Publications of Institute of Radiopharmaceutical Cancer Research
Involved institute: Institute of Radiopharmaceutical Cancer Research
Year of Controlling (approved, published, possibly Online First)
Articles ref. in Journals
"Online First" included
Approved and published publications
Search title/ authors: ("Pietzsch, J.")
Only approved publications
263 Publications
2024
Programmable Release of Chemotherapeutics from Ferrocene-based Injectable Hydrogels Slows Melanoma Growth
Rothe, R.; Xu, Y.; Wodtke, J.; Brandt, F.; Meister, S.; et al. (10 authors)
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Advanced Healthcare Materials (2024), 2400265
DOI: 10.1002/adhm.202400265
64Cu tumor labeling with hexadentate picolinic acid-based bispidine immunoconjugates
Kubeil, M.; Neuber, C.; Starke, M.; Arndt, C.; Rodrigues Loureiro, L. R.; et al. (11 authors)
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Chemistry - A European Journal 30(2024), e202400366
DOI: 10.1002/chem.202400366
Impact of Viscosity on Human Hepatoma Spheroids in Soft Core-Shell Microcapsules
Peng, X.; Janićijević, Ž.; Lemm, S.; Hauser, S.; Knobel, M.; et al. (8 authors)
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Advanced Healthcare Materials 11(2024)13, 2302609
DOI: 10.1002/adhm.202302609
Preclinical evaluation of an ¹⁸F-labeled Nε-acryloyllysine piperazide for covalent targeting of transglutaminase 2
Wodtke, R.; Laube, M.; Hauser, S.; Meister, S.; Ludwig, F.-A.; et al. (9 authors)
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EJNMMI Radiopharmacy and Chemistry 9(2024)1, 1
DOI: 10.1186/s41181‑023‑00231‑1
Radiosynthesis and biological evaluation of [¹⁸F]AG-120 for PET imaging of the mutant isocitrate dehydrogenase 1 in gliomas
Lai, T. H.; Wenzel, B.; Dukic-Stefanovic, S.; Teodoro, R.; Arnaud, L.; et al. (14 authors)
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European Journal of Nuclear Medicine and Molecular Imaging 51(2024), 1085-1096
Online First (2023) DOI: 10.1007/s00259-023-06515-7
Improving susceptibility of neuroendocrine tumors to radionuclide therapies: personalized approaches towards complementary treatments
Richter, S.; Steenblock, C.; Lemm, S.; Ziegler, C. G.; Bechmann, N.; et al. (8 authors)
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Theranostics 14(2024)1, 17-32
DOI: 10.7150/thno.87345
2023
Lysyl oxidases as targets for cancer therapy and diagnostic imaging
Löser, R.; Kuchar, M.; Wodtke, R.; Neuber, C.; Belter, B.; et al. (8 authors)
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ChemMedChem 18(2023)18, e202300331
DOI: 10.1002/cmdc.202300331
Synthesis and In Vitro Biological Evaluation of p-Carborane-based Di-tert-butylphenol Analogs
Braun, S.; Jelača, S.; Laube, M.; George, S.; Hofmann, B.; et al. (11 authors)
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Molecules 28(2023), 4547
DOI: 10.3390/molecules28114547
Preclinical Characterization of the 177Lu-Labeled Prostate Stem Cell Antigen (PSCA)-Specific Monoclonal Antibody 7F5
Striese, F.; Neuber, C.; Gräßel, S.; Arndt, C.; Ullrich, M.; et al. (13 authors)
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International Journal of Molecular Sciences 24(2023)11, 9420
DOI: 10.3390/ijms24119420
Carborane-based Tebufelone Analogs and their Biological Evaluation In Vitro
Braun, S.; Paskas, S.; Laube, M.; George, S.; Hofmann, B.; et al. (11 authors)
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ChemMedChem 18(2023), e202300206
DOI: 10.1002/cmdc.202300206
Specific and safe targeting of glioblastoma using switchable and logic-gated RevCAR T cells
Abdelfatah Saleh Hassan, H. A.; Mitwasi, N.; Ullrich, M.; Kubeil, M.; Toussaint, M.; et al. (17 authors)
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Frontiers in Immunology 14(2023), 1166169
DOI: 10.3389/fimmu.2023.1166169
Isonimesulide and its carborane analogues as isoform-selective COX inhibitors and antitumor agents
Useini, L.; Komazec, T.; Laube, M.; Lönnecke, P.; Schädlich, J.; et al. (9 authors)
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Advanced Therapeutics 6(2023)8, 2300117
DOI: 10.1002/adtp.202300117
Comparative saturation binding analysis of ⁶⁴Cu-labeled somatostatin analogs using cell homogenates and intact cells
Ullrich, M.; Brandt, F.; Löser, R.; Pietzsch, J.; Wodtke, R.
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ACS Omega 8(2023)26, 24003-24009
DOI: 10.1021/acsomega.3c02755
Metastatic pheochromocytoma and paraganglioma: somatostatin receptor 2 expression, genetics and therapeutic responses
Fischer, A.; Kloos, S.; Maccio, U.; Friemel, J.; Remde, H.; et al. (33 authors)
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Journal of Clinical Endocrinology and Metabolism 108(2023), 2676-2685
DOI: 10.1210/clinem/dgad166
Impedimetric Nanobiosensor for the Detection of SARS-CoV-2 Antigens and Antibodies
Sandoval Bojorquez, D. I.; Janićijević, Ž.; Palestina Romero, B.; Oliveros Mata, E. S.; Laube, M.; et al. (14 authors)
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ACS Sensors 8(2023)2, 576-586
DOI: 10.1021/acssensors.2c01686
Solid-Phase Parallel Synthesis of Dual Histone Deacetylase-Cyclooxygenase Inhibitors
Bachmann, L. M.; Hanl, M.; Feller, F.; Sinatra, L.; Schöler, A.; et al. (8 authors)
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Molecules 28(2023), 1061
DOI: 10.3390/molecules28031061
Carborane Analogues of Fenoprofen Exhibit Improved Antitumor Activity
Useini, L.; Mojić, M.; Laube, M.; Lönnecke, P.; Mijatović, S. S.; et al. (8 authors)
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ChemMedChem 18(2023), e202200583
Online First (2022) DOI: 10.1002/cmdc.202200583
The Impact of Nε-Acryloyllysine Piperazides on the Conformational Dynamics of Transglutaminase 2
Heerwig, A.; Kick, A.; Sommerfeld, P.; Eimermacher, S.; Hartung, F.; et al. (13 authors)
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International Journal of Molecular Sciences 24(2023), 1650
DOI: 10.3390/ijms24021650
In vitro Cytostatic Effect on Tumor Cells by Carborane-based Dual Cyclooxygenase-2 and 5-Lipoxygenase Inhibitors
Braun, S.; Paskas, S.; Laube, M.; George, S.; Hofmann, B.; et al. (11 authors)
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Advanced Therapeutics 6(2023), 2200252
Online First (2022) DOI: 10.1002/adtp.202200252
ISSN: 2366-3987
Microdialysis reveals anti-inflammatory effects of sulfated glycosaminoglycanes in the early phase of bone healing
Schulze, S.; Neuber, C.; Möller, S.; Pietzsch, J.; Schaser, K.-D.; et al. (6 authors)
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International Journal of Molecular Sciences 24(2023), 2077
DOI: 10.3390/ijms24032077
Shell engineering in soft alginate-based capsules for culturing liver spheroids
Peng, X.; Janićijević, Ž.; Lemm, S.; Laube, M.; Pietzsch, J.; et al. (7 authors)
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Biotechnology Journal 18(2023)6, 2200365
DOI: 10.1002/biot.202200365
A self-assembled dynamic extracellular matrix-like hydrogel system with multi-scale structures for cell bioengineering applications
Xu, Y.; Rothe, R.; Voigt, D.; Sayed, A.; Huang, C.; et al. (13 authors)
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Acta Biomaterialia 162(2023), 211-225
DOI: 10.1016/j.actbio.2023.03.015
ISSN: 1742-7061
ISSN: 1878-7568
Enzymological characterization of ⁶⁴Cu-labeled neprilysin substrates and their application for modulating the renal clearance of targeted radiopharmaceuticals
Brandt, F.; Ullrich, M.; Wodtke, J.; Kopka, K.; Bachmann, M.; et al. (9 authors)
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Journal of Medicinal Chemistry 66(2023)1, 516-537
DOI: 10.1021/acs.jmedchem.2c01472
Dipeptide-derived alkynes as potent and selective irreversible inhibitors of cysteine cathepsins
Behring, L.; Ruiz-Gomez, G.; Trapp, C.; Morales, M.; Wodtke, R.; et al. (10 authors)
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Journal of Medicinal Chemistry 66(2023)6, 3818-3851
DOI: 10.1021/acs.jmedchem.2c01360
Epigenetic drugs in somatostatin type 2 receptor radionuclide theranostics and radiation transcriptomics in mouse pheochromocytoma models
Ullrich, M.; Richter, S.; Liers, J.; Drukewitz, S.; Friedemann, M.; et al. (10 authors)
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Theranostics 13(2023)1, 278-294
DOI: 10.7150/thno.77918
Anti-cancer prodrug cyclophosphamide exerts thrombogenic effects on human venous endothelial cells independent of CYP450 activation – relevance to thrombosis
Krüger-Genge, A.; Köhler, S.; Laube, M.; Haileka, V.; Lemm, S.; et al. (12 authors)
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Cells 12(2023), 1965
DOI: 10.3390/cells12151965
Significance of pulmonary endothelial injury and the role of cyclooxygenase-2 and prostanoid signaling
Nickl, R.; Hauser, S.; Pietzsch, J.; Richter, T.
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Bioengineering 10(2023)1, 117
DOI: 10.3390/bioengineering10010117
2022
Towards personalized medicine: one chelator for imaging and therapy with lutetium-177 and actinium-225
Cieslik, P.; Kubeil, M.; Zarschler, K.; Ullrich, M.; Brandt, F.; et al. (12 authors)
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Journal of the American Chemical Society 144(2022)47, 21555-21567
DOI: 10.1021/jacs.2c08438
Case report: Incidentally discovered case of pheochromocytoma as a cause of long COVID-19 syndrome
Ziegler, C. G.; Riediger, C.; Gruber, M.; Kunath, C.; Ullrich, M.; et al. (11 authors)
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Frontiers in Endocrinology 13(2022), 967995
DOI: 10.3389/fendo.2022.967995
ISSN: 1664-2392
Exploring nitric oxide (NO)- releasing celecoxib derivatives as modulators of radioresponse in pheochromocytoma cells
Brandt, F.; Ullrich, M.; Seifert, V.; Haase-Kohn, C.; Richter, S.; et al. (8 authors)
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Molecules 27(2022), 6587
DOI: 10.3390/molecules27196587
Development of a neurotensin-derived 68Ga-labeled PET ligand with high in vivo stability for imaging of NTS1 receptor-expressing tumors
Schindler, L.; Moosbauer, J.; Schmidt, D.; Spruss, T.; Grätz, L.; et al. (13 authors)
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Cancers 14(2022), 4922
DOI: 10.3390/cancers14194922
Cyclam with a phosphinate-bis(phosphonate) pendant arm is a bone-targeting carrier of copper radionuclides
Pazderová, L.; Benešová, M.; Havlíčková, J.; Vojtíčková, M.; Kotek, J.; et al. (15 authors)
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Dalton Transactions 51(2022), 9541-9555
DOI: 10.1039/d2dt01172g
Long-term excessive dietary phosphate increases arterial blood pressure, activates the renin-angiotensin-aldosterone system, and stimulates sympathetic tone in mice
Latic, N.; Peitzsch, M.; Zupcic, A.; Pietzsch, J.; Erben, R. G.
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Biomedicines 10(2022), 2510
DOI: 10.3390/biomedicines10102510
ISSN: 2227-9059
Impact of sulfated hyaluronan on bone metabolism in diabetic Charcot neuroarthropathy and degenerative arthritis
Schulze, S.; Neuber, C.; Möller, S.; Hempel, U.; Hofbauer, L. C.; et al. (8 authors)
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International Journal of Molecular Sciences 23(2022), 15146
DOI: 10.3390/ijms232315146
ISSN: 1422-0067
Investigation of radiotracer metabolic stability in vitro with CYP-overexpressing hepatoma cell lines
Lemm, S.; Köhler, S.; Wodtke, R.; Jung, F.; Küpper, J.-H.; et al. (7 authors)
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Cells 11(2022), 2447
DOI: 10.3390/cells11152447
Personalized drug testing in human pheochromocytoma/paraganglioma primary cultures
Wang, K.; Schütze, I.; Gulde, S.; Bechmann, N.; Richter, S.; et al. (38 authors)
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Endocrine-Related Cancer 29(2022)6, 285-306
DOI: 10.1530/ERC-21-0355
ISSN: 1351-0088
Application of a fluorescence anisotropy-based assay to quantify transglutaminase 2 activity in cell lysates
Hauser, S.; Sommerfeld, P.; Wodtke, J.; Hauser, C.; Schlitterlau, P.; et al. (9 authors)
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International Journal of Molecular Sciences 23(2022)9, 4475
DOI: 10.3390/ijms23094475
Carboranyl analogues of mefenamic acid and their biological evaluation
Useini, L.; Mojic, M.; Laube, M.; Lönnecke, P.; Dahme, J.; et al. (10 authors)
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ACS Omega 7(2022), 24282-24291
DOI: 10.1021/acsomega.2c01523
A self-assembled matrix system for cell-bioengineering applications in different dimensions, scales, and geometries
Xu, Y.; Patino Gaillez, M.; Zheng, K.; Voigt, D.; Cui, M.; et al. (16 authors)
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Small 18(2022), 2104758
DOI: 10.1002/smll.202104758
The role of transglutaminase 2 in the radioresistance of melanoma cells
Aepler, J.; Wodtke, J.; Wodtke, R.; Haase-Kohn, C.; Löser, R.; et al. (7 authors)
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Cells 11(2022), 1342
DOI: 10.3390/cells11081342
ISSN: 2073-4409
Therapeutic Potential of Nitric Oxide releasing Selective Estrogen Receptor Modulators (NO-SERMs) in Malignant Melanoma
Bechmann, N.; Calsina, B.; Richter, S.; Pietzsch, J.
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Journal of Investigative Dermatology 142(2022), 2217-2227
DOI: 10.1016/j.jid.2021.12.028
ISSN: 0022-202X
“Clickable” albumin binders for modulating the tumor uptake of targeted radiopharmaceuticals
Brandt, F.; Ullrich, M.; Laube, M.; Kopka, K.; Bachmann, M.; et al. (10 authors)
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Journal of Medicinal Chemistry 66(2022)1, 710-733
Online First (2021) DOI: 10.1021/acs.jmedchem.1c01791
Tumor irradiation in mice with a laser-accelerated proton beam
Kroll, F.; Brack, F.-E.; Bernert, C.; Bock, S.; Bodenstein, E.; et al. (31 authors)
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Nature Physics 18(2022), 316-322
DOI: 10.1038/s41567-022-01520-3
CRISPR/Cas9 mediated knockout of cyclooxygenase-2 gene inhibits invasiveness in A2058 melanoma cells
Haase-Kohn, C.; Laube, M.; Donat, C.; Belter, B.; Pietzsch, J.
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Cells 11(2022)4, 749
DOI: 10.3390/cells11040749
2021
Radiolabeled Silicon-Rhodamines as Bimodal PET/SPECT-NIR Imaging Agents
Kanagasundaram, T.; Laube, M.; Wodtke, J.; Kramer, S. C.; Stadlbauer, S.; et al. (7 authors)
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Pharmaceuticals 14(2021)11, 1155
DOI: 10.3390/ph14111155
Solid-phase synthesis of selectively mono-fluorobenz(o)ylated polyamines as a basis for for the Development of 18F-Labeled Radiotracers
Wodtke, R.; Pietzsch, J.; Löser, R.
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Molecules 26(2021)22, 7012
DOI: 10.3390/molecules26227012
Modulation of γ-secretase activity by a carborane-based flurbiprofen analogue
Saretz, S.; Basset, G.; Useini, L.; Laube, M.; Pietzsch, J.; et al. (10 authors)
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Molecules 26(2021), 2843
DOI: 10.3390/molecules26102843
Conductive hydrogels with dynamic reversible networks for biomedical applications
Xu, Y.; Patino Gaillez, M.; Rothe, R.; Hauser, S.; Voigt, D.; et al. (7 authors)
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Advanced Healthcare Materials 10(2021)11, 2100012
DOI: 10.1002/adhm.202100012
Development of an 18F-labelled irreversible inhibitor of transglutaminase 2 as radiometric tool for quantitative expression profiling in cells and tissues
Wodtke, R.; Wodtke, J.; Hauser, S.; Laube, M.; Bauer, D.; et al. (11 authors)
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Journal of Medicinal Chemistry 64(2021)6, 3462-3478
DOI: 10.1021/acs.jmedchem.1c00096
Convergent Synthesis of Diversified Reversible Network Leads to Liquid Metal-Containing Conductive Hydrogel Adhesives
Xu, Y.; Rothe, R.; Voigt, D.; Hauser, S.; Cui, M.; et al. (11 authors)
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Nature Communications 12(2021), 2407
DOI: 10.1038/s41467-021-22675-2
Development of a ghrelin receptor inverse agonist for positron emission tomography
Bergmann, R.; Chollet, C.; Els-Heindl, S.; Ullrich, M.; Berndt, N.; et al. (9 authors)
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Oncotarget 12(2021)5, 33747360
DOI: 10.18632/oncotarget.27895
Men who stare at bone: multimodal monitoring of bone healing
Schulze, S.; Rothe, R.; Neuber, C.; Hauser, S.; Ullrich, M.; et al. (7 authors)
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Biological Chemistry 402(2021)11, 1397-1413
DOI: 10.1515/hsz-2021-0170
ISSN: 1431-6730
HIF2alpha-associated pseudohypoxia promotes radioresistance in pheochromocytoma: insights from 3D models
Seifert, V.; Richter, S.; Bechmann, N.; Bachmann, M.; Ziegler, C. G.; et al. (7 authors)
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Cancers 13(2021), 385
DOI: 10.3390/cancers13030385
Screening Arrays of Laminin Peptides on Modified Cellulose for Promotion of Adhesion of Primary Endothelial and Neural Precursor Cells
Wetzel, R.; Hauser, S.; Lin, W.; Berg, P.; Werner, C.; et al. (8 authors)
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Advanced Biology 5(2021), 1900303
DOI: 10.1002/adbi.201900303
ISSN: 2366-7478
Response of endothelial cells to gelatin-based hydrogels
Krüger-Genge, A.; Hauser, S.; Neffe, A. T.; Liu, Y.; Lendlein, A.; et al. (7 authors)
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ACS Biomaterials Science & Engineering 7(2021), 527-540
DOI: 10.1021/acsbiomaterials.0c01432
Immunocompatibility and non-thrombogenicity of gelatin-based hydrogels
Krüger-Genge, A.; Tondera, C.; Hauser, S.; Braune, S.; Görs, J.; et al. (11 authors)
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Clinical Hemorheology and Microcirculation 77(2021), 335-350
DOI: 10.3233/CH-201028
Radiolabelled Cyclic Bisarylmercury: High Chemical and in vivo Stability for Theranostics
Gilpin, I. M.; Ullrich, M.; Wünsche, T.; Zarschler, K.; Lebeda, O.; et al. (8 authors)
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ChemMedChem 16(2021)17, 2645-2649
DOI: 10.1002/cmdc.202100131
A modular, injectable, non-covalently assembled hydrogel system features widescale tunable degradability for controlled release and tissue integration
Rothe, R.; Xu, Y.; Kuriakose Thomas, A.; Meister, S.; Zhang, Y.; et al. (7 authors)
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Biomaterials 269(2021), 120637
DOI: 10.1016/j.biomaterials.2020.120637
2020
The pyrazolo[3,4-d]pyrimidine-based kinase inhibitor NVP-BHG712: Effects of regioisomers on tumor growth, perfusion, and hypoxia in EphB4-positive A375 melanoma xenografts
Neuber, C.; Tröster, A.; Löser, R.; Belter, B.; Schwalbe, H.; et al. (6 authors)
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Molecules 25(2020), 5115
DOI: 10.3390/molecules25215115
Three-dimensional cell culture systems in radiopharmaceutical cancer research
Doctor, A.; Seifert, V.; Ullrich, M.; Hauser, S.; Pietzsch, J.
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Cancers 12(2020), 2765
DOI: 10.3390/cancers12102765
HIF2α supports pro-metastatic behavior in pheochromocytomas/paragangliomas
Bechmann, N.; Moskopp, M. L.; Ullrich, M.; Calsina, B.; Wallace, P. W.; et al. (23 authors)
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Endocrine-Related Cancer 27(2020)11, 625-640
DOI: 10.1530/ERC-20-0205
The influence of different artificial extracellular matrix implant coatings on the regeneration of a critical size femur defect in rats
Förster, Y.; Schulze, S.; Penk, A.; Neuber, C.; Möller, S.; et al. (11 authors)
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Materials Science and Engineering C 116(2020), 111157
DOI: 10.1016/j.msec.2020.111157
Recent insights in barium-131 as a diagnostic match for radium-223: cyclotron production, separation, labeling and imaging
Reissig, F.; Bauer, D.; Ullrich, M.; Kreller, M.; Pietzsch, J.; et al. (9 authors)
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Pharmaceuticals 13(2020)10, 272
DOI: 10.3390/ph13100272
Metabolomics, machine learning and immunohistochemistry to predict succinate dehydrogenase mutational status in phaeochromocytomas and paragangliomas
Wallace, P. W.; Conrad, C.; Brückmann, S.; Pang, Y.; Caleiras, E.; et al. (26 authors)
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The Journal of Pathology 251(2020), 378-387
DOI: 10.1002/path.5472
ISSN: 1096-9896
Deuteration versus ethylation – strategies to improve the metabolic fate of a 18F-labeled celecoxib derivative
Laube, M.; Gassner, C.; Neuber, C.; Wodtke, R.; Ullrich, M.; et al. (12 authors)
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RSC Advances 10(2020), 38601-38611
DOI: 10.1039/D0RA04494F
A radiopharmacologist's and radiochemist's view on targeting the Eph/ephrin receptor tyrosine kinase system
Neuber, C.; Belter, B.; Mamat, C.; Pietzsch, J.
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ACS Omega 5(2020)27, 16318-16331
DOI: 10.1021/acsomega.0c01058
Adjuvant drug-assisted bone healing: advances and challenges in drug delivery approaches
Rothe, R.; Hauser, S.; Neuber, C.; Laube, M.; Schulze, S.; et al. (7 authors)
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Pharmaceutics 12(2020), 428
DOI: 10.3390/pharmaceutics12050428
ISSN: 1999-4923
Synthesis, radiolabeling and first biological characterization of 18F-labeled xanthine derivatives for PET imaging of Eph receptors
Pretze, M.; Neuber, C.; Kinski, E.; Belter, B.; Köckerling, M.; et al. (9 authors)
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Organic & Biomolecular Chemistry 18(2020)16, 3104-3116
DOI: 10.1039/D0OB00391C
Regulation of bone regeneration
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Clinical Hemorheology and Microcirculation 73(2020)3, 379-380
DOI: 10.3233/CH-199101
ISSN: 1386-0291
Carboranyl Derivatives of Rofecoxib with Cytostatic Activity Against Human Melanoma and Colon Cancer Cells
Buzharevski, A.; Paskas, S.; Sárosi, M.-B.; Laube, M.; Lönnecke, P.; et al. (11 authors)
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Scientific Reports 10(2020), 4827
DOI: 10.1038/s41598-020-59059-3
The sigma-1 receptor: potential role in the modulation of cellular radiation sensitivity
Belter, B.; Deuther-Conrad, W.; Hofheinz, F.; Bachmann, M.; Brust, P.; et al. (6 authors)
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Journal of Cellular Biotechnology 6(2020), 13-21
DOI: 10.3233/JCB-209007
Active Targeting of Dendritic Polyglycerols for Diagnostic Cancer Imaging
Kritee, P.; Neuber, C.; Zarschler, K.; Wodtke, J.; Meister, S.; et al. (8 authors)
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Small 16(2020)7, 1905013
Online First (2019) DOI: 10.1002/smll.201905013
2019
Synthesis and cyclooxygenase inhibition of sulfonamide-substituted (dihydro)pyrrolo[3,2,1-hi]indoles and their potential prodrugs
Laube, M.; Gassner, C.; Knieß, T.; Pietzsch, J.
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Molecules 24(2019), 3807
DOI: 10.3390/molecules24203807
Characterization of Tissue Transglutaminase as a Potential Biomarker for Tissue Response toward Biomaterials
Hauser, S.; Wodtke, R.; Tondera, C.; Wodtke, J.; Neffe, A. T.; et al. (9 authors)
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ACS Biomaterials Science & Engineering 5(2019), 5979-5989
DOI: 10.1021/acsbiomaterials.9b01299
ISSN: 2373-9878
Current management of pheochromocytoma/paraganglioma: A guide for the practicing clinician in the era of precision medicine
Nölting, S.; Ullrich, M.; Pietzsch, J.; Ziegler, C. G.; Eisenhofer, G.; et al. (7 authors)
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Cancers 11(2019), 1505
DOI: 10.3390/cancers11101505
ISSN: 2072-6694
A theranostic PSMA ligand for PET imaging and retargeting of T cells expressing the universal chimeric antigen receptor UniCAR
Arndt, C.; Feldmann, A.; Koristka, S.; Schäfer, M.; Bergmann, R.; et al. (19 authors)
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OncoImmunology 8(2019)9, 1659095
DOI: 10.1080/2162402X.2019.1659095
Biomaterials in repairing rat femoral defects: in vivo insights from small animal positron emission tomography/computed tomography (PET/CT) studies
Neuber, C.; Schulze, S.; Förster, Y.; Hofheinz, F.; Wodke, J.; et al. (11 authors)
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Clinical Hemorheology and Microcirculation 73(2019), 177-194
DOI: 10.3233/CH-199208
Instant kit preparation of 68Ga-radiopharmaceuticals via the hybrid chelator DATA: clinical translation of [68Ga]Ga-DATA-TOC
Sinnes, J. P.; Nagel, J.; Waldron, B. P.; Maina, T.; Nock, B. A.; et al. (11 authors)
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EJNMMI Research 9(2019), 48
DOI: 10.1186/s13550-019-0516-7
Cytocompatible, Injectable, and Electroconductive Soft Adhesives with Hybrid Covalent/Noncovalent Dynamic Network
Xu, Y.; Patsis, P. A.; Hauser, S.; Voigt, D.; Rothe, R.; et al. (15 authors)
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Advanced Science 6(2019), 1802077
DOI: 10.1002/advs.201802077
Nitric oxide-releasing selective estrogen receptor modulators (NO-SERMs): a bifunctional approach to improve the therapeutic index
Bechmann, N.; Knieß, T.; Pietzsch, J.
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Journal of Medicinal Chemistry 62(2019), 6525-6539
DOI: 10.1021/acs.jmedchem.9b00171
ISSN: 0022-2623
Targeting Cyclooxygenase-2 in Pheochromocytoma and Paraganglioma: Focus on Genetic Background
Ullrich, M.; Richter, S.; Seifert, V.; Hauser, S.; Calsina, B.; et al. (12 authors)
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Cancers 11(2019), 743
DOI: 10.3390/cancers11060743
ISSN: 2072-6694
Adjuvant drug-assisted bone healing: Part III – Further strategies for local and systemic modulation
Rothe, R.; Schulze, S.; Neuber, C.; Hauser, S.; Rammelt, S.; et al. (6 authors)
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Clinical Hemorheology and Microcirculation 73(2019), 439-488
DOI: 10.3233/CH-199104
ISSN: 1386-0291
Adjuvant drug-assisted bone healing: Part II – Modulation of angiogenesis
Rothe, R.; Schulze, S.; Neuber, C.; Hauser, S.; Rammelt, S.; et al. (6 authors)
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Clinical Hemorheology and Microcirculation 73(2019), 409-438
DOI: 10.3233/CH-199103
ISSN: 1386-0291
Adjuvant drug-assisted bone healing: Part I – Modulation of inflammation
Rothe, R.; Schulze, S.; Neuber, C.; Hauser, S.; Rammelt, S.; et al. (6 authors)
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Clinical Hemorheology and Microcirculation 73(2019), 381-408
DOI: 10.3233/CH-199102
ISSN: 1386-0291
Impact of Extrinsic and Intrinsic Hypoxia on Catecholamine Biosynthesis in Absence or Presence of Hif2α in Pheochromocytoma Cells
Bechmann, N.; Poser, I.; Seifert, V.; Greunke, C.; Ullrich, M.; et al. (13 authors)
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Cancers 11(2019), 594
DOI: 10.3390/cancers11050594
ISSN: 2072-6694
Carboranyl analogues of ketoprofen with cytostatic activity against human melanoma and colon cancer cell lines
Buzharevski, A.; Paskas, S.; Laube, M.; Lönnecke, P.; Neumann, W.; et al. (10 authors)
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ACS Omega 4(2019)5, 8824-8833
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Limited importance of EphrinA1–ligand, Src kinase, and focal adhesion kinase in EphA2-mediated regulation of metastasis in Mel-Juso and A375 human melanoma cells
Neuber, C.; Herwig, N.; Pietzsch, J.; Belter, B.
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Journal of Cellular Biotechnology 5(2019)1, 11-26
DOI: 10.3233/JCB-189010
ISSN: 2352-3689
Regulation of A375 melanoma cell adhesion and migration by EphB4 and EphrinB2 –insights from co-culture experiments
Neuber, C.; Laube, M.; Mamat, C.; Belter, B.; Pietzsch, J.
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Journal of Cellular Biotechnology 5(2019)1, 27-42
DOI: 10.3233/JCB-189011
ISSN: 2352-3689
Radiochemical and radiopharmacological characterization of a 64Cu-labeled α-MSH analog conjugated with different chelators
Gao, F.; Sihver, W.; Bergmann, R.; Walther, M.; Stephan, H.; et al. (11 authors)
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Journal of Labelled Compounds and Radiopharmaceuticals 62(2019)8, 495-509
DOI: 10.1002/jlcr.3728
Fluorescent Mouse Pheochromocytoma Spheroids Expressing Hypoxia-Inducible Factor 2 alpha: Morphologic and Radiopharmacologic Characterization
Seifert, V.; Liers, J.; Kniess, T.; Richter, S.; Bechmann, N.; et al. (10 authors)
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Journal of Cellular Biotechnology 5(2019)2, 135-151
DOI: 10.3233/JCB-199005
ISSN: 2352-3689
Carboranyl Analogues of Celecoxib with Potent Cytostatic Activity against Human Melanoma and Colon Cancer Cell Lines
Buzharevski, A.; Paskas, S.; Sárosi, M. B.; Laube, M.; Lönnecke, P.; et al. (10 authors)
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ChemMedChem 14(2019)3, 315-321
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Fluorine-18 labeling of S100 proteins for small animal positron emission tomography
Laube, M.; Kniess, T.; Neuber, C.; Haase-Kohn, C.; Pietzsch, J.
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Methods in Molecular Biology 1929(2019), 461-485
DOI: 10.1007/978-1-4939-9030-6_29
ISSN: 1064-3745
Synthesis and preliminary radiopharmacological characterisation of an 11C-labelled azadipeptide nitrile as potential PET tracer for imaging of cysteine cathepsins
Laube, M.; Frizler, M.; Wodtke, R.; Neuber, C.; Belter, B.; et al. (10 authors)
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Journal of Labelled Compounds and Radiopharmaceuticals 62(2019)8, 448-459
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Synthesis, 18F-labelling and radiopharmacological characterisation of the C-terminal 30mer of Clostridium perfringens enterotoxin as a potential claudin-targeting peptide
Löser, R.; Bader, M.; Kuchar, M.; Wodtke, R.; Lenk, J.; et al. (12 authors)
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Amino Acids 51(2019)2, 219-244
Online First (2018) DOI: 10.1007/s00726-018-2657-9
One-pot Cascade Synthesis of Pyrazole-based Isosteres of Valdecoxib by a [3+2] Cycloaddition/[1,5] Sigmatropic Rearrangement Sequence and Evaluation of their COX Inhibitory Activity
Roscales, S.; Bechmann, N.; Pietzsch, J.; Kniess, T.
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Heterocycles 98(2019)3, 416-428
DOI: 10.3987/COM-19-14048
2018
Diverse Effects of Phospholipase A2 Receptor Expression on LNCaP and PC-3 Prostate Cancer Cell Growth in vitro and in vivo
Friedemann, M.; Nacke, B.; Hagelgans, A.; Jandeck, C.; Bechmann, N.; et al. (11 authors)
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Oncotarget 9(2018), 35983-35996
DOI: 10.18632/oncotarget.26316
Synthesis, characterization and initial biological evaluation of [⁹⁹ᵐTc]Tc-tricarbonyl labeled DPA-α-MSH peptide derivatives for potential melanoma imaging
Gao, F.; Sihver, W.; Bergmann, R.; Belter, B.; Bolzati, C.; et al. (9 authors)
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ChemMedChem 13(2018)11, 1146-1158
DOI: 10.1002/cmdc.201800110
Exploring pitfalls of 64Cu‑labeled EGFR‑targeting peptide GE11 as a potential PET tracer
Striese, F.; Sihver, W.; Gao, F.; Bergmann, R.; Walther, M.; et al. (8 authors)
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Amino Acids 50(2018)10, 1415-1431
DOI: 10.1007/s00726-018-2616-5
Development of a novel target module redirecting UniCAR T cells to Sialyl Tn-expressing tumor cells
Loureiro, L.; Feldmann, A.; Bergmann, R.; Koristka, S.; Berndt, N.; et al. (10 authors)
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Blood Cancer Journal 8(2018), 81
DOI: 10.1038/s41408-018-0113-4
Strain-specific metastatic phenotypes in pheochromocytoma allograft mice
Ullrich, M.; Liers, J.; Peitzsch, M.; Feldmann, A.; Bergmann, R.; et al. (12 authors)
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Endocrine-Related Cancer 25(2018)12, 993-1004
DOI: 10.1530/ERC-18-0136
From mono- to bivalent: improving theranostic properties of target modules for redirection of UniCAR T cells against EGFR-expressing tumor cells in vitro and in vivo
Albert, S.; Arndt, C.; Koristka, S.; Berndt, N.; Bergmann, R.; et al. (10 authors)
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Oncotarget 9(2018)39, 25597-25616
DOI: 10.18632/oncotarget.25390
Nε-Acryloyllysine piperazides as irreversible inhibitors of transglutaminase 2 – synthesis, structure-activity relationships and pharmacokinetic profiling
Wodtke, R.; Hauser, C.; Ruiz-Gómez, G.; Jäckel, E.; Bauer, D.; et al. (16 authors)
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Journal of Medicinal Chemistry 61(2018)10, 4528-4560
DOI: 10.1021/acs.jmedchem.8b00286
Overexpression of receptor tyrosine kinase EphB4 triggers tumor growth and hypoxia in A375 melanoma xenografts: insights from multitracer small animal imaging experiments
Neuber, C.; Belter, B.; Meister, S.; Hofheinz, F.; Bergmann, R.; et al. (7 authors)
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Molecules 23(2018), 444
DOI: 10.3390/molecules23020444
Bridging from Brain to Tumor imaging: (S)- and (R)-[18F]Fluspidine for investigation of Sigma-1 Receptors in Tumor-bearing Mice
Kranz, M.; Bergmann, R.; Kniess, T.; Belter, B.; Neuber, C.; et al. (14 authors)
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Molecules 23(2018)3, 702
DOI: 10.3390/molecules23030702
Causative treatment of acid aspiration induced acute lung injury – recent trends from animal experiments and critical perspective
Gramatté, J.; Pietzsch, J.; Bergmann, R.; Richter, T.
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Clinical Hemorheology and Microcirculation 69(2018), 187-195
DOI: 10.3233/CH-189113
ISSN: 1386-0291
Engrafting human regulatory T cells with a flexible modular chimeric antigen receptor technology
Koristka, S.; Kegler, A.; Bergmann, R.; Arndt, C.; Feldmann, A.; et al. (17 authors)
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Journal of Autoimmunity 90(2018), 116-131
DOI: 10.1016/j.jaut.2018.02.006
Evaluation of fluorine-18-labelled alpha1(I)-N-telopeptide analogues as substrate-based radiotracers for PET imaging of melanoma-associated lysyl oxidase
Kuchar, M.; Neuber, C.; Belter, B.; Bergmann, R.; Lenk, J.; et al. (10 authors)
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Frontiers in Chemistry 6(2018), 121
DOI: 10.3389/fchem.2018.00121
Novel Valdecoxib Derivates by Ruthenium-catalyzed 1,3-Dipolar Cycloaddition of Nitrile Oxides with Alkynes - Synthesis and COX-2 Inhibition Affinity.
Roscales, S.; Bechmann, N.; Weiss, D. H.; Köckerling, M.; Pietzsch, J.; et al. (6 authors)
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MedChemComm 9(2018), 534-544
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2017
An orthotopic xenograft model for high-risk non-muscle invasive bladder cancer in mice: influence of mouse strain, tumor cell count, dwell time and bladder pretreatment
Huebner, D.; Rieger, C.; Bergmann, R.; Ullrich, M.; Meister, S.; et al. (13 authors)
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BMC Cancer 17(2017)1, 790
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Biological characterization of novel nitroimidazole-peptide conjugates in vitro and in vivo.
Bergmann, R.; Splith, K.; Pietzsch, J.; Bachmann, M.; Neundorf, I.
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Journal of Peptide Science 23(2017), 597-609
DOI: 10.1002/psc.2995
Retargeting of UniCAR T cells with an in vivo synthesized target module directed against CD19 positive tumor cells
Bachmann, D.; Aliperta, R.; Bergmann, R.; Feldmann, A.; Koristka, S.; et al. (19 authors)
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Oncotarget 9(2017), 7487-7500
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Development of novel target modules for retargeting of UniCAR T cells to GD2 positive tumor cells
Mitwasi, N.; Feldmann, A.; Bergmann, R.; Berndt, N.; Arndt, C.; et al. (17 authors)
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Oncotarget 8(2017), 108584-108603
DOI: 10.18632/oncotarget.21017
99mTechnetium-based Small Molecule Radiopharmaceuticals and Radiotracers Targeting Inflammation and Infection
Kniess, T.; Laube, M.; Wüst, F.; Pietzsch, J.
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Dalton Transactions 46(2017), 14435-14451
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Preparation of a novel radiotracer targeting the EphB4 receptor via radiofluorination using spiro azetidinium salts as precursor
Wiemer, J.; Steinbach, J.; Pietzsch, J.; Mamat, C.
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Journal of Labelled Compounds and Radiopharmaceuticals 60(2017), 489-498
DOI: 10.1002/jlcr.3526
Surface charge and particle size determine the metabolic fate of dendritic polyglycerols
Pant, K.; Pufe, J.; Zarschler, K.; Bergmann, R.; Steinbach, J.; et al. (9 authors)
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Nanoscale 9(2017), 8723-8739
DOI: 10.1039/C7NR01702B
A novel nanobody-based target module for retargeting of T lymphocytes to EGFR-expressing cancer cells via the modular UniCAR platform
Albert, S.; Arndt, C.; Feldmann, A.; Bergmann, R.; Bachmann, D.; et al. (18 authors)
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OncoImmunology 6(2017)4, e1287246
DOI: 10.1080/2162402X.2017.1287246
ISSN: 2162-402X
A novel tumor pretargeting system based on complementary L-configured oligonucleotides
Schubert, M.; Bergmann, R.; Förster, C.; Sihver, W.; Vonhoff, S.; et al. (12 authors)
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Bioconjugate Chemistry 28(2017)4, 1176-1188
DOI: 10.1021/acs.bioconjchem.7b00045
In vivo examination of an injectable hydrogel system crosslinked by peptide-oligosaccharide interaction in immunocompetent nude mice
Tondera, C.; Wieduwild, R.; Röder, E.; Werner, C.; Zhang, Y.; et al. (6 authors)
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Advanced Functional Materials 27(2017)15, 1605189
DOI: 10.1002/adfm.201605189
Retargeting of T lymphocytes to PSCA- or PSMA positive prostate cancer cells using the novel modular chimeric antigen receptor platform technology “UniCAR”
Feldmann, A.; Arndt, C.; Bergmann, R.; Loff, S.; Cartellieri, M.; et al. (20 authors)
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Oncotarget 8(2017)19, 31368-31385
DOI: 10.18632/oncotarget.15572
The Why and How of Amino Acid Analytics in Cancer Diagnostics and Therapy
Manig, F.; Kuhne, K.; von Neubeck, C.; Schwarzenbolz, U.; Yu, Z.; et al. (8 authors)
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Journal of Biotechnology 242(2017), 30-54
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Human endothelial cell models in biomaterial research
Hauser, S.; Jung, F.; Pietzsch, J.
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Trends in Biotechnology 35(2017)3, 265-277
DOI: 10.1016/j.tibtech.2016.09.007
Cryogel-Supported Stem Cell Factory for Customized Sustained Release of Bispecific Antibodies for Cancer Immunotherapy
Aliperta, R.; Welzel, P. B.; Bergmann, R.; Freudenberg, R.; Berndt, N.; et al. (17 authors)
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Scientific Reports 7(2017), 42855
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Insights into binding of S100 proteins to scavenger receptors: class B scavenger receptor CD36 binds S100A12 with high affinity
Tondera, C.; Laube, M.; Pietzsch, J.
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Amino Acids 49(2017), 183-191
Online First (2016) DOI: 10.1007/s00726-016-2349-2
2016
Development of a F-18-labeled Diaryl-Substituted Dihydropyrrolo[3,2,1-hi]indole as Potential Probe for Functional Imaging of Cyclooxygenase-2 with PET
Gassner, C.; Neuber, C.; Laube, M.; Bergmann, R.; Kniess, T.; et al. (6 authors)
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ChemistrySelect 1(2016), 5812-5820
DOI: 10.1002/slct.201601618
ISSN: 2365-6549
Gelatin-based hydrogel degradation and tissue interaction in vivo: insights from multimodal preclinical imaging in immunocompetent nude mice
Tondera, C.; Ullm, S.; Krüger-Genge, A.; Jung, F.; Neffe, A. T.; et al. (10 authors)
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Theranostics 6(2016)12, 2114-2128
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Zwitterionic polymer-coated ultrasmall superparamagnetic iron oxide nanoparticles with low protein interaction and high biocompatibility
Pombo-García, K.; Weiss, S.; Zarschler, K.; Ang, C.-S.; Hübner, R.; et al. (12 authors)
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ChemNanoMat 2(2016)10, 959-971
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Extracellular S100A4 affects endothelial cell integrity and stimulates transmigratory behavior of human A375 melanoma cells
Herwig, N.; Belter, B.; Pietzsch, J.
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Biochemical and Biophysical Research Communications 477(2016)4, 963-969
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Synthesis and kinetic characterisation of water-soluble fluorogenic acyl donors for transglutaminase 2
Wodtke, R.; Schramm, G.; Pietzsch, J.; Pietsch, M.; Löser, R.
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ChemBioChem 17(2016), 1263-1281
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Multimodal Somatostatin Receptor Theranostics Using [64Cu]Cu-/[177Lu]Lu-DOTA-(Tyr3)octreotate and AN-238 in a Mouse Pheochromocytoma Model.
Ullrich, M.; Bergmann, R.; Peitzsch, M.; Zenker, E.; Cartellieri, M.; et al. (13 authors)
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Theranostics 6(2016)5, 650-665
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Development of antioxidant COX-2 inhibitors as radioprotective agents for radiation therapy – a hypothesis-driven review
Laube, M.; Kniess, T.; Pietzsch, J.
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Antioxidants 5(2016)2, 14
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5-Chloro-1-phenylpentan-1-one
Bechmann, N.; Kniess, T.; Pietzsch, J.; König, J.; Köckerling, M.
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IUCrData 1(2016), 160055
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ISSN: 2414-3146
177Lu-labelled macrocyclic bisphosphonates for targeting bone metastasis in cancer treatment
Bergmann, R.; Meckel, M.; Kubicek, V.; Pietzsch, J.; Steinbach, J.; et al. (7 authors)
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EJNMMI Research 6(2016)1, 5
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Radiopharmacological characterization of 64Cu-labeled α-MSH analogs for potential use in imaging of malignant melanoma
Gao, F.; Sihver, W.; Jurischka, C.; Bergmann, R.; Haase-Kohn, C.; et al. (12 authors)
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Amino Acids 48(2016)3, 833-847
Online First (2015) DOI: 10.1007/s00726-015-2131-x
Interaction of extracellular S100A4 with RAGE prompts prometastatic activation of A375 melanoma cells
Herwig, N.; Belter, B.; Wolf, S.; Haase-Kohn, C.; Pietzsch, J.
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Journal of Cellular and Molecular Medicine 20(2016)5, 825-835
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2015
Protective effects of 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitors on oxidative modification of human low density lipoproteins in vitro
Pietzsch, J.; Laube, M.; Bechmann, N.; Pietzsch, F.-J.; Kniess, T.
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Clinical Hemorheology and Microcirculation 61(2015)4, 615-632
DOI: 10.3233/CH-141923
ISSN: 1386-0291
Controlled immobilization of His-tagged proteins for protein-ligand interaction experiments using Ni2+-NTA layer on glass surfaces
Cherkouk, C.; Rebohle, L.; Lenk, J.; Keller, A.; Ou, X.; et al. (10 authors)
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Clinical Hemorheology and Microcirculation 61(2015), 523
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Influence of irradiation on release of endothelial microparticles (EMP) in vitro
Neuber, C.; Pufe, J.; Pietzsch, J.
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Clinical Hemorheology and Microcirculation 61(2015)2, 291-299
DOI: 10.3233/CH-151987
ISSN: 1386-0291
18F-Labeled 1,4-Dioxa-8-azaspiro[4.5]decane Derivative: Synthesis and Biological Evaluation of a σ1 Receptor Radioligand with Low Lipophilicity as Potent Tumor Imaging Agent
Xie, F.; Bergmann, R.; Kniess, T.; Deuther-Conrad, W.; Mamat, C.; et al. (11 authors)
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Journal of Medicinal Chemistry 58(2015), 5395-5407
DOI: 10.1021/acs.jmedchem.5b00593
ISSN: 0022-2623
Novel (pyrazolyl)benzenesulfonamides with a nitric oxide-releasing moiety as selective cyclooxygenase-2 inhibitors
Bechmann, N.; Kniess, T.; Köckerling, M.; Pigorsch, A.; Steinbach, J.; et al. (6 authors)
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Bioorganic & Medicinal Chemistry Letters 25(2015), 3295-3300
DOI: 10.1016/j.bmcl.2015.05.059
Cysteine cathepsins: their role in tumor progression and recent trends in the development of imaging probes
Löser, R.; Pietzsch, J.
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Frontiers in Chemistry 3(2015), 37
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Copper(II) cyclam complexes with N-propionic acid pendant arms
Kubeil, M.; Zarschler, K.; Pietzsch, J.; Kraus, W.; Comba, P.; et al. (6 authors)
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European Journal of Inorganic Chemistry 2015(2015), 4013-4023
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Novel indole-based sigma-2 receptor ligands: synthesis, structure–affinity relationship and antiproliferative activity
Xie, F.; Kniess, T.; Neuber, C.; Deuther-Conrad, W.; Mamat, C.; et al. (12 authors)
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MedChemComm 6(2015), 1093-1103
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Synthesis and Biodistribution Studies of 3H- and 64Cu-labeled Dendritic Polyglycerol and Dendritic Polyglycerol Sulfate
Pant, K.; Gröger, D.; Bergmann, R.; Pietzsch, J.; Steinbach, J.; et al. (13 authors)
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Bioconjugate Chemistry 26(2015), 906-918
DOI: 10.1021/acs.bioconjchem.5b00127
Development of indazolylpyrimidine derivatives as high-affine EphB4 receptor ligands and potential PET-radiotracers
Ebert, K.; Wiemer, J.; Caballero, J.; Köckerling, M.; Steinbach, J.; et al. (7 authors)
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Bioorganic & Medicinal Chemistry 23(2015), 6025-6035
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Optical imaging of COX-2: Studies on an autofluorescent 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitor.
Tondera, C.; Ullm, S.; Laube, M.; Meister, S.; Neuber, C.; et al. (8 authors)
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Biochemical and Biophysical Research Communications 458(2015), 40-45
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Cyclopeptides containing the DEKS motif as conformationally restricted collagen telopeptide analogues: synthesis and conformational analysis
Wodtke, R.; Ruiz-Gómez, G.; Kuchar, M.; Pisabarro, M. T.; Novotná, P.; et al. (9 authors)
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Organic & Biomolecular Chemistry 13(2015), 1878-1896
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Diaryl-substituted (dihydro)pyrrolo[3,2,1-hi]indoles, a class of potent COX-2 inhibitors with tricyclic core structure
Laube, M.; Gassner, C.; Sharma, S. K.; Günther, R.; Pigorsch, A.; et al. (10 authors)
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Journal of Organic Chemistry 80(2015), 5611-5624
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Effects of pulmonary acid aspiration on the regional pulmonary blood flow within the first hour after injury: an observational study in rats
Richter, T.; Bergmann, R.; Pietzsch, J.; Mueller, M. P.; Koch, T.
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Clinical Hemorheology and Microcirculation 60(2015), 253-262
Online First (2014) DOI: 10.3233/CH-141867
2014
Organotypical vascular model for characterization of radioprotective compounds: Studies on antioxidant 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitors
Ullm, S.; Laube, M.; Bechmann, N.; Knieß, T.; Pietzsch, J.
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Clinical Hemorheology and Microcirculation 58(2014), 281-295
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2,3-Diaryl-substituted indole based COX-2 inhibitors as leads for imaging tracer development
Laube, M.; Tondera, C.; Sharma, S. K.; Bechmann, N.; Pietzsch, F.-J.; et al. (10 authors)
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RSC Advances 4(2014), 38726-38742
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In Vivo Fluorescence Imaging and Urinary Monoamines as Surrogate Biomarkers of Disease Progression in a Mouse Model of Pheochromocytoma
Ullrich, M.; Bergmann, R.; Peitzsch, M.; Cartellieri, M.; Quin, N.; et al. (12 authors)
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Endocrinology 155(2014), 4149-4156
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ISSN: 0013-7227
Biocompatibility and inflammatory response in vitro and in vivo to gelatin-based biomaterials with tailorable elastic properties
Ullm, S.; Krüger, A.; Tondera, C.; Gebauer, T. P.; Neffe, A. T.; et al. (8 authors)
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Biomaterials 35(2014), 9755-9766
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Bispidine dioxotetraaza macrocycles: a new class of bispidines for 64Cu PET imaging
Comba, P.; Kubeil, M.; Pietzsch, J.; Rudolf, H.; Stephan, H.; et al. (6 authors)
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Inorganic Chemistry 53(2014), 6698-6707
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Radiofluorination and first radiopharmacological characterization of a SWLAY peptide-based ligand targeting EphA2
Pretze, M.; Mosch, B.; Bergmann, R.; Steinbach, J.; Pietzsch, J.; et al. (6 authors)
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Journal of Labelled Compounds and Radiopharmaceuticals 57(2014), 660-665
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Metastatic potential of B16-F10 melanoma cells is enhanced by extracellular S100A4 derived from RAW264.7 macrophages
Haase-Kohn, C.; Wolf, S.; Herwig, N.; Mosch, B.; Pietzsch, J.
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Biochemical and Biophysical Research Communications 446(2014), 143-148
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Radiolabeled anti-EGFR-antibody improves local tumor control after external beam radiotherapy and offers theragnostic potential
Koi, L.; Bergmann, R.; Brüchner, K.; Pietzsch, J.; Pietzsch, H.-J.; et al. (9 authors)
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Radiotherapy and Oncology 110(2014), 362-369
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Radiolabeled cetuximab conjugates for EGFR targeted cancer diagnostics and therapy
Sihver, W.; Pietzsch, J.; Krause, M.; Baumann, M.; Steinbach, J.; et al. (6 authors)
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Pharmaceuticals 7(2014)3, 311-338
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2013
Pulmonary Blood Flow Increases in Damaged Regions Directly after Acid Aspiration in Rats
Richter, T.; Bergmann, R.; Knels, L.; Hofheinz, F.; Kasper, M.; et al. (9 authors)
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Anesthesiology 119(2013), 890-900
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ISSN: 0003-3022
Synthesis and radiopharmacological evaluation of 64Cu-labeled bombesin analogs featuring a bis(2-pyridylmethyl) 1,4,7-triazacyclononane chelator
Bergmann, R.; Ruffani, A.; Graham, B.; Spiccia, L.; Steinbach, J.; et al. (7 authors)
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European Journal of Medicinal Chemistry 70(2013), 434-446
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Tissue transglutaminase: an emerging target for therapy and imaging
Pietsch, M.; Wodtke, R.; Pietzsch, J.; Löser, R.
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Bioorganic & Medicinal Chemistry Letters 23(2013)24, 6528-6543
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Optimization of Pentadentate Bispidines as Bifunctional Chelators for 64Cu Positron Emission Tomography (PET)
Comba, P.; Hunoldt, S.; Morgen, M.; Pietzsch, J.; Stephan, H.; et al. (6 authors)
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Inorganic Chemistry 52(2013), 8131-8143
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An Efficient Bioorthogonal Strategy Using CuAAC Click Chemistry for Radiofluorinations of SNEW Peptides and the Role of Copper Depletion
Pretze, M.; Kuchar, M.; Bergmann, R.; Steinbach, J.; Pietzsch, J.; et al. (6 authors)
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ChemMedChem 8(2013), 935-945
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Synthesis and radiopharmacological characterisation of a fluorine-18 labelled azadipeptide nitrile as potential PET Tracer for in vivo imaging of cysteine cathepsins
Löser, R.; Bergmann, R.; Frizler, M.; Mosch, B.; Dombrowski, L.; et al. (9 authors)
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ChemMedChem 8(2013), 1330-1344
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Recent trends in malignant melanoma biomarker research
Pietzsch, J.; Tandler, N.; Mosch, B.
- Clinical Laboratory International 37(2013), 6-8
Anti-tumor effects of peptide analogues targeting neuropeptide hormone receptors on mouse pheochromocytoma cells
Ziegler, C. G.; Eisenhofer, G.; Schally, A. V.; Gebauer, L.; Gondek, K.; et al. (11 authors)
-
Molecular and Cellular Endocrinology 371(2013), 189-194
DOI: 10.1016/j.mce.2012.12.011
ISSN: 0303-7207
Radiolabeled COX-2 inhibitors for non-invasive visualization of COX-2 expression and activity - a critical update
Laube, M.; Kniess, T.; Pietzsch, J.
-
Molecules 18(2013), 6311-6355
DOI: 10.3390/molecules18066311
Experimental hypoxia does not influence gene expression and protein synthesis of Eph receptors and ephrin ligands in human melanoma cells in vitro.
Reissenweber, B.; Mosch, B.; Pietzsch, J.
-
Melanoma Research 23(2013), 85-95
DOI: 10.1097/CMR.0b013e32835e58f3
Visualization of cyclooxygenase-2 using a 2,3-diarylsubstituted indole-based inhibitor and confocal laser induced cryofluorescence microscopy at 20 K in melanoma cells in vitro
Tondera, C.; Laube, M.; Wimmer, C.; Kniess, T.; Mosch, B.; et al. (7 authors)
-
Biochemical and Biophysical Research Communications 430(2013), 301-306
Online First (2012) DOI: 10.1016/j.bbrc.2012.10.133
Copper(II) chemistry of the functionalized macrocycle cyclam tetrapropionic acid
Comba, P.; Emmerling, F.; Jakob, M.; Kraus, W.; Kubeil, M.; et al. (8 authors)
-
Dalton Transactions 42(2013), 6142-6148
Online First (2012) DOI: 10.1039/C2DT32356G
2-Carbaborane-3-phenyl-1H-indoles—Synthesis via McMurry Reaction and Cyclooxygenase (COX) Inhibition Activity
Laube, M.; Neumann, W.; Scholz, M.; Lönnecke, P.; Crews, B.; et al. (9 authors)
-
ChemMedChem 8(2013)2, 329-335
DOI: 10.1002/cmdc.201200455
2012
Protein and non-protein biomarkers in melanoma: a critical update.
Tandler, N.; Mosch, B.; Pietzsch, J.
-
Amino Acids 6(2012), 2203-2230
DOI: 10.1007/s00726-012-1409-5
18F-Labeled phosphopeptide-cell-penetrating peptide dimers with enhanced cell uptake properties in human cancer cells
Richter, S.; Bouvet, V.; Wuest, M.; Bergmann, R.; Steinbach, J.; et al. (8 authors)
-
Nuclear Medicine and Biology 39(2012)8, 1202-1212
DOI: 10.1016/j.nucmedbio.2012.06.003
Fluorine-18-Radiolabeling and Radiopharmacological Characterization of a Benzodioxolylpyrimidine as a Radiotracer Targeting the Receptor Tyrosine Kinase EphB4
Mamat, C.; Mosch, B.; Neuber, C.; Köckerling, M.; Bergmann, R.; et al. (6 authors)
-
ChemMedChem 7(2012)11, 1991-2003
DOI: 10.1002/cmdc.201200264
Design, Evaluation, and Comparison of Ghrelin Receptor Agonists and Inverse Agonists as Suitable Radiotracers for PET Imaging
Chollet, C.; Bergmann, R.; Pietzsch, J.; Beck-Sickinger, A. G.
-
Bioconjugate Chemistry 23(2012), 771-784
DOI: 10.1021/bc2005889
Irradiation affects cellular properties and Eph receptor expression in human melanoma cells
Mosch, B.; Pietzsch, D.; Pietzsch, J.
-
Cell Adhesion & Migration 6(2012)2, 113-125
DOI: 10.4161/cam.20655
ISSN: 1933-6918
Specific targeting of hypoxic tumor tissue with nitroimidazole-peptide conjugates
Splith, K.; Bergmann, R.; Pietzsch, J.; Neundorf, I.
-
ChemMedChem 7(2012), 57-61
DOI: 10.1002/cmdc.201100401
Site-selective radiolabeling of peptides by 18F-fluorobenzoylation with [18F]SFB in solution and on solid phase - a comparative study
Kuchar, M.; Pretze, M.; Knieß, T.; Steinbach, J.; Pietzsch, J.; et al. (6 authors)
-
Amino Acids 43(2012), 1431-1443
DOI: 10.1007/s00726-012-1216-z
Radiosynthesis of a 18F-labeled 2,3-diarylsubstituted indole via McMurry coupling for functional characterization of cyclooxygenase-2 (COX-2) in vitro and in vivo
Kniess, T.; Laube, M.; Bergmann, R.; Graf, F.; Steinbach, J.; et al. (7 authors)
-
Bioorganic & Medicinal Chemistry 20(2012), 3410-3421
DOI: 10.1016/j.bmc.2012.04.022
2011
Synthesis of an 18F-labeled cyclin-dependent kinase-2 inhibitor
Svensson, F.; Kniess, T.; Bergmann, R.; Pietzsch, J.; Wuest, F.
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Journal of Labelled Compounds and Radiopharmaceuticals 54(2011), 769-774
DOI: 10.1002/jlcr.1922
S100A2 in cancerogenesis: a friend or a foe?
Wolf, S.; Haase-Kohn, C.; Pietzsch, J.
-
Amino Acids 41(2011), 849-861
DOI: 10.1007/s00726-010-0623-2
S100 proteins in health and disease
Pietzsch, J.
-
Amino Acids 41(2011), 755-760
DOI: 10.1007/s00726-010-0816-8
Copper-mediated cross-linking of S100A4, but not of S100A2, results in proinflammatory effects in melanoma cells
Haase-Kohn, C.; Wolf, S.; Lenk, J.; Pietzsch, J.
-
Biochemical and Biophysical Research Communications 413(2011), 494-498
DOI: 10.1016/j.bbrc.2011.08.132
Phosphopeptides with improved cellular uptake properties as ligands for the polo-box domain of polo-like kinase 1
Richter, S.; Neundorf, I.; Loebner, K.; Gräber, M.; Berg, T.; et al. (9 authors)
-
Bioorganic & Medicinal Chemistry Letters 21(2011), 4686-4689
DOI: 10.1016/j.bmcl.2011.06.103
Synthesis, characterization and biological evaluation of [188Re(N)(cys∼)(PNP)]+/0 mixed-ligand complexes as prototypes for the development of 188Re(N)-based target-specific radiopharmaceuticals
Thieme, S.; Agostini, S.; Bergmann, R.; Pietzsch, J.; Pietzsch, H.-J.; et al. (9 authors)
-
Nuclear Medicine and Biology 38(2011), 399-415
DOI: 10.1016/j.nucmedbio.2010.09.006
Synthesis and evaluation of 1,5-diaryl-substituted tetrazoles as novel selective cyclooxygenase-2 (COX-2) inhibitors
Al-Hourani, B. J.; Sharma, S. K.; Mane, J. Y.; Tuszynski, J.; Baracos, V.; et al. (9 authors)
-
Bioorganic & Medicinal Chemistry Letters 21(2011), 1823-1826
DOI: 10.1016/j.bmcl.2011.01.057
ISSN: 0960-894X
Expression, purification and fluorine-18 radiolabeling of recombinant S100A4: a potential probe for molecular imaging of receptor for advanced glycation endproducts in vivo?
Wolf, S.; Haase-Kohn, C.; Lenk, J.; Hoppmann, S.; Bergmann, R.; et al. (7 authors)
- Amino Acids 41(2011), 809-820
A Novel Tetrabranched Neurotensin(8-13) Cyclam Derivative: Synthesis, 64Cu-Labeling and Biological Evaluation
Röhrich, A.; Bergmann, R.; Kretzschmann, A.; Noll, S.; Steinbach, J.; et al. (7 authors)
-
Journal of Inorganic Biochemistry 105(2011), 821-832
DOI: 10.1016/j.jinorgbio.2011.02.011
Automated radiosynthesis of the thiol-reactive labeling agent N-[6-(4-[18F]fluorobenzylidene)aminooxyhexyl]maleimide ([18F]FBAM)
Knieß, T.; Kuchar, M.; Pietzsch, J.
-
Applied Radiation and Isotopes 69(2011), 1226-1230
DOI: 10.1016/j.apradiso.2011.03.043
2010
Modulation of Adrenal Aldosterone Release by Oxidative Modification of Low-Density Lipoprotein
Ansurudeen, I.; Pietzsch, J.; Graessler, J.; Ehrhart-Bornstein, M.; Saha, S.; et al. (7 authors)
-
American Journal of Hypertension 23(2010)10, 1061-1068
DOI: 10.1038/ajh.2010.118
ISSN: 0895-7061
Eph Receptors and Ephrin Ligands: Important Players in Angiogenesis and Tumor Angiogenesis
Mosch, B.; Reissenweber, B.; Neuber, C.; Pietzsch, J.
-
Journal of Oncology 2010(2010), 135285
DOI: 10.1155/2010/135285
Cyclin-Dependent Kinase 4/6 (Cdk4/6) Inhibitors: Perspectives in Cancer Therapy and Imaging
Graf, F.; Mosch, B.; Koehler, L.; Bergmann, R.; Wuest, F.; et al. (6 authors)
-
Mini-Reviews in Medicinal Chemistry 10(2010), 527-539
ISSN: 1389-5575
Synthesis of neurotensin(8-13)-phosphopeptide heterodimers via click chemistry
Richter, S.; Ramenda, T.; Bergmann, R.; Knieß, T.; Steinbach, J.; et al. (7 authors)
-
Bioorganic & Medicinal Chemistry Letters 20(2010), 3306-3309
DOI: 10.1016/j.bmcl.2010.04.038
ISSN: 0960-894X
Radiosynthesis and radiopharmacological evaluation of cyclin-dependent kinase 4 (Cdk4) inhibitors
Koehler, L.; Graf, F.; Bergmann, R.; Steinbach, J.; Pietzsch, J.; et al. (6 authors)
-
European Journal of Medicinal Chemistry 45(2010), 727-737
DOI: 10.1016/j.ejmech.2009.11.020
Scavenger receptors are associated with cellular interactions of S100A12 in vitro and in vivo
Hoppmann, S.; Steinbach, J.; Pietzsch, J.
-
International Journal of Biochemistry & Cell Biology 42(2010), 651-661
DOI: 10.1016/j.biocel.2009.12.010
Effects of posture on regional pulmonary blood flow in rats as measured by PET
Richter, T.; Bergmann, R.; Pietzsch, J.; Közle, I.; Hofheinz, F.; et al. (8 authors)
-
Journal of Applied Physiology 108(2010), 422-429
DOI: 10.1152/japplphysiol.91257.2008
Improved Multimodality Imaging Using Alginate Molding in Xenograft Tumor Models
Strobel, K.; Bergmann, R.; Meister, S.; van den Hoff, J.; Pietzsch, J.
-
Journal of Magnetic Resonance Imaging 31(2010), 747-752
DOI: 10.1002/jmri.22090
2009
Fluorine-18 labeling of phosphopeptides: a potential approach for the evaluation of phosphopeptide metabolism in vivo.
Richter, S.; Bergmann, R.; Pietzsch, J.; Ramenda, T.; Steinbach, J.; et al. (6 authors)
-
Biopolymers 92(2009)6, 479-488
DOI: 10.1002/bip.21263
Analysis of non-protein amino acids as specific markers of protein oxidation: the use of N(O,S)-ethoxycarbonyl ethyl ester and N(O,S)-ethoxycarbonyl trifluoroethyl ester derivatives and GC-MS
Pietzsch, J.; Pietzsch, F.-J.; Kopprasch, S.
- Trends in Chromatography 5(2009), 15-20
Influence of irradiation on metabolism and metastatic potential of B16-F10 melanoma cells
Mosch, B.; Müller, K.; Steinbach, J.; Pietzsch, J.
-
International Journal of Radiation Biology 85(2009)11, 1002-1012
DOI: 10.3109/09553000903258871
ISSN: 0955-3002
Reduction of Arteriosclerotic Nanoplaque Formation and Size by n-3 Fatty Acids in Patients after Valvular Defect Operation
Koppe, C.; Rodriguez, M.; Winkler, K.; Pietzsch, J.; Neumann, K.; et al. (9 authors)
-
Forschende Komplementärmedizin / Research in Complementary Medicine 16(2009), 237-245
DOI: 10.1159/000229786
Fluorine-18 radiolabeling of native and oxidized proteins: An important tool in the pathophysiologists toolbox
Pietzsch, J.; Wuest, F.
- Chimica Oggi - Chemistry Today 27(2009), 12-14
Fluorine-18-radiolabeled S100A12: a potential probe for functional characterization of inflammatory processes in vivo
Hoppmann, S.; Richter, S.; Steinbach, J.; Pietzsch, J.
-
Inflammation Research 58(2009)Suppl. 2, S145-S146
ISSN: 1023-3830
Synthesis and cyclooxygenase inhibition of various (aryl-1,2,3-triazole-1-yl)-methanesulfonylphenyl derivatives
Wuest, F.; Tang, X.; Knieß, T.; Pietzsch, J.; Suresh, M.
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Bioorganic & Medicinal Chemistry 17(2009), 1146-1151
DOI: 10.1016/j.bmc.2008.12.032
Radiosynthesis and radiopharmacological evaluation of [N-methyl-11C]Org 34850 as a glucocorticoid receptor (GR)-binding radiotracer
Wüst, F.; Knieß, T.; Henry, B.; Peeters, B. W. M. M.; Wiegerinck, P. H. G.; et al. (7 authors)
-
Applied Radiation and Isotopes 67(2009), 308-312
DOI: 10.1016/j.apradiso.2008.10.014
Prediabetic and diabetic in vivo modification of circulating low density lipoprotein attenuates its stimulatory effect on adrenal mineralocorticoid secretion
Kopprasch, S.; Pietzsch, J.; Ansurudeen, I.; Graessler, J.; Krug, A. W.; et al. (7 authors)
-
Journal of Endocrinology 200(2009), 45-52
DOI: 10.1677/JOE-08-0293
Validation of 99mTc-labeled "4+1" fatty acids for myocardial metabolism and flow imaging Part 2: Subcellular distribution
Mirtschink, P.; Stehr, S. N.; Walther, M.; Pietzsch, J.; Bergmann, R.; et al. (13 authors)
-
Nuclear Medicine and Biology 36(2009), 845-852
DOI: 10.1016/j.nucmedbio.2009.06.003
Validation of 99mTc-labeled "4+1" fatty acids for myocardial metabolism and flow imaging Part 1: Myocardial extraction and biodistribution
Mirtschink, P.; Stehr, S. N.; Walther, M.; Pietzsch, J.; Bergmann, R.; et al. (13 authors)
-
Nuclear Medicine and Biology 36(2009), 833-843
DOI: 10.1016/j.nucmedbio.2009.06.009
Cell cycle regulating kinase Cdk4 as a potential target for tumor cell treatment and tumor imaging
Graf, F.; Köhler, L.; Knieß, T.; Wüst, F.; Mosch, B.; et al. (6 authors)
-
Journal of Oncology 2009(2009), 106378
DOI: 10.1155/2009/106378
Human S100A12: a novel key player in inflammation?
Pietzsch, J.; Hoppmann, S.
-
Amino Acids 36(2009), 381-389
DOI: 10.1007/s00726-008-0097-7
ISSN: 0939-4451 (Print) 14
Systematic comparison of two novel thiol-reactive prosthetic groups for 18F labeling of peptides and proteins with the acylation agent succinimidyl-4-[18F]fluorobenzoate [18F]SFB
Wüst, F.; Köhler, L.; Berndt, M.; Pietzsch, J.
-
Amino Acids 36(2009), 283-295
ISSN: 0939-4451
2008
Effects of pioglitazone and/or simvastatin on low density lipoprotein subfractions in non-diabetic patients with high cardiovascular risk: A sub-analysis from the PIOSTAT study
Leonhardt, W.; Pfützner, A.; Müller, J.; Pietzsch, J.; Forst, T.; et al. (8 authors)
-
Atherosclerosis 201(2008), 155-162
DOI: 10.1016/j.atherosclerosis.2008.01.007
Synthesis and evaluation in vitro and in vivo of a 11C-labeled cyclooxygenase-2 (COX-2) inhibitor
Wüst, F.; Knieß, T.; Bergmann, R.; Pietzsch, J.
-
Bioorganic & Medicinal Chemistry 16(2008), 7662-7670
DOI: 10.1016/j.bmc.2008.07.016
Yttrium-86-labelled human serum albumin microspheres: relation of surface structure with in vivo stability
Schiller, E.; Bergmann, R.; Pietzsch, J.; Noll, B.; Sterger, A.; et al. (8 authors)
-
Nuclear Medicine and Biology 35(2008), 227-232
DOI: 10.1016/j.nucmedbio.2007.10.008
Synthesis and Application of [18F]FDG-maleimidehexyloxime ([18F]FDG-MHO): A [18F]FDG-based Prosthetic Group for the Chemoselective 18F-Labeling of Peptides and Proteins
Wüst, F.; Berndt, M.; Bergmann, R.; van den Hoff, J.; Pietzsch, J.
- Bioconjugate Chemistry 19(2008)6, 1202-1210
Radiolabeled glucocorticoids as molecular probes for imaging brain glucocorticoid receptors by means of positron-emission-tomography (PET)
Steiniger, B.; Knieß, T.; Bergmann, R.; Pietzsch, J.; Wüst, F.
-
Mini-Reviews in Medicinal Chemistry 8(2008)7, 728-739
ISSN: 1389-5575
Radiosynthesis of n.c.a. sodium [18F]fluoroacetate and radiopharmacological characterization in rats and tumour-xenografted mice
Richter, S.; Bergmann, R.; Pietzsch, J.; Beuthien-Baumann, B.; Wüst, F.
-
Current Radiopharmaceuticals 1(2008)2, 103-109
ISSN: 1874-4710
Expression, purification and fluorine-18 radiolabeling of recombinant S100 proteins - potential probes for molecular imaging of receptor for advanced glycation endproducts (RAGE) in vivo
Hoppmann, S.; Haase, C.; Richter, S.; Pietzsch, J.
-
Protein Expression and Purification 57(2008)2, 143-152
DOI: 10.1016/j.pep.2007.10.009
Glycoxidation of low-density lipoprotein in impaired glucose tolerance: implications for the pathogenesis of diabetic vascular disease
Kopprasch, S.; Graessler, J.; Bornstein, S. R.; Pietzsch, J.
-
Vascular Disease Prevention 5(2008), 24-28
ISSN: 1567-2700
Localized proton magnetic resonance spectroscopy of lipids in adipose tissue at high spatial resolution in mice in vivo
Strobel, K.; van den Hoff, J.; Pietzsch, J.
-
Journal of Lipid Research 49(2008), 473-480
DOI: 10.1194/jlr.D700024-JLR200
Modified 4+1 Mixed Ligand Technetium Labeled Fatty Acids for Myocardial Imaging: Evaluation of Myocardial Uptake and Biodistribution
Mirtschink, P.; Stehr, S. N.; Pietzsch, H.-J.; Bergmann, R.; Pietzsch, J.; et al. (12 authors)
-
Bioconjugate Chemistry 19(2008), 97-108
DOI: 10.1021/bc700164c
2007
Factors influencing the formation of small dense low-density lipoprotein particles in dependence on the presence of the metabolic syndrome and on the degree of glucose intolerance
Julius, U.; Dittrich, M.; Pietzsch, J.
-
International Journal of Clinical Practice 61(2007)11, 1798-1804
DOI: 10.1111/j.1742-1241.2007.01507.x
Myocardial uptake and biodistribution of newly designed technetium-labelled fatty acid analogues
Heintz, A. C.; Jung, C. M.; Stehr, S. N.; Mirtschink, P.; Walther, M.; et al. (12 authors)
-
Nuclear Medicine Communications 28(2007)8, 637-647
ISSN: 0143-3636
Experimental hypoxia is a potent stimulus for radiotracer uptake in vitro: Comparison of different tumor cells and primary endothelial cells
Oswald, J.; Treite, F.; Haase, C.; Kampfrath, T.; Mäding, P.; et al. (8 authors)
-
Cancer Letters 254(2007), 102-110
DOI: 10.1016/j.canlet.2007.02.016
[18F]FBAM and [18F]FBOM: Novel Thiol-reactive prosthetic groups derived from 4-[18F]fluorobenzaldehyde
Vogler, L.; Berndt, M.; Pietzsch, J.; Wüst, F.
- Journal of Labelled Compounds and Radiopharmaceuticals 50(2007), 1276-1286
L-Type Amino Acid Transporters LAT1 and LAT4 in Cancer: Uptake of 3-O- Methyl-6-18F-Fluoro-L-Dopa (18F-OMFD) in Human Adenocarcinoma and Squamous Cell Carcinoma in vitro and in vivo
Haase, C.; Bergmann, R.; Füchtner, F.; Hoepping, A.; Pietzsch, J.
-
Journal of Nuclear Medicine 48(2007)12, 2063-2071
DOI: 10.2967/jnumed.107.043620
Glycoxidised LDL isolated from subjects with impaired glucose tolerance increases CD36 and peroxisome proliferator-activator receptor gamma gene expression in macrophages
Graessler, J.; Pietzsch, J.; Westendorf, T.; Julius, U.; Bornstein, S. R.; et al. (6 authors)
-
Diabetologia 50(2007)5, 1080-1088
DOI: 10.1007/s00125-007-0645-9
ISSN: 0012-186X
Lipid transfer protein activities in subjects with impaired glucose tolerance
Julius, U.; Jauhiainen, M.; Ehnholm, C.; Pietzsch, J.
-
Clinical Chemistry and Laboratory Medicine 45(2007)2, 237-243
ISSN: 1434-6621
Labeling of low-density lipoproteins using the 18F-labeled thiol-reactive reagent N-[6-(4-[18F]fluorobenzylidene)aminooxyhexyl]maleimide [18F]FBAM
Berndt, M.; Pietzsch, J.; Wüst, F.
-
Nuclear Medicine and Biology 34(2007), 5-15
DOI: 10.1016/j.nucmedbio.2006.09.009
Synthesis of 18F-labelled stilbenes from 4-[18F]fluorobenzaldehyde using the Horner-Wadsworth-Emmons reaction
Gester, S.; Pietzsch, J.; Wüst, F.
-
Journal of Labelled Compounds and Radiopharmaceuticals 50(2007)2, 105-113
DOI: 10.1002/jlcr.1172
Synthesis and radiopharmacological characterization of [11C]AL-438 as a nonsteroidal ligand for imaging brain glucocorticoid receptors
Wüst, F.; Knieß, T.; Bergmann, R.; Henry, B.; Pietzsch, J.
- Bioorganic & Medicinal Chemistry Letters 17(2007), 4035-4039
Synthesis and biological evaluation of a new type of 99mTechnetium-labeled fatty acid for myocardial metabolism imaging
Walther, M.; Jung, C.; Bergmann, R.; Pietzsch, J.; Rode, K.; et al. (15 authors)
-
Bioconjugate Chemistry 18(2007), 216-230
ISSN: 10.1021/bc0601222
2006
Neurotensin Receptors in Adeno- and Squamous Cell Carcinoma
Haase, C.; Bergmann, R.; Oswald, J.; Zips, D.; Pietzsch, J.
- Anticancer Research 26(2006), 3527-3534
Biodistribution and catabolism of 18F-labeled N-epsilon-fructoselysine as a model of Amadori products
Hultsch, C.; Hellwig, M.; Pawelke, B.; Bergmann, R.; Rode, K.; et al. (8 authors)
-
Nuclear Medicine and Biology 33(2006), 865-873
DOI: 10.1016/j.nucmedbio.2006.07.007
2005
Positron emission tomography in food sciences
Pietzsch, J.; van den Hoff, J.
-
Amino Acids 29(2005)4, 303-305
DOI: 10.1007/s00726-005-0198-5
ISSN: 0939-4451
Small animal positron emission tomography in food sciences
Bergmann, R.; Pietzsch, J.
-
Amino Acids 29(2005)4, 355-376
DOI: 10.1007/s00726-005-0237-2
ISSN: 0939-4451
Biodistribution and catabolism of 18F-labelled isopeptide N (varepsilon)-(gamma-glutamyl)-L-lysine
Hultsch, C.; Bergmann, R.; Pawelke, B.; Pietzsch, J.; Wüst, F.; et al. (7 authors)
-
Amino Acids 29(2005)4, 405-413
DOI: 10.1007/s00726-005-0204-y
ISSN: 0939-4451
Catabolism of native and oxidized low density lipoproteins (LDL): in vivo insights from small animal positron emission tomography studies
Pietzsch, J.; Bergmann, R.; Wüst, F.; Pawelke, B.; Hultsch, C.; et al. (6 authors)
-
Amino Acids 29(2005)4, 389-404
DOI: 10.1007/s00726-005-0203-z
ISSN: 0939-4451
Glucose-Induced Enhancement of Hemin-Catalyzed LDL Oxidation In Vitro and In Vivo
Julius, U.; Pietzsch, J.
- Antioxidants and Redox Signaling 7(2005)11-12, 1507-1512
Pathological consequenses of systemic oxidative stress and dyslipidemia in impaired glucose tolerance and diabetes mellitus
Kopprasch, S.; Grässler, J.; Pietzsch, J.
- Trends in Cell & Molecular Biology 1(2005), 1-14
In vivo metabolism of oxidized low density lipoproteins: Insights from small animal positron emission tomography (PET) studies
Pietzsch, J.; Bergmann, R.; Wüst, F.; van den Hoff, J.
- Recent Research Developments in Molecular & Cellular Biochemistry 2(2005), 153-177
Synthesis and biodistribution of an 18F-labelled resveratrol derivative for small animal positron emission tomography (PET)
Gester, S.; Wüst, F.; Pawelke, B.; Bergmann, R.; Pietzsch, J.
-
Amino Acids 29(2005)4, 415-428
DOI: 10.1007/s00726-005-0205-x
ISSN: 0939-4451
2004
Fluorine-18 radiolabeling of low-density lipoproteins: a potential approach for characterization and differentiation of metabolism of native and oxidized low-density lipoproteins in vivo.
Pietzsch, J.; Bergmann, R.; Rode, K.; Hultsch, C.; Pawelke, B.; et al. (7 authors)
- Nuclear Medicine and Biology 31(2004), 1043-1050
3-O-Methyl-6-18F-Fluoro-L-Dopa, a New Tumor Imaging Agent: Investigation of Transport Mechanism In Vitro
Bergmann, R.; Pietzsch, J.; Füchtner, F.; Pawelke, B.; Beuthien-Baumann, B.; et al. (7 authors)
- Journal of Nuclear Medicine 45(2004), 2116-2122
The effect of garlic on arteriosclerotic nanoplaque formation and size
Siegel, G.; Malmsten, M.; Pietzsch, J.; Schmidt, A.; Buddecke, E.; et al. (8 authors)
- Phytomedicine 11(2004), 24-35
Oxidativ modifizierte Lipoproteine und deren Antikörper bei Patienten mit Antiphospholipid-Syndrom
Roch, B.; Kopprasch, S.; Pietzsch, J.; Schröder, H.
-
Zeitschrift für Rheumatologie (2004) 63(2004), 331-337
DOI: 10.1007/s00393-004-0601-8
The pivotal role of scavenger receptor CD36 and phagocyte-derived oxidants in oxidized low density lipoprotein-induced adhesion to endothelial cells
Kopprasch, S.; Pietzsch, J.; Westendorf, T.; Kruse, H.-J.; Graessler, J.
- International Journal of Biochemistry and Cell Biology 36(2004)3, 460-471
The protective effects of HDL and its constituents against neutrophil respiratory bust activation by hypochlirite-oxidized LDL
Kopprasch, S.; Pietzsch, J.; Graessler, J.
- Molecular and Cellular Biochemistry 258(2004), 121-127
Analysis of non-protein amino acids as specific markers of low density lipoprotein apolipoprotein B-100 oxidation in human atherosclerotic lesions: the use of N(O,S)-ethoxycarbonyl trifluoroethyl ester derivatives and GC-MS
Pietzsch, J.; Bergmann, R.; Kopprasch, S.
- Spectroscopy 18(2004),177-183
Analysis of 6-hydroxy-2-aminocaproic acid (HACA) as a specific marker of protein oxidation: The use of N(O,S)-ethoxycarbonyl trifluoroethyl ester derivatives and gas chromatography/mass spectrometry
Pietzsch, J.; Bergmann, R.
- Amino Acids 26(2004), 45-51
2003
Validation of different chemilumigenic substrates for detecting extracellular generation of reactive oxygen species by phagocytes and endothelial cells
Kopprasch, S.; Pietzsch, J.; Graessler, J.
- Luminescence (2003) 18: 268-273
Fortschritte in der Aminosäureanalytik: N(O,S)-Ethoxycarbonyl-(trifluoro)ethylester-Derivate
Pietzsch, J.
- Bioforum 10/2003, 643-645
Measurement of 5-hydroxy-2-aminovaleric acid as a specific marker of iron-mediated oxidation of proline and arginine residues of low density lipoprotein aplipoprotein B-100 in human atherosclerotic lesions
Pietzsch, J.; Bergmann, R.
- J Clin Pathol (2003) 56: 622-623
Flavonoide: Wirkmechanismen und neue Anwendungsmöglichkeiten (Teil 2)
Pietzsch, J.; Bergmann, R.; Wüst, F.
- Bioforum (2003) 6:384-385
Flavonoide: Wirkmechanismen und neue Anwendungsmöglichkeiten (Teil 1)
Pietzsch, J.; Bergmann, R.; Wüst, F.
- Bioforum (2003) 5: 289-291
Increased cholesteryl ester transfer protein (CETP) activity in impaired glucose tolerance: relationship to high density lipoprotein metabolism
Pietzsch, J.; Fücker, K.
- Croatian Medical Journal 44 (2): 171-177, 2003
Lack of association between serum paraoxonase (PON1) activities and increased oxidized LDL levels in impaired glucose tolerance and newly diagnosed diabetes mellitus
Kopprasch, S.; Pietzsch, J.; Kuhlisch, E.; Gräßler, J.
- Journal of Clinical Endocrinology & Metabolism 2003; 88: 1711-1716
Analysis of 3-chlorotyrosine as a specific marker of protein oxidation: The use of N(O,S)-ethoxycarbonyl trifluoroethyl ester derivatives and gas chromatography/mass spectrometry
Pietzsch, J.; Kopprasch, S.; Bergmann, R.
- Rapid Commun. Mass Spectrom 17 (2003):767-770
2002
Intraindividual comparison of two extracorporeal LDL apheresis methods: lipidfiltration and HELP
Julius, U.; Metzler, W.; Pietzsch, J.; Fassbender, T.; Klingel, R.
- Int J Artif Organs 25 (2002): 1180-1188
In vivo evidence for increased oxidation of circulating LDL in impaired glucose tolerance
Kopprasch, S.; Pietzsch, J.; Kuhlisch, E.; Fuecker, K.; Temelkova-Kurktschiev, T.; et al. (9 authors)
- Diabetes 51 (2002) 3102-3106
Impaired glucose tolerance is not associated with lipid intolerance
Henkel, E.; Temelkova-Kurtschiev, T.; Köhler, C.; Pietzsch, J.; Leonhardt, W.; et al. (6 authors)
- Diab Nutr Metab 15 (2002) 84-90
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