantitative expression profiling in cells and tissues

Wodtke, R.; Wodtke, J.; Hauser, S.; Laube, M.; Bauer, D.; Rothe, R.; Neuber, C.; Pietsch, M.; Kopka, K.; Pietzsch, J.; Löser, R.

Convergent Synthesis of Diversified Reversible Network Leads to Liquid Metal-Containing Conductive Hydrogel Adhesives

Xu, Y.; Rothe, R.; Voigt, D.; Hauser, S.; Cui, M.; Miyagawa, T.; Patino Gaillez, M.; Kurth, T.; Bornhäuser, M.; Pietzsch, J.; Zhang, X.

Development of a ghrelin receptor inverse agonist for positron emission tomography

Bergmann, R.; Chollet, C.; Els-Heindl, S.; Ullrich, M.; Berndt, N.; Pietzsch, J.; MáThé, D.; Bachmann, M.; Beck-Sickinger, A. G.

Men who stare at bone: multimodal monitoring of bone healing

Schulze, S.; Rothe, R.; Neuber, C.; Hauser, S.; Ullrich, M.; Pietzsch, J.; Rammelt, S.

HIF2alpha-associated pseudohypoxia promotes radioresistance in pheochromocytoma: insights from 3D models

Seifert, V.; Richter, S.; Bechmann, N.; Bachmann, M.; Ziegler, C. G.; Pietzsch, J.; Ullrich, M.

Screening Arrays of Laminin Peptides on Modified Cellulose for Promotion of Adhesion of Primary Endothelial and Neural Precursor Cells

Wetzel, R.; Hauser, S.; Lin, W.; Berg, P.; Werner, C.; Pietzsch, J.; Kempermann, G.; Zhang, Y.

Response of endothelial cells to gelatin-based hydrogels

Krüger-Genge, A.; Hauser, S.; Neffe, A. T.; Liu, Y.; Lendlein, A.; Pietzsch, J.; Jung, F.

Immunocompatibility and non-thrombogenicity of gelatin-based hydrogels

Krüger-Genge, A.; Tondera, C.; Hauser, S.; Braune, S.; Görs, J.; Roch, T.; Klopfleisch, R.; Neffe, A. T.; Lendlein, A.; Pietzsch, J.; Jung, F.

Radiolabelled Cyclic Bisarylmercury: High Chemical and in vivo Stability for Theranostics

Gilpin, I. M.; Ullrich, M.; Wünsche, T.; Zarschler, K.; Lebeda, O.; Pietzsch, J.; Pietzsch, H.-J.; Walther, M.

A modular, injectable, non-covalently assembled hydrogel system features widescale tunable degradability for controlled release and tissue integration

Rothe, R.; Xu, Y.; Kuriakose Thomas, A.; Meister, S.; Zhang, Y.; Pietzsch, J.; Hauser, S.


The pyrazolo[3,4-d]pyrimidine-based kinase inhibitor NVP-BHG712: Effects of regioisomers on tumor growth, perfusion, and hypoxia in EphB4-positive A375 melanoma xenografts

Neuber, C.; Tröster, A.; Löser, R.; Belter, B.; Schwalbe, H.; Pietzsch, J.

Three-dimensional cell culture systems in radiopharmaceutical cancer research

Doctor, A.; Seifert, V.; Ullrich, M.; Hauser, S.; Pietzsch, J.

HIF2α supports pro-metastatic behavior in pheochromocytomas/paragangliomas

Bechmann, N.; Moskopp, M. L.; Ullrich, M.; Calsina, B.; Wallace, P. W.; Richter, S.; Friedemann, M.; Langton, K.; Fliedner, S. M. J.; Timmers, H. J. L. M.; Nölting, S.; Beuschlein, F.; Fassnacht, M.; Preijbisz, A.; Pacak, K.; Ghayee, H. K.; Bornstein, S. R.; Dieterich, P.; Pietzsch, J.; Wielockx, B.; Robledo, M.; Qin, N.; Eisenhofer, G.

The influence of different artificial extracellular matrix implant coatings on the regeneration of a critical size femur defect in rats

Förster, Y.; Schulze, S.; Penk, A.; Neuber, C.; Möller, S.; Hintze, V.; Scharnweber, D.; Schnabelrauch, M.; Pietzsch, J.; Huster, D.; Rammelt, S.

Recent insights in barium-131 as a diagnostic match for radium-223: cyclotron production, separation, labeling and imaging

Reissig, F.; Bauer, D.; Ullrich, M.; Kreller, M.; Pietzsch, J.; Mamat, C.; Kopka, K.; Pietzsch, H.-J.; Walther, M.

Metabolomics, machine learning and immunohistochemistry to predict succinate dehydrogenase mutational status in phaeochromocytomas and paragangliomas

Wallace, P. W.; Conrad, C.; Brückmann, S.; Pang, Y.; Caleiras, E.; Murakami, M.; Korpershoek, E.; Zhuang, Z.; Rapizzi, E.; Kroiss, M.; Gudziol, V.; Timmers, H. J. L. M.; Mannelli, M.; Pietzsch, J.; Beuschlein, F.; Pacak, K.; Robledo, M.; Klink, B.; Peitzsch, M.; Gill, A. J.; Tischler, A. S.; de Krijger, R. R.; Papathomas, T.; Aust, D.; Eisenhofer, G.; Richter, S.

Deuteration versus ethylation – strategies to improve the metabolic fate of a 18F-labeled celecoxib derivative

Laube, M.; Gassner, C.; Neuber, C.; Wodtke, R.; Ullrich, M.; Haase-Kohn, C.; Löser, R.; Köckerling, M.; Kopka, K.; Knieß, T.; Hey-Hawkins, E.; Pietzsch, J.

A radiopharmacologist's and radiochemist's view on targeting the Eph/ephrin receptor tyrosine kinase system

Neuber, C.; Belter, B.; Mamat, C.; Pietzsch, J.

Adjuvant drug-assisted bone healing: advances and challenges in drug delivery approaches

Rothe, R.; Hauser, S.; Neuber, C.; Laube, M.; Schulze, S.; Rammelt, S.; Pietzsch, J.

Synthesis, radiolabeling and first biological characterization of 18F-labeled xanthine derivatives for PET imaging of Eph receptors

Pretze, M.; Neuber, C.; Kinski, E.; Belter, B.; Köckerling, M.; Caflisch, A.; Steinbach, J.; Pietzsch, J.; Mamat, C.

Regulation of bone regeneration

Jung, F.; Pietzsch, J.

Carboranyl Derivatives of Rofecoxib with Cytostatic Activity Against Human Melanoma and Colon Cancer Cells

Buzharevski, A.; Paskas, S.; Sárosi, M.-B.; Laube, M.; Lönnecke, P.; Neumann, W.; Murganić, B.; Mijatović, S.; Maksimović-Ivanić, D.; Pietzsch, J.; Hey-Hawkins, E.

The sigma-1 receptor: potential role in the modulation of cellular radiation sensitivity

Belter, B.; Deuther-Conrad, W.; Hofheinz, F.; Bachmann, M.; Brust, P.; Pietzsch, J.

Active Targeting of Dendritic Polyglycerols for Diagnostic Cancer Imaging

Kritee, P.; Neuber, C.; Zarschler, K.; Wodtke, J.; Meister, S.; Rainer, H.; Pietzsch, J.; Stephan, H.


Synthesis and cyclooxygenase inhibition of sulfonamide-substituted (dihydro)pyrrolo[3,2,1-hi]indoles and their potential prodrugs

Laube, M.; Gassner, C.; Knieß, T.; Pietzsch, J.

Characterization of Tissue Transglutaminase as a Potential Biomarker for Tissue Response toward Biomaterials

Hauser, S.; Wodtke, R.; Tondera, C.; Wodtke, J.; Neffe, A. T.; Hampe, J.; Lendlein, A.; Löser, R.; Pietzsch, J.

Current management of pheochromocytoma/paraganglioma: A guide for the practicing clinician in the era of precision medicine

Nölting, S.; Ullrich, M.; Pietzsch, J.; Ziegler, C. G.; Eisenhofer, G.; Grossman, A.; Pacak, K.

A theranostic PSMA ligand for PET imaging and retargeting of T cells expressing the universal chimeric antigen receptor UniCAR

Arndt, C.; Feldmann, A.; Koristka, S.; Schäfer, M.; Bergmann, R.; Metwasi, N.; Berndt, N.; Bachmann, D.; Kegler, A.; Schmitz, M.; Puentes-Cala, E.; Soto, J. A.; Ehninger, G.; Pietzsch, J.; Liolios, C.; Wunderlich, G.; Kotzerke, J.; Kopka, K.; Bachmann, M.

Biomaterials in repairing rat femoral defects: in vivo insights from small animal positron emission tomography/computed tomography (PET/CT) studies

Neuber, C.; Schulze, S.; Förster, Y.; Hofheinz, F.; Wodke, J.; Möller, S.; Schnabelrauch, M.; Hintze, V.; Scharnweber, D.; Rammelt, S.; Pietzsch, J.

Instant kit preparation of 68Ga-radiopharmaceuticals via the hybrid chelator DATA: clinical translation of [68Ga]Ga-DATA-TOC

Sinnes, J. P.; Nagel, J.; Waldron, B. P.; Maina, T.; Nock, B. A.; Bergmann, R. K.; Ullrich, M.; Pietzsch, J.; Bachmann, M.; Baum, P. B.; Rösch, F.

Cytocompatible, Injectable, and Electroconductive Soft Adhesives with Hybrid Covalent/Noncovalent Dynamic Network

Xu, Y.; Patsis, P. A.; Hauser, S.; Voigt, D.; Rothe, R.; Günther, M.; Cui, M.; Yang, X.; Wieduwild, R.; Eckert, K.; Neinhuis, C.; Akbar, T. F.; Minev, I. R.; Pietzsch, J.; Zhang, J.

Nitric oxide-releasing selective estrogen receptor modulators (NO-SERMs): a bifunctional approach to improve the therapeutic index

Bechmann, N.; Knieß, T.; Pietzsch, J.

Targeting Cyclooxygenase-2 in Pheochromocytoma and Paraganglioma: Focus on Genetic Background

Ullrich, M.; Richter, S.; Seifert, V.; Hauser, S.; Calsina, B.; Martínez-Montes, A. M.; Ter Laak, M.; Ziegler, C. G.; Timmers, H.; Eisenhofer, G.; Robledo, M.; Pietzsch, J.

Adjuvant drug-assisted bone healing: Part III – Further strategies for local and systemic modulation

Rothe, R.; Schulze, S.; Neuber, C.; Hauser, S.; Rammelt, S.; Pietzsch, J.

Adjuvant drug-assisted bone healing: Part II – Modulation of angiogenesis

Rothe, R.; Schulze, S.; Neuber, C.; Hauser, S.; Rammelt, S.; Pietzsch, J.

Adjuvant drug-assisted bone healing: Part I – Modulation of inflammation

Rothe, R.; Schulze, S.; Neuber, C.; Hauser, S.; Rammelt, S.; Pietzsch, J.

Impact of Extrinsic and Intrinsic Hypoxia on Catecholamine Biosynthesis in Absence or Presence of Hif2α in Pheochromocytoma Cells

Bechmann, N.; Poser, I.; Seifert, V.; Greunke, C.; Ullrich, M.; Qin, N.; Walch, A.; Peitzsch, M.; Robledo, M.; Pacak, K.; Pietzsch, J.; Richter, S.; Eisenhofer, G.

Carboranyl analogues of ketoprofen with cytostatic activity against human melanoma and colon cancer cell lines

Buzharevski, A.; Paskas, S.; Laube, M.; Lönnecke, P.; Neumann, W.; Murganic, B.; Mijatovic, S.; Maksimovic-Ivanic, D.; Pietzsch, J.; Hey-Hawkins, E.

Limited importance of EphrinA1–ligand, Src kinase, and focal adhesion kinase in EphA2-mediated regulation of metastasis in Mel-Juso and A375 human melanoma cells

Neuber, C.; Herwig, N.; Pietzsch, J.; Belter, B.

Regulation of A375 melanoma cell adhesion and migration by EphB4 and EphrinB2 –insights from co-culture experiments

Neuber, C.; Laube, M.; Mamat, C.; Belter, B.; Pietzsch, J.

  • Journal of Cellular Biotechnology 5(2019)1, 27-42
    DOI: 10.3233/JCB-189011
    ISSN: 2352-3689

Radiochemical and radiopharmacological characterization of a 64Cu-labeled α-MSH analog conjugated with different chelators

Gao, F.; Sihver, W.; Bergmann, R.; Walther, M.; Stephan, H.; Belter, B.; Neuber, C.; Haase-Kohn, C.; Bolzati, C.; Pietzsch, J.; Pietzsch, H.-J.

Fluorescent Mouse Pheochromocytoma Spheroids Expressing Hypoxia-Inducible Factor 2 alpha: Morphologic and Radiopharmacologic Characterization

Seifert, V.; Liers, J.; Kniess, T.; Richter, S.; Bechmann, N.; Feldmann, A.; Bachmann, M.; Eisenhofer, G.; Pietzsch, J.; Ullrich, M.

Carboranyl Analogues of Celecoxib with Potent Cytostatic Activity against Human Melanoma and Colon Cancer Cell Lines

Buzharevski, A.; Paskas, S.; Sárosi, M. B.; Laube, M.; Lönnecke, P.; Neumann, W.; Mijatovic, S.; Maksimovic-Ivanic, D.; Pietzsch, J.; Hey-Hawkins, E.

Fluorine-18 labeling of S100 proteins for small animal positron emission tomography

Laube, M.; Kniess, T.; Neuber, C.; Haase-Kohn, C.; Pietzsch, J.

Synthesis and preliminary radiopharmacological characterisation of an 11C-labelled azadipeptide nitrile as potential PET tracer for imaging of cysteine cathepsins

Laube, M.; Frizler, M.; Wodtke, R.; Neuber, C.; Belter, B.; Kniess, T.; Bachmann, M.; Gütschow, M.; Pietzsch, J.; Löser, R.

Synthesis, 18F-labelling and radiopharmacological characterisation of the C-terminal 30mer of Clostridium perfringens enterotoxin as a potential claudin-targeting peptide

Löser, R.; Bader, M.; Kuchar, M.; Wodtke, R.; Lenk, J.; Wodtke, J.; Kuhne, K.; Bergmann, R.; Haase-Kohn, C.; Urbanová, M.; Steinbach, J.; Pietzsch, J.

One-pot Cascade Synthesis of Pyrazole-based Isosteres of Valdecoxib by a [3+2] Cycloaddition/[1,5] Sigmatropic Rearrangement Sequence and Evaluation of their COX Inhibitory Activity

Roscales, S.; Bechmann, N.; Pietzsch, J.; Kniess, T.


Diverse Effects of Phospholipase A2 Receptor Expression on LNCaP and PC-3 Prostate Cancer Cell Growth in vitro and in vivo

Friedemann, M.; Nacke, B.; Hagelgans, A.; Jandeck, C.; Bechmann, N.; Ullrich, M.; Belter, B.; Neuber, C.; Sukocheva, O.; Pietzsch, J.; Menschikowski, M.

Synthesis, characterization and initial biological evaluation of [⁹⁹ᵐTc]Tc-tricarbonyl labeled DPA-α-MSH peptide derivatives for potential melanoma imaging

Gao, F.; Sihver, W.; Bergmann, R.; Belter, B.; Bolzati, C.; Salvarese, N.; Steinbach, J.; Pietzsch, J.; Pietzsch, H.-J.

Exploring pitfalls of 64Cu‑labeled EGFR‑targeting peptide GE11 as a potential PET tracer

Striese, F.; Sihver, W.; Gao, F.; Bergmann, R.; Walther, M.; Pietzsch, J.; Steinbach, J.; Pietzsch, H.-J.

Development of a novel target module redirecting UniCAR T cells to Sialyl Tn-expressing tumor cells

Loureiro, L.; Feldmann, A.; Bergmann, R.; Koristka, S.; Berndt, N.; Arndt, C.; Pietzsch, J.; Novo, C.; Videira, P.; Bachmann, M.

Strain-specific metastatic phenotypes in pheochromocytoma allograft mice

Ullrich, M.; Liers, J.; Peitzsch, M.; Feldmann, A.; Bergmann, R.; Sommer, U.; Richter, S.; Bornstein, S. R.; Bachmann, M.; Eisenhofer, G.; Ziegler, C. G.; Pietzsch, J.

From mono- to bivalent: improving theranostic properties of target modules for redirection of UniCAR T cells against EGFR-expressing tumor cells in vitro and in vivo

Albert, S.; Arndt, C.; Koristka, S.; Berndt, N.; Bergmann, R.; Feldmann, A.; Schmitz, M.; Pietzsch, J.; Steinbach, J.; Bachmann, M.

Nε-Acryloyllysine piperazides as irreversible inhibitors of transglutaminase 2 – synthesis, structure-activity relationships and pharmacokinetic profiling

Wodtke, R.; Hauser, C.; Ruiz-Gómez, G.; Jäckel, E.; Bauer, D.; Lohse, M.; Wong, A.; Pufe, J.; Ludwig, F.-A.; Fischer, S.; Hauser, S.; Greif, D.; Pisabarro, M. T.; Pietzsch, J.; Pietsch, M.; Löser, R.

Overexpression of receptor tyrosine kinase EphB4 triggers tumor growth and hypoxia in A375 melanoma xenografts: insights from multitracer small animal imaging experiments

Neuber, C.; Belter, B.; Meister, S.; Hofheinz, F.; Bergmann, R.; Pietzsch, H.-J.; Pietzsch, J.

Bridging from Brain to Tumor imaging: (S)- and (R)-[18F]Fluspidine for investigation of Sigma-1 Receptors in Tumor-bearing Mice

Kranz, M.; Bergmann, R.; Kniess, T.; Belter, B.; Neuber, C.; Cai, Z.; Deng, G.; Fischer, S.; Steinbach, J.; Zhou, J.; Huang, H.; Brust, P.; Deuther-Conrad, W.; Pietzsch, J.

Causative treatment of acid aspiration induced acute lung injury – recent trends from animal experiments and critical perspective

Gramatté, J.; Pietzsch, J.; Bergmann, R.; Richter, T.

Engrafting human regulatory T cells with a flexible modular chimeric antigen receptor technology

Koristka, S.; Kegler, A.; Bergmann, R.; Arndt, C.; Feldmann, A.; Albert, S.; Cartellieri, M.; Ehninger, A.; Ehninger, G.; Middeke, J. M.; Bornhäuser, M.; Schmitz, M.; Pietzsch, J.; Akgün, K.; Ziemssen, T.; Steinbach, J.; Bachmann, M. P.

Evaluation of fluorine-18-labelled alpha1(I)-N-telopeptide analogues as substrate-based radiotracers for PET imaging of melanoma-associated lysyl oxidase

Kuchar, M.; Neuber, C.; Belter, B.; Bergmann, R.; Lenk, J.; Wodtke, R.; Kniess, T.; Steinbach, J.; Pietzsch, J.; Löser, R.

Novel Valdecoxib Derivates by Ruthenium-catalyzed 1,3-Dipolar Cycloaddition of Nitrile Oxides with Alkynes - Synthesis and COX-2 Inhibition Affinity.

Roscales, S.; Bechmann, N.; Weiss, D. H.; Köckerling, M.; Pietzsch, J.; Kniess, T.


An orthotopic xenograft model for high-risk non-muscle invasive bladder cancer in mice: influence of mouse strain, tumor cell count, dwell time and bladder pretreatment

Huebner, D.; Rieger, C.; Bergmann, R.; Ullrich, M.; Meister, S.; Toma, M.; Wiedemuth, R.; Temme, A.; Novotny, V.; Wirth, M. P.; Bachmann, M.; Pietzsch, J.; Fuessel, S.

Nitric oxide-releasing selective cyclooxygenase-2 inhibitors as promising radiosensitizers in melanoma cells in vitro

Bechmann, N.; Hauser, S.; Hofheinz, F.; Kniess, T.; Pietzsch, J.

  • Open Access Logo Annals of Radiation Therapy and Oncology 1(2017)2, 1010

Biological characterization of novel nitroimidazole-peptide conjugates in vitro and in vivo.

Bergmann, R.; Splith, K.; Pietzsch, J.; Bachmann, M.; Neundorf, I.

Retargeting of UniCAR T cells with an in vivo synthesized target module directed against CD19 positive tumor cells

Bachmann, D.; Aliperta, R.; Bergmann, R.; Feldmann, A.; Koristka, S.; Arndt, C.; Loff, S.; Welzel, P. B.; Albert, S.; Kegler, A.; Ehninger, A.; Cartellieri, M.; Ehninger, G.; Bornhäuser, M.; von Bonin, M.; Werner, C.; Pietzsch, J.; Steinbach, J.; Bachmann, M.

Development of novel target modules for retargeting of UniCAR T cells to GD2 positive tumor cells

Mitwasi, N.; Feldmann, A.; Bergmann, R.; Berndt, N.; Arndt, C.; Koristka, S.; Kegler, A.; Jureczek, J.; Hoffmann, A.; Ehninger, A.; Cartellieri, M.; Albert, S.; Rössig, C.; Ehninger, G.; Pietzsch, J.; Steinbach, J.; Bachmann, M.

99mTechnetium-based Small Molecule Radiopharmaceuticals and Radiotracers Targeting Inflammation and Infection

Kniess, T.; Laube, M.; Wüst, F.; Pietzsch, J.

Preparation of a novel radiotracer targeting the EphB4 receptor via radiofluorination using spiro azetidinium salts as precursor

Wiemer, J.; Steinbach, J.; Pietzsch, J.; Mamat, C.

Surface charge and particle size determine the metabolic fate of dendritic polyglycerols

Pant, K.; Pufe, J.; Zarschler, K.; Bergmann, R.; Steinbach, J.; Reimann, S.; Haag, R.; Pietzsch, J.; Stephan, H.

A novel nanobody-based target module for retargeting of T lymphocytes to EGFR-expressing cancer cells via the modular UniCAR platform

Albert, S.; Arndt, C.; Feldmann, A.; Bergmann, R.; Bachmann, D.; Koristka, S.; Ludwig, F.; Ziller-Walter, P.; Kegler, A.; Gärtner, S.; Schmitz, M.; Ehninger, A.; Cartellieri, M.; Ehninger, G.; Pietzsch, H.-J.; Pietzsch, J.; Steinbach, J.; Bachmann, M.

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